REVIEW
|
doi:10.20944/preprints202305.1084.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
antibody-drug conjugate; lysosome; cathepsin; legumain; self-immolation; payload release; peptidomimetic; linker
Online: 16 May 2023 (04:51:34 CEST)
REVIEW
|
doi:10.20944/preprints202212.0207.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Blood-Brain Barrier; Brain Drug Delivery; Carbon Nanomaterials; Cerebral Gliomas; Glioblastoma; Nanoparticles.
Online: 12 December 2022 (14:56:45 CET)
ARTICLE
|
doi:10.20944/preprints202212.0170.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
SonoCloud; GL261 mouse model; ultrasound-mediated drug delivery; glioblastoma; immune checkpoint inhibitors
Online: 9 December 2022 (02:59:28 CET)
ARTICLE
|
doi:10.20944/preprints202211.0296.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
antimicrobial resistance; broad-spectrum antibiotics; antibacterial drug discovery; gram-negative bacteria; pyrrolobenzodiazepines
Online: 16 November 2022 (04:20:55 CET)
REVIEW
|
doi:10.20944/preprints202211.0062.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
membrane transporter; SLC; solute carrier; drug design; pharmacokinetics; prodrug; nanoparticle; bile acids
Online: 3 November 2022 (01:09:54 CET)
ARTICLE
|
doi:10.20944/preprints202210.0141.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
AtbFinder; antibiotic susceptibility testing; cystic fibrosis; Pseudomonas aeruginosa; multi-drug re-sistant
Online: 11 October 2022 (04:56:32 CEST)
ARTICLE
|
doi:10.20944/preprints202208.0207.v3
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
Adverse Drug Reaction; Spontaneous reporting; Active surveillance; Underreporting; Antiglau-coma; Artificial tear
Online: 11 October 2022 (03:18:55 CEST)
REVIEW
|
doi:10.20944/preprints202208.0230.v1
Subject:
Chemistry And Materials Science,
Theoretical Chemistry
Keywords:
chemoinformatics; compound databases; chemical space; diversity; drug discovery; openscience; pseudo-natural product
Online: 12 August 2022 (08:39:40 CEST)
ARTICLE
|
doi:10.20944/preprints202206.0183.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
Biomarkers; Drug Signature Identification; Key pathways; Oral Cancer; Oral Squamous Cell Carcinoma
Online: 13 June 2022 (10:14:58 CEST)
ARTICLE
|
doi:10.20944/preprints202111.0364.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
Polymeric micelles; cannabidiol (CBD); spray-drying; ocular drug delivery; corneal epithelial cells
Online: 19 November 2021 (14:48:27 CET)
ARTICLE
|
doi:10.20944/preprints202111.0072.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
antimalarial drugs; artemisinins; ACTs; resistance; amino-artemisinins, pharmacokinetics; metabolism; Cmax; drug efficacy
Online: 3 November 2021 (09:10:50 CET)
ARTICLE
|
doi:10.20944/preprints202106.0279.v1
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
Blood-Brain Barrier, Penetrating Peptides, Machine learning techniques, Drug delivery, Therapeutic peptides
Online: 10 June 2021 (08:13:15 CEST)
REVIEW
|
doi:10.20944/preprints202104.0652.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
Enzymatic reaction; crosslinking; Hydrogel; Biomedical application; Tissue engineering; Wound healing; Drug delivery
Online: 26 April 2021 (10:52:24 CEST)
ARTICLE
|
doi:10.20944/preprints202103.0621.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Auger electron; cisplatin; 191Pt; 189Pt; radio-drug; DNA double-strand break; γH2AX
Online: 25 March 2021 (14:30:14 CET)
CASE REPORT
|
doi:10.20944/preprints202103.0054.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
DRESS syndrome, Eosinophilia, Adverse drug reaction, HHV-6 reactivation, Bactrim adverse reaction
Online: 2 March 2021 (09:26:48 CET)
REVIEW
|
doi:10.20944/preprints202102.0449.v1
Subject:
Chemistry And Materials Science,
Materials Science And Technology
Keywords:
multifunctional; hydrogel nanocomposties; tissue engineering; drug delivery; wound healing; bioprinting; biowearable devices
Online: 22 February 2021 (08:48:20 CET)
ARTICLE
|
doi:10.20944/preprints202012.0513.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
apoferritin nanocarriers; controlled drug delivery; idarubicin; ferritin receptor targeting; folate receptor targeting
Online: 21 December 2020 (11:28:08 CET)
REVIEW
|
doi:10.20944/preprints202012.0242.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
COVID-19; SARS-CoV-2; long-haul; inflammation; tissue damage; drug repurposing
Online: 10 December 2020 (09:42:20 CET)
ARTICLE
|
doi:10.20944/preprints202004.0448.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
acetyleugenol; Acacia nilotica; anti-tuberculosis; Serine/Threonine kinases; multi-drug resistant TB
Online: 24 April 2020 (14:12:33 CEST)
ARTICLE
|
doi:10.20944/preprints202003.0413.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
coronavirus; drug; COVID-19; SARS; MERS; ontology; ChEBI; NDF-RT; DrON; bioinformatics
Online: 29 March 2020 (01:58:40 CET)
ARTICLE
|
doi:10.20944/preprints202003.0393.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
SARS-CoV2; RNA depended RNA polymerase; Valproic acid Co-A; drug repurposing
Online: 26 March 2020 (15:04:22 CET)
ARTICLE
|
doi:10.20944/preprints202002.0178.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
DILIrank; DILI; drug hepatotoxicity; QSAR; nested cross-validation; virtual screening; in silico
Online: 14 February 2020 (02:24:04 CET)
REVIEW
|
doi:10.20944/preprints201906.0002.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
patient-derived xenograft; immunocompromised mice; precision medicine; drug screening; cancer; cell line
Online: 3 June 2019 (04:47:14 CEST)
REVIEW
|
doi:10.20944/preprints201801.0218.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Biocompatibility; Biodegradability; Biopolyesters; Biopolymers; Composites; Drug Release; Implants; Polyhydroxyalkanoates; Scaffolds; Tissue Engineering
Online: 23 January 2018 (16:49:05 CET)
ARTICLE
|
doi:10.20944/preprints201712.0024.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
HIV-1; quasispecies; minority resistance mutations; HAART; drug resistance; undetectable viral load
Online: 4 December 2017 (09:34:16 CET)
REVIEW
|
doi:10.20944/preprints202408.1827.v1
Subject:
Mathematical And Computational Biology,
Computer Science And Mathematics
Keywords:
Predictive Toxicology; Omics Technologies; Machine Learning; Structure-Activity Relationship; Fragment-Based Drug Design; Microphysiological Systems; Physiologically Based Pharmacokinetic Modeling; Virtual Screening; Biochemical Targets; Automated De Novo Drug Design
Online: 26 August 2024 (11:31:51 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0480.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
camptothecin; drug distribution; drug-membrane interaction; biophysical profiling; biomimetic models; partition coefficient; ADMET/PK prediction; small and wide-angle X-ray diffraction; fluorescence spectroscopy; human serum albumin (HSA)
Online: 20 May 2021 (10:52:33 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0098.v1
Subject:
Environmental And Earth Sciences,
Geophysics And Geology
Keywords:
Dongjun; Lead-zinc deposit; Pb-Zn ore; Inner Mongolia; Joint inversion; Audio-Magnetotelluric (AMT); Dual frequency Induced Polarization (DFIP)
Online: 3 June 2024 (13:54:03 CEST)
ARTICLE
|
doi:10.20944/preprints202401.0458.v1
Subject:
Physical Sciences,
Nuclear And High Energy Physics
Keywords:
Reaction theory; nuclear many– body theory; double charge exchange reactions; double beta decay; induced interactions; nuclear matrix elements
Online: 5 January 2024 (04:44:26 CET)
ARTICLE
|
doi:10.20944/preprints202311.1861.v1
Subject:
Physical Sciences,
Radiation And Radiography
Keywords:
THz radiation; femtosecond laser-induced breakdown; air breakdown; spatiotemporal control; coupling of temperature; density gradients in plasma; tunnelling ionisation
Online: 29 November 2023 (10:53:19 CET)
ARTICLE
|
doi:10.20944/preprints202310.0692.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
iodixanol; cardiac ct; coronary ct; ccta; contrast media; intravenous contrast media; computed tomography; iodixanol; cardiac catheterization; contrast induced nephropathy
Online: 13 October 2023 (03:23:31 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0350.v3
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
zirconium dioxide; stability; yttrium-stablized ZrO2 (YSZ); oxygen vacancy; enthalpy and entropy; doped-induced phase transition; fermi level shift
Online: 21 September 2023 (09:56:20 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0586.v3
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
zirconium dioxide; stability; yttrium-stabilized ZrO2 (YSZ); oxygen vacancy; enthalpy and entropy; doped-induced phase transition; fermi level shift
Online: 12 September 2023 (16:58:32 CEST)
ARTICLE
|
doi:10.20944/preprints202304.0384.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
pulmonary organoids; induced pluripotent stem cells (iPSCs); anterior foregut endoderm; mesoderm; alveoli epithelial cells; SARS-Cov2; iPSC disease modelling
Online: 17 April 2023 (03:33:39 CEST)
ARTICLE
|
doi:10.20944/preprints202302.0430.v1
Subject:
Physical Sciences,
Astronomy And Astrophysics
Keywords:
diatomic molecules; cyanide; laser-plasma; data analysis; laser induced breakdown spectroscopy; combustion; time-resolved spectroscopy; spectra fitting program; astrophysics
Online: 27 February 2023 (02:28:52 CET)
ARTICLE
|
doi:10.20944/preprints202211.0007.v1
Subject:
Social Sciences,
Cognitive Science
Keywords:
high variability phonetic training (HVPT), categorical perception (CP), cochlear implant (CI), lexical tone, Mandarin-speaking kindergarteners, training-induced gains
Online: 1 November 2022 (01:41:59 CET)
CONCEPT PAPER
|
doi:10.20944/preprints202111.0118.v1
Subject:
Business, Economics And Management,
Accounting And Taxation
Keywords:
Disruptive Technologies; Operational Breakeven; Altman’s Z-score; Enyi’s RSR; Going Concern; Market Induced Survival Ratio; Disruptive Technology Gains Index
Online: 5 November 2021 (11:31:53 CET)
ARTICLE
|
doi:10.20944/preprints202103.0357.v1
Subject:
Engineering,
Automotive Engineering
Keywords:
Geomagnetic induced current (GIC); Magnetic field component (dB/dt); Geomagnetic data (GMD); Corona mass ejections (CMEs); Electric field (E)
Online: 12 March 2021 (23:58:40 CET)
ARTICLE
Subject:
Physical Sciences,
Atomic And Molecular Physics
Keywords:
plasma diagnostics; molecular spectra; diatomic molecules; plasma spectroscopy; laser spectroscopy; laser-induced breakdown spectroscopy; optical emission spectroscopy; hypersonic expansion
Online: 15 January 2020 (07:12:25 CET)
ARTICLE
|
doi:10.20944/preprints201906.0095.v1
Subject:
Physical Sciences,
Optics And Photonics
Keywords:
paracetamol; laser-induced breakdown spectroscopy; cyanide; carbon Swan bands; principal component analysis; Raman spectroscopy; Fourier-Transform-infra-red spectroscopy
Online: 11 June 2019 (10:42:58 CEST)
ARTICLE
|
doi:10.20944/preprints201701.0095.v1
Subject:
Chemistry And Materials Science,
Applied Chemistry
Keywords:
polymeric composite; surface initiated atom transfer radical polymerization; photo-induced; living radical polymerization; metal-free atom transfer radical polymerization
Online: 22 January 2017 (04:56:44 CET)
ARTICLE
|
doi:10.20944/preprints202402.0890.v1
Subject:
Physical Sciences,
Optics And Photonics
Keywords:
Laser-induced breakdown spectroscopy (LIBS); Aluminum (Al); Magnesium (Mg); Manganese (Mn); Chromium (Cr); Copper (Cu); Zinc (Zn); Aluminum Monoxide (AlO).
