REVIEW
|
doi:10.20944/preprints202305.1789.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
PTK6; Colorectal cancer; Tyrosine Kinase Inhibitors
Online: 25 May 2023 (09:52:24 CEST)
ARTICLE
|
doi:10.20944/preprints201908.0177.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
chronic myeloid leukemia; tyrosine kinase inhibitor; adverse drug event; quality of life; second-generation tyrosine kinase inhibitor; nilotinib
Online: 16 August 2019 (08:09:07 CEST)
ARTICLE
Subject:
Computer Science And Mathematics,
Mathematical And Computational Biology
Keywords:
c-src-tyrosine kinase; QSAR; molecular descriptors; virtual screening; drug discovery; cancer; molecular docking
Online: 25 October 2019 (11:21:43 CEST)
REVIEW
|
doi:10.20944/preprints202307.0990.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Bruton's tyrosine kinase (BTK); cognitive disorders; multiple sclerosis (MS); Neuroinflammation; immune system
Online: 14 July 2023 (13:24:12 CEST)
ARTICLE
|
doi:10.20944/preprints202407.2128.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
metastatic renal cell carcinoma; tyrosine kinase inhibitor sunitinib; nomogram; cancer-specific survival; prognosis; treatment response
Online: 26 July 2024 (06:23:32 CEST)
REVIEW
|
doi:10.20944/preprints202112.0282.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Acalabrutinib; Bruton’s tyrosine kinase; BTK; CLL; Covalent inhibitors; COVID-19; Ibrutinib; Non-covalent inhibitors; Fenebrutinib; MK1026; Pirtobrutinib; Spebrutinib; Tirabrutinib; Zanubrutinib
Online: 16 December 2021 (16:13:54 CET)
REVIEW
|
doi:10.20944/preprints202107.0353.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Lung cancer; Adjuvant treatment; Non-small-cell lung carcinoma (NSCLC); Epidermal growth factor receptor (EGFR); Tyrosine kinase inhibitor (TKI)
Online: 15 July 2021 (10:16:30 CEST)
ARTICLE
|
doi:10.20944/preprints201905.0145.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Sprouty1; proliferation; tyrosine kinase
Online: 13 May 2019 (08:23:54 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0638.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
18F-FDG PET/CT; contrast-enhanced CT; melanoma; metastases; tyrosine kinase inhibitors; Immune checkpoint inhibitors; follow-up; therapy monitoring
Online: 26 May 2021 (13:14:06 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
18F-FDG PET/CT; contrast-enhanced CT; melanoma; metastases; tyrosine kinase inhibitors; Immune checkpoint inhibitors; follow-up; therapy monitoring
Online: 25 January 2021 (15:01:17 CET)
ARTICLE
|
doi:10.20944/preprints202104.0732.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Epidermal Growth Factor Receptor (EGFR); mutations, EGFR tyrosine kinase inhibitor; molecular epidemiology; Non-small-cell lung cancer
Online: 28 April 2021 (07:55:22 CEST)
ARTICLE
|
doi:10.20944/preprints202312.1123.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
macrophages; oxidative stress; tyrosine isomers; pAkt, insulin resistance
Online: 15 December 2023 (03:39:52 CET)
BRIEF REPORT
|
doi:10.20944/preprints202309.1238.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
IDO2; lung adenocarcinoma; A549; membrane localization; tyrosine-phosphorylation
Online: 19 September 2023 (04:21:41 CEST)
REVIEW
|
doi:10.20944/preprints201809.0435.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
Acute Myeloid Leukemia; FLT3; Tyrosine kinase inhibitors; resistance
Online: 21 September 2018 (10:28:34 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0417.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
Cysteamine HCl; motor coordination; olfaction; rotarod; tyrosine hydroxylase; Parkinsonism
Online: 10 June 2024 (12:36:48 CEST)
ARTICLE
|
doi:10.20944/preprints202308.2205.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
sperm selection; oxygen consumption; Cumulus cells; Capacitation; Tyrosine phosphorylation
Online: 1 September 2023 (13:43:58 CEST)
REVIEW
|
doi:10.20944/preprints202307.0539.v3
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
Hepatocellular carcinoma; tyrosine kinase inhibitors; immune checkpoint inhibitors; biomarkers
Online: 17 July 2023 (13:22:33 CEST)
REVIEW
|
doi:10.20944/preprints202306.1643.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
metastasis treatment; small molecules; tyrosine kinase inhibitors; integrins; siRNA
Online: 22 June 2023 (16:10:15 CEST)
ARTICLE
|
doi:10.20944/preprints202011.0162.v1
Subject:
Engineering,
Automotive Engineering
Keywords:
Posttranslational modifications (PTMs); Protein tyrosine sulfation (PTS); Protein–protein interaction
Online: 3 November 2020 (14:36:25 CET)
REVIEW
|
doi:10.20944/preprints202003.0251.v2
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
gastric acid suppressant; chemotherapy; tyrosine kinase inhibitors; proton pump inhibitors
Online: 31 March 2020 (03:40:46 CEST)
REVIEW
|
doi:10.20944/preprints202304.1236.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
FLT3 mutations; resistant/relapsed acute myeloid leukemia; tyrosine kinase inhibitors; gilteritinib
