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Preprint ARTICLE | doi:10.20944/preprints202210.0150.v1

Multilevel and Multiregional Analysis of the Electricity Metabolism Across Sectors

Natalie Ortiz-Guerrero, Rafael González-López

Subject: Engineering, Electrical And Electronic Engineering Keywords: MuSIASEM; multilevel; multiregionlal; electricity; Mexico

Online: 11 October 2022 (10:35:16 CEST)

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This paper presents a novel improvement of MuSIASEM (Multiscale Integrated Analysis of the Societal and Ecological Metabolism) by incorporating a new regional analysis of the electricity metabolism across levels. An analysis of Mexico illustrates this toolkit and shows that the industry sector had Economic Energy Intensity (EEI) with 40.3 MWh/MMXN reached a higher value than the commerce and services sector with 0.84 MWh/MMXN. Regarding the Economic Labor Productivity (ELP) indicator (AV/h), the industrial sector with 208.5 TMXN/Kh reached a higher value than the Commercial and services sector with 114.3 TMXN/Kh. With reference to the Exosomatic Metabolic Rate (EMR), the Household sector obtained 59.3 KWh/Kh whereas the paid sector reached 2,486.4 KWh/Kh. Disaggregation of the EMR indicator into economic sectors shows that the Industrial sector obtained 8.4 KWh/Kh and the commercial and services sector reached 0.10 KWh/Kh. The lack of complete data for the agricultural sector does not allow us to calculate EEI, ELP, and EMR indicators accurately. Considering the analysis of indicators by regions, regarding the EEI rate, the Central region had the lowest value with 12.7 MWh/MMXN, followed by the Northeast with 21.4 MWh/MMXN and Western with 29.4 MWh/ MMXN, which means that they require less electricity to produce more added value. In terms of the ELP indicator, it was found regions with higher values were Northeast with 182.3 MMXN/Mh, Central with 177.5 MMXN/Mh, and North with 127 MMXN/Mh, which means that these regions produce more added value per hour of work. About the EMR, it is observed that regions in the northern part of the country had higher values: Northwest with 337 KWh/Kh, Baja California Sur with 334 KWh/Kh, Baja California with 328 KWh/Kh, North with 313 KWh/Kh and Northeast with 274 KWh/Kh, which means that these regions consume more electricity per hour. This innovative approach is useful for governance because it helps to understand and reduce asymmetries across regions, resulting in more social equality and a better economic equilibrium across sectors and regions.

Preprint REVIEW | doi:10.20944/preprints202202.0180.v2

Redox Homeostasis and Nitro-Oxidative Stress in Obesity-Linked Inflammation

Guillaume Treiber, Hanen Samouda, Estelle Nobécourt, Serge P. Bottari

Subject: Medicine And Pharmacology, Endocrinology And Metabolism Keywords: oxidative stress; nitrative stress; reactive oxygen species; reactive nitrogen species; nitric oxide inflammation; obesity; peroxynitrite; adipose tissue

Online: 30 September 2022 (11:10:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202209.0350.v1

Black Hole Entropy from Non-Dirichlet Sectors, and Bounce Solution

Inyong Park

Subject: Physical Sciences, Acoustics Keywords: black hole entropy; non-Dirichlet boundary condition; bounce

Online: 23 September 2022 (02:06:59 CEST)

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Preprint REVIEW | doi:10.20944/preprints202209.0339.v1

Vertebrate Animal Models of RP59: Current Status and Future Prospects

Steven J. Fliesler, Sriganesh Ramachandra Rao, Mai N. Nguyen, Mahmoud Tawfik KhalafAllah, Steven J. Pittler

Subject: Medicine And Pharmacology, Ophthalmology Keywords: cis-prenyltransferase; DHDDS; dolichol; Nogo-B receptor; retinal degeneration; RP59

Online: 22 September 2022 (10:18:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202104.0207.v5

Exponentials and Logarithms Properties in an Extended Complex Number Field

Daniel Tischhauser

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: Complex number field; Complex exponentiation; Complex logarithm; Exponential and logarithm identities

Online: 14 September 2022 (03:53:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202207.0399.v9

New Concepts of Time and Matter Supported by Fifteen Proofs

Markolf H. Niemz, Siegfried W. Stein

Subject: Physical Sciences, Quantum Science And Technology Keywords: theory of everything; relativity; spacetime; cosmology; background radiation; Hubble’s law; Hubble constant; dark energy; wave–particle duality; quantum entanglement

Online: 6 September 2022 (03:44:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202209.0070.v1

Density and Velocity Analysis of the Planetary Nebula NGC 6853

Robert Hrubý

Subject: Physical Sciences, Astronomy And Astrophysics Keywords: Nebula; NGC 6853; Stellar; Planetary nebula; Deep space; remnant

Online: 5 September 2022 (14:08:07 CEST)

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Preprint REVIEW | doi:10.20944/preprints202209.0034.v1

Working from Home, Telework, and Psychological Wellbeing? A Systematic Review

Joseph Crawford

Subject: Business, Economics And Management, Business And Management Keywords: remote work; telework; systematic literature review; work design; workforce planning

Online: 2 September 2022 (05:54:08 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202208.0547.v1

Intraspecific Leaf Trait Variation Across and Within Wine Grape Varieties

Samantha C. Macklin, Rachel O. Mariani, Emily N. Young, Rosalyn Kish, Kimberley A. Cathline, Gavin Robertson, Adam R. Martin

Subject: Biology And Life Sciences, Ecology, Evolution, Behavior And Systematics Keywords: Agroecology; functional trait; intraspecific trait variation; Leaf Economics Spectrum; plant trait spectra; Vitis vinifera.

Online: 31 August 2022 (13:35:02 CEST)

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Preprint REVIEW | doi:10.20944/preprints202208.0539.v1

A Review of Methods used to Monitor and Predict Droughts

Hushiar Raheem Hamarash, Azad Rasul, Rahel Othman Hamad

Subject: Environmental And Earth Sciences, Environmental Science Keywords: drought monitoring; drought predictions; drought indices; drought models

Online: 31 August 2022 (08:47:06 CEST)

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Preprint REVIEW | doi:10.20944/preprints202208.0468.v1

Mechanistic insights into the biochemical and pharmacological profile of esculetin

Sourbh Suren Garg, Jeena Gupta, Debasis Sahu, Chuan Ju Liu

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: esculetin; cancer; oxidative stress; inflammation; arthritis; diabetes; fatty liver

Online: 29 August 2022 (05:25:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202208.0421.v1

Older Physical Education Teachers’ Wellbeing at Work and its Challenges

Henry Lipponen, Mirja Hirvensalo, Kasper Salin

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: physical education; older employee; ageing; work ability; coping at work; wellbeing at work

