ARTICLE
|
doi:10.20944/preprints202305.1006.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Melanoma; drug discovery; spliceosomal inhibition; BRAF; cell line xenograft; organ histopathology
Online: 15 May 2023 (09:19:54 CEST)
ARTICLE
|
doi:10.20944/preprints202305.0332.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
Ophthalmology; Toxicology Pharmacology and therapeutics; Drug interactions; Pharma-cology and therapeutics
Online: 5 May 2023 (08:56:37 CEST)
ARTICLE
|
doi:10.20944/preprints202302.0100.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
mesenchymal stem cell; drug delivery; surface modification; electrostatic interaction; magnetic liposome
Online: 6 February 2023 (10:07:55 CET)
REVIEW
|
doi:10.20944/preprints202212.0581.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Japanese encephalitis (JE); Japanese Encephalitis Virus (JEV); Therapeutics; Vaccine; Antiviral; Drug
Online: 30 December 2022 (09:57:27 CET)
BRIEF REPORT
|
doi:10.20944/preprints202211.0063.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
melanoma; drug discovery; spliceosomal inhibition; acute toxicity; blood chemistry; organ histopathology
Online: 3 November 2022 (01:43:05 CET)
ARTICLE
|
doi:10.20944/preprints202210.0219.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Endometriosis; Orbignya speciosa; Copaifera lansgdorffii nanoemulsion; self-nanoemulsifying drug delivery system
Online: 17 October 2022 (02:07:50 CEST)
COMMUNICATION
|
doi:10.20944/preprints202208.0039.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Echovirus; enterovirus; broad-spectrum antiviral agent; antiviral drug combination; antiviral strategy
Online: 2 August 2022 (05:01:21 CEST)
REVIEW
|
doi:10.20944/preprints202201.0117.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
G protein-coupled receptor; mouse models; skin cancer; UVR; drug; network
Online: 10 January 2022 (13:41:08 CET)
ARTICLE
|
doi:10.20944/preprints202110.0021.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
chitosan; dexketoprofen trometamol; drug delivery; gelatin; NSAIDs; personalized medicine; smart polymers
Online: 1 October 2021 (13:53:53 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Otolaryngology
Keywords:
Drug-induced hearing loss; cochlea; outer hair cells; hearing protection; SIRT3
Online: 9 August 2021 (07:50:36 CEST)
ARTICLE
|
doi:10.20944/preprints202107.0246.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
influenza virus; virus-host interaction; commonly prescribed drugs; drug adverse reaction
Online: 12 July 2021 (11:37:07 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0385.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
antibiotic resistance; antimicrobial susceptibility testing; novel diagnostics; polymicrobial; sputum; drug resistant
Online: 14 April 2021 (14:21:15 CEST)
ARTICLE
|
doi:10.20944/preprints202012.0534.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
creatinine; vancomycin; amikacin; renal impairment; acute kidney injury; adverse drug reaction
Online: 21 December 2020 (15:42:59 CET)
ARTICLE
|
doi:10.20944/preprints202012.0358.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
Antitumor agents; Fluorescence lifetime imaging; Medicinal chemistry; Metabolic drug; Mitochondrial carrier
Online: 15 December 2020 (08:35:30 CET)
ARTICLE
|
doi:10.20944/preprints202009.0205.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Franz-Bampa; BCS drugs; biomimetic membrane; Franz cell; passive drug transport
Online: 9 September 2020 (10:25:54 CEST)
REVIEW
|
doi:10.20944/preprints202008.0729.v2
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
p53; p73; MDM2; MDMX; tumor suppressor; drug repurposing; aspirin; protoporphyrin IX; verteporfin
Online: 17 September 2020 (07:23:37 CEST)
REVIEW
|
doi:10.20944/preprints202007.0478.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Bioinformatics; Drug Design; Small Organic Molecule; Target identification; Web-based Server
Online: 25 July 2020 (17:50:30 CEST)
ARTICLE
|
doi:10.20944/preprints202006.0358.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Enzyme inhibition; Secondary Metabolites; In-silico Analysis; Molecular docking; Drug candidates
Online: 30 June 2020 (08:11:28 CEST)
HYPOTHESIS
|
doi:10.20944/preprints202004.0215.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
endocanabinoid system; sleep deprivation; animal models; psychosis-like symptoms; drug development
