Efforts to achieve carbon neutrality, which aims to reduce the net carbon emissions to zero by decreasing carbon emissions from human activities and increasing carbon absorption, are actively underway. Additionally, the search for clean energy alternatives to fossil fuels has become a global research trend. This paper presents research on metal-air batteries, focusing on the development of energy supply technologies that do not generate carbon emissions during power generation and require less space for power generation compared to existing renewable energy sources. The proposed Mg-Air Battery (MAB) in this study uses magnesium as the metal anode and theoretically offers a maximum open-circuit voltage of 3.1V and a high energy density of 6.8kWh/kg. While previous research has primarily focused on designing small-capacity cells and maximizing the performance of metal anodes, this study differentiates itself by designing a large-capacity MAB cell and optimizing its electrical performance. For the large-capacity cell design, the weight, shape, and size of the anode were designed based on MAB performance factors, and research was conducted on manufacturing methods to optimize the performance of the air cathode. Furthermore, to enhance usability and extend the lifespan of the MAB cell, it was designed to allow electrolyte circulation, and the electrolyte circulation performance was verified through simulations of fluid flow within the cell. Based on the study of the power performance of the newly designed large-capacity MAB cell, the feasibility of con-structing a kW-class system using multiple Mg-Air battery cell stacks was confirmed.

A study is reported on the electrochemical alloying-dealloying properties of Mg₂Sn intermetallic compounds. ¹¹⁹Sn Mössbauer spectra of β-Sn powder, thermally alloyed cubic-Mg₂Sn and an intermediate MgSn nominal composition are used as references. The discharge of a Mg/micro-Sn half-cell led to significant changes in spectra line shape that are explained by a multiphase mechanism involving the coexistence of c-Mg₂Sn, distorted Mg_2-δSn and Mg-doped β-Sn. Capacities and capacity retention were improved by using nanoparticulate tin electrodes. This material reduces significantly the diffusion lengths for magnesium and contains surface SnO and SnO₂, which are partially electroactive. The half-cell potentials were suitable to be combined versus MgMn₂O₄ cathodes. Energy density and cycling properties of the resulting full Mg-ion cells are also scrutinized.

Exploring effective oxygen reduction reaction (ORR) electrocatalysts is crucial for progress in solid-state alkaline zinc-air batteries (ZAB). In this paper, silver-manganese dioxide-carbon nanotubes (SMC) ternary composites, which function as Electrocatalyst for air Electrodes, was produced via the pyrolysis of silver permanganate under microwave irradiation in one step. A scanning electron microscope (SEM), X-ray diffraction (XRD), and an energy dispersion spectrometer (EDS) have consistently determined that SMC consists of silver and alpha-manganese dioxide, which anchored on the surface of CNTs. Through polarization and chronoamperometery curves, the electrocatalytic activity of SMC for ORR was examined. The results reveal that SMC has higher catalytic activity than the chemically produced electrocatalyst for ORR in alkaline condition. Finally, a solid-state zinc-air cell with an electrocatalyst was constructed and tested. Constant current discharge curve of the zinc-air cell with SMC has a long discharge voltage plateau and a 60.03 mAh capacity at 30 mA · cm−2 . The mechanism of improvement in electrocatalytic activity was also discussed. In a summary, the strategy described in this study and the electrocatalyst produced can be regarded as an effective method for making a robust oxygen reduction catalyst toward solid-state zinc-air batteries.

Lead-acid batteries utilised in electrical substations release hydrogen and oxygen when these are charged. These gases could be dangerous and cause a risk of fire if they are not properly ventilated. Therefore, this research seeks to design and implement a network control panel for heating, ventilation, and air-conditioning systems (HVACS). This is done using a specific range of controllers, which have more than thirty loops of proportional, integral and derivative (PID) control to achieve a cost-effective design. It performs the required function of extracting hydrogen, oxygen, and maintaining the desired temperature of the battery storage room within the recommended limits (i.e. 25°C ±1°C tolerance) without compromising quality as set out in the user requirement specification in Appendix-A. The system control panel allows the user to access control parameters such as changing temperature set-points, fan-speed, sensor database amongst others. The hardware is configured to detect extreme hydrogen and oxygen gas content in the battery room and ensure that the HVACS extract the gas content to the outside environment. The results of the system show that the network control panel effectively operates as per the recommended system requirements. Therefore, the effective operation of the HVACS ensures sufficient gas ventilation, thus mitigating the risk of fire in a typical battery storage room. Furthermore, the effective operation of HVACS enhances battery lifespan because of regulated operating temperature, which is conducive to minimise the effect of sulfation in lead acid Batteries (LABs).

Magnesium is a promising material. It has a remarkable mix of mechanical and biomedical properties that made it suitable for a vast range of applications. With alloying, many of these inherent properties can be further improved. Today, it is primarily used in the automotive, aerospace, and medical industry. However, magnesium has its own set of drawbacks which the industry and research community are actively addressing. Magnesium’s rapid corrosion is its most significant drawback, and it dramatically impeded magnesium’s growth and expansion into other applications. This article will review both the engineering and biomedical aspects and applications for magnesium and its alloys. It will also elaborate on the challenges the material faces, how they can be overcome, and its outlook.

The global context of research for new sustainable energy storage technologies makes it a very active sector with significant scientific and economic challenges. Indeed, due to the irregular development of renewable energies and the shutdown of traditional power facilities, it is difficult to maintain a stable balance in terms of supply and demand: energy storage can help in particular for substantial changes in the latter. Metal air batteries have a higher energy density and are safer than other available energy storage devices. Based on the existing and proven lead-acid battery technology, this paper proposed an open cell foam manufactured by the Excess Salt Replication process for use as an anode for lead-air battery cellsies with sulphuric acid as the electrolyte. This will save lead and reduce the battery weight. A 25% antimonial lead alloy was used to produce open cell foams with a cell diameter between 2 mm and 5 mm for the antimonial lead-air battery. Preliminary results of the effective electrical conductivity of self-discharged primary battery cells, measured experimentally, showed that all antimonial lead foam-air battery cellsies performed better than that made from the same dense non porous antimonial lead alloy. This is generally due to their important specific surface area where oxidation-reduction reactions took place. A correlation between the effective electrical conductivity and the cell diameter has been established and the highest conductivity was obtained with a cell diameter of 5mm. The feasibility of such an electrical system has been demonstrated.

New composite with core-shell structure based on magnesium hydride and finely dispersed aluminum powder with aluminum oxide shell was mechanically synthesized. We used magnesium chips to produce magnesium hydride and aluminum wire after exploitation to produce nano-sized aluminum powder. The beginning of the hydrogen release from composite occurred at the temperature of 117°C. The maximum desorption temperature from the MgH₂-EEWAl composite (10 wt.%) is 336°C compared to pure magnesium hydride – 417°C. The mass content of hydrogen in the composite is 5.5 wt.%. The positive effect of aluminum powder produced by the electric explosion of wires method on reducing the activation energy of desorption was demonstrated. Calculations showed that the activation energy of desorption for the composite is 106±1 kJ/mol, compared with pure magnesium hydride, whose activation energy was 155±2 kJ/mol. The results obtained make it possible to expand the possibility of using magnesium and aluminum waste for hydrogen energy.

Different inlet structures have a significant impact on the internal flow characteristics of a solid-magnesium powder water ramjet engine. Based on the magnesium-water reaction model, a computational fluid dynamics (CFD) method is applied to establish a numerical simulation method for the internal flow field of the engine, and the internal flow characteristics of the engine under different inlet structure conditions are studied. The simulation results show that high-temperature gas can effectively promote the ignition of magnesium powder at the top of the combustion chamber, while accelerating the evaporation of the first inlet water and increasing the combustion rate of magnesium powder. The secondary inlet has the most significant effect on the temperature inside the combustion chamber. When the secondary inlet flow rate increases towards the top of the combustion chamber, it increases the amount of heat absorbed by the evaporating water at the top of the chamber, thereby reducing the temperature at the top of the combustion chamber. However, when the flow rate is low, it results in insufficient oxidizer at the top of the combustion chamber, which is unfavorable for the combustion of magnesium powder.

Substituted bis(iminophosphoranyl)methanes are CH acidic compounds that can form complexes with formally dianionic central carbon centres. The reaction of H₂C(Ph₂P=NDip)₂ (≡ H₂L), Dip = 2,6-diisopropylphenyl, with one equivalent of di-n-butylmagnesium afforded the methanide complex [HLMgnBu] 1. Treatment of complex 1 with phenylsilane in aromatic solvents at elevated temperatures afforded the methanediide complex [(LMg)₂] 2 presumably via the MgH intermediate [(HLMgH)_n] (n = 1 or 2). The reaction of 1 with LiAlH₄ in diethyl ether yielded the AlH complex [HLAlH₂] 3. Alternatively, this complex was also obtained from the reaction of H₂L with AlH₃∙NMe₃. The molecular structures of [HLMgnBu] 1, [(LMg)₂] 2, and [HLAlH₂] 3 are reported. Complex 3 shows no sign of H₂ elimination to a methanediide species at elevated temperatures in contrast to the facile elimination of the putative reaction intermediate [(HLMgH)_n] (n = 1 or 2) to form [(LMg)₂] 2. The chemical properties of complex 2 were investigated and this complex appears to be stable against coordination with strong donor molecules.

Biomedical devices made from high-modulus and hardness materials play a critical role in enhancing the quality of life for individuals with bone-related ailments. While these materials have been successfully used in orthopedic applications, concerns including stress-shielding have necessitated the exploration of alternative solutions. An ideal biomedical implant requires a delicate balance of mechanical performance, corrosion resistance, tissue biocompatibility, and other properties such as tribological performance and osseointegration. This review explores the suitability of biodegradable magnesium (Mg) alloys as a promising material for biomedical implants. It delves into the essential properties of biomedical implants, emphasizing the importance of matching mechanical characteristics with human bone properties to mitigate stress shielding. The corrosion properties of implant materials are discussed, highlighting the need for controlled degradation to ensure the safety and longevity of implants. The focus then shifts to the potential of magnesium alloys as biomedical implants, examining their benefits, limitations, and the challenges associated with their high degradation rates and less-than-satisfactory mechanical properties. Alloying with elements such as aluminum, zinc, and others is explored to improve magnesium alloys' mechanical performance and corrosion resistance. Furthermore, this review discusses surface modification techniques, including chemical conversion coatings and biomimetic deposition, as effective strategies to enhance the corrosion resistance and biocompatibility of magnesium and its alloys. These modifications offer opportunities to improve the long-term performance of magnesium-based biomedical implants. This paper provides a comprehensive overview of the properties, challenges, and potential solutions associated with biodegradable magnesium alloys as a promising material for biomedical implants. It underscores the importance of addressing issues related to mechanical performance, corrosion resistance, and biocompatibility to advance the development of safe and effective biomedical implant materials.

The growing demands of material longevity in marine environments necessitate the development of highly efficient, low-cost and durable corrosion protective coatings. Although magnesium alloys are widely used in the automotive and aerospace industries, severe corrosion issues still hinder their long-term service in naval architecture. In present work, an epoxy composite coating containing sericite nanosheets is prepared on the AZ31B Mg alloy by one-step electrophoretic deposition method to improve corrosion resistance. Due to the PEI modification, positively-charged sericite nanosheets can be highly orientated in an epoxy coating under the influence of an electric field. The sericite-incorporated epoxy coating prepared in the emulsion with 4 wt.% sericite exhibits the highest corrosion resistance in 3.5 wt.% NaCl solution, as manifested by electrochemical corrosion and long-term immersion tests. The highly-orientated sericite nanosheets in epoxy coating provide excellent barrier effect against corrosive media, thereby significantly improving the long-term anti-corrosion performance of the epoxy coating. This work provides new insight toward the design of lamellar filler/epoxy coatings with superior anticorrosion performance and shows promise in the corrosion protection of magnesium alloys.

The synthesis of chelating NHC complexes with considerable π-acceptor properties can be a challenging task. This is due to the dimerization of free carbene ligands, the moisture sensitivity of reaction intermediates or reagents, and challenges associated with the workup procedure. Herein, we report a general route using transmetalation from magnesium NHCs. Notably, this route gives transition metal complexes in quantitative conversion without the formation of byproducts. Accordingly, it allows for the facile access to transition metal complexes where the conventional routes via the free or lithium coordinate carbene, the silver complexes, or in situ metalation in dimethyl sulfoxide (DMSO) fail. We therefore propose transmetalation from magnesium NHCs as a convenient and general route to NHC complexes.

Bisphosphonates (BPs) are successfully used to cure a number of bone diseases characterized by metabolic osteopenia, such as Osteoporosis, or neoplastic osteolysis, such as Multiple Myeloma and Bone Metastases. These drugs exert their therapeutic effect inducing a systemic osteoclast depletion that, in turn, is responsible for a reduced bone resorption. Unfortunately, in addition to their beneficial activity, BPs can also determine a frightening side effect known as Osteonecrosis of the Jaw (ONJ). It is generally believed that the inability of osteoclasts to get rid of inflamed / necrotic bone tissue represents the main physio-pathological aspect of ONJ. In principle, a therapeutic strategy able to elicit a local re-activation of osteoclast production could counteract ONJ and promote the healing of its lesions. We have previously demonstrated that Magnesium (Mg) is a powerful inducer of osteoclast differentiation. Using a model of Vitamin D3 – dependent osteoclastogenesis, based on the U937 cell line, here we show that, surprisingly, this property of Mg is greatly enhanced by the presence of Zoledronic Acid (ZA), chosen for our study because it is the most effective among BPs. This finding allow us to hypothesize that Mg might play an important role in the topical therapy of ONJ.

