Within this work we review the metal coordination effect on the photophysics of metal dipyrrinato complexes. Dipyrrinato complexes are promising candidates in the search for alternative transition metal photosensitizers for application in photodynamic therapy (PDT). These complexes can be activated by irradiation with light of a specific wavelength, after which cytotoxic reactive oxygen species (ROS) are generated. The metal coordination allows for the use of the heavy atom effect, which can enhance the triplet generation necessary for generation of ROS. Additionally, the flexibility of these complexes for metal ions, substitutions and ligands allows the possibility to tune their photophysical properties. A general overview of the mechanism of photodynamic therapy and the properties of the triplet photosensitizers is given, followed by further details of dipyrrinato complexes described in the literature that show relevance as photosensitizers for PDT. In particular, the photophysical properties of Re(I), Ru(II), Ir(III), Ni(II), Cu(II), Pd(II), Pt(II), Zn(II), Ga(III), In(III), Al(III), Sn(II), and P dipyrrinato complexes are discussed. The potential for future development in the field of (dipyrrinato)metal complexes is addressed and several new research topics are suggested throughout this work. We propose that significant advances could be made for heteroleptic bis(dipyrrinato)zinc(II) and homoleptic bis(dipyrrinato)palladium(II) complexes and their application as photosensitizers for PDT.

This paper presents a study on optimization of Overcurrent relay (OCR) coordination protection scheme for Sustainable Standalone Hydrokinetic Renewable Energy (SHRE) distribution network at Batang Rajang river, located at Kapit Sarawak, Malaysia by turning river stream into power generation source. The purpose of the project is to develop rural electrification system for native long houses along the river. The research study is tested on a DigSILENT develop model of the SHRE distribution network and in accordance with all respectively unique parameters and relevant standards. Since this is a new standalone distribution system, an efficient and properly coordinated overcurrent protection system must be provided. Improper and miscoordination among OCRs result in maloperation of the protection system that can lead to false tripping and an unnecessary outage and power system instability. Thus, the objective of this work is to employ Genetic Algorithm (GA) technique in Matlab/Simulink for optimal overcurrent coordination and settings among all OCRs in the proposed distribution network in order to improve the speed of OCR tripping operation. The GA is used because the project is fast track and requiring the simplest method available. In this strategy, time dial setting (TDS) is optimized by using plug setting multiplier (PSM) as the constraint. The obtained results show a significant improvement of the relay operating time of 36.01% faster than that of conventional numerical technique during fault occurrence. Thus, an efficient and reliable overcurrent protection scheme has been achieved for the SHRE distribution network.

Ankle sprains are the most frequently occurring musculoskeletal injuries among recreational athletes. Ankle support through bandages following the initial orthotic treatment might be beneficial for rehabilitation purposes. Since hardly any study has investigated the impact of bandages in the acute phase of ankle sprains, our study examined the immediate effects of wearing an ankle bandage on fine coordination, proprioception, and motor performance in subjects five weeks after an acute ankle injury. In total, 70 subjects with acute unilateral supination trauma were tested. All subjects completed several rating questionnaires and biomechanical investigations, including a fine coordination and proprioception test, single leg stances, the Y-Balance test and gait analysis. All biomechanical investigations were conducted for the subject's injured leg with and without a bandage (MalleoTrain® Bauerfeind AG) and the healthy leg. Subjects reported moderate to strong improvements in ankle stability and pain when wearing the bandage. Wearing the bandage significantly normalized subjects’ single leg stance performance, as well as the stance phase duration, and the vertical ground reaction forces during walking. However, the bandage did not have a clear effect on fine coordination and proprioception. Wearing a bandage in the acute phase of an ankle sprain may immediately improve motor performance, including standing and walking.