Violence against healthcare workers (HCWs) is a widespread, underreported and inadequately prevented problem. Only a few companies have efficient systems for assessing the extent of the phenomenon. In 2005, the health surveillance service of a public health company introduced a system that monitored violence experienced by HCWs by means of three items from the Violent Incident Form (VIF), integrated with departmental in-depth analyses using the participatory ergonomics group technique. In 2005, the annual rate of physical assaults was 8.2%, that of threats 12.0%, while the harassment rate was 19.6%. Over the past twenty years of observation (2005-2024), the percentage of workers who reported experiencing a physical attack in the previous year at their periodic medical examination, has fluctuated between 5.8% and 11.1%, except for the years 2020 and 2021 when, during the COVID-19 pandemic, the rate was 3.9% and 3.2%, respectively. During the same pandemic period, the annual threat rate that ranged from 9.4% to 20.1%, dropped to 7.7%, while the prevalence of harassment, that was between 13.5 and 19.6, fell to 7.2%. HCWs believe that (i) limiting visitor access (ii) a better balance of the demand for services and (iii) a better attitude towards HCWs were the causes of the reduced rate of violence during the pandemic. Recording the violence experienced during health surveillance is an economical, reliable and sustainable risk assessment method.

Climbing is an Olympic discipline in full development and multidisciplinary in nature, in which the influence of body composition and nutritional status on performance has not yet been clarified despite the quest for low weight in anti-gravity disciplines such as climbing. The present study aimed to do a nutritional (3-day dietary diaries) and body composition (ISAK profile) assessment of sport climbing athletes of different genders and sport levels. The mean age of the forty-six Spanish climbers (22 men and 24 women) was 30 years (SD: 9) with 7.66 years of experience (SD: 6.63). The mean somatotype of the athletes was classified as balanced mesomorph. Negative correlations were observed between fat mass variables and climbing level (p<0.01), and positive correlations with forearm circumference (p<0.05). Mean energy availability (EA) was 33.01 kcal-kg FFM1-d1 (SD: 9.02), with 55.6% of athletes in suboptimal EA status and 35.6% in low energy availability (LEA) status. Carbohydrate and protein intakes were below recommendations in 57.8% and 31.1% of athletes, respectively. There were deficient intakes of all micronutrients except phosphorus in males. These findings suggest that climbing athletes are at high risk of developing low energy availability states and concomitant problems. Optimal nutritional monitoring may be advisable in this type of athlete to try to reduce the risk of LEA.

This review paper focuses on the joint toxicity and interaction of carbon-based nanomaterials (CNMs) with co-existing pollutants in aquatic environments. It explores the potential harmful effects of chemical mixtures on living organisms, emphasizing the importance of scientific mod-eling to predict mixed toxic effects. The study involved a systematic literature review to gather information on the joint toxicity and interaction between CNMs and various co-contaminants in aquatic settings. A total of 53 publications were chosen and analyzed, categorizing the studies based on the tested CNMs, types of co-contaminants, and the used species. Common test models included fish and microalgae, with zebrafish being the most studied species. The review under-scores the necessity of conducting mixture toxicity testing to assess whether the combined effects of CNMs and co-existing pollutants are additive, synergistic, or antagonistic. The development of in silico models based on the solid foundation of research data represents the best opportunity for joint toxicity prediction, eliminating the need in a great quantity of experimental studies.

The Automatic Dependent Surveillance-Broadcast (ADS-B) protocol stands as a cornerstone in modern aviation surveillance and Aircraft Traffic Control systems, integral to the NextGen project initiated by the US Department of Federal Aviation Administration (FAA) in 2005. ADS-B utilizes data links to autonomously broadcast Aircraft navigational and identification information to augment air transportation system capacity and safety. However, concerns regarding the protocol's security persist, particularly as its adoption expands. The unencrypted nature of transmitted aircraft data and the absence of robust authentication mechanisms render the protocol susceptible to exploitation by malicious actors. In this study, we comprehensively reviewed existing research in the field, identifying a crucial gap necessitating a holistic survey. Prior surveys have predominantly focused on specific aspects, such as vulnerabilities, attacks, or critiques of existing solutions. Our survey addresses this gap by thoroughly exploring the aviation system, providing readers with a nuanced understanding of ADS-B security. Utilizing a detailed SWOT analysis diagram, our paper delves into the vulnerabilities inherent in the ADS-B protocol outlines potential threats and scrutinizes various attack scenarios. We systematically categorize and analyze existing security solutions, considering cost-effectiveness, scalability, implementation complexity, and coverage against diverse attack vectors. Furthermore, we critically evaluate these solutions, elucidate ADS-B security requirements, discuss current challenges, and propose future research directions. This survey serves as a comprehensive resource for researchers and practitioners alike, shedding light on the multifaceted landscape of ADS-B security and paving the way for enhanced aviation system resilience in the face of evolving cybersecurity threats.

Earthquake-triggered landslides represent a significant seismic-related disaster, posing threats to both the lives and properties of individuals in affected areas. Furthermore, they can result in road and river blockages, as well as other secondary disasters, significantly impacting post-earthquake rescue efforts. Efficient and accurate rapid assessment of high-risk landslide zones carries important implications for decision-making in disaster response and for mitigating potential secondary disasters. This study uses the high-intensity Zone VII to IX of the 5 September 2022 Luding Ms6.8 earthquake as a case study. The "difference method" and the "cumulative displacement method," based on the simple Newmark model, are employed to assess earthquake-triggered landslides. The evaluation results from both methods demonstrate that the areas posing an ex-tremely high risk of earthquake-triggered landslides are predominantly situated on the western side of the Xianshuihe Fault. Actual landslide data verification shows that both models have high predictive accuracy, with the difference method model slightly outper-forming the cumulative displacement method model. Moreover, the study recommends determining threshold values for each landslide hazard interval with significant physical meaning using past strong earthquake data as soon as possible when utilizing the difference method to assess the risk of earthquake-triggered landslides.

This qualitative study explores the multifaceted strategies organizations employ to build resilient supply chains through effective procurement risk management. Conducted over a six-month period in 2024, the research involved semi-structured interviews with 25 industry professionals from sectors including manufacturing, retail, healthcare, and technology, alongside document analysis and case studies. The study identifies four key themes: risk identification and assessment, supplier relationship management, digitalization in risk management, and strategic resilience practices. The findings reveal that organizations face diverse risks, including supplier, supply market, and external environmental risks, necessitating comprehensive risk assessment methodologies. Supplier relationship management emerges as a critical factor in mitigating risks, with practices such as regular audits, collaborative risk management, long-term partnerships, and supplier diversification being crucial. The adoption of digital technologies like predictive analytics, blockchain, advanced analytics, and artificial intelligence enhances risk management capabilities, providing data-driven insights and fostering transparency. Strategic resilience practices, including inventory buffering, flexible sourcing, redundancy, and scenario planning, are essential for maintaining supply chain continuity amidst disruptions. The study underscores the importance of an integrated and proactive approach to procurement risk management that leverages robust assessment, strong supplier relationships, digital tools, and strategic planning. These findings contribute to a deeper understanding of how organizations can effectively manage procurement risks and build resilient supply chains in a dynamic global environment. The insights offer valuable guidance for procurement professionals and organizational leaders in developing resilient and adaptable supply chain strategies to navigate the complexities of today's market.

Atherosclerotic cardiovascular disease, a leading cause of morbidity and mortality worldwide, is a chronic inflammatory disease, linked to a state oxidative stress, with several well-identified culprits, of which low-density-lipoprotein cholesterol (LDL-C) and lipoprotein(a). No specific treatment is currently available to lower lipoprotein(a). It is, therefore, of paramount importance to identify nutritional factors that could lower lipoprotein(a). Growing evidence shows that although reducing saturated fatty acid (SFA) intake decreases LDL-C, it could increase lipoprotein(a). Optimal dietary recommendations may therefore differ depending on an in-dividual’s baseline lipoprotein(a) and LDL-C levels. Assessing the diet-induced true LDL-C response and net balance of these two atherogenic entities is difficult because LDL-C measurement is confounded by lipoprotein(a) cholesterol content. We have estimated, for the first time, the net atherogenic result of diet-induced variations of both LDL-C and lipoprotein(a), thanks to our new concept of LDLapoB risk equivalent=apoB+lp(a)x5 (in nmol/L). This is illustrated, via the rare case of a physician with very high lipoprotein(a) and hypobetalipoproteinemia. She experiences twice a considerable lipoprotein(a) increase (+32%, + 28mg/dL, + 67nmol/L) and higher LDLapoB risk equivalent (138mg/dL versus 123mg/dL) on a mediterranean diet, low in SFA. A reasonable SFA intake, despite causing marginal LDL-C increase, may be advisable in patients with high lipoprotein(a) who need personalized dietary recommendations.

In response to the escalating global waste production rate, sustainable waste management be-comes indispensable. In parallel, the transformation of energy system is vital in order to ensure affordable, decentralized, and sustainable energy for the global community, based on economic, environmental, and social criteria. Waste-to-Energy (WtE) is an effective option in order to put a stepping stone to address both issues provided that multiple views and criteria are considered. This paper puts forward a generic methodological framework to holistically assess WtE technologies based on the PROMETHEE approach. In addition to environmental, economic, and social aspects, demonstration of applicability of the proposed methodology is realized at national level the case of Greece. Anaerobic Digestion seems to be the most preferable choice, recognized for its cost-effectiveness and lower environmental burden to other WtE technologies (i.e. gasification, pyrolysis, incineration). Insightful expert opinions and public preference are of paramount importance to the adopted approach, revealing technology-specific concerns and preferences. In addition, the material presented underscores a crucial gap in Life Cycle Assessment studies for large-scale WtE, emphasizing the need for future scientific attention and exploration. Public consensus indicates a positive overall attitude towards waste valorization in the context of energy production.

The prolonged static sitting at the workplace is considered as one of the main risks for development of musculoskeletal disorders (MSDs) and adverse health effects. Factors such as poor posture and extended sitting are perceived to be a reason for conditions such as lumbar hyperlordosis and lower back pain (LBP), even though the scientific explanation of this relationship is still unclear and raises disputes in the scientific community. This publication proposes the low back pain assessment (LBPA) dataset collected through experiment with 100 participants and consisting of photogrammetric images with intentionally placed body markers, calculated postural angles and tags correct and incorrect posture assessed by habilitated rehabilitator, as well as questionnaire-based self-reports regarding the occurrence of LBP and similar symptoms among the participants. Machine learning models trained with this data are employed for recognizing incorrect body postures. Two scenarios have been elaborated for modeling purposes: scenario 1, based on natural body posture tagged as correct and incorrect, and scenario 2, based on incorrect body postures, corrected additionally by the rehabilitator. The achieved accuracies of respectively 75.3% and 85% for both scenarios reveal the potential for future research in enhancing awareness and actively managing posture-related issues that elevate the likelihood of developing lower back pain symptoms.

This study addresses the pressing need for flood extent and exposure information in data-scarce and vulnerable regions, with a specific focus on West Africa, particularly Senegal. Leveraging the Google Earth Engine (GEE) platform and integrating data from Sentinel-1 SAR, Global Surface Water, HydroSHEDS, Global Human Layer Settlement, and MODIS Land Cover, our primary ob-jective is to delineate flood extents and compare them with centennial flood-prone areas, offering a comprehensive assessment of exposure during the period from July to October 2022 across Sen-egal's 14 regions. The findings underscore a total inundation area of 2 951 square kilometers, impacting 297 142 people, 175 square kilometers of urban and 16 square kilometers of crops. Notably, August wit-nessed the largest flooded areas, reaching 780 square kilometers, constituting 0.40% of the coun-try's surface. Subsequent regions, including Saint-Louis, Ziguinchor, Fatick, and Matam, experi-enced varying extents of flooding, with August data showing a 1.34% overall overlap compared to centennial flood-prone areas derived from hydrological and hydraulic modeling. This low per-centage reveals the distinct purposes and natures of the two approaches (remote sensing and modeling), as well as their complementarity. Turning to flood exposure, August emerges as the most critical month, affecting 76 595 people (0.43% of the total population). Dakar, Diourbel, Thiès, and Saint-Louis regions bore substantial impacts, affecting 100 707, 57 648, 31 579, and 26 581 people, respectively. These findings emphasize the imperative for comprehensive disaster preparedness and mitigation efforts. The study provides a crucial national-scale perspective to guide Senegal's authorities in formulating effective flood management, intervention, and adaptation strategies.

Aileen Oeberst and Roland Imhoff’s remarkable paper (Perspectives on Psychological Science 2023; 18: 1464-87). should be compulsory reading for all intelligence analysts. It offers a tantalisingly parsimonious explanation comprising the combination of strongly held prior 'beliefs' coupled with subsequent 'belief-consistent information processing' (akin to confirmation bias) - an explanation that simplifies understanding of a vast array of cognitive biases, and thereby suggests that all of these might be attenuated through the application of accessible analytical and assessment practices. What this means for intelligence analysis will be determined by the explicit and implicit 'beliefs' (or, more generally, ‘value[s]’) attributed to any evidence available, and any insight generated, to reduce decision-makers’ uncertainty and unsubstantiated certainty, and thereby offer them future advantage. Analysts are well aware that different sources of evidence (whether empirical, theoretical or entirely speculative) can assign different types and amounts of ‘prior value’ to the information available for intelligence analysis and assessment. Acknowledging such value as a potential driver of subsequent confirmation bias should help analysts guard against any inherent tendency to preference evidence solely on the basis that this was initially considered most ‘valuable’. Instead they should subject all evidence and all insight – regardless of perceived ‘value’ – to a consistent battery of systematic, rigorous and robust evaluation.

Natural Fibre Composites (NFC) are eco-friendly, sustainable alternatives to synthetic polymers. However, some intrinsic natural fillers´ properties hinder their widespread implementation as re-inforcement in polymeric matrices and require further investigation. In the scope of this study, the thermal, rheologic, mechanical (tension and flexural modes), morphological properties, water ab-sorption and dimensional stability of the NF polypropylene (PP) based injection moulded compo-sites with the rice husk (rh) and olive pits (op) of 20 wt% and 30% wt%, were investigated. The results suggest that the higher content of the rice husk and olive pits led to a similar reduction of the Melt Flow Index (MFI), independent of the additive type compared to virgin polypropylene (PPv). The melting and crystallization temperatures of the PPrh and PPop composites did not change with statistical significance. The composites are stiffer than the PP matrix by up to 49% and possess higher mechanical strength in what concerns the tension mode at the expense of de-creased ductility. PPrh and PPop have superior flexural modulus in the bending mode, while the flexural strength improvement was accomplished for the PP30%rh. The dimensional stability of the composites was improved as the linear shrinkage in the flow direction was decreased by 49% for PPrh and 30% for PPop, positively correlating with an increase in the filler content and stiff-ness. PPop was less susceptible to water sorption than PPrh due to fibres' composition and larger surface-to-area volume ratios.

