COMMUNICATION
|
doi:10.20944/preprints202201.0108.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Acinetobacter baumannii; antimicrobial resistance; circular dichroism spectroscopy; efflux protein; efflux pump; foodborne pathogen; hospital-acquired infection; polyamine
Online: 10 January 2022 (12:19:07 CET)
ARTICLE
|
doi:10.20944/preprints202112.0453.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
anti-citrullinated protein antibody (ACPA); alpha-1-antitrypsin (A1AT); DBA/1JJmsSlc mice Proteome analysis; rheumatoid arthritis (RA)
Online: 28 December 2021 (14:44:54 CET)
ARTICLE
|
doi:10.20944/preprints202112.0075.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Sex chromosomes; Hill-Robertson interference; male-driven molecular evolution; pseudoautosomal region; pseudogenes; purifying selection; protein structure; Psittaciformes
Online: 6 December 2021 (13:21:10 CET)
BRIEF REPORT
|
doi:10.20944/preprints202105.0526.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
SARS-CoV-2 virus; complete genome sequencing; COVID-19 RT-PCR testing; Spike protein; vi-ral variants
Online: 21 May 2021 (15:12:17 CEST)
ARTICLE
|
doi:10.20944/preprints202003.0046.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
AT-hook motif nuclear protein 18; AHL18; At3G60870; Arabidopsis; Lateral root development; Root apical meristem; Cell proliferation
Online: 4 March 2020 (04:40:34 CET)
REVIEW
|
doi:10.20944/preprints202001.0030.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
histone deacetylase 6 inhibitor; personalized treatment; heat shock protein 90α; leukemia stem cells; imatinib resistance; targeted therapy
Online: 4 January 2020 (06:18:22 CET)
ARTICLE
|
doi:10.20944/preprints201910.0358.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
epithelial-to-mesenchymal transition; TGF-β1; cAMP; A-kinase anchoring protein; Ezrin; AKAP95; Yotiao; cigarette smoke; COPD
Online: 31 October 2019 (02:15:56 CET)
ARTICLE
|
doi:10.20944/preprints202406.1145.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
group-specific component protein-derived macrophage-activating factor; RAW264.7 macrophages; M1/M2 macrophages; macrophage polarization; anti-tumor effects
Online: 17 June 2024 (12:43:17 CEST)
ARTICLE
|
doi:10.20944/preprints202405.0243.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Alzheimer’s disease; amyloid precursor protein; cerebral organoid; disease modeling; drug screening; induced pluripotent stem cells; organoids; tau pathology
Online: 6 May 2024 (07:37:30 CEST)
REVIEW
|
doi:10.20944/preprints202403.1722.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Immunometabolite; Mitochondria-derived metabolite; Itaconate; Aconitate; Fumarate; Reactive metabolite; Electrophile signaling; Protein profiling
Online: 28 March 2024 (08:49:17 CET)
ARTICLE
|
doi:10.20944/preprints202403.1512.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
biosorption; CARD; cucurbitacins; cuticles; farneslation; isoprenylation; Meloidogyne enterolobii; total protein
Online: 26 March 2024 (13:09:18 CET)
ARTICLE
|
doi:10.20944/preprints202403.1501.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
NanoLuc; PII; NtcA; nitrogen regulation; energy regulation; Protein-fragment complementation assays; PCAs; complementation reporter; environmental factors; 2-oxoglutarate
Online: 26 March 2024 (08:07:45 CET)
ARTICLE
|
doi:10.20944/preprints202401.1736.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
immunogenetics; immunogenic peptides; pathogenic organism; vertebrate host; computational models; protein structure; T-cell receptor; adaptive immunity; deep learning.
Online: 24 January 2024 (11:05:53 CET)
ARTICLE
|
doi:10.20944/preprints202311.0276.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
chronic mild stress; depression; imipramine; heat shock protein; HSP90; inducible HSP90A; constitutive HSP90B; HSP70; inducible HSP72; constitutive HSC70
Online: 6 November 2023 (11:35:13 CET)
ARTICLE
|
doi:10.20944/preprints202310.1181.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
recombinant probiotic -based vaccines; probiotic strain E. faecium L3; mucosal vaccines; SARS-CoV-2 spike protein; vaccine efficacy.
