ARTICLE
|
doi:10.20944/preprints202406.2036.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
REE; Bacillus stratosphericus; lanthanide toxicity; environmental screening; complexation equilibria; cerium; lanthanide accumulation; Debaryomyces hansenii
Online: 1 July 2024 (03:59:35 CEST)
ARTICLE
|
doi:10.20944/preprints202405.0243.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Alzheimer’s disease; amyloid precursor protein; cerebral organoid; disease modeling; drug screening; induced pluripotent stem cells; organoids; tau pathology
Online: 6 May 2024 (07:37:30 CEST)
ARTICLE
|
doi:10.20944/preprints202402.1648.v1
Subject:
Chemistry And Materials Science,
Other
Keywords:
Fluorescent carbohydrate library; High-throughput phenotypic screening; Gating-Oriented Live-cell Distinction; Solute carrier; B cell specific probe
Online: 29 February 2024 (17:00:38 CET)
ARTICLE
|
doi:10.20944/preprints202401.0707.v1
Subject:
Chemistry And Materials Science,
Food Chemistry
Keywords:
flavor blueprint; black tea infusions; sensomics-based-expert-system; industrial quality control; Artificial Intelligence sensing; accurate flavor screening
Online: 9 January 2024 (09:20:56 CET)
ARTICLE
|
doi:10.20944/preprints202304.0082.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
COVID-19; drug repurposing; methotrexate; EXSCALATE; virtual screening; molecular docking; antiviral activity; SARS-CoV-2; viral entry; nsp13
Online: 6 April 2023 (09:21:51 CEST)
ARTICLE
|
doi:10.20944/preprints202202.0349.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Hypoxia-inducible factor; cancer; hypoxia; drug discovery; medicinal chemistry; virtual screening; molecular dynamics simulation; MM-PBSA; Drug discovery
Online: 28 February 2022 (08:40:24 CET)
ARTICLE
|
doi:10.20944/preprints202008.0724.v1
Subject:
Biology And Life Sciences,
Forestry
Keywords:
Shisham mortality; Fusarium solani f. sp. dalbergiae; in vitro screening; genetic variation; Fusarium wilt; plant-microbe interaction; gnotobiota
Online: 31 August 2020 (16:21:02 CEST)
ARTICLE
|
doi:10.20944/preprints202006.0091.v1
Subject:
Computer Science And Mathematics,
Computer Science
Keywords:
Breast Cancer Screening; Digital Image Elasto Tomography (DIET); Image Noise Removal, Image Enhancement; Multiple Frame Noise Removal (MFNR)
Online: 7 June 2020 (14:53:34 CEST)
REVIEW
|
doi:10.20944/preprints201812.0273.v3
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
mutations; disease-causing mutations; polymorphism; folding free energy change; binding free energy change; drug discovery; in silico screening
Online: 28 January 2019 (11:39:23 CET)
REVIEW
|
doi:10.20944/preprints201807.0116.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
chemical space; chemoinformatics; data mining; databases; DNMT inhibitors; drug discovery; epi-informatics; molecular modeling; similarity searching; virtual screening
Online: 6 July 2018 (10:04:44 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0762.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
high-throughput screening; metabolic stability; ambient mass spectrometry; LA-REIMS; biomimetic metalloporphyrin; lead profiling; in vitro models; drug metabolism
Online: 12 June 2024 (14:15:32 CEST)
ARTICLE
|
doi:10.20944/preprints202311.1911.v1
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
infrared thermal imaging; toddler’s fracture; bone fracture screening; infrared thermal image processing and analysis; artificial intelligence; emergency medicine; orthopaedics
Online: 29 November 2023 (16:40:58 CET)
ARTICLE
|
doi:10.20944/preprints202309.0566.v1
Subject:
Medicine And Pharmacology,
Emergency Medicine
Keywords:
Emergency department; Elderly; Geriatric assessment; Frailty; Frailty transitions; Mortality; Clinical Frailty Scale; Identification of Seniors at Risk screening tool.
