ARTICLE
|
doi:10.20944/preprints202405.0395.v1
Subject:
Physical Sciences,
Biophysics
Keywords:
Individual molecule tracking; diffusion; thermodynamic jitter; live cell, cytoplasm, liquids, room temperature, continuous-time random walk (CTRW); Brownian motion/diffusion anomalous motion/diffusion; computer simulations
Online: 7 May 2024 (13:08:33 CEST)
REVIEW
|
doi:10.20944/preprints202312.0717.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Cancer immunotherapy 1; Resistance 2; Tumor microenvironment 3; Combination therapies 4; Immune checkpoint targets 5; Adoptive cell therapies 6; Cancer vaccines 7; Personalized medicine 8.
Online: 11 December 2023 (17:53:38 CET)
ARTICLE
|
doi:10.20944/preprints202311.1139.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
non-small cell lung cancer; ionizing radiation; DNA repair; PrimPol; DNA damage tolerance; translesion synthesis; Pol iota (Polι ); clonogenic survival; cancer stem-like cells
Online: 17 November 2023 (07:47:41 CET)
ARTICLE
|
doi:10.20944/preprints202304.0251.v1
Subject:
Physical Sciences,
Atomic And Molecular Physics
Keywords:
radioactive atomic beams; gas stopping cell; supersonic gas jet; in-gas-jet laser resonance ionization spectroscopy; double-nozzle technique; gas dynamic and Monte Carlo simulations
Online: 12 April 2023 (07:30:00 CEST)
ARTICLE
|
doi:10.20944/preprints202209.0160.v1
Subject:
Engineering,
Mechanical Engineering
Keywords:
Strain gauge load cell; machine design; axial force measurement; force test bench; shape optimiza-tion; finite element method (FEM); Wheatstone bridge; amplifier circuit; calibration test
Online: 13 September 2022 (05:47:32 CEST)
REVIEW
|
doi:10.20944/preprints202110.0016.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
prostate cancer; castrate-resistant growth; metastases; androgen receptor; glucocorticoid receptor; cytokines; transmembrane receptors; cell signaling; pharmacological targeting; neuroendocrine differentiation; lineage plasticity; prostate cancer stem cells
Online: 1 October 2021 (12:19:03 CEST)
REVIEW
|
doi:10.20944/preprints202103.0373.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Mesenchymal stem/stromal cells; regenerative medicine; tissue engineering; Clinical Application; Differentiation Capacity; Cellular Immunomodulation; Inflammation; Signaling Cells; Transplantation; International Society for Cell and Gene Therapy
Online: 15 March 2021 (11:51:28 CET)
REVIEW
|
doi:10.20944/preprints201908.0234.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
osteoarthritis; articular cartilage; degeneration; regeneration; therapeutic protein; growth factor; protein production platform; protein packaging cell line; transforming growth factor β (TGF-β); GP2-293 cells
Online: 23 August 2019 (03:33:49 CEST)
ARTICLE
|
doi:10.20944/preprints202304.0880.v1
Subject:
Engineering,
Electrical And Electronic Engineering
Keywords:
Driver Jetson Nano; Drowsiness Detection; Object Detection (Cigarette & Cell Phone); OpenCV; You Look Only Once (YOLO) Algorithm; Air Fuel Ratio; Engine Control Unit (ECU); Speed Control
Online: 25 April 2023 (03:59:34 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0648.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
herpes simplex virus type 1 (HSV-1); bovine herpesvirus 1 (BoHV-1); Krüppel–like factor 15 (KLF15); infected cell protein 0 (ICP0); BoHV-1 ICP0 (bICP0)
Online: 26 May 2021 (15:10:59 CEST)
ARTICLE
|
doi:10.20944/preprints202012.0312.v1
Subject:
Engineering,
Automotive Engineering
Keywords:
Bayesian Network; Root Cause Analysis; Failure Mode and Effect Analysis; Lithium-Ion 15 Battery Cell; Failure Propagation; Multi-Stage Production; Manufacturing Process; Process Optimization; Scrap Rate
Online: 14 December 2020 (09:31:30 CET)
REVIEW
|
doi:10.20944/preprints202303.0500.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
Oxidative stress and cell death; Reactive oxygen species; ROS; ROS cell death; autophagy; role of antioxidants; eye disease; cornea; lens; epithelium; retinal ganglion cells; retinal pigment epithelium; macular degeneration; antioxidants in the macula; oxidative stress prevention with antioxidants; lifestyle changes; digital eye strain; glaucoma; cataracts; dry eye disease; computer vision syndrome; digital eye strain; diabetic retinopathy; Vitamin A; Vitamin C; copper; glutathione; zinc; selenium; magnesium; blue light damage; UV light damage; blue light reactive oxygen species; autophagy; ferroptosis; ROS cell death; superoxide dismutase; optic nerve gliomas; food deserts; myopia; free radicals
Online: 29 March 2023 (03:33:55 CEST)
CASE REPORT
|
doi:10.20944/preprints202406.1511.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
ibrutinib; 17p deletion; kidney biopsy; renal lymphomatous infiltration; monoclonal b cell lymphocytosis (mbl); complications of cll; venetoclax; chronic lymphocytic leukemia (cll); cll treatment; renal involvement in cll
