REVIEW
|
doi:10.20944/preprints202302.0006.v1
Subject:
Medicine And Pharmacology,
Dietetics And Nutrition
Keywords:
hormesis; polyphenols; clinical trials; antioxidants; reactive oxygen species; oxidative stress; plant-derived antioxidants; dietary antioxidants; nutritional hormesis; free radicals
Online: 1 February 2023 (03:03:40 CET)
ARTICLE
|
doi:10.20944/preprints202102.0001.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Giant cell arteritis; anterior ischemic optic neuropathy; clinical prediction rule; diagnostic algorithm; C-reactive protein; temporal compression sonography; ultrasound
Online: 1 February 2021 (08:44:33 CET)
REVIEW
|
doi:10.20944/preprints202101.0625.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Alzheimer’s disease; dementia, beta-amyloid; germ theory; drug development; clinical trials; herpes; spirochetes; Chlamydia pneumoniae; Porphyromonas gingivalis; toxoplasma; mycobacteria
Online: 29 January 2021 (13:57:18 CET)
REVIEW
|
doi:10.20944/preprints202012.0504.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
dysphagia; swallowing impairment; videofluorographic swallowing study; literature review; procedures; indications; normal and critical findings; interfering factors; complications; clinical significance
Online: 21 December 2020 (10:55:05 CET)
REVIEW
|
doi:10.20944/preprints202011.0156.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
Bacterial detection; Biosensors; Clinical pathogen; COVID-19; Electrospun nanofibers; Nano-biosensors; Point-of-care; SARS-CoV-2; Viral detection.
Online: 3 November 2020 (14:15:34 CET)
ARTICLE
|
doi:10.20944/preprints202009.0572.v1
Subject:
Medicine And Pharmacology,
Other
Keywords:
randomized controlled clinical trials; mathematical model; binary system; statistical analysis; epidemiological model; junk science; reductionist treatments; failure of medicine
Online: 24 September 2020 (08:13:15 CEST)
COMMUNICATION
|
doi:10.20944/preprints201912.0203.v1
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
mobile technology; patient engagement; mobile clinical trials; virtual trials; digital trials; hybrid trials; site engagement; site support; mobile devices
Online: 16 December 2019 (02:44:52 CET)
REVIEW
|
doi:10.20944/preprints202401.0362.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
leukemia; natural substances; telomerase; antioxidant; hematological malignancy; genomic instability; DNA damage; polyphenols; vitamins; in vitro; in vivo and clinical trials
Online: 4 January 2024 (07:38:26 CET)
ARTICLE
|
doi:10.20944/preprints202310.1435.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Alzheimer's Disease (AD); Convolutional Neural Networks (CNNs); Biomarkers of AD; Early clinical symptoms; Risk factors; Diagnosis of AD; Medical Images
Online: 23 October 2023 (10:29:48 CEST)
REVIEW
|
doi:10.20944/preprints202308.1673.v1
Subject:
Biology And Life Sciences,
Parasitology
Keywords:
Non-ulcerated cutaneous leishmaniasis; visceral leishmaniasis; biological, epidemiological, clinical-immunological, and molecular taxonomic analysis; Leishmania (Leishmania) poncei; Honduras; Central America
Online: 24 August 2023 (03:43:47 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0774.v1
Subject:
Biology And Life Sciences,
Parasitology
Keywords:
canine leishmaniasis; natural zoonotic infection; clinical and histopathologic features; cell communication by secreting extracellular vesicles; lipid profiles of cultured parasites.