Current research on smart cities is primarily focused on the area of applicability of information and communication technologies. However, in the context of a multidisciplinary approach, it is also necessary to pay attention to the resilience and converged security of individual infrastructures. Converged security represents a particular security type based on a selected spectrum of certain convergent security types of, assuming the creation of a complementary whole. Considering the outputs of the analysis of security breaches manifestations, this kind of security makes it possible to detect emerging security breaches earlier (still in the symptom stage), thus providing a more efficient and targeted solution suitable for building smart city infrastructure. In its essence, the article refers the practical application of the theoretical principles of converged security presented in the publication to a functional sample, deployed and tested in practical conditions of selected smart city infrastructure protection and resilience. Considering the nature of the practical application, the convergence of a wider spectrum of smart security alarm systems in the context of resilience assessment is defined. In the beginning, the general principles of security/ safety and the need for their convergence are presented. In this context, the mathematical model called Converged Resilience Assessment method is presented for better understanding. Subsequently, PSIM and SIEM systems are described as a technological concept that can be used for resilience assessment. The most beneficial part is the structural, process and functional description of the Converged Security and Information Management System (CSIM) using the concept of smart security alarm systems converged security.

The Internet of Things (IoT) continues to grow at a rapid pace, becoming integrated into the daily operations of individuals and organisations. IoT systems automate crucial services within daily life that users may rely on, which makes the assurance of security towards entities such as devices and information even more significant. In this paper, we present a comprehensive survey of papers that model cyber risk management processes within the context of IoT, and provide recommendations for further work. Using 39 collected papers, we studied IoT cyber risk management frameworks against four research questions that delve into cyber risk management concepts and human-orientated vulnerabilities. The importance of this work being human-driven is to better understand how individuals can affect risk and the ways that humans can be impacted by attacks within different IoT domains. Through the analysis, we identified open areas for future research and ideas that researchers should consider.

3D measurement is a high-throughput method that can record a large amount of information. In this study, we have developed new methods that could be used for morphological analysis of plants from the information contained in 3D data. Specifically, we investigated characteristics that can be measured by scale (dimension) and/or visual assessment by humans. The characteristics that can be measured on a scale-related dimension were tested based on the bounding box, convex hull, column solid, and voxel. Furthermore, for characteristics that can be evaluated by visual assessment, we propose a new method using normal vectors and local curvature (LC) data. For these examinations, we used our highly accurate all-around 3D plant modelling system. The correlation coefficients between manual measurements and the scale-related methods were all above 0.9. In particular, the differences in LC calculated from the normal vector data allowed us to visualize and quantify the concavity and convexity of leaves. Furthermore, we also found a difference in the time point at which leaf blistering began to develop among the cultivars. The precise 3D model made it possible to perform quantitative measurements of lettuce size and morphological characteristics. In addition, the newly proposed LC-based analysis method made it possible to quantify the characteristics that rely on visual assessment.

Geriatric decisional capacity assessment is a complex medico-legal activity that evaluates normal subjects involved in specific civil matter like wealth transfer, access to treatment or voluntary hospitalization. Our objective was to evaluate how geriatric extrajudicial capacity exams impacted a general psychiatric unit over a decade. We also assessed the value of a surrogate biomarker (neutrophils to lymphocyte ratio) as a screening factor in the capacity assessment process. 72 cases were assessed in one psychiatric unit over a decade (2009-2018). As population was fast ageing, the total number of capacity exams per year doubled in time. None of the subjects had an active diagnostic of severe cognitive impairment or active psychiatric disease. The percentage of subjects receiving an “absence of capacity” conclusion remained constant over time (approx. 20% of all cases). 81% of the subjects within this subgroup had a clinical diagnostic of mild cognitive impairment compared to 46% in the “presence of capacity” subgroup (p&lt;0.001). The surrogate biomarker neutrophils to lymphocyte ratio was significantly higher in the “absence of capacity” subgroup, mainly related to a cognitive impairment diagnostic. The ratio has to be validated by larger studies before to be included in the capacity assessment process as an early screening tool.

In its 8th Malaysia Plan (MP*), the Malaysian government has given nanotechnology development a high priority and has been made a Strategic Research (SR) programme. Consequently, an exhaustive and long-term approach is essential. Additionally, specific laws are required to provide an optimal health and safety environment for workers. Consequently, the current study intends to assist Malaysian policymakers in promoting improved safety, risk assessment, and management for nanotechnology workplaces, as well as drafting a comprehensive policy for the recently released DOSH guideline in 2018. Utilizing a unique methodology, this study evaluated the assessment and management of nanotechnology health and safety risks in Malaysia using the international risk governance council (IRGC) framework. In addition to document analysis, n = 20 semi-structured interviews were conducted with representatives of several nanotechnology platforms to collect data that was then analyzed thematically. The research evaluated current workplace safety regulations and laws. Consequently, we propose a future dynamic strategy for Malaysian nanotechnology with more favourable upgrades supported by increased concentrations in the following areas: I policy creation, ii) comprehensive management system, iii) knowledge transfer, and iv) infrastructure management. In addition, the findings highlight the need of cross-sectional communication in bridging existing gaps. This study laid the groundwork for a more systematic and comprehensive health and safety strategy.

We describe a recently developed approach to quantify welfare loss in animals, the Cumulative Pain metric. It combines the two most relevant dimensions of negative affective experiences: intensity and duration. The metric enables estimating the time individuals spend in negative affective states of a physical or psychological nature (operationally referred to simply as ‘pain’) of different intensities as the result of one or more challenges (e.g., diseases, injuries, deprivations). A new notation protocol (the Pain-Track) is used in which the duration of the experience is represented along the horizontal axis and intensity is represented by four categories in the vertical axis. Pain experiences are partitioned into temporal segments, where hypotheses for the experienced duration and intensity are proposed based on existing welfare indicators (e.g., neurophysiological, behavioral, anatomical, evolutionary). This structure forces transparency about assumptions and uncertainties, highlights knowledge gaps, and enables estimates to be continuously adjusted. Because the Cumulative Pain metric is based on parameters with a broadly common biological meaning, it provides the much needed interoperability among assessments of animal welfare. It enables comparing the impact of practices and living conditions, policies and interventions, and the calculation of welfare footprints of animal-sourced products using a universal measurement unit.

Objective: Radiomics and deep transfer learning are two popular technologies used to develop computer-aided detection and diadnosis (CAD) schemes of medical images. This study aims to investigate and compare advantages and potential limitations of applying these two technologies in developing CAD schemes. Methods: A relatively large and diverse retrospective dataset including 3,000 digital mammograms is assembled in which 1,496 images depict malignant lesions and 1,054 images depict benign lesions. Two CAD schemes are developed to classify breast lesions. The first scheme is developed using four steps namely, applying an adaptive multi-layer topographic region growing algorithm to segment lesions, computing initial radiomics features, applying a principal component algorithm to generate an optimal feature vector, and building a support vector machine classifier. The second CAD scheme is built based a pre-trained residual net architecture (ResNet50) as a transfer learning model to classify breast lesions. Both CAD schemes are trained and tested using a 10-fold cross-validation method. Several score fusion methods are also investigated to classify breast lesions. CAD classification performance is evaluated by the area under ROC curve (AUC). Results: ResNet50 model-based CAD scheme yields AUC = 0.85±0.02, which is significantly higher than radiomics feature-based CAD scheme with AUC = 0.77±0.02 (p < 0.01). Additionally, fusion of classification scores generated by two CAD schemes does not further improve classification performance. Conclusion: This study indicates that using deep transfer learning is more efficient to develop CAD schemes and enables to yield higher lesion classification performance than CAD schemes developed using radiomics-based technology.

The Short-Term Assessment of Risk and Treatability (START) is deemed the most appropriate instrument for assessing violence risks and management because of its balanced approach between dynamic risk and protective factors. Although several facets of reliability and predictive validity of this tool were strong, its inter-rater reliability, construct validity, and implementation in Asian population were under-investigated. The objective of this research was to examine the inter-rater reliability and construct validity of the START: Thai version within forensic psychiatric inpatients. The participants consisted of 118 forensic psychiatric inpatients hospitalized at Galya Rajanagarindra Institute in Thailand. Trained mental health professionals (i.e., psychiatrists, forensic nurses, clinical psychologists, social workers, and occupational therapists) assessed each participant across twenty domains of the Thai START. The inter-rater reliability was examined using the intraclass correlation coefficient and a confirmatory factor analysis for ordinal data was used to test the construct validity of the scale. The main finding showed a good-to-excellent inter-rater reliability and supported two relational constructs (i.e., strength vs vulnerability subscales) of the Thai START. The Thai START is a promising tool for using in Thai forensic psychiatric setting but some items were not significant in contributing to the scale. This study also provides the guideline for implementing the tool in non-Western forensic psychiatric populations.

Anemia and thyroid disorders are global health issues that affect all ages but are more apparent in women. In this case, some serological components responsible for IDA and TSH disorders in women have been found actively regulated through a complex steroidal-calcitriol mediated pathway. This research has been investigated the correlation between Calcitriol and the serological components responsible for IDA and TSH disorders in childbearing and non-child-bearing women of different health conditions. Experimental sampling from 452 women suffering from both IDA and TSH disorders were taken, aged between 0 and 70 years. Serological parameters, such as iron, total iron-binding capacity and ferritin, were assessed for IDA profiling, whereas thyroid-stimulating hormone and free thyroxin were for TSH profiling based on the individual’s serum calcitriol status. The resulted serological data were interpreted using sophisticated computer programming language and algorithms for quantitative biochemical analysis. The study resulted in a significant correlation between FT4 and Calcitriol (P<0.0001) for all age groups. TSH also showed strong interactions with the fluctuation of calcitriol level (P<0.0001), except for the children aged below 10 years (P<0.063). The iron, TIBC, TSH, and FT4 showed phenomenal regulation with the steroidal-calcitriol concentration for congenital patients. Unlike the others, ferritin has a substantial connection with Calcitriol (P<0.0064) fluctuation in the serum. To ratify, the concentrations of TSH, FT4, iron, TIBC, and ferritin were found to be significantly interconnected in terms of serum calcitriol level in women suffering from IDA and TSH disorders simultaneously. To understand the accuracy and efficacy of the Calcitriol in IDA and TSH disorders, some other inflammatory markers and parathyroid hormone analysis are need in future studies, besides a large number of samples.

: Chemical accidents can occur anywhere. The need for chemical management in Korea was realized following the 2012 Gumi hydrofluoric acid accident in 2012. The Chemicals Control Act was enacted in 2015. This system evaluates the risks (high, medium, low) and consequent safety management at all plants that handle hazardous chemical substances. However, the system was criticized as excessive when most plants were designated high-risk without considering their size. Thus, laboratories and hospitals handling very small quantities were subject to regulation. Accordingly, in 2021 Korea revised the system to include off-site consequence analyses and a Korean-style risk analysis. Plants handling very small quantities, such as laboratories and hospitals, were exempt from regulation. In this study, plating and paint manufacturing companies, which were classified as high-risk in the previous system, even though they were medium-size business plants, were re-evaluated as low-risk plants. In the Korean-style risk analysis, it is possible to see at a glance what is lacking in the plants, such as cooperation between local residents and local governments and the construction of safety facilities according to the type of accident scenario. The revised system is a reasonable regulation for medium business plants.

Rail transit tunnels span long distances, are large-scale structures and pass through complicated geological conditions; thus, the risk of uneven settlement cannot be ignored. To address this issue, a method for diagnosing the uneven settlement of regional railway tunnels based on the spatial correlation of high-density strain measurement points is proposed in this study. First, distributed optical fiber sensing technology is implemented to obtain a massive amount of strain data from densely distributed measurement points along regional railway tunnels, and a method for determining the intervals of strain measurement points with strong spatial correlations is proposed based on a support vector machine. Second, combined with the statistical analysis of the influence range of the uneven settlement of a tunnel, an algorithm for diagnosing the uneven settlement of regional railway tunnels based on the spatial correlation of high-density strain measurement points is proposed; this approach realizes the accurate identification of the uneven settlement area of long-distance urban railway tunnels. Finally, the effectiveness of the proposed method is verified by numerical simulation and actual tunnel data.

Zimbabwe has ambitious and laudable GHG mitigation targets. Compared to a coal based future emissions reductions by 33% per capita by 2030 are targeted, by implementing a set of identified nationally determined contributions (NDCs). If historical climate conditions continue, it can do this at low or negative cost. However, anticipated conditions may not continue, and of the planned emissions reductions in the NDCs, 88% would come from the expansion of hydropower, which is driven by rainfall. If climate change causes the extreme droughts witnessed in recent years to become more frequent, embarking on Zimbabwe’s NDC future (underpinned by its official system development plan) may be expensive and further cripple the economy. Note that the economy is already being strangled by constrained power supplies due to unusually dry conditions in the Zambezi river basin. If the NDC Future is pursued, but the climate becomes drier, proactive efforts might be made to overcome the power shortages. However, this may result in a rapid ramp up of greenhouse gas emissions if the country turns to coal to reinforce its system and increase its resilience against hydropower vulnerability and the costs that would otherwise ensue. If the country were to keep its NDC investments and supplement them with more aggressive deployment of clean adaptation options, strongly positive outcomes appear possible. Specifically, this would require increased deployment of renewable energy technologies, a restructured power market, and deep increases in energy efficiency investments. In so doing, the country would not only exceed its NDC targets, but also reduce costs in a manner that is climate resilient. This would not remove the country's need for hydropower and some level of coal reliance. However, it will introduce requirements to ensure flexibility in both hydropower and coal power production. For hydropower, power stations will need to provide and be recompensed for providing ‘balancing services’, that is, storing water and producing electricity when the wind is not blowing, nor sun shining. In order to ensure continuous output from mines, it may require intelligent stockpiling combined with dynamic forecasting. This would apply not only to production in Zimbabwe, but potentially for neighboring countries. Doing so would allow predictable mining activities, but allow electricity systems to absorb low cost, low carbon hydropower at high rainfall periods. To make the NDCs resilient via clean adaptation, strong institutional restructuring is required. However, internalizing those costs and moving to advanced market structures and business cases may strain the capacity of current institutions.

