ARTICLE
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doi:10.20944/preprints202211.0080.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Tumor initiation; Germ cell traits of tumors; Primordial germ cell-like tumor cells; Somatic to Pri-mordial germ cell-like transformation; Embryonic/germ cell hypothesis of tumor; Breast cancer
Online: 4 November 2022 (01:04:58 CET)
REVIEW
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doi:10.20944/preprints202402.0456.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
Keywords: keyword triggering receptor expressed in myeloid cells-like transcript (TLT-1); blood platelets; cardiovascular diseases; left ventricular ejection fraction (LVEF); biomarker; anthracyclines, Troponin I, cardiotoxicity, congestive heart failure (CHF)
Online: 7 February 2024 (17:08:39 CET)
HYPOTHESIS
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
environment; virus; pollutant; evolution; exaptation; stem cells; transposons; APOBEC; ADAR,; ORF2p; cancer; Eco-Evo-Devo; symbiosis; ecological genomics; environmental stress; genetic recombination; biological plasticity; hypermutation; epigenetics; fractal systems; natural selection
Online: 19 July 2020 (19:35:46 CEST)
ARTICLE
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doi:10.20944/preprints201901.0245.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
Osteomeles Schwerinae; diabetic retinopathy (DR); spontaneously diabetic Torii (SDT) rat; human retinal microvascular endothelial cells (HRMECs); advanced glycation end products (AGEs); retinal apoptosis; oxidative stress; mitochondrial function; adjunctive effect; combination therapy
Online: 24 January 2019 (08:37:29 CET)
HYPOTHESIS
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doi:10.20944/preprints202109.0372.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Endometriosis; microchimerism; maternal microchimerism; reproduction; gynaecology; etiology; auto-immune; immune response; hormonal; vascular; genetic; hereditary; male; fetal; fetus; stem cells; pregnancy; Műllerianosis; embryology; ROS; apoptosis; disease; endometrium; basalis; menstruation; post-menopausal; neurogenesis
Online: 22 September 2021 (10:27:52 CEST)
ARTICLE
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
protein/rna world; plasma membrane; cytoplasm; virus world; pre-retro virus; emergence of dna; transcription and replication; first cells; hyperthermophiles; luca; bacteria and archaea; anoxygenic bacteria; oxygenic bacteria; global distribution of cyanobacteria
Online: 15 October 2019 (11:18:58 CEST)
REVIEW
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doi:10.20944/preprints202403.1200.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Mast cells; Sentinel cell; Health; Ovulation; Pregnancy; Inflammation; Wound healing; Cell prolif-eration; Angiogenesis; bFGF; VEGF-A; Tissue remodeling; Histamine; Serotonin; Heparin; Proteases; IL-1-alpha; IL-8; TNF-alpha; Nitric oxide; Survival; Progeny
Online: 20 March 2024 (09:50:02 CET)
ARTICLE
Subject:
Environmental And Earth Sciences,
Paleontology
Keywords:
protein/RNA world: plasma membrane; cytoplasm; gene regulation; virus world; pre-retro virus; emergence of DNA; transcription and replication; first cells; hyperthermophiles; LUCA; Bacteria and Archaea; anoxygenic bacteria; oxygenic bacteria; global distribution of cyanobacteria
Online: 12 February 2020 (03:25:07 CET)
ARTICLE
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doi:10.20944/preprints202309.1265.v1
Subject:
Engineering,
Other
Keywords:
Multijunction solar cells; IIIV semiconductors; TCAD simulation; cell optimization; predictive profiling; CIGS absorbers; spectral utilization; currentvoltage characteristics; external quantum efficiency; GaAs replacement; bottom junction; thin films; high efficiency; photovoltaics; epitaxial growth; stacked junctions; light absorption
Online: 19 September 2023 (07:48:35 CEST)
REVIEW
Subject:
Medicine And Pharmacology,
Psychiatry And Mental Health
Keywords:
multiple sclerosis; MS; cause; genes; polygenic; heredity; autoimmune; diet; depression; fatigue; suicide; seizures; bowel disorders; thyroid; mitochondria; chromosome 2; chromosome 5; glial cells; sunlight; vitamin D3; ultraviolet radiation; melanocyte stimulating hormone; melanocyte concentrating hormone; stress
Online: 22 July 2019 (04:37:27 CEST)
REVIEW
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doi:10.20944/preprints202407.1456.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
advanced therapy medicinal products (ATMPs); chimeric antigen receptors (CAR-T cells); B acute lymphoblastic leukaemia (B-ALL); food and drug administration (FDA); systemic lupus erythematosus (SLE); idiopathic inflammatory myositis (IIM); systemic sclerosis (SS); memorial sloan kettering cancer centre (MSKCC); hematopoietic stem cell transplantation [HSCT], non-Hodgkin’ s cell lymphoma (NHCL); multiple myeloma (MM); follicular lymphoma; (FL); large B cell-lymphoma (LBCL); mantle cell lymphoma (MCL); myeloid-derived suppressor cells (MDSCs); rheumatoid arthritis (RA); immune effector cell-associated neurotoxicity syndrome (ICANS); natural killer group member D ligands (NKG2DLs); acute myelogenous leukaemia (AML)
Online: 18 July 2024 (08:03:12 CEST)
ARTICLE
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doi:10.20944/preprints201810.0088.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
There are many molecules used as drug carrier. TUD-1 is a newly synthesized mesoporous silica (SM) molecule possess two important features; consists of mesoporous so it is very suitable to be drug carrier in addition to that it has the ability to induce apoptosis in cancer cells. However, the effect of TUD-1 appears to act as cell death inducer, regardless of whether it is necrosis or apoptosis. Unfortunately, recent studies indicate that a proportion of cells undergo necrosis rather than apoptosis, which limits the use of TUD-1 as a secure treatment. On the other hand, lithium considered as necrosis inhibitor element. Hence, current study based on the idea of production a new Li/TUD-1 by incorporated mesoporous silica (TUD-1 type) with lithium in order to produce a new compound that has the ability to activate apoptosis by mesoporous silica (TUD-1 type) and at the same time can inhibit the activity of necrosis by lithium. Herein, lithium was incorporated in TUD-1 mesoporous silica by
Online: 4 October 2018 (15:54:02 CEST)
REVIEW
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doi:10.20944/preprints202303.0500.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
Oxidative stress and cell death; Reactive oxygen species; ROS; ROS cell death; autophagy; role of antioxidants; eye disease; cornea; lens; epithelium; retinal ganglion cells; retinal pigment epithelium; macular degeneration; antioxidants in the macula; oxidative stress prevention with antioxidants; lifestyle changes; digital eye strain; glaucoma; cataracts; dry eye disease; computer vision syndrome; digital eye strain; diabetic retinopathy; Vitamin A; Vitamin C; copper; glutathione; zinc; selenium; magnesium; blue light damage; UV light damage; blue light reactive oxygen species; autophagy; ferroptosis; ROS cell death; superoxide dismutase; optic nerve gliomas; food deserts; myopia; free radicals
Online: 29 March 2023 (03:33:55 CEST)