Long Covid (LC), Chronic Fatigue Syndrome (CFS), Postural Orthostatic Tachycardia Syndrome (POTS), Mast Cell Activation Syndrome (MCAS), Small Intestine Bacterial Overgrowth (SIBO), and Ehlers-Danlos Syndrome (EDS) are all loosely connected, some poorly defined, some with overlapping symptoms. The female preponderance, the prominence of fatigue and chronic inflammation, and methylenetetrahydrofolate reductase (MTHFR) abnormalities may connect them all. Indeed differential methylation may lie at the root. Two - EDS and MTHFR - are genetic. But epigenetic factors may ultimately determine their phenotypic expression. Oxidative stress, overloaded mitochondria, an antioxidant and nutrient shortfall, and suboptimal gut microbiome appear to be the primary determinants. A deep dive into the folate and methionine cycles is undertaken in an attempt to connect these syndromes. The active forms of vitamin D and vitamins B2,3,6,9,12 are shown to be biochemically integral to optimal methylation and control of the epigenome. Their status largely determines the symptoms of abnormal MTHFR in all its phenotypes. The wider implications for aging, cancer, cardiovascular disease, neurodegenerative disease, and autoimmune disease are briefly explored.

Evidence supports an association between low magnesium (Mg) intake and coronary heart disease and between Mg intake and endothelial function. The aim of this study was to assess the effect of one week of Mg supplementation on endothelial function, assessed by flow mediated dilatation (FMD). Nineteen healthy men and women completed this cross-over pilot study in which participants were randomised to take an over-the-counter magnesium supplement for one week or to follow their usual diet. Weight, FMD and blood pressure (BP) were taken on completion of each intervention and 24hour urine collections and blood samples were taken to assess compliance. Baseline serum Mg was within normal range for all participants. Urinary Mg and urinary magnesium-creatinine ratio (Mg/Cr) significantly increased between interventions, (p = 0.03, p = 0.005 respectively). No significant differences in FMD or BP were found between the interventions. A significant negative correlation was seen between age and FMD (r = -0.496, p = 0.031). When adjusted for age, saturated fat was negatively associated with FMD (p = 0.045). One week of Mg supplementation did not improve FMD in a healthy population.

Evidence supports an association between low magnesium (Mg) intake and coronary heart disease and between Mg intake and endothelial function. The aim of this study was to assess the effect of one week of Mg supplementation on endothelial function, assessed by flow mediated dilatation (FMD). Nineteen healthy men and women completed this cross-over pilot study in which participants were randomised to take an over-the-counter magnesium supplement for one week or to follow their usual diet. Weight, FMD and blood pressure (BP) were taken on completion of each intervention and 24hour urine collections and blood samples were taken to assess compliance. Baseline serum Mg was within normal range for all participants. Urinary Mg and urinary magnesium-creatinine ratio (Mg/Cr) significantly increased between interventions, (p = 0.03, p = 0.005 respectively). No significant differences in FMD or BP were found between the interventions. A significant negative correlation was seen between age and FMD (r = -0.496, p = 0.031). When adjusted for age, saturated fat was negatively associated with FMD (p = 0.045). One week of Mg supplementation did not improve FMD in a healthy population.

Magnesium (Mg) deficiency may be a catalyst in the process of endothelial dysfunction, an early event in the pathogenesis of atherosclerosis. The aim was to determine the acute effect of an oral Mg supplement compared to control on endothelieal function assessed by flow-mediated-dilatation (FMD). Nineteen participants (39 years, body mass index (BMI) 22.9kg/m2) completed this randomised cross-over study. Blood pressure (BP) and FMD were measured and blood samples taken before participants drank 200ml water with or without an over the counter Mg supplement (450mg and 300mg for men and women). Measurements were repeated at 60 and 120 minutes. There was a statistically significant two-way interaction between treatment and time on serum Mg (p = .037). A difference of -0.085mm in FMD was observed 60 minutes post drink in the control group compared to baseline FMD, and no difference was observed in the supplement group compared to baseline. Despite the non-significant interaction between treatment and time on FMD, the difference seen in the control group and the lack of change in the supplement group at 60 minutes post-drink suggests that Mg may attenuate the reduction in FMD post-prandially.

Monitoring and measuring magnesium (Mg) values are essential to prevent the development of numerous complications in perioperative medicine and critically ill patients. Although previous studies suggest that measuring free ionized magnesium (iMg) is more useful for estimating Mg status, clinicians currently rely on measurement of total serum magnesium to determine if supplemental magnesium is needed. In this review, we analyzed the recent literature to decide whether it is better to measure ionized serum Mg or total serum Mg when assessing magnesium status, whether iMg predicts clinical outcome, and what are the difficulties in measuring serum iMg levels in intensive care patients and perioperative medicine.

Urban air quality is increasingly becoming a cause for concern for the health of the human population. The poor air quality is already wreaking havoc in major cities of the world, where serious health issues and reduction of average human life by a factor of years are reported. The air quality in developing countries can become worse as they undergo development. The urban air quality varies non-linearly depending upon the various factors such as land use, industrialization, waste disposal, traffic volume, etc. To address this problem, it is necessary to look at the plethora of available literature from multiple perspectives such as types and sources of pollutants, meteorology, urban mobility, urban planning and development, health care, economics, etc. In this paper, we provide a comprehensive survey of the state-of-the-art in urban air quality. We first review the fundamental background on air quality and present the emerging landscape of urban air quality. We then explore the available literature from multiple urban air quality measurement projects and provides the insights uncovered in them. We then take a look at the sources that are significantly contributing to polluting the air quality. Finally, we highlight open issues and research challenges in dealing with urban air pollution.

Magnesium-doped hydroxyapatite (Mg-HAp) nanofibers show promise for medical applications due to their structural similarity to bone mineral and enhanced biological properties, such as improved biocompatibility and antimicrobial activity. This study synthesized Mg-HAp nanofibers using a microwave-assisted hydrothermal method (MAHM) to evaluate their cytotoxicity, biocompatibility, and antimicrobial efficacy compared to commercial hydroxyapatite (HAp). Characterization through X-ray diffraction (XRD), Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Energy Dispersive X-ray Spectroscopy (EDS), and Fourier Transform Infrared Spectroscopy (FTIR) confirmed the successful incorporation of magnesium, producing high-purity, crystalline nanofibers with hexagonal morphology. Rietveld refinement showed slight lattice parameter shortening, indicating Mg2+ ion integration. Cell viability assays (MTT and AlamarBlue) revealed a significant increase in fibroblast proliferation with 2% and 5% Mg-HAp concentrations compared to controls (p<0.05), demonstrating non-cytotoxicity and enhanced biocompatibility. Antimicrobial tests (disk diffusion method, 100 µg/ml) showed that Mg-HAp had strong antibacterial effects against Gram-positive and Gram-negative bacteria, and moderate antifungal activity against Candida albicans. In contrast, commercial HAp showed no antimicrobial effects. These results suggest Mg-HAp nanofibers have significant advantages as biomaterials for medical applications, particularly in preventing implant-related infections, supporting further clinical development.

Abstract Objective: To assess wound infiltration with ropivacaine plus magnesium sulfate for pain relief following thyroid surgery. Background: Analgesia with local anesthetics following surgery is a critical element of alleviating postoperative pain. However, such strategies in neck surgery has not been a well-established practice. Methods: This prospective double-blind randomized study enrolled 68 patients who underwent thyroid surgery. Concerning the solution used for surgical wound infiltration the study participants were randomly allocated into three groups: 1) 100 mg of ropivacaine (Group R), 2) 100mg of ropivacaine plus magnesium sulfate 10mg/kg (Group RMg), and 3) normal saline which served as placebo (Group P). Pain perception both at rest and at movement, was measured using the Visual Analogue Scale (VAS) at 30 minutes, as well as 1, 2, 4, 6, 12, and 24 hours postoperatively. The total consumption of analgesics in morphine equivalents was also recorded. Moreover, adverse effects and patient satisfaction were recorded. Cortisol, TNF-α, and IL-6 levels were measured 30 minutes before infiltration, 6 hours and 24 hours postoperatively. Results: Demographics and clinical characteristics were similar between the groups. The VAS scores at rest and during movement were significantly lower in the RMg group compared to saline or ropivacaine groups. Total analgesic consumption was also significantly lower in the RMg group. No operational, wound or infiltration-related adverse effects were recorded in the study groups. Better overall satisfaction was obtained for the group RMg. Conclusions: Ropivacaine plus magnesium sulfate wound infiltration provided better pain control and analgesic effect was more significant, contributing to effective postoperative analgesia in patients undergoing thyroid surgery.

Brain fog with compromised ability to concentrate has been the most frequent Long Covid (LC) complaint. This is due to an increased transforming growth factor (TGF) β/interferon (IFN)-γ ratio with consequently increased bradykinin (BKN), especially in Caucasian females. Brain and lung blood vessels “leak.” This same ratio is increased in Alzheimer’s disease (AD), but decreased in Parkinson’s disease (PD), because CD4⁺ and CD8⁺ T cells are differentially affected by the invading associated viruses, e.g., SARS CoV2, HIV, Varicella Zoster (VZV) aka Human Herpesvirus 3 (HHV3), HBV, HCV, …. In Covid-19 CD147 receptors on immune cells are critical in generating the increased TGF-β/IFN-γ and those on endothelial cells, platelets, and erythrocytes are critical to the abnormal microvascular blood flow. ACE2 receptors on pneumocytes and enterocytes enable pulmonary and GI entry, initiating gut dysbiosis. Epigenetics, methylation, magnesium, vitamin D, the B vitamins, and antioxidants suggest that these issues can be surmounted. Biochemical, physiologic, and epidemiologic data are analyzed to answer these questions. An LC model is presented and discussed in the context of the most recent research. Suggestions to avoid these and other worrisome concerns are included. Other topics discussed include estrogen, the gut microbiome, type 2 diabetes (T2D), and homocysteine.

(1) Background: Reduced magnesium (Mg) levels may be associated with a faster de-cline in renal function. The aim of this study was to evaluate the association of serum and uri-nary Mg levels with body composition and inflammatory markers; (2) Methods: Lon-gitudinal study with patients with chronic kidney disease undergoing non-dialysis treatment in stages 3A, 3B and 4. Venous samples were collected after a 12-hour night fast. Body composition was evaluated by Double X-Ray Emission Absorptiometry and Air Displacement Plethysmog-raphy; (3) Results: The sample consisted of 134 patients. In the adjusted linear regression model, uric acid, percentage of lean mass and ali-mentar intake of Mg were positively associated with the sergic Mg. Triglyceride levels, WC and fat mass percentage were negatively associated with serum Mg. For the Mg urinal, in the adjusted model, the eGFR (estimated glomerular filtration rate), IL (interleukin 6), food intake of Mg and the percentage of lean mass showed a positive correlation.; (4) Conclusions: Serum Mg levels were positively associated with lean mass and negatively with total and central body fat and urinary Mg was positively associated with IL6 and lean mass.

The aim of the present study was to measure the apparent absorption of magnesium (Mg) originating from Mg-butyrate. Six mid-lactation Holstein Friesian dairy cows were used with dietary treatments arranged in a cross-over design. Two different diets were fed during the experiment, consisting of a low Mg diet without Mg-butyrate (L-Mg, 3.1g Mg/kg dry matter) or a high Mg diet with Mg-butyrate (H-Mg, 3.9 g Mg/kg dry matter). Cows offered the L-Mg diet ingested 54.7 g Mg/day while the cows fed the H-Mg diets ingested 66.3 g Mg/day (P < 0.001). The fecal excretion of Mg, however, was similar between the two experimental diets (P = 0.174). Consequently, apparent Mg absorption was found to be 7.9 percentage units greater (P = 0.038) when the cows were fed the diet supplemented with Mg-butyrate. The greater Mg absorption after feeding the H-Mg diet was, however, not reflected by a greater urinary Mg concentration (P = 0.228). These results indicate that the availability of Mg from the Mg-butyrate supplemented diet is high (34.1% of intake). The fractional Mg absorption from Mg-butyrate was calculated to be 71.6%. In conclusion, Mg-butyrate is an attractive alternative to supplement dairy rations with Mg.

Although the dry ice method used to synthesize exfoliated graphite/graphene is little known and used, it has significant advantages over others: it is low cost, simple, and a large quantity of material can be obtained using some inorganic and highly available acids (which can be reused). Despite the above advantages, the main reason for its incipient development is the resulting presence of magnesium oxide in the final product. In the present work, three different treat-ments were tested to remove this remnant using some acid chemical leaching processes, making use of hydrochloric acid, aqua regia, and piranha solution. Based on the experimental evidence, it was found that using aqua regia and combining the leaching process with mechanical milling was the most efficient way of removing such a remnant, the residue being only 0.9 wt.%. This value is low when compared to that obtained with the other acid leaching solutions and purifi-cation process (2.8 - 29.6 wt.%). A mandatory high-energy mechanical milling stage was neces-sary during this treatment, in order to expose and dissolve the highly insoluble oxide without secondary chemical reactions on the graphenes. High-energy mechanical milling is an effective route to exfoliate graphite/graphene, which allows the magnesium oxide to be more susceptible to acid treatment. The obtained surface area was 504 m2g-1; this high value resulting from the in-tense exfoliation can potentiate the use of this material for a wide variety of applications.

