ARTICLE
|
doi:10.20944/preprints202305.1693.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
Digital twin; Clinical trials; Quality by Design; Blockchain technology; Drug development
Online: 24 May 2023 (04:46:13 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1006.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Melanoma; drug discovery; spliceosomal inhibition; BRAF; cell line xenograft; organ histopathology
Online: 15 May 2023 (09:19:54 CEST)
ARTICLE
|
doi:10.20944/preprints202305.0332.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
Ophthalmology; Toxicology Pharmacology and therapeutics; Drug interactions; Pharma-cology and therapeutics
Online: 5 May 2023 (08:56:37 CEST)
REVIEW
|
doi:10.20944/preprints202304.1108.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
biopolymers; nanogels; drug delivery; polysaccharide-based nanogels; protein-based nanogels; nanotechnology
Online: 28 April 2023 (04:32:57 CEST)
ARTICLE
|
doi:10.20944/preprints202304.0569.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Olaparib; self-microemulsifying drug delivery system; microemulsion; solubility; dissolution; oral absorption
Online: 19 April 2023 (08:16:05 CEST)
ARTICLE
|
doi:10.20944/preprints202302.0100.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
mesenchymal stem cell; drug delivery; surface modification; electrostatic interaction; magnetic liposome
Online: 6 February 2023 (10:07:55 CET)
REVIEW
|
doi:10.20944/preprints202212.0581.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Japanese encephalitis (JE); Japanese Encephalitis Virus (JEV); Therapeutics; Vaccine; Antiviral; Drug
Online: 30 December 2022 (09:57:27 CET)
BRIEF REPORT
|
doi:10.20944/preprints202211.0063.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
melanoma; drug discovery; spliceosomal inhibition; acute toxicity; blood chemistry; organ histopathology
Online: 3 November 2022 (01:43:05 CET)
ARTICLE
|
doi:10.20944/preprints202210.0219.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Endometriosis; Orbignya speciosa; Copaifera lansgdorffii nanoemulsion; self-nanoemulsifying drug delivery system
Online: 17 October 2022 (02:07:50 CEST)
REVIEW
|
doi:10.20944/preprints202210.0148.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
drug development; high throughput screening; in vivo/in silico screening; zebrafish
Online: 11 October 2022 (10:33:33 CEST)
REVIEW
|
doi:10.20944/preprints202210.0142.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
bioactive compounds; anthocyanins; drug delivery system; nanoparticles; chronic diseases; health benefits
Online: 11 October 2022 (05:04:19 CEST)
REVIEW
|
doi:10.20944/preprints202208.0180.v1
Subject:
Medicine And Pharmacology,
Psychiatry And Mental Health
Keywords:
Nitrous Oxid; N₂O; nangs; systematic review; harm reduction; drug use
Online: 9 August 2022 (11:29:40 CEST)
COMMUNICATION
|
doi:10.20944/preprints202208.0039.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Echovirus; enterovirus; broad-spectrum antiviral agent; antiviral drug combination; antiviral strategy
Online: 2 August 2022 (05:01:21 CEST)
REVIEW
|
doi:10.20944/preprints202206.0333.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
hPSCs derived-organoids; Culture strategy; Disease modeling; Drug screening; Regenerative therapy
Online: 24 June 2022 (08:11:15 CEST)
REVIEW
|
doi:10.20944/preprints202201.0117.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
G protein-coupled receptor; mouse models; skin cancer; UVR; drug; network
Online: 10 January 2022 (13:41:08 CET)
REVIEW
|
doi:10.20944/preprints202110.0069.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
biology; drug resistance; gene expression profiling; mRNA; multiple myeloma; prognosis; treatment
Online: 5 October 2021 (08:20:44 CEST)
ARTICLE
|
doi:10.20944/preprints202110.0021.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
chitosan; dexketoprofen trometamol; drug delivery; gelatin; NSAIDs; personalized medicine; smart polymers
Online: 1 October 2021 (13:53:53 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Otolaryngology
Keywords:
Drug-induced hearing loss; cochlea; outer hair cells; hearing protection; SIRT3
Online: 9 August 2021 (07:50:36 CEST)
ARTICLE
|
doi:10.20944/preprints202108.0031.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