Online: 14 April 2020 (06:28:23 CEST)
REVIEW
|
doi:10.20944/preprints202004.0012.v1
Subject:
Chemistry And Materials Science,
Theoretical Chemistry
Keywords:
chemoinformatics; chemical space; database; LANaPD; molecular diversity; drug discovery; natural sources
Online: 2 April 2020 (04:47:13 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
humans; infection control; therapy; coronavirus; immunoglobulins; drug therapy; therapeutic use; corticosteroid
Online: 8 March 2020 (17:04:19 CET)
REVIEW
Subject:
Medicine And Pharmacology,
Anesthesiology And Pain Medicine
Keywords:
pharmacology; drug development; sodium channel; potassium channel; TRP channel; HCN channels
Online: 8 August 2019 (12:31:26 CEST)
ARTICLE
|
doi:10.20944/preprints201810.0236.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
essential oils; drug resistant microorganisms; antimicrobial activity; antifungal activity; medicinal plants
Online: 11 October 2018 (11:51:16 CEST)
ARTICLE
|
doi:10.20944/preprints201809.0558.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
Alginate, Chitosan, Layer-by-layer, Magnetic nanoparticles, Drug delivery, Cancer, Curcumin
Online: 28 September 2018 (09:26:48 CEST)
HYPOTHESIS
|
doi:10.20944/preprints201808.0127.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Big Data, Systems Models, Cancer metabolism, Cancer personalized treatment, Drug Discovery.
Online: 6 August 2018 (15:09:15 CEST)
ARTICLE
|
doi:10.20944/preprints201806.0192.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
β4-galactosyltransferase 4; transcriptional mechanism; sensor cells; colon cancer; drug screening
Online: 12 June 2018 (12:51:07 CEST)
REVIEW
|
doi:10.20944/preprints201805.0378.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
annexins; inflammation; wound healing; host-pathogen interplay; drug target; translational research
Online: 27 May 2018 (11:32:34 CEST)
ARTICLE
|
doi:10.20944/preprints201711.0090.v1
Subject:
Medicine And Pharmacology,
Dentistry And Oral Surgery
Keywords:
drug delivery; dentine; diffusion; bio-active molecules; CFD; μ-LIF; microfluidics
Online: 14 November 2017 (10:15:29 CET)
REVIEW
|
doi:10.20944/preprints202209.0201.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
ligand-based pharmacophores; structure-based pharmacophores; virtual screening; drug design; machine learning; molecular dynamics; de novo design
Online: 14 September 2022 (09:10:58 CEST)
REVIEW
|
doi:10.20944/preprints202312.0983.v1
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
concussion; mild traumatic brain injury (mTBI); central sensitization; sports-related concussion; peripheral sensitization; glymphatic system; neuroinflammation; pain catastrophizing.
Online: 13 December 2023 (11:33:11 CET)
COMMUNICATION
|
doi:10.20944/preprints202011.0720.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Papillary thyroid cancer; noninvasive follicular thyroid neoplasm with papillary-like nuclear features; follicular adenoma; telomere-related genomic instability
Online: 30 November 2020 (11:37:22 CET)
ARTICLE
|
doi:10.20944/preprints202007.0603.v1
Subject:
Engineering,
Civil Engineering
Keywords:
regional flood frequency analysis; flood-related attribute; region of influence; flood region revision process; Canadian annual maximum flow
Online: 25 July 2020 (11:12:32 CEST)
ARTICLE
|
doi:10.20944/preprints201811.0609.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
immune checkpoint inhibitors; immune-related adverse events (irAEs); tolerance; ipilimumab; nivolumab; interleukin-2; hyperthermia; low-dose-combination therapy
Online: 28 November 2018 (10:23:31 CET)
ARTICLE
|
doi:10.20944/preprints202308.1963.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
Core-shell nanogels; nonlinear PEG; anisole; biocompatible; thermo-responsive; curcumin stability, high loading capacity; drug delivery
Online: 30 August 2023 (04:08:45 CEST)
ARTICLE
|
doi:10.20944/preprints202201.0030.v1
Subject:
Engineering,
Civil Engineering
Keywords:
New-age (Nano) Modified Emulsion (NME) stabilisation; identifying construction problems; preventing construction related problems; material related problems; constructability using nanotechnology applications; nano-silane stabilisation of granular materials; construction quality control problems; construction equipment problems; practical implementation of nano-silane stabilisation.
