ARTICLE
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doi:10.20944/preprints202102.0397.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
pyrazolopyrimidinone; hydrazide-hydrazone; antitumor lead compound; cytotoxic activity; antiproliferative activity; molecular docking; epidermal growth factor receptor; G-quadruplex DNA; KRAS; circular dichroism
Online: 17 February 2021 (14:05:44 CET)
REVIEW
|
doi:10.20944/preprints202407.2158.v2
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
immune system; natural immunity; adaptive immunity; interferon system; plasmacytoid dendritic cells; lymphocytes; viruses; bacteria; fungi; DNA; RNA; evolution; molecular self camouflaging; innovation; vaccines
Online: 2 August 2024 (11:36:10 CEST)
ARTICLE
|
doi:10.20944/preprints202407.1301.v1
Subject:
Physical Sciences,
Thermodynamics
Keywords:
homogeneous bubble nucleation; cavitation; classical nucleation theory (CNT); nucleation free energy; critical nucleus; molecular dynamics (MD) simulation; Jarzynski equality; stochastic thermodynamics; surface tension
Online: 16 July 2024 (08:56:59 CEST)
ARTICLE
|
doi:10.20944/preprints202407.0786.v1
Subject:
Chemistry And Materials Science,
Physical Chemistry
Keywords:
Monte Carlo; Athermal Mixture; Crystallization; Entropy-driven Phase Transition; Colloids; Polymer; Face Centered Cubic; Hexagonal Close Packed, Molecular Simulation; Dense Packing; Hard Sphere
Online: 10 July 2024 (04:15:20 CEST)
ARTICLE
|
doi:10.20944/preprints202405.1831.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Lippia adoensis; Plasmodium falciparum; Leishmania donovani; Trypanosoma brucei; molecular networking; LC-MS analysis
Online: 28 May 2024 (11:28:34 CEST)
ARTICLE
|
doi:10.20944/preprints202401.0219.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
CRE; ESBL; extended spectrum beta lactamase; non-carbapenemase-producing; ertapenem-resistant; meropenem-susceptible; porin loss; outer-membrane protein; mobile genetic elements; molecular epidemiology
Online: 3 January 2024 (09:43:24 CET)
ARTICLE
|
doi:10.20944/preprints202311.0480.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Alzheimer's disease (AD); 4-amino-2,3-polymethylenequinolines; butylated hydroxytoluene (BHT); acetylcholinesterase (AChE); butyrylcholinesterase (BChE); antioxidants; ADMET; β-amyloid; molecular docking; quantum-chemical calculations
Online: 7 November 2023 (15:47:06 CET)
ARTICLE
|
doi:10.20944/preprints202207.0058.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
human interferon gamma; human interferon gamma receptor; receptor binding; heparan sulfate; co-receptor; molecular dynamics simulations; sodium chlorate; kynurenine antiproliferative assays; hIFNγ signalling
Online: 5 July 2022 (04:43:05 CEST)
ARTICLE
|
doi:10.20944/preprints202101.0441.v1
Subject:
Computer Science And Mathematics,
Algebra And Number Theory
Keywords:
Quantum Similarity; DNA; Molecular Biology; Meticodes; response variance; object set reference; Bioinformatics; Computational Physics; Computational Models; Mathematics; Probability; Statistics; Comparative Modeling; Biostatics; Biostatistics
Online: 22 January 2021 (11:35:18 CET)
ARTICLE
|
doi:10.20944/preprints201811.0334.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
human African trypanosomiasis; pteridine reductase 1; PTR1; DHFR; antifolates; anti-trypanosomal agents; molecular dynamics; dynamic residue network analysis; binding free energy; isobologram assay
Online: 14 November 2018 (10:39:01 CET)
REVIEW
|
doi:10.20944/preprints202408.0930.v1
Subject:
Biology And Life Sciences,
Insect Science
Keywords:
Xyleborus beetles; ambrosia beetles; forest pests; agricultural impact; pest management; biological control; integrated pest management (IPM); molecular genetics; ecological impact; economic impact
Online: 13 August 2024 (14:36:47 CEST)
ARTICLE
|
doi:10.20944/preprints202405.1676.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
Molecular Imprinting Polymer-MIP; Molecularly Imprinted Nanofibers-MINF; Electrospinning; PVP-PAA-MWCNT composite sensor; BVOCs; Terpenes; Limonene selective detection; Precision agriculture; Environmental VOCs monitoring
Online: 27 May 2024 (06:54:54 CEST)
ARTICLE
|
doi:10.20944/preprints202401.1548.v1
Subject:
Chemistry And Materials Science,
Chemical Engineering
Keywords:
deformation polarizability; ionization energy; London dispersive free energy; polar energy of adsorption; Lewis’ s acid-base components of surface energy; molecular separation distance
Online: 22 January 2024 (09:30:50 CET)
REVIEW
|
doi:10.20944/preprints202311.0716.v1
Subject:
Medicine And Pharmacology,
Obstetrics And Gynaecology
Keywords:
borderline ovarian tumors; molecular features; mutations; genetic mutations; BRAF; KRAS; NRAS; ARID1A; CADM1; PIK3CA; CHEK2; CLAUDIN-1; ERBB2; loss of heterozygosity; PTEN; microsatellite instability
Online: 13 November 2023 (08:32:29 CET)
ARTICLE
|
doi:10.20944/preprints202012.0119.v2
Subject:
Environmental And Earth Sciences,
Atmospheric Science And Meteorology
Keywords:
Pedostructure; Systemic modelling; Systemic variables, hydro-thermodynamic equilibrium; Gibbs free energy; Fundamental thermodynamic variables; molecular, real and Eulerian fluxes, hydric conductivity of the pedostructure.