Online: 24 August 2022 (11:07:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202208.0310.v1

Human Resource Management and Selected Personnel Indicators in Sustainable Development

Viera Sukalova, Zuzana Stofkova, Jana Stofkova

Subject: Social Sciences, Psychology Keywords: human resource management; personnel audit; personnel indicators; Covid-19 pandemic

Online: 17 August 2022 (08:45:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202208.0290.v1

Human Resource Management and Selected Personnel Indicators in Sustainable Development

Viera Sukalova, Zuzana Stofkova, Jana Stofkova

Subject: Business, Economics And Management, Human Resources And Organizations Keywords: human resource management; personnel politics; personnel indicators; Covid-19 Pandemic

Online: 16 August 2022 (11:56:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202208.0191.v1

Snakemake Workflows for Long-read Bacterial Genome Assembly and Evaluation

Peter Menzel

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: bacterial genomics; de novo assembly; Oxford Nanopore Technologies; Snakemake

Online: 10 August 2022 (04:37:01 CEST)

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Preprint REVIEW | doi:10.20944/preprints202208.0163.v1

STAT3 and Its Pathways Dysregulation – Underestimated Role in Urological Tumors

Maciej Golus, Piotr Bugajski, Joanna Chorbińska, Wojciech Krajewski, Artur Lemiński, Jolanta Saczko, Julita Kulbacka, Tomasz Szydełko, Bartosz Małkiewicz

Subject: Medicine And Pharmacology, Urology And Nephrology Keywords: STAT3; prostate cancer; bladder cancer; upper tract urothelial carcinoma; renal cell carcinoma; penile cancer; testicular cancer

Online: 8 August 2022 (15:09:21 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202208.0156.v1

Static Load Characteristics of Hydrostatic Journal Bearings: Measurements and Predictions

Howon Yi, Hyunsung Jung, Kyuman Kim, Keun Ryu

Subject: Engineering, Mechanical Engineering Keywords: Hydrostatic bearings; Journal bearings; Static load characteristics; Measurements; Predictions

Online: 8 August 2022 (10:57:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202208.0143.v1

Molecular Epidemiology and Virulence of Non-Typhoidal Salmonella in Armenia

Anahit Sedrakyan, Zhanna Ktsoyan, Karine Arakelova, Zaruhi Gevorgyan, Magdalina Zakharyan, Shoghik Hakobyan, Alvard Hovhannisyan, Arsen Arakelyan, Rustam Aminov

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: non-typhoidal Salmonella; ERIC-PCR typing; WGS; virulence-related genes; SPIs; Salmonella virulence plasmids; prophages

Online: 8 August 2022 (10:07:34 CEST)

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Preprint REVIEW | doi:10.20944/preprints202208.0120.v1

Mine Tailings-Based Geopolymers: Durability, Microstructure, Thermal and Leaching Properties

Xiang He

Subject: Engineering, Civil Engineering Keywords: Mine Tailings; Industrial Waste; Geopolymer; ‎Durability; Microstructure; Thermal; Leaching

Online: 5 August 2022 (09:45:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202208.0103.v1

Oxidized Resveratrol Metabolites as Potent Antioxidants and Xanthine Oxidase Inhibitors

Orinamhe G. Agbadua, Norbert Kúsz, Róbert Berkecz, Tamás Gáti, Gábor Tóth, Attila Hunyadi

Subject: Chemistry And Materials Science, Medicinal Chemistry Keywords: Resveratrol; antioxidant metabolism; scavengome; biomimetic oxidation; bioactivity-guided isolation; NMR spectroscopy; xanthine oxidase

Online: 4 August 2022 (05:33:52 CEST)

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Preprint REVIEW | doi:10.20944/preprints202208.0089.v1

Serotonin as a Biocultural Molecule: Circular Causality, Stress, and Psychopathology

Caio Maximino

Subject: Social Sciences, Behavior Sciences Keywords: Serotonin; Chemical imbalance theories of psychopathology; Circular causality; Biocultural psychopathology; Critical neuroscience

Online: 3 August 2022 (11:24:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202208.0076.v1

Semi-Analytical Lower-Bound Limit Analysis of Domes and Vaults

Renato Zona, Luca Esposito, Simone Palladino, Elena Totaro, Vincenzo Minutolo

Subject: Engineering, Civil Engineering Keywords: Limit analysis of domes; Concrete caps; experiment comparison; Not Tensile Resistant Materials; Finite element

Online: 3 August 2022 (07:20:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202208.0059.v1

The Staphylococcus Epidermidis RP62A Metabolic Network: Validation and Intervention Strategies

Francisco Guil, Guillermo Sánchez-Cid, José Manuel García

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Staphylococcus epidermidis; metabolic network validation; minimal cut sets; knock-outs; systems biology

Online: 2 August 2022 (09:33:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202206.0050.v2

Harvesting Context and Mining Emotions Related to Olfactory Cultural Heritage

M.Besher Massri, Inna Novalija, Dunja Mladenić, Janez Brank, Sara Graça da Silva, Natasza Marrouch, Carla Murteira, Ali Hürriyetoğlu, Beno Šircelj

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Emotions Mining; Context Mining; Sensory Mining; Artificial Intelligence; Information extraction; Text classification; Fairy tales; Olfactory Cultural Heritage

Online: 2 August 2022 (07:57:35 CEST)

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Preprint REVIEW | doi:10.20944/preprints202208.0021.v1

Bioavailability Enhancement Techniques for Poorly Aqueous Soluble Drugs and Therapeutics

Arvind Kumar Singh Chandel, Dixit Bhalani, Nutan Bhingaradiya, Avinash Kumar

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: Solubility; Bioavailability; Dissolution; Poorly Soluble Drugs; Drug Solubility Enhancement Techniques

Online: 1 August 2022 (10:44:13 CEST)

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The low water solubility of any pharmacoactive molecules limits their pharmacological potential but the solubility parameter cannot compromise, so different approaches are employed to enhance their bioavailability. Pharmaceutically active molecules with low solubility convey a higher risk of failure for drug innovation and development. Pharmacokinetics, pharmacodynamics, and several other parameters, such as drug distribution, protein binding and absorption, are majorly affected by their solubility. Among all pharmaceutical dosage forms, the oral dosage forms cover more than 50 %, and the drug molecule should be water-soluble. For good therapeutic activity by the drug molecule on the target site, solubility and bioavailability are crucial factors. The pharmaceutical industry screening programs identified that around 40% of new chemical entities (N.C.E.s) face various difficulties at the formulation and development step. These pharmaceuticals are attributed to their less solubility and bioavailability. The bioavailability and drug solubility enhancement are significant challenges in the area of pharmaceutical formulations. According to the Classification of Biopharmaceutics, Class II and IV drugs (APIs) exhibits poor solubility, lower bioavailability, and less dissolution. Various technologies are discussed in this article to improve the solubility of the poorly water-soluble drug, for example, complexation of active molecules, utilization of emulsion formation, micelles, microemulsions, cosolvents, polymeric micelles preparation, particle size reduction technologies, pharmaceutical salts, prodrugs, solid-state alternation technique, soft gel technology, drug nanocrystals, solid dispersion methods, crystal engineering techniques and nanomorph technology. This review mainly describes several other advanced methodologies for solubility and bioavailability enhancement, such as crystal engineering, micronization, solid dispersions, nano sizing, use of cyclodextrins, solid lipid nanoparticles, colloidal drug delivery systems and drug conjugates, by some appropriate research reports.