Online: 11 January 2022 (10:37:34 CET)
ARTICLE
|
doi:10.20944/preprints202108.0359.v2
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
1, 2, 4-Triazine; Lanosterol 14a-demethylase (CYP51); Drug Resistance; Molecular Docking; Molecular Dynamic Simulation.
Online: 17 August 2021 (12:27:02 CEST)
ARTICLE
|
doi:10.20944/preprints201807.0258.v1
Subject:
Engineering,
Electrical And Electronic Engineering
Keywords:
compressive sensing; orthogonal matching pursuit; hybrid optical cryptography; symmetric cryptography; asymmetric cryptography; Fourier related transforms; double random phase/amplitude optical key encryption; data compression; sensor reduction
Online: 16 July 2018 (07:36:09 CEST)
REVIEW
|
doi:10.20944/preprints202108.0447.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Interferons; IFNα; IFNß; IFNγ; antiviral; antiproliferative; immunomodulator; PEGylation; formulation; encapsulate IFNs; drug delivery system; liposomes; polymeric micelles; microparticles; nanoparticles
Online: 23 August 2021 (13:51:44 CEST)
ARTICLE
|
doi:10.20944/preprints202209.0417.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
Recreational substance abuse; drug abuse; marijuana; amphetamine; acute ischemic stroke; risk factors; young adult; NIS; Stroke; Sudden Cardiac Death
Online: 27 September 2022 (09:41:00 CEST)
ARTICLE
|
doi:10.20944/preprints202004.0198.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
mathematical modelling; peristalsis; smoothed particle hydrodynamics (SPH); fluid dynamics; large intestine; colonl proximal colon; fluid-structure interactions; drug delivery
Online: 12 April 2020 (15:57:17 CEST)
ARTICLE
|
doi:10.20944/preprints202006.0165.v2
Subject:
Biology And Life Sciences,
Virology
Keywords:
Conserved signature indels (CSIs) specific for SARS and SARS-CoV-2-related viruses. Molecular markers distinguishing different clades of Sarbecovirus, Evolutionary relationships between SARS and SARS-CoV-2-related viruses, Origin of SARS-CoV-2 and Pangolin CoV_MP789 viruses, Novel sequence and structural features of spike and nucleocapsid proteins. Genetic recombination.
Online: 26 August 2020 (10:17:16 CEST)
REVIEW
|
doi:10.20944/preprints202406.0054.v1
Subject:
Medicine And Pharmacology,
Dermatology
Keywords:
melanoma; cancer vaccine; mRNA vaccine; renin-angiotensin system; drug repurposing; immunotherapy; embryonic stem cells; cancer stem cells
Online: 3 June 2024 (09:54:04 CEST)
REVIEW
|
doi:10.20944/preprints201812.0170.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
bacterial nanocellulose; nanofibrillated nanocellulose; animal nanocellulose; algal nanocellulose; tissue engineering; tissue repair; wound dressing; cell delivery; drug delivery; antimicrobial properties
Online: 14 December 2018 (06:44:53 CET)
ARTICLE
Subject:
Public Health And Healthcare,
Public, Environmental And Occupational Health
Keywords:
Urban Heat Island; Heat-Related Health Risk (HRHR); Urban Landscape Metrics (ULM); Local Indicators of Spatial Autocorrelation (LISA); Spatial Error (SE) Regression; NCT-Delhi.