antibiotics; antimicrobial resistance; antimicrobial stewardship; AWaRe; Pharmacovigilance; Lareb; adverse drug reactions
Online: 2 August 2021 (12:27:02 CEST)
ARTICLE
|
doi:10.20944/preprints202107.0246.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
influenza virus; virus-host interaction; commonly prescribed drugs; drug adverse reaction
Online: 12 July 2021 (11:37:07 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0308.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Indonesia; biodiversity; novel antibiotics; drug screening; bioactivity; gene cluster networking; GNPS
Online: 13 May 2021 (14:05:00 CEST)
ARTICLE
|
doi:10.20944/preprints202012.0534.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
creatinine; vancomycin; amikacin; renal impairment; acute kidney injury; adverse drug reaction
Online: 21 December 2020 (15:42:59 CET)
ARTICLE
|
doi:10.20944/preprints202012.0358.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
Antitumor agents; Fluorescence lifetime imaging; Medicinal chemistry; Metabolic drug; Mitochondrial carrier
Online: 15 December 2020 (08:35:30 CET)
ARTICLE
|
doi:10.20944/preprints202011.0610.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Artesunate; Drug resistance; Malaria; Quinine; Rapid diagnostic test; Plasmodium falciparum; Sahel
Online: 24 November 2020 (09:51:45 CET)
ARTICLE
|
doi:10.20944/preprints202009.0205.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Franz-Bampa; BCS drugs; biomimetic membrane; Franz cell; passive drug transport
Online: 9 September 2020 (10:25:54 CEST)
REVIEW
|
doi:10.20944/preprints202008.0729.v2
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
p53; p73; MDM2; MDMX; tumor suppressor; drug repurposing; aspirin; protoporphyrin IX; verteporfin
Online: 17 September 2020 (07:23:37 CEST)
REVIEW
|
doi:10.20944/preprints202007.0478.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Bioinformatics; Drug Design; Small Organic Molecule; Target identification; Web-based Server
Online: 25 July 2020 (17:50:30 CEST)
ARTICLE
|
doi:10.20944/preprints202006.0358.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Enzyme inhibition; Secondary Metabolites; In-silico Analysis; Molecular docking; Drug candidates
Online: 30 June 2020 (08:11:28 CEST)
HYPOTHESIS
|
doi:10.20944/preprints202004.0215.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
endocanabinoid system; sleep deprivation; animal models; psychosis-like symptoms; drug development
Online: 14 April 2020 (06:28:23 CEST)
CONCEPT PAPER
|
doi:10.20944/preprints202004.0213.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
covid-19; rlmE MTase; new drug target; corona diagnosis; corona pandemic
Online: 13 April 2020 (12:33:22 CEST)
REVIEW
|
doi:10.20944/preprints202004.0012.v1
Subject:
Chemistry And Materials Science,
Theoretical Chemistry
Keywords:
chemoinformatics; chemical space; database; LANaPD; molecular diversity; drug discovery; natural sources
Online: 2 April 2020 (04:47:13 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
humans; infection control; therapy; coronavirus; immunoglobulins; drug therapy; therapeutic use; corticosteroid
Online: 8 March 2020 (17:04:19 CET)
ARTICLE
|
doi:10.20944/preprints201911.0104.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
chemical synthesis; IC50; ED50; CC50; antimalarial resistance; sarcosine-aniline hybrid drug
Online: 10 November 2019 (10:10:15 CET)
REVIEW
Subject:
Medicine And Pharmacology,
Anesthesiology And Pain Medicine
Keywords:
pharmacology; drug development; sodium channel; potassium channel; TRP channel; HCN channels
Online: 8 August 2019 (12:31:26 CEST)
ARTICLE
|
doi:10.20944/preprints201901.0250.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
drug delivery system, muscle atrophy, nanoparticle, prostaglandin E1, sciatic nerve injury
Online: 24 January 2019 (08:51:02 CET)
ARTICLE
|
doi:10.20944/preprints201809.0558.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
Alginate, Chitosan, Layer-by-layer, Magnetic nanoparticles, Drug delivery, Cancer, Curcumin
Online: 28 September 2018 (09:26:48 CEST)
HYPOTHESIS
|
doi:10.20944/preprints201808.0127.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Big Data, Systems Models, Cancer metabolism, Cancer personalized treatment, Drug Discovery.
