Preprint Article Version 1 This version is not peer-reviewed

MRI Liver Segmentation Protocol Enables More Consistent and Robust Annotations Paving the Way for Advanced Computer-Assisted Analysis

Version 1 : Received: 2 November 2024 / Approved: 4 November 2024 / Online: 4 November 2024 (14:33:51 CET)

How to cite: Jeltsch, P.; Monnin, K.; Jreige, M.; Fernandes-Mendes, L.; Girardet, R.; Dromain, C.; Richiardi, J.; Vietti-Violi, N. MRI Liver Segmentation Protocol Enables More Consistent and Robust Annotations Paving the Way for Advanced Computer-Assisted Analysis. Preprints 2024, 2024110198. https://doi.org/10.20944/preprints202411.0198.v1 Jeltsch, P.; Monnin, K.; Jreige, M.; Fernandes-Mendes, L.; Girardet, R.; Dromain, C.; Richiardi, J.; Vietti-Violi, N. MRI Liver Segmentation Protocol Enables More Consistent and Robust Annotations Paving the Way for Advanced Computer-Assisted Analysis. Preprints 2024, 2024110198. https://doi.org/10.20944/preprints202411.0198.v1

Abstract

Background/Objectives: Recent advancements in artificial intelligence (AI) have spurred interest in developing computer-assisted analysis for imaging examinations. However, the lack of high-quality datasets remains a significant bottleneck. Labeling instructions are critical to improving dataset quality but are often lacking. This study aimed to establish a liver MRI segmentation protocol and assess its impact on annotation quality and inter-reader agreement; Methods: This retrospective study included 20 patients with chronic liver disease. Manual liver segmentations were performed by a radiologist in training and a radiology technician on T2 weighted imaging (wi) and T1wi at the portal venous phase. Based on the inter-reader discrepancies identified after the first segmentation round, a segmentation protocol was established, guiding the second round of segmentation, resulting in a total of 160 segmentations. Dice Similarity Coefficient (DSC) assessed inter-reader agreement pre- and post-protocol with a Wilcoxon signed-rank test. Slice selection at extreme cranial or caudal liver positions was evaluated using the McNemar test; Results: The per-volume DSC significantly increased after protocol implementation for both T2wi (p

Keywords

segmentation; liver; MRI; computer-assisted analysis; radiomics; deep learning

Subject

Computer Science and Mathematics, Artificial Intelligence and Machine Learning

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