ARTICLE
|
doi:10.20944/preprints202403.1085.v1
Subject:
Biology And Life Sciences,
Agricultural Science And Agronomy
Keywords:
Solanum tuberosum; dry matter; starch; protein; ascorbic acid; carotenoids; anthocyanins; total acidity; reducing sugars; phenolic compounds; antioxidant activity; meteorological conditions of the growing season
Online: 19 March 2024 (10:17:31 CET)
REVIEW
|
doi:10.20944/preprints202308.0434.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
In silico studies; drug discovery; SARS-CoV-2; molecular docking; virtual screening; molecular dynamics simulations; drug candidates; antiviral activity; receptor-ligand complex; drug design
Online: 4 August 2023 (11:11:21 CEST)
REVIEW
|
doi:10.20944/preprints202305.2152.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cancer metabolism; anticancer activity; artificial diets; in vivo; mice; essential amino acids; non-essential amino acids; restriction; leucine; methionine; cysteine; arginine; serine; glutamine; asparagine
Online: 30 May 2023 (13:24:11 CEST)
ARTICLE
|
doi:10.20944/preprints202301.0071.v1
Subject:
Physical Sciences,
Astronomy And Astrophysics
Keywords:
Carrington event; craters; cratering; currents in plasma; electric discharge machining; geology; heliophysics; impact craters; Late Heavy Bombardment; piezoelectricity; transient crater; solar activity; Solar System
Online: 4 January 2023 (07:19:46 CET)
ARTICLE
|
doi:10.20944/preprints202111.0018.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Newcastle Disease Virus (NDV); NDV ZG1999HDS; NDV La Sota; TLT (Human macrophage cell line; Immunomodulation; Anti - Gram Positive bacteria; Anti - Gram - Negative bacteria; activity
Online: 1 November 2021 (13:01:38 CET)
ARTICLE
|
doi:10.20944/preprints202012.0414.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
galantamine; curcumin; in vivo AChE inhibition; acute toxicity in mice; antioxidant activity; malondialdehide levels; glutathione levels; brain homogenate; complete blood count; biochemical serum parameters
Online: 16 December 2020 (13:45:10 CET)
ARTICLE
|
doi:10.20944/preprints201808.0457.v1
Subject:
Engineering,
Bioengineering
Keywords:
Sleep, Office workers, office workstation, wellbeing, stress, physical activity, wearables, digital health, sleep quality index, tracking sleep quality, workstation types, accelerometry, heart rate variability
Online: 27 August 2018 (11:33:23 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1165.v1
Subject:
Biology And Life Sciences,
Ecology, Evolution, Behavior And Systematics
Keywords:
non-destructive DNA sampling; DNA collection methods; Louisiana Pigtoe; visceral swabbing; freshwater mussels; Fusconaia askewi; genotyping-by-sequencing; population genetic structure; genomic coverage; sequencing depth
Online: 16 May 2023 (14:15:33 CEST)
ARTICLE
|
doi:10.20944/preprints202202.0055.v2
Subject:
Social Sciences,
Psychology
Keywords:
Coronavirus disease 2019/COVID-19; Internet Gaming Disorder Scale9—Short form (IGDS9-SF); university students; factorial structure/psychometric properties/structural validity/validation; cultur*/collectivisti*/individualis*; invariance; gender; game type
Online: 21 March 2022 (11:04:57 CET)
ARTICLE
|
doi:10.20944/preprints201812.0236.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
bacterial toxin; cholera toxin; Escherichia coli heat-labile enterotoxin; lectin; N-acetyllactosamine binding; neutral glycosphingolipids; protein-carbohydrate interactions; surface plasmon resonance spectroscopy; X-ray crystal structure
Online: 28 January 2019 (15:23:24 CET)
REVIEW
|
doi:10.20944/preprints201707.0020.v2
Subject:
Environmental And Earth Sciences,
Geophysics And Geology
Keywords:
thin-skinned tectonics, thick-skinned tectonics, structural geology, structure of mountain ranges, fold-and-thrust belts, décollement, nappe stacking, continent-continent collision, subduction, basin inversion
Online: 27 July 2017 (10:14:40 CEST)
ARTICLE
|