Preprint REVIEW | doi:10.20944/preprints202207.0379.v1

Leukotrienes vs. Montelukast – Activity, Metabolism, and Toxicity Hints for Repurposing

Cátia F. Marques, M. Matilde Marques, Gonçalo C. Justino

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Montelukast; Leukotrienes; Adverse drug reactions; Repurposing

Online: 26 July 2022 (03:27:37 CEST)

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Preprint SHORT NOTE | doi:10.20944/preprints202207.0302.v1

Machine Learning Application in G.I.S. and Remote Sensing: An Overview

Anjeel Upreti

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: machine learning; artificial intelligence; pattern; models; classification; regression; GIS; remote sensing

Online: 20 July 2022 (10:58:15 CEST)

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Preprint REVIEW | doi:10.20944/preprints202207.0245.v1

Biological and Cosmetical Importance of Fermented Raw Materials: An Overview

Weronika Majchrzak, Ilona Motyl, Krzysztof Śmigielski

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: bioferments; natural cosmetics; fermentation; bioactive compounds

Online: 18 July 2022 (03:38:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202207.0179.v1

Telegram Channels and Bots: A Ranking of Spanish Media Oulets

Víctor Herrero-Solana, Carlos Castro-Castro

Subject: Social Sciences, Library And Information Sciences Keywords: Telegram; media; Spain; channels; bots; fake channels; rankings

Online: 12 July 2022 (09:13:54 CEST)

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Preprint REVIEW | doi:10.20944/preprints202207.0171.v1

The Effects of Chronic Stress on Neuroanatomy and Cognitive Function

Niki Viradia, Jesica Godinez Paredes, Syed Hassan

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Alzheimer’s; aging; amygdala; brain plasticity; CA1; CA3; chronic stress; cognition; GABA; HIF-1; hippocampus; hypoxia; neurogenesis; Parkinson’s; prefrontal cortex; PSA-NCAM; ROS; spatial learning

Online: 12 July 2022 (04:25:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202207.0168.v1

Failed Emancipations: Youth Transitions, Migration and the Future in Morocco

José Sánchez-García, Carles Feixa, Celia Premat, Nele Hansen

Subject: Social Sciences, Anthropology Keywords: Transition; Emancipation; Youth; Morocco

Online: 12 July 2022 (04:09:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202207.0167.v1

Cryobanking European Mink (Mustela lutreola) Mesenchymal Stem Cells and Oocytes

Alexandra Calle, Miguel Ángel Ramírez

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: European mink; ex situ conservation; biobank; mesenchymal stem/stromal cells

Online: 12 July 2022 (04:04:08 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202207.0137.v1

Upper and Lower H^m Estimates for Solutions to Dissipative Systems

Robert Guterres, César Niche, Cilon Perusato, Paulo Zingano

Subject: Computer Science And Mathematics, Analysis Keywords: dissipative systems; upper and lower estimates; decay estimates; monotonicity method

Online: 8 July 2022 (10:13:41 CEST)

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Preprint REVIEW | doi:10.20944/preprints202207.0118.v1

Potential Properties of Natural Nutraceuticals and Antioxidants in Eye Protection

Jessica Maiuolo, Rosamaria Bulotta, Francesca Oppedisano, Vincenzo Musolino, Micaela Gliozzi, Cristina Carresi, Federica Scarano, Saverio Nucera, Miriam Scicchitano, Martina Nicita, Rosamaria Caminiti, Francesca Bosco, Roberta Macrì, Adriano Carnevali, Vincenzo Scorcia, Vincenzo Mollace

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Eyes diseases; Oxidative damage; Antioxidant compounds; Vitamin A; Vitamin C; Lutein; Curcumin; Quercetin; Coenzyme Q10; PUFAs; BPF; Grape seed

Online: 7 July 2022 (09:04:14 CEST)

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Preprint REVIEW | doi:10.20944/preprints202207.0024.v1

Kinases and Their Potential as Therapeutic Targets in Huntington’s Disease

Angel White, Anna McGlone, Rocio Gomez-Pastor

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: post-translation modifications; CK2; Huntington’s Disease; Kinase Inhibition; HTT phosphorylation

Online: 1 July 2022 (17:47:10 CEST)

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Preprint REVIEW | doi:10.20944/preprints202206.0285.v1

Analysis of Blockchain in the Healthcare Sector: Application and Issues

Ammar Odeh, Ismail Keshta, Qasem Abu Al-Haija

Subject: Computer Science And Mathematics, Analysis Keywords: Blockchain; Healthcare; Privacy; Cybersecurity; Healthcare-records

Online: 21 June 2022 (05:05:50 CEST)

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Preprint REVIEW | doi:10.20944/preprints202206.0284.v1

Building Consensus around the Assessment and Interpretation of Symbiodiniaceae Diversity

Sarah Davies, Matthew H. Gamache, Lauren I. Howe-Kerr, Nicola G. Kriefall, Andrew C. Baker, Anastazia T. Banaszak, Line K. Bay, Anthony J. Bellantuono, Debashish Bhattacharya, Cheong Xin Chan, Danielle C. Claar, Mary Alice Coffroth, Ross Cunning, Simon K. Davy, Javier del Campo, Erika M. Diaz-Almeyda, Jorg C. Frommlet, Lauren E. Fuess, Raul A. Gonzalez-Pech, Tamar L. Goulet, Kenneth D. Hoadley, Emily J. Howells, Benjamin C. C. Hume, Dustin W. Kemp, Carly, D. Kenkel, Sheila A. Kitchen, Todd C. LaJeunesse, Senjie Lin, Shelby McIlroy, Ryan McMinds, Matthew R. Nitschke, Clinton A. Oakley, Raquel S. Peixoto, Carlos Prada, Hollie M. Putnam, Kate Quigley, Hannah G. Reich, James Davis Reimer, Mauricio Rodriguez-Lanetty, Stephanie Rosalas, Osama S. Saad, Eugenia M. Sampayo, Scott Santos, Eiichi Shoguchi, Edward G. Smith, Michael Stat, Timothy G. Stephens, Marie E. Strader, David J. Suggett, Timothy D. Swain, Cawa Tran, Nikki Traylor-Knowles, Christian R. Voolstra, Mark E. Warner, Virginia M. Weis, Rachel Wright, Tingting Xiang, Hiroshi Yamashita, Maren Ziegler, Adrienne M.S. Correa, John Everett Parkinson