Revealing the binding properties of calcium ion (Ca2+) and magnesium ion (Mg2+) to chromophoric dissolved organic matter (CDOM) facilities understanding the effect of natural water composition on the photophysics of dissolved organic matter. Steady-state and time-resolved fluorescence spectrometry, and dynamic light scattering were applied to investigate the fluorescence quenching process of CODM by Ca2+ and Mg2+. The binding of Ca2+ and Mg2+ preferred terrestrial CDOM to aquatic CDOM. The fluorescence quenching of CDOM by cations mainly occurred in a static process, which was based on the fact that the decrease of steady-state fluorescence intensity was greater than fluorescence lifetime. The fluorescence quenching was profound under longer excitation and emission wavelength. The binding constant (K, L/mol) for Ca2+ to CDOM from terrestrial source ranged from 4.29 to 5.09 (lgK), which was approximately one order of magnitude higher than that of Mg2+ to CDOM (3.86 to 4.56). Fluorescence decay became faster in the presence of Ca2+ and Mg2+. Lifetime distribution of CDOM excited states shifted to small value side in the presence of metal ions, particularly for Ca2+, indicating fluorescence quenching of CDOM mainly through the interaction of Ca2+/Mg2+ with relatively long-lived fluorophores.

The present study investigated the effects of alloying and nano-reinforcement on the mechanical properties (microhardness, tensile strength, and compressive strength) of Mg-based alloys and composites. Pure Mg, Mg-3Sn alloy, and Mg-3Sn+0.2GNP alloy-nanocomposite were synthesized by powder metallurgy followed by hot extrusion. The microstructural characteristics of the bulk extruded samples were explored using X-ray diffraction, field-emission scanning electron microscopy, and optical microscopy and their mechanical properties were compared. The microhardness, tensile strength, and compressive strength of the Mg-3Sn alloy improved when compared to those of monolithic Mg sample and further improvements were displayed by Mg-3Sn+0.2GNP alloy-nanocomposite. No significant change in the compressive strain to failure was observed in both the alloy and the alloy-nanocomposite with respect to that of the pure Mg sample. However, an enhanced tensile strain to failure was displayed by both the alloy and the alloy-nanocomposite.

Magnesium supplementation has recently attracted attention as effective in the management of diabetes and its related complications though its mechanisms of action is yet to be fully unraveled. This study was carried out to determine the effects of magnesium supplementation on body weight, fasting blood sugar, Oral glucose tolerance (OGTT 2 and OGTT 4), glucose transporter isoform 2 (GLUT2), GLUT4 and insulin receptor (INSR) mRNA expressions in streptozotocin-nicotinamide induced diabetic Sprague dawley rats. A total of 24 Sprague dawley rats (Four groups of six rats each) were used for this study, and the treatment was for 28 days. Group 1: Normal control rats were given distilled water; Group 2: Metformin treated rats were given 100 mg/kg body weight; Group 3: Metformin + Magnesium treated rats were given 100 mg/kg and 1000 mg/kg body weight respectively; Group 4: Diabetic untreated rats given distilled water. Data were analyzed statistically using Analysis of Variance (ANOVA) and graphically by Graph pad prism. The GLUT4 and INSR gene expressions of Group 3 were significantly (p<0.05) upregulated when compared with Group 4. There was significant (p<0.05) decrease fasting blood sugar and GLUT2 mRNA level in the treated diabetic rats but the metformin-magnesium supplement treated group showed more decrease (p<0.05) when compared with the group treated with metformin only. This study demonstrates that magnesium may mediate effective metabolic control by stimulating insulin sensitivity, and upregulating mRNA levels of GLUT4, INSR as well as improving glucose tolerance in diabetic rats. Therefore, magnesium supplementation appears to have a beneficial role and improves glucose uptake by cells in those at high risks of diabetes. Magnesium supplementation, Metformin, INSR, GLU4, glucose tolerance.

Carrying out technological tests and research is indispensably connected with high costs and elongation of implementation time of new casting technologies and their modifications in industry. Hence, the application of specialised computer software, enabling the simulation and analysis of metallurgical and casting processes in modern foundry industry is of special interest. The present work presents an experimental application of MAGMASoft software in casting process of EV31A magnesium alloy structural element of helicopter engine. The results of computer simulation have been compared with industrial cast of the simulated element, fabricated in the same conditions. It has been revealed that the computer simulation provides a complex information on the analysed process, leading to reduction of costs and time, connected with technological tests in implementation of new casting technologies.

The automotive industry is continuously seeking innovative solutions to improve the energy efficiency and sustainability of vehicles. Among the various energy-consuming systems in automobiles, air conditioning plays a crucial role. However, conventional vapour compression-based air conditioning systems are known for their high energy consumption and environmental impact. In recent years, adsorption technology has gained significant attention as a promising alternative due to its potential for higher energy efficiency and reduced greenhouse gas emissions. This review paper presents a comprehensive analysis of advancements in adsorption air conditioning technology specifically designed for automotive applications. The paper examines the recent research and development efforts in enhancing the performance and practicality of these systems, encompassing areas such as advanced materials selection, and system integration strategies. Furthermore, this review highlights the benefits and challenges associated with implementing adsorption air conditioning systems in vehicles. The environmental impact and potential for waste heat recovery are also discussed. Additionally, emerging trends, such as hybridization with conventional vapour compression systems, are explored to further optimize the energy efficiency and sustainability of automotive air conditioning. By critically evaluating the existing literature and research advancements, this review provides insights into the state-of-the-art thermally driven technologies for automotive applications.

Lithium has long been recognized for its therapeutic efficacy in the treatment of manic-depressive illness (MDI). Additionally, numerous reports highlight its protective properties against cell insults, with a remarkable majority of these effects documented in neurons. Utilizing the major mechanisms of its action, we bring insights that explain lithium's ability to preferentially promote survival in neurons. Specifically, we explore its interactions with magnesium at protein binding sites, with a particular focus on its impact on glycogen synthase kinase 3 beta (GSK3β). We propose that lower intracellular free magnesium levels in the brain, coupled with the higher expression of GSK3β, which is an enzyme whose activity is magnesium-dependent, amplify its impact on brain cells, promoting neuronal survival.

Organic electrophoretic coatings have gained significant attention due to their ability to provide a uniform and controlled coating thickness, high coating adhesion, and excellent corrosion protection properties. In this work, to investigate the aging behaviors of an organic electrophoretic coating for magnesium alloys, water absorption kinetics curves of the coatings after immersion in 3.5 wt.% NaCl at 20℃ and 40℃ were measured, and parameters such as the saturated water absorption and saturation time of the free film coatings were fitted to determine the densification evolution of the organic coatings. A tensile test was used to test the tensile strength of the organic coating during service to determine the evolution of the strength and toughness of the organic coating. The evolution of wet adhesion of organic coatings with service time was tested by ASTM D4541-02. The impedance spectra of the organic coatings under the above conditions were detected by EIS, and finally, the failure behavior of the organic coatings under immersion was analyzed.

In order to establish the formation patterns of the Co–Mg oxide system, samples with different Co:Mg ratios and heat treatment temperatures were synthesized and studied. Study of the sam-ples confirmed the phase transition of MgxCo2–xO4 spinels into corresponding solid solutions at 800–900 °C. The similarity of formation patterns for different compositions is shown. The rock-salt oxide in low-temperature samples is an anion-modified paracrystalline phase that forms a “true” solid solution only upon spinel decomposition. TPR profiles of decomposed Co3O4 spinel show surface Co3O4 peaks and a wide peak corresponding to well-crystallized CoO, while par-tial Co3O4 TPR up to 380 °C results in dispersed and amorphous CoO. High-temperature non-stoichiometric samples are poorly reduced, indicating their low oxygen reactivity. Spinel reoxidation after heat treatment to 1100 °C by calcination at 750 °C showed complete regenera-tion for MgCo2O4–Co3O4 samples and its absence in case of an excess of MgO relative to stoi-chiometry. Based on the data obtained, it can be concluded that the processes governing the formation of Co–Mg oxide systems are determined by both Co:Mg ratio and the heat treatment conditions, potentially providing the possibility of fine tuning for specific catalytic processes.

These three syndromes - long covid (LC), postural orthostatic tachycardia syndrome (POTS), and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) - have many symptoms in common. The common denominator remains elusive. The blood brain barrier (BBB) has been a barrier not only to microbes and toxins but also to understanding pathogenetic links. There are several areas within the brain that have no BBB. These are known as circumventricular organs (CVOs) and their location relative to CNS nuclei that direct autonomic and neuroendocrine functions is provocative in the quest for pathogenesis. In addition the majority afflicted with LC and ME/CFS appear to be those with two MTHFR polymorphisms, present in over 50% of Americans. These polymorphisms elevate homocysteine. When homocysteine is combined with CVOs, the fog of POTS and its paradox are lifted. POTS may represent the intersection of LC and ME/CFS in those with the MTHFR gene (hypermethylation or 677TT). The gut microbiomes of LC and ME/CFS, deficient in butyrates, GABA, and diversity, are then linked with MTHFR genotype 677TT. Reactivation of neurotropic EBV and VZV, due to loss of surveillance by CD4+/CD8+ T cells, is seen as secondary. The oxidative stress generated by homocysteine, loss of glutathione, low fiber diet, and persistent chronic inflammation exhaust available mitochondria and, assisted by BKN and estrogen, exacerbate all the elements of these post viral fatigue syndromes.

The content of magnesium ions (Mg2+) in drinking water is relatively high and the excessive Mg2+ ingestion may lead to pathological lesions in human body system. At present, the detection of Mg2+ still relies on costly devices or/and complex organic fluorescence probes. To solve this problem, this work proposed a NaBH4-mediated co-reduction strategy for the synthesis of glutathione-stabilized bimetallic AuAg nanoclusters (GSH@AuAg NCs) with recognition performance to Mg2+. The preparation of GSH@AuAg NCs was simple and rapid and could be performed at mild conditions. The reaction parameters and sampling orders were optimized to understand the formation mechanism of GSH@AuAg NCs. The GSH@AuAg NCs exhibited a sensitive “light-on” fluorescence response to Mg2+ due to the re-molding of the interfacial physicochemical environment following the Mg2+ coordination, which affected the surface charge transfer process, and thus led to a novel method for fluorescence detection of Mg2+ with admirable selectivity for Mg2+. The proposed method showed a detection limit of 0.2 μM, and its practical utility for the detection of Mg2+ in real sample of purified drinking water was also demonstrated, confirming its practicability in monitoring the Mg2+ concentration in drinking water.

The process of shock wave focusing can make the strength of shock waves be continuously accumulated and turned into detonation wave in Pulse Detonation Engine (PDE). However, its effective application needs the inlet jets be in high temperature and velocity, which is difficult to be satisfied under certain conditions. Therefore, in this paper, metal magnesium assisted detonation initiation is proposed and the effect of magnesium particle addition on the shock wave focusing process in a kerosene-fueled PDE with cavity configuration is investigated through numerical simulation. The result showed that when the temperature of the premixed fuel/air jets injected in opposite direction was set as 650 K, the collision of leading shock waves on the central axis was the main source of energy deposition and the shock wave focusing could make the detonation be initiated in the cavity. When the temperature of jets is reduced to 550 K, fuel ignition and detonation could not be achieved through shock wave focusing. Then adding metal magnesium particles into the combustor made the energy deposition be enhanced and the detonation be induced. The diffusion of metal particles can significantly change the structure, motion, merging and dissipation of vortices in the flow field. Generally, the shock wave focusing process is basically not affected with metal particles injection. Therefore, this method can be successfully employed for detonation initiation in the cavity when the fuel/air premixed jet temperature is not high for PDE.

The impact of nutrition on immunity is an intense area of research. Malnutrition is linked to a higher risk of microbial infections, while severe infections usually lead to a nutritional imbalance in affected patients. The nutritional status has an impact on the severity of the ongoing SARS-CoV-2 infection. Studies conducted on small numbers of patients have shown the benefits of maintaining optimal vitamin (B12 and D) and mineral (zinc and magnesium) balance in reducing the intensity of COVID-19. Although consuming a balanced diet with a healthy lifestyle is always desirable, the importance of such practice is even more meaningful during the COVID-19 pandemic. Keeping an optimal balance of vitamins and minerals through healthy dietary habits helps to maintain a robust immune system that is essential to combat invading microbial pathogens, including SARS-CoV-2.

The current study investigated the impacts of light quality and different levels of fertility on mineral nutrient concentrations in shoot and root tissues of Chinese kale (Brassica oleracea var. alboglabra). ‘Green Lance’ Chinese kale were grown under: 1) fluorescent/incandescent light; 2) 10% blue (447 ± 5 nm) / 90% red (627 ± 5 nm) LED light; 3) 20% blue / 80% red LED light; and 4) 40% blue / 60% red LED light as sole-source lighting at two different levels of fertility. All plants were harvested 30 d after seeding, and shoot and root tissues were analyzed for mineral nutrients. Lighting and fertility interacted to influence kale shoot and root mineral nutrient concentrations. Results indicate sole-source LED lighting used in production can impact mineral nutritional values of baby leafy greens now popular for the packaged market.

Magnesium hydroxide continuous coagulation process was used for treating simulated reactive orange wastewater in this study. Effects of mixing conditions and retention time on the coagulation performance and floc properties of magnesium hydroxide were based on the floc size distribution (FSD), zeta potential and floc morphology analysis. Floc formation and growth in different reactors were also discussed.The results showed that increasing rapid mixing speed led to a decrease in the final floc size. Floc formation process was mainly carried out in rapid mixer, rapid mixing speed of 300rpm was chosen according to zeta potential and removal efficiency. Reducing retention time caused relatively small floc size in all reactors. When influent flow is 30 L/h (retention time of 2min in rapid mixer), the average floc size reached 8.06μm in rapid mixer, through breakage and re-growth, the floc size remained stable in flocculation basin. After growth, the final floc size reached to 11.21μm in sedimentation tank. The removal efficiency of reactive orange is 89% in magnesium hydroxide coagulation process.

