REVIEW
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
hyperoxaluria; oxalate; inhibitor; small molecule drug; glycolate oxidase; lactate dehydrogenase; liver selective distribution
Online: 31 December 2020 (08:59:47 CET)
ARTICLE
|
doi:10.20944/preprints202012.0588.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Trazodone; drug design; dissolution; crystal structure; solid-state NMR (SSNMR) spectroscopy; GIPAW calculation
Online: 23 December 2020 (13:42:36 CET)
ARTICLE
|
doi:10.20944/preprints202011.0748.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Keywords: Brimonidine; Laponite; drug delivery; glaucoma; nanomedicine; monitoring; optical coherence tomography; vitreous; intravitreal.
Online: 30 November 2020 (20:25:24 CET)
ARTICLE
|
doi:10.20944/preprints202011.0512.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
antimicrobials; meropenem; generic drug; real-life studies; product surveillance, postmarketing; treatment outcome; pharmacovigilance
Online: 19 November 2020 (13:34:26 CET)
ARTICLE
|
doi:10.20944/preprints202011.0292.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Alzheimer's disease; BACE1; Molecular dynamics; MM/GBSA; Inhibitors; Drug likeness; Ligand efficiency, Kd.
Online: 10 November 2020 (09:10:50 CET)
ARTICLE
|
doi:10.20944/preprints202010.0032.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
Nanomedicine; human ferritin; gastrointestinal tumors; non-camptothecin topoisomerase I inhibitors; drug-delivery; CD71
Online: 2 October 2020 (09:21:53 CEST)
REVIEW
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
apoptosis; antitumor; antimetastasis; anti-angiogenesis; NK-1 receptor; substance P; drug repositioning; Emend
Online: 31 August 2020 (10:11:13 CEST)
REVIEW
|
doi:10.20944/preprints202008.0312.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
SARS-CoV-2(COVID-19); + ssRNA; ribosomal – framshift; Pseudoknot; replication; model; drug; vaccine
Online: 14 August 2020 (08:26:31 CEST)
ARTICLE
|
doi:10.20944/preprints202007.0424.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
4-Phenylbutyric acid; Colon-targeted drug delivery; Colitis; Prodrug; ER stress; Chemical chaperone
Online: 19 July 2020 (19:15:20 CEST)
REVIEW
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
nucleoid-associated proteins (NAPs); moonlighting proteins; drug target; biofilm; specificity determination; phylogenetic analysis
Online: 7 June 2020 (09:07:56 CEST)
REVIEW
|
doi:10.20944/preprints202005.0342.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
seaweed; metabolites; neuroprotection; Alzheimer’s disease; Parkinson’s disease; ischemic stroke; computer-aided drug discovery
Online: 21 May 2020 (09:49:29 CEST)
REVIEW
|
doi:10.20944/preprints201912.0179.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
globular set; category theory; multidimensional; visual recognition; drug-resistant epilepsy; transcranial magnetic stimulation.