Online: 9 August 2023 (10:50:56 CEST)
ARTICLE
|
doi:10.20944/preprints202301.0363.v1
Subject:
Medicine And Pharmacology,
Dentistry And Oral Surgery
Keywords:
Periodontal Disease; Electronic Dental Record; Longitudinal Data; Data Quality; Dental Infor-matics; Clinical Course of Periodontal Disease; Periodontal Cohort Generation
Online: 19 January 2023 (13:01:27 CET)
ARTICLE
|
doi:10.20944/preprints202206.0394.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
deep learning; DNN; machine learning; breast cancer; metastasis, metastatic breast cancer, distant recurrence of breast cancer metastasis; prediction; clinical; EHR
Online: 29 June 2022 (04:06:16 CEST)
ARTICLE
|
doi:10.20944/preprints202205.0202.v2
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
Clinical handover; Patient Handoff; Patient transfer; Referral and Consultation; Medical Records Systems; Computerized; Patient Safety; Risk Management; Attitude; Institutional Practice
Online: 31 May 2022 (07:14:42 CEST)
REVIEW
|
doi:10.20944/preprints201806.0137.v1
Subject:
Medicine And Pharmacology,
Other
Keywords:
opportunity; challenge; perspective; health data; disease prediction; clinical outcome prediction; healthcare process; data quality; quantity and quality analysis; artificial intelligence
Online: 8 June 2018 (13:22:08 CEST)
REVIEW
|
doi:10.3390/sci2030068
Subject:
Medicine And Pharmacology,
Tropical Medicine
Keywords:
COVID-19; pooling clinical trials; hyperinfection; steroids; treatment; targeted healthcare; population health management; cancer treatment; clinical research; clinical trials; developing vaccines; ranking and rating hospital quality; school closures; interventions for delirium; assessments of COVID-19 death inequities; regulatory safeguards; preventing child abuse and maltreatment; prevalence of health care worker burnout; nursing home ratings; challenging oncology practice; addressing racial; ethnic; social and economic divides; violence against sexual minority adolescents; primary tumors; metastasis; stages of cancer; reforming cancer clinical trials; supporting carers; protection and prevention; benign and malignant tumors; reforming cancer clinical trials; protection of healthcare personnel; comparing excess deaths in NYC; 1918 influenza pandemic; the possibility of full recovery from COVID-19; mental health impact of COVID-19 on young adults; ranking and rating nursing home quali
Online: 21 August 2020 (00:00:00 CEST)
REVIEW
|
doi:10.20944/preprints202402.1593.v1
Subject:
Medicine And Pharmacology,
Endocrinology And Metabolism
Keywords:
type 2 diabetes; therapeutic inertia; clinical guidelines; sodium-glucose cotransporter-2 inhibitors; glucagon-like peptide-1 receptor agonists; primary health care
Online: 28 February 2024 (10:53:42 CET)
REVIEW
|
doi:10.20944/preprints202402.1245.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Parkinson’ s disease; type 2 diabetes mellitus; GLP1-R agonists; GLP-1; exendin-4; liraglutide; lixisenatide; semaglutide; clinical trials; neurodegeneration
Online: 22 February 2024 (12:38:30 CET)
ARTICLE
|
doi:10.20944/preprints202312.1562.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
Automatic segmentation; anatomical structures; multi-label segmentation; clinical target volume delineation; lymph node level segmentation; expert guidelines; head and neck cancer.
Online: 20 December 2023 (12:45:16 CET)
ARTICLE
|
doi:10.20944/preprints202305.0513.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
deep learning; medical imaging; clinical decision support system; Teeth X-Rays; Images; CNN model; transfer learning; NASNetMobile feature extractor; classification model
Online: 8 May 2023 (10:25:36 CEST)
REVIEW
|
doi:10.20944/preprints202305.0472.v1
Subject:
Public Health And Healthcare,
Health Policy And Services
Keywords:
diagnostic molecular pathology; genetic testing; diagnostic services; technology assess- ment; biomedical; genetic services; financial support; clinical governance; health technology; healthcare innovation
Online: 8 May 2023 (08:36:59 CEST)
ARTICLE
|
doi:10.20944/preprints202303.0470.v1
Subject:
Medicine And Pharmacology,
Other
Keywords:
design; clinical decision support systems; intelligent systems; expert systems; Machine Learning; decision-making; medical algorithm; design science research.; obstructive sleep apnea
Online: 28 March 2023 (03:18:38 CEST)
ARTICLE
|
doi:10.20944/preprints202010.0392.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
antimicrobial stewardship; detection of bacteria in chronic wounds, chronic wounds, clinical decision support; diagnostic pathway; joint commission; fluorescence imaging; wound clinic