Resveratrol, because of its low solubility in water and its high membrane permeability, is collocated in the second class of the biopharmaceutical classification system, with limited bioavailability due to its dissolution rate. Solid dispersion of resveratrol supported on magnesium dihydroxide (RESV@MDH) was evaluated to improve solubility and increase bioavailability of resveratrol. Fluorimetric microscopy and granulometric analysis display three types of microparticles with similar size: type 1 that emitted preferably fluorescence at 463 nm (λ_ecc 358 nm), type 2 that emitted preferably fluorescence at 605 nm (λ_ecc 550 nm) andtype 3 that are non-fluorescent. Micronized pure resveratrol display only microparticles type 1 whereas type 3 are associated to pure magnesium dihydroxide. Dissolution test in simulated gastric environment resveratrol derived from RESV@MDH in comparison to resveratrol alone displayed better solubility. According to the biopharmaceutical classification, an increase of 3 fold of resveratrol bioavailabilitywas observed after oral administration of 50 mg/Kg of resveratrol of RESV@MDH in rabbits. We hypothesize that type 2 microparticles represent magnesium dihydroxide microparticles with a resveratrol shell and that they are responsible for the improved resveratrol solubility and bioavailability of RESV@MDH.

Accumulative roll bonding (ARB) is one of methods of severe plastic deformation which is relevant for industrial production of sheets. While mechanical properties of several magnesium alloys subjected to ARB process have been studied, the physical properties have been reported only for some magnesium alloys. These properties are influenced by the texture developed during the ARB process and the temperature load. In the presented contribution, we studied thermal diffusivity and thermal conductivity of an AZ31 magnesium alloy after 1 and 2 passes through the rolling mill. Thermal diffusivity was measured with the laser-flash method in the temperature range between 20 and 350 °C. Thermal conductivity depends on the number of rolling passes. The microstructure and texture of sheets are significant factors influencing the thermal properties.

Reducing the hardness of hard water is of great concern nowadays due to some adverse effects on water pipes, boilers and soap consumption. Using the method of biomineralization to precipitate calcium and magnesium ions to become carbonate minerals was one of the most important innovations for reducing the hardness of hard water. The present study sought to explore the physical and chemical conditions of carbonates bio-precipitation and the potential use of Bacillus licheniformis SRB2 strain (GenBank: KM884945.1) isolated from sludge sample of Moshui River (Shandong University of Science and Technology, Qingdao, China) in reducing the hardness of hard waters by the induction of carbonate minerals. In this study, B. licheniformis SRB2 strain was identified based on the morphological, biochemical and 16S rDNA gene sequence homology analysis. The carbonate minerals induced by B. licheniformis bacteria in the liquid culture medium with 3% NaCl and Mg/Ca molar ratio of 0, 6, 8, 10 and 12 were investigated. The culture medium was inoculated with the bacterial liquid seed was set as the experimental group and the other culture medium was inoculated with the same volume of distilled water was set as the control group. The mineral phases, micromorphologies, and crystal structures were analyzed using X-ray powder diffraction, scanning electron microscope, energy dispersive X-ray detector, high resolution transmission electron microscopy and selected area electron diffraction. The bacterial concentrations and pH values of the solution were measured by a spectrophotometer and a pH meter, respectively. The urease secreted by B. licheniformis SRB2 was found to greatly increase the pH values of the liquid medium, which favored the formation of calcium carbonate.As a result, Mg²⁺ and Ca²⁺ ion concentrations decreased greatly due to the biomineralization of calcium carbonate and nesquehonite minerals in the presence of B. licheniformis SRB2 bacterium. There were only few calcium carbonates and no nesquehonite minerals in the control groups. It was also found that the minerals of nesquehonite induced by B. licheniformis SRB2 had a phenomenon of preferred orientation. What was more, even though Mg²⁺ ions inhibited the precipitation of Ca²⁺ ions, but under the action of B. licheniformis SRB2 bacteria, the inhibition effect was significantly declined. The bio-precipitation of calcium carbonate and nesquehonite minerals may represent a new method of pretreatment for the hardness reduction of hard water. The accomplished study is of certain interest for interpretation of the carbonates biomineralization in natural environment, and maybe also has a certain application value in the former processing of hard water

Air pollution knows no boundaries, which means for a city or a region to attain clean air standards, must not only look at the emission sources within its own administrative boundary, but also at sources in the immediate vicinity and those originating from long-range transport. And there is a limit to how much area can be explored to evaluate, govern, and manage as designated airsheds for cities and larger regions. This paper discusses the need from an official airshed framework for India’s air quality management, urban airsheds designated for India’s 131 non-attainment cities under the national clean air programme, and proposes climatically and geographically appropriate regional airsheds to support long-term planning. Between 28 states, eight union territories, 36 meteorological sub-regional divisions, and six regional meteorological departments, establishing the proposed 15 regional airsheds for integrated and collaborative air quality management across India is a unique opportunity.

Abstract: Metal-air batteries provide a most promising battery technology given their outstanding potential energy densities, which are desirable for both stationary and mobile applications in a ‘beyond lithium-ion’ battery market. Silicon- and iron-air batteries underwent less research and development compared to lithium- and zinc-air batteries. Nevertheless, in the recent past, the two also-ran battery systems made considerable progress and attracted rising research interest due to the excellent resource-efficiency of silicon and iron. Silicon and iron are among the top five of the most abundant elements in the earth’s crust, which ensures almost infinite material supply of the anode materials, even for large scale applications. Furthermore, primary silicon-air batteries are set to provide one of the highest energy densities among all batteries, while iron-air batteries are frequently considered as a highly rechargeable system with decent performance characteristics. Considering fundamental aspects for the anode materials, i.e., the metal electrodes, in this review, we will first outline the challenges, which explicitly apply to silicon- and iron-air batteries and prevented them from a broad implementation so far. Afterwards, we provide an extensive literature survey regarding state-of-the-art experimental approaches, which are set to resolve the aforementioned challenges and might enable the introduction of silicon- and iron-air batteries into the battery market in the future.

The choice of dialysate buffer in hemodialysis is crucial, with acetate being widely used despite complications. Citrate has emerged as an alternative due to its favorable effects, yet concerns persist about its impact on calcium and magnesium levels. This study investigates the influence of citrate dialysate (CD) with and without additional magnesium supplementation on CKD-MBD biomarkers and assesses their ability to chelate divalent metals compared to acetate dialysates (AD). A prospective crossover study was conducted in a single center, involving patients on thrice-weekly online hemodiafiltration (HDF). Four dialysates were compared: two acetate-based and two citrate-based. Various biochemical parameters were monitored before and after each dialysis session. Seventy-two HDF sessions were performed in eighteen patients. CD showed stability in iPTH levels and reduced post-dialysis total calcium, with no significant increase in adverse events. Magnesium supplementation with CD prevented hypomagnesemia. However, no significant differences among dialysates were observed in the chelation of other divalent metals. Citrate dialysates, particularly with higher magnesium concentrations, offer promising benefits, including prevention of hypomagnesemia and stabilization of CKD-MBD parameters, suggesting citrate as a viable alternative to acetate. Further studies are warranted to elucidate long-term outcomes and optimize dialysate formulations.

The magnesium ion is an essential cation in the human body and participates in numerous physiological activities. A deficiency in magnesium ions is closely associated with tumor development, and supplementation with magnesium ions has been shown to partially inhibit tumor growth. However, the specific mechanisms by which magnesium ions suppress tumor proliferation remain unclear. Currently, studies have revealed that mitochondria may serve as a crucial intermediate link in the regulation of tumors by magnesium ions. Mitochondria might intervene in the proliferation and invasion of tumor cells by modulating energy metabolism and oxidative stress levels. Therefore, this article provides a comprehensive review of the relationship between magnesium ions and tumors, the mechanisms by which magnesium ions regulate mitochondrial function, and the theoretical basis and prospects of magnesium ion regulation of mitochondrial function for tumor treatment. This review aims to offer insights for clinical tumor treatment strategies involving magnesium ion intervention.

The natural variation in estrogen secretion throughout the female menstrual cycle impacts various organs, including estrogen receptor (ER)-expressed skeletal muscle. Many women commonly experience increased fatigue or reduced energy levels in the days leading up to and during menstruation when blood estrogen levels decline. Yet, it remains unclear whether endogenous 17β-estradiol, a major estrogen component, directly affects energy metabolism in skeletal muscle due to the intricate and fluctuating nature of female hormones. In this study, we employed 3D 31P FID-MRSI to investigate phosphoryl metabolites in the soleus muscle of a cohort of young females (average age: 28 ± 6 years, n = 7) during the early follicular (EF) and peri-ovulation (PO) phases when their blood 17β-estradiol levels differ significantly (EF: 28 ± 18 pg/mL vs. PO: 71 ± 30 pg/mL, p < 0.05), while the levels of other potentially interfering hormones remain relatively invariant. Our findings reveal a reduction in ATP-referenced phosphocreatine (PCr) levels in the EF phase compared to the PO phase for all participants (5.4 ± 4.3%). Furthermore, we observe a linear correlation between muscle PCr levels and blood 17β-estradiol concentrations (r = 0.64, p = 0.014). Conversely, inorganic phosphate Pi and phospholipid metabolite GPC levels remain independent of 17β-estradiol but display a high correlation between EF and PO phases (p = 0.015 for Pi and p = 0.0008 for GPC).The robust association we have identified between ATP-referenced PCr and 17β-estradiol suggests that 17β-estradiol plays a modulatory role in the energy metabolism of skeletal muscle.

: The primary use of the potato is direct consumption. The classification of potatoes into consumption type is made on the basis of consumption evaluation of hydrothermally treated tubers. Nutrient deficiency in the soil, including Mg, contributes to the inhibition of potato growth and development and negatively affects the cooking characteristics of the tubers. Magnesium and biostimulants are responsible for plant nitrogen management. Thus, it is necessary to control the content of harmful nitrates and toxic nitrites in tubers. In potato production, it is also important to maintain appropriate conditions during storage. The purpose of this study was to determine the effect of mineral fertilization with magnesium and a biostimulant preparation during cultivation of edible potato and long-term storage on the traits determining utility-consumption type and the content of harmful nitrogen compounds in tubers. The study was conducted using the early potato variety Satina. In a three-year (2015-2017) three-factor experiment: evaluation date (immediately after harvest and after six months of storage), soil fertilization with mineral magnesium (0, 30, 60, 90 kg MgO ha-1), application of an amino acid biostimulant (0, 1.5, 3.0 l ha-1), five consumption traits of tubers after cooking determining the utility-consumption type of potato were determined. In addition, the consumer safety of the potato was determined based on the nitrate and nitrite content of the tubers. The tendency to overcook tubers significantly depended on all the factors used during potato cultivation. In contrast, the texture and structure of tuber flesh after cooking depended only on mineral fertilization with magnesium. The flesh of the tubers after cooking was most tender (1.0 pt) and firm (1.4 pt) after the application of 60 and 90 kg MgO ha-1, respectively. The moisture level of the flesh after cooking was significantly influenced by the interaction of magnesium fertilization with the biostimulant preparation. The factors of the experiment did not modify the utility-consumption type (B/A), while there was a change in the type in relation to that specified by the grower - general utility (B). The applied cultivation technology and long-term storage did not deteriorate the consumer safety of tubers (&lt;200 mg kg-1) in terms of NO3 (max. 112.1 mg kg-1) and NO2 (max. 1.08 mg kg-1) contents. Organoleptic traits: mealiness, moisture and flesh structure were significantly positively related to nitrate and nitrite content of tubers immediately after harvesting and to nitrite concentration after long-term storage.

Ion beam-assisted deposition (IBAD) has been proposed as a promising texturing technology that uses film epitaxy method to obtain biaxial texture on a non-textured metal or compound substrate. Magnesium oxide (MgO) is the most well explored texturing material. In order to obtain the optimal biaxial texture, the actual thickness of the IBAD-MgO film must be controlled within 12 nm. Due to the bombardment of ion beams, IBAD-MgO has large lattice deformation, poor texture and many defects in the films. In this work, an additional homogeneous epitaxy MgO (epi-MgO) layer has been deposited on the IBAD-MgO layer by electron-beam evaporation. The biaxial texture can be optimized by the deposition of additional epi-MgO layer. The effects of growth temperature, film thickness, deposition rate and oxygen flux on the texture and morphology of the epi-MgO film were systematically studied. After the research of epi-MgO process, the best full width at half maximum (FWHM) values were 2.2 for the out-of-plane texture and 4.8° for the in-plane texture, respectively. Subsequently, the LaMnO3 cap layer and YBa2Cu3O7-x (YBCO) functional layer was deposited on the epi-MgO layer to test the quality of MgO layer. Finally, the critical current density of YBCO films is 6MA/cm2 (77K, 500nm, self-field), indicating that this research provides a high-quality MgO substrate for the YBCO layer.

The development of magnesium calcium phosphate bone cements (MCPCs) have garnered big attention. MCPCs are bioactive and biodegradable and have appropriate mechanical and antimicrobial properties for use in reconstructive surgery. In this study, the cement powders based on a (Ca + Mg)/P = 2 system doped with Zn2+ at 0.5 and 1.0 wt.% were obtained and investigated. After the mixing with a cement liquid, structural and phase composition, morphology, chemical structure, setting time, compressive strength, degradation behavior, solubility, antibacterial activities, and in vitro behaviour of the cement materials were examined. A high compressive strength of 48 ± 5 MPa (mean ± SD) was achieved for the cement made from Zn2+ 1.0-wt.%-substituted powders. The Zn2+ introduction led to antibacterial activity against Staphylococcus aureus and Escherichia coli strains, with an inhibition zone diameter up to 8 mm. Biological assays confirmed that the developed cements are cytocompatible and promising as a potential bone substitute in reconstructive surgery.