Online: 24 June 2024 (07:41:28 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0629.v1
Subject:
Physical Sciences,
Biophysics
Keywords:
individual molecule tracking; individual molecule; single molecule; diffusion; thermodynamic jitter; live cell; cytoplasm; liquids; room temperature; continuous-time random walk (CTRW); Brownian motion; anomalous motion; computer simulation
Online: 11 June 2024 (08:12:32 CEST)
ARTICLE
|
doi:10.20944/preprints202301.0454.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cell stress response; heat shock protein 90 (HSP90); SCAN domain-containing proteins (SCAND); MZF1; heat shock factors (HSF); co-expression correlation; Kaplan-Meyer analysis; cancer patients prognosis
Online: 25 January 2023 (10:18:20 CET)
REVIEW
|
doi:10.20944/preprints202201.0366.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cell-free DNA; liquid biopsy; cancer; next-generation sequencing (NGS); minimal residual disease; measurable residual disease; molecular residual disease (MRD); leukemia; lymphoma; myeloma; myeloproliferative neoplasms; myelodysplastic syndrome
Online: 25 January 2022 (08:13:24 CET)
REVIEW
|
doi:10.20944/preprints202102.0409.v1
Subject:
Social Sciences,
Education
Keywords:
Professional development for scientists; tenure-track faculty; tenure; professoriate; professional development practicum; professional development experiential learning; Accomplishing Career Transitions; American Society for Cell Biology; Minorities Affairs Committee
Online: 18 February 2021 (10:43:19 CET)
REVIEW
|
doi:10.20944/preprints202007.0674.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
osteoarthritis; articular cartilage; degeneration; regeneration; therapeutic protein; growth factor; protein production platform; protein packaging cell line; transforming growth factor β (TGF-β); GP2-293 cells; TissueGene-C
Online: 28 July 2020 (10:16:51 CEST)
REVIEW
|
doi:10.20944/preprints201912.0386.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
resistance-associated secretory phenotype (RASP); extracellular vesicle (EV); exosome; oncosome; drug resistance; epithelial-mesenchymal transition (EMT); heat shock protein (HSP); cell stress response; hypoxia; acidosis; tumor immunology
Online: 29 December 2019 (13:46:21 CET)
REVIEW
|
doi:10.20944/preprints201912.0135.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
vascular homing peptide; cell penetrating peptide; angiogenesis; vascular heterogeneity; fibrosis; targeted delivery; decorin; transforming growth factor-β (tgf-β), bystander effect, cendr peptide; tissue regeneration; regenerative medicine
Online: 10 December 2019 (15:02:39 CET)
REVIEW
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Neuroendocrine Neoplasms; NOTCH; cancer driven genes; mutational mechanism; germline mutations.; small cell lung carcinoma; pancreatic NET; small bowel NET; medullary thyroid carcinoma; malignant castration-resistant prostatic cells
Online: 23 July 2019 (10:34:50 CEST)
ARTICLE
|
doi:10.20944/preprints202310.1525.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
glial cell line-derived neurotrophic factor; brain derived neurotrophic factor; cortisol; tumor necrosis factor-α; lacrimal fluid; blood serum; focal epilepsy; major depressive disorder; hypothalamic-pituitary-adrenocortical axis
Online: 24 October 2023 (10:16:57 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0068.v1
Subject:
Medicine And Pharmacology,
Otolaryngology
Keywords:
head and neck neoplasms; head and neck cancer; head and neck squamous cell carcinoma; radiotherapy; radiochemotherapy; salvage surgery; time interval; body composition; skeletal muscle; computed tomography scan; radiomics
Online: 4 September 2023 (02:41:55 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0113.v1
Subject:
Physical Sciences,
Atomic And Molecular Physics
Keywords:
Keywords: gas stopping cell; supersonic gas jet; in-gas-jet laser resonance ionization spectroscopy; double-nozzle technique; RF-only funnel; RF-buncher; gas dynamic and Monte Carlo simulations
Online: 2 August 2023 (02:31:21 CEST)
REVIEW
|
doi:10.20944/preprints202011.0245.v2
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
CD209; L-SIGN; CD209L; D-SIGN; C-type lectin; Cell Adhesion Molecule; C-type lectin domain family 4 member M; CLEC4M; LSECtin; CLEC4G; SARS-CoV-2; COVID-19
Online: 9 November 2020 (09:25:09 CET)
REVIEW
|
doi:10.20944/preprints201705.0090.v1
Subject:
Engineering,
Electrical And Electronic Engineering
Keywords:
Electric Vehicle; internal combustion engine; greenhouse gas; optimization techniques; Battery Electric Vehicle (BEV); Hybrid Electric Vehicle (HEV); Plug-in Hybrid Electric Vehicle (PHEV); Fuel Cell Electric Vehicle (FCEV).