Online: 6 August 2018 (15:09:15 CEST)
ARTICLE
|
doi:10.20944/preprints201806.0192.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
β4-galactosyltransferase 4; transcriptional mechanism; sensor cells; colon cancer; drug screening
Online: 12 June 2018 (12:51:07 CEST)
REVIEW
|
doi:10.20944/preprints201805.0378.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
annexins; inflammation; wound healing; host-pathogen interplay; drug target; translational research
Online: 27 May 2018 (11:32:34 CEST)
ARTICLE
|
doi:10.20944/preprints201804.0310.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
primary open angle glaucoma; dorzolamide/timolol fixed combination; drug efficacy; safety
Online: 24 April 2018 (08:36:58 CEST)
ARTICLE
|
doi:10.20944/preprints201711.0090.v1
Subject:
Medicine And Pharmacology,
Dentistry And Oral Surgery
Keywords:
drug delivery; dentine; diffusion; bio-active molecules; CFD; μ-LIF; microfluidics
Online: 14 November 2017 (10:15:29 CET)
ARTICLE
|
doi:10.20944/preprints202407.2133.v1
Subject:
Biology And Life Sciences,
Aquatic Science
Keywords:
resistant Acinetobacter baumannii isolates; wastewater and surface water microbial load; surface water microbiome; pangenome analysis; Southern Romanian cities
Online: 26 July 2024 (05:28:41 CEST)
ARTICLE
|
doi:10.20944/preprints202407.1031.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
18F-Fluorocholine PET/CT; radiomics; Radium-223 dichloride; castration-resistant prostate cancer with bone metastases (CRPC-BM); therapeutic failure; overall survival; nomogram.
Online: 12 July 2024 (11:18:13 CEST)
ARTICLE
|
doi:10.20944/preprints202405.1931.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
Candida auris; Fourier-Transform Infrared Spectroscopy; IR-Biotyper; outbreak; phylogenetic analysis; cluster analysis; multi-resistant fungal pathogen; healthcare associated infections
Online: 29 May 2024 (07:41:46 CEST)
REVIEW
|
doi:10.20944/preprints202405.1628.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
multidrug resistant pathogens; antimicrobial oxidative therapy; reactive oxygen species (ROS); biochar (BC); biochar-derived permanent free radicals (PFRs); advanced oxidation processes (AOPs)
Online: 24 May 2024 (13:19:20 CEST)
ARTICLE
|
doi:10.20944/preprints202304.0610.v1
Subject:
Engineering,
Control And Systems Engineering
Keywords:
power equipment; structural and heat resistant steels; mechanical properties, structural-phase state, acoustic and magnetic characteristics, deformation localization zone, structural-mechanical criterion
Online: 20 April 2023 (05:37:01 CEST)
COMMUNICATION
|
doi:10.20944/preprints202007.0709.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
intrinsic multi-drug resistance; acquired multi-drug resistance; circulating tumor cells; single cells; cell clusters; cell monolayer; multi-cellular spheroids; cytometry of reaction rate constant; ovarian cancer
Online: 30 July 2020 (09:01:50 CEST)
ARTICLE
|
doi:10.20944/preprints202401.0219.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
CRE; ESBL; extended spectrum beta lactamase; non-carbapenemase-producing; ertapenem-resistant; meropenem-susceptible; porin loss; outer-membrane protein; mobile genetic elements; molecular epidemiology
Online: 3 January 2024 (09:43:24 CET)
ARTICLE
|
doi:10.20944/preprints202407.2353.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
cell membrane-derived liposomes; Memposomes; drug delivery vehicle; homologous targeting; E-cadherin
Online: 30 July 2024 (07:45:23 CEST)
REVIEW
|
doi:10.20944/preprints202407.1682.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
pharmacogenetics; blood-brain barrier; drug discovery; personalised medicine; precision medicine; clinical translation
Online: 22 July 2024 (09:54:15 CEST)
ARTICLE
|
doi:10.20944/preprints202407.1667.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
active targeting; CRT peptide; drug delivery; cancer; nanoemulsion
Online: 22 July 2024 (07:50:13 CEST)
ARTICLE
|
doi:10.20944/preprints202406.1032.v1
Subject:
Medicine And Pharmacology,
Endocrinology And Metabolism
Keywords:
Semaglutide Analogues; GLP-1 Receptor Agonists; Binding Affinity Optimization; Computational Drug Design;