The transport sector in Germany causes one-quarter of energy-related greenhouse gas emissions. One potential solution to reduce these emissions is the use of battery electric vehicles. Although a number of life cycle assessments have been conducted for these vehicles, the influence of a transport system wide transition has not been researched sufficiently. Therefore, we developed a method which combines life cycle assessment with an agent-based transport simulation and synthetic electric, diesel and gasoline powered vehicle models. We use the transport simulation to obtain the number of vehicles, their lifetime mileage and road-specific consumption. Subsequently we analyze the product systems’ vehicle production, use phase and End-of-Life. The results are scaled depending on the covered distance, the vehicle weight and the consumption for the whole life cycle. The results indicate that the sole transition of drive trains is insufficient to significantly lower the greenhouse gas emissions. However, sensitivity analyses demonstrate that there is a considerable potential to reduce greenhouse gas emissions with higher shares of renewable energies, a different vehicle distribution and a higher lifetime mileage. The method facilitates the assessment of the ecological impacts of the complete car based transportation in urban agglomerations and is able to analyze different transport sectors.

Unrecorded alcohol comprises all types of alcohol that is not registered in the jurisdiction where it is consumed. In some countries in Central and Eastern parts of Europe as well as the Balkan, the major amount of unrecorded alcohol consumption may derive from homeproduction of fruit spirits. Some studies found a high prevalence of lead and cadmium in such spirits. This article provides a quantitative comparative risk assessment using the margin of exposure (MOE) methodology for lead and cadmium, compared to ethanol, for unrecorded fruit spirits. For average concentration levels, the lowest MOE (0.8) was calculated for ethanol (alcohol itself). For lead, the MOE was 13 for moderate daily drinking and 0.9 for the worst case. For cadmium, the MOE was 1982 for moderate daily drinking and 113 for the worst case. The results of this study are consistent with previous comparative risk assessments that ethanol itself comprises by far the highest risk of all compounds in alcoholic beverages. Regarding the metal contaminants, the risk of cadmium appears negligible, however, lead may pose an additional health risk in heavy drinking circumstances. Strategies to avoid metal contamination in settings of artisanal homeproduction of spirits need to be developed.

Talking about sustainable development refers mainly to the environmental sphere, but the concept is much broader and also takes into account the social and economic conditions. The concept of sustainability, in this sense, is linked to the compatibility between the development of economic activities, the related social phenomena, and the protection of the environment. Therefore, the ability to balance social, economic and environmental sustainability is the very meaning of the concept of sustainable development. Firms that choose to develop policies and strategies to enhance and pursue sustainable development in the medium to long term have the burden of having to quantitatively document the improvements in production processes with the aim of sustainable development. As a result, one of the biggest challenges for European industry is to introduce sustainability principles into business models leading to competitive advantage. This is particularly important in raw material and energy intensive manufacturing sectors such as the ceramic industry. The present state of knowledge lacks a comprehensive operational tool for industry to support decision-making processes geared towards sustainability. In the ceramic sector, the economic and social dimensions of the product and processes have not yet been given sufficient importance. Moreover, the traditional research on industrial districts lacks an analysis of the relations between firms and the territory with a view to sustainability. Finally, the attention of scholars in the field of economic and social sustainability, has not yet turned to the analysis of the Sassuolo district. Therefore, in this paper we introduce the Life Cycle Sustainability Assessment (LCSA), as a method that can be a suitable tool to fill this gap, because through a mathematical model it is possible to obtain the information useful for decision makers to integrate the principles of sustainability both at the microeconomic level in enterprises, and at the meso-economic level for the definition of economic policies and territorial governance. Environmental and socio-economic analysis was performed from the extraction of raw materials to the packaging of the product on different product categories manufactured by the Italian ceramic industries of the Sassuolo district (northern Italy). For the first time the LCSA model, usually applied to unitary processes, is extended to the economic and industrial activities of the entire district, extending the prospect of investigation from the enterprise and its value chain to the integrated network of district enterprises.

Climate change remains a pressing global issue affecting sectors including agriculture and forest resources in countries such as Uganda. This research focused on exploring the viewpoints of youth in Uganda concerning adapting to climate change and their interest in getting involved in agroforestry transition. By conducting a survey involving 1138 participants from the youth demographic group aimed to gather information about their level of hopefulness towards climate adaptation efforts and how they perceive the impact of farming practices and deforestation. Furthermore, the study aimed to evaluate youth willingness to participate in agroforestry (WTP) initiatives. The study used descriptive statistics as well as Ordinary Least Squares (OLS) to analyze the collected data. We found that most participants are climate change hopeful about adapting to climate change (89%). This positive and highly significant outlook is closely related to their willingness to participate in agroforestry adaptation efforts (0.0001). Moreover, a high percentage of participants (92%) acknowledged how farming practices such as cultivation and livestock rearing can degrade land significantly. Whereas Gender, Age and Employment were found to be highly and positively significant regarding youth’s WTP in agroforestry (0.0001), Income was not. Incorporating indigenous practices and encouraging meaningful involvement from policymakers can empower the youth and strengthen community-led initiatives to address environmental decline effectively. This research highlights the capacity of youth engagement in steering successful climate resilience measures via agroforestry practices in Uganda.

Children account for a significant proportion of the world's population and are a particularly vulnerable subpopulation regarding environmental factors. In a scoping review of a total of 3130 articles compiled from relevant medical literature, including 107 publications, we provide an empirical overview of the literature on masks in connection with children, particularly with regard to its' expected effects on viruses during the pandemic 2020-2023 versus scientific reality and evidence, including the side effects. While masks lack ecological validity from a strictly empirical point of view (transferability of experimental results from laboratories and modelling to the real world, e.g. to situations or environments typical of everyday life) and high-quality studies are showing little evidence of their effectiveness in real-world scenarios, whereas the side effects appear to be clear. An individual risk-benefit analysis is necessary and also a consideration of the situations, in which the use of masks in children could be justified. This review including the literature found and analysed will be able to help when making decisions in this regard.

This qualitative study investigates the management of supplier risks in e-commerce through relationship management strategies, focusing on trust-building, communication practices, digital technology integration, risk assessment methodologies, challenges, innovation initiatives, and ethical considerations. The research aims to provide nuanced insights into how e-commerce companies navigate the complexities of global supply chains to mitigate operational, financial, and reputational risks associated with supplier relationships. Through semi-structured interviews with 20 key stakeholders in the e-commerce sector, data were collected and analyzed using thematic analysis. The findings underscored the foundational role of trust in establishing resilient supplier relationships, facilitated by transparent communication, consistent performance evaluation, and mutual respect for contractual obligations. Effective communication practices, supported by digital platforms and technologies such as AI, blockchain, IoT, and cloud computing, enhanced operational transparency and decision-making capabilities across supply chains. The study identified diverse approaches to risk assessment, from qualitative evaluations to quantitative models utilizing predictive analytics and scenario planning. However, participants highlighted challenges including geopolitical uncertainties, trade disruptions, regulatory changes, and cultural barriers, necessitating adaptive strategies and diversified sourcing options. Innovation initiatives such as joint product development and technology adoption were crucial in enhancing supply chain agility and competitive advantage. Ethical considerations emerged as a critical aspect, influencing supplier selection criteria, CSR initiatives, environmental sustainability practices, and labor standards compliance. Integrating ethical guidelines into supplier contracts reinforced corporate values and enhanced brand reputation. Overall, this study contributes practical implications for e-commerce practitioners seeking to enhance supply chain resilience, mitigate supplier risks, and sustain competitive advantage in a dynamic global marketplace.

Pollution, urbanization and technological advancements have posed stress on the ecosystem and its matrices. Globally, pollutants are observed in all compartments of ecological communities which affect the integrity of the atmosphere, hydrosphere, lithosphere and biosphere. Xenobiotics bioaccumulate and biomagnify across trophic levels or webs. Heavy metals have been implicated in impacts towards biodiversity and environmental declination. In Nigeria, wastes issues are a cause of concern and landfilling or are waste disposal approaches that cause deleterious effects such as depauperation of diversity and species decline, prompting the non-invasive ecotoxicological hazard assessments. Feathers were used to assess concentration levels of 13 metals (Fe, Mn, Zn, Cu, Co, Cr, Cd, Pb, Ni, Al, B, Se and Hg) using fast atomic absorption spectrophotometer (FAAS), one-way ANOVA was used in comparing variations in mean concentrations across trophic levels, diversity indices and point count methods were used to estimate diversity and abundance. Four avian species were assessed Hirundo aethiopica (insectivore), Streptoptelia senegalensis (granivore), Turdus pelios (omnivore), and Anthus leucophrys. (insectivore). Observed concentrations of important metals like iron were high with the insectivores having the highest concentrations of iron (2.6985 ± 0.1975 ppm) and granivores having the lowest (2.0100 ± 0.3172 ppm). The insectivores had the highest concentrations for cadmium, cobalt and chromium (0.0005 ± 0.0005ppm), nickel (at 00.0012 ± 0.0017 ppm) and least was observed in the granivores (0.0003 ± 0.0006 ppm). Selenium concentrations were quite high in insectivores (0.0775 ± 0.0035 ppm) and lowest in granivores (0.0433 ± 0.0015 ppm) likewise mercury for insectivores (0.0280 ± 0.0010 ppm) and granivores (0.0213 ± 0.0015 ppm). From the study, it is apparent that landfills are sources of pollution and poor management of wastes can affect biota (causing effects such as asymmetry and bioaccumulation) and ecosystem balance. The observation of heavy metals in the feathers serve as good sentinels due to their trophic levels and could be signs for what could be yet to occur. The heavy metal concentrations were significantly different at p < 0.05.

It remains unclear in the literature what is the cause of the so-called alkali-carbonate reaction (ACR) damage to concrete yet, a consensus is reached when considering dedolimitization as non-expansive. However, expansion and cracks as distress features are often attributed to alkali-silica reaction (ASR) when evidence of a reactive mineral is found in the aggregate. Evidently, different types of aggregates may produce different types and degrees of damage. Therefore, this work aims to assess the damage to concrete generated and propagated by the so-called ACR susceptible reactive Kingston coarse aggregate through mechanical testing (i.e., direct shear test), microscopy (the damage rating index – DRI), and other techniques. Distinct induced expansion levels (i.e., 0%, 0.05%, 0.12%, and 0.20%) were selected to compare the distress caused by ACR to concrete affected by ASR. Result show that the behaviour of ACR, namely as captured through the DRI, is inconsistent with that of ASR thus attesting to ACR being a distinct distress mechanism.

The sustainability of cities often changes as rapid urban developments and population growth affect the carrying capacity. Understanding the dynamics of carrying capacity then becomes crucial for tourist-oriented cities. This study focused on Baguio City, the "Summer Capital of the Philippines," attracting large crowds on holidays and actively promoting various events on non-holidays, thereby having temporal context variations classified as regular days, days with events, and holidays. Using the enhanced urban carrying capacity load number (EUCCLN) model, load number (LN) changes for different temporal contexts are calculated based on spatial indicators grouped into air, traffic, economy, and waste. The city experiences the worst pressures on air quality during holidays with $99.23\%$ districts under very high to critical levels followed by regular and days with events. However, the total LN is balanced by favorable economic conditions with only $9.23\%$ at critical. EUCCLN effectively pinpoints areas experiencing critical states at any time, advocating targeted government monitoring. We demonstrate that Night Time Light, for places with no economic data available, can be used as a proxy to highlight areas requiring improved urban vibrancy. This work suggests that EUCCLN monitoring urban pressures can easily be expanded to nowcasting with real-time data.

Life Cycle Assessment (LCA) is a technique developed to measure possible environmental impacts during the manufacture and use of a given product or service. Additive Manufacturing (AM) has proven to be suitable in several industries, especially wire and arc additive manufacturing (WAAM), offering many advantages such as delivery time and reduction in terms of material waste, energy consumption and equivalent CO₂ emissions (CO₂e). This study aimed to develop a methodology to evaluate environmental indicators during the life cycle assessment, from gate-to-gate, in the production of two low-alloy carbon steel metal parts (flanges) using ER-90 wire and allowed identifying the main stages that most influence environmental indicators. The total energy consumption in the production of flanges 1 and 2 were, respectively, 10,239.0 MJ, 12,754.0 MJ and the total carbon footprint, respectively, 714.1 kgCO₂e kg^-1 and 749.3 kgCO₂e kg^-1.

Adequate public spaces and urban green areas are key criteria for urban development and infrastructure implementation of healthy cities. Latterly, there has been an increasing number of research methods using artificial intelligence (AI) to monitor, quantify, and control the state of these spaces with an aim towards pioneering research in Urban Studies. However, in informal areas, open-data access tends to lack adequate and updated information, making it difficult to use AI methods. Hence, we propose a methodology for restricted open data collection and preparation for future use in machine learning or spatial data science models for similar areas. To that extent, we examine two peripheral and low-income neighborhoods in Quito, Ecuador, La Bota and Toctiuco, to analyze their public spaces, urban green areas, points of interest, and road networks, and how they address healthy cities criteria. We develop an original methodological approach that combines an index of proximity, accessibility, quantity, and quality of these spaces with geospatial and network analysis techniques. Results indicate that the connectivity and structure of these spaces are centralized and nodal, representing exclusion and segregation. This work provides insights on potential healthy spaces, and information to urban planners and policymakers in decision-making for healthy urban infrastructure.

Existing studies provide evidence that buildings and the construction sector are the largest consumers of natural resources and carry the greatest responsibility for greenhouse gas emissions. In order to reverse this situation, future challenges involve utilising the least resources possible. To this end, building refurbishment becomes a crucial strategy given its potential to improve operational energy efficiency and to extend the life span of existing building stock, thereby reducing the environmental impact while also providing social and economic benefits to our cities. Life Cycle Sustainability Assessment (LCSA) has become one of the scientific community’s most widely recognised methodologies for the evaluation of the social, economic, and environmental dimensions (Triple Bottom Line), since it assesses sustainability using quantitative metrics. However, the implementation of this methodology to support the refurbishment process at the project stage in building design tools, such as BIM, remains scarce. One of the main obstacles lies in the difficulties of accessing the building information, given that the system boundaries only cover new materials and products. Hence, this study proposes a BIM plug-in development to support the multi-dimensional building material selection in the early design steps based on the LCSA of a building during the refurbishment stage and validates its application in a case study. The results show the viability of using this tool during the early design stages and demonstrate the consistency of the results to evaluate various material and product alternatives for the refurbishment of the envelope system of a multi-family residential building. This study contributes towards the integration of decision-making by providing real-time assessment of the building envelope.