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: Symbiodinaceae; genetic diversity; coral symbiosis

Online: 21 June 2022 (04:49:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202206.0273.v1

The Heavy Mineral Map of Australia: Vision and Pilot Project

Patrice De Caritat, Brent I.A. McInnes, Alexander T. Walker, Evgeniy Bastrakov, Stephen M. Rowins, Alexander M. Prent

Subject: Environmental And Earth Sciences, Geochemistry And Petrology Keywords: heavy minerals atlas; heavy mineral maps; National Geochemical Survey of Australia; mineral network analysis; geological setting; mineral system; mineral prospectivity; critical minerals; critical elements

Online: 20 June 2022 (11:16:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202206.0151.v1

Research on Forecast and Suppression Splashing Method of AOD Furnace

Changjun Guan

Subject: Engineering, Control And Systems Engineering Keywords: Forecast splashing; suppression splashing; AOD; signal fusion; fuzzy control

Online: 10 June 2022 (07:51:53 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202206.0137.v1

FAIR Sharing of Reproducible Models of Epidemic and Pandemic Forecast

Kausthubh Ramachandran, Matthias König, Martin Scharm, Tung V. N. Nguyen, Henning Hermjakob, Dagmar Waltemath, Rahuman S. Malik Sheriff

Subject: Medicine And Pharmacology, Pulmonary And Respiratory Medicine Keywords: FAIR; epidemiology; models; pandemic forecast; SIR modelling; standards

Online: 9 June 2022 (07:55:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202206.0128.v1

Structural and Dynamical Properties of Liquid Water Increase Turbulent Flows

Arturo Tozzi, James Peters, Lucio Mariniello

Subject: Physical Sciences, Applied Physics Keywords: Reynold number; high-density water; molecular dynamics; water model; percolation theory

Online: 8 June 2022 (12:24:33 CEST)

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Preprint REVIEW | doi:10.20944/preprints202206.0114.v1

Metabolic Food Waste as Food Insecurity Factor – Causes and Preventions

Ioana Mihaela Balan, Emanuela Diana Gherman, Ioan Brad, Remus Gherman, Adina Horablaga, Teodor Ioan Trasca

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: food security; sustainable and healthy food choices/systems; metabolic food waste; nutrition; overconsumption

Online: 8 June 2022 (05:21:51 CEST)

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Preprint REVIEW | doi:10.20944/preprints202206.0072.v1

Tissue Cultured Regeneration and Ecological Values in Major Bamboo Species

Avinash Sharma, Chowlani Manpoong, Anweshy Gohain, Gompi Padu, Hage Aku

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: bamboo; tissue culture; growth regulators; hardening; carbon sequestration; climate

Online: 6 June 2022 (08:51:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202206.0052.v1

A Study of McVittie Spacetime in Stationary and Dynamical Regime

Indranath Bhattacharyya, Saibal Ray, Riju Nag, Samudra Sundar Nag

Subject: Physical Sciences, Astronomy And Astrophysics Keywords: Einstein equations; McVittie solution; black hole; dark energy; embedded spacetime

Online: 6 June 2022 (03:17:36 CEST)

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Preprint REVIEW | doi:10.20944/preprints202206.0046.v1

Epigenetic Modifications and Targeted Therapy in Pediatric Acute Myeloid Leukemia

Huan Xu, Yuxi Wen, Runming Jin, Hongbo Chen

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Acute myeloid leukemia; Pediatric; Epigenetics; DNA methylation; Histone modification; Non-coding RNAs; Therapy

Online: 3 June 2022 (10:59:28 CEST)

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Preprint REVIEW | doi:10.20944/preprints202206.0030.v1

New Insights into the Boron Essentiality on Humans and Animals

Andrei Bita, Ion Romulus Scorei, Tudor Adrian Balseanu, Maria Viorica Ciocilteu, Antonia Radu, George Dan Mogosanu, Steven A. Benner

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: naturally organic boron containing compounds; prebiotic candidate; microbiome; intestinal microflora; symbiosis

Online: 2 June 2022 (09:04:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202205.0401.v1

Optimization and Hydration Mechanism of Ecological Ternary Cements Containing Phosphogypsum

Jiaojiao Hou, Xiaoyang Ni, Baosong Ma

Subject: Engineering, Civil Engineering Keywords: ecological cement; cementitious system; thermodynamic; calcium silicate hydrate; tricalcium silicate; GEM-Selektor

Online: 30 May 2022 (11:41:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202205.0398.v1

A Survey and Evaluation Model for Generative Software Development (GSD)

Mohammad Reza Besharati

Subject: Computer Science And Mathematics, Information Systems Keywords: Generative Software Development; Code Generation; Complexty Space

Online: 30 May 2022 (11:32:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202205.0396.v1

Customizable Collagen Vitrigel Scaffolds and Preliminary Results in Corneal Engineering

María Dolores Montalvo-Parra, Wendy Ortega-Lara, Denise Loya-García, Andres Bustamante-Arias, Guillermo Isaac Guerrero-Ramírez, César E. Calzada-Rodríguez, Guiomar Farid Torres-Guerrero, Bestabé Hernández-Sedas, Italia Tatnaí Cárdenas-Rodríguez, Sergio E. Guevara-Quintanilla, Marcelo Salán-Flores, Miguel Angel Hernández-Delgado, Salvador Garza-González, Mayra G Gamboa-Quintanilla, Luis Guillermo Villagómez-Valdez, Judith Zavala, Jorge Eugenio Valdez-García

Subject: Chemistry And Materials Science, Biomaterials Keywords: scaffold; collagen vitrigel; tissue engineering; cornea; corneal endothelium

Online: 30 May 2022 (11:25:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202205.0369.v1

Carbamazepine Removal by Clay-Based Materials Using Adsorption and Photodegradation

Ilil Levakov, Yuval Shahar, Giora Rytwo

Subject: Environmental And Earth Sciences, Environmental Science Keywords: carbamazepine; adsorption; clay minerals; organoclays; advanced oxidation processes; photocatalysis; water reuse

