REVIEW
|
doi:10.20944/preprints202104.0517.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
CAR T-cells; chimeric antigen receptor T cells; cytokine release syndrome; central nervous system toxicity; neurotoxicity; adverse events; pathophysiology
Online: 19 April 2021 (21:17:34 CEST)
ARTICLE
|
doi:10.20944/preprints202209.0359.v1
Subject:
Computer Science And Mathematics,
Applied Mathematics
Keywords:
Hematological malignancies; treatment outcomes; CAR-T cell exhaustion; memory 22 pool, functional CAR-T cells; antigen dependent CAR-T expansion
Online: 23 September 2022 (05:33:24 CEST)
REVIEW
|
doi:10.20944/preprints202007.0016.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
myeloma; BCMA; bispecific T-cell engager; antibody-drug conjugates; chimeric antigen receptor T-cells; belantamab mafodotin; idecabtagene vicleucel; JNJ-68284528
Online: 3 July 2020 (07:30:57 CEST)
ARTICLE
|
doi:10.20944/preprints202401.1929.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
PitNETs; alternative splicing, TrkAIII splice variant; HIF2a, Splice factors SF3B1, U2AF and SRSF2, hotspot SF3B1 mutation, Xbp1, JCPyV large T antigen
Online: 26 January 2024 (15:15:02 CET)
ARTICLE
|
doi:10.20944/preprints202104.0512.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
hepatitis B virus (HBV); Myr47 lipopeptide; cellular uptake; liposomes; sodium taurocholate cotransporting polypeptide (NTCP); HBV surface antigen (HBsAg); apolipoprotein E (ApoE)
Online: 19 April 2021 (17:08:53 CEST)
REVIEW
|
doi:10.20944/preprints202012.0795.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
T cells; chimeric antigen receptor; transgenic T-cell receptor; tumor-infiltrating lymphocytes; exhaustion; terminal differentiation; senescence; apoptosis; adoptive cell transfer; immunotherapy
Online: 31 December 2020 (12:16:55 CET)
ARTICLE
|
doi:10.20944/preprints202303.0253.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
ASFV; humoral responses; ASFV capsid proteins; ASFV vaccines; ASFV immunity; antigen discovery; luciferase antibody capture assay; luciferase immunoprecipitation assay; viral hemorrhagic fever.
Online: 14 March 2023 (09:43:57 CET)
ARTICLE
|
doi:10.20944/preprints202407.0549.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
single-molecule FRET; single-molecule microscopy; receptor-ligand interaction; T cell receptor; bond lifetime quantification; T cell activation; antigen sensitivity; simulation; survival analysis
Online: 9 July 2024 (03:56:29 CEST)
REVIEW
|
doi:10.20944/preprints202406.0155.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
CAR-T cell therapy; Hematologic malignancies; Cytokine release syndrome; Antigen mutation; γ δ CAR-T cells; Multi-targeted CAR-T cells; Precision medicine
Online: 4 June 2024 (16:12:58 CEST)
REVIEW
|
doi:10.20944/preprints202401.2227.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Cytolytic Activity (CYT); Tumor-Infiltrating Lymphocytes (TILs); Gene Expression Profiling; Spatial Analysis Techniques; Immune Checkpoint Pathways; Tumor Microenvironment (TME); Antigen Presentation; Metabolic Pathways
Online: 31 January 2024 (12:32:26 CET)
ARTICLE
|
doi:10.20944/preprints202311.0688.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
melanoma; metastasis; overall survival; progression-free survival; side effects; Nivolumab; Ipilimumab; anti-programmed death-1 antibodies; anti-cytotoxic T-lymphocyte antigen-4 antibodies.