From 2020 to 2023 many people around the world were forced to wear masks for large proportions of the day based on mandates and laws. We aimed to study the potential of face masks for the content and release of inanimate toxins. A scoping review of 1003 studies was performed (database search in PubMed/MEDLINE, qualitative and quantitative evaluation). Twenty-four studies were included (experimental time 17 min to 15 days) evaluating content and/or release in 631 masks (273 surgical, 228 textile and 130 N95 masks). Most studies (63%) showed alarming results with high micro- and nanoplastics (MPs and NPs) release and exceedances could also be evidenced for volatile organic compounds (VOCs), xylene, acrolein, per-/polyfluoroalkyl substances (PFAS), phthalates (including di(2-ethylhexyl)-phthalate, DEHP) and for Pb, Cd, Co, Cu, Sb and TiO₂. Of course, masks filter bacteria, dirt and plastic particles and fibers from the air we breathe and have specific indications, but according to our data they also carry risks. Depending on the application, a risk-benefit analysis is necessary. However, mask mandates during the SARS-CoV-2 pandemic have been generating an additional source of potentially harmful exposition to toxins at population level with almost zero distance to the airways.

The article focuses on the integrated environmental accounting model called 'eValue', developed for protected areas and applied in the research programme coordinated by the Italian Ministry of the Environment and aimed at implementing an environmental accounting system for Italian Marine Protected Areas (MPAs). eValue adopts a cost-benefit analysis approach. Financial accounting based on costs and revenues is integrated with environmental accounting, which reflects environmental costs and environmental revenues, i.e. environmental benefits. The environ-mental costs assess the impacts related to human activities in the MPA expressed by calculating the carbon footprint and the environmental benefits of the marine ecosystem services calculated by applying monetary valuation techniques. The values thus estimated flow into the annual flow account, where the value produced (or consumed) by the MPA is estimated by difference. The eValue model was applied to the Porto Cesareo MPA (Italy). eValue showed that the annual benefit-cost ratio reaches a value of 3.4. Furthermore, the ratio of net benefit to public funding is 3.7, completely covering the amount of public transfers and thus summarizing the MPA overall value for money.

Economic risks for livestock production are caused by volatile commodities and market conditions, but also by environmental drivers like increasing uncertainties due to weather anomalies and global warming. These risks impact the gross margin of farmers and can stimulated investment decisions. For confined pig and poultry production, farmers can reduce the environmental impact by implementing specific adaptation measures to reduce heat stress. A simulation model driven by meteorological data was used to calculate heat stress impact as a projection for 2030. For a business-as-usual livestock building, the indoor climate for several adaptation measures was calculated. The weather-related value-at risk quantified the economic risks caused by global warming and the stochastic component of the weather. The results show that only energy-saving adaptation measures to reduce the inlet air temperature are appropriate to reduce the economic risk to the level of the year 1980. The efficiency of other adaptation measures to reduce heat stress is distinctly lower. The results in this study can support the decision making of farmers concerning adaptation management and investments. It can inform agricultural policy design as well as technological development.

Electricity distribution network operators face several operational constraints in the provision of safe and reliable power given that investments for network area reinforcement must be commensurate with improvements in network reliability. This paper provides an integrated approach for assessing the impact of different operational constraints on distribution network reliability by incorporating component lifetime models, time-varying component failure rates as well as the monetary cost of customer interruptions in an all-inclusive probabilistic methodology that applies a time-sequential Monte Carlo simulation. A test distribution network based on the Roy Billinton test system is modelled to investigate the system performance when overloading limits are exceeded as well as when preventive maintenance is performed. Standard reliability indices measuring the frequency and duration of interruptions, and the energy not supplied are complemented with a novel monetary reliability index. The comprehensive assessment includes not only average indices but also their probability distributions to adequately describe the risk of customer interruptions. Results demonstrate the effectiveness of this holistic approach as the impacts of operational decisions are assessed from both reliability and monetary perspectives. This informs network planning decisions through optimum investments and consideration of customer outage costs.

The doctoral defense is an important step in the doctoral journey and an essential requirement for obtaining the doctoral degree. Past research on the doctoral defense has focused solely on national practices. In this work, I investigate the potential link between the doctoral defense format based on its major and minor elements and the perception of the defense by the student. For this purpose, I first reviewed the different defense formats used internationally to extract the different elements of the doctoral defense, as well as the literature on students’ perceptions of the doctoral defense. Then, I carried out an international survey which received 297 responses, of which 204 completed surveys which I used for the analysis in this article. I first analyzed the outcomes of the survey using qualitative and quantitative methods, and then cross-correlated the outcomes of defense format to the outcomes of student perception. From this analysis, I observe that the defense elements that positively impact the students’ perception are: publication of the thesis before the defense, receiving committee feedback before the defense, knowing the recommendation of one or more committee members in advance, having the supervisor present in the audience or as part of the committee, using a dress code, and including a laudatio. The final conclusion of this work is threefold. The first conclusion is that the details of the defense format impact most the students’ perception. The second conclusion is that doctoral students on average value the defense as a positive experience. The third conclusion is that the defense format cannot influence two important aspects of how a student perceives the defense: the student’s inner life and lived experience during the defense, and the behavior of the committee members.

Introduction: Despite the introduction of increasingly multifaceted diagnostic techniques and the general progress of emergency abdominal and vascular surgery, the outcome of treatment of patients with acute impaired intestinal circulation remains unsatisfactory. The non-invasive and high-resolution technique of optical coherence tomography (OCT) can be used intraoperatively to assess intestine viability and associated conditions that frequently emerge under conditions of impaired blood circulation. This study aims to demonstrate the effectiveness of multimodal (MM) OCT for intraoperative diagnostics of both the microstructure (cross-polarization OCT mode) and microcirculation (OCT angiography mode) of the small intestine wall in patients with acute mesenteric ischemia (AMI). Methods and Participants: A total of 18 patients were enrolled in the study. Nine of them suffered from AMI in segments II-III of the superior mesenteric artery (AMI group), where the ischemic segments of the intestine were examined. Nine others were operated for adenocarcinoma of the colon (control group), thus allowing areas of their normal small intestine to be examined for comparison. Data on the microstructure and microcirculation in the walls of the small intestine were obtained intraoperatively from the side of the serous membrane using the MM OCT system (IAP RAS, Russia) before bowel resection. The MM OCT data were compared with the results of histological examination. Results: The study finds that MM OCT visualized the damage to serosa, muscularis externa, and blood vessels localized in these layers in 100% of AMI cases. It also visualized the submucosa in 33.3% of AMI cases. The MM OCT image of non-ischemic (control group), viable ischemic and necrotic small intestines (AMI group) differed significantly across stratification of the distinguishable layers, the severity of intermuscular fluid accumulations and the type and density of the vasculature. Conclusion: The MM OCT diagnostic procedure optimally meets the requirements of emergency surgery. Data on the microstructure and microcirculation of the intestinal wall can be obtained simultaneously in real time without requiring contrast agent injections. The depth of visualization of the intestinal wall from the side of the serous membrane is sufficient to assess the volume of the affected tissues. However, the methodology for obtaining MM OCT data needs to be improved to minimize the motion artefacts generated in actual clinical conditions.

Background: Low-level physical activity (PA) among Chronic Low Back Pain (cLBP) is associated with various biopsychosocial factors. This research aimed to study the predictors of PA behavior among cLBP patients. Methods: In the present study 300 eligible patients with cLBP who referred to comprehensive health service centers in the Shahid Beheshti University of Medical Sciences (SBUMS) in Tehran, Iran were random selected.To diagnose the predictors of PA behavior, all the Theory of Reasoned Action (TRA) constructs were examined as risk factors to see if they influence on the probability of PA behavior occurrence and were interpreted through odds ratio (OR). SPSS version 19 was used to analyze the data. Results: Totally 280 cLBP patients with mean age of 57.07 ±13.09 years old participated in the study. This study showed that motivation to comply significant predictor the cLBP patients for subjective norm OR (%95CI): 2.095(0.116-2.792), p-value<0.001), intention was significant predictor for perform the PA behavior OR (%95CI): 1.431(0.138-1.538), p-value <0.001), behavior beliefs could predictor for attitude OR (%95CI): 1.276(0.106-1.355), p-value= 0.002). attitude, normative beliefs, subjective norm ,and evaluation outcome behavior could predictors the cLBP patients for intention to perform the PA behavior OR (%95CI): 1.188(0.032-1.312), p-value<0.001)., OR (%95CI): 1.158(0.076-2.208), p-value=0.003) ., OR (%95CI): 1.104(0.076-1.128), p-value<0.001) ., OR (%95CI): 0.814(0.301-1.440), p-value=0.007). Conclusions: This study showed that the cLBP patients who were normative beliefs and evaluation regarding PA behavior could effect on the intention to engage in greater PA than those via other constructs (attitude and subjective norm). This study showed that the cLBP patients who were normative beliefs and evaluation regarding PA behavior could effect on the intention to engage in greater PA than those via other constructs (attitude and subjective norm). This study showed that the cLBP patients who were normative beliefs and evaluation regarding PA behavior could effect on the intention to engage in greater PA than those via other constructs (attitude and subjective norm).

This work describes a new transducer prototype for continuous monitoring both in the structural and geotechnical fields. The transducer is synthetically constituted by a wire of optical fiber embedded between two fiber tapes (fiberglass or carbon fiber) and glued by a matrix of polyester resin. The fiber optical wire ends have been connected to a control unit whose detection system is based on Brillouin optical time-domain frequency analysis. Three laboratory tests were carried out to evaluate the sensor's reliability and accuracy. In each experiment, the transducer was applied to a sample of inclinometer casing sets in different configurations and with different constraint conditions. The experimental data collected were compared with theoretical models and with data obtained from the use of different measuring instruments to perform validation and calibration of the transducer at the same time. Several diagrams allow comparing the transducer and highlighting its suitability for monitoring and maintenance of structures. The characteristic of the transducer suggests its use as a mixed system for reinforcing and monitoring, especially in lifetime maintenance of critical infrastructures such as transportation and service networks, and historical heritage.

The introduction of the Internet of Things (IoT), i.e. the interconnection of embedded devices over the Internet, has changed the world we live in from the way we measure, make calls, print information and even the way we get energy in our offices or homes. The convenience of IoT products, like CCTV cameras, IP phones, and oscilloscopes, is overwhelming for end-users. In parallel, however, security issues have emerged and it is essential for infrastructure providers to assess the associated security risks. In this paper, we propose a novel method to detect IoT devices and identify the manufacturer, device model, and the firmware version currently running on the device using the page source from the web user interface. We performed automatic scans of the large-scale network at the European Organization for Nuclear Research (CERN) to evaluate our approach. Our tools identified 233 IoT devices that fell into eleven distinct device categories and included 49 device models manufactured by 26 vendors from across the world.

A study of the water quality of the Adolfo López Mateos Reservoir (ALMD) was developed through different indicators from a spatial and seasonal perspective. Variables related to the general characteristics of water quality, trophic level and ecological risk were assessed through the water Quality Index (WQI_NSF-BROWN), Trophic State Index (TSI_CARLSON) and the Ecological Risk Index (RI_HAKANSON). Using data from physical, chemical and biological parameters obtained from four sampling points in the ALMD, the water quality was assessed in each model used. The results indicated that the reservoir presents a water quality classified as “medium” (WQI_NSF-BROWN = 70), where significant variations in the concentrations of some parameters are observed. The reservoir showed a general trophic state classified as “Mesotrophic” (TSI_{GENERAL-AVERAGE} = 43.04). The ecological risk analysis achieved the best classification of the methodology, discarding contamination by heavy metals in surface waters. Through this type of applied methodologies will help as decision making tools in the dam, as well as for application in other dams in the region.

The purpose of work is to quantify the changes of the organism functional reserves during the successive phases of the human health Space-Time Continuum (STC) on the basis of postulates of reliability complex systems theory. The study is devoted to the problem of age-related human involution, which is evaluated not from the causal, but from the kinetic point of view. The analysis of 10 most important basic life support systems of human body — cardiovascular (CVS), respiratory (RS), nervous (NS), digestive (DS), endocrine (ES), immune (IS), excretory (EXS), brain (BS), musculo-skeletal (MSS), hematopoietic (HS) was carried out. Based on this analysis two levels of ensuring the reliability of organism’s work were revealed: sequential and parallel. The system of logical equations for reduced sequential system is: Ys1 = CVS ∧ RS ∧ BS, where ∧ is the notation for the conjunctions of set elements. The system of logical equations for the reduced parallel system is: Ys2 = NS ∨ DS ∨ ES ∨ IS ∨ HS ∨ EXS ∨ MSS ,where ∨ is the disjunction of the scheme elements. Visualization of human STC changes the concept of the kinetics of age-related changes in the organism and the role of determinants of health as a stable factor accompanying a uniform, smooth transition from the most pronounced functions of the body to their gradual extinction. For human STC is formulated the following regularity kinetics of involutionary processes: after 30 years of age in the human body morphological changes regress in arithmetic progression, and the functions of organs in a geometric one. Assumption of health as a state redundancy of functions is suggested.

The extensive use of engineered nanoparticles (ENPs) such as zinc oxide nanoparticles (ZnO NPs) in various commercial fields has spurred significant concern about its possible toxicological effects of ZnO NPs on human health and eco-system. Therefore, it is substantial to understand the aggregation phenomena which could attenuate this effect. This data article provides information on aggregation of ZnO NPs under the influence of various parameters of water chemistry. Moreover, Taguchi orthogonal array L27(313) design matrix was used to evaluate the effect of multiple parameters in aqueous solution. The data were obtained from single beam UV-Vis spectrophotometer (Optizen 2120 UV, Mecasys, Korea) using Optizenview 4.2.5 PC interference software, Fourier transform infrared spectrometer (FT/IR-4700, spectroscopy, JASCO Analytical Instruments, Easton, USA) and particle electrophoresis (NanoZS, Zetasizer, Malvern Instruments Ltd, Worcestershire, UK). The dataset draws attention on dominant parameters influencing aggregation of ZnO NPs in water. The analysis of variance (ANOVA) data revealed that electrolyte concentration, type and natural organic matter (NOM) concentration were the most significant parameters. Furthermore, FT-IR data presents a possible mechanism of ZnO NPs stabilization in the presence of different NOM. This data will be helpful for the development of environmental risk assessment strategies and prediction of fate and mobility of other ENPs in the aquatic environment.

