REVIEW
|
doi:10.20944/preprints202312.1427.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
oncogenes; aerobic glycolysis; lactate receptors; nutrient transporters; glutamine addiction; one-carbon metabolism; glutaminolysis; reductive carboxylation; oncometabolites; tumor microenvironment
Online: 19 December 2023 (14:08:42 CET)
ARTICLE
|
doi:10.20944/preprints202111.0229.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Total metabolic tumor volume; bone marrow to liver ratio; PET/CT; overall survival; immunotherapy; immune checkpoint inhibitor; standardized uptake value; response prediction
Online: 12 November 2021 (14:59:35 CET)
ARTICLE
|
doi:10.20944/preprints202309.1729.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
quantiative ultrasound; attenuation coefficient; backscatter-distribution coefficient; liver stiffness; non-alcoholic fatty liver disease; metabolic-associated fatty liver disease; hepatic steatosis; ultrasound-estimated fat fraction; proton density fat fraction
Online: 26 September 2023 (05:36:41 CEST)
REVIEW
|
doi:10.20944/preprints202306.1113.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
Inflammatory bowel disease; Colitis-associated colorectal cancer; exogenous frees hemoglobin alpha chain; Fenton reaction; DNA damage; haptoglobin; deferoxamine; flavonoids; hydrogen peroxide; hygiene; iron; nanomedicine; oxidative stress; polyphenol; pharmaceutical therapy
Online: 16 June 2023 (07:11:38 CEST)
ARTICLE
|
doi:10.20944/preprints202401.0070.v2
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cancer growth; tumor metastasis; cancer's Warburg effect; p53; p53 (re)activators; mitochondrial apoptosis; cytochrome c release; tumoricidal drug effect
Online: 4 January 2024 (09:34:19 CET)
ARTICLE
|
doi:10.20944/preprints202204.0183.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
resistant TNBC; intra-tumoral heterogeneity; breast cancer relapse; breast cancer epigenome; me-tastasis prevention; intrinsic resistance of cancer; tumor adaptability; targeting resistant cancer
Online: 20 April 2022 (04:16:31 CEST)
ARTICLE
|
doi:10.20944/preprints202110.0359.v2
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
brain; pituitary adenoma; Dysembryoplastic neuroepithelial tumor; DNET; Ganglioglioma; deep learning; digital pathology; convolutional neural network; computer vision; machine learning; convolutional neural network; CNN
Online: 26 October 2021 (14:10:11 CEST)
ARTICLE
|
doi:10.20944/preprints202002.0003.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
drug repositioning/repurposing; dopamine transporter (DAT); benztropine; tumoroids; signal transducer and activator of transcription (STAT); circulating tumor cells (CTC); three-dimensional (3D) culture
Online: 3 February 2020 (03:16:54 CET)
ARTICLE
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
breast cancer tumor; classification; majority-based voting mechanism; multilayer perceptron learning network; simple logistic regression; stochastic gradient descent learning; wisconsin breast cancer dataset
Online: 27 November 2019 (09:51:31 CET)
ARTICLE
|
doi:10.20944/preprints202008.0470.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Amyotrophic Lateral Sclerosis (ALS); Fronto-Temporal-Lobar-Dementia; Tauopathies; synaptic plasticity; long-term potentiation; spatial learning; inositol signaling; neurexin; K-homology RNA-binding domain; Fragile-X-associated Tremor-Ataxia syndrome
Online: 21 August 2020 (04:39:19 CEST)
ARTICLE
|
doi:10.20944/preprints202309.1752.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
Hepatocellular carcinoma; Transarterial radioembolization; Yttrium-90; Locoregional treatment; Portal vein tumor thrombosis; Overall survival; Progression-free survival; Skeletal muscle mass; Sarcopenia; Body mass index.