doi:10.20944/preprints202401.0108.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
Activity Sensor; Fall Detection; Fall Risk Assessment; Privacy Protection; Smart Senior Care; Medical Alert System; Personal Emergency Response system; Remote Patient Monitoring, Remote Therapeutic Monitoring
Online: 3 January 2024 (10:36:31 CET)
ARTICLE
|
doi:10.20944/preprints202310.0143.v2
Subject:
Public Health And Healthcare,
Physical Therapy, Sports Therapy And Rehabilitation
Keywords:
Adolescents; Physical Activity; Muscle Power; Handgrip Strength; Dynamic Knee Val-28 gus; Screen Time; Movement Behavior; BMI; body mass index; Single Leg Drop Jump Test
Online: 6 October 2023 (08:35:34 CEST)
ARTICLE
|
doi:10.20944/preprints202306.0763.v1
Subject:
Biology And Life Sciences,
Agricultural Science And Agronomy
Keywords:
Mycogone perniciosa; Bacillus subtilis; industrial Bacillus strains; microbiocontrol; antifungal activity; producer strains; biological efficacy; multirecycled spent mushroom substrates; multirecycled SMS aqueous extracts; submerged multibiorecycled biologics
Online: 12 June 2023 (04:56:57 CEST)
ARTICLE
|
doi:10.20944/preprints202008.0056.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Cornu aspersa mucus; antimicrobial peptides; antibacterial activity; bacterial strains; Pseudomonas aureofaciens AP9; Escherichia coli NBIMCC 8785; Brevibacillus laterosporus strain BT-271; Clostridium perfringens NBIMCC 8615
Online: 3 August 2020 (00:25:22 CEST)
ARTICLE
|
doi:10.20944/preprints202410.0853.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
plant secondary metabolites; plant polyphenols; phytochemicals; DNA-binding compounds; anticancer effects; chromatin structure; linker histone depletion; type I interferon signaling; LINE1 transcription; double-stranded DNA ends
Online: 11 October 2024 (04:52:43 CEST)
ARTICLE
|
doi:10.20944/preprints202407.1499.v1
Subject:
Computer Science And Mathematics,
Discrete Mathematics And Combinatorics
Keywords:
entropy; topological indices; entropy measure; weighted entropies of Cu₂O[i,j,t] ; crystallographic structure; entropy of Cu₂O[i,j,t] ; graph theory
Online: 18 July 2024 (12:26:14 CEST)
ARTICLE
|
doi:10.20944/preprints202403.1275.v1
Subject:
Environmental And Earth Sciences,
Geochemistry And Petrology
Keywords:
“ black/fracture zone” ; tectonite-mineralized alteration lithofacies; strike-slip structure + diapirism (cryptoexplosion); Daliangzi Pb-Zn deposit; Sichuan-Yunnan-Guizhou Pb-Zn metallogenic province
Online: 22 March 2024 (03:28:20 CET)
ARTICLE
|
doi:10.20944/preprints202403.0311.v1
Subject:
Physical Sciences,
Mathematical Physics
Keywords:
Fiber bundle, phase transitions, Lie groups, homotopy,
fundamental group, Stability Theorem, Stability Lemma, Fiber Structure
Theorem, superfluid Helium
fundamental group, Stability Theorem, Stability Lemma, Fiber Structure
Theorem, superfluid Helium
Online: 6 March 2024 (10:15:05 CET)
ARTICLE
|
doi:10.20944/preprints202309.0450.v1
Subject:
Engineering,
Electrical And Electronic Engineering
Keywords:
metasurface; beam-steering; metamaterial; optimization; phase-shifting-surface; beam-steering, beam-scanning, phase-gradient surface; artificial surface; phase-correcting structure, cross-entropy method, sidelobes, grating lobes
Online: 6 September 2023 (14:48:39 CEST)
REVIEW
|
doi:10.20944/preprints202305.0503.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
RNP assembly; ribosome assembly; protein-RNA interactions; RNA folding; assembly intermediates; in vitro reconstitutions; mass spectrometry; single-molecule fluorescence microscopy; cryo-electron microscopy; RNA structure probing
Online: 8 May 2023 (10:01:55 CEST)
ARTICLE
|
doi:10.20944/preprints202212.0530.v1
Subject:
Physical Sciences,
Atomic And Molecular Physics
Keywords:
generalized relativistic pseudopotentials; molecular integrals; Gaussian basis functions; relativistic coupled cluster theory; excited states; heavy-element compounds; high-precision electronic structure modeling; thorium oxide; uranium dioxide.