Online: 16 February 2024 (07:01:12 CET)
REVIEW
|
doi:10.20944/preprints202312.1502.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
ModRNA vaccines trigger autoimmune disorders, Autoimmunity, serious side effects of Covid-19 ModRNA vaccines ,vaccine induced autoimmunity.
Online: 20 December 2023 (09:42:07 CET)
REVIEW
|
doi:10.20944/preprints202309.0860.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
gastrointestinal cancer; immunotherapy; cancer vaccines; dendritic cell vaccine; adoptive cell treatment; cytokine-induced killer cells; immune checkpoint inhibitors; angiogenesis inhibition
Online: 13 September 2023 (10:07:21 CEST)
ARTICLE
|
doi:10.20944/preprints202304.1258.v1
Subject:
Physical Sciences,
Atomic And Molecular Physics
Keywords:
diatomic molecules; aluminum monoxide; laser-plasma; data analysis; laser induced breakdown spectroscopy; combustion; time-resolved spectroscopy; spectra fitting program; astrophysics
Online: 30 April 2023 (04:36:48 CEST)
ARTICLE
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Human induced pluripotent stem cells (hiPSCs); monoclonal antibodies; R-10G; R-17F; keratan sulfate; podocalyxin; keratanase II; endo-β-galactosidase
Online: 9 March 2021 (12:13:56 CET)
ARTICLE
|
doi:10.20944/preprints201911.0237.v1
Subject:
Physical Sciences,
Condensed Matter Physics
Keywords:
co-polymer; polyarylene ether ketones; switching effect; irradiation by electrons; small-signal regime; radiation induced conductivity; dispersive transport; carrier mobility
Online: 20 November 2019 (11:07:30 CET)
ARTICLE
|
doi:10.20944/preprints201906.0134.v1
Subject:
Physical Sciences,
Fluids And Plasmas Physics
Keywords:
atomic and molecular spectroscopy; time-resolved spectroscopy; laser plasma; laser-induced optical breakdown; stellar astrophysics spectra; white dwarf stars; hydrogen
Online: 14 June 2019 (15:01:44 CEST)
ARTICLE
|
doi:10.20944/preprints201804.0087.v1
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
Mongolian oak cups; ethanol crude extract (ECE); ellagic acid- and kaempferol-derivatives; alloxan-induced rats; type 1 diabetes; hypoglycemic effect
Online: 8 April 2018 (08:45:39 CEST)
REVIEW
|
doi:10.20944/preprints202408.0229.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Alzheimer's disease; mesenchymal stem cells; Drug discovery and development; Neurosurgery; Neurology; Novel theapies
Online: 6 August 2024 (05:20:17 CEST)
REVIEW
|
doi:10.20944/preprints202407.2544.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
antioxidants; liver cancer; nano-formulations; drug delivery; natural compounds; hepatocellular carcinoma; oxidative stress
Online: 31 July 2024 (14:02:17 CEST)
ARTICLE
|
doi:10.20944/preprints202407.1733.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
Berberine hydrochloride; Chitosan/Carboxymethyl-β-Cyclodextrin; Hydrogel formulation; Solubility enhancement; Oral drug delivery.
