ARTICLE
|
doi:10.20944/preprints202207.0358.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Foot-and-mouth disease virus; safe sample transport; single-stranded positive-sense RNA; TRIzol extraction; naked RNA; infectivity; RNA transfection; lipofectamine; self-transfection; BHK cells
Online: 25 July 2022 (08:14:51 CEST)
REVIEW
|
doi:10.20944/preprints202110.0016.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
prostate cancer; castrate-resistant growth; metastases; androgen receptor; glucocorticoid receptor; cytokines; transmembrane receptors; cell signaling; pharmacological targeting; neuroendocrine differentiation; lineage plasticity; prostate cancer stem cells
Online: 1 October 2021 (12:19:03 CEST)
ARTICLE
|
doi:10.20944/preprints202108.0202.v1
Subject:
Medicine And Pharmacology,
Surgery
Keywords:
congenital breast asymmetry; PROM, autologous fat injections, fat grafting, lipograft, implant augmentation, breast augmentation, 3D volumetry, three-dimensional imaging, Breast-QTM; human adipose stem cells
Online: 9 August 2021 (15:06:09 CEST)
REVIEW
|
doi:10.20944/preprints202106.0337.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
alcohol use disorders (AUD); cancer, ethanol oxidative and nonoxidative metabolism, acetaldehyde, reactive oxygen species (ROS), DNA adducts, protein damage, cancer stem cells (CSC), epigenetic changes.
Online: 14 June 2021 (09:03:43 CEST)
ARTICLE
|
doi:10.20944/preprints201912.0133.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
advanced glycation end products (ages); drought; glycation; sh-sy5y human neuroblastoma cells; metabolomics; osmotic stress; pea (pisum sativum l.); pro-inflammatory; seeds; seed metabolism; signaling
Online: 10 December 2019 (14:53:42 CET)
REVIEW
|
doi:10.20944/preprints201908.0234.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
osteoarthritis; articular cartilage; degeneration; regeneration; therapeutic protein; growth factor; protein production platform; protein packaging cell line; transforming growth factor β (TGF-β); GP2-293 cells
Online: 23 August 2019 (03:33:49 CEST)
REVIEW
|
doi:10.20944/preprints202101.0304.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Vascular Endothelial Growth Factors (VEGFs); VEGF-A; PlGF; VEGF-B; VEGF-C; VEGF-D; angiogenesis; lymphangiogenesis; CCBE1; proteases; ADAMTS3; plasmin; cathepsin D; KLK3; prostate-specific antigen (PSA); thrombin; wound healing; metastasis; proteolytic activation; vascular biology
Online: 18 January 2021 (09:05:58 CET)
REVIEW
|
doi:10.20944/preprints201811.0378.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
viral entry; viral glycoproteins; virus receptors; UL148; US16; UL128-131; gB; gO; PDGFRα; integrins; Nrp2; gH/gL; cytomegalovirus; herpesviruses; HCMV; CMV; pentamer; trimer; glycoprotein H; glycoprotein L; glycoprotein O; glycoprotein B; UL128; UL130; UL131A; UL131
Online: 16 November 2018 (06:52:54 CET)
ARTICLE
|
doi:10.20944/preprints201707.0033.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
hepatic inflammation; high-fat-cholesterol diet; hypertension; mitogen-activated protein kinase; nonalcoholic steatohepatitis; nuclear factor erythroid 2-related factor 2 pathway; nuclear factor-kappa B; spontaneously hypertensive rat; stroke-prone spontaneously hypertensive5/Dmcr; Wistar Kyoto
Online: 14 July 2017 (10:54:38 CEST)
ARTICLE
|
doi:10.20944/preprints202405.1511.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Breast cancer; network pharmacology; text mining; drug therapy; genes; pathway analysis; biological process; protein-protein interaction; degree and betweenness; molecular docking; meristematic cells; anti-mitotic; hepatotoxicity
Online: 23 May 2024 (07:34:57 CEST)
ARTICLE
|
doi:10.20944/preprints202402.1524.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Coccomyxa subellipsoidea KJ; metallothioneins; Th17 cytokines; T cell activation; immunoregulation; transcriptome analysis; peripheral blood mononuclear cells; inflammatory factors; toxic shock syndrome toxin-1; immune regulatory drugs
Online: 27 February 2024 (10:26:51 CET)
REVIEW
|
doi:10.20944/preprints202306.0833.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Cancer-testis-antigens; parthenogenetic; polyploid giant cancer cells; PGCCs; genome fragility; phylostratigraphic analysis; innate immunity-placentation; endogenous retroviruses; sex determination; male infertility; endocrine disruption; environmental pollution
Online: 12 June 2023 (12:59:23 CEST)
REVIEW
|
doi:10.20944/preprints201809.0217.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Premature ovarian insufficiency, POI; Gene therapy; Menopause; SAL-like 4 genes, SALL4; Follicle-stimulating hormone (FSH); Basonuclin-1; Replication-incompetent adenoviral vector, Ad; Stem cells, SC.