Online: 29 December 2020 (17:15:56 CET)
REVIEW
|
doi:10.20944/preprints202310.1723.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
molecular tweezers; cation-pi interactions; intrinsic disorder, protein-protein interactions; hydrophobic interaction chromatography, monoclonal antibody production; protein aggregation; protein refolding; arginine methyltransferases; post-translational modification
Online: 27 October 2023 (05:51:26 CEST)
ARTICLE
|
doi:10.20944/preprints202303.0132.v1
Subject:
Biology And Life Sciences,
Ecology, Evolution, Behavior And Systematics
Keywords:
Toxoplasma gondii; rodents; rodent-borne diseases; environment contamination; biomonitoring; wildlife; molecular detection; PCR assay; nested-PCR assay prevalence; serological detection; agglutination test; ELISA method; seroprevalence
Online: 7 March 2023 (09:38:21 CET)
ARTICLE
|
doi:10.20944/preprints202209.0170.v1
Subject:
Physical Sciences,
Atomic And Molecular Physics
Keywords:
n/a; Hard Sphere; Crystallization; Entropy-driven phenomena; packing, polymer, molecular simulation, phase transition, face centered-cubic, hexagonal close packed; random walk; colloids; crystal perfection
Online: 13 September 2022 (10:16:17 CEST)
ARTICLE
|
doi:10.20944/preprints202207.0339.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
Infectious disease testing; public health preparedness; point-of-care testing (POCT); molecular diagnostics; therapeutic turnaround time (TTAT); acute medical challenges; geographic information systems; antimicrobial stewardship
Online: 22 July 2022 (13:13:53 CEST)
ARTICLE
|
doi:10.20944/preprints202405.1511.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Breast cancer; network pharmacology; text mining; drug therapy; genes; pathway analysis; biological process; protein-protein interaction; degree and betweenness; molecular docking; meristematic cells; anti-mitotic; hepatotoxicity
Online: 23 May 2024 (07:34:57 CEST)
ARTICLE
|
doi:10.20944/preprints202309.1706.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
isoxazolidine derivatives; 1,3-dipolar cycloaddition; α-aryl-N-methyl nitrones; Density Functional Theory (DFT); Electron Localization Function (ELF); CDFT indices; docking; molecular dynamics; EGFR; binding energy
Online: 26 September 2023 (04:37:56 CEST)
ARTICLE
|
doi:10.20944/preprints202212.0530.v1
Subject:
Physical Sciences,
Atomic And Molecular Physics
Keywords:
generalized relativistic pseudopotentials; molecular integrals; Gaussian basis functions; relativistic coupled cluster theory; excited states; heavy-element compounds; high-precision electronic structure modeling; thorium oxide; uranium dioxide.
Online: 28 December 2022 (07:57:51 CET)
REVIEW
|
doi:10.20944/preprints202402.1123.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Mycobacterium tuberculosis; multidrug-resistant; extensively drug-resistant; diagnostic methods; point-of-care; phenotypic methods; molecular methods; drug resistance detection; rapid test
Online: 20 February 2024 (11:46:19 CET)
REVIEW
|
doi:10.20944/preprints202201.0366.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cell-free DNA; liquid biopsy; cancer; next-generation sequencing (NGS); minimal residual disease; measurable residual disease; molecular residual disease (MRD); leukemia; lymphoma; myeloma; myeloproliferative neoplasms; myelodysplastic syndrome
Online: 25 January 2022 (08:13:24 CET)
ARTICLE
|
doi:10.20944/preprints202002.0097.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Protein structure and dynamics; Molecular structure and modeling; Protein and macromolecules; Computational methods and bioinformatics; Computer-based teaching tools; Learning materials and teaching tools; Multimedia teaching tools
Online: 7 February 2020 (11:42:09 CET)
REVIEW
|
doi:10.20944/preprints202309.1260.v1
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
PANDAS; Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections; PANDAS syndrome; neuropsychiatric disorder; streptococci; molecular mimicry; CaM kinase; striatal cholinergic interneurons; obsessive-compulsive disorder; streptococcal infection; tic; tics
Online: 19 September 2023 (07:09:19 CEST)
ARTICLE
|
doi:10.20944/preprints202402.0574.v1
Subject:
Physical Sciences,
Condensed Matter Physics
Keywords:
molecular dynamics simulation; quantum-chemical semiempirical methods, Landau-Ginzburg-Devonshire theory; polarization; nanoscale ferroelectrics; polymers thin films; PVDF; PVDF-TrFE; homogeneous switching; switching time; coercive field; graphene; composites; heterostructures