Online: 18 October 2023 (11:29:09 CEST)
ARTICLE
|
doi:10.20944/preprints202306.0357.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Cardiomyopathy; myosin RLC; myosin ELC; N-terminal protein modification, S15D-RLC phosphomimetic, super-relaxed state (SRX); Tg mice
Online: 5 June 2023 (16:43:56 CEST)
REVIEW
|
doi:10.20944/preprints202305.1895.v2
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
lipid membrane; excitable cells; synaptic vesicles; H+ ion; Ca2+ signaling; calcium; binding proteins; signal transduction; G-protein coupled receptors
Online: 6 June 2023 (10:53:32 CEST)
ARTICLE
|
doi:10.20944/preprints202304.1265.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
amyloid bodies; intrinsically disordered protein; liquid-liquid phase separation; membrane-less organelle; nuclear stress bodies; nucleolar biomolecular condensates
Online: 30 April 2023 (05:18:24 CEST)
ARTICLE
|
doi:10.20944/preprints202212.0572.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
formate dehydrogenase; Candida boidinii; protein engineering; X-ray crystallography; structural biology; structural dynamics; Turkish Light Source; Turkish DeLight.
Online: 30 December 2022 (08:03:07 CET)
ARTICLE
|
doi:10.20944/preprints202211.0362.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Arf-like protein 2 (ARL2); tubulin αβ-heterodimers; retina; rod photoreceptors; microtubule cytoskeleton (MTC); dynein heavy chain (DYNC1H1)
Online: 21 November 2022 (02:50:04 CET)
BRIEF REPORT
|
doi:10.20944/preprints202208.0474.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
prenatal infection; virome; viral antibody; VirScan; ViroCap; maternal viral infection; viral protein; GBV-C; placenta; fetal viral infection
Online: 29 August 2022 (08:07:37 CEST)
ARTICLE
|
doi:10.20944/preprints202203.0029.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
blood component removal; C-reactive protein; CRP apheresis; COVID-19; multiple organ fail-ure; pulmonary fibrosis; SARS virus
Online: 2 March 2022 (02:34:23 CET)
ARTICLE
|
doi:10.20944/preprints202109.0333.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
small RNA Oxys; RNA chaperone Hfq protein; gene expression regulator; molecular dynamics simulations; binding free energy; interaction entropy
Online: 20 September 2021 (12:47:28 CEST)
ARTICLE
|
doi:10.20944/preprints202102.0494.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Latent membrane protein 1; Epstein-Barr virus; Herpesvirus; Proteomics; Mass spectrometry; interactions; signaling; extracellular vesicles; exosomes; CD63; Tetraspanin
Online: 22 February 2021 (16:27:27 CET)
REVIEW
|
doi:10.20944/preprints202101.0458.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
blood-brain barrier; transient receptor potential cation channels; ischemic stroke; neuroprotection; calcium signaling; cAMP response element-binding protein
Online: 25 January 2021 (09:20:51 CET)
ARTICLE
|
doi:10.20944/preprints202012.0635.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Free fatty acid receptor 2; microbiota; metabolite; sensor; G-coupled protein receptor; signaling; Alzheimer’s disease; senescence; C. elegans
Online: 24 December 2020 (14:56:00 CET)
ARTICLE
|
doi:10.20944/preprints202012.0541.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
3D printing; biomimetic; poly (lactic acid); spheroids; bone repair; 3D printed scaffold; bone morphogenetic protein 2; biomimetic apatite.