Online: 26 September 2023 (08:22:48 CEST)
ARTICLE
|
doi:10.20944/preprints202304.1090.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Invasive lobular cancer; pleomorphic invasive lobular cancer; tumor-infiltrating lymphocytes; programmed cell death 1; programmed cell death ligand 1; 22C3 assay; SP142 assay; survival
Online: 28 April 2023 (03:22:03 CEST)
ARTICLE
|
doi:10.20944/preprints202202.0046.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Cancer; tumor homing peptide; in silico drug discovery; complex network; chemical space network; centrality measure; similarity searching, group fusion; motif discovery; starPep toolbox software
Online: 3 February 2022 (10:14:05 CET)
ARTICLE
|
doi:10.20944/preprints202201.0380.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Therapeutic biomarkers; circulating tumor cells; Immunocytochemistry; targeted therapy; Fluorescence in situ hybridization (FISH); Immune Checkpoint Inhibitors; Liquid Biopsy; Hormonal Treatments; Breast Cancer; Lung Cancer
Online: 25 January 2022 (11:31:05 CET)
REVIEW
|
doi:10.20944/preprints202407.1569.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Cancer; tumor tissue; microwave imaging; two-photon excitation; second harmonic generation; third harmonic generation; Raman Scattering; Life-time two photon fluorescence; two-photon photodynamic therapy
Online: 19 July 2024 (10:53:17 CEST)
ARTICLE
|
doi:10.20944/preprints202403.0398.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
immune escape; tumor immunity; immune checkpoint; oral squamous cell carcinoma; programmed death receptor-1 (PD-1); programmed cell death 1-ligand 1 (PD-L1); CD47
Online: 7 March 2024 (07:49:57 CET)
REVIEW
|
doi:10.20944/preprints202312.0717.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Cancer immunotherapy 1; Resistance 2; Tumor microenvironment 3; Combination therapies 4; Immune checkpoint targets 5; Adoptive cell therapies 6; Cancer vaccines 7; Personalized medicine 8.
Online: 11 December 2023 (17:53:38 CET)
ARTICLE
|
doi:10.20944/preprints202111.0460.v1
Subject:
Medicine And Pharmacology,
Dietetics And Nutrition
Keywords:
Maintenance hemodialysis (MHD) patient; Low-phosphate meal; CKD-MBD (chronic kidney disease-related mineral and bone disorder); Proinflammatory cytokine; TNF-α (tumor necrosis factor-alpha)
Online: 24 November 2021 (15:27:03 CET)
ARTICLE
|
doi:10.20944/preprints202406.1018.v1
Subject:
Medicine And Pharmacology,
Emergency Medicine
Keywords:
Pulmonary contusion; endothelin-1; ET-1; hypoxia-inducible factor-1 HIF-1; nuclear factor-kappa B; tumor necrosis factor-α pro-oxidant antioxidant balance; lung tissue
Online: 14 June 2024 (11:27:55 CEST)
REVIEW
|
doi:10.20944/preprints202309.0633.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
metastatic hormone-sensitive prostate cancer; new hormonal agents; transcriptomic profiling; DNA damage repair genes; tumor suppressor genes; androgen receptor; immunotherapy; CDK4/6 inhibitors; PARP inhibitors; AKT inhibitors.
Online: 11 September 2023 (07:17:07 CEST)
COMMUNICATION
|
doi:10.20944/preprints202007.0709.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
intrinsic multi-drug resistance; acquired multi-drug resistance; circulating tumor cells; single cells; cell clusters; cell monolayer; multi-cellular spheroids; cytometry of reaction rate constant; ovarian cancer
Online: 30 July 2020 (09:01:50 CEST)
CASE REPORT
|
doi:10.20944/preprints202308.1373.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
Large B-cell lymphoma (LBCL); Immunohistochemical (IHC) staining; Glucoseregulated protein 94 (GRP94); CYP3A4; Multidrug resistance protein 1 (MDR1); Aldo-keto reductase family 1 member C3 (AKR1C3); Multi-drug resistance-associated protein 1 (MRP1); P53
Online: 18 August 2023 (11:42:22 CEST)
ARTICLE
|
doi:10.20944/preprints202310.1525.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
glial cell line-derived neurotrophic factor; brain derived neurotrophic factor; cortisol; tumor necrosis factor-α; lacrimal fluid; blood serum; focal epilepsy; major depressive disorder; hypothalamic-pituitary-adrenocortical axis
Online: 24 October 2023 (10:16:57 CEST)
REVIEW
|
doi:10.20944/preprints202401.2238.v1
Subject:
Biology And Life Sciences,
Other
Keywords:
N-glycosylation; disease; conformational mutant; aberrant protein assembly; energy landscape; SARS-CoV-2 spike protein; glucose regulated protein 94 (GRP94); prion protein; disease-associated protein conformation; protein dynamics; protein assembly mutation; gain-of-function conformational change
