Lactate to albumin ratio and mortality in patients with severe Coronavirus Disease-2019 admitted to intensive care unit

Christina Routsi; Stelios Kokkoris; Aikaterini Gkoufa; Dimitrios Katsaros; Stavros Karageorgiou; Fotios Kavalieratos; Dimitrios Tsilivarakis; Georgia Dimopoulou; Evangelia Theodorou; Mizi Eleftheria; Anastasia Kotanidou; Ioanna Dimopoulou

doi:10.20944/preprints202410.2172.v1

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preprints.org > medicine and pharmacology > epidemiology and infectious diseases > doi: 10.20944/preprints202410.2172.v1 (registering DOI)

Preprint Article Version 1 This version is not peer-reviewed

Lactate to albumin ratio and mortality in patients with severe Coronavirus Disease-2019 admitted to intensive care unit

^* ,

Dimitrios Tsilivarakis

Version 1 : Received: 28 October 2024 / Approved: 28 October 2024 / Online: 28 October 2024 (14:05:13 CET)

How to cite: Routsi, C.; Kokkoris, S.; Gkoufa, A.; Katsaros, D.; Karageorgiou, S.; Kavalieratos, F.; Tsilivarakis, D.; Dimopoulou, G.; Theodorou, E.; Eleftheria, M.; Kotanidou, A.; Dimopoulou, I. Lactate to albumin ratio and mortality in patients with severe Coronavirus Disease-2019 admitted to intensive care unit. Preprints 2024, 2024102172. https://doi.org/10.20944/preprints202410.2172.v1 Routsi, C.; Kokkoris, S.; Gkoufa, A.; Katsaros, D.; Karageorgiou, S.; Kavalieratos, F.; Tsilivarakis, D.; Dimopoulou, G.; Theodorou, E.; Eleftheria, M.; Kotanidou, A.; Dimopoulou, I. Lactate to albumin ratio and mortality in patients with severe Coronavirus Disease-2019 admitted to intensive care unit. Preprints 2024, 2024102172. https://doi.org/10.20944/preprints202410.2172.v1

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MDPI and ACS Style

Routsi, C.; Kokkoris, S.; Gkoufa, A.; Katsaros, D.; Karageorgiou, S.; Kavalieratos, F.; Tsilivarakis, D.; Dimopoulou, G.; Theodorou, E.; Eleftheria, M.; Kotanidou, A.; Dimopoulou, I. Lactate to albumin ratio and mortality in patients with severe Coronavirus Disease-2019 admitted to intensive care unit. Preprints 2024, 2024102172. https://doi.org/10.20944/preprints202410.2172.v1

APA Style

Routsi, C., Kokkoris, S., Gkoufa, A., Katsaros, D., Karageorgiou, S., Kavalieratos, F., Tsilivarakis, D., Dimopoulou, G., Theodorou, E., Eleftheria, M., Kotanidou, A., & Dimopoulou, I. (2024). Lactate to albumin ratio and mortality in patients with severe Coronavirus Disease-2019 admitted to intensive care unit. Preprints. https://doi.org/10.20944/preprints202410.2172.v1

Chicago/Turabian Style

Routsi, C., Anastasia Kotanidou and Ioanna Dimopoulou. 2024 "Lactate to albumin ratio and mortality in patients with severe Coronavirus Disease-2019 admitted to intensive care unit" Preprints. https://doi.org/10.20944/preprints202410.2172.v1

Abstract

Aim: This study sought to evaluate the effectiveness of lactate/albumin ratio for ICU mortality prediction in a large cohort of patients with severe Coronavirus Disease-2019 (COVID-19) admitted to the intensive care unit (ICU). Methods: This is a single-center retrospective cohort study of prospectively collected data derived from the COVID-19 dataset for all critically ill patients admitted to an academic ICU. Data were used to determine the relation between lactate/albumin ratio and other laboratory parameters measured on the first day of ICU stay and to evaluate the prognostic performance for ICU mortality prediction. Results: A total of 805 ICU patients were included, the median age (IQR) was 67 (57-76) years, with 68% being male. ICU mortality was 48% and the median lactate/albumin ratio was 0.53 (0.39-0.59). Survival analysis showed that patients with higher lactate/albumin ratio values had significantly lower survival rates (Log Rank p

Keywords

lactate, albumin, Covid-19, SARS-CoV-2, sepsis, outcome, ICU

Subject

Medicine and Pharmacology, Epidemiology and Infectious Diseases

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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