Online: 10 November 2023 (11:05:56 CET)
ARTICLE
|
doi:10.20944/preprints202308.1485.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
breast cancer; pathologic complete response; tumour-infiltrating lymphocytes; neoadjuvant systemic therapy; CD8 antigen; forkhead box P3; programmed cell death 1 receptor; chemokine CXCL13
Online: 22 August 2023 (07:32:48 CEST)
ARTICLE
|
doi:10.20944/preprints202408.1200.v1
Subject:
Public Health And Healthcare,
Health Policy And Services
Keywords:
COVID-19 Testing; Queueing Theory; M/M/c Model; Mass Gatherings; Operational Efficiency; Agile Management; System Throughput; Public Health Emergency Management; Antigen Testing; Process Optimization
Online: 16 August 2024 (04:53:00 CEST)
ARTICLE
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
point-of-care assay; membrane tests; immunochromatography; lateral flow immunoassay; immune response; detection of antibodies; antigen-antibody reactions; mathematical modelling; assay sensitivity; limit of detection
Online: 20 November 2020 (10:50:49 CET)
ARTICLE
|
doi:10.20944/preprints202403.0412.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
Lynch syndrome; colorectal cancer; germline pathogenic variant MLH1:c.1528C> T; Human leukocyte antigen (HLA); age at cancer diagnosis; genetic risk modifiers; personalized cancer screening
Online: 7 March 2024 (07:36:11 CET)
REVIEW
|
doi:10.20944/preprints202304.0143.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Genome stability; DNA replication; DNA repair; lagging strand DNA synthesis; Okazaki fragments; initiation; DNA polymerase α; DNA primase; CTC1-STN1-TEN1 complex; SV40 T antigen; CMG complex
Online: 10 April 2023 (04:20:27 CEST)
ARTICLE
|
doi:10.20944/preprints202107.0484.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
metformin; Natural Killer cells; Cytotoxic T lymphocytes; intercellular adhesion molecule-1 (ICAM-1); Natural Killer G2-D (NKG2D) ligands (NKG2DL); lymphocyte function-associated antigen 1 (LFA-1)
Online: 21 July 2021 (10:54:14 CEST)
REVIEW
|
doi:10.20944/preprints202105.0183.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Intravenous Immunoglobulin (IVIg); Human Leukocyte Antigen-I (HLA-1); Polyreactive mAbs; Monospecific mAbs; Shared epitopes; Immunosuppression; T-cells; B-memory cells; T-regulatory Cells; Blastogenesis, proliferation, Antibody production
Online: 10 May 2021 (12:30:03 CEST)
REVIEW
|
doi:10.20944/preprints202004.0201.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
SARS-CoV-2 Detection, SARS-CoV-2 Antibody Test, SARS-CoV-2 Antigen Test, False Negative, False Positive, Sensitivity, Specificity, Point-of-care testing (POCT), SARS-CoV-2 Mutants
Online: 25 March 2021 (15:33:14 CET)
ARTICLE
|
doi:10.20944/preprints202406.0646.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
androgen deprivation therapy (ADT); anti-tumor efficacy of hormones; estetrol (E4); High-dose estetrol (HDE4); PCombi study; testosterone (T); prostate-specific antigen (PSA); follicle-stimulating hormone (FSH); insulin-like growth factor-1 (IGF-1)
Online: 11 June 2024 (08:12:13 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1497.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
Coronavirus disease-2019 (COVID-19); Emergency Use Authorization (EUA); false negative (FN); false omission rate (RFO); point-of-care testing (POCT); prevalence boundary (PB); rapid antigen test (RAgT); repeated testing; sensitivity and specificity; tier
Online: 22 August 2023 (07:25:00 CEST)
REVIEW
|
doi:10.20944/preprints202101.0304.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Vascular Endothelial Growth Factors (VEGFs); VEGF-A; PlGF; VEGF-B; VEGF-C; VEGF-D; angiogenesis; lymphangiogenesis; CCBE1; proteases; ADAMTS3; plasmin; cathepsin D; KLK3; prostate-specific antigen (PSA); thrombin; wound healing; metastasis; proteolytic activation; vascular biology
Online: 18 January 2021 (09:05:58 CET)
ARTICLE
|
doi:10.20944/preprints201906.0028.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
autoimmunity; toll-like receptors; TLR; nucleotide-binding oligomerization domain; NOD1; major histocompatibility complex; MHC; human leukocyte antigens; HLA; proteasome; innate immunity; adaptive immunity; T cells; B cells; antibodies; microbiome; tolerance; self; non-self; antigen processing
Online: 4 June 2019 (10:21:32 CEST)
REVIEW
|
doi:10.20944/preprints202005.0244.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
COVID-19; SARS-CoV-2; antigen; monovalent; oligovalent; protein; kilodalton (kDa); Th1 response; Th2 response; B cell activation; B cell receptor (BCR); macrophage; dendritic cell; apoptosis; subcapsular sinus; immunoglobulin; interleukin; cytokine; Cytokine Storm Syndrome (CSS); allergen; immune paralysis; vaccine; polymer
Online: 14 May 2020 (15:19:53 CEST)
REVIEW
|
doi:10.20944/preprints202407.1456.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
advanced therapy medicinal products (ATMPs); chimeric antigen receptors (CAR-T cells); B acute lymphoblastic leukaemia (B-ALL); food and drug administration (FDA); systemic lupus erythematosus (SLE); idiopathic inflammatory myositis (IIM); systemic sclerosis (SS); memorial sloan kettering cancer centre (MSKCC); hematopoietic stem cell transplantation [HSCT], non-Hodgkin’ s cell lymphoma (NHCL); multiple myeloma (MM); follicular lymphoma; (FL); large B cell-lymphoma (LBCL); mantle cell lymphoma (MCL); myeloid-derived suppressor cells (MDSCs); rheumatoid arthritis (RA); immune effector cell-associated neurotoxicity syndrome (ICANS); natural killer group member D ligands (NKG2DLs); acute myelogenous leukaemia (AML)
Online: 18 July 2024 (08:03:12 CEST)