Online: 31 January 2024 (14:12:55 CET)
REVIEW
|
doi:10.20944/preprints202209.0482.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Telomerase reverse transcriptase; TERT; TERT promoter; TERTp; human papillomavirus; HPV; Epstein Barr virus (EBV); Kaposi sarcoma-associated herpesvirus; HHV-8; hepatitis B virus; HBV; hepatitis C virus; HCV; human T-cell leukemia virus-1; HTLV-1
Online: 30 September 2022 (10:11:58 CEST)
ARTICLE
|
doi:10.20944/preprints202304.0625.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
adverse drug reaction; cisplatin liposomes; circulating tumor cells; enhanced permeability and retention effect; nephrotoxicity; pulmonary metastasis of pancreatic cancer; quality of life; recurrent liver metastases from primary nasal cancer
Online: 20 April 2023 (07:52:10 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0729.v1
Subject:
Medicine And Pharmacology,
Complementary And Alternative Medicine
Keywords:
hormonal replacement therapy (HRT); mindfulness-based stress reduction (MBSR); Risk reducing salpingo-oophorectomy (RRSO); Breast Cancer Associated Susceptibility Protein Type 1/2 (BRCA1/2) mutations; Menopause rating scale (MRS); menopause/perimenopause/postmenopausal; psychological symptoms; physical activity/exercise; breast cancer
Online: 12 June 2024 (00:04:00 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0646.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
androgen deprivation therapy (ADT); anti-tumor efficacy of hormones; estetrol (E4); High-dose estetrol (HDE4); PCombi study; testosterone (T); prostate-specific antigen (PSA); follicle-stimulating hormone (FSH); insulin-like growth factor-1 (IGF-1)
Online: 11 June 2024 (08:12:13 CEST)
ARTICLE
|
doi:10.20944/preprints202401.2166.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
implant-based breast reconstruction; SMI surface roughness; foreign body response (FBR); acute wound proteome; chronic wound proteome; antimicrobial humoral response; capsular fibrosis; surgical site microbiome; SMI-adhesive microbiome; implant-associated biofilm formation; SMI topography specific antimicrobial response; Staphylococcus transmission at surgical site; immunomics
Online: 31 January 2024 (05:46:56 CET)
ARTICLE
|
doi:10.20944/preprints202406.0122.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Tissue agnostic drug development; Pembrolizumab; Microsatellite instability-high (MSI-H); Tumor mutational burden-high (TMB-H); Dostarlimab-gxly; Larotrectinib; Entrectinib; Neurotrophic tyrosine kinase (NTRK); Dabrafenib and trametinib; V-Raf Murine Sarcoma Viral Oncogene Homolog B V600E (BRAFV600E); Selpercatinib; Rearranged during transfection (RET); Precision oncology.
Online: 3 June 2024 (16:08:38 CEST)
REVIEW
|
doi:10.20944/preprints202407.1456.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
advanced therapy medicinal products (ATMPs); chimeric antigen receptors (CAR-T cells); B acute lymphoblastic leukaemia (B-ALL); food and drug administration (FDA); systemic lupus erythematosus (SLE); idiopathic inflammatory myositis (IIM); systemic sclerosis (SS); memorial sloan kettering cancer centre (MSKCC); hematopoietic stem cell transplantation [HSCT], non-Hodgkin’ s cell lymphoma (NHCL); multiple myeloma (MM); follicular lymphoma; (FL); large B cell-lymphoma (LBCL); mantle cell lymphoma (MCL); myeloid-derived suppressor cells (MDSCs); rheumatoid arthritis (RA); immune effector cell-associated neurotoxicity syndrome (ICANS); natural killer group member D ligands (NKG2DLs); acute myelogenous leukaemia (AML)
Online: 18 July 2024 (08:03:12 CEST)
ARTICLE
|
doi:10.20944/preprints201802.0163.v1
Subject:
Physical Sciences,
Optics And Photonics
Keywords:
optical metamaterials; fundamental concepts in photonics; light-matter interactions at the subwavelength and nanoscale; fundamental understanding of linear and nonlinear optical processes in novel metamaterials underpinning photonic devices and components; advancing the frontier of nanophotonics with the associated nanoscience and nanotechnology; nanostructures that can serve as building blocks for nano-optical systems; use of nanotechnology in photonics; nonlinear nanophotonics, plasmonics and excitonics; subwavelength components and negative index materials; slowing, store, and processing light pulses; materials with such capabilities that could be used for optical sensing, tunable optical delay lines, optical buffers, high extinction optical switches, novel image processing hardware, and highly-efficient wavelength converters
Online: 26 February 2018 (11:24:39 CET)