Herein, we describe precisely on covalent modification of pure magnesium (Mg) surface and applied to induce in vitro osteogenic differentiation. A new concept, chemical bonding method is proposed for developing stable chemical bonds on Mg surface through serial assembly of bioactive additives including ascorbic acid (AA) and bovine serum albumin (BSA). The coating with such potential materials shows strong integrity to the Mg and could suitable for cell-interface interaction with the host tissue during implantation in bone tissue repair. The physicochemical and electrochemical properties of surface modified Mg assess how these nanoscales layered of biomolecules could demonstrate the significance improvement in chemical stability of coating. The modified Mg-OH-AA-BSA exhibits better anti-corrosion behavior with high corrosion potential (Ecorr ~ ‒ 0.96 V) and low corrosion current density (Icorr ~ 0.2 µA cm-2) as compared to pure Mg (Ecorr ~ ‒1.46 V, Icorr ~ 10.42 µA cm-2). Outer layer of BSA on Mg protects fast degradation rate of Mg which is the consequence of strong chemicals bonds between amine groups on BSA with carboxylic groups on AA. Collectively, the results suggest that surface modified Mg provides strong bio-interface and enhances the proliferation and differentiation of pre-osteoblast (MC3T3-E1) cells through protein-lipid interaction. Owing to this fact, the cost-effective and scalable covalent functionalization of Mg surface inherits biological advantage in orthopedic and dental implants with long term stability.

Magnesium is one of the lightest structural metal used in different industrial sector and many works are present in literature about the study of its reinforcement by fillers addition. Basalt fibres are natural fillers with good mechanical properties, excellent resistance to high temperature and lower cost than carbon fibres. For these aspects, in the last years they are increasingly used in the production of composite materials with polymeric matrices. However, very few information are presents in literature about the use of basalt fibres as reinforcement in metal matrix composite materials. It is well known that the impregnation of fibres reinforcement affects the mechanical behavior of composites materials. The aim of this study is to investigate the impregnation and the behavior of basalt fibres in a magnesium alloy composite material manufactured by a centrifugal casting technique.

To address the question whether there is evidence that drinking water in general or mineral water in particular is effective in preventing diabetes; we performed a literature search of randomized controlled trials (PubMed). The search resulted in very few trials (N = 9) investigating this topic: one trial investigates the effect of increasing water consumption on glycemic control in diabetic patients; two trials investigate the effect of drinking water with a meal in diabetic patients; while six trials compare the effect of mineral rich water with that of low mineralized water on glucose metabolism in healthy subjects. There is evidence that increasing water consumption can improve glucose metabolism and randomized controlled trials with mineral water suggest that waters containing relevant amounts of magnesium can exert an additional effect. The role of bicarbonate; which is present in all the mineral waters used in the trials; will be discussed. Future research needs to investigate the effect of mineral water in prediabetic individuals or individuals with impaired glycemic control.

Background: Bioaerosol can represent a danger to the health. During SARS-CoV-2 pandemic, portable devices were used in different environments and considered a valuable prevention tool. This study has evaluated the effectiveness of the air treatment device “AEROK 1.0” in reducing microbial, particulate and pollen airborne contamination indoors, during normal activity. Methods: In an administrative room, airborne microbial contamination was measured using active (DUOSAS 360 and MD8) and passive sampling; a particle counter was used to evaluate particle concentrations; a Hirst-type pollen trap was used to assess airborne pollen and Alternaria spores. Statistical analysis was performed using SPSS 26.0; p values <0.05 were considered statistically significant. Results: The airborne bacterial contamination assessed by the two different samplers decreased by 55.54% and 69.13%, respectively. The airborne bacterial contamination assessed by passive sampling decreased by 44.16%. For fungi, the reduction was 38.7% by active sampling. Airborne particles (diameters ≥ 1.0, 2.0 μm) and the ratio of indoor/outdoor concentrations of total pollen and Alternaria spp spores significantly decreased. Conclusions: The results highlight the effectiveness of AEROK 1.0 in reducing airborne contamination. The approach carried out represents a contribution to the definition of a standardized model for evaluating the effectiveness of this type of devices.

A review of desiccant dehumidification technologies for improving air-quality has been presented, especially focusing on alternatives for air conditioning systems for minimizing the Sick Building Syndrome. The principles and types of desiccant wheels, as well as the existing selection software for these types of equipment, were reviewed and comparatively evaluated. The study focuses on the Brazilian context, therefore, information about air condition systems and laws of this country were evaluated. Possible applications of desiccant wheels are also analyzed, such as their integration into cooling cycles and the sensible heat wheel. Finally, several commercial desiccant wheel selection software were evaluated, which are useful in many situations. Nevertheless, it was evidenced that the available softwares are not capable of performing an operation analysis for only a specific period. Therefore, it is essential to create computational tools to select desiccant wheels, considering the data from the different Brazilian regions for a year.

Most people living in Europe's cities are still exposed to levels of air pollution deemed harmful by the World Health Organization. In the modern world, air pollution is the foremost concern because of its impact in human health and economy. This strong connection appears gaining a lot of concern, driven by new installed low-cost electrochemical sensors monitoring systems. Highly accuracy, real-time monitoring, daily and yearly statistics, data access from experts or simple users, low-cost equipment and forecasting needs, enforce the market to develop new air quality monitoring systems using advanced technologies and protocols. In this study, a comparison via low-cost electrochemical sensors and of static, fixed site measurement monitoring station, is taking place in Athens, Greece, along with the data quality and Air Quality Index (AQI) including data accuracy and quality of data concerning adverse health effects due to air pollution. The findings presented in this work, relate to different flexible and affordable alternatives adopted during the evaluation and calibration of low-cost gas sensors for the monitoring. The significance of the positive results is particularly useful, especially considering the founding for interference, environmental conditions affections and air quality information including indexes and health recommendations for a specific location.

Mechanical ventilation systems, which are used for breathing support when a person is not able to do it by their own, requires a device for measuring the air flow to the patient in order to monitoring and a assure the magnitude establish by a medical staff. Flow sensors are the conventional devices used for the air flow measuring; however, there were not available in Peru, because of the international demand during COVID-19 pandemic. In this sense, a novel air flow sensor based on orifice plate and an intelligent transducer stage were developed as an integrated design. Advanced methodologies in simulations and experiments using specially designed equipment for this application were carried out. The obtained data was used for a mathematical characterization and dimensions validation of the integrated design. The device was tested in its real working conditions, it was implemented in a breathing circuit connected to a low-cost mechanical ventilation system based on cams. Results indicate that the designed air flow sensor/transducer is a low-cost complete medical device for mechanical ventilators able to provide satisfactorily all the ventilation parameters air flow, pressure and volume over time by measuring the air flow and calculating the others. Furthermore, this device provides directly a filtered equivalent electrical signal for a display or a computer.

Research results of the relationships between air-volume in air-entrained cement paste, mortar and concrete, all designed according to PN-EN 480-1 guidelines are presented in the paper. The cement paste, mortar and concrete, with w/c=0,5 ratio, were prepared using innovative air-entraining cement CEM II/B-V. The air-entraining cement CEM II/B-V was produced using two methods: mixed together with natural or synthetic aerated admixture. The air volume test of the volumetric method was carried out in case of fresh cement paste, mortar and concrete mix. Fresh concretes were evaluated in terms of stability of air entrainment and consistency for 5, 20 and 40 min. The porosity structure parameters, like summarized air-content, specific surface of air voids, air-voids spacing factor and micropores content of hardened concrete, were estimated using computed tomography with a resolution of 2-5 μm. The aim of the research was to determine the dependence between air-content of cement paste, mortar and concrete on the measurement of air-entrainment of cement paste or mortar with the same w/c ratio and type of cement, all designed according to PN-EN 480-1 guidelines. Test results proved that there is a good correlation between the measured air-content of the cement paste, mortar and concrete. Therefore, it is possible to predict the aeration of concrete on the air-entrainment of the mortar.

This study investigates the effects of Zinc (4wt.%) and severe plastic deformation on the mechanical properties of AZ61 magnesium alloy through the stir-casting process. The severe plastic deformation (equal channel angular pressing (ECAP)) has been done followed by T4 heat treatment. The microstructural examinations revealed that the addition of 4wt.%Zn enhances the uniform distribution of β-phase, contributing to a more uniformly corroded surface in corrosive environments. Additionally, dynamic recrystallization (DRX) significantly reduces the grain size of as-cast alloys after undergoing ECAP. The attained mechanical properties demonstrate that after a single ECAP pass, AZ61 + 4wt.%Zn alloy exhibits optimal yield strength (YS), ultimate compression strength (UCS), and hardness. This research highlights the promising potential of AZ61 + 4wt.%Zn alloy for enhanced mechanical and corrosion-resistant properties, offering valuable insights for applications in diverse engineering fields.

Background: The purpuse was to investigate the influence induced by magnesium chloride (MgCl2) and zinc gluconate (ZnG) supplementation on liver and kidney injuries experimentally-induced with acetaminophen (AAPh) and potentiated by ciprofloxacin addition in rats. Material and methods: The experiment was performed on 5 animals groups: group 1 – control, treated for 6 weeks with normal saline, 1mL/kg; group 2 – AAPh, treated for 6 weeks with AAPh, 100 mg/ kg/day; group 3 – AAPh+C, treated AAPh 100 mg/kg/ day for 6 weeks and ciprofloxacin, 50mg /kg/day, only in the last 14 days of the experiment; group 4 – AAPh+C+Mg, with the same treatment as group 3, but, and in the last 14 days, MgCl2 10 mg/ kg/day was added; group 5 – AAPh+C+Zn, with the same treatment as group 3, but, and in the last 14 days, zinc gluconate (ZnG),10 mg/kg/day was added. All administrations were performed by oral gavage. At the end of the experiment, the animals were sacrificed and blood samples were collected for biochemistry examinations. Results: Treatment with AAPh for 6 weeks determined an alteration of the liver function (increases in alanine aminotransferase, aspartate aminotransferase, lactic dehydrogenase and, and gamma-glutamyl transferase) and of renal function (increases in serum urea and creatinine) (P < 0.001 group 2 vs. group 1 for all mentioned parameters). Also, the antioxidant defense capacity was impaired in group 2 vs. group 1 (superoxide dismutase and glutathione peroxidase activity decreased in group 2 vs. group 1, 0.001 < P < 0.01, respectively 0.01 < P < 0.05). The addition of ciprofloxacin, 50 mg/kg/day during the last 14 days resulted in further increases in alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase, urea and creatinine (0.01 < P < 0.05, group 3 vs. group 2). MgCl2 provided a slight protection against liver enzymes increase and a more pronounced protection against the increase in serum urea and creatinine (0.001 < P < 0.01 group 4 vs. group 3). MgCl2 provided a slight protection against the decrease in superoxide dismutase (0.01 < P < 0.05 group 4 vs. group 3), but not against decrease of glutathione peroxidase. The improvement of mentioned parameters could also be seen in case of ZnG, to a higher extent especially in the case of alanine aminotransferase and lactic dehydrogenase (0.01 < P < 0.05 group 5 vs. group 4). Conclusions: This study represents a furthermore proof for beneficial effect of magnesium and zinc salts against toxicity induced by different agents, including antibacterials added to the analgesic and antipyretic acetaminophen; the protection is proven on the liver and kidney’s function; the antioxidant profile improvement has a key role, especially in case of zinc gluconate.

Magnesium alloy stents have been extensively studied in the field of biodegradable metal stents due to their exceptional biocompatibility, biodegradability and excellent biomechanical properties. Nevertheless, the specific in vivo service environment causes magnesium alloy stents to degrade rapidly and fail to provide sufficient support for certain time. This paper presents an overview of the development history and protection strategies for magnesium alloy stents. Alloying, optimizing stent structure and preparing protective coating have improved the corrosion resistance of magnesium alloy stents. Based on the corrosion mechanism of magnesium alloy stents, as well as their deformation during use and environmental characteristics, we present some novel solution strategies aiming at reducing the corrosion rate of magnesium alloys and enhancing the comprehensive performance of magnesium alloy stents. These strategies include adapting protective coatings for the deformation of the stents, preparing rapid endothelialization coatings to enhance the service environment of the stent, and constructing coatings with self-healing functions. It is hoped that this review can help to understand the development of magnesium alloy cardiovascular stents and solve the problems related to magnesium alloy stents in clinical applications at the early implantation stage.

The effects of organic metabolites produced by a sulfate-reducing prokaryote (SRP) in seawater on the anode corrosion process of magnesium alloy were analyzed by open circuit potential, electrochemical impedance spectroscopy, polarization curve, and other electrochemical methods, combined with scanning electron microscopy and X-ray diffraction. It was found that the product film produced by magnesium alloy anode corrosion was not dense, and the surface of the magnesium anode substrate was exposed during the corrosion process. The corrosion of magnesium anode matrix was accelerated by the simulation of different organic metabolites including mannose, glucuronic acid, and glucose. Thus, the synergistic effect of various metabolites produced by SRP in the corrosion process of magnesium alloy may be considered in future studies.