Online: 2 November 2020 (13:53:03 CET)
ARTICLE
|
doi:10.20944/preprints201811.0574.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
activity cliff; activity landscape plotter; epigenetics; docking; drug discovery; D-tools; molecular dynamics; Epi-polypharmacology; SmART; structure-activity relationships
Online: 26 November 2018 (07:14:05 CET)
ARTICLE
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
COVID-19; SARS-CoV-2; in silico drug discovery; gene expression profile; tensor decomposition; feature extraction
Online: 8 December 2020 (10:17:05 CET)
ARTICLE
|
doi:10.20944/preprints201812.0018.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
colorectal cancer; differentially expressed genes; biomarkers; protein-protein interaction; reporter biomolecules; candidate drugs; systems biology; drug repositioning
Online: 29 December 2018 (07:05:05 CET)
ARTICLE
|
doi:10.20944/preprints202408.1410.v1
Subject:
Public Health And Healthcare,
Public, Environmental And Occupational Health
Keywords:
Heat stress; Construction workers; Heat stress prevention program; Heat-related conditions; Worker safety; Well-being; Facilitators; Barriers. In this study, the terms ‘worker’ and ‘employee’ are used interchangeably.
Online: 20 August 2024 (09:05:55 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Covid-19; proteins; normal-modes; protein-drug interactions; chloroquine; ivermectin; remdesivir; sofosbuvir; boceprevir; α-difluoromethylornithine (DMFO)
Online: 11 August 2020 (04:09:43 CEST)
ARTICLE
|
doi:10.20944/preprints202405.1908.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Breast cancer; Target Identification; Protein-Protein Interaction; Network Pharmacology; Drug Discovery; KEEG; Enrichment analysis; Text Mining; Cytoscape
Online: 29 May 2024 (08:33:40 CEST)
REVIEW
|
doi:10.20944/preprints202401.1524.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
age-related macular degeneration; AMD; vascular endothelial growth factor; VEGF; anti-VEGF therapy; gene therapy; clinical trials; gene editing
Online: 22 January 2024 (10:11:17 CET)
ARTICLE
|
doi:10.20944/preprints202312.1632.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Transfusion-Dependent Thalassemia; Health-Related Quality of Life; Patient Reported Outcomes; disease-specific TranQol questionnaire; Healthcare policy; Thalassemia Unfastructure
Online: 21 December 2023 (13:41:48 CET)
ARTICLE
|
doi:10.20944/preprints202211.0392.v2
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Age-related Macular Degeneration; Artificial Intelligence; Machine Learning; Optical Coherence Tomography; Fundus Autofluorescence; regular fundus photography; Ultra-Widefield Fundus
Online: 8 May 2023 (14:25:29 CEST)
ARTICLE
|
doi:10.20944/preprints202304.1063.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
empagliflozin; vascular calcification; AMP-activated protein kinase; nuclear factor erythroid-2-related factor; heme oxygenase 1; chronic kidney disease
Online: 27 April 2023 (09:35:25 CEST)
CASE REPORT
|
doi:10.20944/preprints202011.0710.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
22q13.3 duplication; Auditory steady state response, ASSR; SHANK3; biomarker; auditory event-related potential, ERP; autism spectrum disorders; intellectual disabilities
Online: 30 November 2020 (08:33:26 CET)
ARTICLE
|
doi:10.20944/preprints202004.0171.v2
Subject:
Biology And Life Sciences,
Virology
Keywords:
protein functional domains; short linear motifs; coronaviruses; COVID-19; severe acute respiratory syndrome-related coronavirus; 2019-nCoV; virus outbreak
Online: 16 May 2020 (18:54:17 CEST)
ARTICLE
|
doi:10.20944/preprints202109.0052.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
RNAi; drug delivery; siRNA delivery; DsiRNA delivery; RNAi delivery; Chol-DsiRNA polymer micelles; Chol-siRNA polymer micelles
Online: 3 September 2021 (08:56:48 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1334.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
