ARTICLE
|
doi:10.20944/preprints202405.0110.v1
Subject:
Public Health And Healthcare,
Other
Keywords:
Peripheral artery disease (PAD); modified cumulative risk (MCR) score; CHA2DS2-VASc; Major adverse cardiovascular events (MACE); Major adverse limb events (MALE); percutaneous coronary intervention (PCI)
Online: 2 May 2024 (09:41:19 CEST)
ARTICLE
|
doi:10.20944/preprints202404.0837.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
rare disease; genomics; explainable; machine learning; pathogenic; variant consequence; classification; prioritization
Online: 12 April 2024 (09:59:40 CEST)
ARTICLE
|
doi:10.20944/preprints202303.0323.v1
Subject:
Engineering,
Bioengineering
Keywords:
Multiscale Sample Entropy; Refine Composite Multiscale Entropy; Cerebellar Ataxia; Parkinson’s disease; Trunk acceleration time series; Complexity index; Gait variability; Gait complexity; Gait pattern; Movement disorders
Online: 17 March 2023 (10:11:42 CET)
ARTICLE
|
doi:10.20944/preprints202301.0500.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Alzheimer’s Disease (AD) mitochondria; endoplasmic reticulum (ER); serial block-face scanning electron microscopy (SBFSEM); three-dimensional electron microscopy (3D EM); small molecule mitochondria targeted therapeutics
Online: 27 January 2023 (10:08:59 CET)
ARTICLE
|
doi:10.20944/preprints202207.0358.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Foot-and-mouth disease virus; safe sample transport; single-stranded positive-sense RNA; TRIzol extraction; naked RNA; infectivity; RNA transfection; lipofectamine; self-transfection; BHK cells
Online: 25 July 2022 (08:14:51 CEST)
ARTICLE
|
doi:10.20944/preprints202207.0339.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
Infectious disease testing; public health preparedness; point-of-care testing (POCT); molecular diagnostics; therapeutic turnaround time (TTAT); acute medical challenges; geographic information systems; antimicrobial stewardship
Online: 22 July 2022 (13:13:53 CEST)
ARTICLE
|
doi:10.20944/preprints202202.0055.v2
Subject:
Social Sciences,
Psychology
Keywords:
Coronavirus disease 2019/COVID-19; Internet Gaming Disorder Scale9—Short form (IGDS9-SF); university students; factorial structure/psychometric properties/structural validity/validation; cultur*/collectivisti*/individualis*; invariance; gender; game type
Online: 21 March 2022 (11:04:57 CET)
ARTICLE
|
doi:10.20944/preprints202111.0460.v1
Subject:
Medicine And Pharmacology,
Dietetics And Nutrition
Keywords:
Maintenance hemodialysis (MHD) patient; Low-phosphate meal; CKD-MBD (chronic kidney disease-related mineral and bone disorder); Proinflammatory cytokine; TNF-α (tumor necrosis factor-alpha)
Online: 24 November 2021 (15:27:03 CET)
CONCEPT PAPER
|
doi:10.20944/preprints202106.0486.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
high altitude, chronic hypobaric hypoxia, physiologic adaptation, travel to high altitude cities, high altitude physiology, pulmonary hypertension, lung disease, hemoglobin, tolerance to hypoxia, oxygen content.