Magnesium and Aluminum alloys continue to be important in the context of modern and lightweight technologies. With the advancement of additive manufacturing (AM), components can be produced directly in a net shape, widen up the usage of magnesium and aluminum alloys as well as holding new ideas for the application of unique physical structures made feasible by 3D printing. Laser-based approach, one of the metal additive manufacturing (AM) methods, enables the formation of arbitrary 3D structures. With promising findings, research in this area is advancing quickly, bringing up a variety of potential applications in both the scientific and industrial sectors. Complex structures can now be manufactured easily utilizing AM technologies to meet the pre-requisite objectives like reduced part numbers, greater functionality, and lightweight, among others. AM has the ability to meet demands by lowering costs and speeding up the manufacturing process. Due to their popularity in numerous high-value applications, aluminum, and magnesium alloys are one of the key material systems being researched in the laser-based additive manufacturing approaches. The review here aims to comprehensively examine the additive manufacturing of magnesium and aluminum alloys, highlighting the influence of the laser-based additive manufacturing approach on the mechanical characteristics, microstructure, and tribological performance of magnesium and aluminum alloys.

Magnesium transporters (MGTs) play a prominent role in the absorption, transport and storage of magnesium in plant cells. In the present study, MGT gene family members were identified and characterized in two species of cucurbitaceae, including C. sativus and C. lanatus. 20, 19, and 20 MGT genes were recognized in C. lanatus, C. sativus, and C. melo, respectively. According to physicochemical properties, the members of each sub-class of MGTs in the species of cucurbitaceae showed the close relationship. Proteins from NIPA were identified as hydrophilic proteins with high stability. Based on phylogenetic analysis, MGT family members were classified into three groups, and NIPAs showed more diversity. Besides, duplication events were not identified between the MGT members in C. lanatus, and C. sativus. According to pocket analysis, residues such as L, V, S, I, and A were frequently observed in the binding sites of MGT proteins in both species. The prediction of post-translation modifications revealed that MSR2 proteins have high phosphorylation potential than other sub-classes in both studied plants. The expression profile of MGTs showed that MGTs are more expressed in root tissues. In addition, MGTs showed differential expression in response to abiotic/biotic stresses as well as hormone application and NIPAs were more induced in response to stimuli in watermelon. The results of this study, as the primary work of MGT gene family, can be used in programs related to cucurbitaceae breeding.

Magnesium and its alloys are not normally used as bio-resorbable temporary implants due to their high and uncontrolled degradation rate in physiological liquid environment. The improvement of corrosion resistance to simulated body fluids (SBF) of a Magnesium alloy (AZ31) coated with poly-β-hydroxybutyrate (PHB) was investigated. Scanning electron microscopy, Fourier transform infrared spectrometer, and contact angle measurements were used to characterize surface morphology, material composition and wettability, respectively. pH modification of the SBF corroding medium, mass of Mg2+ ions released, and weight loss of the samples exposed to the SBF solution, and electrochemical experiment were used to describe the corrosion process and its kinetics. Materials biocompatibility was described by evaluating the effect of corrosion by products collected in the SBF equilibrating solution on hemolysis ratio, cytotoxicity, Nitric Oxide (NO), and total antioxidant capacity (T-AOC). The results showed that the PHB coating can diffusively control the degradation rate of Magnesium alloy improving its biocompatibility: hemolysis rate of materials was lower than 5%, while in vitro Human Umbilical Vein Endothelial Cells（HUVECs) compatibility experiments showed that PHB coated Mg alloy promoted cell proliferation and had no effect on the NO content, the T-AOC was enhanced compared with the normal group and bare AZ31 alloy. PHB coated AZ31 Magnesium alloy extraction fluids have a less toxic behavior due to the lower concentration of corrosion by-products deriving from the diffusion control exerted by the PHB coating films both from metal surface to the solution and vice versa. These findings provide more reference value for the selection of such system as tunable bioresorbable prosthetic materials

The reaction kinetics of burnt lime (CaO) in contact with sea water has been elucidated and compared to its behaviour in fresh water. In the first minutes of contact between burnt lime and water, it "slaked" as CaO reacted with water to yield calcium hydroxide (Ca(OH)2). Subsequently, calcium hydroxide reacted with magnesium, sulphate and carbonate from the sea water to yield magnesium hydroxide (Mg(OH)2), calcium sulphate dihydrate (gypsum, CaSO4·2H2O) and calcium carbonate (CaCO3), respectively. In a closed system of 1% CaO in natural sea water (where the supply of sulphate, magnesium and carbonate is limited), more than 90% reacted within the first 5 hours. It is foreseen that in an open system, like a marine fjord, it will react even faster. The pH 8 of sea water close to the CaO particle surface will immediately increase to a theoretical value of about 12.5 but will, in an open system with large excess of sea water, rapidly fall back to pH 10.5 being equilibrium pH of magnesium hydroxide. This is further reduced to < 9 due to the common ion effect of dissolved magnesium in sea water and then be diluted to the sea water background pH, about 8. Field test dosing CaO particles to sea water showed that the pH of water between the particles stayed around 8.

The anodic polarization response of magnesium alloy AZ31 was characterized during exposure to aerated 0.1M NaCl solutions with millimolar additions of NaVO₃, Na₃PO₄, Na₂HPO₄, NaF and various pairings to assess their ability to inhibit corrosion kinetics and retard localized corrosion. Each of the candidate inhibitors reduced the corrosion rate of the alloy to some degree. A Na₃PO₄ - NaVO₃ pair produced a powerful inhibiting response decreasing the corrosion rate to about 10^-7 A/cm², which was two orders of magnitude lower than the uninhibited control case. A Bliss Independence assessment indicated that this inhibitor pair acted synergistically. A Na₂HPO₄ - NaVO₃ pair reduced the corrosion rate to 10^-6 A/cm² but was not assessed to be acting synergistically. The NaVO₃ - NaF pair did not reduce the corrosion rate significantly compared to the control case and was an antagonistic pairing. SEM imaging showed film formation due to exposure, which appears to be the origins of the observed inhibition. The resistance to localized corrosion was assessed as the difference in the breakdown potential and the corrosion potential with larger values indicating a lower probability of localized corrosion during free corrosion exposures. Effects of the inhibitors on this characteristic were mixed, but each of the inhibitor pairs yielded potential differences in excess of 100mV. A conceptual conversion coating process based on a mixture of vanadate and phosphate compounds were demonstrated. A fluoride-bearing formulation produced coatings whose total impedance was increased by a factor or 2 compared to an uncoated control. A fluoride-free formulation produced coatings whose corrosion resistance was increased by more than a factor of 3.

Magnesium (Mg)-based biomaterials are promising candidates for bone and tissue regeneration. Alloying and surface modifications provide effective strategies for optimizing and tailoring their degradation kinetics. Nethertheless, biocompatibility analyses of Mg-based materials are challenging due to its special degradation mechanism with continous hydrogen release. In this context, the hydrogen release and the related (micro-) milieu conditions pretend to strictly follow in vitro standards based on ISO 10993-5/-12. Thus, special adaptions for the testing of Mg materials are necessary, which have been described in a previous study from our group. Based on these adaptions, further developments of a test procedure allowing rapid and effective in vitro cytocompatibility analyses of Mg-based materials based on ISO 10993-5/-12 are necessary. The following study introduces a new two-step test scheme for rapid and effective testing of Mg. Specimens with different surface characteristcis were produced by means of plasma electrolytic oxidation (PEO) using silicate-based and phosphate-based electrolytes. The test samples were evaluated for corrosion behavior, cytocompatibility and their mechanical and ostogenic properties. Thereby, two PEO ceramics could be identified for further in vivo evaluations.

Air pollution, particularly fine particulate matter (PM2.5), poses a significant threat to public health, especially in rapidly urbanizing areas like Lagos State. Despite the severity of the issue, there is a lack of comprehensive data on PM2.5 levels and the Air Quality Index (AQI) in Lagos. This study leverages data from AirQo, an innovative air quality monitoring network using low-cost sensors, to provide a detailed assessment of PM2.5 concentrations and AQI across eight locations in Lagos State, Nigeria. This approach offers real-time, continuous monitoring, filling a critical data gap in the region's air quality management efforts. This study uses AirQo data to assess the concentration levels and spatial distribution of PM2.5 and AQI across the selected eight locations. Data on PM2.5 concentrations were obtained from AirQo sensors deployed across the eight strategic locations in Lagos. The spatial distribution of PM2.5 levels and AQI were analyzed, and the results were compared with national and international air quality standards. The findings revealed that PM2.5 levels (minimum – 6.28 µg/m3 (Ikeja) and maximum - 204.68 µg/m3 (Banana Island) in many areas of Lagos exceed annual WHO and national air quality guidelines, indicating significant health risks. The spatial analysis identified pollution hotspots, particularly in densely populated and industrial regions. The data suggested vehicular emissions and industrial activities as major contributors to high PM2.5 levels. This study underscores the severe air quality issues in Lagos State, emphasizing the need for immediate and targeted interventions to mitigate PM2.5 pollution. The use of AirQo sensors proved effective in providing accurate and timely data for air quality assessment. It is recommended that Lagos State implements stricter emission controls, promotes cleaner technologies, and enhances public transportation systems to reduce traffic-related pollution. Additionally, expanding the air quality monitoring network and incorporating more environmental data will provide a more comprehensive understanding of air pollution impacts, thereby facilitating better policy and public health decisions.

Air traffic congestion is caused by the unbalance between increasing traffic demand and saturating capacity. Flight delay not only causes huge economical lost, but also has very negative environmental impact in the whole air transportation system. In order to identify the impact of extended TMA on airport capacity, an airspace capacity assessment method based on augmented cell transmission model was proposed. Firstly, the airspace structure was modeled with points, segments, layers, and cells. Secondly, mixed integer linear programming model was built up with maximum throughput or capacity as the objective function. Finally, genetic algorithm was used to find the optimal result, and the results were validated by comparing with the fast-time simulation results generated by total airspace and airport modeler (TAAM) software. It is found that the proposed method could achieve a relatively accurate result in a much affordable and fast way. The numerical results could be very helpful for air traffic controllers to analyze the dynamic traffic flow entering and exiting TMA, so as to make decisions via reasonable analysis and do planning in advance by referring to the airport capacity.

The coronavirus disease (COVID-19) pandemic caused by spreading rapidly a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has imposed a unique situation for the humanity. Sao Paulo has reported 124,105 confirmed cases of COVID-19 and 5,623 deaths up to June 14th, being considered the epicenter of the pandemic in Brazil and in South America. Due to the measures for social distancing, there was a drop in the air pollution concentration in Sao Paulo. Starting on March 16th, 2020, we broke 90 days of social distancing into 13 weeks and compared to an equivalent period in 2019. We investigated the air quality improvement during the quarantine period and compared the associated avoided deaths to COVID-19 burden deaths. Nitrogen dioxide (NO₂) was the best indicator of air quality in the analyzed weeks, since its reduction reached 58 %. Our study showed that the 5,623 deaths occurred during the analyzed weeks of quarantine represents an economic health loss of US$ 10.5 billion. In opposite, we observed a significant air quality improvement due to pollutants concentrations’ reductions during the analyzed weeks. Considering PM₁₀, PM_2.5 and NO₂, the decrease of concentration levels respectively avoided 78, 337 and 387 premature deaths and prevented up to US$ 1.5 billion on health costs. These results highlight the importance of continuing to enforce existing air pollution regulations and measures to protect human health both during and after COVID-19 pandemic.

The last decade has seen a significant growth in low-cost air quality monitoring systems (LCAQMS) adoption, mostly driven by the spatial density limitations of traditional regulatory grade networks which restrict their effectiveness in several settings. The EU's regulatory framework advise for deploying one air quality monitoring unit per roughly 170,000 people or 15 square kilometers which is insufficient for capturing high spatio-temporal variance in complex urban scenarios. Often these settings are characterized by distributed emissions in small roads subjected to intense cars traffic, house heating driven emissions and frequently subjected to canyon effects. The Air Heritage project in Portici, funded by the EU's Urban Innovative Actions (UIA) program, addressed these challenges by integrating low-cost sensors with traditional monitoring systems and engaging the community in pervasive measurement strategies. The project highlights the importance of individualized sensor calibration and frequent recalibrations to maintain accuracy. It also showcases the benefits of citizen science approaches, IoT infrastructures, AI components, and geostatistical sensor fusion algorithms for mobile and opportunistic air quality measurements. This paper reports on the lessons learned and experiences from the Air Heritage project, aiming to guide future implementations in similar contexts. By sharing these insights along with the gathered datalake, we aim to inform stakeholders, including researchers, public authorities, and citizens, about effective strategies for deploying and utilizing LCAQMS to enhance air quality monitoring and public awareness.

Point defects induced by doping rare earth elements RE (Nd, Er) into the magnesium oxide host were investigated by classical atomistic simulations utilising the General Utility Lattice Program (GULP). Formation and association energies were calculated for the potential defect structures. Both isolated defects and defect complexes were considered. The most energetically favourable structures of defect complexes were found for rare earth doped and Li co-doped systems. The correlation between the association energy and the structure of the defect complex was investigated. The influences of Li were revealed with respect to energy and structure. The simulation results contribute to the understanding of the point defects of doped MgO and how Li influences the doping of rare earth elements in the MgO host.