Online: 21 December 2020 (16:48:39 CET)
REVIEW
|
doi:10.20944/preprints202012.0048.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
accessory protein; alternate reading frame; nomenclature; open reading frame; ORF3b; ORF3d; ORF9a; ORF9b; overlapping ORF; SARS-CoV-2
Online: 2 December 2020 (08:04:06 CET)
REVIEW
|
doi:10.20944/preprints202010.0488.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
mitochondrial carriers; SLC transporters; SLC25; MCF; SLC54; MPC; SLC55; LETM; SLC56; sideroflexin; ABC transporter; sequence analysis; protein targeting
Online: 23 October 2020 (11:00:09 CEST)
REVIEW
|
doi:10.20944/preprints202007.0448.v1
Subject:
Medicine And Pharmacology,
Obstetrics And Gynaecology
Keywords:
C-reactive protein; hs-CRP; albumins; Glasgow Prognostic Score; Endometrial Cancer; CRP to albumin ratio; CRP; Cancer; Inflammation
Online: 19 July 2020 (21:13:19 CEST)
ARTICLE
|
doi:10.20944/preprints202005.0407.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
SARS-CoV-2; spike protein; D614G mutation; genotype distribution; furin cleavage site; secondary structure; sequence analysis; homology modeling
Online: 24 May 2020 (20:31:16 CEST)
ARTICLE
|
doi:10.20944/preprints202005.0077.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
centromere protein F (CENPF); Estrogen Receptor beta; Lung Adenocarcinoma (LUAD); WGCNA package; non-small cell lung cancer (NSCLC)
Online: 5 May 2020 (12:08:59 CEST)
ARTICLE
|
doi:10.20944/preprints202004.0429.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Aging; Almond; Chlorogenic acid; Lipid peroxidation; Mitochondria; 8-Oxo-guanine; Oxidative stress; Protein carbonylation; Sirtuin; Superoxide dismutase; Yeast
Online: 24 April 2020 (08:54:52 CEST)
ARTICLE
|
doi:10.20944/preprints202004.0243.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
vitamin C; ascorbic acid; ascorbate; pneumonia; community acquired pneumonia; oxidative stress; protein carbonyls; hypovitaminosis C; vitamin C deficiency
Online: 15 April 2020 (10:12:26 CEST)
ARTICLE
|
doi:10.20944/preprints201912.0374.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
alpha-fetoprotein; estrogens; selective estrogen receptor modulators; homology-based modeling; molecular docking; protein-ligand interaction; amino acid substitutions
Online: 29 December 2019 (08:08:23 CET)
ARTICLE
|
doi:10.20944/preprints201910.0161.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Enterovirus 71; EV71; EV71 non-structural protein 2B; interleukin enhancer binding factor 2; ILF2; virus infection; virus replication
Online: 15 October 2019 (05:37:34 CEST)
ARTICLE
|
doi:10.20944/preprints201908.0182.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
indirubin-3′-monoxime; p53; death receptor 5; TNF-related apoptosis-inducing ligand; transcription factor C/EBP homologous protein
Online: 17 August 2019 (04:19:38 CEST)
ARTICLE
|
doi:10.20944/preprints201609.0001.v1
Subject:
Medicine And Pharmacology,
Orthopedics And Sports Medicine
Keywords:
protein-disulfide isomerase-associated 3; osteoarthritis; extracorporeal shockwave therapy; 1α,25-Dihydroxyvitamin D3 signaling pathway; two dimensional electrophoresis
Online: 1 September 2016 (10:47:39 CEST)
ARTICLE
|
doi:10.20944/preprints202401.2061.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
SARS-CoV-2; Angiotensin-converting enzyme 2 (ACE2); Spike protein; Traditional Chinese medicine; Scutellaria baicalensis; Baicalein; Baicalin
Online: 31 January 2024 (02:00:26 CET)
ARTICLE
|
doi:10.20944/preprints202309.1867.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
vitamin C; ascorbic acid; diabetes; diabetes mellitus; body weight; C-reactive protein; dietary intake; dietary requirements; NHANES; EPIC-Norfolk
Online: 28 September 2023 (03:52:33 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0113.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
Post-Acute COVID-19 Vaccination Syndrome; PACVS, G-protein-coupled receptor; receptor antibody; interleukin-6; dis-autonomy; chronic fatigue.
Online: 4 September 2023 (07:14:41 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0429.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
thrombosis; kinetic parameters; cell growth; protein purification; biomass production; Chlorophyceae; agro-industrial sub-product; extraction methods; molecular weight; chromatography
Online: 4 August 2023 (10:49:13 CEST)
ARTICLE
|
doi:10.20944/preprints202307.1790.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Spike protein; B-cell epitope mapping; COVID-19; DENV; SARS-CoV-2 variants; Vaccination; Cross-reactivity; Antibody-mediated enhancement.