Oil immersed paper insulation condition is a crucial aspect of power transformer’s life condition diagnostic. The measurement testing database collected over the years made it possible for researchers to implement classification analysis to in-service power transformer. This article presents classification analysis of transformer oil-immersed paper insulation condition. The measurements data (dielectric characteristics, dissolved gas analysis, and furanic compounds) of 149 transformers with primary voltage of 150 kV had been gathered and analyzed. The algorithm used for developing classification model is Support Vector Machine (SVM). The model has been trained and tested using different datasets. Different models have been created and the best chosen, resulting in 90.63% accuracy in predicting the oil-immersed paper insulation condition. Further implementation was executed to classify oil-paper condition of 19 Transformers which Furan data is not available. The classification results combined, reviewed, and compared to conventional assessment methods and standards, confirming that the model developed has the ability to do classification of current oil-paper condition based on Dissolved Gasses and Dielectric Characteristics.

Oil has become the object of global exploits and fierce competition among the major world powers as it is a key strategic non-renewable resource. Transnational petroleum investment is therefore an important mechanism available to countries and international corporations to control oil resources even though there are numerous inherent uncertainties and risks. A new risk assessment index system is proposed in this paper based on use of the Delphi expert scoring system and fuzzy comprehensive evaluation that aims to minimize the potential risks inherent to multinational petroleum investment. This approach encapsulates political, legal, socioeconomic, and infrastructural factors to develop a technical method that can be used for transnational petroleum investment risk assessment. An evaluation of oil investment risk within a case study area is also presented; results provide reference data that can be applied by national and international oil companies to mitigate risks of transnational oil investment.

Compared with conventional methods of fault diagnosis for power transformers, which have defects such as imperfect encoding and too absolute encoding boundaries, this paper systematically discusses various intelligent approaches applied in fault diagnosis and decision making for large oil-immersed power transformers based on dissolved gas analysis (DGA), including expert system (EPS), artificial neural network (ANN), fuzzy theory, rough sets theory (RST), grey system theory (GST), swarm intelligence (SI) algorithms, data mining technology, machine learning (ML), and other intelligent diagnosis tools, and summarizes existing problems and solutions. From this survey, it is found that a single intelligent approach for fault diagnosis can only reflect operation status of the transformer in one particular aspect, causing various degrees of shortcomings that cannot be resolved effectively. Combined with the current research status in this field, the problems that must be addressed in DGA-based transformer fault diagnosis are identified, and the prospects for future development trends and research directions are outlined. This contribution presents a detailed and systematic survey on various intelligent approaches to faults diagnosing and decisions making of the power transformer, in which their merits and demerits are thoroughly investigated, as well as their improvement schemes and future development trends are proposed. Moreover, this paper concludes that a variety of intelligent algorithms should be combined for mutual complementation to form a hybrid fault diagnosis network, such that avoiding these algorithms falling into a local optimum. Moreover, it is necessary to improve the detection instruments so as to acquire reasonable characteristic gas data samples. The research summary, empirical generalization and analysis of predicament in this paper provide some thoughts and suggestions for the research of complex power grid in the new environment, as well as references and guidance for researchers to choose optimal approach to achieve DGA-based fault diagnosis and decision of the large oil-immersed power transformers in preventive electrical tests.

This paper develops a novel dynamic correction method for the reliability assessment of large oil-immersed power transformers. First, with the transformer oil-paper insulation system (TOPIS) as the target of evaluation and the winding hot spot temperature (HST) as the core point, an HST-based static ageing failure model is built according to the Weibull distribution and Arrhenius reaction law, in order to describe the transformer ageing process and calculate the winding HST for obtaining the failure rate and life expectancy of TOPIS. A grey target theory based dynamic correction model is then developed, combined with the data of Dissolved Gas Analysis (DGA) in power transformer oil, in order to dynamically modify the life expectancy calculated by the built static model, such that the corresponding relationship between the state grade and life expectancy correction coefficient of TOPIS can be built. Furthermore, the life expectancy loss recovery factor is introduced to correct the life expectancy of TOPIS again. Lastly, a practical case study of an operating transformer has been undertaken, in which the failure rate curve after introducing dynamic corrections can be obtained for the reliability assessment of this transformer. The curve shows a better ability of tracking the actual reliability level of transformer, thus verifying the validity of the proposed method and providing a new way for transformer reliability assessment. This contribution presents a novel model for the reliability assessment of TOPIS, in which the DGA data, as a source of information for the dynamic correction, is processed based on the grey target theory, thus the internal faults of power transformer can be diagnosed accurately as well as its life expectancy updated in time, ensuring that the dynamic assessment values can commendably track and reflect the actual operation state of the power transformers.

The scarcity and pollution of freshwater are extremely crucial issues today and the expansion of water reuse have been considered as an option to reduce its impact. This study aims to assess the efficiency of an integrated greywater treatment system and hydroponic lettuce production as a part of a green wall structure and to evaluate the health risk associated with the production and consumption of lettuce through quantitative microbial risk assessment (QMRA) and chemical health risk assessment. The study was conducted based on the unique configuration of source separation system; on-site greywater treatment system; green wall structure as a polishing step; and hydroponic lettuce production in the green wall structure. The final effluent from the system was used to grow three lettuce varieties by adding urine as a nutrient solution. Both water samples and plant biomass were collected and tested for E. coli and heavy metals contamination. The system has gained a cumulative 5.1 log10 reduction of E. coli in the final effluent and no E. coli found in the plant biomass. QMRA results indicated that the system attained the health-based targets, 10–6 DALYs per person per year. Similarly, health risk index (HRI) and targeted hazard quotient (THQ) results did not exceed the permissible level, thus the chemical health risk concern was insignificant.

Estimating ground surface PM2.5 with fine spatiotemporal resolution is a critical technique for exposure assessments in epidemiological studies of its health risks. Previous studies have utilized monitoring, satellite remote sensing or air quality modeling data to evaluate the spatiotemporal variations of PM2.5 concentrations, but such studies rarely combined these data simultaneously. We develop a three-stage model to fuse PM2.5 monitoring data, satellite-derived aerosol optical depth (AOD) and community multi-scale air quality (CMAQ) simulations together and apply it to estimate daily PM2.5 at a spatial resolution of 0.1˚ over China. Performance of the three-stage model is evaluated using a cross-validation (CV) method step by step. CV results show that the finally fused estimator of PM2.5 is in good agreement with the observational data (RMSE = 23.00 μg/m^3 and R2 = 0.72) and outperforms either AOD-retrieved PM2.5 (R2 = 0.62) or CMAQ simulations (R2 = 0.51). According to step-specific CVs, in data fusion, AOD-retrieved PM2.5 plays a key role to reduce mean bias, whereas CMAQ provides all-spacetime-covered predictions, which avoids sampling bias caused by non-random incompleteness in satellite-derived AOD. Our fused products are more capable than either CMAQ simulations or AOD-based estimates in characterizing the polluting procedure during haze episodes and thus can support both chronic and acute exposure assessments of ambient PM2.5. Based on the products, averaged concentration of annual exposure to PM2.5 was 55.75 μg/m3, while averaged count of polluted days (PM2.5 > 75 μg/m3) was 81, across China during 2014. Fused estimates will be publicly available for future health-related studies.

Diet is considered a possible cofactor that affects the immune system and potentially could cause dysregulation of intestinal homeostasis and inflammation. This study aimed to review the evidence on specific diet composition effects on some immune-mediated inflammatory diseases (IMID) -rheumatoid arthritis (RA), psoriatic arthritis, spondyloarthritis, multiple sclerosis (MS), Inflammatory bowel disease (IBD) [remission maintenance of Crohn´s disease and ulcerative colitis] and psoriasis- symptoms in adult patients. We conducted a rapid review of meta-analyses and Cochrane systematic reviews using PubMed, EMBASE, from inception to September 2024, and Google Scholar. The methodological quality of meta-analyses was assessed using AMSTAR 2 rating. Three COCHRANE systematic reviews and eight meta-analyses Some specific composition diets have been shown to reduce symptoms in RA, IBD, and MS; and improve some activity parameters in IBD and RA; with critically low, or low levels of evidence. The reduction in inflammatory biomarker levels is unclear. This review updates the global dietary evidence to improve IMID symptoms, discusses the influences of dietary mechanisms, clarifies the weaknesses of clinical trials and dietary meta-analyses, with critically low, or low levels of evidence, and shows the need to use indexes such as DII, that allow diets to be classified for their content of pro-inflammatory or anti-inflammatory foods, to better compare diet groups in clinical trials. The difficulty in obtaining high-level evidence in dietary studies is apparent, which may delay the application of the results.

Probiotics, as defined by the World Health Organization, are live microorganisms that, when consumed in sufficient quantities, provide health benefits to the host. Although some countries have approved specific probiotic species for use in food, safety concerns may still arise with individual strains. Lacticaseibacillus paracasei subsp. paracasei NTU 101 (NTU 101), isolated from the gut of healthy infants, has demonstrated various probiotic effects and shown safety in prior 28-day animal feeding study. To further verify its safety and mitigate potential risks, we performed a comprehensive genotypic and phenotypic safety evaluation in accordance with European Food Safety Authority guidelines for safety assessment through whole genome sequencing and related literature. In this research, minimum inhibitory concentration testing identified NTU 101's resistance to chloramphenicol; however, subsequent gene analysis confirmed no associated risk of resistance. Assessments of safety, including biogenic amine content, hemolytic activity, mucin degradation, and D-lactic acid production, indicated a low level of risk. Additionally, a repeated dose 90-day oral toxicity study in Sprague-Dawley rats revealed no toxicity at a dose of 2000 mg/kg body weight, further supporting the strain's safety for consumption. Based on these comprehensive analyses, NTU 101 is considered safe for regular consumption as a health supplement.

In today’s rapidly evolving digital landscape, the significance of password guessing techniques in both offensive and defensive strategies is paramount. Passwords serve as a crucial line of defense for both individuals and corporations, safeguarding their sensitive systems and data. Therefore, assessing the effectiveness of these access credentials is a critical task. However, existing research in this field often encounters limitations, such as a lack of sufficient training data and extended model training times. Current methods often struggle with limited training data and lengthy training times. This paper introduces BBPE-AE, a novel Auto Encoder Network (AE) designed for password guessing. BBPE-AE utilizes Byte-level Byte Pair Encoding (BBPE) to extract frequent tokens from password datasets without length restrictions, employing a dynamic window technique to capture complex patterns. Experimental results on Hotmail and Myspace datasets demonstrate exceptional performance, achieving high similarity rates (BLEU-Unigram: 0.90, BLEU-Bigram: 0.82 for Hotmail; BLEU-Unigram: 0.90, BLEU-Bigram: 0.81 for Myspace). BBPE-AE generates realistic passwords that meet HIBP (Have I Been Pwned) standards, minimizing duplication. These findings highlight the effectiveness of BBPE-AE in enhancing security by generating realistic passwords, ultimately safeguarding sensitive systems and data.

Surveys on the optimum seismic design of structures reveal that many investigations focus on how to minimize its initial cost while satisfying the performance constraints. Although reducing the initial cost while complying with the requirements of earthquake design codes of practice will significantly guarantee the life safety of occupants against earthquakes, it may still cause considerable economic losses to residents and fatalities. Accordingly, calculating the possible earthquake damages caused during the structure's lifetime may become essential from the optimal Life Cycle Cost (LCC) design point of view. LCC analysis is used to evaluate economic feasibility including construction, operation, occupancy, maintenance and end-of-life costs. For optimization, the population-based, meta-heuristic algorithm based on the Ideal Gas Molecular Movement (IGMM), has established its capability in solving highly nonlinear mono and multi-objective engineering problems. Therefore, this paper investigates the LCC -based mono and multi-objective optimum design of a 3-D four-story concrete building structure combined with the Endurance Time (ET) competence. The results show that, apart from substantially reducing the total number of analyses required, the proposed technique significantly affected dipping minor injury cost, rental, and income costs by 22%, 16%, and 16%, respectively. In total, a 10% reduction in all structural life-cycle costs was achieved, which could well be considered significant.

Grasping the spatial and temporal patterns of forest fires, along with the key factors that drive them and the ability to forecast such events accurately, is essential for the successful management of forests. In China's southern region, forest fires significantly endanger the ecological system, public safety, and economic well-being. Through the application of Geographic Information Systems (GIS) and LightGBM (Light Gradient Boosting Machine) model, this study investigates the determinants of fire incidents and formulates a predictive model for forest fire occurrences, alongside a zoning strategy, within the Central-South area. The results indicate: (i) Spatially, fire points exhibit significant clustering and autocorrelation characteristics; (ii) The Central-South Forest Fire Prediction Model shows exceptional accuracy, reliability, and predictive power, with high performance metrics across training and validation sets, including over 85% accuracy, precision, recall, and F1 scores, along with AUC values above 89%, underscoring its efficacy in forecasting forest fires and distinguishing between fire events; (iii) Throughout the year, forest fire risks in the Central-South region of China vary by region and season, with risk spikes from March to May in Guangdong, Guangxi, Hunan, Hubei, and Hainan. From June to August, localized risks are observed in Heyuan and Huangshi, while from September to November, an increase in risk is noted in Guangdong (Meizhou, Heyuan, Shaoguan), Guangxi (Nanning, Hezhou, Yulin), and Hunan (Binzhou, Yongzhou, Hengyang) due to cooler, drier conditions and leaf litter accumulation. From December to February, the risk continues in specific areas across Guangdong, Guangxi, Hunan, and Hubei.