victimizing and perpetrating violence; interpersonal and intimate violence; harmful alcohol and drug use; mental health symptoms; paths of violence; gender
Online: 18 May 2023 (10:46:13 CEST)
ARTICLE
|
doi:10.20944/preprints202408.1941.v1
Subject:
Computer Science And Mathematics,
Mathematical And Computational Biology
Keywords:
Drug Response Prediction; Graph Neural Network; Graph Attention Networks; Heterogeneous Graph; Interpretability
Online: 27 August 2024 (12:44:15 CEST)
ARTICLE
|
doi:10.20944/preprints202407.1667.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
active targeting; CRT peptide; drug delivery; cancer; nanoemulsion
Online: 22 July 2024 (07:50:13 CEST)
ARTICLE
|
doi:10.20944/preprints202406.1032.v1
Subject:
Medicine And Pharmacology,
Endocrinology And Metabolism
Keywords:
Semaglutide Analogues; GLP-1 Receptor Agonists; Binding Affinity Optimization; Computational Drug Design;
Online: 17 June 2024 (09:12:54 CEST)
REVIEW
|
doi:10.20944/preprints202312.2253.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Ganoderma lucidum; Nanotechnology; Nanoparticles; Triterpenoids; Polysaccharides; Bioactive compounds; Drug delivery; Cancer therapy
Online: 29 December 2023 (11:31:12 CET)
ARTICLE
|
doi:10.20944/preprints202310.0396.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Pyrimidine; Homology Modelling; Pharmacophore Mapping; 3D-QSAR; Molecular Docking; ADMET; Drug Design
Online: 9 October 2023 (09:36:05 CEST)
ARTICLE
|
doi:10.20944/preprints202307.1577.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
deep learning, transformer, drug use detection, exploratory data analysis, natural language processing.
Online: 24 July 2023 (10:57:47 CEST)
REVIEW
|
doi:10.20944/preprints202306.0220.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
hydrogel-forming microneedles; transdermal drug delivery; controlled release; permeation pathway; environmental response
Online: 2 June 2023 (15:57:01 CEST)
REVIEW
|
doi:10.20944/preprints202305.1084.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
antibody-drug conjugate; lysosome; cathepsin; legumain; self-immolation; payload release; peptidomimetic; linker
Online: 16 May 2023 (04:51:34 CEST)
REVIEW
|
doi:10.20944/preprints202212.0207.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Blood-Brain Barrier; Brain Drug Delivery; Carbon Nanomaterials; Cerebral Gliomas; Glioblastoma; Nanoparticles.
Online: 12 December 2022 (14:56:45 CET)
ARTICLE
|
doi:10.20944/preprints202211.0296.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
antimicrobial resistance; broad-spectrum antibiotics; antibacterial drug discovery; gram-negative bacteria; pyrrolobenzodiazepines
Online: 16 November 2022 (04:20:55 CET)
REVIEW
|
doi:10.20944/preprints202211.0062.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
membrane transporter; SLC; solute carrier; drug design; pharmacokinetics; prodrug; nanoparticle; bile acids
Online: 3 November 2022 (01:09:54 CET)
ARTICLE
|
doi:10.20944/preprints202210.0141.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
AtbFinder; antibiotic susceptibility testing; cystic fibrosis; Pseudomonas aeruginosa; multi-drug re-sistant
Online: 11 October 2022 (04:56:32 CEST)
REVIEW
|
doi:10.20944/preprints202104.0652.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
Enzymatic reaction; crosslinking; Hydrogel; Biomedical application; Tissue engineering; Wound healing; Drug delivery
Online: 26 April 2021 (10:52:24 CEST)
ARTICLE
|
doi:10.20944/preprints202103.0621.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Auger electron; cisplatin; 191Pt; 189Pt; radio-drug; DNA double-strand break; γH2AX
Online: 25 March 2021 (14:30:14 CET)
CASE REPORT
|
doi:10.20944/preprints202103.0054.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
DRESS syndrome, Eosinophilia, Adverse drug reaction, HHV-6 reactivation, Bactrim adverse reaction