Online: 17 June 2024 (09:12:54 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0976.v1
Subject:
Medicine And Pharmacology,
Orthopedics And Sports Medicine
Keywords:
polylactide– polyglycolide; vancomycin; lithium; drug delivery; WNT agonist; mesenchymal stem cells
Online: 14 June 2024 (09:37:05 CEST)
CONCEPT PAPER
|
doi:10.20944/preprints202405.1739.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
Drug Discovery & Design; Synthetic Data Generation; Intermolecular Binding Affinity (Kd); GIBAC
Online: 27 May 2024 (10:49:40 CEST)
REVIEW
|
doi:10.20944/preprints202404.1013.v3
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
computational pharmaceutics; AI; multi-scale modeling; quantum computing; drug discovery; blockchain frameworks
Online: 22 April 2024 (18:38:54 CEST)
REVIEW
|
doi:10.20944/preprints202404.0674.v1
Subject:
Environmental And Earth Sciences,
Other
Keywords:
Microneedles; Bioactive molecules; Transdermal drug delivery system; Design parameters; Manufacturing techniques; Usage
Online: 9 April 2024 (14:52:30 CEST)
ARTICLE
|
doi:10.20944/preprints202403.1775.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Hepatitis B virus; Antivirals; Flavonoid; Drug discovery; Pharmacophore; Quantitative structure-activity relationship
Online: 28 March 2024 (13:31:24 CET)
ARTICLE
|
doi:10.20944/preprints202403.1204.v1
Subject:
Medicine And Pharmacology,
Tropical Medicine
Keywords:
uncomplicated malaria; malaria drug resistance; Multiple-First line Treatment; sub-Saharan Africa
Online: 20 March 2024 (11:34:01 CET)
REVIEW
|
doi:10.20944/preprints202403.0140.v1
Subject:
Medicine And Pharmacology,
Complementary And Alternative Medicine
Keywords:
Cancer Pharmacotherapy; Drug development; Kinesin motor proteins; Microtubules; Mitotic kinases; Mitotic poisons
Online: 4 March 2024 (11:17:25 CET)
REVIEW
|
doi:10.20944/preprints202402.0148.v1
Subject:
Medicine And Pharmacology,
Dentistry And Oral Surgery
Keywords:
medication-related osteonecrosis of the jaw; drug holiday; treatment; tooth extraction; incidence
Online: 2 February 2024 (11:48:46 CET)
REVIEW
|
doi:10.20944/preprints202312.2253.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Ganoderma lucidum; Nanotechnology; Nanoparticles; Triterpenoids; Polysaccharides; Bioactive compounds; Drug delivery; Cancer therapy
Online: 29 December 2023 (11:31:12 CET)
ARTICLE
|
doi:10.20944/preprints202311.1816.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
essential antimicrobials; essential medicine list; drug procurement; gap analysis; paediatric antibiotic formulations
Online: 29 November 2023 (11:04:15 CET)
ARTICLE
|
doi:10.20944/preprints202311.1179.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
reporting; system; chemical; drug overdose; poisoning; surveillance; Makkah Almukarramah; Saudi Arabia
Online: 17 November 2023 (15:04:33 CET)
ARTICLE
|
doi:10.20944/preprints202311.0653.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Cytochrome P450 oxidoreductase; POR; gnomAD, CAH; drug metabolism, steroid hormones; SNV; bioinformatics
Online: 9 November 2023 (15:09:12 CET)
ARTICLE
|
doi:10.20944/preprints202310.0396.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Pyrimidine; Homology Modelling; Pharmacophore Mapping; 3D-QSAR; Molecular Docking; ADMET; Drug Design
Online: 9 October 2023 (09:36:05 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0467.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
pan-cancer analysis; RKIP; YY1; gene expression; mutations; immune infiltration; drug resistance
Online: 7 September 2023 (13:33:14 CEST)
ARTICLE
|
doi:10.20944/preprints202308.2113.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
herbs; spices; flavonoids; antioxidants; diabetes; volatile compounds; drug discovery; phytochemicals; human health
Online: 31 August 2023 (10:12:18 CEST)
ARTICLE
|
doi:10.20944/preprints202307.1905.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Colorectal cancer; pharmacovigilance; BRAF inhibitors; regorafenib; encorafenib; adverse drug reactions; renal disorders
Online: 28 July 2023 (02:34:59 CEST)
ARTICLE
|
doi:10.20944/preprints202307.1577.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
deep learning, transformer, drug use detection, exploratory data analysis, natural language processing.