In recent years, an interest in multimedia services has grown expeditiously where the main part is comprised of video. Firms as well as subscribers require higher resolutions, framerates and sampling precision which results to higher amount of data need for processing, storing and transmitting. Therefore, a big challenge arises for researchers to develop new compression standards which should reduce the huge amount of data and keep quality at the same level. This paper examines compression performance of the latest and currently most used video codecs, namely H.266/VVC, AV1, H265/HEVC and H.264/AVC. The test set consists of seven sequences with various content at 8K, Ultra HD and Full HD resolution and encoded to bitrates from 1 to 15 Mbps for Full HD and Ultra HD resolutions and from 5 to 50 Mbps for 8K resolution, respectively. Codec performance was measured using PSNR, SSIM and VMAF objective quality metrics. In terms of the Bjøntegaard-Delta (BD) model, the results showed that H.266/VVC outperforms all other codecs, namely H.264/AVC,H.265/HEVC and AV1, respectively. Averaged bitrate savings were approximately 78\% for H.266/VVC, 63\% for AV1 and 53\% for H.265/HEVC relative to H.264/AVC, 59\% for H.266/VVC, 22\% for AV1 compared to H.264/AVC and 46\% for H.266/VVC relative to AV1, all for 8K resolution. The results also showed that the performance varies depending on resolution – with higher resolution, the efficiency of newly developed codecs such as H.266/VVC and AV1 is greater, which confirmed the fact that the H.266/VVC and AV1 codecs have been primarily developed for videos at high resolutions as 8K and/or UHD.

Smart home and building systems are popular solution that support maintaining comfort, safety and improving energy efficiency in buildings. However, dynamically developing distributed network technologies, in particular the Internet of Things, are increasingly entering the above-mentioned application areas of building automation, offering new functional possibilities. The result of these processes is the emergence of many different solutions that mix technologies of field-level and ICT networks in various configurations and architectures. New paradigms are also emerging, such as edge and fog computing, providing support for local monitoring and control networks in the implementation of advanced functions and algorithms, including machine learning and artificial intelligence mechanisms. This paper collects state-of-the-art information in these areas, along with a systematic review of the literature, case-studies and an analysis of selected development trends. The author systematized this information in the context of the potential development of building automation systems. Based on the conclusions of this analysis and discussion, a framework for the development of the Generic IoT paradigm in smart home and building applications has been proposed, along with a SWOT analysis of its usability. Future works are proposed as well.

In the construction business, which is known for its intricate and strategic nature, it is crucial to have efficient risk management in place. This is because various internal and external elements can cause disruptions to projects. Although the industry has had a historically negative reputation for risk analysis, the methodical process of identifying, analyzing, and managing risks has been more widely recognized and respected. This paper examines the historical progression of construction risk management, highlighting the need to identify and classify risks promptly. The study examines various risk factors related to finance, law, environment, and logistics. The study explores various risk management strategies, such as contract management, risk distribution, evaluation, mitigation, and sharing. The article discusses the significant impact of risk management software, such as Procore, PlanGrid, e-Builder, Autodesk BIM 360, and Oracle Primavera, on improving project results. The study finishes by highlighting the importance of proactive risk management in protecting against financial losses and maintaining a reputation in the construction business.

This paper examines the use of business maturity models as a tool for achieving business maturity and improving organizational performance in a rapidly changing business environment. Specifi-cally, the paper evaluates existing maturity models and methodologies, analyzes their effective-ness, and develops a novel and enhanced model tailored to the oil and gas sector. The authors highlight the importance of considering fundamental factors that underlie the implementation of maturity models and the need to evaluate their fit with organizational goals and values. The pa-per concludes by emphasizing the ongoing nature of business maturity and the effectiveness of theproposed Business Maturity Framework (BMF) model in enhancing operational excellence, competitiveness, and sustainable growth in the oil and gas industry. The paper makes a notable contribution to the specialized literature precisely through the differ-ent approaches to the business maturity process and through the proposed business maturity model itself as a base of strategy formulation, which includes a new dimension. This dimension analyzes whether the market and customers are ready for the level of digitization that the com-pany wants to achieve in a future state.

The 3D/3D+ multidimensional geriatric assessment tool provides an optimal model of emergency care for patients aged 75 and over who attend the Emergency Department (ED). The baseline, or static, component (3D) stratifies the degree of frailty prior to the acute illness, while the current, or dynamic, component (3D+) assesses the multidimensional impact caused by the acute illness and helps to guide the choice of care facility for patients upon their discharge from the ED. The objective of this study was to evaluate the prognostic value of the 3D/3D+ to predict short- and long-term adverse outcomes in ED patients aged 75 years and older. Multivariable logistic regression models were used to identify the predictors of mortality 30 days after 3D/3D+ assessment. Two hundred and seventy-eight patients (59.7% women) with a median age of 86 years (interquartile range: 83-90) were analysed. According to the baseline component (3D), 83.1% (95%CI: 78.2-87.3) presented some degree of frailty. The current component (3D+) presented alterations in 60.1% (95%CI: 54.1-65.9). The choice of care facility at ED discharge indicated by the 3D/3D+ was considered appropriate in 96.4% (95%CI: 93.0-98.0). Thirty-day all-cause mortality was 19.4%. Delirium and functional decline were the dimensions on the 3D/3D+ that were independently associated with 30-day mortality. These two dimensions had an area under receiver operating characteristic of 0.80 (95%CI: 0.73-0.86) for predicting 30-day mortality. 3D/3D+ enhances the provision of comprehensive care by ED professionals, guides them in the choice of patients’ discharge destination, and has a prognostic validity that serves to establish future therapeutic objectives.

The functional capacity of the cervical spine plays a central role in healthy living. This study evaluated and created a comprehensive strength, range of motion (ROM), and musculoskeletal pain profile of the cervical spine in young adults. 60 physically active individuals (30 males/30 females; 19-24 year-old) participated in the study. Cervical ROM (forward flexion, extension, lateral flexion, and rotation), maximal isometric strength (forward flexion, extension, lateral flexion), and musculoskeletal pains were assessed using an electronic goniometer, a handheld dynamometer, and the Nordic questionnaire, respectively. Data analysis revealed that: a) fe-males had higher ROM values, during extension and lateral flexion, than males (p<0.05), b) males had higher absolute strength values than females in all movement directions, higher rela-tive strength values/body mass (at forward flexion) and flexion/extension ratio values (p<0.05), c) ROM and strength values were not significantly different between right-left sides (p>0.05), d) a great proportion (43.3%) of the participants had cervical pains (no sex-related differences) and e) cervical strength showed significant small negative correlation with pains (p<0.05; r=-0.225 to -0.345). The reference values created may be used by health and fitness professionals to exten-sively evaluate the cervical spine and to design specific exercise programs for injury prevention and rehabilitation.

Objective: This study assessed hearing aid benefits for people with a normal audiogram but hearing-in-noise problems in everyday listening situations. Design: Exploratory double-blinded case control study whereby participants completed retrospective questionnaires, ecological momentary assessments, speech-in-noise testing, and mental effort testing with and without hearing aids. Twenty-seven adults reporting speech-in-noise problems but normal air-conduction pure-tone audiometry took part in the study. They were randomly separated into an experimental group who trialled mild-gain hearing aids with advanced directional processing and a control group fitted with hearing aids with no gain or directionality. Results: Self-reports showed mild-gain hearing aids reduce hearing-in-noise difficulties and provide a better hearing experience (i.e., improved understanding, participation, and mood). Despite the self-reported benefits, the laboratory tests did not reveal a benefit from the mild-gain hearing aids, with no group differences on speech-in-noise tests or mental effort measures. Further, participants found the elevated cost of hearing aids to be a barrier for their adoption. Conclusions: Hearing aids benefit the listening experience in some listening situations for people with normal audiogram who report hearing difficulties in noise. Decreasing the price of hearing aids may lead to greater accessibility to those seeking remediation for their communication needs.

The World Health Organization estimates that every year air pollution kills seven million people worldwide. As it is expected that climate change will affect future air quality patterns, the full understanding of the links between air pollution and climate change, and how they affect human health, are challenges of future research. In this scope, a methodology to assess the air quality impacts on health was developed. The WRF-CAMx modelling framework was applied for the medium-term future climate (considering the SSP24.5 scenario) and for the recent past (considered as baseline). Following the WHO recommendations, mortality health indicators were used to estimate health impacts of long-term exposures. For that, the Aveiro Region, in Portugal, was considered as a case study. Future climate results indicate the occurrence of higher temperatures, and lower total precipitation. Despite that, improvements in the main pollutants’ concentrations, and consequently in the reduction of the related premature deaths are foreseen, mainly due to the reduction of pollutants emissions imposed by the European legislation for the upcoming years. The applied approach constitutes an added value in this research field, being crucial to anticipate the effects of climate change on air quality and evaluate their impacts on human health.

The health of the landing gear retraction and extension hydraulic system may be assessed using fuzzy comprehensive evaluation (FCE), however the traditional FCE method depends solely on human assessment by specialists, which is excessively subjective. To address the issue of excessive human subjective variables in the assessment, an improved FCE model based on enhanced risk coefficient is provided, which includes four consideration indexes: failure probability, failure severity, failure detection difficulty, and failure repair difficulty. To reduce subjective human judgment errors entirely due to expert experience, the improved FCE takes into account the likelihood of failure using a statistical method, the severity of failure using a fault simulation analysis based on the LMS Imagine.Lab AMESim simulation platform, and the difficulty of fault detection and repair using the aircraft manufacturer's professional maintenance information. As part of the evaluation model, the range of health assessment values and accompanying treatment methods are included, making it easier to implement on a daily basis in aircraft maintenance. As a final step, the simulation is evaluated and the simulated faults are calculated.

Partial shading on solar photovoltaic (PV) arrays is a prevalent problem in photovoltaic systems that impair the performance of PV modules and is responsible for reduced power output as compared to that in standard irradiance conditions thereby resulting in the appearance of multiple maximas on panel output power characteristics. These maxims contribute to mismatch power losses among PV modules. The mismatch losses depend on shading characteristics together with different interconnected configuration schemes of PV modules. The research presents a comparative analysis of partial shading effects on a 4 x4 PV array system connected in series(S), parallel (P), serries-parallel (SP),total-cross-tied (TCT),central-cross-tied(CCT),bridge-linked(BL),bridge-linked total cross-tied (BLTCT) ,honey-comb(HC), honey-comb total-cross-tied (HCTCT) and ladder (LD) configurations using MATLAB/Simulink. The PV module SPR-X20-250-BLK was used for modeling and simulation analysis. Each module is comprised of 72 number of PV cells and a combination of 16 PV modules was employed for the contextual analysis. Accurate mathematical modeling for the HCTCT configuration under partial shading conditions (PSCs) is provided for the first time and is verified from the simulation. The different configuration schemes were investigated under short-narrow,short-wide,long-narrow,long-wide, diagonal, entire row distribution, and entire column distribution partial shading condition patterns with mathematical implementation and simulation of passing clouds. The performance of array configurations is compared in terms of maximum power generated ), mismatch power loss (∆), relative power loss ) and the fill factor (FF). It was inferred that on average, TCT configuration yielded maximum power generation under all shading patterns among all PV modules interconnection configurations with minimum mismatch power losses followed by hybrid and conventional PV array configurations respectively.

The NETTER-1 study has proven peptide receptor radionuclide therapy (PRRT) to be one of the most effective therapeutic options for metastatic neuroendocrine tumors (NETs), improving progression-free survival and overall survival. However, PRRT response assessment is challenging and no consensus on methods and timing has yet been reached among experts in the field. This issue is owing to the suboptimal sensitivity and specificity of clinical biomarkers, limitations of morphological response criteria in slowly growing tumors and necrotic changes after therapy, a lack of standardized parameters and timing of functional imaging, and the heterogeneity of PRRT protocols in the literature. The aim of this article is to review the most relevant current approaches for PRRT efficacy prediction and response assessment criteria in order to provide an overview of suitable tools for safe and efficacious PRRT.

Heart Rate Monitors (HRMs) are an indispensable tool for controlling training parameters of healthy athletes. They became a source of information about stress heart rhythm disturbances, recognized as unexpected increases in heart rate (HR), which can be life-threatening for athletes. Most HRMs do not recognize the type of arrhythmia, confusing them with artifacts. The aim of the study was to assess the usefulness of ECG recording functions by sports HRMs among endurance athletes, coaches, and physicians in comparison with other basic and hypothetical functions. We conducted 3 surveys among endurance athletes (76 runners, 14 cyclists, and 10 triathletes), as well as 10 coaches and 10 sports doctors to obtain information on how important ECG recording is, and what functions of HRMs should be improved to meet their expectations in the future. The respondents were asked questions regarding use and hypothetical functions, as well as preference for HRM type (optical/strap). For athletes, the 4 most important functions were distance traveled, pace, instant heart rate, and information about reaching the oxygen threshold. ECG recording was the 8th and 9th most important for momentary and continuous, respectively. Coaches opined more importance to ECG recording. Doctors placed ECG recording as most important. All participants preferred optical HRMs to strap HRMs. Research on the improvement and implementation of HRM functions shows slightly different preferences of athletes compared to coaches and doctors. Suspected arrhythmia increases the value of the HRM’s ability to record ECGs during training by athletes and coaches. For doctors, this is the most desirable feature in any situation. Considering the expectations of all groups continuous ECG recording during training will significantly improve the safety of athletes.

Wave energy converter (WEC) arrays deployed in coastal regions may create physical disturbances potentially resulting in environmental stresses. Presently, limited information is available on the nature of these physical disturbance or the resultant effects. A quantitative Spatial Environmental Assessment Tool (SEAT) for evaluating potential effects of wave energy converter (WEC) arrays on nearshore hydrodynamics and sediment transport is presented for the central Oregon coast (USA) through coupled numerical model simulations of an array of WECs. Derived climatological wave conditions were used as inputs to the model to allow for the calculation of risk metrics associated with various hydrodynamic and sediment transport variables such as maximum shear stress, bottom velocity, and change in bed elevation. The risk maps provided simple, quantitative, and spatially-resolved means of evaluating physical changes in the vicinity of a hypothetical WEC array in response to varying wave conditions. Near-field risk of sediment mobility was determined to be moderate in the lee of the densely spaced array, where the potential for increased sediment deposition could result in benthic habitat alteration. Modifications to the nearshore sediment deposition and erosion patterns were observed near headlands and topographic features, which could have implications for littoral sediment transport. The results illustrate the benefits of a risk evaluation tool for facilitating coastal resource management at early market marine renewable energy sites.

Changes in extreme weather patterns are expected under climate change. In this study, a risk assessment was conducted using 4 building damage history datasets and 33 weather datasets (precipitation, wind speed, snow, and temperature) from 230 regions in South Korea to quantitatively analyze and predict building damage caused by potential future natural disasters. Decision tree analysis was used to evaluate building damage risk in 230 regions. The decision tree model to determine the risk of flood, gale, and typhoon was generated, which excluded gales, with less damage. The weight (variable importance) and limit value (damage limit) of the weather variables ware derived using the decision tree model. Using these two factors, we assessed the building damage risk in 230 regions in South Korea until 2100. The number of regions at risk of flood damage increased by more than 30% in average. Conversely, regions at risk of snowfall damage decreased by more than 90%. The regions at risk of typhoons decreased by 57.5% on average, and the number of regions at high risk of typhoon damage increased by up to 62.5% in RCP 8.5. These results can be used as objective data to minimize future building damage throughout South Korea, representing the first step towards sustainable development in the region with respect to disaster response.