Online: 27 May 2022 (04:42:22 CEST)

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Preprint REVIEW | doi:10.20944/preprints202205.0359.v1

Divergent Conceptualization of Embodied Emotions in English and Chinese Languages

Pin Zhou, Hugo Critchley, Yoko Nagai, Chao Wang

Subject: Social Sciences, Behavior Sciences Keywords: emotion；conceptualization；interoception；afferent；efferent

Online: 26 May 2022 (08:57:02 CEST)

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Empirical and theoretical advances in human neuroscience have led to a reappraisal of the relationships between mind, brain and body, the implications of which are particularly relevant to understanding emotions, which is revealed to be embodied owing to the facts that they are on the one hand primarily arise from the internal bodily states controlled by interoceptive system, on the other they give rise to physiological reactions and physical action evoked by autonomic nervous system. More specifically, when considering the ‘embodied mind’ (i.e., how mental processes are inescapably contextualized by their location within the body), the brain, instead of the ‘master’ of the body, is increasingly revealed to function as the ‘servant’, with its primary goal to maintain the body’s homeostatic integrity. This is achieved through the control of interoceptive information concerning body’s physiological state, initially as ‘simple’ organ-level homeostatic reflexes and then through higher-order coordination across organ-systems allowing ‘allostatic policies’ to predict and maintain future health of the integrated whole ‘biological-self’. In this context, motivational and emotional feelings arise from interoceptive signals that accompany (motivational and emotional) internally-directed physiological responses, and externally-directed behaviors. Emotion concepts are thus the categorized embodied outcomes of bidirectional brain-body interactions and may arguably be differentiated into afferent interoceptive processes, i.e., from body to brain, and efferent/autonomic processes, i.e., from brain to body. When comparing emotion words used in Chinese and English languages, afferent/interoceptive processes seem to dominate conceptualization of embodied emotions in Chinese, while the efferent processes feature more commonly in English. The presence of distinct conceptual systems relating to emotions may, according to the linguistic relativity hypothesis as well as the theory of constructed emotion, significantly shape the distinct values and ‘national character’ of Chinese and English–speaking cultures. Correspondingly, it is argued that, in the expression of affective traits, Chinese-speaking people are biased towards being more receptive, reflective and adaptive, whereas native English speakers may tend to be more reactive, proactive and interactive. These patterns also encompass functions historically ascribed to bodily organs by traditional Chinese and ancient Greek medicine.

Preprint ARTICLE | doi:10.20944/preprints202205.0307.v1

Simulating 3D Human Postural Stabilization in Vibration and Dynamic Driving

Mojtaba Mirakhorlo, Nick Kluft, Raj Desai, Marko Cvetković, Tugrul Irmak, Barys Shyrokau, Riender Happee

Subject: Engineering, Automotive Engineering Keywords: comfort; vibration; biomechanics; postural stabilization

Online: 23 May 2022 (12:14:30 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202112.0420.v3

Essential Terminology and Considerations for Validation of Non-targeted Methods

Kapil Nichani, Steffen Uhlig, Manfred Stoyke, Sabine Kemmlein, Franz Ulberth, Ilka Haase, Maik Döring, Stephan G. Walch, Petra Gowik

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: Non-targeted methods; method validation; food fraud; food authenticity; mass spectrometry; spectroscopy; NGS; NMR

Online: 23 May 2022 (11:10:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202205.0178.v1

The Entropic Potential of Events in Deterministic and Indeterministic Systems

Mark Zilberman

Subject: Physical Sciences, Thermodynamics Keywords: entropy; event; deterministic system; indeterministic system; entropic potential of an event

Online: 13 May 2022 (04:38:38 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202205.0159.v1

Characterization and In Vivo Toxicity Assay of Uncoated Silicon Nanoparticles

Konstantin V. Zolotarev, Anton N. Mikhailov, Valeriya I. Nakhod, Maxim A. Sanzhakov, Elena G. Tikhonova, Marina V. Mikhailova

Subject: Chemistry And Materials Science, Biomaterials Keywords: uncoated silicon nanoparticles; aggregation; in vivo toxicity; LC50 for Danio rerio larvae

Online: 12 May 2022 (07:39:46 CEST)

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Preprint REVIEW | doi:10.20944/preprints202205.0141.v1

Alterations of Mitochondrial Network by Cigarette and e-Cigarette Vaping

Manasa Kanithi, Sunil Junapudi, Syed Islamuddin Shah, Matta Reddy Alavala, Ghanim Ullah, Bojjibabu Chidipi

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Cigarette smoking; e-cigarette smoking; mitochondria; fusion; fission

Online: 10 May 2022 (12:54:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202205.0126.v1

Medical Education: Patients‘ Perspectives on Clinical Training and Informed Consent

Inês Gil Santos, Cristina Costa Santos, Ivone Duarte

Subject: Social Sciences, Education Keywords: medical education; medical ethics; autonomy; patients' perspectives

Online: 10 May 2022 (03:52:44 CEST)

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Preprint REVIEW | doi:10.20944/preprints202205.0004.v1

Adil Bahaj, Safae Lhazmir, Mounir Ghogho, Houda Benbrahim

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: COVID-19; Exploratory Search; Machine Learning; Document Retrieval

Online: 4 May 2022 (12:20:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202204.0280.v1

Phenomenological Potentials for the Refractory Metals Cr, Mo and W

Vassilis Pontikis, Gianguido Baldinozzi

Subject: Physical Sciences, Condensed Matter Physics Keywords: Chromium; Molybdenum; Tungstene; Empirical potentials; phonons; thermal properties

Online: 28 April 2022 (10:03:21 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202204.0176.v1

Series of Floor and Ceiling Function—Part II: Infinite Series

Dhairya Shah, Manoj Sahni, Ritu Sahni, Ernesto León-Castro, Maricruz Olazabal-Lugo

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: ceiling function; floor function; Fibonacci Number; Generalised Dirichlet series; Lerch - Zeta Function; Hurwitz - Zeta function; Polylogarithm; Riemann-Zeta function

Online: 19 April 2022 (06:03:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202204.0150.v1

Genetic interaction of Thm2 and Thm1 Shapes Postnatal Craniofacial Bone

Erin Bumann, Portia Hahn Leat, Henry Wang, Brittany Hufft-Martinez, Wei Wang, Pamela Tran

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: Ttc21a; Ttc21b; mouse knock-out; jaw; facial bone; viscerocranium; Hh signaling

Online: 16 April 2022 (03:36:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202110.0065.v2

Further Developing the Judicial System Utilizing Cloud, VOIP, and Videoconferencing