Online: 18 June 2021 (15:22:04 CEST)
ARTICLE
|
doi:10.20944/preprints201808.0463.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Factor Xa ( F-Xa), Cardiovascular diseases (CD), Coronary heart disease (CHD), Tissue plasminogen activator (t-PA), Urokinase (UK), Streptokinase (SK), N,N-Dimethyl formamide (DMF)
Online: 27 August 2018 (14:54:10 CEST)
ARTICLE
|
doi:10.20944/preprints201804.0278.v1
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
monocyte chemoattractant protein-1; MCP-1; C-C motif chemokine ligand 2; CCL2; childhood asthma; bronchial asthma; severe asthma; cystic fibrosis; chronic obstructive pulmonary disease
Online: 23 April 2018 (09:00:00 CEST)
ARTICLE
|
doi:10.20944/preprints201711.0193.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
computational intelligence; quantum hybrid intelligent systems; quantum machine learning; medical image processing; disease diagnosis; Fuzzy k-NN; Quantum-behaved PSO; cervical smear images; cancer detection
Online: 30 November 2017 (07:21:00 CET)
ARTICLE
|
doi:10.20944/preprints202408.0230.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Receptor Binding Domain (RBD); Memory B-cell (MBC); Antibody-secreting cell (ASC); Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2); Coronavirus Disease-2019 (COVID-19)
Online: 6 August 2024 (06:05:27 CEST)
ARTICLE
|
doi:10.20944/preprints202401.1981.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Adrenergic signaling in cardiomyocytes; cardiac muscle contraction; Chagas disease; diabetic car-diomyopathy; dilated cardiomyopathy; glycerolipid metabolism; glycolisis/glucogenesis; hyper-trophic cardiomyopathy; purine metabolism; steroid hormone biosynthesis
Online: 29 January 2024 (08:48:50 CET)
ARTICLE
|
doi:10.20944/preprints202308.1752.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Intracerebroventricular, ICV; mTOR, mTOR-I, rapalog; Tuberous Sclerosis, TSC; Multiple Sclerosis, MS; Experimental Autoimmune Encephalitis, EAE; Alzheimer’s Disease, AD; Thermostable Micelles, Micellar Liquid Formulation; Ommaya device
Online: 24 August 2023 (12:53:26 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1047.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
Age-related Macular Degeneration (AMD); Cornea; docosahexaenoic acid (DHA); drug delivery; non-invasive ocular delivery platform (NIODP); ocular disease; omega-3; retina; retinal delivery; retinal dis
Online: 14 August 2023 (15:18:22 CEST)
REVIEW
|
doi:10.20944/preprints202304.0366.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
Dry eye disease (DED); Diquafosol; Cyclosporine; Supplement; Contact lens; Human umbilical cord serum; Intense pulsed light; Lid debris debridement; Vectored thermal pulsation; Intraductal meibomian gland probing
Online: 14 April 2023 (10:36:02 CEST)
ARTICLE
|
doi:10.20944/preprints202302.0198.v1
Subject:
Engineering,
Electrical And Electronic Engineering
Keywords:
Infected lung segmentation; Quantification of lung disease severity; Comparison be-tween manual and automated image segmentation; Deep Neural Network; COVID-19 detections; COVID-19 severity assessment
Online: 13 February 2023 (06:33:31 CET)
ARTICLE
|
doi:10.20944/preprints202112.0041.v1
Subject:
Medicine And Pharmacology,
Endocrinology And Metabolism
Keywords:
Vascular inflammation; Peripheral arterial disease (PAD); Chronic limb-threatening ischemia (CLTI); GHAS trial; TNF-α; hs-CRP; Neutrophil-to-lymphocyte ratio (NLR); NOX4; eNOS; VEGF-A.
Online: 3 December 2021 (09:44:42 CET)
ARTICLE
|
doi:10.20944/preprints202007.0340.v1
Subject:
Computer Science And Mathematics,
Applied Mathematics
Keywords:
energy landscapes; ultarmetric spaces; p-adic numbers; ultarmetric diffusion equation; social barriers; linear growing barriers; covid-19; epidemic; disease spread; herd immunity; hierarchy of social clusters
Online: 16 July 2020 (04:14:42 CEST)
ARTICLE
|
doi:10.20944/preprints201809.0272.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Keywords: 1; genome 2; epigenetics 3; neurodevelopmental disorders; 4; chromosome anomalies; 5; retrotransposon; 6; chromosome rearrangement; 7; neurologic disease; 8; birth defects; 9; development 10; infection
Online: 15 September 2018 (18:07:03 CEST)
REVIEW
|
doi:10.20944/preprints202408.0858.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
Dietary fats
Inflammation
disease management
Psoriasis
Psoriatic arthritis