Online: 19 October 2020 (15:35:25 CEST)
ARTICLE
|
doi:10.20944/preprints202003.0297.v1
Subject:
Computer Science And Mathematics,
Information Systems
Keywords:
Data Mining; Alzheimer’s Dementia; Composite Hybrid Feature Selection; Machine learning; Stack Hybrid Classification; AI Techniques; Classification; AD Diagnose; Clinical AD Dataset
Online: 19 March 2020 (10:52:31 CET)
REVIEW
|
doi:10.20944/preprints202405.1755.v1
Subject:
Medicine And Pharmacology,
Transplantation
Keywords:
Keywords. Sodium-glucose- cotransporters type 2 inhibitors, glucose reabsorption, sodium reabsorption, randomized clinical trials, diabetes, heart failure, chronic kidney disease, kidney transplantati
Online: 27 May 2024 (14:31:30 CEST)
REVIEW
|
doi:10.20944/preprints202404.1806.v1
Subject:
Social Sciences,
Psychiatry And Mental Health
Keywords:
resilience; longitudinal studies; adverse childhood experiences; trauma; clinical social work; strengths-based practice; resilience assessment; resilience interventions; community resilience; social work education
Online: 28 April 2024 (08:13:19 CEST)
ARTICLE
|
doi:10.20944/preprints202311.0395.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Oncotype; Recurrence Score; breast cancer; genomic risk; chemotherapy; genomic assay; Exact Sciences; Oncotype RS; Oncotype DX; clinical risk; chnages in chemotherapy; TAILORx
Online: 7 November 2023 (10:35:34 CET)
CASE REPORT
|
doi:10.20944/preprints202304.0775.v1
Subject:
Medicine And Pharmacology,
Dermatology
Keywords:
facial rejuvenation; Stromal Vascular Fraction; adipose derived mesenchymal stem cells; autologous adipose tissue graft; Superficial Enhanced Fluid Fat Injection; clinical regeneration applications
Online: 23 April 2023 (05:01:28 CEST)
ARTICLE
|
doi:10.20944/preprints202406.2005.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
Analytical Validation; Barrett’s Esophagus (BE); College of American Pathologists (CAP); Clinical Laboratory Improvement Amendments (CLIA); Cyclin A1 (CCNA1); Vimentin (VIM); DNA Methylation Biomarker
Online: 28 June 2024 (06:01:53 CEST)
REVIEW
|
doi:10.20944/preprints202402.1738.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
Antisense oligonucleotides (ASOs); motor neuron diseases; spinal muscular atrophy; amyotrophic lateral sclerosis; spinal and bulbar muscular atrophy; innovative therapy; nusinersen; tofersen; clinical trals
Online: 1 March 2024 (03:10:14 CET)
ARTICLE
|
doi:10.20944/preprints202312.0550.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
skin health; nutraceuticals; marine hydrolyzed collagen; marine collagen peptides; chondroitin sulfate; glycosaminoglycans; proteomics; wound healing; primary cells; human dermal fibroblasts; clinical; ex vivo
Online: 8 December 2023 (07:53:19 CET)
ARTICLE
|
doi:10.20944/preprints202306.1370.v1
Subject:
Physical Sciences,
Radiation And Radiography
Keywords:
adolescent idiopathic scoliosis; pose estimation; posture parameters; mobile devices; deep learning; clinical photography; mobile applications; MoveNet, convolutional neural network; kinematics; posture; reliability; validity
Online: 19 June 2023 (14:27:12 CEST)
ARTICLE
|
doi:10.20944/preprints202306.0569.v1
Subject:
Public Health And Healthcare,
Physical Therapy, Sports Therapy And Rehabilitation
Keywords:
red flags; clinical reasoning; back pain; cauda equina syndrome; spinal fracture; spinal infection; malignancy; serious pathology; Spinal pain; low back pain; diagnostic triage
Online: 8 June 2023 (07:25:53 CEST)
ARTICLE
|
doi:10.20944/preprints202402.0355.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Mn porphyrin clinical candidate, MnTnBuOE-2-PyP5+ (BMX-001, MnBuOE); Single-cell RNA sequencing; Tumor heterogeneity; Tumor microenvironment; Radiotherapy; Tumor radiosensitization
Online: 6 February 2024 (09:43:28 CET)
REVIEW
|
doi:10.20944/preprints202406.0790.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
Information Systems; Artificial Intelligence; Healthcare; Clinical Decision Support Systems; Predictive Analytics; Natural Language Processing; Computer-aided /diagnostics; Robot-assisted Surgery; Virtual Health Assistants and Chatbots
Online: 12 June 2024 (11:20:20 CEST)
ARTICLE
|
doi:10.20944/preprints202401.1915.v1
Subject:
Medicine And Pharmacology,
Veterinary Medicine
Keywords:
Equine; mesenchymal stem/stromal cells; synovial membrane mesenchymal stem cell; umbilical cord conditioned medium; clinical case; cartilage; subchondral bone; osteoarthritis; allogeneic cell-based therapies; horses.