S. M. Nazmuz Sakib

Subject: Computer Science And Mathematics, Information Systems Keywords: access to justice; cost of justice; judicial system; videoconferencing; judicial information system; litigants; internet technologies

Online: 11 April 2022 (10:10:21 CEST)

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Preprint REVIEW | doi:10.20944/preprints202204.0055.v1

Activity-Dependent Induction of Younger Molecular, Cellular and Organism Phenotypes

Thomas Lissek

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: cell; biology; aging; medicine; transcription; activity; neurons; brain; immune system; muscle

Online: 7 April 2022 (04:24:23 CEST)

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Preprint REVIEW | doi:10.20944/preprints202203.0124.v2

Biochemistry and Molecular Basis of Intracellular Flavonoid Transport in Plants

Boas Pucker, Dirk Selmar

Subject: Biology And Life Sciences, Plant Sciences Keywords: anthocyanins; proanthocyanidins; flavonols; flavones; flavonoid transport; flavonoid biosynthesis; flavonoid accumulation; ligandin; MATE; ABCC

Online: 28 March 2022 (17:03:39 CEST)

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Preprint REVIEW | doi:10.20944/preprints202203.0343.v1

Enacting Economic Resilience: A Synthesis of Economic and Communication Frameworks

Timothy Betts, Patrice M Buzzanell

Subject: Business, Economics And Management, Economics Keywords: resilience; communication; systemic risk; systemic recovery

Online: 25 March 2022 (09:02:49 CET)

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Preprint ARTICLE | doi:10.20944/preprints202203.0327.v1

Memory Enhancement with Kynurenic Acid and its Mechanisms in Neurotransmission

Diána Martos, Bernadett Tuka, Masaru Tanaka, László Vécsei, Gyula Telegdy

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: tryptophan; kynurenine; kynurenic acid; passive avoidance; cognitive domain; memory; cognitive enhancer; neurotransmission; receptor blockers; translational

Online: 24 March 2022 (08:57:45 CET)

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Preprint REVIEW | doi:10.20944/preprints202203.0325.v1

Industry 4.0 and Marketing: Towards an Integrated Future Research Agenda

Albérico Travassos Rosário, Joana Carmo Dias

Subject: Business, Economics And Management, Business And Management Keywords: industry 4.0; marketing

Online: 24 March 2022 (07:54:11 CET)

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Preprint ARTICLE | doi:10.20944/preprints202111.0359.v2

On the Emergence of Spacetime and Matter from Model Sets

Marcelo Amaral, Fang Fang, Raymond Aschheim, Klee Irwin

Subject: Physical Sciences, Particle And Field Physics Keywords: Quantum Gravity; Problem of Time; Particle Physics; Emergence; Holographic Principle; Model Sets

Online: 23 March 2022 (09:26:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints202203.0258.v1

Artificial Intelligence and Online Hate Speech Moderation: A Risky Match?

Natalie Alkiviadou

Subject: Social Sciences, Law Keywords: hate speech; artificial intelligence; social media platforms; content moderation; freedom of expression; non-discrimination

Online: 17 March 2022 (15:26:41 CET)

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Preprint ARTICLE | doi:10.20944/preprints202203.0250.v1

Identification and Distribution of Human-Biting Ticks in Northwestern Spain

María Carmen Vieira Lista, Moncef Belhassen-García, María Belén Vicente Santiago, Javier Sánchez-Montejo, Carlos Pedroza Pérez, Lía Carolina Monsalve Arteaga, Zaida Herrador, Rufino del Álamo-Sanz, Agustin Benito, Julio David Soto López, Antonio Muro

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Tick bites; Ixodidae; epidemiology: emerging diseases; Spain

Online: 17 March 2022 (10:18:51 CET)

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Preprint ARTICLE | doi:10.20944/preprints202203.0214.v1

Explainable AI-based Alzheimer’s Prediction and Management Using Multimodal Data

Sobhana Jahan, Kazi Abu Taher, M Shamim Kaiser, Mufti Mahmud, Md. Sazzadur Rahman, A. S. M. Sanwar Hosen, In-Ho Ra

Subject: Engineering, Control And Systems Engineering Keywords: Machine learning; Dementia; Data-level fusion

Online: 15 March 2022 (12:31:40 CET)

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Preprint REVIEW | doi:10.20944/preprints202203.0138.v1

Sovateltide Mediated Endothelin B Receptors Agonism and Curbing Neurological Disorders

Amaresh K Ranjan, Anil Gulati

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Endothelins; Endothelin B Receptors; Endothelin A Receptors; Neurodegeneration; Neurovascular and Neurologic disorders

Online: 10 March 2022 (03:58:53 CET)

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Preprint ARTICLE | doi:10.20944/preprints202203.0065.v1

Dielectric Properties of Aqueous Solutions at Normal and High Dilutions

Sergey Vladimirovich Savel’ev, Ludmila Arkad’evna Morozova

Subject: Physical Sciences, Fluids And Plasmas Physics Keywords: radiothermal signals; radiobrightness temperature; normal and high dilution solutions; absorption coefficient; ion hydration shell; new dielectric properties; supramolecular interactions; dispersion

Online: 3 March 2022 (13:52:45 CET)

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Preprint ARTICLE | doi:10.20944/preprints202203.0056.v1

Aerodynamic Performance and Wake Flow of Crosswind Kite Power Systems

Mojtaba Kheiri, Samson Victor, Sina Rangriz, Mher Marc Karakouzian, Frederic Bourgault

Subject: Engineering, Mechanical Engineering Keywords: Airborne wind energy; crosswind kite; induction factor; wake model; aerodynamic performance; CFD; analytical model

Online: 3 March 2022 (07:50:24 CET)

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Preprint ARTICLE | doi:10.20944/preprints202203.0054.v1

Robust PVC Identification by Fusing Expert System and Deep Learning

Zhipeng Cai, Tiantian Wang, Yumin Shen, Yantao Xing, Ruqiang Yan, Jianqing Li, Chengyu Liu

Subject: Engineering, Bioengineering Keywords: electrocardiogram; K-means clustering algorithm; premature ventricular contraction; rule-based decision algorithm

Online: 3 March 2022 (07:22:36 CET)

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Preprint ARTICLE | doi:10.20944/preprints202203.0045.v1

Morphotectonic and Petrological Characteristics of Permo-Triassic Traps of Siberia

Victor Sharapov, Yury Perepechko, Anna Mikheeva, Igor Ashchepkov, Viktoria Lyamina, Anatoly Boguslavsky

Subject: Environmental And Earth Sciences, Geochemistry And Petrology Keywords: Siberian traps; petrology; morphotectonics; GIS technologies