This study investigates how root environment acidification impacts tea seedlings and the role of magnesium (Mg) in mitigating these effects. We examine varying pH and Mg levels' influence on tea seedlings' resistance to abiotic stress, focusing on antioxidant capacity and nutritional content. In a hydroponic experiment, we varied root pH (3.5, 5.0, 6.5) and Mg concentrations (0.01, 0.4, 0.8 mM), assessing parameters like antioxidant capacity, peroxidative damage, and nutritional content at 1, 7, 15, and 30 days post-treatment. Root environment acidification and Mg deficiency worsened peroxidative damage in tea plant leaves and roots. Increased Mg supplementation enhanced antioxidant enzyme activity, reducing malondialdehyde and mitigating oxidative damage from root environment acid stress. Under acid stress, 0.8 mM Mg significantly increased tea leaf polyphenols, amino acids, and water-soluble extracts. Mg notably boosted chlorophyll content, surpassing lower Mg levels at pH 5. Additionally, Mg reversed root vitality inhibition induced by acid stress, leading to increased nitrogen, potassium, and Mg concentrations in leaves, promoting balanced nutrient absorption. Mg supplementation is crucial for enhancing tea plant antioxidant capacity, alleviating growth inhibition from root environment acid stress, and improving chlorophyll content and root vitality, highlighting Mg's significance in tea cultivation and broader agricultural practices.

Magnesium, as one of the most abundant cation in the human body, plays an important role in both physiological and pathological processes. In this study, it was shown that a promising biomedical material Mg-substituted hydroxyapatite (Mg-HA) can be synthesized via fast mechanochemical method. For this method, the nature of magnesium-contained carriers was shown to be important. When using magnesium oxide as a source of magnesium, the partial insertion of magnesium cations into the apatite structure occurs. In contrast, when magnesium hydroxide or monomagnesium phosphate is used, a single-phase Mg-HA is formed. Both experimental and theoretical investigations showed that an increase in the Mg content leads to a decrease in the lattice parameters and unit cell volume of Mg-HA. Density functional theory calculations showed the high sensitivity of the lattice parameters towards the crystallographic position of the calcium site substituted by magnesium. It was shown experimentally that insertion of magnesium cations decreases the thermal stability of the hydroxyapatite. The thermal decomposition of Mg-HA leads to the formation of a mixture of stoichiometric HA, magnesium oxide and Mg-substituted tricalcium phosphate phases.

Structural evolution, mechanical and tribological properties of Al-Mg alloy admixed with 5, 10 and 15 vol.% of iron powder using multi-pass friction stir processing (FSP) have been studied. Homogeneous distribution of intermetallic compound (IMC) particles were achieved after 4 FSP passes what resulted in increasing the stir zone hardness and ultimate tensile stress with simultaneous loss in the ductility. The reinforcement of the aluminum alloy matrix with IMCs allowed reducing wear at the same magnitude of friction. Subsurface composite tribological layer was formed on the FSPed samples as a result of rubbing against a steel counterbody.

A wide variety of substances have been used to anaesthetise invertebrates, but many are not anaesthetics and merely incapacitate animals, rather than preventing pain. Much is now known about the mode of action of modern clinical and veterinary anaesthetics because of their use on human beings and other vertebrates. In essence, the role of an ideal general anaesthetic is to act as a muscle relaxant, an analgesic, an anaesthetic and an amnesic. To achieve all these properties with a single substance is difficult and various adjuvants usually need to be administered, resulting in a cocktail of drugs. In a clinical setting, the vast majority of patients are unaware of surgery being carried out and have no memory of it, so they can claim to have felt no pain, but this is much more difficult to demonstrate in invertebrates. Here we show that 1% MgCl2, a muscle relaxant, is a useful adjuvant for the clinical anaesthetic isoflurane on Octopus vulgaris when applied for 10 minutes before the clinical anaesthetic. After this, full anaesthesia can be achieved in 5 minutes using only 1% isoflurane and from which full recovery takes place rapidly in about 10 to 15 minutes. This reduces stress on the animal and minimises the quantity of anaesthetic used.

Rare earth rich magnesium alloys are used in aerospace and automotive fields because of their high specific strength and good castability. However, due to their low corrosion resistance, protective surface treatments, such as conversion coating or electroless plating are necessary, when they have to be used in humid or corrosive environments. The present study was aimed to evaluate the effect of Plasma Electrolytic Oxidation (PEO) and different surface roughness (Ra≈0.8 μm and Ra≈0.3 μm) on the rotating bending fatigue of an innovative Mg alloy, with a high content of Nd (up to 3.1 wt%) and Gd (up to 1.7 wt %). Fatigue tests revealed a 15% decrease in the fatigue strength of the PEO treated alloy (fatigue strength = 88 MPa) with respect to the bare alloy (fatigue strength = 103 MPa). The reduction of fatigue strength was mainly due to the residual tensile stresses induced by the PEO treatment. The effect of surface roughness on the bare alloy was, instead, negligible. The mechanisms of crack initiation were similar in the untreated and PEO treated alloy, with crack nucleation sites located in correspondence of large facets of the cleavage planes.

Environment pollution is the major problem for all the sectors. In environment pollution there are different types of pollution is included such as air pollution, water pollution, soil pollution etc. In these types of pollution most of it is air pollution. There are many reasons for pollution of air. Human advance in science but one of the major draw backs of science is the pollution of air rapidly. Air pollution is injurious to health. Every year a large number of people died for the effects of air pollution. It can be improved in many ways among these ways technology upgradation plays a major role here. There are various method that prevent air pollution. Many researchers tried and is trying to prevent the air pollution in many ways. In this review paper I summarise the existing research on different ways for preventing air pollution in addition I will discuss the gaps and future aspect on this topic.

Purpose: This study aimed to focus on the design and development of low-cost DIY air purifiers, using a ventilating fan, air pump, water pump, and an ultrasonic generator, with regard to filtration efficacy and also cost-effectiveness that can be used during the COVID-19 pandemic and haze pollution. Methods: Six types of household air purifiers, incorporating a HEPA filter, a HEPA filter & electrostatic fiber, an air pump, an air pump & ultrasonic wave, a water pump, and a water pump & ultrasonic wave, were fabricated. The amount of particulate matter (PM) and CO₂ levels were recorded at 0, 10, 20, 30, and 60 min, then, repeated 3 times. After 10 min of the 3^rd experiment of each study, the last measurement of air pollution would be recorded. Results: At 60 min, the HEPA filter & electrostatic fiber showed the best performance regarding reduction of PM and CO₂ levels. The highest PM reduction rate had occurred at 30 min using an air pump procedure (99.330 to 100%). The CO₂ levels of all experiments had fluctuated at different times. After 10 min of a closed machine, HEPA filter & electrostatic fiber revealed the highest rate of PM elevation, while PM levels of all water-based purifier systems were decreased. A water pump and air pump were the cheapest air cleaners, when taking into account maintenance expenses and electricity charges. Conclusion: An air pump is the optimum method for reducing particulate matter at minimum cost but without the benefit of reduced humidity, while the HEPA filter & electrostatic fiber is the best system to decrease PM levels, but this requires an enclosed structure at the inlet to prevent dust coming back into the room. As filtration efficiency is increased by the use of filters & electrostatic fiber mechanisms, the more expensive the system becomes.

The rural communities are affected by gaseous emissions from intensive livestock production. Practical mitigation technologies are needed to minimize emissions from stored manure and improve air quality inside barns. In our previous research, the one-time surficial application of biochar to swine manure significantly reduced emissions of NH3 and phenol. We observed that the mitigation effect decreased with time during the 30-day trials. In this research, we hypothe-sized that bi-weekly reapplication of biochar could improve the mitigation effect on a wider range of odorous compounds using larger scale and longer trials. The objective was to evaluate the effectiveness of biochar dose and reapplication on mitigation of targeted gases (NH3, odor-ous VOCs, odor, GHGs) from stored swine manure on a pilot-scale setup over 8-weeks. The bi-weekly reapplication of the lower biochar dose (2 kg/m2) showed much higher significant percent reductions of emissions for NH3 (33% without & 53% with reapplication) and skatole (42% without & 80% with reapplication), respectively. In addition, the reapplication resulted in the emergence of statistical significance to the mitigation effect for all other targeted VOCs. Spe-cifically, for indole, the % reduction improved from 38% (p=0.47, without reapplication) to 78% (p=0.018, with reapplication). For phenol, the % reduction improved from 28% (p=0.71, without reapplication) to 89% (p=0.005, with reapplication). For p-cresol, the % reduction improved from 31% (p=0.86, without reapplication) to 74% (p=0.028, with reapplication). For 4-ethyl phenol, the percent emissions reduction improved from 66% (p=0.44, without reapplication) to 87% (p=0.007, with reapplication). The one-time 2 kg/m2 and 4 kg/m2 treatments showed similar effectiveness in mitigating all targeted gases, and no statistical difference was found between the dosages. The one-time treatments showed significant % reductions of 33% & 42% and 25% & 48% for NH3 and skatole, respectively. The practical significance is that the higher (one-time) biochar dose may not necessarily result in improved performance over the 8-week manure storage, but the bi-weekly reapplication showed significant improvement in mitigating NH3 and odorous VOCs. The lower dosages and the frequency of reapplication on the larger-scale should be explored to optimize biochar treatment and bring it closer to on-farm trials.

The physical environment plays an important role in the transmission of respiratory infections like Covid-19. To find relevant articles on environmental factors influencing respiratory infection outbreaks, we searched Pub med Central on the following topics: 1. Environmental pollution causing coronavirus fatality- 73 results, relevant 1 article, 2. Environmental factors affecting Covid-19, 149 results from which there were 6 relevant articles, 3. Impact of air pollution on Covid-19 fatality, 10 results, relevant 3 articles, 4. Environmental factors affecting respiratory viruses- 10646 results were obtained, 2 relevant articles. We searched Google scholar on environmental factors affecting Covid-19 transmission and found 7 relevant papers. We excluded the duplicates in each of the key words search. Date of search was on 20^th April 2020. All articles included in results were scrutinized and relevance of articles was based on their content that discussed meteorological and physical environment factors in the spread and severity of Covid-19. We have discussed factors like air pollution, smoking, air temperature, humidity and air velocity as contributing factors. If meteorological factors are conducive to spread in a particular area, we need protective measures way before a respiratory infection outbreak occurs. Covid-19 is a lesson learnt the hard way, and we must enable people to practice hygienic practices with limited resources but high level of protection that it provides. Air pollution control can prevent priming of respiratory system which shall further protect from pulmonary infections.

Shenzhen is China’s top ten clean air city and the cleanest air megacity. Even so, epidemiologic studies have shown ambient air pollution had significant adverse impacts on human health in this less polluted city. In this study, the concentrations of six criteria air pollutants (PM2.5, PM10, O3, NO2, SO2, and CO) from 2014 to 2017 were analyzed and compared to thresholds of both national and international air quality standards. The results showed concentrations of all air pollutants were below target values of current national air quality standard, but levels of particulate matter (PM) and O3 were still much higher than the recommended levels by the World Health Organization. Within national air quality standards, the number of over-limit days was rare with few variations between highly polluted and low pollution areas. The air quality improvement was slowing down recently. Our results suggest annual and daily thresholds for PM are too loose for air quality improvement in Shenzhen. Hence, we call for evaluation and establishment of tougher air quality standard.

Abstract: This article explores the intricate relationship between environmental degradation, specifically air pollution, and economic growth in the Sultanate of Oman spanning the period from 1990 to 2022. We employ cointegration and vector error correction models to uncover both short- and long-term dynamics in the association between air pollution and economic growth. Fur-thermore, Granger causality analysis is utilized to investigate the causal links between these crucial variables. This data encompasses factors related to environmental quality and various control variables. The empirical results unveil a sustained long-term cointegration connection between the variables. Additionally, our findings highlight a statistically significant positive impact of economic growth and energy consumption on CO2 emissions. Furthermore, the short-term analysis reveals an annual adjustment of approximately 14.1% in N2O emissions dis-equilibrium. The Granger causality study indicates unidirectional causal relationships involving N2O emissions, economic growth, and CO2 emissions. The implications of these findings for Oman's policy landscape are substantial. To effectively reduce greenhouse gas emissions, it is imperative for Oman to establish robust climate change policies. Additionally, the government can play a pivotal role in encouraging and endorsing the use of renewable energy sources, such as green hydrogen, as a promising alternative to traditional oil and gas resources.

As the haze engulfed the Delhi NCR after Diwali there is a panic in public about its causes and consequences. Here are some facts and figures to know the truth behind the scene. Temperature fell down from 24’C on October 31 to 21’C on November 2 as recorded at UPPCB station at sector-125, Noida which is adjacent to Delhi a very strategic location and can be considered as reference point for Delhi-NCR. The details of the study conducted is given below.

This publication aims to disseminate a step-by-step process that walks through the conceptualization and building of a low-cost (~ $150 monitoring device for airborne fine particulate matter (PM2.5), based on miniaturized sensors and components. Details on the implementation of the hardware and software are provided which facilitate the data acquisition, capture and analysis. The central components and their setup discussed in what follows include: the sensor device (called “P.ALP” – Ph.D. Air quality Low-cost Project), Arduino IDE (Integrated Development Environment) and R code (open-access software). A monitoring device for PM2.5, using low-cost sensors and technologies was successfully conceptualized, designed, and implemented. The P.ALP monitoring system was designed and developed to be a basic device, which can be further customized and implemented using the wide range of low-cost sensors available on the market.

Elevated indoor CO2 levels might have adverse effects on human health. However, the introduction of outdoor air to lower indoor CO2 concentrations results in significant HVAC energy consumption. Aligning with office hours and the natural light cycle, the utilization of photosynthesis in living walls offers an energy-efficient and sustainable solution for the mitigation of high CO2 levels in office spaces. This study experimentally investigates the impacts of the carbon fixation pathways, light intensity, and substrate moisture content on the CO2 removal rate of living walls at the room scale. Furthermore, the fresh air energy-saving effects of living walls under different scenarios are accurately simulated in EnergyPlus. The results demonstrate that choosing C3 plants over CAM plants in living walls yields higher CO2 removal efficiency. In a 30-m2 office room accommodating 2-3 occupants, living walls can reduce the demand for fresh air by 12.3%-27.8% and decrease fresh air energy consumption by 11.2%-28.2%. The city with the highest energy savings has energy savings that are 4.5 times greater than those of the city with the lowest energy savings. The findings of this research promote the application and development of living walls, thus providing a viable solution for improving indoor air quality.