Online: 26 July 2023 (09:41:31 CEST)
REVIEW
|
doi:10.20944/preprints202307.1599.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
pregnancy associated plasma protein-A; breast cancer; triple negative breast cancer; epithelial-mesenchymal transition; cancer therapy; cancer biomarker; immunotherapy
Online: 24 July 2023 (10:35:57 CEST)
ARTICLE
|
doi:10.20944/preprints202305.2251.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
durum wheat pasta; by-products; zero-waste; plant protein sources; pepper seeds; pepper placenta; tomato waste; amino acids composition
Online: 31 May 2023 (13:02:32 CEST)
ARTICLE
|
doi:10.20944/preprints202304.1063.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
empagliflozin; vascular calcification; AMP-activated protein kinase; nuclear factor erythroid-2-related factor; heme oxygenase 1; chronic kidney disease
Online: 27 April 2023 (09:35:25 CEST)
BRIEF REPORT
|
doi:10.20944/preprints202212.0518.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
immunoassay; epitope coverage; quantitative antibody binding; protein microarray; SARS-CoV-2 antibodies; humoral response; SARS-CoV-2 re-infection
Online: 27 December 2022 (10:43:18 CET)
ARTICLE
|
doi:10.20944/preprints202210.0158.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
severe acute respiratory syndrome coronavirus 2; SARS-CoV-2; COVID-19; accessory protein; mapping; structure; Open reading frame, Orf.
Online: 3 November 2022 (10:27:01 CET)
ARTICLE
|
doi:10.20944/preprints202206.0010.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
COVID-19; ARDS; Cytokine Storm; Spike S1 protein; SARS-CoV-2, Long COVID; ACE2; A549 cells; Caco-2 cells
Online: 1 June 2022 (09:49:27 CEST)
ARTICLE
|
doi:10.20944/preprints202205.0336.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Long non-coding RNA; Prostate androgen-regulated transcript 1; miR-204-3p; insulin-like growth factor binding protein 2
Online: 24 May 2022 (11:57:26 CEST)
REVIEW
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
Pangolin; Intrinsic; Disorder; Protein; Nucleocapsid; Virulence; Shell; Covid; Coronavirus; Vaccine; Immune; Antibody; Shell; Nucleoprotein; Matrix; Attenuate; Severe Acute Respiratory
Online: 4 May 2021 (16:24:51 CEST)
ARTICLE
|
doi:10.20944/preprints202103.0708.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Adolescents; high sensitivity C-reactive protein; Insulin-like growth factor binding proteins; Obesity; Oxidized Low-Density Lipoprotein; Predictive diagnostics
Online: 29 March 2021 (16:33:20 CEST)
ARTICLE
|
doi:10.20944/preprints202102.0001.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Giant cell arteritis; anterior ischemic optic neuropathy; clinical prediction rule; diagnostic algorithm; C-reactive protein; temporal compression sonography; ultrasound
Online: 1 February 2021 (08:44:33 CET)
ARTICLE
|
doi:10.20944/preprints202101.0149.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Apolipoprotein E (ApoE); microtubule associated protein (MAPT); synuclein alpha (SNCA); eQTL; TOMM40; KANSL1; mitochondria; Parkinson’s Progression Markers Initiative (PPMI)
Online: 8 January 2021 (11:45:19 CET)
REVIEW
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
SARS-CoV-2; S-protein; RBD; COVID-19; neutralizing antibodies; serology; T-cells; vaccines; animal models; Operation Warp Speed
Online: 27 October 2020 (11:25:32 CET)
ARTICLE
|
doi:10.20944/preprints202004.0171.v2
Subject:
Biology And Life Sciences,
Virology
Keywords:
protein functional domains; short linear motifs; coronaviruses; COVID-19; severe acute respiratory syndrome-related coronavirus; 2019-nCoV; virus outbreak
Online: 16 May 2020 (18:54:17 CEST)
ARTICLE
|
doi:10.20944/preprints202004.0390.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
SARS-CoV-2; COVID-19; SARS-CoV; ACE2; spike protein; phosphorylation; O-β-GlcNAcylation; molecular docking; chloroquine; 2-hydroxybenzohydrazine
Online: 22 April 2020 (06:01:00 CEST)
ARTICLE
|
doi:10.20944/preprints201911.0131.v1
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
epitope; monoclonal antibodies; open reading frame 3 protein; apoptosis; p53; porcine circovirus type 2; thimerosal; interfere; antibody binding; lymphocyte
Online: 12 November 2019 (16:20:27 CET)
ARTICLE
|
doi:10.20944/preprints201910.0302.v1
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
phylogenomics; protein structure; secondary structure; relative solvent accessibility CAT model; non-stationary models; RY coding; metazoan phylogeny; ctenophora; porifera
Online: 27 October 2019 (11:00:50 CET)
ARTICLE
|
doi:10.20944/preprints201909.0324.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
immunotherapy; human hepatoma cells; programmed cell death protein 1 (pd-1); magnetic nanoparticles; peptide-imprinted polymer; natural killer cells
Online: 29 September 2019 (05:28:46 CEST)