Online: 22 July 2024 (17:36:55 CEST)
ARTICLE
|
doi:10.20944/preprints202407.1116.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Hepatitis C virus; MD Simulations; Covalent inhibitor; Drug resistance; Pharmacophore-based virtual screening
Online: 16 July 2024 (04:54:08 CEST)
COMMUNICATION
|
doi:10.20944/preprints202407.0769.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
Oritavancin; prosthetic joint infections; PJI; therapeutic drug monitoring; TDM; MR; suppressive therapy; outpatient
Online: 10 July 2024 (11:59:23 CEST)
ARTICLE
|
doi:10.20944/preprints202407.0129.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
Atypical antipsychotics (AAPs), secondary drug effects, schizophrenia, liver, mitochondria, oxidative stress (OS), MAPK.
Online: 2 July 2024 (13:23:11 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0953.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
GIBAC; Intermolecular binding affinity (Kd); Structural biophysics; Synthetic data; Drug discovery \& design;
Online: 14 June 2024 (05:04:28 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0761.v1
Subject:
Medicine And Pharmacology,
Complementary And Alternative Medicine
Keywords:
cervical cancer; apoptosis; Arachis hypogaea L.; drug combination; xenograft model; peanut skin extract
Online: 12 June 2024 (12:17:37 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0085.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
precision medicine; drug response prediction; cell-free mRNA; transcriptomic profiling; gene expression signature
Online: 6 June 2024 (03:09:40 CEST)
ARTICLE
|
doi:10.20944/preprints202403.1579.v2
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Multiple Drug Resistant breast cancer; Anaphase Promoting Complex; cell culture; PDX mouse model
Online: 28 March 2024 (13:34:15 CET)
ARTICLE
|
doi:10.20944/preprints202403.0783.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
poly(-caprolactone); electrospinning; nano-hydroxyapatite; Humulus lupulus; hops; drug delivery system; bone regeneration
Online: 13 March 2024 (16:05:00 CET)
ARTICLE
|
doi:10.20944/preprints202403.0717.v1
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
Lumpy skin disease; DNA polymerase; potential inhibitors; phytocompounds; antiviral drug compounds; molecular docking
Online: 13 March 2024 (07:58:39 CET)
ARTICLE
|
doi:10.20944/preprints202401.1398.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Nosocomial infections; Antibacterial activity; Drug resistance; Clausena anisata; GC-MS analysis; Essential oil
Online: 18 January 2024 (11:05:38 CET)
ARTICLE
|
doi:10.20944/preprints202401.1186.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
kidney replacement therapy; medication review; drug-related problems; negative outcomes associated with medication.
Online: 16 January 2024 (13:57:35 CET)
ARTICLE
|
doi:10.20944/preprints202312.2280.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Free-floating organoids; non-small cell lung cancer; cytokine; drug resistance; personalized medicine
Online: 29 December 2023 (13:28:30 CET)
ARTICLE
|
doi:10.20944/preprints202312.2016.v2
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
interpolyelectrolyte complexes; Eudragit® ; gastroretentive systems; drug delivery systems; bioadhesive systems; metronidazole; acyclovir
Online: 27 December 2023 (14:28:59 CET)
ARTICLE
|
doi:10.20944/preprints202312.0574.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
DOCK program; GOLD program; Grb14; insulin receptor (IR); structure-based drug screening (SBDS)
Online: 8 December 2023 (08:24:15 CET)
ARTICLE
|
doi:10.20944/preprints202311.1460.v1
Subject:
Biology And Life Sciences,
Parasitology
Keywords:
Onchocerciasis; drug discovery; anthelmintics; O. gutturosa; motility and MTT inhibition; FDA approved drugs
Online: 23 November 2023 (09:31:11 CET)
ARTICLE
|
doi:10.20944/preprints202311.0766.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Alzheimer's disease; neural networks; Training and learning; early diagnosis; drug discovery; brain diseases
Online: 13 November 2023 (08:41:42 CET)
ARTICLE
|
doi:10.20944/preprints202311.0316.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