Online: 12 September 2018 (11:06:42 CEST)
REVIEW
|
doi:10.20944/preprints202209.0482.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Telomerase reverse transcriptase; TERT; TERT promoter; TERTp; human papillomavirus; HPV; Epstein Barr virus (EBV); Kaposi sarcoma-associated herpesvirus; HHV-8; hepatitis B virus; HBV; hepatitis C virus; HCV; human T-cell leukemia virus-1; HTLV-1
Online: 30 September 2022 (10:11:58 CEST)
REVIEW
|
doi:10.20944/preprints202406.0771.v1
Subject:
Medicine And Pharmacology,
Otolaryngology
Keywords:
anti-cancer therapy; carcinogenesis; cell plasticity; chemoresistance; head and neck cancer (HNC); head and neck squamous cell carcinoma (HNSCC); mesenchymal stromal cells (MSCs); tumour niche; tumour environment
Online: 12 June 2024 (14:44:09 CEST)
ARTICLE
|
doi:10.20944/preprints202305.0700.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
allogeneic hematopoietic stem cell transplantation; autoimmune limbic encephalitis; cyclo-phosphamide; regulatory T cells; CD25; Foxp3; IL-6; fever; acute graft-versus-host disease; cyto-kine-release syndrome
Online: 10 May 2023 (07:46:24 CEST)
ARTICLE
|
doi:10.20944/preprints202107.0484.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
metformin; Natural Killer cells; Cytotoxic T lymphocytes; intercellular adhesion molecule-1 (ICAM-1); Natural Killer G2-D (NKG2D) ligands (NKG2DL); lymphocyte function-associated antigen 1 (LFA-1)
Online: 21 July 2021 (10:54:14 CEST)
REVIEW
|
doi:10.20944/preprints202007.0674.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
osteoarthritis; articular cartilage; degeneration; regeneration; therapeutic protein; growth factor; protein production platform; protein packaging cell line; transforming growth factor β (TGF-β); GP2-293 cells; TissueGene-C
Online: 28 July 2020 (10:16:51 CEST)
REVIEW
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Neuroendocrine Neoplasms; NOTCH; cancer driven genes; mutational mechanism; germline mutations.; small cell lung carcinoma; pancreatic NET; small bowel NET; medullary thyroid carcinoma; malignant castration-resistant prostatic cells
Online: 23 July 2019 (10:34:50 CEST)
ARTICLE
|
doi:10.20944/preprints201807.0317.v3
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Boswellia serrata Roxb.; Curcuma longa L.; intestinal bowel diseases (IBD); Caco-2; PBMC; HMC-1.1; mast cells; cytokines; trans epithelial electrical resistance (TEER); reactive oxygen species (ROS)
Online: 8 November 2018 (04:53:46 CET)
DATA DESCRIPTOR
|
doi:10.20944/preprints202312.0561.v1
Subject:
Biology And Life Sciences,
Forestry
Keywords:
Pinus sylvestris L.; Scots pine; seed spectrometric feature; individual seed; container-growm germination; RGB color space; L*a*b* color space; seed size; individual seed mass; Dickson quality index (DQI); forest landscape restoration (FLR)
Online: 8 December 2023 (05:47:28 CET)
ARTICLE
|
doi:10.20944/preprints202311.1694.v1
Subject:
Engineering,
Electrical And Electronic Engineering
Keywords:
Cu-(In,Ga)-Se2 (CIGSe) solar cells; Two-segment process; Metal-alloy compositions; Internal/External quantum efficiencies (IQE/EQE); Sustainable development goal; Eco-friendly community
Online: 27 November 2023 (11:51:53 CET)
ARTICLE
|
doi:10.20944/preprints202208.0324.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
T cytotoxic cells; Leukocyte-associated Immunoglobulin-like Receptor-1; LAIR-1; Hepatitis C virus genotype 4; HCV G4; hepatocellular carcinoma; cirrhosis; immune inhibitory checkpoints; inflammation; prognosis; insulin resistance
Online: 17 August 2022 (11:38:10 CEST)
ARTICLE
|
doi:10.20944/preprints202312.2191.v1
Subject:
Physical Sciences,
Mathematical Physics
Keywords:
r+1Rs,k(B, C, z) matrix function; k-fractional integral operators; k-fractional derivative operators; Riemann-Liouville k-fractional integral; k-Gamma matrix function; k-Beta matrix function
Online: 28 December 2023 (15:17:30 CET)
ARTICLE
|
doi:10.20944/preprints202304.0625.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
adverse drug reaction; cisplatin liposomes; circulating tumor cells; enhanced permeability and retention effect; nephrotoxicity; pulmonary metastasis of pancreatic cancer; quality of life; recurrent liver metastases from primary nasal cancer
Online: 20 April 2023 (07:52:10 CEST)
ARTICLE
|
doi:10.20944/preprints202211.0080.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Tumor initiation; Germ cell traits of tumors; Primordial germ cell-like tumor cells; Somatic to Pri-mordial germ cell-like transformation; Embryonic/germ cell hypothesis of tumor; Breast cancer
Online: 4 November 2022 (01:04:58 CET)
ARTICLE
|
doi:10.20944/preprints202403.1569.v1
Subject:
Computer Science And Mathematics,
Computer Science
Keywords:
Random boolean networks; entropy; algorithmic complexity; compressibility
Online: 26 March 2024 (10:07:13 CET)
REVIEW
|
doi:10.20944/preprints202402.0456.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
Keywords: keyword triggering receptor expressed in myeloid cells-like transcript (TLT-1); blood platelets; cardiovascular diseases; left ventricular ejection fraction (LVEF); biomarker; anthracyclines, Troponin I, cardiotoxicity, congestive heart failure (CHF)
Online: 7 February 2024 (17:08:39 CET)
HYPOTHESIS
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
environment; virus; pollutant; evolution; exaptation; stem cells; transposons; APOBEC; ADAR,; ORF2p; cancer; Eco-Evo-Devo; symbiosis; ecological genomics; environmental stress; genetic recombination; biological plasticity; hypermutation; epigenetics; fractal systems; natural selection
Online: 19 July 2020 (19:35:46 CEST)
ARTICLE
|
doi:10.20944/preprints201901.0245.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
Osteomeles Schwerinae; diabetic retinopathy (DR); spontaneously diabetic Torii (SDT) rat; human retinal microvascular endothelial cells (HRMECs); advanced glycation end products (AGEs); retinal apoptosis; oxidative stress; mitochondrial function; adjunctive effect; combination therapy
Online: 24 January 2019 (08:37:29 CET)
HYPOTHESIS
|
doi:10.20944/preprints202109.0372.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Endometriosis; microchimerism; maternal microchimerism; reproduction; gynaecology; etiology; auto-immune; immune response; hormonal; vascular; genetic; hereditary; male; fetal; fetus; stem cells; pregnancy; Műllerianosis; embryology; ROS; apoptosis; disease; endometrium; basalis; menstruation; post-menopausal; neurogenesis
Online: 22 September 2021 (10:27:52 CEST)
ARTICLE
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
protein/rna world; plasma membrane; cytoplasm; virus world; pre-retro virus; emergence of dna; transcription and replication; first cells; hyperthermophiles; luca; bacteria and archaea; anoxygenic bacteria; oxygenic bacteria; global distribution of cyanobacteria
Online: 15 October 2019 (11:18:58 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0122.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Tissue agnostic drug development; Pembrolizumab; Microsatellite instability-high (MSI-H); Tumor mutational burden-high (TMB-H); Dostarlimab-gxly; Larotrectinib; Entrectinib; Neurotrophic tyrosine kinase (NTRK); Dabrafenib and trametinib; V-Raf Murine Sarcoma Viral Oncogene Homolog B V600E (BRAFV600E); Selpercatinib; Rearranged during transfection (RET); Precision oncology.