REVIEW
|
doi:10.20944/preprints201909.0218.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
M-type phospholipase A2; Thrombospondin type containing domain A7; Retinol-binding protein; Beta-2 microglobulin; membranous glomerulonephritis; neutral endopeptidase
Online: 19 September 2019 (04:59:36 CEST)
REVIEW
|
doi:10.20944/preprints201705.0135.v1
Subject:
Medicine And Pharmacology,
Dietetics And Nutrition
Keywords:
dietary substitution; CVD; saturated fatty acids; protein; monounsaturated fatty acids; polyunsaturated fatty acids; dairy fat; refined carbohydrates; whole grains
Online: 18 May 2017 (04:01:53 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0925.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
age-related amyloid, Congo red staining, constipation, epidermal growth factor-containing fibulin-like extracellular matrix protein 1, lower gastrointestinal tract
Online: 13 June 2024 (14:53:40 CEST)
ARTICLE
|
doi:10.20944/preprints202405.0647.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
SARS-CoV-2; COVID-19; Spike protein; Epistasis; Reverse transcription; Pathogenesis; Vaccine efficacy; Complementary DNA; Reverse transcription-polymerase chain reaction
Online: 10 May 2024 (11:30:40 CEST)
ARTICLE
|
doi:10.20944/preprints202311.0257.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
modular nanotransporters; Keap1E3 ligase; N-protein degradation; SARS-CoV-2 virus; flow cytometry; Western blot; intracellular concentrations; thermophoresis; cathepsin B
Online: 3 November 2023 (14:35:15 CET)
HYPOTHESIS
|
doi:10.20944/preprints202310.2100.v2
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Alzheimer’ s disease; Angiotensin II; Angiotensin-converting enzyme 2; COVID-19; Brain; Dementia; Furin; Neurological disorders; SARS-CoV-2; Spike protein
Online: 12 February 2024 (15:48:57 CET)
ARTICLE
|
doi:10.20944/preprints202308.2083.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
COVID-19; SARS-CoV-2 spike protein 1 (S1); methylglyoxal; MG-H1; Glyoxalase 1; RAGE; inflammation; Nrf2; BEAS-2B; A549
Online: 30 August 2023 (12:02:02 CEST)
REVIEW
|
doi:10.20944/preprints202308.0520.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
SARS-CoV-2; spike protein; mutations; viral infectivity; pathogenesis; vaccine efficacy; immune evasion; antibody neutralization; T-cell response; therapeutic targeting
Online: 7 August 2023 (10:12:28 CEST)
ARTICLE
|
doi:10.20944/preprints202306.0068.v1
Subject:
Medicine And Pharmacology,
Other
Keywords:
3D printed scaffolds; carbon nanotube; capped carbon nanotube; protein kinase A; pseudomonas elastase; exotoxin A; alpha-hemolysin; shiga toxin 2a
Online: 5 June 2023 (02:56:10 CEST)
REVIEW
|
doi:10.20944/preprints202301.0099.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Atg8; autophagic receptor; Cue5; SAR; selective autophagy; selective autophagy receptor; ubiquitin; ubiquitin-binding domain; ubiquitin-binding protein; ubiquitin-binding receptor
Online: 5 January 2023 (04:33:12 CET)
ARTICLE
|
doi:10.20944/preprints202111.0558.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Yersinia pestis; vaccine; guinea pigs; bubonic plague; inactivated vaccine; phage; bacterial ghost; protection; protein-E-mediated lysis, holin-endolysin system
Online: 30 November 2021 (11:08:18 CET)
REVIEW
|
doi:10.20944/preprints202109.0501.v2
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Antigen Selection; Epitope Selection; Antibody Targeting; Epitope Accessibility; Antibody Engineering; Protein Engineering; Drug Targeting; Model-Informed Drug Discovery and Development
Online: 3 November 2021 (08:26:47 CET)
ARTICLE
|
doi:10.20944/preprints202107.0295.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
SARS-CoV-2 spike protein; ACE2 host receptor; nanobodies; molecular dynamics; mutational sensitivity; binding free energy; allosteric interactions; signal transmission
Online: 13 July 2021 (11:18:02 CEST)
ARTICLE
|
doi:10.20944/preprints202106.0553.v1
Subject:
Engineering,
Bioengineering
Keywords:
Iron-oxide nanoparticles, primary-secondary method, diagnostics of cancer, A549 cell line, transferrin protein receptors, adenocarcinoma, biotin-streptavidin, biotinylated antibodies
Online: 23 June 2021 (09:17:59 CEST)
ARTICLE
|
doi:10.20944/preprints202103.0059.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Metallothionein (MT); Scientific discovery; Scientific pursuit; Research strategies; upward looking research; Exploratory research; Protein function; Compensation; Moonlighting; multifunctional proteins; Vestiges
Online: 2 March 2021 (09:39:39 CET)
ARTICLE
|
doi:10.20944/preprints202102.0296.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
End-Stage Renal Disease, Chronic Kidney Disease, Wnt-Pathway, R-Spondin 1, β-Catenin, Dickkopf-Related Protein 1, and Sclerostin.