levofloxacin; human serum albumin; hydroxypropyl-β-cyclodextrin; conjugate; drug delivery systems; antibacterial activity
Online: 6 November 2023 (07:51:27 CET)
REVIEW
|
doi:10.20944/preprints202310.0771.v1
Subject:
Medicine And Pharmacology,
Psychiatry And Mental Health
Keywords:
Alzheimer's disease; neural networks; Training and learning; early diagnosis; drug discovery; brain diseases
Online: 12 October 2023 (04:19:37 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0417.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
adenylosuccinic acid; Duchenne muscular dystrophy; myopathy; metabolic disease; skeletal muscle; toxicology; drug development
Online: 7 September 2023 (05:09:43 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1966.v1
Subject:
Chemistry And Materials Science,
Theoretical Chemistry
Keywords:
Drug discovery; computational chemistry; conceptual DFT; marine cyclopeptides; chemical reactivity properties; bioavailability scores
Online: 29 August 2023 (09:36:49 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0533.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
therapeutic drug monitoring (TDM); extracorporeal therapies; CKRT; hemoadsorption; cytosorb; antimicrobials; clearance; mass removal
Online: 7 August 2023 (10:46:18 CEST)
ARTICLE
|
doi:10.20944/preprints202307.1535.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
Boswellia Serrata extract; layered double hydroxides; composite; drug delivery system; antimicrobial; anti-inflammatory
Online: 24 July 2023 (10:38:38 CEST)
ARTICLE
|
doi:10.20944/preprints202306.1793.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
bioactive compounds; black sea cucumbers; cancer; drug-target interactions; machine learning; molecular docking
Online: 26 June 2023 (10:36:43 CEST)
ARTICLE
|
doi:10.20944/preprints202304.0800.v1
Subject:
Biology And Life Sciences,
Toxicology
Keywords:
Brushtail possum; Trichosurus vulpecula; fertility control; and drug-metabolising enzymes (CYP3A and UGT2B)
Online: 23 April 2023 (13:11:28 CEST)
ARTICLE
|
doi:10.20944/preprints202301.0076.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
COVID-19; drug repurposing; long COVID; molecular docking; molecular dynamics; SARS-CoV-2
Online: 4 January 2023 (09:38:47 CET)
ARTICLE
|
doi:10.20944/preprints202212.0368.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
Betulinic acid; bovine serum albumin; doxorubicin; drug delivery system; lung cancer; synergistic effect.
Online: 20 December 2022 (10:40:12 CET)
SHORT NOTE
|
doi:10.20944/preprints202212.0230.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
monoamine oxidase; inhibitors; indole; 1,2,4-oxadiazole; drug research; neuroprotective drugs; Parkinson’s disease; MAO
Online: 13 December 2022 (07:12:01 CET)
REVIEW
|
doi:10.20944/preprints202211.0070.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
Nutraceuticals; Personalized Medicine; Precision Medicine; Probiotics; Vitamins; Covid; Dietary Supplements; Adverse Drug Effects
Online: 3 November 2022 (06:27:25 CET)
ARTICLE
|
doi:10.20944/preprints202210.0302.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
poxviruses; monkeypox virus; envelope proteins; drug repurposing; bioactive phytochemicals; molecular docking, molecular simulation
Online: 20 October 2022 (09:32:02 CEST)
ARTICLE
|
doi:10.20944/preprints202208.0317.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
Cytochrome P450; POR; Congenital adrenal hyperplasia; metabolic disorders; CYP3A4; protein stability; drug metabolism
Online: 17 August 2022 (10:02:51 CEST)
ARTICLE
|
doi:10.20944/preprints202112.0203.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
enterovirus; antidepressant sertraline; drug repurposing; viral entry; host-cell targets; broad-spectrum antiviral
Online: 13 December 2021 (12:55:13 CET)
ARTICLE
|
doi:10.20944/preprints202105.0158.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Imatinib; NLC; Tween 80; SLS; MTT Assay; Release study; Drug delivery; Breast cancer
Online: 10 May 2021 (10:13:02 CEST)
REVIEW
|
doi:10.20944/preprints202104.0574.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
smart materials; drug delivery systems; flame retardant; industrial coatings; filtration membranes; antifouling coatings.