QoL (quality of Life)
Inflammation
disease management
Psoriasis
Psoriatic arthritis
QoL (quality of Life)
Online: 15 August 2024 (09:12:17 CEST)
ARTICLE
|
doi:10.20944/preprints202407.0723.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Maresin-like; Alzheimer's Disease; neuroinflammation; neuropathogenesis; amyloid-β (Aβ ); cholinergic neuron; cleaved-caspase-3; M1 or M2 microglia; A1 or A2 astrocytes; N1 or N2 neutrophil
Online: 9 July 2024 (12:24:29 CEST)
ARTICLE
|
doi:10.20944/preprints202402.1708.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Mucopolysaccharidosis type II; Disease Modelling; in vitro models; induced Pluripotent Stem Cells (iPSCs); Dental Pulp Stem Cells (DPSCs); SHED: Stem cells from Human Exfoliated Deciduous teeth (SHEDs)
Online: 29 February 2024 (13:03:37 CET)
ARTICLE
|
doi:10.20944/preprints202305.0700.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
allogeneic hematopoietic stem cell transplantation; autoimmune limbic encephalitis; cyclo-phosphamide; regulatory T cells; CD25; Foxp3; IL-6; fever; acute graft-versus-host disease; cyto-kine-release syndrome
Online: 10 May 2023 (07:46:24 CEST)
REVIEW
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
glucose; glycogen; gluconeogenesis; early life adversity; acute stress; chronic stress; psychosocial stress; hypothalamus-pituitary-adrenal axis; ageing; immuno-senescence; inflamm-ageing; Developmental origins of health and disease
Online: 23 March 2021 (09:04:41 CET)
ARTICLE
|
doi:10.20944/preprints202005.0001.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
CRISPR-Cas9; high-content screening (HCS); fluorescent-activated cell sorting (FACS); Parkinson's disease (PD); patient-derived iPS; single-cell clones; isogenic cell lines; SNCA; alpha-synuclein; A30P
Online: 2 May 2020 (11:20:20 CEST)
REVIEW
|
doi:10.20944/preprints202001.0042.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
computed tomography (CT); magnetic resonance imaging (MRI); leukoaraiosis (LA); white matter hyperintensities (WMH); small vessels disease (SVD); periventricular white matter hyperintensities (PWMH); deep white matter hyperintensities (DWMH)
Online: 5 January 2020 (16:11:25 CET)
ARTICLE
|
doi:10.20944/preprints202405.1741.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Alzheimer’ s disease; vascular complications; monoclonal antibody therapy; Aducanumab; Lecanemab; epoxide of polyunsaturated fatty acid; soluble epoxide hydrolase inhibitor EC5026; EP4 inhibitor; monocyte/macrophage; amyloid-beta degradation
Online: 27 May 2024 (13:00:54 CEST)
REVIEW
|
doi:10.20944/preprints202401.1684.v1
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
False Liver Metastasis; neoadjuvant chemoradiotherapy (nCRT); F-18-fluorodeoxyglucose (18F-FDG); positron emission tomography computed tomography (PET-CT); radiation-induced liver injury (RILI); radiation-induced liver disease (RILD)
Online: 23 January 2024 (09:23:05 CET)
REVIEW
|
doi:10.20944/preprints202401.0237.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
congenital heart disease; first heart field; second heart field; whole exome sequencing; whole genome sequencing; loss-of-function variant; copy number variants; gene variants; deletion; de novo mutations
Online: 3 January 2024 (11:57:54 CET)
REVIEW
|
doi:10.20944/preprints202010.0510.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
disease-associated mutation; IDR; intrinsically disordered region; LLPS; phase separation; PTM; Ahr; AhRR; SIM1; SIM2; Hif-2α; NPAS4; ARNT2; BMAL1; disorder prediction; LLPS prediction; cancer; HuVarBase; catGranule prediction
Online: 26 October 2020 (10:30:47 CET)
REVIEW
|
doi:10.20944/preprints202306.1113.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
Inflammatory bowel disease; Colitis-associated colorectal cancer; exogenous frees hemoglobin alpha chain; Fenton reaction; DNA damage; haptoglobin; deferoxamine; flavonoids; hydrogen peroxide; hygiene; iron; nanomedicine; oxidative stress; polyphenol; pharmaceutical therapy
Online: 16 June 2023 (07:11:38 CEST)
ARTICLE
|
doi:10.20944/preprints202211.0028.v1
Subject:
Medicine And Pharmacology,
Dietetics And Nutrition
Keywords:
Anthropometric measurements; fatty liver disease; nutritional intervention; imaging techniques; long-term follow-up; neck-to-height ratio; non-invasive diagnostic methods; neck-to-weight ratio; FLIO study; steatosis markers.