Online: 10 May 2017 (17:44:51 CEST)
ARTICLE
|
doi:10.20944/preprints201612.0068.v2
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
modulation of nuclear gene expression; mitochondrial 18 kDa translocator protein (TSPO); TSPO ligand; PK 11195; 2-Cl-MGV-1; retrograde mitochondrial-nuclear signaling pathway; microscopy; mitochondria; cell nucleus
Online: 17 March 2017 (17:28:28 CET)
REVIEW
|
doi:10.20944/preprints201807.0432.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
Seed coat; pericarps; floral bracts; glumes; dead organs enclosing embryos; seed germination; seedling establishment; hydrolytic enzymes; ROS detoxifying enzymes; cell wall modification enzymes; nutrients; phytohormones; nucleases; chitinases; Brassicaceae; Poaceae
Online: 26 July 2018 (09:53:41 CEST)
REVIEW
|
doi:10.20944/preprints202401.0124.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Phage display; landscape phage; molecular evolution; affinity selection; recombinant antibodies, PC; prostate specific antigen (PSA); prostate-specific matrix antigen (PSMA); Enzyme-linked immunosorbent assay (ELISA); phage ELISA; phage capture assay; electrochemical biosensor; total prostate-specific antigen (t-PSA); free prostate-specific antigen (F-PSA); electrochemical impedance spectroscopy; label-free immunosensor
Online: 3 January 2024 (10:36:52 CET)
COMMUNICATION
|
doi:10.20944/preprints202312.1482.v1
Subject:
Medicine And Pharmacology,
Transplantation
Keywords:
IgG; protective level; vaccination; B cell; large granular lymphocytes (LGLs); common variable immunodeficiency (CVID); replacement therapy; hepatitis B immune globulins (HBIG); serum sickness; Hepatitis B virus (HBV); oncogenesis; hepatocellular carcinoma
Online: 20 December 2023 (10:53:25 CET)
REVIEW
|
doi:10.20944/preprints202310.0414.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
primate evolution genetics; noncoding genome; immunogenetics; neurogenetics; neurobiology; cell biology; molecular biology; neurological diseases; cardiovascular diseases; brain-immune system interactions; nucleic acid therapeutics; RNA interference; AAV vectors; blood-brain-barrier
Online: 8 October 2023 (07:20:59 CEST)
REVIEW
|
doi:10.20944/preprints202203.0103.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
plant immune response; reactive oxygen species; salicylic acid; reactive oxygen species-salicylic acid crosstalk; programmed cell death; hypersensitive response-conferred resistance; RBOH NADPH oxidases; chloroplastic redox state; biosensors; precision transcriptomics
Online: 7 March 2022 (14:46:28 CET)
REVIEW
|
doi:10.20944/preprints202111.0090.v2
Subject:
Medicine And Pharmacology,
Orthopedics And Sports Medicine
Keywords:
adipose-derived regenerative cells; ADRCs; adipose-derived stem cells; ADSCs; bone regeneration, cartilage regeneration; efficacy; point of care treatment; stem cell; tendon healing without scar formation; tendon regeneration; vaPS cells
Online: 12 November 2021 (11:44:31 CET)
ARTICLE
|
doi:10.20944/preprints202405.1606.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Oral squamous cell carcinoma; OSCC; oral cancer; miRNA; miRNA expression; genes; gene expression; hyperplasia; dysplasia; early invasion; early stage OSCC; in situ carcinoma; precancerous lesions; animal model; early diagnosis; liquid biopsy
Online: 24 May 2024 (08:38:17 CEST)
INTERESTING IMAGES
|
doi:10.20944/preprints202309.0462.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
claudin-18; cytopathology; colloid carcinoma (CC) of the pancreas; intraductal papillary mucinous neoplasm with high-grade dysplasia (IPMNHGD) of the pancreas; signet-ring cell; serial pancreatic juice aspiration cytological examination (SPACE)
Online: 7 September 2023 (10:45:29 CEST)
REVIEW
|
doi:10.20944/preprints202308.0299.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
safety of products of human origin; solid organ transplantation; hematopoietic stem-cell transplantation; West Nile virus; dengue virus; tick-borne encephalitis virus; Usutu virus; Chikungunya virus; Zika virus; mainland and overseas France
Online: 3 August 2023 (11:28:33 CEST)
ARTICLE
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Head and Neck Squamous Cell Carcinoma (HNSCC); the Cancer Genome Atlas (TCGA); Survival Analysis; Optimal Cutoff; Surgical Margin; Holistic Cancer Care; Therapeutic Relationship; Mindfulness Meditation; Transcriptomic Analysis; Effect Size; CAMK2N1; CALML5; FCGBP