Online: 13 December 2019 (10:37:03 CET)
ARTICLE
|
doi:10.20944/preprints201911.0024.v1
Subject:
Computer Science And Mathematics,
Information Systems
Keywords:
Iranian traditional medicine; Persian medicine; ontology; knowledge-base; Mizaj; temperament; new drug discovery
Online: 3 November 2019 (17:07:50 CET)
ARTICLE
|
doi:10.20944/preprints201908.0253.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
halogen bonding; fluorine; iodine; pentafluorosulfanyl; titration; ab initio calculation; NMR study; drug design
Online: 25 August 2019 (15:41:59 CEST)
ARTICLE
|
doi:10.20944/preprints201803.0144.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
sea anemone; drug discovery; cancer; antiangiogenic; endothelial cells; RGD motif; Kunitz type inhibitor
Online: 19 March 2018 (08:15:38 CET)
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
oleanolic acid derivatives; synthesis; anti-tumor activity; molecular docking; computer-aided drug design
Online: 24 April 2017 (12:08:36 CEST)
ARTICLE
|
doi:10.20944/preprints202408.0458.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
MRI visualization; combination therapy; multi-drug delivery platform; magnetotactic bacterial; enhanced photothermal-chemodynamic therapy
Online: 8 August 2024 (04:27:55 CEST)
ARTICLE
|
doi:10.20944/preprints202407.1735.v1
Subject:
Computer Science And Mathematics,
Probability And Statistics
Keywords:
drug safety; association rule mining; Apriori; safety data; disproportionality measures; pharmacovigilance; co-occurrence analysis
Online: 22 July 2024 (17:35:47 CEST)
ARTICLE
|
doi:10.20944/preprints202405.0380.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
thiocarbohydrazones; Schiff base; moleculer docking; urease inhibition; pharmacokinetic properties; drug combinations
Online: 8 May 2024 (02:40:50 CEST)
REVIEW
|
doi:10.20944/preprints202404.1839.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
Omega-3 fatty acids; cardiovascular disease; Nanoparticle encapsulation; Metal-organic framework; Drug delivery systems
Online: 28 April 2024 (08:33:48 CEST)
ARTICLE
|
doi:10.20944/preprints202404.1209.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Mycobacterium tuberculosis; Drug Resistance; Whole Genome Sequencing; Genetic Diversity; Brazil; Novel Mutations
Online: 18 April 2024 (07:51:01 CEST)
ARTICLE
|
doi:10.20944/preprints202404.0426.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
CDK8; Cyclin C; Protein-protein interaction; Molecular dynamic simulation; Free energy calculation; Drug design
Online: 5 April 2024 (10:12:16 CEST)
ARTICLE
|
doi:10.20944/preprints202404.0199.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
follicular thyroid neoplasia; PAX8– PPARγ fusion; fusion protein; structure-based drug design
Online: 3 April 2024 (07:24:16 CEST)
REVIEW
|
doi:10.20944/preprints202403.1716.v1
Subject:
Biology And Life Sciences,
Other
Keywords:
Adjuvant; Archaeal carriers; Lipid-based drug delivery; Vaccine delivery; Gene therapy; Immune modulators; Tocosome
Online: 28 March 2024 (09:47:09 CET)
ARTICLE
|
doi:10.20944/preprints202401.0661.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Protozoan diseases; Drug repurposing; Cytotoxicity; Dihydrofolate reductase inhibitors; Potassium (K+) channel blocker; ADME properties
Online: 9 January 2024 (10:30:36 CET)
REVIEW
|
doi:10.20944/preprints202401.0079.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
NF-E2-related factor 2; Drug resistance; Reactive oxygen species; Autophagy; Unfolded protein response
Online: 3 January 2024 (02:26:23 CET)
ARTICLE
|
doi:10.20944/preprints202311.1667.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
α-MSH; melanoma; peptide-drug conjugates; in vitro antiproliferative effect; in vivo antitumor activity
Online: 27 November 2023 (08:49:52 CET)
ARTICLE
|
doi:10.20944/preprints202311.1319.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
HIV; AIDS; drug use; sexually transmitted diseases; alcohol; female sex workers; FSWs
Online: 21 November 2023 (13:17:51 CET)
COMMUNICATION
|
doi:10.20944/preprints202311.1268.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