Online: 28 December 2022 (07:57:51 CET)
ARTICLE
Subject:
Computer Science And Mathematics,
Computer Science
Keywords:
photogrammetry; metrology; underwater 3D reconstruction; structure-from-motion; navigation fusion; multi-objective BA; laser scalers; Monte-Carlo simulation; uncertainty estimation; scale drift evaluation; laser spot detection
Online: 15 July 2019 (05:22:16 CEST)
ARTICLE
|
doi:10.20944/preprints202401.0050.v1
Subject:
Environmental And Earth Sciences,
Atmospheric Science And Meteorology
Keywords:
sea surface temperature (SST); El-Nino - Southern Oscillation (ENSO); long-term variability; numerical simulation; reanalysis data; stratospheric ozone; stratosphere polar vortex (SPV); residual circulation; wave activity
Online: 2 January 2024 (07:57:50 CET)
ARTICLE
|
doi:10.20944/preprints201801.0022.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
Phaleria macrocarpa; extraction; free radical scavenging activity (DPPH); ferric ion reducing power assay (FRAP); total phenolic content (TPC); total flavonoid content (TFC); response surface methodology (RSM)
Online: 3 January 2018 (10:15:16 CET)
ARTICLE
|
doi:10.20944/preprints202405.0932.v1
Subject:
Physical Sciences,
Theoretical Physics
Keywords:
nucleon g-factor; Möbius band; fine-structure constant; quark charges; quark masses; W boson mass; proton charge radius; energetic causal sets; circular Unruh effect; intrinsic charm quarks
Online: 14 May 2024 (09:57:36 CEST)
ARTICLE
|
doi:10.20944/preprints201909.0001.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
treating filler complications; hyaluronidase; red king crab; hepatopancreas; hyaluronic acid (HA); hyaluronidase activity; turbidimetric method; atomic force microscopy (AFM); nuclear magnetic resonance (NMR); Revofil Ultra filler; Hyaluform deep filler; Lydase; Liporase
Online: 14 October 2019 (15:42:23 CEST)
REVIEW
|
doi:10.20944/preprints201809.0281.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
axon guidance; growth cone; cytoskeleton; caspases; apoptosis; signal integration; basal level of caspase activity; death associated inhibitor of apoptosis; axon branching; Netrin; DCC; frazzled; slit; robo; Drosophila
Online: 16 September 2018 (09:43:52 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0157.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Dye decolorizing-type peroxidase; heme peroxidases; lignin degradation; Dictyostelium discoideum; B-type DyP; electron paramagnetic resonance (EPR) spectroscopy; compound I; enzyme kinetics; crystal structure; long-range electron transfer
Online: 3 June 2021 (12:12:22 CEST)
ARTICLE
|
doi:10.20944/preprints202103.0640.v1
Subject:
Computer Science And Mathematics,
Algebra And Number Theory
Keywords:
Databases; database administration; database management systems; counting; storage; structure; search; No SQL; SQL; Oracle; relational databases; non-relational databases; magnetic tapes; punched tapes; relational model; Datamining; BigData; Datawarehouse
Online: 25 March 2021 (16:05:52 CET)
ARTICLE
|
doi:10.20944/preprints202012.0205.v1
Subject:
Engineering,
Automotive Engineering
Keywords:
History of technology; Computer Vision; Photogrammetry; Endoscopy; Computed Tomography; Convolutional Neural Networks; Structure-from-Motion; Dense Image Matching; Data Fusion; Sensor Fusion; Digital Twin; Navigation Instruments; Inertial Sensors
Online: 8 December 2020 (16:18:53 CET)
BRIEF REPORT
|
doi:10.20944/preprints202106.0341.v2
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Impact of COVID on TB; TB Notification in India; Integrated TB COVID Activity; Threats and Opportunity during COVID; Initiatives to improve TB Surveillance; TB Surveillance during COVID Pandemic
Online: 22 June 2021 (14:05:04 CEST)
REVIEW
|
doi:10.20944/preprints202308.1948.v2
Subject:
Physical Sciences,
Astronomy And Astrophysics
Keywords:
Sun: corona; Sun: radio radiation; acceleration of particles; magnetic reconnection; Sun: Radiation mechanisms: non-thermal; Sun: Meter-Wavelengths and Longer; Sun: activity; Sun: Flares; Sun: Ejections; Sun: magnetic fields
Online: 19 September 2023 (03:38:47 CEST)
ARTICLE
|
doi:10.20944/preprints202003.0012.v1
Subject:
Engineering,
Architecture, Building And Construction
Keywords:
Building Information Modelling (BIM); Life-Cycle Assessment (LCA); Building process; Level of Development (LOD); Embodied environmental impacts; Greenhouse Gas emissions (GHG); LCA databases; LCA values; LCA benchmarks; cost estimation structure
Online: 1 March 2020 (13:16:52 CET)
ARTICLE
|
doi:10.20944/preprints202407.1427.v1
Subject:
Chemistry And Materials Science,
Materials Science And Technology
Keywords:
Hamieh thermal model; Dispersive and polar free energy; thermal conductivity; London dispersive surface energy; Lewis’ s acid– base parameters; polar acid-base surface energy; intermolecular separation distance; supramolecular structure
Online: 17 July 2024 (12:46:00 CEST)
REVIEW
|
doi:10.20944/preprints202301.0004.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
Baroenzymology; Cryoenzymology; Intrinsic disorder; Intrinsically disordered proteins; Macromolecular crowding; Nanomaterials; Partially folded intermediate; Protein denaturation; Protein engineering; Protein flexibility; Protein folding; Protein function; Protein stability; Protein structure; Protein refolding; Protein unfolding
Online: 3 January 2023 (06:48:30 CET)
HYPOTHESIS
|
doi:10.20944/preprints202410.0352.v1
Subject:
Physical Sciences,
Theoretical Physics
Keywords:
Special relativity; General relativity; Bohr atomic model; the fine-structure constant; photon energy; energy of the total photon; Electron wave by de Broglie; Gravity constant; Quantum jump and Cosmic constants of nature
Online: 4 October 2024 (20:50:24 CEST)
HYPOTHESIS
|
doi:10.20944/preprints202409.1598.v2
Subject:
Physical Sciences,
Theoretical Physics
Keywords:
special relativity; general relativity; Bohr atomic model; the fine-structure constant; photon energy; energy of the total photon; electron wave by de Broglie; gravity constant; quantum jump and cosmic constants of nature
Online: 30 September 2024 (09:09:31 CEST)
REVIEW
|
doi:10.20944/preprints202408.0868.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Comparative Analysis; Cranial Morphology; Allosaurus; Feeding Mechanics; Theropod Dinosaurs; Jurassic Period; Skull Structure; Predatory Behavior; Fossil Anatomy; Dinosaur Feeding Strategies; Morphological Adaptations; Ecological Role; Cranial Kinesis; Bite Force; Sensory Functions; Biomechanics; Pathologies; Evolutionary Insights
Online: 13 August 2024 (08:56:01 CEST)
ARTICLE
|
doi:10.20944/preprints202206.0256.v1
Subject:
Physical Sciences,
Particle And Field Physics
Keywords:
unified theory of force; Gravitation; Electromagnetic force; Weak force; Strong force; Inverse square law; Galaxy rotation curve; The origin of magnetic field; Charged particle radiation; Maxwell displacement current; Black hole structure; Radiation effect of moving magnet
Online: 20 June 2022 (03:03:59 CEST)
ARTICLE
|
doi:10.20944/preprints202010.0294.v1
Subject:
Physical Sciences,
Condensed Matter Physics
Keywords:
crystallization; crystal, hexagonal close packed, face center cubic, body center cubic, hexagonal crystal, square lattice, honeycomb lattice, trigonal lattice, Monte Carlo, crystallography, crystallographic elements, symmetry, entropy, hard sphere, polymer, square well, local structure, dense packing, thin film
Online: 14 October 2020 (10:05:22 CEST)
REVIEW
|
doi:10.20944/preprints202405.0601.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Data science; Big data; Data mining; Bioinformatics; Chemometric; Medicinal chemistry; Targets; Knowledge discovery; Artificial intelligence, Machine learning, Deep learning; Data integration; Metadata, Database; QSAR; Collaborative drug discovery; Structure-based drug design; Ligand-based drug discovery; Clinical trials; Product development.