Online: 2 March 2021 (09:26:48 CET)
REVIEW
|
doi:10.20944/preprints202102.0449.v1
Subject:
Chemistry And Materials Science,
Materials Science And Technology
Keywords:
multifunctional; hydrogel nanocomposties; tissue engineering; drug delivery; wound healing; bioprinting; biowearable devices
Online: 22 February 2021 (08:48:20 CET)
ARTICLE
|
doi:10.20944/preprints202012.0513.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
apoferritin nanocarriers; controlled drug delivery; idarubicin; ferritin receptor targeting; folate receptor targeting
Online: 21 December 2020 (11:28:08 CET)
COMMUNICATION
|
doi:10.20944/preprints202011.0441.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Sars-Cov-2; Proteomic,; Ghost proteome,; Alternative proteins,; AltOrf.; interactomic; drug repurposing
Online: 16 November 2020 (17:50:19 CET)
ARTICLE
|
doi:10.20944/preprints202004.0524.v2
Subject:
Biology And Life Sciences,
Virology
Keywords:
unsupervised learning; tensor decomposition; feature selection; COVID-19; drug discovery; gene expression
Online: 3 June 2020 (05:29:09 CEST)
ARTICLE
|
doi:10.20944/preprints202002.0178.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
DILIrank; DILI; drug hepatotoxicity; QSAR; nested cross-validation; virtual screening; in silico
Online: 14 February 2020 (02:24:04 CET)
REVIEW
|
doi:10.20944/preprints201906.0002.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
patient-derived xenograft; immunocompromised mice; precision medicine; drug screening; cancer; cell line
Online: 3 June 2019 (04:47:14 CEST)
ARTICLE
|
doi:10.20944/preprints201810.0381.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Biginelli reaction; dihydropyrimidin-2-thiones; synthesis, virtual screening, drug design; LaSOM 282
Online: 17 October 2018 (09:34:06 CEST)
ARTICLE
|
doi:10.20944/preprints201712.0024.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
HIV-1; quasispecies; minority resistance mutations; HAART; drug resistance; undetectable viral load
Online: 4 December 2017 (09:34:16 CET)
COMMUNICATION
|
doi:10.20944/preprints202309.1794.v1
Subject:
Medicine And Pharmacology,
Complementary And Alternative Medicine
Keywords:
SARS; Covid-19; HIV; MRSA; Biophotonics; Energy Dynamics; Electromagnetic therapy; irradiation; immunomodulation; infectious illnesses; drug resistance; therapeutic efficacy
Online: 27 September 2023 (04:45:42 CEST)
REVIEW
|
doi:10.20944/preprints201812.0273.v3
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
mutations; disease-causing mutations; polymorphism; folding free energy change; binding free energy change; drug discovery; in silico screening
Online: 28 January 2019 (11:39:23 CET)
ARTICLE
|
doi:10.20944/preprints202003.0440.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
COVID-19; SARS-CoV-2; 2019-nCoV; novel corona virus; drug repurposing; chloroquine; high-risk group; asymptomatic
Online: 30 March 2020 (07:24:16 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0258.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Parkinson-like events; Japanese Adverse Drug Event Report database; spontaneous reporting system; volcano plot; hierarchical clustering; principal component analysis
Online: 5 June 2024 (08:25:00 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0480.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
camptothecin; drug distribution; drug-membrane interaction; biophysical profiling; biomimetic models; partition coefficient; ADMET/PK prediction; small and wide-angle X-ray diffraction; fluorescence spectroscopy; human serum albumin (HSA)
Online: 20 May 2021 (10:52:33 CEST)
ARTICLE
|
doi:10.20944/preprints202111.0460.v1
Subject:
Medicine And Pharmacology,
Dietetics And Nutrition
Keywords:
Maintenance hemodialysis (MHD) patient; Low-phosphate meal; CKD-MBD (chronic kidney disease-related mineral and bone disorder); Proinflammatory cytokine; TNF-α (tumor necrosis factor-alpha)
Online: 24 November 2021 (15:27:03 CET)