Online: 24 July 2023 (10:57:47 CEST)
REVIEW
|
doi:10.20944/preprints202306.0220.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
hydrogel-forming microneedles; transdermal drug delivery; controlled release; permeation pathway; environmental response
Online: 2 June 2023 (15:57:01 CEST)
ARTICLE
|
doi:10.20944/preprints202306.0038.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
Lagenaria siceraria; In silico study; Drug design; Diabetes mellitus; Molecular docking; ADMET
Online: 1 June 2023 (05:41:13 CEST)
REVIEW
|
doi:10.20944/preprints202305.1084.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
antibody-drug conjugate; lysosome; cathepsin; legumain; self-immolation; payload release; peptidomimetic; linker
Online: 16 May 2023 (04:51:34 CEST)
REVIEW
|
doi:10.20944/preprints202212.0207.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Blood-Brain Barrier; Brain Drug Delivery; Carbon Nanomaterials; Cerebral Gliomas; Glioblastoma; Nanoparticles.
Online: 12 December 2022 (14:56:45 CET)
ARTICLE
|
doi:10.20944/preprints202212.0170.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
SonoCloud; GL261 mouse model; ultrasound-mediated drug delivery; glioblastoma; immune checkpoint inhibitors
Online: 9 December 2022 (02:59:28 CET)
ARTICLE
|
doi:10.20944/preprints202211.0296.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
antimicrobial resistance; broad-spectrum antibiotics; antibacterial drug discovery; gram-negative bacteria; pyrrolobenzodiazepines
Online: 16 November 2022 (04:20:55 CET)
REVIEW
|
doi:10.20944/preprints202211.0062.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
membrane transporter; SLC; solute carrier; drug design; pharmacokinetics; prodrug; nanoparticle; bile acids
Online: 3 November 2022 (01:09:54 CET)
ARTICLE
|
doi:10.20944/preprints202210.0141.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
AtbFinder; antibiotic susceptibility testing; cystic fibrosis; Pseudomonas aeruginosa; multi-drug re-sistant
Online: 11 October 2022 (04:56:32 CEST)
ARTICLE
|
doi:10.20944/preprints202208.0207.v3
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
Adverse Drug Reaction; Spontaneous reporting; Active surveillance; Underreporting; Antiglau-coma; Artificial tear
Online: 11 October 2022 (03:18:55 CEST)
REVIEW
|
doi:10.20944/preprints202208.0230.v1
Subject:
Chemistry And Materials Science,
Theoretical Chemistry
Keywords:
chemoinformatics; compound databases; chemical space; diversity; drug discovery; openscience; pseudo-natural product
Online: 12 August 2022 (08:39:40 CEST)
ARTICLE
|
doi:10.20944/preprints202206.0183.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
Biomarkers; Drug Signature Identification; Key pathways; Oral Cancer; Oral Squamous Cell Carcinoma
Online: 13 June 2022 (10:14:58 CEST)
ARTICLE
|
doi:10.20944/preprints202111.0364.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
Polymeric micelles; cannabidiol (CBD); spray-drying; ocular drug delivery; corneal epithelial cells
Online: 19 November 2021 (14:48:27 CET)
ARTICLE
|
doi:10.20944/preprints202111.0072.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
antimalarial drugs; artemisinins; ACTs; resistance; amino-artemisinins, pharmacokinetics; metabolism; Cmax; drug efficacy
Online: 3 November 2021 (09:10:50 CET)
ARTICLE
|
doi:10.20944/preprints202106.0279.v1
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
Blood-Brain Barrier, Penetrating Peptides, Machine learning techniques, Drug delivery, Therapeutic peptides
Online: 10 June 2021 (08:13:15 CEST)
REVIEW
|
doi:10.20944/preprints202104.0652.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
Enzymatic reaction; crosslinking; Hydrogel; Biomedical application; Tissue engineering; Wound healing; Drug delivery
Online: 26 April 2021 (10:52:24 CEST)
ARTICLE
|
doi:10.20944/preprints202103.0621.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Auger electron; cisplatin; 191Pt; 189Pt; radio-drug; DNA double-strand break; γH2AX