Online: 10 May 2024 (10:15:20 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0729.v1
Subject:
Medicine And Pharmacology,
Complementary And Alternative Medicine
Keywords:
hormonal replacement therapy (HRT); mindfulness-based stress reduction (MBSR); Risk reducing salpingo-oophorectomy (RRSO); Breast Cancer Associated Susceptibility Protein Type 1/2 (BRCA1/2) mutations; Menopause rating scale (MRS); menopause/perimenopause/postmenopausal; psychological symptoms; physical activity/exercise; breast cancer
Online: 12 June 2024 (00:04:00 CEST)
REVIEW
|
doi:10.20944/preprints202407.2089.v2
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Gigantism in theropods; Giganotosaurus carolinii; Body size evolution; Theropod morphology; Ecological roles; Apex predator; Skeletal morphology; Comparative anatomy; Paleoenvironmental data; Evolutionary pressures; Biological constraints; Physiological adaptations; Ecological adaptations; Cretaceous environment; Prey dynamics; Interspecies interactions; Ecosystem structure; Paleontological implications; Theropod behavior; Paleoecological landscape
Online: 7 August 2024 (23:13:43 CEST)
REVIEW
|
doi:10.20944/preprints202110.0453.v5
Subject:
Physical Sciences,
Nuclear And High Energy Physics
Keywords:
Foundation of physics; Planck scale physics; Matter; space; time; Consciousness; Life; informational physics; fundamental physical problems; cosmology; quantum mechanics; relativity theories; Standard Model; particles; antiparticles; fundamental Nature forces; EM force; Gravity; Nuclear force; quantum gravity; equivalence of inertial and gravitational masses; fine structure constant; Lorentz transformations; experimental testing
Online: 30 July 2024 (11:03:36 CEST)
ARTICLE
|
doi:10.20944/preprints202208.0176.v1
Subject:
Social Sciences,
Psychology
Keywords:
psychological distress/anxiety/depression; dementia; Alzheimer’s disease; Parkinson’s disease; short form of the Depression Anxiety Stress Scale 21; Depression Anxiety Stress Scale 8-items; factor structure; psychometric properties; structural validity; validation; measurement invariance; old age/elders/elderly; informal; family caregivers; spouse; adult children
Online: 9 August 2022 (08:44:11 CEST)
COMMUNICATION
|
doi:10.20944/preprints202203.0377.v1
Subject:
Chemistry And Materials Science,
Organic Chemistry
Keywords:
p-nitrophenyl hydrazone; solvent-free; green synthesis; p-nitrophenyl hydrazine; mechanochemistry; dichloro p-nitrophenyl hydrazone; methoxy p-nitrophenyl hydrazone; solvent-based; spectroscopy; elucidation.; p-Nitrophenyl hydrazone; solvent-free; green synthesis; p-Nitrophenyl hydrazine; mechanochemistry; dichloro and methoxy p-Nitrophenyl hydrazone; solvent-based; structure elucidation; spectroscopy
Online: 29 March 2022 (08:53:22 CEST)
ARTICLE
|
doi:10.20944/preprints202109.0014.v1
Subject:
Social Sciences,
Psychology
Keywords:
Coronavirus disease 2019/COVID-19; Depression Anxiety Stress Scales-21/DASS-21; DASS-8; shortened version*; shorter version* of the DASS-21; psychiatric disorders; factorial structure/psychometric properties/structural validity/validation; measurement invariance/multigroup analysis; psychological distress; discriminant validity; item coverage; good predictive validity
Online: 1 September 2021 (12:15:27 CEST)
ARTICLE
Subject:
Physical Sciences,
Mathematical Physics
Keywords:
quantum mechanics; algebraic geometry; commutative algebra; Grönber basis; primary ideal decomposition; eigenvalue problem in quantum mechanics; molecular orbital theory; quantum chemistry; first principles electronic structure calculation; symbolic computation; symbolic-numeric solving; Hartree-Fock theory; molecular integral; Taylor series; polynomial approximation; algebraic molecular orbital equation