This paper deals with the environmental characterization of a large and densely populated area, with a poor reputation for contamination, considering the contribution of environmental features (air, soil, soil hydraulic and groundwater) and the potential effects on human health. The use of Geographic Information System (GIS) has made possible a georeferenced inventory and, by overlaying environmental information, an operational synthesis of comprehensive environmental conditions. The cumulative effects on environmental features were evaluated, taking into account superposition effects, by means of the spatial multicriteria decision analysis (S-MCDA). The application of the S-MCDA for converging the combination of heterogeneous factors, related to soil, land and water, deeply studied by heterogeneous groups of experts, constitutes the novelty of the paper. The results confirmed an overall higher potential of exposure to contaminants in the environment and higher mortality rates in the study area for some tumours, but hospital admissions for tumours were generally similar to the regional trend. Besides, mortality data may be strictly dependent on the poor socioeconomic conditions, quality of therapy and a lack of welfare in the area relative to the rest of Italy. Finally, as regards the possible relationship between presence of contaminants in the environment and health conditions of the population no definite conclusions can be drawn, although the present study encourages the use of the new proposed methods, that increase the possibilities for studying the combined effect of more environmental factors.

This study aims to evaluate the performance of a concrete bridge located near the earthen dam of Masjed Soleiman County. The proximity of bridges to large water structures such as dams can affect their structural integrity due to environmental factors and the dynamic loads imposed by fluctuating water levels and soil movements. This paper analyzes the structural behavior of the concrete bridge using advanced modeling techniques, including finite element analysis and site-specific data. The methodology involves evaluating the bridge’s load-carrying capacity, durability under environmental stresses, and possible degradation due to soil settlement and moisture penetration from the nearby dam.Field tests and simulations were conducted to assess the bridge’s stability and performance under different loading conditions, including traffic loads and external factors like changes in water pressure from the dam. Results indicate that while the concrete bridge remains structurally sound, there are signs of minor degradation in certain areas, such as cracks and moisture-related issues. These findings highlight the importance of regular maintenance and monitoring, especially in structures located near large water bodies or dams.Recommendations for improving the bridge’s performance include applying advanced waterproofing methods, strengthening concrete components in critical zones, and implementing a routine inspection schedule. The results from this case study provide valuable insights into the interaction between bridges and surrounding hydraulic infrastructure, serving as a reference for similar projects in regions prone to environmental and structural stresses.This research contributes to the body of knowledge by offering practical solutions for maintaining and enhancing the durability of concrete bridges in close proximity to dams, emphasizing the need for proactive strategies to extend the lifespan of such critical infrastructure.

Following the economic and political transformations after 1991, including the autonomy of the Kurdistan Region and the establishment of Iraq's new federal government in 2003, extensive construction, including mosques, has reshaped the region. This requires examinations of evolving architectural features in new mosques and questioning their alignment with religious and aesthetic design objectives. This research focuses on the transformative impact of modern architectural styles on mosque evolution in Sulaymaniyah Governorate. Acknowledging the interplay of cultural evolution, technology, and artistic innovation, the study employs an in-depth case study approach to analyze selected mosques in Sulaymaniyah Governorate that blend traditional Islamic architecture with modern design principles. This synthesis of traditional and modern elements raises questions about religious legitimacy, historical symbolism, and architecture's role in reflecting and shaping religious values. Using quantitative methods including indicator-based impact assessment, the study identifies modern architectural indicators, determines religious objectives of mosque design through Islamic legitimacy references, and analyzes the case study data. By employing person coefficient correlation, the research aims to identify the causal relationship between modern architectural indicators and achieved design objectives. The results reveal that the overall influence of the modern architecture style tends to be more negative on the evol¬ution of mosques.

Virtual Reality (VR) is increasingly used in neuropsychological assessments due to its ability to simulate real-world environments. This study aimed to develop and evaluate the Trail Making Test in VR (TMT-VR) and investigate the effects of different interaction modes and gaming skills on cognitive performance. A total of 71 young female and male adults (aged 18-35) with high and low gaming skills participated in this study. Participants completed the TMT-VR using three interaction modes: eye-tracking, head movement, and controller. Performance metrics included task completion time and accuracy. User experience, usability, and acceptability of TMT-VR were also examined. Results showed that both eye-tracking and head movement modes significantly outperformed the controller in terms of task completion time and accuracy. No significant differences were found between eye-tracking and head movement modes. Gaming skills did not significantly influence task performance using any interaction mode. Participants reported high usability, acceptability, and user experience for the TMT-VR. Eye-tracking facilitated higher accuracy, while head movement higher speed. The TMT-VR offers high usability and user experience and is well accepted by the participants. The findings suggest that VR-based assessments can effectively measure cognitive performance without being influenced by prior gaming skills, indicating potential applicability for diverse populations.

(1) Background The SKT is a short cognitive performance test designed to assess impairments in memory and cognitive abilities such as attention and speed of information processing. In 2019, new regression-based norms for the English version of the SKT were calculated applying data from older cognitively healthy adults living in the US, Ireland and Australia (the norming sample) The study has two aims: to establish valid cut-offs for distinguishing between no cognitive impairment, mild cognitive impairment (MCI) and dementia (1), and to cross-validate the new norms for detecting MCI and dementia (2) in a community sample of older adults with clinical diagnoses; (2)Methods: The validation sample included 142 older adults (mean age=87.7, SD=3.55) from the Sydney Memory and Aging Study (MAS Study). Participants were classified as having normal cognition, MCI, or dementia through a consensus diagnosis as well as by the SKT; (3)Results: The sensitivity of the SKT for the differentiation of cognitive impairment (MCI or dementia) from normal cognition was 80.6%. The convergence between the SKT and the consensus diagnoses was 60.1% for all three diagnostic groups. The correlation between the SKT and the Addenbrooke’s Cognitive Examination III (ACE-III), a well validated measure of cognitive ability in older adults, was r = 0.3;. (4) Conclusions: In sum, it can be stated that the SKT is a valid tool for detecting early stages of cognitive impairment, performing very well in discriminating between no cognitive impairment and cognitive impairment (MCI or dementia).

Mobile devices (MD) are used by mobile cloud computing (MCC) customers users because of their 11 portability and robust connectivity and the ability to house and operate third-party applications 12 (apps). However, the apps installed on a MD may pose data security risks to the MD owner and to 13 other MCC users, especially when the requested permissions include access to sensitive data (e.g., 14 user’s location and contacts). Calculating the risk score of an app or quantifying its potential 15 harmfulness based on user input or on data gathered while the app is actually running may not 16 provide reliable and sufficiently accurate results to avoid harmful consequences. This study 17 develops and evaluates a risk assessment framework for Android-based MDs that does not depend 18 on user input or on actual app behaviour. Rather, an app risk evaluator assigns a risk category to 19 reach resident app based on the app’s classification (benign or malicious) and the app’s risk score. 20 The app classifier (a trained machine learning model) considers the permissions and the intents 21 requested by the app. The apps risk score is calculated by a probabilistic function based on the 22 app’s use of a set of selected dangerous permissions. The results from the testing of an instance of 23 the framework on a MD with real-life resident apps indicated that the proposed security solution 24 was effective and feasible.

Background: Current management of COPD is predominantly focused on respiratory aspects. A multidimensional assessment including nutritional assessment, quality of life and disability provides a more reliable perspective of the true complexity of COPD patients. Methods: Prospective observational study of 120 elderly COPD patients at high risk of acute exacerbations. The Mini-Nutritional Assessment (MNA) was administered in addition to the usual respiratory assessment. The primary outcome was a composite of moderate or severe acute exacerbations during 52 weeks of follow-up. Results: The median MNA Short Form (SF) score was 11 (8-12), 39 participants (32.50%) had normal nutritional status, 57 (47.5%) were at risk of malnutrition and 24 (20%) were malnourished. Our multivariate linear logistic models showed that the MNA score was associated with dyspnea and respiratory symptoms severity assessed by the Modified British Medical Research Council (mMRC) and the COPD Assessment Test (CAT) score, with spirometric variables, in particular with the severity of airflow limitation based on the value of FEV1 and with poorer QoL as assessed by the EQ-5D-3 questionnaire. Cox regression analysis according to nutritional status based on the MNA score showed that COPD participants "at risk of malnutrition" and "malnourished" had a higher risk of moderate to severe acute exacerbations with a hazard ratio (HR) of 3.54 (p=0.002) and 8.20 (p=0.0001), respectively. Conclusion: Our study confirms the importance of assessing nutritional status in elderly COPD patients and its prognostic value.

The increasing rate of adoption of innovative technological achievements along with the penetration of the Next Generation Internet (NGI) technologies and Artificial Intelligence (AI) in the water sector, are leading to a shift to a Water-Smart Society. New challenges have emerged in terms of data interoperability, sharing, and trustworthiness due to the rapidly increasing volume of heterogeneous data generated by multiple technologies. Hence, there is a need for efficient harmonisation and smart modeling of the data to foster advanced AI analytical processes which will lead to efficient water data management. The main objective of this work is to propose two Smart Data Models focusing on the modeling of the Satellite Imaginary data and the Flood Risk Assessment processes. The utilisation of those models reinforces the fusion and homogenisation of diverse information and data facilitating the adoption of AI technologies for flood mapping and monitoring. Furthermore, a holistic framework has been developed and evaluated via qualitative and quantitative performance indicators revealing the efficacy of the proposed models concerning the usage of the models in real cases. The framework is based on the well-known and compatible technologies on NGSI-LD standards which are customised and applicable easily to support the water data management processes effectively.

To proactively manage information security, enterprises often employ information security risk assessment techniques. Asset value - which is used to calculate the financial impact of possible threats - is one of the key parameters of information security risk. However, assets in a system are rarely independent, and their values are typically interdependent. Asset owners and IT teams may hold different views as regards these values, and there is thus the need to reduce subjectivity in a qualitative risk assessment. The research entails the development of a conceptual framework derived from the literature to minimize subjectivity, and the design of a system based on those concepts. The study uses the Unified Modeling Language as a design tool and puts forward an object-oriented model for defining asset values, in which the relationships between assets, vulnerabilities and related threats are identified. A “segregation of duties” approach is integrated into the risk management system to mitigate against subjectivity and better determine asset values. Survey responses from 16 practitioners working in the private and public sectors confirm the validity of the approach, but suggest it may be more workable in larger organisations where resources allow dedicated risk professionals to operate.

Triangles are an ever present feature in nature, which the building construction industry duly echoes. However, an exact expression intended to offer the radiant field due to any triangle in an upright or inclined position had not been identified by previous research. In this case, the author has been able to solve by direct integration, the canonical expression of radiative transfer. This result alone confers a myriad of possibilities that had been inconceivable before, for studying in detail the three-dimensional heat transfer behavior of volumes and figures in which triangles do manifest, such as fins, windows, roof-gables and louvers of various kinds. Typically, shading devices, when tilted, give rise in their extremes to rhomboidal shapes which were difficult to take into account or had to be subject to discretization and subsequent Monte Carlo methods in order to perform an approximate calculation of their emission. This implied a lengthy and inexact procedure that induced many errors and consumed computing time. We can now avoid all the former downsides due to the advances hereby presented. As the novel expression can be converted into an algorithm it will be advantageously employed for simulation. This significant finding dovetails in the intricate puzzle of radiated heat and we believe that their consequences will greatly affect the conception and design of HVAC devices, aircraft manufacturing and specifically building or lighting industries among others.

Our objective was to evaluate whether pregnancy is prolonged by use of a proteomics-based maternal serum screening test followed by treatment interventions. This is a secondary analysis of the PREVENT-PTB randomized trial comparing screening with the PreTRM test versus no screening. The primary trial analysis found no significant between-group difference in preterm birth rate. Rather than considering a dichotomous outcome (preterm vs term), we treated gestational age at birth as a continuous variable using survival analysis. We also evaluated between-group difference in NICU length of stay and duration of respiratory support. Results indicated that pregnancy was significantly prolonged in subjects screened with PreTRM test compared to controls (adjusted hazard ratio 0.53, 95% confidence interval 0.36-0.78, P &lt;0.01). Newborns of screened subjects had significantly shorter NICU stay but no significant decrease in duration of respiratory support. In the PreTRM screen-positive group, interventions that were associated with pregnancy prolongation included care management and low-dose aspirin but not 17-hydroxyprogesterone caproate. We concluded that screening with the PreTRM test followed by interventions for screen-positive pregnancies can prolong pregnancy and reduce NICU-LOS.

Auricular keloids pose significant aesthetic and functional challenges, and traditional treatments often fall short in ad-dressing these. Our study presents an innovative combined approach of ablative CO2 and dye laser therapy for improved keloid management. This treatment protocol was applied to 15 patients with auricular keloids after an initial multispec-tral analysis to assess keloid composition. The laser sequence was tailored per patient based on this analysis. Evalua-tions using the Vancouver Scar Scale and Patient and Observer Scar Assessment Scale were carried out at baseline and at 3-week intervals post-treatment. The results showed a significant reduction in these scores at the final follow-up (p<0.05), suggesting improvements in keloid color, texture, and pliability, with minimal adverse events. Additionally, no recur-rence of keloids was observed. Our findings indicate that this novel methodology of multispectral analysis followed by tailored laser therapy may offer a safe and effective solution for auricular keloids, promising enhanced keloid treatment and prevention of recurrence. However, further investigations, including randomized controlled trials, are needed to confirm and optimize this treatment protocol.

This research experiments with a sustainability assessment based on the Sustainable Development Goals (SDGs) of Agenda 2030 through a process of their territorialisation and implementation. This process enables the development of a Spatial Decision Support System (SDSS) that can be integrated with strategic environmental assessments in urban planning. The assessment takes place on the transversality of the sustainability concept by trying to consider together the three dimensions (environmental, social and economic) into a single assessment through the Spatial Sustainability Assessment Model (SSAM) by integrating Geographic Information Systems (GIS) and multi-criteria analyses. Economic development, social equity, and ecological integrity represent three common visions for rethinking peri-urban edges.