Online: 21 April 2021 (11:47:42 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0483.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
Network embedding; multiplex-heterogeneous network; multi-layer network; drug repositioning; graph representation learning
Online: 19 April 2021 (13:21:02 CEST)
REVIEW
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
hyperoxaluria; oxalate; inhibitor; small molecule drug; glycolate oxidase; lactate dehydrogenase; liver selective distribution
Online: 31 December 2020 (08:59:47 CET)
ARTICLE
|
doi:10.20944/preprints202012.0588.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Trazodone; drug design; dissolution; crystal structure; solid-state NMR (SSNMR) spectroscopy; GIPAW calculation
Online: 23 December 2020 (13:42:36 CET)
ARTICLE
|
doi:10.20944/preprints202011.0748.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Keywords: Brimonidine; Laponite; drug delivery; glaucoma; nanomedicine; monitoring; optical coherence tomography; vitreous; intravitreal.
Online: 30 November 2020 (20:25:24 CET)
ARTICLE
|
doi:10.20944/preprints202011.0512.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
antimicrobials; meropenem; generic drug; real-life studies; product surveillance, postmarketing; treatment outcome; pharmacovigilance
Online: 19 November 2020 (13:34:26 CET)
ARTICLE
|
doi:10.20944/preprints202011.0292.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Alzheimer's disease; BACE1; Molecular dynamics; MM/GBSA; Inhibitors; Drug likeness; Ligand efficiency, Kd.
Online: 10 November 2020 (09:10:50 CET)
ARTICLE
|
doi:10.20944/preprints202010.0032.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
Nanomedicine; human ferritin; gastrointestinal tumors; non-camptothecin topoisomerase I inhibitors; drug-delivery; CD71
Online: 2 October 2020 (09:21:53 CEST)
REVIEW
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
apoptosis; antitumor; antimetastasis; anti-angiogenesis; NK-1 receptor; substance P; drug repositioning; Emend
Online: 31 August 2020 (10:11:13 CEST)
ARTICLE
|
doi:10.20944/preprints202007.0424.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
4-Phenylbutyric acid; Colon-targeted drug delivery; Colitis; Prodrug; ER stress; Chemical chaperone
Online: 19 July 2020 (19:15:20 CEST)
REVIEW
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
nucleoid-associated proteins (NAPs); moonlighting proteins; drug target; biofilm; specificity determination; phylogenetic analysis
Online: 7 June 2020 (09:07:56 CEST)
REVIEW
|
doi:10.20944/preprints202005.0342.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
seaweed; metabolites; neuroprotection; Alzheimer’s disease; Parkinson’s disease; ischemic stroke; computer-aided drug discovery
Online: 21 May 2020 (09:49:29 CEST)
REVIEW
|
doi:10.20944/preprints201912.0179.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
globular set; category theory; multidimensional; visual recognition; drug-resistant epilepsy; transcranial magnetic stimulation.
Online: 13 December 2019 (10:37:03 CET)
ARTICLE
|
doi:10.20944/preprints201911.0024.v1
Subject:
Computer Science And Mathematics,
Information Systems
Keywords:
Iranian traditional medicine; Persian medicine; ontology; knowledge-base; Mizaj; temperament; new drug discovery
Online: 3 November 2019 (17:07:50 CET)
ARTICLE
|
doi:10.20944/preprints201908.0253.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
halogen bonding; fluorine; iodine; pentafluorosulfanyl; titration; ab initio calculation; NMR study; drug design
Online: 25 August 2019 (15:41:59 CEST)
ARTICLE
|
doi:10.20944/preprints201803.0144.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
sea anemone; drug discovery; cancer; antiangiogenic; endothelial cells; RGD motif; Kunitz type inhibitor
Online: 19 March 2018 (08:15:38 CET)