Online: 3 June 2024 (16:08:38 CEST)
REVIEW
|
doi:10.20944/preprints202403.1200.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Mast cells; Sentinel cell; Health; Ovulation; Pregnancy; Inflammation; Wound healing; Cell prolif-eration; Angiogenesis; bFGF; VEGF-A; Tissue remodeling; Histamine; Serotonin; Heparin; Proteases; IL-1-alpha; IL-8; TNF-alpha; Nitric oxide; Survival; Progeny
Online: 20 March 2024 (09:50:02 CET)
ARTICLE
Subject:
Environmental And Earth Sciences,
Paleontology
Keywords:
protein/RNA world: plasma membrane; cytoplasm; gene regulation; virus world; pre-retro virus; emergence of DNA; transcription and replication; first cells; hyperthermophiles; LUCA; Bacteria and Archaea; anoxygenic bacteria; oxygenic bacteria; global distribution of cyanobacteria
Online: 12 February 2020 (03:25:07 CET)
ARTICLE
|
doi:10.20944/preprints202309.1265.v1
Subject:
Engineering,
Other
Keywords:
Multijunction solar cells; IIIV semiconductors; TCAD simulation; cell optimization; predictive profiling; CIGS absorbers; spectral utilization; currentvoltage characteristics; external quantum efficiency; GaAs replacement; bottom junction; thin films; high efficiency; photovoltaics; epitaxial growth; stacked junctions; light absorption
Online: 19 September 2023 (07:48:35 CEST)
REVIEW
Subject:
Medicine And Pharmacology,
Psychiatry And Mental Health
Keywords:
multiple sclerosis; MS; cause; genes; polygenic; heredity; autoimmune; diet; depression; fatigue; suicide; seizures; bowel disorders; thyroid; mitochondria; chromosome 2; chromosome 5; glial cells; sunlight; vitamin D3; ultraviolet radiation; melanocyte stimulating hormone; melanocyte concentrating hormone; stress
Online: 22 July 2019 (04:37:27 CEST)
ARTICLE
|
doi:10.20944/preprints201810.0088.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
There are many molecules used as drug carrier. TUD-1 is a newly synthesized mesoporous silica (SM) molecule possess two important features; consists of mesoporous so it is very suitable to be drug carrier in addition to that it has the ability to induce apoptosis in cancer cells. However, the effect of TUD-1 appears to act as cell death inducer, regardless of whether it is necrosis or apoptosis. Unfortunately, recent studies indicate that a proportion of cells undergo necrosis rather than apoptosis, which limits the use of TUD-1 as a secure treatment. On the other hand, lithium considered as necrosis inhibitor element. Hence, current study based on the idea of production a new Li/TUD-1 by incorporated mesoporous silica (TUD-1 type) with lithium in order to produce a new compound that has the ability to activate apoptosis by mesoporous silica (TUD-1 type) and at the same time can inhibit the activity of necrosis by lithium. Herein, lithium was incorporated in TUD-1 mesoporous silica by
Online: 4 October 2018 (15:54:02 CEST)
REVIEW
|
doi:10.20944/preprints202303.0500.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
Oxidative stress and cell death; Reactive oxygen species; ROS; ROS cell death; autophagy; role of antioxidants; eye disease; cornea; lens; epithelium; retinal ganglion cells; retinal pigment epithelium; macular degeneration; antioxidants in the macula; oxidative stress prevention with antioxidants; lifestyle changes; digital eye strain; glaucoma; cataracts; dry eye disease; computer vision syndrome; digital eye strain; diabetic retinopathy; Vitamin A; Vitamin C; copper; glutathione; zinc; selenium; magnesium; blue light damage; UV light damage; blue light reactive oxygen species; autophagy; ferroptosis; ROS cell death; superoxide dismutase; optic nerve gliomas; food deserts; myopia; free radicals
Online: 29 March 2023 (03:33:55 CEST)