Online: 12 February 2021 (10:08:22 CET)
ARTICLE
|
doi:10.20944/preprints202002.0148.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cell stress response; stressome; extracellular vesicle; heat shock protein 90 (HSP90); cell division control 37 (CDC37); prostate cancer; exosome; ectosome
Online: 11 February 2020 (14:50:14 CET)
ARTICLE
|
doi:10.20944/preprints201911.0399.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
olivo-ponto-cerebellar atrophy (OPCA); Purkinje cells; Calcium/calmodulin dependent protein kinase II (CAMK2); Plastin (Fimbrin); Hirano bodies; Huntington’s disease
Online: 30 November 2019 (14:47:30 CET)
ARTICLE
|
doi:10.20944/preprints201910.0283.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
chronic inflammation; biomarker panels; leukocyte count; C-reactive protein; related syndromes and pathologies; risk assessment; screening programmes; ageing; elderly's health
Online: 25 October 2019 (04:16:43 CEST)
REVIEW
|
doi:10.20944/preprints201811.0268.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
mitochondria; stress response; mitophagy; mitochondrial dynamics; mitochondrial unfolded protein response (UPRmt); quality control; prohibitins; PHB complex; PHB-1; PHB-2
Online: 12 November 2018 (05:23:36 CET)
REVIEW
|
doi:10.20944/preprints201810.0204.v2
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
DNA origami; aptamer; DNA nanotechnology; protein nano array; biosensor; logic gate; enzyme cascade; drug delivery system; targeted therapy; molecular robotics
Online: 22 October 2018 (10:57:21 CEST)
REVIEW
|
doi:10.20944/preprints201809.0040.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
Triggering receptor expressed on myeloid cells, DNAX-activating protein 12, cardiovascular diseases, atherosclerosis, coronary arteries diseases, acute myocardial infract, endocarditis
Online: 3 September 2018 (14:50:17 CEST)
ARTICLE
|
doi:10.20944/preprints201808.0298.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Heterodimeric G protein coupled receptor; saturation transfer difference nuclear magnetic resonance spectroscopy; differential scanning calorimetry; circular dichroism; intrinsic fluorescence spectroscopy
Online: 17 August 2018 (11:15:39 CEST)
ARTICLE
|
doi:10.20944/preprints202407.1889.v1
Subject:
Medicine And Pharmacology,
Emergency Medicine
Keywords:
Bowel obstruction; Emergency surgery; Machine learning; Postoperative complications; Artificial intelligence; Risk prediction; C-reactive protein; Malignant obstruction; K-nearest neighbors algorithm
Online: 24 July 2024 (12:38:09 CEST)
ARTICLE
|
doi:10.20944/preprints202407.0097.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
advanced glycation end products (AGEs); metabolic dysfunction; protein relation structure-function; spectroscopic analysis; conformational changes; catalytic aging; molecular wear; enzymatic rescue
Online: 2 July 2024 (02:28:47 CEST)
ARTICLE
|
doi:10.20944/preprints202404.0469.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
Alzheimer’ s disease; amyloid β peptide; human serum albumin; low-molecular-weight ligand; protein-ligand interaction; surface plasmon resonance spectroscopy
Online: 7 April 2024 (10:18:10 CEST)
REVIEW
|
doi:10.20944/preprints202404.0089.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
bacterial nucleoid; phase-contrast microscopy; DNA polymer physics; protein depletion; chromosome arms; replication bubble or orisome; active and passive DNA segregation.
