The use of centrifugal pumps for water supply and distribution applications is evident in every industry as they efficiently transport fluid from a certain point. However, the sector faces severe concerns regarding its operating efficiency due to accumulated losses and sudden power consumption growth. Thus, it is crucial to find a remedy to mitigate these concerns and improve the performance of the centrifugal pump. This study aims to provide an improved design of centrifugal water pumps by analyzing the effects of changing its design parameters. Splitter blades, with a length of 80% of the main blade, will be included in the design. Using ANSYS software to generate a baseline design model, CFD analysis will be conducted. Then, an optimization study will be performed using the Response Surface Method (RSM) to formulate an optimized design. Results indicate that finding a perfect balance between the placement of the splitter blades, the design of the volute tongue clearance and thickness, and configuring the ellipse ratio of the splitter blades improves the pump's performance. The optimal design results in 27.35%, 15.70%, 28.18%, 16.67%, and 8.36% improvement in total efficiency, total head, static efficiency, static head, and power consumption, respectively.