The digital transformation of supply chain management has emerged as a strategic imperative in response to the complexities of today’s interconnected and fast-paced business environment. This paper investigates the transformative role of digital technologies, such as the Internet of Things, big data analytics, artificial intelligence, blockchain, and cloud computing, in enhancing supply chain efficiency, agility, and resilience. By enabling real-time communication, network visibility, and data-driven decision-making, these technologies empower organizations to address contemporary challenges and unlock new opportunities for innovation and optimization. Using a rigorous methodological approach, including Principal Component Analysis, correlation matrix examination, and multiple regression analysis, this research provides empirical insights into the relationship between digital transformation and supply chain management efficiency. Findings reveal that connectivity is a critical enabler of transparency, collaboration, and responsiveness across supply chain networks. A balanced approach that integrates internal process optimization with robust external partnerships is essential to maximize digital transformation benefits. The findings underscore the strategic imperative of adopting digital technologies to achieve sustained competitiveness, resilience, and innovation in the evolving global supply chain landscape.