Online: 25 March 2021 (14:30:14 CET)
CASE REPORT
|
doi:10.20944/preprints202103.0054.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
DRESS syndrome, Eosinophilia, Adverse drug reaction, HHV-6 reactivation, Bactrim adverse reaction
Online: 2 March 2021 (09:26:48 CET)
REVIEW
|
doi:10.20944/preprints202102.0449.v1
Subject:
Chemistry And Materials Science,
Materials Science And Technology
Keywords:
multifunctional; hydrogel nanocomposties; tissue engineering; drug delivery; wound healing; bioprinting; biowearable devices
Online: 22 February 2021 (08:48:20 CET)
ARTICLE
|
doi:10.20944/preprints202012.0513.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
apoferritin nanocarriers; controlled drug delivery; idarubicin; ferritin receptor targeting; folate receptor targeting
Online: 21 December 2020 (11:28:08 CET)
REVIEW
|
doi:10.20944/preprints202012.0242.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
COVID-19; SARS-CoV-2; long-haul; inflammation; tissue damage; drug repurposing
Online: 10 December 2020 (09:42:20 CET)
COMMUNICATION
|
doi:10.20944/preprints202011.0441.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Sars-Cov-2; Proteomic,; Ghost proteome,; Alternative proteins,; AltOrf.; interactomic; drug repurposing
Online: 16 November 2020 (17:50:19 CET)
ARTICLE
|
doi:10.20944/preprints202004.0524.v2
Subject:
Biology And Life Sciences,
Virology
Keywords:
unsupervised learning; tensor decomposition; feature selection; COVID-19; drug discovery; gene expression
Online: 3 June 2020 (05:29:09 CEST)
ARTICLE
|
doi:10.20944/preprints202003.0413.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
coronavirus; drug; COVID-19; SARS; MERS; ontology; ChEBI; NDF-RT; DrON; bioinformatics
Online: 29 March 2020 (01:58:40 CET)
ARTICLE
|
doi:10.20944/preprints202003.0393.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
SARS-CoV2; RNA depended RNA polymerase; Valproic acid Co-A; drug repurposing
Online: 26 March 2020 (15:04:22 CET)
ARTICLE
|
doi:10.20944/preprints202002.0178.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
DILIrank; DILI; drug hepatotoxicity; QSAR; nested cross-validation; virtual screening; in silico
Online: 14 February 2020 (02:24:04 CET)
REVIEW
|
doi:10.20944/preprints201906.0002.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
patient-derived xenograft; immunocompromised mice; precision medicine; drug screening; cancer; cell line
Online: 3 June 2019 (04:47:14 CEST)
ARTICLE
|
doi:10.20944/preprints201810.0381.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Biginelli reaction; dihydropyrimidin-2-thiones; synthesis, virtual screening, drug design; LaSOM 282
Online: 17 October 2018 (09:34:06 CEST)
REVIEW
|
doi:10.20944/preprints201801.0218.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Biocompatibility; Biodegradability; Biopolyesters; Biopolymers; Composites; Drug Release; Implants; Polyhydroxyalkanoates; Scaffolds; Tissue Engineering
Online: 23 January 2018 (16:49:05 CET)
ARTICLE
|
doi:10.20944/preprints201712.0024.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
HIV-1; quasispecies; minority resistance mutations; HAART; drug resistance; undetectable viral load
Online: 4 December 2017 (09:34:16 CET)
ARTICLE
|
doi:10.20944/preprints202105.0480.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
camptothecin; drug distribution; drug-membrane interaction; biophysical profiling; biomimetic models; partition coefficient; ADMET/PK prediction; small and wide-angle X-ray diffraction; fluorescence spectroscopy; human serum albumin (HSA)
Online: 20 May 2021 (10:52:33 CEST)
ARTICLE
|
doi:10.20944/preprints202404.0304.v1
Subject:
Public Health And Healthcare,
Physical Therapy, Sports Therapy And Rehabilitation
Keywords:
Multiple myeloma; Nordic Walking; intermittent fasting; sclerostin; Dickkopf-related protein 1; osteoprotegrin; Tartrate-resistant acid phosphatase 5b; Wnt pathway; vitamin D; cancer rehabilitation; elderly
Online: 3 April 2024 (14:27:03 CEST)