Online: 7 July 2021 (08:48:26 CEST)
ARTICLE
|
doi:10.20944/preprints202402.0208.v1
Subject:
Engineering,
Automotive Engineering
Keywords:
5-way electric coolant control valve (PCCV : Penta-Control Coolant Valve); Fuel cell vehicle(FCEV); Thermal management system; Computational fluid dynamics; Moving grids technique; Cooling circuit; thermal mixing, flow inertia, dynamic flow chatacteristics
Online: 5 February 2024 (10:10:20 CET)
REVIEW
|
doi:10.20944/preprints202303.0126.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
sarcoidosis; Mycobacterium avium ss. paratuberculosis; MAP; non-caseating granuloma; caseating granuloma; Blau syndrome; early onset sarcoidosis; Crohn’s disease; cell wall deficient (CWD); L-form; Mycobacterium tuberculosis; acid-fast bacilli; SLC11a1 (NRAMP1); NOD2 (CARD15)
Online: 7 March 2023 (03:46:55 CET)
REVIEW
|
doi:10.20944/preprints202111.0253.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
Cell therapy; chronic limb-threating ischemia; peripheral artery disease; diabetes; atherosclerosis obliterans; thromboangiitis obliterans; personalized medicine; artificial intelligence; machine learning; genome-wide association studies; transcriptome-wide association studies; clonal hematopoiesis of indeterminate potential.
Online: 15 November 2021 (11:18:43 CET)
CASE REPORT
|
doi:10.20944/preprints201810.0491.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
cytomegalovirus (CMV); infection, reactivation, epidemiology, host-virus interaction, CMV-specific IgG; protective IgG level, avidity, adoptive/acquired immune response, hematopoietic stem cell transplantation (HSCT); secondary immunodeficiency, Quantiferon, pentamer, β2-microglobulin/beta 2-Microglobulin
Online: 22 October 2018 (11:53:47 CEST)
CASE REPORT
|
doi:10.20944/preprints202308.1373.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
Large B-cell lymphoma (LBCL); Immunohistochemical (IHC) staining; Glucoseregulated protein 94 (GRP94); CYP3A4; Multidrug resistance protein 1 (MDR1); Aldo-keto reductase family 1 member C3 (AKR1C3); Multi-drug resistance-associated protein 1 (MRP1); P53
Online: 18 August 2023 (11:42:22 CEST)
ARTICLE
|
doi:10.20944/preprints201907.0347.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
autograft; embryonic stem cells (ESC); growth factor (GF); hereditary retinal disease; induced pluripotent stem cells (iPSCs); Limoli retinal restoration technique (LRRT); mesenchymal stem cell (MSC); retinitis pigmentosa; spectral domain-optical coherence tomography (SD-OCT)
Online: 31 July 2019 (04:45:51 CEST)
REVIEW
|
doi:10.20944/preprints202402.0963.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
POMS; Pediatric Onset Multiple Sclerosis; Disease-modifying therapies; DMT; Pediatric MS; Interferons; Finglolimod; Teriflunomide; Cyclophosphamide; Rituximab; Ocrelizumab; Daclizumab; Alemtuzumab; Natalizumab; Ofatumumab; Siponimod; Vitamin D; TCR vaccine; Stem cell therapy; Glatiramer acetate; Azathioprine; Dimethyl fumarate; Mitoxantrone
Online: 19 February 2024 (14:52:05 CET)
ARTICLE
|
doi:10.20944/preprints202309.1265.v1
Subject:
Engineering,
Other
Keywords:
Multijunction solar cells; IIIV semiconductors; TCAD simulation; cell optimization; predictive profiling; CIGS absorbers; spectral utilization; currentvoltage characteristics; external quantum efficiency; GaAs replacement; bottom junction; thin films; high efficiency; photovoltaics; epitaxial growth; stacked junctions; light absorption
Online: 19 September 2023 (07:48:35 CEST)
REVIEW
|
doi:10.20944/preprints202212.0032.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
ACE2; Ang II; angiotensin(1-7); AT1R; Cathepsin; cell entry; COVID-19; Endocytosis; ERK1/2; Furin; IL-1β; IL-6; MAPK; MasR; NF-κB; PLC; PKC; RAS; RBD; SARS-CoV2; S protein; TMPRSS2; TNF-α
Online: 2 December 2022 (02:19:48 CET)
REVIEW
|
doi:10.20944/preprints202211.0271.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
cisplatin; carboplatin; oxaliplatin; cellular uptake; DNA damage; transcription regulation; non-nuclear targets; chemoresistance; mechanisms of action; clinical usages; influx and efflux pumps; ribosome biogenesis; ER stress response; immunogenic cell death; interstrand and intrastrand DNA cross-links.