Online: 1 April 2024 (13:11:12 CEST)
ARTICLE
|
doi:10.20944/preprints202312.0522.v1
Subject:
Biology And Life Sciences,
Aquatic Science
Keywords:
liver histology; liver index; sustainable feed; poultry by-product meal; Hermetia illucens meal; plant-protein; lipid metabolism; fish welfare; blood biochemistry
Online: 7 December 2023 (11:57:53 CET)
REVIEW
|
doi:10.20944/preprints202310.1640.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Tracer development; neuroinflammation; pneumonia; myocarditis; translocator protein (TSPO); cyclooxygenase-2 (COX-2); positron emission tomography (PET); single-photon emission tomography (SPECT)
Online: 25 October 2023 (11:31:31 CEST)
REVIEW
|
doi:10.20944/preprints202309.2000.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Cluster of differentiation 74 (CD74); oncogenic fusion protein; fusion gene; CD74-ROS1; CD74-NTRK1; CD74-NRG1; CD74-NRG2a; CD74-PDGFRB; cancer.
Online: 29 September 2023 (04:35:12 CEST)
ARTICLE
|
doi:10.20944/preprints202307.1289.v1
Subject:
Chemistry And Materials Science,
Food Chemistry
Keywords:
salmon analog; caviar analog; plant-based foods; voltammetry; glassy carbon electrode; antioxidant capacity; 3D printing; isoflavones; isolated soy protein; white beans
Online: 19 July 2023 (09:51:58 CEST)
REVIEW
|
doi:10.20944/preprints202205.0037.v1
Subject:
Medicine And Pharmacology,
Dermatology
Keywords:
Melanoma; Chemo-thermo-immuno-therapy; Melanogenesis; Magnetite nanoparticle; Drug delivery system; Heat shock protein; In situ vaccine therapy; Immune checkpoint inhibitor
Online: 5 May 2022 (12:23:27 CEST)
REVIEW
|
doi:10.20944/preprints202110.0005.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
Brown adipose tissue; beige adipose tissue; obesity; cold exposure; uncoupling protein-1, beta-adrenergic receptor; energy expenditure; adipose browning; micro-RNA
Online: 1 October 2021 (11:30:39 CEST)
ARTICLE
|
doi:10.20944/preprints202106.0393.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
clear cell renal cell carcinoma (ccRCC); LOX-1 protein; volatile compounds (VOCs); prognostic biomarker; urine; gas chromatography mass spectrometer (GC/MS)
Online: 15 June 2021 (10:29:39 CEST)
ARTICLE
|
doi:10.20944/preprints202010.0274.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
protein aggregation; inhibition of amyloid fibril formation; antioxidants; polyphenols; cystatin C; NAC and vitamin C; amyloid fibrils; stefin B aggregation; TEM
Online: 13 October 2020 (10:49:14 CEST)
ARTICLE
|
doi:10.20944/preprints202008.0632.v1
Subject:
Computer Science And Mathematics,
Mathematical And Computational Biology
Keywords:
Blockchain; P2P Networks; Nucleobase DNA/RNA sequence; Gene Expression; Cell Population; Epigenetics; Methylation; Consensus; Hash Algorithm; Triple Codons; Protein Synthesis; Cryptocurrency
Online: 28 August 2020 (10:33:42 CEST)
ARTICLE
|
doi:10.20944/preprints202002.0234.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
adeno-associated virus; protein sequence analysis; overlapping genes; amino acid depletion; cysteine depletion; tyrosine depletion; capsid design; membrane-binding amphipathic helix
Online: 17 February 2020 (02:42:39 CET)
ARTICLE
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Mediator: stress; MCHM; Med15; Snf1; polyQ; protein chaperone; master variator; intrinsically disordered regions; yeast; hydrotrope; transcription factors; Myc tag; inorganic phosphate
Online: 3 February 2020 (13:37:07 CET)
REVIEW
|
doi:10.20944/preprints201908.0186.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
heat shock protein (HSP); extracellular vesicle (EV); exosome; oncosome; immune evasion; resistance-associated secretory phenotype (RASP); EMT; hypoxia; biomarker; liquid biopsy
Online: 17 August 2019 (16:15:01 CEST)
ARTICLE
|
doi:10.20944/preprints201804.0079.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Alzheimer’s disease (AD); amyloid precursor protein (APP); familial AD (FAD); sporadic AD (SAD); BACE1 inhibitors; APP-independent generation of beta amyloid
Online: 6 April 2018 (15:16:08 CEST)