ARTICLE
|
doi:10.20944/preprints202401.1988.v1
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
severe traumatic brain injury; regulatory T cell; forkhead box protein 3; T helper 17; retinoic acid receptor-related orphan receptor gamma t; gut microbiome; probiotic
Online: 29 January 2024 (08:51:54 CET)
REVIEW
|
doi:10.20944/preprints202012.0044.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Integrins; Tumor Microenvironment; Drug Resistance; Migration; Metastasis; Solid Tumors; The Cancer Genome Atlas; Gene Expression; Computational Biology; Therapeutic Targeting
Online: 1 December 2020 (18:26:11 CET)
ARTICLE
|
doi:10.20944/preprints202401.1163.v1
Subject:
Medicine And Pharmacology,
Psychiatry And Mental Health
Keywords:
opioids; opium smoking; substance use disorder; behavioral addiction; drug use disorder; sway back posture; musculoskeletal disorders; Nordic; Iran
Online: 16 January 2024 (09:42:41 CET)
ARTICLE
|
doi:10.20944/preprints201706.0132.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
arylamine N-acetyltransferases; cancer; tuberculosis; drug discovery; traditional Chinese medicine; virtual screening; molecular dynamics simulation; MM-PBSA
Online: 30 June 2017 (11:36:22 CEST)
REVIEW
|
doi:10.20944/preprints202303.0464.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Therapeutic proteins; Recombinant proteins; Repurposing; Reinventing, Drug-antibody combinations, AI/ML, Efficacy improvement, Immunogenicity; Artificial Intelligence; mRNA; High throughput analysis
Online: 27 March 2023 (14:02:03 CEST)
ARTICLE
|
doi:10.20944/preprints202101.0478.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
ocular drug delivery system; topical liposomes; posterior segment of the eye; safety and toler-ability; biologic activity; diabetic macular edema
Online: 25 January 2021 (10:48:51 CET)
REVIEW
|
doi:10.20944/preprints202312.1480.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
Nano-drugs; Nanoparticle; Delivery System; Vaccine; Liposome; Exosome; Stealth Effect; SLN; Inclusion and Dispersion Systems; Solid State Reactive Mixing; Nanosome; Drug Carrier
Online: 20 December 2023 (10:54:31 CET)
REVIEW
|
doi:10.20944/preprints202010.0179.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Non Michaelis-Menten Kinetics; High-throughput screening; allostery; cooperativity; processive kinetics; distributive kinetics; single-molecule; auto-catalytic; drug discovery
Online: 8 October 2020 (13:34:16 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0925.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
age-related amyloid, Congo red staining, constipation, epidermal growth factor-containing fibulin-like extracellular matrix protein 1, lower gastrointestinal tract
Online: 13 June 2024 (14:53:40 CEST)
ARTICLE
|
doi:10.20944/preprints202401.2015.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
age-related macular degeneration; pachychoroid neovasculopathy; photodynamic therapy; anti-vascular endothelial growth factor therapy; ultra-wide-field optical coherent tomography
Online: 29 January 2024 (13:01:33 CET)
ARTICLE
|
doi:10.20944/preprints202102.0296.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
End-Stage Renal Disease, Chronic Kidney Disease, Wnt-Pathway, R-Spondin 1, β-Catenin, Dickkopf-Related Protein 1, and Sclerostin.
Online: 12 February 2021 (10:08:22 CET)
ARTICLE
Subject:
Social Sciences,
Psychology
Keywords:
COVID-19; lockdown; digital literacy; academic meetings; private Facebook groups; Zoom; 4Cs; health-related group; landscape of truth; narrative research
Online: 3 August 2020 (08:38:41 CEST)
REVIEW
|
doi:10.20944/preprints202401.0233.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Gold nanoparticle; nanomedicine; glioblastoma multiforme; blood-brain barrier; brain tumor treatment; targeted drug delivery; radiation treatment; boron neutron capture therapy
Online: 3 January 2024 (10:03:43 CET)