SARS-CoV-2; COVID-19; RdRp; m1A triphosphate; Antiviral Drug
Online: 21 November 2023 (07:19:23 CET)
ARTICLE
|
doi:10.20944/preprints202310.0980.v1
Subject:
Chemistry And Materials Science,
Surfaces, Coatings And Films
Keywords:
microparticles; scalable manufacturing; laser cutting; drug delivery; complex structures; composites; core-shell; defined size
Online: 16 October 2023 (16:53:55 CEST)
ARTICLE
|
doi:10.20944/preprints202309.1917.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Mycobacterium; Antibiotic resistance; Drug re-purposing; MbtA; Siderophores; Molecular Docking; Molecular Dynamics; PCA analysis
Online: 28 September 2023 (13:28:39 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0069.v1
Subject:
Public Health And Healthcare,
Health Policy And Services
Keywords:
MSM; trends; high-risk sexual behaviors; HIV; sexualized drug use; chemsex; sexually transmitted infections
Online: 4 September 2023 (02:43:27 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0011.v1
Subject:
Medicine And Pharmacology,
Anesthesiology And Pain Medicine
Keywords:
immunoassay; urine drug test; opioid; nonmedical; cancer pain; safety-net hospital; palliative medicine; education
Online: 1 September 2023 (04:02:26 CEST)
REVIEW
|
doi:10.20944/preprints202308.1747.v1
Subject:
Medicine And Pharmacology,
Transplantation
Keywords:
kidney transplantation; immunosuppression; adverse drug event; nephrotoxicity; NODAT; anemia; leukopenia; viral reactivation; hypertension; dyslipidemia
Online: 24 August 2023 (13:34:38 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0468.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
dasatinib; imatinib; nilotibin; ponatinib; children; therapeutic drug monitoring; sex and gender pharmacology; personalized medicine.
Online: 7 August 2023 (11:53:12 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0141.v1
Subject:
Chemistry And Materials Science,
Materials Science And Technology
Keywords:
A549 lung cancer; nanoparticles; cell-penetration, drug affinity, dissociation constants; molecular docking; antibacterial; hydroxychloroquine
Online: 2 August 2023 (04:54:14 CEST)
REVIEW
|
doi:10.20944/preprints202308.0109.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
preclinical; oncology; 3D culture; organ-on-a-chip; spheroid; organoid; 3D bioprinting; drug screening
Online: 2 August 2023 (02:48:00 CEST)
REVIEW
|
doi:10.20944/preprints202306.1209.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
End-stage renal disease; medication review; drug-related problems; negative outcomes associated with medication.
Online: 16 June 2023 (10:13:13 CEST)
REVIEW
|
doi:10.20944/preprints202305.0945.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Systems Pharmacology; Polypharmacology; Adverse Events; Drug Discovery; Functional genomics; Disease Modeling; Network analysis; Innovation
Online: 12 May 2023 (12:18:59 CEST)
ARTICLE
|
doi:10.20944/preprints202301.0221.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
Ion channels; Membrane proteins; Transmembrane proteins; Drug discovery; Protein language models; Convolutional Neural Network
Online: 12 January 2023 (09:21:08 CET)
REVIEW
|
doi:10.20944/preprints202210.0347.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
monkeypox virus; infection; treatment; antiviral; drug; management; public health emergency; tecovirimat; cidofovir; bibliometric analysis
Online: 24 October 2022 (03:38:12 CEST)
REVIEW
|
doi:10.20944/preprints202207.0031.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
Cell-state transitions; Phenotypic plasticity; Cancer Stem Cells; Intratumoral heterogeneity; Lamarckian Induction; Drug resistance
Online: 4 July 2022 (04:56:00 CEST)
ARTICLE
|
doi:10.20944/preprints202201.0082.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
breast cancer; cancer stem cell; therapy resistance; cationic amphiphilic drug; lysosome-dependent cell death
Online: 6 January 2022 (11:51:28 CET)
ARTICLE
|
doi:10.20944/preprints202112.0446.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
sleep breathing disorders; mandibular advancement; MAD; titratable positioner; drug-induced sleep endoscopy; patient selection.
