Preprint Article Version 1 This version is not peer-reviewed

Health-Related Quality of Life and Functional Status of Post-COVID-19 Patients

Version 1 : Received: 30 October 2024 / Approved: 30 October 2024 / Online: 31 October 2024 (11:47:31 CET)

How to cite: Oliveira, M.; Alves, L.; Soares, J.; Souza, S.; Fonseca, A.; Silva, C.; Oliveira, C.; Vieira, R.; Oliveira, D.; Oliveira-Silva, I.; Oliveira, R.; Sampaio, L.; Maldaner, V.; Santos, D.; Palma, R.; Nacif, S.; Insalaco, G.; Oliveira, L.; Silva, B. Health-Related Quality of Life and Functional Status of Post-COVID-19 Patients. Preprints 2024, 2024102479. https://doi.org/10.20944/preprints202410.2479.v1 Oliveira, M.; Alves, L.; Soares, J.; Souza, S.; Fonseca, A.; Silva, C.; Oliveira, C.; Vieira, R.; Oliveira, D.; Oliveira-Silva, I.; Oliveira, R.; Sampaio, L.; Maldaner, V.; Santos, D.; Palma, R.; Nacif, S.; Insalaco, G.; Oliveira, L.; Silva, B. Health-Related Quality of Life and Functional Status of Post-COVID-19 Patients. Preprints 2024, 2024102479. https://doi.org/10.20944/preprints202410.2479.v1

Abstract

Background: COVID-19 mainly affects the respiratory system, although its manifestations are multisystemic. Increasingly, complications presented after the acute phase are still being rec-ognized and are associated with impaired functional status and health-related quality of life (HRQoL). The objective was assess the functional status and HRQoL of patients with post-COVID-19. Methods: This was a cross-sectional study involving individuals affected by COVID-19 who had persistent symptoms for one month after the acute phase of the disease. HRQoL was verified through the Short Form Health Survey 36 (SF-36) and, functional status was assessed using the six-minute walk test (6MWT), the Fatigue Severity Scale (FSS), the Med-ical Research Council (MRC) Dyspnea Scale and, the Post-COVID-19 Functional Status Scale (PCFS). Results: Were included 123 patients, 73 (59.35%) were male, with a mean age of 49.17±13.48 years and a body mass index of 31.02±6.56 stratified into three groups, not recov-ered group (NRG=23), ward recovered group (WHG=60), and intensive care unit group (ICUG=40). The main symptoms were muscle weakness (74.17%) and dyspnea (68.33%). In rela-tion to the distance covered in the 6MWT, the GNR group walked 12.83% below the predicted values, GNR 20.21% and the UGCI 28.82%, respectively. The MRC dyspnea scale had a mean value of less than 3 and the FSS scale had a mean value over 4, indicating considerable fatigue. In the PCFS scale, a significant difference was observed (p>0.0005); while in the SF-36, all HRQoL domains were compromised. Conclusion: Post-COVID-19 patients involved in this study showed a significant decline in functional status and an impairment of HRQoL.

Keywords

COVID-19; functional status; health-related quality of life

Subject

Biology and Life Sciences, Life Sciences

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