Preprint Brief Report Version 1 This version is not peer-reviewed

Genotypes and Subgenotypes of Hepatitis B Virus, Circulating in Belarus

Version 1 : Received: 25 October 2024 / Approved: 28 October 2024 / Online: 28 October 2024 (13:28:43 CET)

How to cite: Eremin, V.; Karpenko, F.; Karpov, I.; Semenov, V.; Oiestad, I. Genotypes and Subgenotypes of Hepatitis B Virus, Circulating in Belarus. Preprints 2024, 2024102145. https://doi.org/10.20944/preprints202410.2145.v1 Eremin, V.; Karpenko, F.; Karpov, I.; Semenov, V.; Oiestad, I. Genotypes and Subgenotypes of Hepatitis B Virus, Circulating in Belarus. Preprints 2024, 2024102145. https://doi.org/10.20944/preprints202410.2145.v1

Abstract

As studies have shown, out of all 884 sequenced and analyzed samples, 722 (81.7%) of them have genotype D; 156 (17.7%) - genotype A; 3 (0.3%) - genotype C and the only 1 (0.1%) – genotype B. For two cases (0.2%) a recombinant form of the hepatitis B virus was detected. Genotype D was found representing by subgenotypes D1 (145/20.1%), D2 (371/51.4%), D3 (201/27, 8%) and D4 (5/0.7%); A – A2; C – C1 and C2; B – B4; recombinant forms C2/ D and A2/ С2 were detected. The epidemic process of hepatitis B in the country is supported mainly by the circulation of “local” variants of the virus. At the same time, there are occasional introductions of new variants from outside the country.

Keywords

HBV; genotypes/subgenotypes; sequencing; phylogenetic analysis

Subject

Biology and Life Sciences, Virology

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