Online: 28 December 2021 (11:03:45 CET)
REVIEW
|
doi:10.20944/preprints202110.0450.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
Fibrosis; Integrin; TGFβ; Therapeutic target; Drug; Inhibitor; Monoclonal antibody; α8β1; α11β1; Hepatic stellate cell
Online: 29 October 2021 (10:16:13 CEST)
ARTICLE
|
doi:10.20944/preprints202108.0512.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
oyster mushroom (Pleurotus sp.); PARP protein; 4UND protein; molecular docking; PyRx; BIOVIA drug discovery
Online: 26 August 2021 (16:15:06 CEST)
REVIEW
|
doi:10.20944/preprints202107.0650.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
chronic disorders; inflammation; human superorganism; holobiont; microbiome; multimorbidity; microimmunosome; polypharmacy; drug safety; sustainable healthcare
Online: 29 July 2021 (11:37:20 CEST)
ARTICLE
|
doi:10.20944/preprints202011.0307.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
TiO2 nanoparticles; antibacterial activity; multi-drug-resistance pathogens; MRSA; E. coli. P. aeruginosa; genotoxicity
Online: 10 November 2020 (12:09:17 CET)
ARTICLE
|
doi:10.20944/preprints202008.0667.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Ovarian cancer; drug resistance; apoptosis; proteomics; combination; cytotoxicity; artemisinin; oleanolic acid; platinum drugs; cisplatin
Online: 30 August 2020 (12:06:32 CEST)
ARTICLE
|
doi:10.20944/preprints202004.0369.v2
Subject:
Biology And Life Sciences,
Virology
Keywords:
COVID-19; SARS-CoV-2; spike protein; ACE1; ACE2; host-virus interaction; drug repurposing
Online: 2 August 2020 (09:23:18 CEST)
ARTICLE
|
doi:10.20944/preprints202005.0397.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
SARS-CoV-2; Drug repurposing; N-acetyl-D-glucosamine; ORF1ab; Biodata mining; Protein modelling
Online: 24 May 2020 (18:49:41 CEST)
REVIEW
|
doi:10.20944/preprints202002.0451.v1
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
systematic review; ADR assessment; elderly; aged-care facilities; medications monitoring; nursing home; drug review
Online: 29 February 2020 (03:41:22 CET)
ARTICLE
|
doi:10.20944/preprints202002.0071.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
2019-nCoV; novel corona virus; Wuhan virus; drug; vaccine; spike protein; epitope; vaccine design
Online: 5 February 2020 (15:34:15 CET)
ARTICLE
Subject:
Computer Science And Mathematics,
Mathematical And Computational Biology
Keywords:
c-src-tyrosine kinase; QSAR; molecular descriptors; virtual screening; drug discovery; cancer; molecular docking
Online: 25 October 2019 (11:21:43 CEST)
ARTICLE
|
doi:10.20944/preprints201909.0063.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
FABP4; A-FABP; aP2; antidiabetes; antiobesity; antiatherosclerosis; anticancer; computational tools; computer-aided drug discovery
Online: 5 September 2019 (15:39:58 CEST)
REVIEW
|
doi:10.20944/preprints201908.0271.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
GPCRs; membrane protein; molecular dynamics; protein structure; drug design; biased-signaling pathway; allosteric sites
Online: 26 August 2019 (15:34:57 CEST)
ARTICLE
|
doi:10.20944/preprints201811.0627.v1
Subject:
Chemistry And Materials Science,
Theoretical Chemistry
Keywords:
chemical space; chemical data set; chemoinformatics; consensus diversity plot; drug discovery; molecular diversity; visualization
Online: 30 November 2018 (10:06:15 CET)
ARTICLE
|
doi:10.20944/preprints201804.0374.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
STAT3 as a drug target; cyclic STAT3 decoy; oligodeoxynucleotide inhibitor; head and neck cancer
Online: 29 April 2018 (10:10:00 CEST)
ARTICLE
|
doi:10.20944/preprints201801.0136.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
polymer-drug association; inclusion nano-complex; an amphiphilic polymer; polysoaps; antibiotic resistance; ampicillin trihydrate