Online: 8 September 2023 (13:00:05 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1699.v1
Subject:
Medicine And Pharmacology,
Psychiatry And Mental Health
Keywords:
intimate partner violence; pregnancy; gestatinoal intimate partner violence; adverse outcomes; maternity staff; screening; domestic abuse; trauma; institutional support; teamwork
Online: 24 August 2023 (09:44:26 CEST)
ARTICLE
|
doi:10.20944/preprints202210.0100.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
screening after pulmonary embolism; chronic thromboembolic pulmonary disease; chronic thromboembolic pulmonary hypertension; diagnostic work-up of post-pulmonary syndrome
Online: 9 October 2022 (02:09:20 CEST)
REVIEW
|
doi:10.20944/preprints202010.0179.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Non Michaelis-Menten Kinetics; High-throughput screening; allostery; cooperativity; processive kinetics; distributive kinetics; single-molecule; auto-catalytic; drug discovery
Online: 8 October 2020 (13:34:16 CEST)
ARTICLE
|
doi:10.20944/preprints202005.0199.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
SARS-CoV-2; COVID-19; CADD; virtual screening; approved drugs; drug repurposing; essential targets; molecular docking; molecular dynamics simulations
Online: 11 May 2020 (13:14:18 CEST)
COMMUNICATION
|
doi:10.20944/preprints202002.0418.v2
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
virtual screening; molecular docking; drug repurposing; drug repositioning; anti-viral drugs; Coronavirus; COVID-19; 2019-nCoV; SARS-CoV-2
Online: 9 March 2020 (02:29:04 CET)
CASE REPORT
|
doi:10.20944/preprints201808.0343.v1
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
international adoptions; asymptomatic and misidentified parasitosis; intestinal parasite infections, IPIs; Giardia lamblia; Trichuris spp.; Strongyloides stercoralis; IPIs screening guidelines
Online: 19 August 2018 (05:30:16 CEST)
REVIEW
Subject:
Biology And Life Sciences,
Virology
Keywords:
Chikungunya virus; alphavirus; antiviral therapy; direct-acting antivirals; host-directed antivirals; in silico screening; in vivo validation; antiviral drug development
Online: 10 June 2021 (09:15:45 CEST)
REVIEW
|
doi:10.20944/preprints202009.0256.v1
Subject:
Chemistry And Materials Science,
Physical Chemistry
Keywords:
attractive and repulsive forces; Debye’s screening length (1/k); Poisson-Boltzmann (PB) equation; food colloids; coagulation; stabilizers; lipids; polymers; electrolytes
Online: 11 September 2020 (10:05:50 CEST)
ARTICLE
|
doi:10.20944/preprints201910.0283.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
chronic inflammation; biomarker panels; leukocyte count; C-reactive protein; related syndromes and pathologies; risk assessment; screening programmes; ageing; elderly's health
Online: 25 October 2019 (04:16:43 CEST)
ARTICLE
|
doi:10.20944/preprints201909.0123.v1
Subject:
Medicine And Pharmacology,
Tropical Medicine
Keywords:
Active case findings; Tuberculosis; TOUCH Agent; High TB burden area; TB Surveillance; 4S Screening; THALI Project; SORT IT; Operational Research
Online: 11 September 2019 (13:30:30 CEST)
REVIEW
|
doi:10.20944/preprints202407.1479.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Inborn errors of immunity (IEI); Chronic granulomatous disease (CGD); NADPH oxidase; Nitroblue tetrazolium (NBT); Dihydrorhodamine (DHR); Genetic testing; Genomic testing; Screening
Online: 18 July 2024 (14:38:08 CEST)
ARTICLE
|
doi:10.20944/preprints201807.0476.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
BRCA1, BRCA2, Hereditary Breast and Ovarian Cancer, Lynch Syndrome, Hereditary cancer, Family history screening. Risk assessment, Digital tool, Health information technology
Online: 25 July 2018 (09:59:26 CEST)
ARTICLE
|
doi:10.20944/preprints202312.1430.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Alzheimer’s disease 1; plasma amyloid 2; SIMOA 3; plasma Aβ42/Aβ40 ratio 4; amyloid prediction 5; biomarkers 6; Alzheimer’s disease screening 7
Online: 19 December 2023 (10:19:53 CET)
ARTICLE
|
doi:10.20944/preprints202311.0727.v1
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
newborn screening; lysosomal storage disease; Pompe disease; Mucopolysaccharidosis type I; Gaucher disease; Fabry disease; second tier test; tandem mass spectrometry; glycosaminoglycans; lysosphingosine.