This case study investigates the effects of ventilation intervention on measured and perceived indoor air quality (IAQ) in a repaired school where occupants reported IAQ problems. Occupants´ symptoms were suspected to be related to the impurities leaked indoors through the building envelope. The study’s aim was to determine whether a positive pressure of 5-7 Pa prevents the infiltration of harmful chemical and microbiological agents from structures, thus decreasing symptoms and discomfort. Ventilation intervention was conducted in a building section comprising 12 classrooms and was completed with IAQ measurements and occupants´ questionnaires. After intervention, the concentration of total volatile organic compounds (TVOC) and fine particulate matter (PM_2.5) decreased, and occupants´ negative perceptions became more moderate compared to those for other parts of the building. The indoor mycobiota differed in species composition from the outdoor mycobiota, and changed remarkably with the intervention, indicating that some species may have emanated from an indoor source before the intervention.

Marine cold air outbreaks (MCAOs) are large-scale events in which cold air masses are advected over open ocean. It is well-known that these events are linked to the formation of polar lows and other mesoscale phenomena associated with high wind speeds, and that they therefore in some cases represent a hazard to maritime activities. However, it is still unknown whether MCAOs are generally conducive to higher wind speeds than normal. Here this is investigated by comparing ocean near-surface wind speeds during MCAOs in atmospheric reanalysis products with different horizontal grid spacings, along with two case studies using a convection-permitting numerical weather prediction model. The study regions are the Labrador Sea and the Greenland–Iceland–Norwegian (GIN) Seas, where MCAOs have been shown to be important for air–sea interaction and deep water formation. One of the main findings is that wind speeds during the strongest MCAO events are higher than normal and higher than wind speeds during less severe events. Limited evidence from the case studies suggests that reanalyses with grid spacings of more than 50 km underestimate winds driven by the large ocean–atmosphere energy fluxes during MCAOs. The peak times of MCAO usually occur when baroclinic waves pass over the regions. Therefore, the strong wind episodes during MCAOs generally last for just a few days. However, MCAOs can persist for 50 days or more.

The term Air Quality (AQ) pertains to the standard of air, which has a direct impact on the health and well-being of individuals. It is crucial to maintain high Air Quality (AQ), for better health and productivity. Though most of people spend more time indoors nowadays, it is not to be overlooked that the pollutant concentration in indoor air is directly linked to the outdoor air quality. Due to the changes in occupancy patterns, outdated maintenance of ventilation systems, and structural flaws in buildings, the indoor air is significantly polluted; pollutants emitted outdoors enter indoor air through open windows, ventilation systems and infiltration. In this paper, we have proposed a new technique, DTMCPM (discrete-time Markov chain (DTMC) model for the analysis and forecasting of AQ, using the power method). Specialized sensors and equipment to measure different pollutants, such as particulate matter, ozone, nitrogen dioxide, sulfur dioxide, benzene and toluene, are used to collect data by the Institute of Pakistan Air Quality Monitor in various cities; the data is converted to US EPA standard for all pollutant species. This data is used to calculate the transition matrix, steady-state values and mean return rate for the analysis of IAQ. The calculated and actual return rates have been compared and the proposed model is found to have a low average prediction error of 2.356%.

Magnesium-silver alloys are of high interest for the use as temporary bone implants due to their antibacterial properties in addition to biocompatibility and biodegradability. Thin wires in particular can be used for scaffolding, but the determination of their degradation rate and homogeneity using traditional methods is difficult. Therefore, we have employed 3D imaging using X-ray near-field holotomography with sub-micrometer resolution to study the degradation of thin (250 μm diameter) Mg-2Ag and Mg-6Ag wires. The wires were studied in two states, recrystallized and solution annealed to assess the influence of Ag content and precipitates on the degradation. Imaging was employed after degradation in Dulbecco’s modified Eagle’s medium and 10% fetal bovine serum after 1 to 7 days. At 3 days of immersion the degradation rates of both alloys in both states were similar, but at 7 days higher silver content and solution annealing lead to decreased degradation rates. The opposite was observed for the pitting factor. Overall, the standard deviation of the determined parameters was high, owing to the relatively small field of view during imaging and high degradation inhomogeneity of the samples. Nevertheless, Mg-6Ag in the solution annealed state emerges as a potential material for thin wire manufacturing for implants.

Aquatic animals have unique physiological mechanisms to absorb and retain minerals from their diets and water. Research and development in the area of mineral nutrition of farmed fish and crustaceans have been relatively slow and major gaps exist in the knowledge of trace element requirements, physiological functions and bioavailability from feed ingredients. Quantitative dietary requirements have been reported for three macroelements (calcium, phosphorus and magnesium) and six trace minerals (zinc, iron, copper, manganese, iodine and selenium) for selected fish species. Mineral deficiency signs in fish include reduced bone mineralization, anorexia, lens cataracts (zinc), skeletal deformities (phosphorus, magnesium, zinc), fin erosion (copper, zinc), nephrocalcinosis (magnesium deficiency, selenium toxicity), thyroid hyperplasia (iodine), muscular dystrophy (selenium) and hypochromic microcytic anaemia (iron). An excessive intake of minerals from either diet or gill uptake causes toxicity and therefore a fine balance between mineral deficiency and toxicity is vital for aquatic organisms to maintain their homeostasis either through increased absorption or excretion. Release of minerals from uneaten or undigested feed and from urinary excretion can cause eutrophication of natural waters, which requires additional consideration in feed formulation. The current knowledge in mineral nutrition of fish is briefly reviewed.

Although fragility fractures, osteoporosis, sarcopenia and frailty are becoming more prevalent in our aging society the treatment options are limited and preventative strategies are needed. Despite magnesium being integral bone and muscle physiology the relationship between dietary magnesium and skeletal muscle and bone health has not been investigated concurrently before. We analysed cross-sectional associations between dietary magnesium and skeletal muscle mass (as fat free mass – FFM), grip strength and bone density (BMD) in 156,575 men and women aged 39-72 years from the UK Biobank cohort. FFM was measured with bioelectrical impedance and expressed as the percentage of body weight (FFM%) or divided by body mass index (FFM_BMI). Adjusted mean grip strength, FFM%, FFM_BMI, and BMD were calculated according quintiles of dietary magnesium, correcting for covariates. Significant inter-quintile differences across intakes of magnesium existed in men and women respectively of 1.1% and 2.4% for grip strength, 3.0% and 3.6% for FFM%, 5.1% and 5.5% for FFM_BMI, and 2.9% and 0.9% for BMD. These associations are as great or greater than annual measured losses of these musculoskeletal outcomes indicating potential clinical significance. Our study suggests that dietary magnesium may play a role in musculoskeletal health and have relevance for population prevention strategies for sarcopenia, osteoporosis and fractures.

Semi-solid feedstock of AZ80 magnesium alloy modified by minor rare-earth Y element (0, 0.2, 0.4, 0.8 wt.%) were fabricated by strain induces melting activated (SIMA) in the form of extrusion and partial remelting. The effect of Y addition on the microstructure evolution of extruded and isothermal treated alloy was observed by optical microscope (OM), scanning electron microscope (SEM), X-ray diffraction (XRD) and quantitative analysis. The results show that the Y addition can refine the microstructure and make the β-Mg17Al12 phases agglomerating. During the subsequent isothermal treatment at 570℃, the average solid grain size, shape factor and liquid fractions increased with prolonged soaking time. Smaller spheroidal solid grains and the larger shape factor were obtained due to Y addition. The coalescence and Ostwald ripening of solid grains operated the coarsening process simultaneously. The coarsening rate constants of AZ80M1 (0.2 wt.% Y addition) of 164.22 μm3s-1 was approximately four times less than the un-modified AZ80 alloy of 689.44 μm3s-1. In contrast, the desirable semi-solid structure featured by fine, well globular solid grains and appropriate liquid fractions and shape factor was achieved in AZ80M1 alloy treated at 570℃ for 20-30 min.

The air attenuation of pure tones as a function of temperature and humidity is well known and described in ISO and ANSI standards. However, room acoustic measurements are performed in octave bands, which is the reason for a complicated, nonlinear behavior of the air attenuation. It is known that room acoustic measurement results depend on air temperature and humidity, and these atmospheric data should always be reported in connection with room acoustic measurements. A calculation model for the air attenuation can make it possible to normalize the room acoustic results. For accurate results it is possible to apply a summation method on each time sample in the impulse response. An approximation to the air attenuation at and above 1 kHz is possible by linearization using the pure-tone attenuation of two different frequencies, one frequency valid for the early part of the impulse response, and another frequency valid for the later part of the impulse response. The purpose of the suggested methods is to make it possible to normalize room acoustic measurements to a standard atmosphere.

This study investigates the characteristics of formaldehyde (HCHO) concentration and its reduction in newly constructed apartment buildings in Dubai. It addresses the significant health risks of high HCHO levels due to poor ventilation and extensive use of VOC-emitting materials. The research explores the effectiveness of various mitigation strategies, including air purifiers, photocatalyst applications, and window ventilation, in the living room, master bedroom (MBR), Room 1, and Room 2. HCHO concentrations were measured under different conditions: sealed windows, operation of an air purifier with a VOCs filter, and the application of a photocatalyst. The study followed a quantitative approach, recording real-time HCHO levels over 24 hours. Results indicated that sealing windows led to HCHO concentrations surpassing the domestic standard of 0.1 ppm, with the MBR recording the highest concentration at 0.73 ppm. The air purifier showed minimal impact within the first 8 hours but achieved an 18% reduction after 24 hours of operation. Applying a photocatalyst to room surfaces resulted in a 50% reduction in HCHO levels. Ventilation through window openings significantly improved air exchange rates, with the air exchange per hour (ACH) increasing proportionally with window opening size. Smaller rooms with larger window-to-volume ratios, such as Room 1 and Room 2, maintained HCHO concentrations below the WHO standard of 0.1 ppm with partial window openings. The study concludes that window ventilation is the most effective strategy for reducing HCHO concentrations, highlighting the importance of integrating comprehensive ventilation designs in modern residential buildings to ensure healthier indoor environments in Dubai.

CAMx-LPiG (Comprehensive Air Quality Model with Extensions – Linear Plume in Grid) is an online hybrid model, based on the Chemistry and Transport Model (CTM) CAMx, that includes a sub-grid scale module to simulate the dispersion of linear road traffic emissions, called LPiG. LPiG is a plume in grid module specifically developed by extending the capabilities of the Lagrangian puff sub-grid model available in CAMx. The online integration of the local scale model within the Eulerian CTM allows for a multiscale simulation of air quality from the regional scale to the urban scale, preserving a coherent description of the chemical state of the atmosphere at all spatial scales and avoiding any double counting of the emissions simulated by the sub-grid module. In this work the model is presented and evaluated against measured NO2 concentrations for the city of Milan for the month of January 2017. The model is able to introduce road traffic induced gradient in NO2 concentration at sub-grid resolution. Moreover, CAMx-LPiG is shown to reduce the bias compared to CAMx stand-alone simulations.

Air corridors are an integral part of the advanced air mobility infrastructure. They are the virtual highways in the sky for transportation of people and cargo in the controlled airspace at an altitude of around 1000 ft. to 2000 ft. above the ground level. This paper presents fundamental insights into the design of air corridors with high operational efficiency as well as zero collisions. It begins with the definitions of air cube, skylane or track, intersection, vertiport, gate, and air corridor. Then, a multi-layered air corridor model is proposed. Traffic at intersections is analyzed in detail with examples of vehicles turning in different directions. The concept of capacity of an air corridor is introduced along with the nature of distribution of locations of vehicles in the air corridor and collision probability inside the corridor are discussed. Finally, the results of simulations of traffic flows are presented.

Air pollution is responsible for any adverse effects on human beings. Thermal discomfort, on the other hand, is able to overload the human body and eventually provoke health implications due to the heat imbalance. Methods: The aim of the present work is to study the behavior of two bio-climatic indexes and statistical characteristics of the air quality index for Sofia city - the capital of Bulgaria for the period 2008 - 2014. The study is based on WRF-CMAQ model system simula-tions with a spatial resolution of 1 kilometer. The air quality is estimated by the air quality index, taking into account the influence of different pollutants and the thermal conditions by two indi-ces, respectively, for hot and cold weather. Results: It was found that half of the heat and cold index categories are present in the simulations. Their distribution has some spatial features. All air quality categories are present in the domain, with dominance only of the O3 and PM10. Conclu-sions: It was found that Sofia is not so hot and air polluted place, but in some situations, people have to have some concerns when intend to be outdoors for a prolonged time.

The building sector is the largest consumer of energy and there are still major scientific challenges in this field. The façade, being the interface between the exterior and interior space, plays a key role in the energy efficiency of a building. In this context, this paper focuses on a ventilated bioclimatic wall for NZEB zero energy buildings. The objective of this study is to investigate an experimental set-up based on a Hot Box allowing characterizing the thermal performances of the ventilated wall. A specific ventilated prototype and an original thermal metrology has been developed. This paper presents the ventilated prototype, the experimental set-up and experimental results on the thermal performances of the ventilated wall. The influence of the air space thickness and the air flow rate on the thermal performances of the ventilated wall is studied.