Online: 16 January 2018 (07:56:15 CET)
REVIEW
|
doi:10.20944/preprints201709.0050.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Alzheimer's-disease; dementia; drug targeting; nanoemulsion; neuroinflammation; oxidative stress; scavenger receptors; sonoporation; transcranial ultrasound
Online: 13 September 2017 (05:44:29 CEST)
REVIEW
|
doi:10.20944/preprints201705.0129.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
cell fate decision; cancer attractors; gene network dynamics; EMT; drug resistance; intrinsically disordered proteins
Online: 17 May 2017 (06:25:17 CEST)
CASE REPORT
|
doi:10.20944/preprints202408.0828.v1
Subject:
Emergency Medicine,
Medicine And Pharmacology
Keywords:
iliopsoas abscess; emergency department; multidisciplinary approach; drug-induced acute liver failure; critical care; personalized medicine
Online: 12 August 2024 (14:00:20 CEST)
REVIEW
|
doi:10.20944/preprints202405.1976.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Epileptogenesis; Neuroinflammation; Biomarkers; HMGB1; TNF-a; TLR-4; sTNFr2; CCL2; IL-33; Drug Resistant Epilepsy
Online: 30 May 2024 (04:05:12 CEST)
ARTICLE
|
doi:10.20944/preprints202405.1552.v1
Subject:
Chemistry And Materials Science,
Organic Chemistry
Keywords:
anabasine; cytisine; ureas; isoxazole; cytotoxic activity; antiproliferative activity; drug synergism; quantum chemical modeling molecular dockin
Online: 23 May 2024 (12:06:39 CEST)
ARTICLE
|
doi:10.20944/preprints202405.1100.v1
Subject:
Medicine And Pharmacology,
Anesthesiology And Pain Medicine
Keywords:
ibuprofen; diclofenac; celecoxib; membrane interaction; lipid composition; medium pH; drug concentration; analgesic activity; gastrointestinal toxicity
Online: 17 May 2024 (03:10:22 CEST)
REVIEW
|
doi:10.20944/preprints202404.0437.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
neurodegenerative diseases; Parkinson’ s disease; Alzheimer’ s disease; drug discovery; disease-modifying drugs
Online: 5 April 2024 (12:39:57 CEST)
REVIEW
|
doi:10.20944/preprints202403.0663.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
vault RNA; drug resistance; apoptosis; autophagy; cancer; aging; cellular metabolism; non-coding RNAs; cancer therapy
Online: 12 March 2024 (13:41:58 CET)
ARTICLE
|
doi:10.20944/preprints202403.0565.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
Two-dimensional liquid chromatography; heart-cutting 2D-LC; veterinary drug residue; nucleotides monophosphate; sheep’s milk
Online: 11 March 2024 (08:59:00 CET)
ARTICLE
|
doi:10.20944/preprints202402.0156.v1
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
antimicrobial resistance; biosecurity; dairy calves; ESBL E. coli; multi-drug resistant; waste milk
Online: 2 February 2024 (14:20:05 CET)
REVIEW
|
doi:10.20944/preprints202401.0524.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
transdermal drug delivery system; skin permeation; permeation enhancers; quality by design ap-proach; therapeutic applications
Online: 8 January 2024 (06:41:04 CET)
REVIEW
|
doi:10.20944/preprints202401.0156.v1
Subject:
Medicine And Pharmacology,
Reproductive Medicine
Keywords:
fertility preservation; ovarian hyperstimulation syndrome; gonadotropin-releasing hormone; quality of life; neoplasms; cryopreservation; drug therapy
Online: 3 January 2024 (07:50:49 CET)
REVIEW
|
doi:10.20944/preprints202312.0424.v1
Subject:
Chemistry And Materials Science,
Materials Science And Technology
Keywords:
nanoparticles; PLGA; Electrospinning; 3D printing; Techniques; bone regeneration, biomaterial, biocompatibility, biodegradability, bioactive molecules, drug delivery
Online: 7 December 2023 (01:35:39 CET)
ARTICLE
|
doi:10.20944/preprints202310.0546.v2
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
