Preprint Article Version 1 This version is not peer-reviewed

Effectiveness of Early Versus Late Time-Restricted Eating Combined with Physical Activity in Overweight or Obese Women

Version 1 : Received: 31 October 2024 / Approved: 1 November 2024 / Online: 1 November 2024 (09:52:37 CET)

How to cite: Miladi, S.; Driss, T.; Ameur, R.; Miladi, S. C.; Miladi, S. J.; Najjar, M. F.; Neffati, F.; Hammouda, O. Effectiveness of Early Versus Late Time-Restricted Eating Combined with Physical Activity in Overweight or Obese Women. Preprints 2024, 2024110034. https://doi.org/10.20944/preprints202411.0034.v1 Miladi, S.; Driss, T.; Ameur, R.; Miladi, S. C.; Miladi, S. J.; Najjar, M. F.; Neffati, F.; Hammouda, O. Effectiveness of Early Versus Late Time-Restricted Eating Combined with Physical Activity in Overweight or Obese Women. Preprints 2024, 2024110034. https://doi.org/10.20944/preprints202411.0034.v1

Abstract

To evaluate the effectiveness of a dual approach involving time-restricted eating (TRE) at different times-of-day combined with physical activity (PA) on functional capacity and metabolic health in overweight or obese women. Random allocation of sixty-one participants into four groups: early time-restricted eating plus physical activity (ETRE-PA, n=15, 31.8±10.56 years, 89.68±10.56 kg, 33.5±5.53 kg/m²), late time-restricted eating with physical activity (LTRE-PA, n=15, 30.60±7.94 years, 94.45±15.36 kg, 34.37±7.09 kg/m²), late time-restricted eating only (LTRE, n=15, 27.93±9.79 years, 88.32±10.36 kg, 32.71±5.15 kg/m²) and a control group (CG, n=15, 36.25±11.52 years, 89.01±11.68 kg, 33.66±6.18 kg/m²). The intervention lasted 12 weeks for all groups. Both ETRE-PA and LTRE-PA groups engaged in a rigorous combined aerobic and resistance-training program. Significant reductions in body weight and body mass index were observed in ETRE-PA and LTRE-PA compared to CG and LTRE groups in post-intervention (p<0.0005). Only ETRE-PA group exhibited a significant decrease in fat mass (p=0.02), low-density lipoprotein cholesterol (p=0.01) and aspartate aminotransferase (p=0.002). Significant reductions in alanine aminotransferase levels were observed in ETRE-PA (p=0.004) and LTRE-PA (p=0.02) groups. These two latter groups achieved higher performances in the 6-min walking test, bench press, 30-second squat, crunch test, vertical jump (p<0.0005 for both) and leg extension (p<0.02 for both) when compared to LTRE and CG groups. In conclusion, the integration of TRE with PA leads to greater improvements in body composition, lipid profile, and physical performance with no significant differences between ETRE-PA and LTRE-PA approaches. This combined strategy offers a promising solution in overweight or obese women.

Keywords

Time-restricted eating; circadian rhythms; metabolic health, physical performance

Subject

Public Health and Healthcare, Physical Therapy, Sports Therapy and Rehabilitation

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