Online: 2 March 2022 (10:58:52 CET)

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Preprint ARTICLE | doi:10.20944/preprints202112.0340.v2

Spin g Factors and Neutrino Magnetic Moment of Elementary Fermions

Jae-Kwang Hwang

Subject: Physical Sciences, Particle And Field Physics Keywords: Anomalous spin g factor; Lepton charge (LC); Neutrino magnetic moment; Weak force decay; EC and LC partial masses; Three-dimensional quantized space model (TQSM)

Online: 1 March 2022 (11:25:10 CET)

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Preprint ARTICLE | doi:10.20944/preprints202203.0001.v1

Curcumin and Ethanol Effects in Trembler-J Schwann Cell Culture

Lucia Vázquez Alberdi, Gonzalo Rosso, Lucía Velóz, Carlos Romeo, Joaquina Farias, María Vittoria Di Tomaso, Miguel Calero, Alejandra Kun

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: CMT1E; Trembler-J; curcumin; Hsps; autophagy; mTOR

Online: 1 March 2022 (02:52:34 CET)

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Charcot-Marie-Tooth (CMT) syndrome is the most common progressive human motor and sensory peripheral neuropathy. CMT type 1E is a demyelinating neuropathy affecting Schwann cells due to pmp22 mutations, modelized by Trembler-J mice. Curcumin, a natural polyphenol com-pound obtained from turmeric (Curcuma longa), exhibits dose- and time-varying antitumor, antioxidant and neuroprotective properties, however, the neurotherapeutic actions of curcumin still remain elusive. Here, we propose curcumin as a possible natural treatment capable of enhancing cellular detoxification mechanisms, resulting in an improvement of the neurodegenerative Trembler-J phenotype. Using a refined method for obtaining enriched Schwann cell cultures, we evaluated the neurotherapeutic action of low dose curcumin treatment on the PMP22 expression, and on the chaperones (HSF1 and Hsp27) and autophagy/mTOR (HDAC6 and ribosomes) pathways in Trembler-J and wild-type genotypes. In wild-type Schwann cells, the action of cur-cumin resulted in strong stimulation of the chaperone and macroautophagy pathway, whereas the modulation of ribophagy showed a mild effect. However, despite the promising neuroprotective effects for the treatment of neurological diseases, we report (demonstrate?) that the action of cur-cumin in Trembler-J Schwann cells could be impaired due to the irreversible impact of ethanol used as a common curcumin vehicle necessary for administration. These results contribute to expand our still limited understanding of PMP22 biology in neurobiology, and expose the intrinsic lability of the neurodegenerative Trembler-J genotype. Furthermore, they unravel interesting physiological mechanisms of cellular resilience relevant for to the pharmacological treatment of the neurodegenerative Tremble J phenotype with curcumin and ethanol. We conclude that the analysis of the effects of the vehicle itself is an essential and in-escapable step to comprehensibly assess the own effects and full potential of curcumin treatment for therapeutic purposes.

Preprint ARTICLE | doi:10.20944/preprints202202.0254.v1

Resolution Limit in Statistical Independence and Bayesian Network Scoring Functions

Grigoriy Gogoshin, Andrei Rodin

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: Bayesian networks; probabilistic networks; conditional independence; MDL; BIC; information-theoretic entropy

Online: 21 February 2022 (14:13:26 CET)

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Preprint ARTICLE | doi:10.20944/preprints202202.0229.v1

The Scale Invariant Vacuum Paradigm: Main Results and Current Progress

Vesselin Gueorguiev, Andre Maeder

Subject: Physical Sciences, Astronomy And Astrophysics Keywords: cosmology: theory - dark matter - dark energy - inflation; galaxies: formation - rotation; Weyl Integrable Geometry; Dirac co-calculus

Online: 18 February 2022 (09:22:34 CET)

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Preprint REVIEW | doi:10.20944/preprints202202.0213.v1

A Review on Multiscale Modelling and Simulation for Polymer Nanocomposites

Annu Sharma, Mamta Devi

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: Polymer nanocomposite; Multiscale modelling; Nanostructure; Nanoparticle; Interface; Simulation

Online: 17 February 2022 (11:51:28 CET)

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Preprint ARTICLE | doi:10.20944/preprints202202.0185.v1

Unauthorized Unmanned Aerial Vehicle Detection using YOLOv5 and Transfer Learning

Nader Al-Qubaydhi, Abdulrahman Alenezi, Turki Alanazi, Abdulrahman Senyor, Naif Alanezi, Bandar Alotaibi, Munif Alotaibi, Abdelaziz A. Abdelhamid, Abdul Razaque, Aziz Alotaibi

Subject: Engineering, Electrical And Electronic Engineering Keywords: drone detection; YOLOv5; unmanned aerial vehicle; deep learning

Online: 15 February 2022 (09:32:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints202202.0077.v1

Genetics of Externalizing Behavior and Structural Brain Development in Adolescence

Jalmar Teeuw, Marieke Klein, Nina Roth Mota, Rachel M. Brouwer, Dennis van 't Ent, Zyneb Al-Hassaan, Barbara Franke, Dorret I. Boomsma, Hilleke E. Hulshoff Pol

Subject: Social Sciences, Behavior Sciences Keywords: externalizing behavior; adolescence; gray matter volume; white matter integrity; heritability; genetic correlation; longitudinal; magnetic resonance imaging

Online: 4 February 2022 (15:07:45 CET)

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Preprint REVIEW | doi:10.20944/preprints202202.0050.v1

Neural Implants: A Review Of Current Trends And Future Perspectives

Halima-Tul-Rokeya Mim, Munima Haque, Salman Khan Promon

Subject: Engineering, Bioengineering Keywords: Neuroprosthetics; Brain Computer Interface; Neural Implants; Deep Brain Stimulation

Online: 3 February 2022 (11:06:15 CET)

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Preprint REVIEW | doi:10.20944/preprints202202.0031.v1

Origin and Early Evolution of Photosynthesis: A Brief Historical Account

Tanai Cardona

Subject: Biology And Life Sciences, Life Sciences Keywords: photosynthesis; photosystem; water oxidation; oxygenic; evolution; origin of life

Online: 2 February 2022 (12:17:37 CET)

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Preprint REVIEW | doi:10.20944/preprints202202.0022.v1

T Lymphocyte-Derived Exosomes and Their Applications in Cancer Therapy

Victor Calvo, Manuel Izquierdo

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: exosomes; T lymphocytes; immune synapse; secretory granules; multivesicular bodies; cytotoxic activity; cell death; CAR T lymphocytes

Online: 1 February 2022 (21:33:57 CET)