Online: 1 November 2022 (10:04:57 CET)
ARTICLE
|
doi:10.20944/preprints202404.0794.v1
Subject:
Biology And Life Sciences,
Agricultural Science And Agronomy
Keywords:
electronic nose; headspace GC-MS analysis; Linear Discriminant Analysis (LDA); Principal Component Analysis (PCA); Volatile Organic Compounds (VOC); Chemometric Data Analysis (CDA); Panama Disease (TR4); Mango Twig Tip Dieback (MTTD)
Online: 11 April 2024 (11:13:59 CEST)
ARTICLE
|
doi:10.20944/preprints202311.0643.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Parkinson’s disease; axial motor symptoms; postural instability & gait difficulties; functional limits of stability; non-motor sensory symptoms; sensorimotor integration; somatosensory system; plantar cutaneous vibration perception thresholds; deep brain stimulation; subthalamic nucleus
Online: 10 November 2023 (01:49:33 CET)
HYPOTHESIS
|
doi:10.20944/preprints202109.0372.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Endometriosis; microchimerism; maternal microchimerism; reproduction; gynaecology; etiology; auto-immune; immune response; hormonal; vascular; genetic; hereditary; male; fetal; fetus; stem cells; pregnancy; Műllerianosis; embryology; ROS; apoptosis; disease; endometrium; basalis; menstruation; post-menopausal; neurogenesis
Online: 22 September 2021 (10:27:52 CEST)
REVIEW
|
doi:10.20944/preprints202303.0126.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
sarcoidosis; Mycobacterium avium ss. paratuberculosis; MAP; non-caseating granuloma; caseating granuloma; Blau syndrome; early onset sarcoidosis; Crohn’s disease; cell wall deficient (CWD); L-form; Mycobacterium tuberculosis; acid-fast bacilli; SLC11a1 (NRAMP1); NOD2 (CARD15)
Online: 7 March 2023 (03:46:55 CET)
REVIEW
|
doi:10.20944/preprints202111.0253.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
Cell therapy; chronic limb-threating ischemia; peripheral artery disease; diabetes; atherosclerosis obliterans; thromboangiitis obliterans; personalized medicine; artificial intelligence; machine learning; genome-wide association studies; transcriptome-wide association studies; clonal hematopoiesis of indeterminate potential.
Online: 15 November 2021 (11:18:43 CET)
ARTICLE
|
doi:10.20944/preprints202308.1497.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
Coronavirus disease-2019 (COVID-19); Emergency Use Authorization (EUA); false negative (FN); false omission rate (RFO); point-of-care testing (POCT); prevalence boundary (PB); rapid antigen test (RAgT); repeated testing; sensitivity and specificity; tier
Online: 22 August 2023 (07:25:00 CEST)
ARTICLE
|
doi:10.20944/preprints201907.0347.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
autograft; embryonic stem cells (ESC); growth factor (GF); hereditary retinal disease; induced pluripotent stem cells (iPSCs); Limoli retinal restoration technique (LRRT); mesenchymal stem cell (MSC); retinitis pigmentosa; spectral domain-optical coherence tomography (SD-OCT)
Online: 31 July 2019 (04:45:51 CEST)
REVIEW
|
doi:10.20944/preprints202402.0963.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
POMS; Pediatric Onset Multiple Sclerosis; Disease-modifying therapies; DMT; Pediatric MS; Interferons; Finglolimod; Teriflunomide; Cyclophosphamide; Rituximab; Ocrelizumab; Daclizumab; Alemtuzumab; Natalizumab; Ofatumumab; Siponimod; Vitamin D; TCR vaccine; Stem cell therapy; Glatiramer acetate; Azathioprine; Dimethyl fumarate; Mitoxantrone
Online: 19 February 2024 (14:52:05 CET)
ARTICLE
|
doi:10.20944/preprints202401.1971.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Aedes aegypti; Aedes albopictus; Anopheles culicifacies; Anopheles stephensi; Borreliosis; Dengue; Climate change; COVID-19; Lyme disease; Malaria; Salinity adaptation in mosquito vectors; Serodiagnosis; Tick-borne relapsing fever; Vaccines
Online: 29 January 2024 (04:35:25 CET)
ARTICLE
|
doi:10.20944/preprints202301.0448.v1
Subject:
Social Sciences,
Psychology
Keywords:
Impact of Event Scale-Revised (IES-R)/post-traumatic stress disorder (PTSD); cutoff point/cutoff score; psychiatric patients/the general public/healthy adults; psychometric evaluation/criterion validity; Coronavirus Disease-19/COVID-19; Arabic version/Arab/Saudi Arabia
Online: 25 January 2023 (05:02:13 CET)
REVIEW
|
doi:10.20944/preprints202402.1353.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Infectious disease agents in aquaculture; Fish Vaccine, Fish immunology; Bacterial, viral, and parasitic diseases in aquaculture; Recombinant live attenuated, subunit, DNA, and RNA vaccines for fish; Sustainability of aquaculture; The innate and adaptive immune system of fish; Fish immunological mechanisms
Online: 24 February 2024 (08:58:46 CET)
REVIEW
|
doi:10.20944/preprints202303.0500.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
Oxidative stress and cell death; Reactive oxygen species; ROS; ROS cell death; autophagy; role of antioxidants; eye disease; cornea; lens; epithelium; retinal ganglion cells; retinal pigment epithelium; macular degeneration; antioxidants in the macula; oxidative stress prevention with antioxidants; lifestyle changes; digital eye strain; glaucoma; cataracts; dry eye disease; computer vision syndrome; digital eye strain; diabetic retinopathy; Vitamin A; Vitamin C; copper; glutathione; zinc; selenium; magnesium; blue light damage; UV light damage; blue light reactive oxygen species; autophagy; ferroptosis; ROS cell death; superoxide dismutase; optic nerve gliomas; food deserts; myopia; free radicals
Online: 29 March 2023 (03:33:55 CEST)
ARTICLE
|
doi:10.20944/preprints202109.0014.v1
Subject:
Social Sciences,
Psychology
Keywords:
Coronavirus disease 2019/COVID-19; Depression Anxiety Stress Scales-21/DASS-21; DASS-8; shortened version*; shorter version* of the DASS-21; psychiatric disorders; factorial structure/psychometric properties/structural validity/validation; measurement invariance/multigroup analysis; psychological distress; discriminant validity; item coverage; good predictive validity
Online: 1 September 2021 (12:15:27 CEST)
ARTICLE
|
doi:10.20944/preprints202211.0236.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
Acute exacerbation chronic obstructive pulmonary disease (AECOPD); platelet-to-lymphocyte ratio (PLR); neutrophil-to-lymphocyte ratio (NLR); monocyte-to-lymphocyte ratio (MLR); baso-phil-to-lymphocyte ratio (BLR); eosinophil-to-lymphocyte ratio (ELR); in-hospital mortality; nom-ogram; decision curve analysis (DCA); clinical impact curve (CIC)
Online: 14 November 2022 (04:42:59 CET)
REVIEW
|
doi:10.20944/preprints202402.0879.v1
Subject:
Medicine And Pharmacology,
Psychiatry And Mental Health
Keywords:
Alzheimer’ s disease;
Parkinson’ s disease;
aging decline;
mild cognitive impairment;
multiple sclerosis;
stroke;
psychiatric disorders;
depressive disorder;
bipolar disorder;
post-traumatic stress disorder;
anxiety disorder;
schizophrenia;
somatic symptom disorder;
autism spectrum disorder;
hyperactive attention deficit disorder;
learning disabilities;
acquired brain damage;
altered cognitive processes;
brain functional impairment;
neurocognitive disorders;
cognitive, behavioral, and functional disorders;
acquired trauma;
brain plasticity and connectivity;
non-invasive brain stimulation;
diagnosis and treatment;
functional evidence of altered cognition and connectivity
Parkinson’ s disease;
aging decline;
mild cognitive impairment;
multiple sclerosis;
stroke;
psychiatric disorders;
depressive disorder;
bipolar disorder;
post-traumatic stress disorder;
anxiety disorder;
schizophrenia;
somatic symptom disorder;
autism spectrum disorder;
hyperactive attention deficit disorder;
learning disabilities;
acquired brain damage;
altered cognitive processes;
brain functional impairment;
neurocognitive disorders;
cognitive, behavioral, and functional disorders;
acquired trauma;
brain plasticity and connectivity;
non-invasive brain stimulation;
diagnosis and treatment;
functional evidence of altered cognition and connectivity
Online: 16 February 2024 (05:40:14 CET)