Candida auris; C. auris; Candida; Candidemia; Multi-drug resistant organism; MDRO; Emerging pathogens; Resistant pathogens
Online: 30 November 2023 (12:04:07 CET)
ARTICLE
|
doi:10.20944/preprints202310.1539.v1
Subject:
Computer Science And Mathematics,
Mathematical And Computational Biology
Keywords:
graph neural network; convolutional neural network; drug-target affinity; sequence and structural knowledge; heterogeneous models
Online: 25 October 2023 (08:23:34 CEST)
REVIEW
|
doi:10.20944/preprints202308.1547.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Main Protease Inhibitors; SARS-CoV-2; COVID-19; mutations; vaccines; therapeutics; drug repurposing; management strategies
Online: 22 August 2023 (09:31:05 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1427.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
pulmonary tuberculosis, Mycobacterium tuberculosis, alveolar macrophages, drug tolerance, persistence, dormancy, biomarkers, non-acid-fastness, Rv2623
Online: 21 August 2023 (12:11:01 CEST)
ARTICLE
|
doi:10.20944/preprints202307.1647.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
non-steroidal anti-inflammatory drug; stroke; acute coronary syndrome; myocardial infarction; mortality; readmission; Arabian Gulf
Online: 25 July 2023 (08:26:22 CEST)
ARTICLE
|
doi:10.20944/preprints202307.1492.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
HIV; antiretroviral drug; combination antiretroviral therapy; mitochondrial dysfunction; human microglia; iron; neural cell; metabolic reprogramming
Online: 21 July 2023 (09:50:45 CEST)
ARTICLE
|
doi:10.20944/preprints202307.1256.v1
Subject:
Medicine And Pharmacology,
Psychiatry And Mental Health
Keywords:
Opiates, Opium smoking, Neck pain, Neck disability, Forward head posture, Hyperkyphosis, Drug use disorder, Iran
Online: 18 July 2023 (15:56:47 CEST)
REVIEW
|
doi:10.20944/preprints202306.1921.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Antibiotic resistance; Drug designing; Bacterial mutation; Bacterial evolution; Horizontal gene transfer; Public and agricultural health
Online: 27 June 2023 (13:55:21 CEST)
ARTICLE
|
doi:10.20944/preprints202306.1494.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
microgravity; chemotherapy; paclitaxel; hydroxyurea; morphometry; drug response; immune dysfunction; space medicine; terrestrial medicine; fluorescence microscopy
Online: 21 June 2023 (07:34:49 CEST)
REVIEW
|
doi:10.20944/preprints202306.1176.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
lung cancer; organoid; drug screening; high throughput; translational; pre-clinical; clinical; tumor microenvironment; personalized medicine
Online: 16 June 2023 (08:42:28 CEST)
ARTICLE
|
doi:10.20944/preprints202306.0723.v1
Subject:
Medicine And Pharmacology,
Complementary And Alternative Medicine
Keywords:
Synergistic effect; Antibiotic resistance; Medicinal Plants; Penicillin G; Sutherlandia Frutescens; Microbial sensitivity tests; Drug combinations
Online: 9 June 2023 (13:09:26 CEST)
ARTICLE
|
doi:10.20944/preprints202304.0914.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Metformin; Quorum sensing; Quorum quenching; Pseudomonas aeruginosa; Virulence; Drug repurposing; Anti-virulence therapy; Biofilm inhibition
Online: 25 April 2023 (09:54:20 CEST)
COMMUNICATION
|
doi:10.20944/preprints202212.0060.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
exosomes; extrusion; proteolipid nanoparticles; drug delivery; nanomedicine; doxorubicin; ex-truded nanoparticles; hydroxychloroquine; endolysosomal escape; lysosomotropic
Online: 5 December 2022 (06:04:21 CET)
REVIEW
|
doi:10.20944/preprints202210.0450.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Tumor microenvironment; stromal cells; immune cells; ECM; cancer hallmarks; hypoxia; exosomes; drug resistance; targeted therapy