Online: 26 December 2019 (02:17:44 CET)
ARTICLE
|
doi:10.20944/preprints202301.0489.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
multidrug resistance; MDR; EPB (Xenorhabdus; (X. budapestensis; X. szentirmaii; X. innexii); and Photorhabdus) species); CFCM (cell-free conditioned media); NR-AMP (non-ribosomal-templated antimicrobial peptides); anti-microbial; (anti-bacterial; - anti-coccidial; -anti-protist; - activity; cytotoxicity; in vitro; in situ (local) bioavailablity; XENOFOOD; allometry
Online: 27 January 2023 (06:21:56 CET)
HYPOTHESIS
|
doi:10.20944/preprints202406.0674.v6
Subject:
Physical Sciences,
Theoretical Physics
Keywords:
Hyper-Torus Universe Model (HTUM); 4-dimensional toroidal structure (4DTS); quantum mechanics; cosmology; consciousness; quantum gravity; unified field theory; quantum cosmology; theoretical physics; topology; manifold theory; cyclic universe; wave function collapse; quantum entanglement; event horizon; holographic principle; quantum measurement; dark energy; dark matter; Topological Vacuum Energy Modulator (TVEM); cosmological constant problem; Lambda-CDM model; multiverse; string theory; loop quantum gravity; emergent spacetime; quantum foundations; philosophy of physics; cosmic microwave background (CMB); CMB power spectrum; acoustic peaks; large-scale structure; angular power spectrum; cosmic topology; nonlinear probabilistic phenomena; universal self-observation; mind-matter relationship; quantum state actualization
Online: 24 July 2024 (02:20:04 CEST)
ARTICLE
|
doi:10.20944/preprints202410.0760.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Immunoglobulins; antibodies; immune response; antibody structure; immunoglobulin function; therapeutic antibodies; immunotherapy; antigen recognition; immune system; B cells; immunoglobulin classification; IgG; IgA; IgM; IgE; IgD; monoclonal antibodies; polyclonal antibodies; antibody engineering; autoimmune diseases; antibody production; immune regulation; immunological memory; antigen-antibody interaction; clinical immunology; molecular immunology; vaccine development; passive immunity; biopharmaceuticals; antibody-mediated immunity; infectious diseases; cancer immunotherapy; inflammation control; immunoglobulin deficiencies; diagnostic antibodies; therapeutic applications in immunology
Online: 10 October 2024 (09:08:58 CEST)
ARTICLE
|
doi:10.20944/preprints201810.0088.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
There are many molecules used as drug carrier. TUD-1 is a newly synthesized mesoporous silica (SM) molecule possess two important features; consists of mesoporous so it is very suitable to be drug carrier in addition to that it has the ability to induce apoptosis in cancer cells. However, the effect of TUD-1 appears to act as cell death inducer, regardless of whether it is necrosis or apoptosis. Unfortunately, recent studies indicate that a proportion of cells undergo necrosis rather than apoptosis, which limits the use of TUD-1 as a secure treatment. On the other hand, lithium considered as necrosis inhibitor element. Hence, current study based on the idea of production a new Li/TUD-1 by incorporated mesoporous silica (TUD-1 type) with lithium in order to produce a new compound that has the ability to activate apoptosis by mesoporous silica (TUD-1 type) and at the same time can inhibit the activity of necrosis by lithium. Herein, lithium was incorporated in TUD-1 mesoporous silica by
Online: 4 October 2018 (15:54:02 CEST)