Online: 10 November 2023 (16:19:05 CET)
ARTICLE
|
doi:10.20944/preprints202306.1818.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Alternative Splicing; two-colour (GFP/RFP) Fluorescent Reporter; MAPT; Exon-Skipping; FTDP-17; High Content Screening; siRNA; Nucleic Acids Therapeutics; Drug discovery
Online: 26 June 2023 (13:55:26 CEST)
ARTICLE
|
doi:10.20944/preprints202106.0020.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Vesicular Stomatitis; Herpes Simplex; Yellow Fever; Animal Viruses; Plaque Assay; Real-time; Live Cell Imaging, Automated Image Analysis; DNA Fluorescent Dyes, Antiviral Screening
Online: 1 June 2021 (10:40:37 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0073.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
workplace testing; economic analysis; COVID-19; asymptomatic screening; mass testing; employee population health; return to work practices; SARS-CoV-2; surveillance; workplace mitigation
Online: 6 May 2021 (11:34:57 CEST)
ARTICLE
|
doi:10.20944/preprints202103.0403.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
non-canonical branched chain amino acids; scale-down; strain screening; mixed-acid fermentation; pyruvate pulse; norvaline; norleucine; fed-batch cultivation; bioreactor; Enpresso; Enbase
Online: 16 March 2021 (09:11:34 CET)
REVIEW
|
doi:10.20944/preprints202308.0434.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
In silico studies; drug discovery; SARS-CoV-2; molecular docking; virtual screening; molecular dynamics simulations; drug candidates; antiviral activity; receptor-ligand complex; drug design
Online: 4 August 2023 (11:11:21 CEST)
ARTICLE
|
doi:10.20944/preprints202403.0412.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
Lynch syndrome; colorectal cancer; germline pathogenic variant MLH1:c.1528C> T; Human leukocyte antigen (HLA); age at cancer diagnosis; genetic risk modifiers; personalized cancer screening
Online: 7 March 2024 (07:36:11 CET)
ARTICLE
|
doi:10.20944/preprints201911.0023.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
monoclonal antibodies; Mabs; fusion; false positives; hapten immunoassays; competitive immunoassays; ELISA; antibody validation; antibody quality; microarray; hybridoma technology; linker recognition; high-throughput screening; HTS; heterology concept
Online: 3 November 2019 (17:00:59 CET)
ARTICLE
|
doi:10.20944/preprints202301.0340.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
alternative food; resilient food; distributed production; edible plants; existential risk; food security; global catastrophic risk; leaf concentrate; leaf protein; non-target screening; resilience; sustainable food systems; toxins
Online: 19 January 2023 (01:57:51 CET)
ARTICLE
|
doi:10.20944/preprints202005.0001.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
CRISPR-Cas9; high-content screening (HCS); fluorescent-activated cell sorting (FACS); Parkinson's disease (PD); patient-derived iPS; single-cell clones; isogenic cell lines; SNCA; alpha-synuclein; A30P
Online: 2 May 2020 (11:20:20 CEST)
ARTICLE
|
doi:10.20944/preprints202310.1811.v1
Subject:
Medicine And Pharmacology,
Obstetrics And Gynaecology
Keywords:
Cervical cancer; HPV screening; Prevention strategies; Human Papillomavirus; HIV interaction; "Test and Treat" approach; Number Needed to Treat; Positive Predictive Value; Negative Predictive Value; Risk management; Global health challenges
Online: 27 October 2023 (13:21:23 CEST)
COMMUNICATION
|
doi:10.20944/preprints202404.1556.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Methylated Cyclodextrin; Cyclodextrin; KLEPTOSE® CRYSMEB; anti-inflammatory; immunity; HUVEC; BCS; T cell; Diversity PLUS® Panel; chemokines; polyunsaturated fatty acid; lipoxins; resolvins; maresins; protectins; Peripheral Blood Mononuclear Cell, screening; cytokine
Online: 24 April 2024 (07:09:16 CEST)
COMMUNICATION
|
doi:10.20944/preprints202402.0599.v2
Subject:
Physical Sciences,
Mathematical Physics
Keywords:
nonrelativistic quantum electrodynamics; NRQED; background magnetic field; gauge invariance; Lagrangian; electron self-interactions; electromagnetic field interactions; path integral formalism; effective action; photon propagator; screening effects; density components; current components; Laurent expansions; hydrodynamic limit; equations of motion; Poiseuille-like flow; Navier-Stokes equation; relativistic hydrodynamics; linearized equations; nonrelativistic limit; quantum electrodynamical analysis
Online: 7 March 2024 (09:33:28 CET)