Online: 15 November 2022 (03:38:06 CET)
ARTICLE
|
doi:10.20944/preprints202401.1406.v1
Subject:
Biology And Life Sciences,
Parasitology
Keywords:
Leishmania infectivity in mammalian hosts; inserts of leishmaniases and coinfections in companion animals; clinical and histopathologic features of natural zoonotic canine leishmaniasis; cell communication by parasite-derived extracellular vesicles; in vitro models advance to target parasite-secreted lipid bound vesicles
Online: 19 January 2024 (03:14:14 CET)
ARTICLE
|
doi:10.20944/preprints202301.0489.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
multidrug resistance; MDR; EPB (Xenorhabdus; (X. budapestensis; X. szentirmaii; X. innexii); and Photorhabdus) species); CFCM (cell-free conditioned media); NR-AMP (non-ribosomal-templated antimicrobial peptides); anti-microbial; (anti-bacterial; - anti-coccidial; -anti-protist; - activity; cytotoxicity; in vitro; in situ (local) bioavailablity; XENOFOOD; allometry
Online: 27 January 2023 (06:21:56 CET)
REVIEW
|
doi:10.20944/preprints202403.0720.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
early onset gastrointestinal malignancies; young adult cancer; early onset colorectal cancer; early onset esophageal cancer; esophageal adenocarcinoma; esophageal squamous cell carcinoma; early onset gastric cancer; early onset pancreatic cancer; early onset liver cancer; gastrointestinal malignancy; hepatocellular carcinoma; BRCA mutation; ATM mutation; MLH1; MSH2; MSH6; PRSS1; early onset biliary malignancy
Online: 12 March 2024 (14:33:15 CET)
ARTICLE
|
doi:10.20944/preprints202105.0242.v1
Subject:
Computer Science And Mathematics,
Mathematics
Keywords:
Lorentzian SRT-transformation factors as solutions of oscillation-equations Holger Döring IQ-Berlin-Spandau Germany e-mail:[email protected]:Shown is the derivation of Lorentz-Einstein k-factor in SRT as an amplitude-term of oscillation-differential equations of second order.This case is shown for classical Lorentz-factor as solution of an equation for undamped oscillation as well as the developed theorem as a second solution for advanced SRT of fourth order with an equation for damped oscillation-states.This advanced term allows a calculation for any velocities by real rest mass.key-words: undamped oscillation; SRT; k-factor; Differential-equation of second order; Einstein-Lorentz; Amplitude-analogy; damped oscillation; developed SRT of fourth order
Online: 11 May 2021 (11:16:44 CEST)
ARTICLE
|
doi:10.20944/preprints201810.0088.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
There are many molecules used as drug carrier. TUD-1 is a newly synthesized mesoporous silica (SM) molecule possess two important features; consists of mesoporous so it is very suitable to be drug carrier in addition to that it has the ability to induce apoptosis in cancer cells. However, the effect of TUD-1 appears to act as cell death inducer, regardless of whether it is necrosis or apoptosis. Unfortunately, recent studies indicate that a proportion of cells undergo necrosis rather than apoptosis, which limits the use of TUD-1 as a secure treatment. On the other hand, lithium considered as necrosis inhibitor element. Hence, current study based on the idea of production a new Li/TUD-1 by incorporated mesoporous silica (TUD-1 type) with lithium in order to produce a new compound that has the ability to activate apoptosis by mesoporous silica (TUD-1 type) and at the same time can inhibit the activity of necrosis by lithium. Herein, lithium was incorporated in TUD-1 mesoporous silica by
Online: 4 October 2018 (15:54:02 CEST)