Online: 29 April 2023 (10:55:21 CEST)
REVIEW
|
doi:10.20944/preprints201801.0148.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
DCP-LA; PKCε; protein tyrosine phosphatase 1B; Akt; GSK-3β; tauopathy
Online: 17 January 2018 (05:26:21 CET)
ARTICLE
|
doi:10.20944/preprints201709.0082.v1
Subject:
Medicine And Pharmacology,
Dietetics And Nutrition
Keywords:
tyrosine; dose-response; aging; working memory; plasma amino acids; catecholamines; dopamine
Online: 18 September 2017 (15:48:07 CEST)
ARTICLE
|
doi:10.20944/preprints202304.0406.v1
Subject:
Medicine And Pharmacology,
Dietetics And Nutrition
Keywords:
tyrosine; Locus Coeruleus; protein intake; attention; grey matter; neuroimaging; diet; healthy aging
Online: 17 April 2023 (05:00:06 CEST)
ARTICLE
|
doi:10.20944/preprints202111.0479.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Blood-Brain Barrier; Neurodegeneration; obesity; high-fat diet; protein tyrosine phosphatase 1b
Online: 25 November 2021 (13:54:27 CET)
ARTICLE
|
doi:10.20944/preprints201611.0121.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
tissue microarray; immunohistochemistry; cancer imaging; tyrosine kinase receptor; normal tissue; colon cancer
Online: 24 November 2016 (11:07:23 CET)
ARTICLE
|
doi:10.20944/preprints202405.1174.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Gastric cancer; Proto-Oncogene Protein c-met; Tyrosine Kinase Inhibitors; Cell Line; Tumor
Online: 17 May 2024 (12:28:09 CEST)
REVIEW
|
doi:10.20944/preprints202402.0350.v1
Subject:
Public Health And Healthcare,
Physical Therapy, Sports Therapy And Rehabilitation
Keywords:
Phenylketonuria; protein substitutes; amino acid; glycomacropetides; phenyalanine; tyrosine; physical activity; supplement regimens; adherence
Online: 6 February 2024 (08:38:06 CET)
ARTICLE
|
doi:10.20944/preprints202312.0595.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
chronic myeloid leukemia; tyrosine kinase inhibitor; very elderly; safety; efficacy; outcome; dose optimization
Online: 8 December 2023 (10:26:16 CET)
ARTICLE
|
doi:10.20944/preprints202306.1297.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
Heart failure; β-adrenergic receptor; cardiac fibrosis; cardiac inflammation; Bruton’s tyrosine kinase; Zanubrutinib
Online: 19 June 2023 (05:23:12 CEST)
REVIEW
|
doi:10.20944/preprints201808.0044.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
breast tumor kinase (BRK); protein tyrosine kinase 6 (PTK6); breast cancer; pathways; therapeutics
Online: 2 August 2018 (09:58:55 CEST)
REVIEW
|
doi:10.20944/preprints202112.0518.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
B-cell non-Hodgkin lymphoma (B-NHL); B-cell receptor (BCR); Bruton’s tyrosine kinase (BTK); spleen tyrosine kinase (SYK); phosphoinositide-3-kinase (PI3K); ibrutinib; acalabrutinib; copanlisib; idelalisib; umbralisib; fostamatinib; combination therapies
Online: 31 December 2021 (12:23:29 CET)
REVIEW
|
doi:10.20944/preprints202312.0095.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
Eosinophilia,; hematological neoplasm; myeloid/lymphoid neoplasm with eosinophilia; tyrosine kinase fusion genes; acute leukemia
Online: 1 December 2023 (16:34:12 CET)
ARTICLE
|
doi:10.20944/preprints202311.0018.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
protein tyrosine phosphatases; polymerase and histidinol phosphatases; Cap8C; Wzb; metal ion activation; thermophilic enzymes
Online: 1 November 2023 (09:49:36 CET)
REVIEW
|
doi:10.20944/preprints202203.0274.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
dopamine; locus coeruleus; melanin; neuromelanin; norepinephrine; Parkinson’s disease; substan-tia nigra; tyrosinase; tyrosine hydroxylase
Online: 21 March 2022 (05:14:47 CET)
REVIEW
|
doi:10.20944/preprints201705.0212.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
cancer; cell-surface receptor; EGFR; molecular mechanism; phosphorylation; receptor tyrosine kinase; transmembrane signal transduction
Online: 30 May 2017 (08:34:04 CEST)
REVIEW
|
doi:10.20944/preprints202311.1503.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
receptor-type protein tyrosine phosphatases (RPTPs); CD148; R3 subgroup; Extracellular domain (ECD); Fibronectin; Polymorphisms; AlphaFold
Online: 23 November 2023 (10:53:39 CET)
ARTICLE
|
doi:10.20944/preprints202311.0522.v1
Subject:
Medicine And Pharmacology,
Endocrinology And Metabolism
Keywords:
Rabson-Mendenhall syndrome; insulin resistance; diabetes mellitus; acanthosis nigricans; tyrosine kinase; insulin; Insulin receptor; INSR
Online: 8 November 2023 (07:35:08 CET)
REVIEW
|
doi:10.20944/preprints202312.0834.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
Substantia nigra; dopamine; tyrosine hydroxylase; dopamine receptor; striatum; reuptake; phosphorylation; nigrostriatal; Parkinson’ s disease; aging
Online: 12 December 2023 (08:24:58 CET)
REVIEW
|
doi:10.20944/preprints202106.0609.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Chronic myeloid leukaemia; chronic phase; Tyrosine kinase inhibitor; Treatment free remission; deep molecular response; BCR-ABL.
