Version 1
: Received: 30 October 2024 / Approved: 31 October 2024 / Online: 31 October 2024 (09:59:35 CET)
How to cite:
Sarma, A.; Suri, P.; Justice, M.; Angamuthu, R.; Pushparaj, S. Role of Long Noncoding RNAs in Chicken Viral Diseases. Preprints2024, 2024102537. https://doi.org/10.20944/preprints202410.2537.v1
Sarma, A.; Suri, P.; Justice, M.; Angamuthu, R.; Pushparaj, S. Role of Long Noncoding RNAs in Chicken Viral Diseases. Preprints 2024, 2024102537. https://doi.org/10.20944/preprints202410.2537.v1
Sarma, A.; Suri, P.; Justice, M.; Angamuthu, R.; Pushparaj, S. Role of Long Noncoding RNAs in Chicken Viral Diseases. Preprints2024, 2024102537. https://doi.org/10.20944/preprints202410.2537.v1
APA Style
Sarma, A., Suri, P., Justice, M., Angamuthu, R., & Pushparaj, S. (2024). Role of Long Noncoding RNAs in Chicken Viral Diseases. Preprints. https://doi.org/10.20944/preprints202410.2537.v1
Chicago/Turabian Style
Sarma, A., Raja Angamuthu and Samuel Pushparaj. 2024 "Role of Long Noncoding RNAs in Chicken Viral Diseases" Preprints. https://doi.org/10.20944/preprints202410.2537.v1
Abstract
Poultry farming faces significant challenges due to viral diseases, which lead to high mortality and economic losses. Long noncoding RNAs (lncRNAs) have emerged as crucial regulators in the host immune response to viral infections. This review explores the multifaceted roles of lncRNAs in chicken viral diseases, including avian leukosis, Marek’s disease, infectious bursal disease, avian influenza, infectious bronchitis, and Newcastle disease. LncRNAs influence gene expression at various levels, such as chromatin remodeling, transcriptional regulation, and post-transcriptional modifications. They interact with viral and host genes, modulating immune responses and viral replication processes. Specific lncRNAs, such as ERL lncRNA, linc-GALMD3, and loc107051710, have been identified as key players in the pathogenesis and immune response to these viral infections. Understanding the mechanisms of lncRNA action provides insights into potential diagnostic and therapeutic strategies to enhance disease resistance in poultry. This review highlights the importance of lncRNAs in the complex interplay between host and virus, paving the way for future research and applications in poultry health management.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.