Online: 28 October 2022 (09:57:34 CEST)
ARTICLE
|
doi:10.20944/preprints202210.0223.v3
Subject:
Biology And Life Sciences,
Virology
Keywords:
Drug discovery; Systems biology; SARS-CoV-2; Dengue; Influenza A; RSV; cell viability analysis; antivirals; in vitro validation; in vivo validation
Online: 22 March 2024 (16:46:59 CET)
ARTICLE
|
doi:10.20944/preprints202205.0256.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Extracellular matrices; Macromolecular crowding; human iPSC derived astrocytes; human iPSC derived dopaminergic neurons; drug testing
Online: 19 May 2022 (08:50:28 CEST)
ARTICLE
|
doi:10.20944/preprints202205.0224.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
age-related macular degeneration; light-induced photoreceptor degeneration; anti-inflammatory drug; toll-like receptor 4
Online: 17 May 2022 (08:03:11 CEST)
ARTICLE
|
doi:10.20944/preprints202203.0117.v3
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
active pharmaceutical ingredient; compounded drug; compounding; extemporaneous formulation; manufactured material; medication; monograph; pediatric; reference standards
Online: 5 April 2022 (10:17:10 CEST)
ARTICLE
|
doi:10.20944/preprints202112.0122.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
hepatitis B virus; besifovir dipivoxil maleate (BSV); nucleos(t)ide analog; drug resistance; reverse transcription
Online: 8 December 2021 (12:06:52 CET)
REVIEW
|
doi:10.20944/preprints202111.0317.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Non-Hodgkin lymphoma; Epigenetics; DNA methylation; HAT; HDAC; EZH2; bromodomain inhibitors; Drug combination; clinical testing
Online: 17 November 2021 (23:45:00 CET)
ARTICLE
|
doi:10.20944/preprints202111.0125.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
artificial intelligence; de novo design; fragment-based drug discovery; HIV-1 inhibitors; pseudo natural products
Online: 8 November 2021 (09:23:49 CET)
REVIEW
|
doi:10.20944/preprints202109.0491.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Tuberculosis; Mycobacterium; Diagnostics; Drug Discovery; Antibiotics; Antimicrobial Re-sistance; Microfluidics; Single-Cell Analysis; Bioengineered Models
Online: 29 September 2021 (11:34:04 CEST)
REVIEW
|
doi:10.20944/preprints202109.0432.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Non-genetic heterogeneity; multistability; drug-tolerant persisters; phenotypic plasticity; biological noise; epithelial-mesenchymal plasticity; PAGE4
Online: 24 September 2021 (12:44:34 CEST)
ARTICLE
|
doi:10.20944/preprints202108.0359.v2
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
1, 2, 4-Triazine; Lanosterol 14a-demethylase (CYP51); Drug Resistance; Molecular Docking; Molecular Dynamic Simulation.
Online: 17 August 2021 (12:27:02 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
gas chromatography mass spectrometry; metabolomics; acute lymphoblastic leukemia; confocal microscopy; high-throughput drug screens; VAST
Online: 7 June 2021 (08:01:21 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0492.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Drug resistance; nsp12; protein design; fitness; RNA-dependent RNA polymerase; resistance mutations; SARS-CoV-2.
Online: 20 May 2021 (13:18:14 CEST)
REVIEW
|
doi:10.20944/preprints202105.0311.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Angiotensin converting enzyme 2; breast feeding; drug therapy; pregnancy; severe acute respiratory syndrome coronavirus 2
Online: 13 May 2021 (15:26:34 CEST)
ARTICLE
|
doi:10.20944/preprints202101.0490.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
CD44; Cancer Stem Cells; Tumorigenesis; Drug Resistance; Immune Markers; Epithelial to Mesenchymal Transition; Therapeutic Targeting
Online: 25 January 2021 (12:23:49 CET)