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Preprint ARTICLE | doi:10.20944/preprints202202.0015.v1

MRI-GAN: MRI and Tissues Transfer Using Generative Adversarial Networks

Afifa Khaled

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Deep learning; Machine learning

Online: 1 February 2022 (13:34:28 CET)

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Preprint ARTICLE | doi:10.20944/preprints202201.0469.v1

Smartphone-Guided Educational Counseling and Self-Help for Chronic Tinnitus

Winfried Schlee, Patrick Neff, Jorge Simoes, Berthold Langguth, Stefan Schoisswohl, Heidi Steinberger, Marie Norman, Myra Spiliopoulou, Johannes Schobel, Ronny Hannemann, Rüdiger Pryss

Subject: Social Sciences, Psychology Keywords: tinnitus; self-help; ecological momentary assessment; ehealth; smart-phone; intervention

Online: 31 January 2022 (14:00:09 CET)

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Preprint ARTICLE | doi:10.20944/preprints202103.0326.v2

Displacement Formulations for Deformation and Vibration of Elastic Circular Torus

Bohua Sun

Subject: Physical Sciences, Acoustics Keywords: circular torus; deformation; vibration; Gauss curvature; Maple

Online: 25 January 2022 (10:04:29 CET)

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Preprint TECHNICAL NOTE | doi:10.20944/preprints202201.0353.v1

GXP: Analyze and Plot Plant Omics Data in Web Browsers

Constantin Eiteneuer, David Velasco, Joseph Atemia, Dan Wang, Andrea Schrader, Roland Pieruschka, Sven Fahrner, Rainer Schwacke, Vanessa Wahl, Ulrich Schurr, Björn Usadel, Asis Hallab

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: RNA sequencing; metabolomics; data visualization; overrepresentation analysis; cluster analysis; principal component analysis; scientific plotting; Mapman; Mercator

Online: 24 January 2022 (12:36:04 CET)

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Preprint ARTICLE | doi:10.20944/preprints202104.0762.v3

Uncertainty Quantification And Sensitivity Analysis Of Parameterization-free Surrogate Model

Jiajun Cao, Qingbiao Li, Liping Xu, Rui Yang, Yuejin Dai

Subject: Engineering, Mechanical Engineering Keywords: uncertainty quantification; sensitivity analysis; surrogate model method; optimisation; graph neural network; parameterisation

Online: 24 January 2022 (10:39:52 CET)

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Preprint REVIEW | doi:10.20944/preprints202201.0241.v1

Diabetes Mellitus: A path to Amnesia, Personality and Behavior Change.

Rahnuma Ahmad, Kona Chowdhury, Santosh Kumar, Mohammed Irfan, Govindool Sharaschandra Reddy, Farhana Akter, Dilshad Jahan, Mainul Haque

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Diabetes Mellitus; Vascular Dementia; Alzheimer’s Disease; Inflammation; Atherosclerosis; Mitochondrial dysfunction; Cognitive dysfunction

Online: 17 January 2022 (15:46:10 CET)

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Preprint REVIEW | doi:10.20944/preprints202201.0231.v1

Multiscale Modelling of Fuel Cells and Related Energy Conversion Systems

Ilenia Rossetti

Subject: Engineering, Energy And Fuel Technology Keywords: Fuel cells modelling; Heat and power cogeneration; PEMFC; SOFC

Online: 17 January 2022 (14:13:45 CET)

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Preprint ARTICLE | doi:10.20944/preprints202107.0322.v3

Thermal Fluctuations and Electromagnetic Noise Spectra in Quantum Statistical Mechanics

Ladislaus Alexander Bányai, Mircea Bundaru, Paul Gartner

Subject: Physical Sciences, Condensed Matter Physics Keywords: fluctuations; noise spectra; longitudinal and transverse electric fields; Nyquist noise; photon number noise

Online: 17 January 2022 (09:04:34 CET)

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Preprint REVIEW | doi:10.20944/preprints202110.0258.v2

Recent Progress on Methods for Estimating and Updating Large Phylogenies

Paul Zaharias, Tandy Warnow

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: phylogeny estimation; multiple sequence alignment; phylogenetic placement; phylogenomics; taxon identification; maximum likelihood

Online: 12 January 2022 (18:56:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints202201.0111.v1

Beam Damage Assessment Using Natural Frequency Shift and Machine Learning

Nicoleta Gillich, Cristian Tufisi, Christian Sacarea, Catalin V Rusu, Gilbert-Rainer Gillich, Zeno-Iosif Praisach, Mario Ardeljan

Subject: Engineering, Mechanical Engineering Keywords: damage detection; linear regression; random forest; artificial neural network; training parameters; natural frequency

Online: 10 January 2022 (12:26:27 CET)

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Preprint ARTICLE | doi:10.20944/preprints202201.0109.v1

Carbon Dots/Iron Oxide Nanoparticles With Tuneable Composition and Properties

Joanna D Stachowska, Monika B Gamża, Claire Mellor, Ella N Gibbons, Marta J Krysmann, Antonios Kelarakis, Elżbieta Gumieniczek-Chłopek, Tomasz Strączek, Czesław Kapusta, Anna Szwajca

Subject: Chemistry And Materials Science, Nanotechnology Keywords: magnetization; photoluminescence; carbon dots; magnetic nanoparticles; antimicrobial

Online: 10 January 2022 (12:21:24 CET)

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Preprint REVIEW | doi:10.20944/preprints202201.0102.v1

Normal and Neoplastic Growth Suppression by The Extended Myc Network

Huabo Wang, Edward Prochownik

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: ChREBP; L-Myc; Max; Mga; Mlx; Mnt; MondoA; Mxd; N-Myc; tumor suppressor

Online: 10 January 2022 (12:01:35 CET)

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Preprint ARTICLE | doi:10.20944/preprints202201.0094.v1

A BIM Based Framework for Damage Segmentation, Storage, and Visualization

Mathias Artus, Mohamed Alabassy, Christian Koch

Subject: Engineering, Civil Engineering Keywords: Building Information Modeling; defects; damage information modeling; life cycle; bridges; inspection; maintenance

Online: 6 January 2022 (17:45:29 CET)

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Preprint ARTICLE | doi:10.20944/preprints202201.0056.v1

Electrospun ZnSnO₃/ZnO Composite Nanofibers and Its Air-Sensitive Properties

Songtao Dong, Xiaoyun Jin, Junlin Wei, Hongyan Wu

Subject: Chemistry And Materials Science, Nanotechnology Keywords: Electrospinning; ZnSnO3/ZnO nanofibers; Sensing performance; n-n heterojunction

Online: 6 January 2022 (09:51:23 CET)

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