Online: 26 January 2024 (13:56:06 CET)
ARTICLE
|
doi:10.20944/preprints202311.0744.v1
Subject:
Engineering,
Bioengineering
Keywords:
NIRS; Frailty; active stand; Frailty Phenotype; Frailty Index; Clinical Frailty Scale; cardiovascular; cerebrovascular; neurocardiovascular; statistical parametric mapping; SPM; blood pressure; heart rate; brain oxygenation; TSI
Online: 13 November 2023 (10:50:07 CET)
REVIEW
|
doi:10.20944/preprints202103.0373.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Mesenchymal stem/stromal cells; regenerative medicine; tissue engineering; Clinical Application; Differentiation Capacity; Cellular Immunomodulation; Inflammation; Signaling Cells; Transplantation; International Society for Cell and Gene Therapy
Online: 15 March 2021 (11:51:28 CET)
REVIEW
|
doi:10.20944/preprints202006.0078.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
COVID-19; vaccine; vaccine development; vaccine discovery; systems biology; machine learning; platform technologies; adjuvants; smart clinical trials; human genetics; regulatory convergence; real world evidence; vaccines safety
Online: 7 June 2020 (10:11:02 CEST)
REVIEW
|
doi:10.20944/preprints202305.0658.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
Nanotechnology application; nano-suspension techniques; nano-emulsion techniques; bioactive constituents of plant; phytochemicals (PHYs); poor water solubility; drug delivery systems (DDSs); toxicological risks of NPs; clinical application of NPs
Online: 9 May 2023 (12:50:27 CEST)
ARTICLE
|
doi:10.20944/preprints202203.0403.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
behavioral change prediction; learned features; deep feature learning; handcrafted features; bidirectional long-short term memory; autoencoders; temporal convolutional neural network; clinical decision support system; multisensory stimulation therapy; physiological signals.
Online: 31 March 2022 (08:38:58 CEST)
REVIEW
|
doi:10.20944/preprints202310.0678.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
adaptive immunity to COVID-19; clinical vaccine trials; COVID-19; COVID-19 vaccines; innate immunity to COVID-19; mucosal vaccines; nasal vaccines; SARS-CoV-2; upper respiratory tract immunity; vaccine safety
Online: 11 October 2023 (10:52:38 CEST)
REVIEW
|
doi:10.20944/preprints202211.0271.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
cisplatin; carboplatin; oxaliplatin; cellular uptake; DNA damage; transcription regulation; non-nuclear targets; chemoresistance; mechanisms of action; clinical usages; influx and efflux pumps; ribosome biogenesis; ER stress response; immunogenic cell death; interstrand and intrastrand DNA cross-links.
Online: 15 November 2022 (03:38:06 CET)
REVIEW
|
doi:10.20944/preprints202405.0500.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
Gilbert’ s syndrome (GS), Genetic variations, Protective effects of Gilbert’ s syndrome, Cancer risk, Drug interactions, Pharmacokinetic abnormalities, Clinical implications of Gilbert’ s Syndrome, Effect on NASH, Liver transplantation, Psychology and GS
Online: 9 May 2024 (02:57:19 CEST)
REVIEW
|
doi:10.20944/preprints202405.0601.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Data science; Big data; Data mining; Bioinformatics; Chemometric; Medicinal chemistry; Targets; Knowledge discovery; Artificial intelligence, Machine learning, Deep learning; Data integration; Metadata, Database; QSAR; Collaborative drug discovery; Structure-based drug design; Ligand-based drug discovery; Clinical trials; Product development.
Online: 10 May 2024 (10:15:20 CEST)
ARTICLE
|
doi:10.20944/preprints202401.1406.v1
Subject:
Biology And Life Sciences,
Parasitology
Keywords:
Leishmania infectivity in mammalian hosts; inserts of leishmaniases and coinfections in companion animals; clinical and histopathologic features of natural zoonotic canine leishmaniasis; cell communication by parasite-derived extracellular vesicles; in vitro models advance to target parasite-secreted lipid bound vesicles
Online: 19 January 2024 (03:14:14 CET)
ARTICLE
|
doi:10.20944/preprints202211.0236.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
Acute exacerbation chronic obstructive pulmonary disease (AECOPD); platelet-to-lymphocyte ratio (PLR); neutrophil-to-lymphocyte ratio (NLR); monocyte-to-lymphocyte ratio (MLR); baso-phil-to-lymphocyte ratio (BLR); eosinophil-to-lymphocyte ratio (ELR); in-hospital mortality; nom-ogram; decision curve analysis (DCA); clinical impact curve (CIC)
Online: 14 November 2022 (04:42:59 CET)
ARTICLE
|
doi:10.20944/preprints202407.2002.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
Logistic Regression Model; Post-operative Mortality; Emergency Cardiac Surgeries; Predictive Accuracy; Clinical Decision-Making; ASA Classification; Elixhauser Comorbidity Index; Preoperative Factors; AUROC (Area Under the Receiver Operating Characteristic Curve); AUPRC (Area Under the Precision-Recall Curve); Model Performance Metrics; Preoperative Prothrombin Time; Traditional Risk Assessment Tools; Tertiary Hospital Data; Patient Outcomes
Online: 25 July 2024 (09:39:22 CEST)