Digitalization is globally transforming the world with profound implications. It has enormous potential to foster progress toward sustainability. However, in its current form, digitalization also continues to enable and encourage practices with numerous unsustainable impacts affecting our environment, ingraining inequality, and degrading quality of life. There is an urgent need to identify such multifaceted impacts holistically. Impact assessment of digital interventions (DIs) leading to digitalization is important specifically for Sustainable Development Goals(SDGs). Action is required to understand the pursuit of short-term gains toward achieving long-term value-driven sustainable development. We need to understand the impact of DIs on various actors and in diverse contexts. A holistic understanding of the impact it creates will help us align it with visions of sustainable development and identify potential measures to mitigate negative short and long-term impacts. The recently developed Digitainability Assessment Framework (DAF) unveils the impact of DIs with an in-depth context-aware assessment and offers an evidence-based impact profile of SDGs at the indicator level. We performed the impact assessment of diverse technologies using DAF. This paper summarizes the insights from the Digitainable Spring School 2022 on "Sustainability with Digitalization and Artificial Intelligence," one of whose goals was to operationalize the DAF as a tool in the action learning process with diverse professionals in the field of digitalization and sustainability. The DAF guides a holistic context-aware process formulation for a given DI. An evidence-based evaluation within the DAF protocol benchmarks a specific DI’s impact against the SDG indicators framework. The operationalization of the DAF was carried out by looking at four different DIs: smart home technologies (SHT) for energy efficiency, blockchain for food security, artificial intelligence for land use cover and changes (LUCC), and big data for international law. Each of the four studies addresses different DIs for digitainability assessment using different techniques for a diverse group of indicators, demonstrating the potential of the DAF but also outlining the existing data gaps that limit a comprehensive analysis.

The ISO 2859 and ISO 3951 series provide acceptance sampling procedures for lot inspection, allowing both sample size and acceptance rule to be determined, starting from a specific value either for the consumer or producer risk. However, insufficient resources often make it difficult to implement “ISO sampling plans.” In cases where the sample size is determined by external constraints, the focus shifts from determining sample size to determining consumer and producer risks. Moreover, if the sample size is very low (e.g. one single item), prior information should be included in the statistical analysis. For this reason, it makes sense to work within a Bayesian theoretical framework, such as that described in JCGM 106. Accordingly, the approach from JCGM 106 is adopted and broadened so as to allow application to lot inspection. The discussion is based on a “real-life” example of lot inspection on the basis of a single item. Starting from simple assumptions, expressions for both the prior and posterior distributions are worked out, and it is shown how the concepts from JCGM 106 can be reinterpreted in the context of lot inspection. Conceptual differences regarding the definition of consumer and producer risks in JCGM 106 and in the ISO acceptance sampling standards are elucidated and a numerical example is provided.

In recent years, data providers are generating and streaming a large number of images. More particularly, processing images that contain faces have received great attention due to its numerous applications, such as entertainment and social media apps. The enormous amount of images shared on these applications presents serious challenges and requires massive computing resources to ensure efficient data processing. However, images are subject to a wide range of distortions in real application scenarios during the processing, transmission, sharing, or combination of many factors. So, there is a need to guarantee acceptable delivery content, even though some distorted images do not have access to their original version. In this paper, we present a framework developed to estimate the images' quality while processing a large number of images in real-time. Our quality evaluation is measured using an integration of a deep network with random forests. In addition, a face alignment metric is used to assess the facial features. Experimental results have been conducted on two artificially distorted benchmark datasets, LIVE and TID2013. We show that our proposed approach outperforms the state-of-art methods, having a Pearson Correlation Coefficient (PCC) and Spearman Rank Order Correlation Correlation Coefficient (SROCC) with subjective human scores of almost 0.942 and 0.931 while minimizing the processing time from 4.8ms to 1.8ms.

There is a systematic exclusion of gender-based violence, safe abortion, reproductive cancers, infertility services, comprehensive sexuality education, sexuality services, and STI’s other than HIV in essential health packages in LMICs. To accelerate progress on sexual reproductive health (SRH), the Guttmacher–Lancet Commission proposed the adoption of these interventions into an essential health package of SRH services that should be universally available. In this commentary, we use a healthcare priority-setting processes lens to review the importance of these services for universal health coverage. We isolate inherent challenges in social value judgments for terminal, process and content evidence for their healthcare priority-setting. We then advance promising emerging practical examples from low to middle-income countries on evidence-informed decision-making processes. We recommend capacity development through regional support, generating equity and efficiency evidence and strengthening political and publicly acceptable processes to institutionalise and operationalise evidence-informed decision-making.

C-reactive protein (CRP) and leukocytes are blood biomarkers involved in "Inflamm-Aging", which is a risk factor for the onset and progression of age-related diseases. Studies show that higher serum concentrations of these biomarkers are associated with functional disability, increased risk of low muscle strength, decreased muscle mass and mortality in the elderly. The objective was to estimate the predictive power and discriminating criteria of C-reactive protein and leukocyte concentrations for the risk of adverse health factors in the elderly within 30 days after hospital discharge (HD). Prospective cohort study using exploratory methods and blood biomarkers with 135 older adults admitted to medical and surgical clinics at a government hospital. The elderly were monitored at home after 30 days of HD for adverse health factors (rehospitalization, falls, amount of medication consumed, disability in basic and instrumental activities of daily living and mortality). CRP> 2.4; ≥ 0.7 and> 24.7 mg / dL and leukocytes ≥ 6.410; ≥ 8.690 and> 8.310 mm³ were discriminant for rehospitalization, falls and mortality within 30 days after HD, respectively. The cut-off points described may be used as a reference in the screening of hospitalized elderly vulnerable to adverse health events after hospital discharge.

Currently, the most important challenge in any assessment of state-of-the-art sensor technology and its reliability is to achieve road traffic safety targets. The research reported in this paper is focused on the design of a procedure for evaluating the reliability of Internet-of-Things (IoT) sensors and the use of a Cyber-Physical System (CPS) for the implementation of that evaluation procedure to gauge reliability. An important requirement for the generation of real critical situations under safety conditions is the capability of managing a co-simulation environment, in which both real and virtual data sensory information can be processed. An IoT case study that consists of a LiDAR-based collaborative map is then proposed, in which both real and virtual computing nodes with their corresponding sensors exchange information. Specifically, the sensor chosen for this study is a Ibeo Lux 4-layer LiDAR sensor with IoT added capabilities. Implementation is through an artificial-intelligence-based modeling library for sensor data-prediction error, at a local level, and a self-learning-based decision-making model supported on a Q-learning method, at a global level. Its aim is to determine the best model behavior and to trigger the updating procedure, if required. Finally, an experimental evaluation of this framework is also performed using simulated and real data

Mediterranean climate is marked by arid climate conditions in summer, therefore, crop irrigation is crucial to sustain plant growth and productivity in this season. If groundwater is utilized for irrigation, an impressive water pumping is needed to satisfy crop water requirements at catchment scale. Consequently, irrigation water quality gets worse, specifically considering groundwater salinization near the coastal areas due to seawater intrusion, also triggering soil salinization. With reference to an agricultural coastal area in the Mediterranean basin (Southern Italy), close to the Adriatic sea, an assessment of soil salinization risk due to processing tomato cultivation was carried out. A simulation model was arranged to perform, on daily basis, a water and salt balance along the soil profile. Long-term weather data and soil physical parameters representative of the considered area were utilized in applying the model, also considering three salinity levels of irrigation water. Based on the climatic analysis performed and the model outputs, the probability of soil salinity came out very high, such as to seriously threaten tomato yield. Autumn-winter rainfall resulted frequently insufficient to leach excess salts away from the soil profile and reach sustainable conditions of tomato cultivation. Therefore, alternative cropping strategies were prospected.

This paper presents the methods of estimating the mean square error of hydrological forecasts, allowing for assessment of their practical applicability. Depending upon the amount and composition of available hydrometeorological data, an appropriate method for forecast error estimation is chosen. A system of statistical tests for comparison of different forecasting methods for the same hydrologic characteristic with the same lead time is presented. These tests allow for choosing an optimal and most accurate forecasting method. Hydrological forecasting method efficiency estimation is based on comparing the forecast error with climatology or inertial (persistence) forecast error using presented tests.

Abstract: The frequency and intensity of air pollution are two of most critical issues the world faces in dealing with global environmental problems. They are both important areas that need to be improved. Our previous research [20] examines the assessment of fine dust pollution in Baekryeong island by statistical reasoning through one specific example of inland city (Yanggu) in Republic of Korea; however, given that Baekryeong Island is a remote island, there has been little focus on in-depth examination of its effect on the high density of fine dust in Baekryeong Island. The purpose of this article is twofold: (i) to examine the effect of a remote island on the high density of fine dust on Baekryeong Island using statistical reasoning and to provide a more specific statistical basis for the claim that one of the non-negligible factors influencing the high density of fine dust on Baekryeong Island is the geographic proximity to China; and (ii) to present brief discussion of fundamental cause of fine dust and global air pollution issues, which are not discussed in [20].

Major marine construction projects, resulting in the release of sediments, are subject to environmental assessment and other regulatory approval processes. An important tool used for this is the development of specialized numerical methods for these marine activities. An integrated set of numerical methods addresses four distinct topics: the near-field release and mixing of suspended sediments into the water column (i.e. the initial dilution zone); the transport of the suspended sediments under the influence of complex ocean currents in the far-field; the settling of the transported suspended sediments onto the seabed; and the potential for resuspension of the deposited sediments due to sporadic occurrences of unusually large near-bottom currents. A review of projects subjected to environmental assessment in the coastal waters of British Columbia from the year 2006 to 2017, is presented to illustrate the numerical models being used and their ongoing development. Improvements include higher resolution model grids to better represent the near-field, the depiction of particle size dependent vertical settling rates and the computation of resuspension of initially deposited sediments, especially in relation to temporary subsea piles of sediments arising from trenching for marine pipelines. The ongoing challenges for this numerical modeling application area are also identified.

This study explores the use of Generative Artificial Intelligence (GAI) in assessing pilot fatigue risk by integrating facial recognition and physiological signals with Inertial Measurement Units (IMUs). By leveraging IMU technology's precise, real-time data on movement and combining it with GAI's advanced data analysis capabilities, the study aims to enhance the accuracy of fatigue prediction models. The analysis reveals that while traditional classifiers like Extreme Random Trees and Random Forests offer modest performance, advanced models such as Support Vector Machines and Naive Bayes demonstrate superior recall rates, highlighting their potential to identify true positives. This integration of AI and IMUs offers a promising approach to developing comprehensive, real-time fatigue monitoring systems, improving safety and efficiency in aviation by providing actionable insights and facilitating more effective fatigue management.

Background/Objectives: Catastrophization and other comorbid psychological factors that increase awareness of pain are known to hinder chronic pain recovery. Five pilot studies, reported here, indicate that increased pain awareness from frequent pain assessment may impede chronic pain recovery through similar mechanisms. Methods: All study participants were asked to use a biofeedback device at least twice daily. Studies 1 and 2 required pain assessment before and after each biofeedback session, while Studies 3-5 did not. Pain levels were measured by the McGill Pain Inventory (McGill PI) at the start and end of each study. Results: Studies 3-5 replicated our prior work, demonstrating changes in pain, anxiety, and satisfaction and recovery following a home-use biofeedback program. Participants in the studies without frequent pain assessment experienced greater overall reductions in pain compared to participants in studies that did not require pain assessment. The results are, however, statistically inconclusive due to high variability, so further research is necessary. Conclusion: The results of our study suggest that frequent pain assessment may hinder pain reduction, likely by facilitating negative thought patterns and neural circuits involved in chronic pain. These findings can be applied to developing better research designs and more effective chronic pain recovery programs.

Background: Pharmacists need up-to-date knowledge and decision-making support in HIV care. We aim to develop MARVIN-Pharma, an adapted artificial intelligence-based chatbot initially for people with HIV, to assist pharmacists, considering evidence-based needs. Methods: From Dec 2022 to Dec 2023, an online needs-assessment survey evaluated Québec pharmacists' knowledge, attitudes, involvement, and barriers relative to HIV care, alongside perceptions relevant to the usability of MARVIN-Pharma. Recruitment involved convenience and snowball sampling, targeting National HIV and Hepatitis Mentoring Program affiliates. Results: Forty-one pharmacists (28 community, 13 hospital-based) across 15 Québec municipalities participated. Participants perceived their HIV knowledge as moderate (M=3.74/6). They held largely favorable attitudes towards providing HIV care (M=4.02/6). They reported a “little” involvement in the delivery of HIV care services (M=2.08/5), most often ART adherence counseling, refilling, and monitoring. The most common barriers reported to HIV care delivery were a lack of time, staff resources, clinical tools, and HIV information/training, with pharmacists at least somewhat agreeing that they experienced each (M≥4.00/6). On average, MARVIN-Pharma's acceptability and compatibility were in the ‘undecided’ range (M=4.34, M=4.13/7, respectively), while pharmacists agreed to their self-efficacy to use online health services (M=5.6/7). Conclusion: MARVIN-Pharma might help address pharmacists' knowledge gaps and barriers to HIV treatment and care, but pharmacist engagement in the chatbot’s development seems vital for its future uptake and usability.

China is facing the development requirements of the dual carbon goal and the construction needs of resilient cities. Currently, high-strength composite structural systems are a feasible solution, but their research and application in the construction field are insufficient, especially for the combination forms of concrete above C100 and steel above Q550. In response to this issue, this paper proposes a new high-performance structural system, namely the composite frame - high-strength steel plate wall core tube resilient structure system, which includes high-strength steel plate (Q550) - ultra-high strength concrete (C100) shear walls, replaceable energy dissipation coupling beams, and composite frames. Taking a 200 meter building as an example, this paper designs and establishes calculation models for a conventional reinforced concrete frame-core tube structure and a high-performance structure based on PKPM software, and establishes elastoplastic analysis models for both based on SAUSAGE software, and then conducts dynamic elastoplastic time history analysis and seismic resilience assessment of structures under design basis earthquakes (DBEs), maximum considered earthquake (MCEs) and extremely rare earthquakes (EREs). Research has shown that compared to conventional structures, new high-performance structures can effectively reduce the size of shear walls, reduce the self-weight of the structure, and enhance the space for building use; The story drift ratio has higher redundancy than specification limits, lower plastic damage and overall stiffness degradation of the structure, and better seismic performance; The seismic resilience has significantly improved, especially in the case of casualties, which can better ensure the safety of people's lives and property.