First Detection of Neuroinvasive Porcine Astroviruses With Multiple Genotypes in South Korea

Jun-Soo Park; Chang-Gi Jeong; Su-Beom Chae; Sook-Young Lee; Jae-Ku Oem

doi:10.20944/preprints202306.0381.v1

Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Version 1 : Received: 2 June 2023 / Approved: 6 June 2023 / Online: 6 June 2023 (07:06:03 CEST)

Recently, astroviruses (AstVs) have been associated with neurological symptoms in pigs, cattle, sheep, minks, muskoxes, alpacas, and humans. To investigate genotypes of porcine astrovirus (PAstV) and neuroinvasive (Ni) PAstV in South Korea, five domestic pigs with neurological symptoms from three farms were tested using reverse transcriptase PCR, histopathology, and in situ hybridization (ISH). All five genotypes of PAstV were detected in brain tissues and coinfection of PAstV with multiple genotypes was observed. To the best of our knowledge, this is the first study to report pig infection by Ni-PAstV with multiple genotypes in South Korea.

Astrovirus; Porcine; Encephalitis; Myelitis

Biology and Life Sciences, Virology

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First Detection of Neuroinvasive Porcine Astroviruses With Multiple Genotypes in South Korea

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