Online: 9 February 2024 (10:57:21 CET)
REVIEW
|
doi:10.20944/preprints202401.0312.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Dioxygen; Molecular oxygen; Baeyer-Villiger monooxygenase; 2,5-diketocamphane 1,2-monooxygenase; flavin-dependent two-component monooxygenase; flavin reductase; putidaredoxin reductase; CAM plasmid; Pseudomonas putida ATCC 17453
Online: 4 January 2024 (07:12:14 CET)
ARTICLE
|
doi:10.20944/preprints202301.0553.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Cowpea chlorotic mottle virus; purification; affinity extraction; affinity chromatography, CCMV-binding peptide; virus-like particles; VLP, plant virus, nanotechnology, nanoparticles; virus production; safety issues; ultracentrifugation-free protocol; molecular dynamics
Online: 30 January 2023 (10:09:14 CET)
REVIEW
|
doi:10.20944/preprints202407.1534.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
lymphoma; B‐cell; hematologic neoplasms; bruton tyrosine kinase; protein kinase inhibitors; drug resistance; neoplasm; ibrutinib; pirtobrutinib; molecular targeted therapy; chronic lymphocytic leukemia; hematopoietic stem cell transplantation; covalent inhibitors; protein degradation
Online: 18 July 2024 (17:24:05 CEST)
REVIEW
|
doi:10.20944/preprints202310.0414.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
primate evolution genetics; noncoding genome; immunogenetics; neurogenetics; neurobiology; cell biology; molecular biology; neurological diseases; cardiovascular diseases; brain-immune system interactions; nucleic acid therapeutics; RNA interference; AAV vectors; blood-brain-barrier
Online: 8 October 2023 (07:20:59 CEST)
ARTICLE
|
doi:10.20944/preprints202404.0812.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
Helicobacter pylori; antibiotic resistance; methods for determining H. pylori resistance; molecular genetic diagnostics; phenotypic methods for determining antibiotic resistance; geographical distribution of H. pylori antibiotic resistance
Online: 12 April 2024 (03:53:47 CEST)
REVIEW
|
doi:10.20944/preprints202209.0139.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Bacillus Calmette-Guérin (BCG); tuberculosis; Non-tuberculous mycobacteria (NTM); nonspecific effects; Trained Immunity; Type 1 Diabetes; Multiple Sclerosis; Parkinson’s Disease; Alzheimer’s disease; Mycobacterium avium ss. paratuberculosis (MAP); molecular mimicry; Global Burden of Disease
Online: 12 September 2022 (09:36:16 CEST)
REVIEW
|
doi:10.20944/preprints202210.0248.v1
Subject:
Biology And Life Sciences,
Aging
Keywords:
Trade-off of survival for reproduction; natural selection of aging; regulatory redundancy; aging’s individual benefit; regulatory molecular biology; Darwin’s dilemma; aging-reproduction trade-off; aging declines force of selection; master gene; holistic regulatory mechanism
Online: 18 October 2022 (04:36:09 CEST)
ARTICLE
|
doi:10.20944/preprints202301.0026.v1
Subject:
Chemistry And Materials Science,
Polymers And Plastics
Keywords:
semi-flexible polymers; hard sphere; athermal chain; Monte Carlo; molecular simulation; crystallization; packing; phase transition; order parameter; liquid crystal; nematic order; oblate mesogen; prolate mesogen; face centered cubic; hexagonal close packed; bending angle; freely-jointed model
Online: 3 January 2023 (09:30:22 CET)
REVIEW
|
doi:10.20944/preprints202401.0124.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Phage display; landscape phage; molecular evolution; affinity selection; recombinant antibodies, PC; prostate specific antigen (PSA); prostate-specific matrix antigen (PSMA); Enzyme-linked immunosorbent assay (ELISA); phage ELISA; phage capture assay; electrochemical biosensor; total prostate-specific antigen (t-PSA); free prostate-specific antigen (F-PSA); electrochemical impedance spectroscopy; label-free immunosensor
Online: 3 January 2024 (10:36:52 CET)
ARTICLE
|
doi:10.20944/preprints202006.0165.v2
Subject:
Biology And Life Sciences,
Virology
Keywords:
Conserved signature indels (CSIs) specific for SARS and SARS-CoV-2-related viruses. Molecular markers distinguishing different clades of Sarbecovirus, Evolutionary relationships between SARS and SARS-CoV-2-related viruses, Origin of SARS-CoV-2 and Pangolin CoV_MP789 viruses, Novel sequence and structural features of spike and nucleocapsid proteins. Genetic recombination.
Online: 26 August 2020 (10:17:16 CEST)