Online: 25 June 2021 (08:13:40 CEST)
REVIEW
|
doi:10.20944/preprints202405.0212.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Hepatocellular carcinoma (HCC); systemic therapies; bridging; liver transplantation (LT); Tyrosine Kinase Inhibitors (TKIs); Immune Checkpoint Inhibitors (ICIs)
Online: 6 May 2024 (04:52:05 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0868.v1
Subject:
Chemistry And Materials Science,
Physical Chemistry
Keywords:
Chemically induced nuclear polarization (CIDNP); guanosine monophosphate; tyrosine anion; short-lived radicals; degenerate electronic exchange; Marcus theory
Online: 10 August 2023 (12:44:20 CEST)
REVIEW
|
doi:10.20944/preprints202012.0288.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
desmoplastic small round cell tumor; treatment; prognosis; surgery; radiotherapy; chemotherapy; tyrosine kinase receptor; target therapy; rare disease
Online: 11 December 2020 (15:53:20 CET)
ARTICLE
|
doi:10.20944/preprints202403.1686.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
lung adenocarcinoma; drug-tolerant persister (DTP) cells; intrinsic resistance; tyrosine kinase inhibitors (TKIs); erlotinib; osimertinib; senescent cells; CD74
Online: 28 March 2024 (12:16:57 CET)
REVIEW
|
doi:10.20944/preprints202305.0122.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Non-small cell lung cancer (NSCLC); EGFR; Tyrosine kinase inhibitors (TKIs); Uncommon mutation; Compound mutation; Intracranial activity; Immunotherapy
Online: 3 May 2023 (09:29:08 CEST)
REVIEW
|
doi:10.20944/preprints202306.0090.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
brain tumor diagnosis; PET; radiolabeled amino acids; O-(2-[18F]fluoroethyl)-L-tyrosine (FET); Hybrid PET/MRI; multimodal imaging
Online: 1 June 2023 (12:54:09 CEST)
ARTICLE
|
doi:10.20944/preprints202012.0582.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Liquid-based 3D culture; tumoroid; cisplatin resistance; imatinib (gleevec); tyrosine kinase inhibitor (TKI); organoid; spheroid; metastatic colorectal cancer (mCRC)
Online: 23 December 2020 (10:15:46 CET)
CASE REPORT
|
doi:10.20944/preprints202406.1544.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
CFS (chronic fatigue syndrome), POTS (postural orthostatic tachycardia syndrome), stress, (COMT) catechol-O-methyltransferase, adrenaline, inflammation, AMPT (alpha-methyl-p-tyrosine)
Online: 21 June 2024 (14:43:51 CEST)
ARTICLE
|
doi:10.20944/preprints202002.0234.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
adeno-associated virus; protein sequence analysis; overlapping genes; amino acid depletion; cysteine depletion; tyrosine depletion; capsid design; membrane-binding amphipathic helix
Online: 17 February 2020 (02:42:39 CET)
ARTICLE
|
doi:10.20944/preprints202212.0542.v2
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
safety analysis; targeted therapy; monoclonal antibody therapy; immune checkpoint inhibibitors; tyrosine kinase inhibitors; breast cancer; gynecological cancer; Helixor; Viscum album L.; PARP inhibitors; CDK 4/6 inhibitors
Online: 30 December 2022 (12:00:35 CET)
REVIEW
|
doi:10.20944/preprints202407.1534.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
lymphoma; B‐cell; hematologic neoplasms; bruton tyrosine kinase; protein kinase inhibitors; drug resistance; neoplasm; ibrutinib; pirtobrutinib; molecular targeted therapy; chronic lymphocytic leukemia; hematopoietic stem cell transplantation; covalent inhibitors; protein degradation
Online: 18 July 2024 (17:24:05 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0122.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Tissue agnostic drug development; Pembrolizumab; Microsatellite instability-high (MSI-H); Tumor mutational burden-high (TMB-H); Dostarlimab-gxly; Larotrectinib; Entrectinib; Neurotrophic tyrosine kinase (NTRK); Dabrafenib and trametinib; V-Raf Murine Sarcoma Viral Oncogene Homolog B V600E (BRAFV600E); Selpercatinib; Rearranged during transfection (RET); Precision oncology.
Online: 3 June 2024 (16:08:38 CEST)