ARTICLE
|
doi:10.20944/preprints202111.0125.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
artificial intelligence; de novo design; fragment-based drug discovery; HIV-1 inhibitors; pseudo natural products
Online: 8 November 2021 (09:23:49 CET)
REVIEW
|
doi:10.20944/preprints202109.0491.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Tuberculosis; Mycobacterium; Diagnostics; Drug Discovery; Antibiotics; Antimicrobial Re-sistance; Microfluidics; Single-Cell Analysis; Bioengineered Models
Online: 29 September 2021 (11:34:04 CEST)
REVIEW
|
doi:10.20944/preprints202109.0432.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Non-genetic heterogeneity; multistability; drug-tolerant persisters; phenotypic plasticity; biological noise; epithelial-mesenchymal plasticity; PAGE4
Online: 24 September 2021 (12:44:34 CEST)
ARTICLE
|
doi:10.20944/preprints202108.0359.v2
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
1, 2, 4-Triazine; Lanosterol 14a-demethylase (CYP51); Drug Resistance; Molecular Docking; Molecular Dynamic Simulation.
Online: 17 August 2021 (12:27:02 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
gas chromatography mass spectrometry; metabolomics; acute lymphoblastic leukemia; confocal microscopy; high-throughput drug screens; VAST
Online: 7 June 2021 (08:01:21 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0492.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Drug resistance; nsp12; protein design; fitness; RNA-dependent RNA polymerase; resistance mutations; SARS-CoV-2.
Online: 20 May 2021 (13:18:14 CEST)
REVIEW
|
doi:10.20944/preprints202105.0311.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Angiotensin converting enzyme 2; breast feeding; drug therapy; pregnancy; severe acute respiratory syndrome coronavirus 2
Online: 13 May 2021 (15:26:34 CEST)
ARTICLE
|
doi:10.20944/preprints202101.0490.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
CD44; Cancer Stem Cells; Tumorigenesis; Drug Resistance; Immune Markers; Epithelial to Mesenchymal Transition; Therapeutic Targeting
Online: 25 January 2021 (12:23:49 CET)
COMMUNICATION
|
doi:10.20944/preprints202012.0823.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
neuroscience; rheumatology; osteoarthritis; pain; peripheral nerve; biological drug; growth factor; peptide; monoclonal antibody; ion channel
Online: 31 December 2020 (15:41:05 CET)
REVIEW
|
doi:10.20944/preprints202008.0320.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
Data Science; Machine Learning; Deep Learning; Genomics; COVID-19; Drug Discovery; Image Analysis; Interactomics; Epidemiology
Online: 14 August 2020 (11:01:56 CEST)
ARTICLE
|
doi:10.20944/preprints202001.0219.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
protruding features; spherical virus; point arrays; surface modifications; VLP; drug delivery; icosahedral; nanomedicine; ligand binding
Online: 20 January 2020 (06:59:09 CET)
ARTICLE
|
doi:10.20944/preprints201908.0131.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
pharmacogenomics; immune checkpoint blockade; immunotherapy; drug response prediction; algorithm; mathematical model; precision medicine; personalized medicine
Online: 11 August 2019 (14:51:14 CEST)
ARTICLE
|
doi:10.20944/preprints201901.0046.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Keywords: methotrexate, cubic phase, magnetocubosomes, monoolein, liquid crystalline phase, drug delivery system, alternating magnetic field
Online: 4 January 2019 (14:32:38 CET)
REVIEW
|
doi:10.20944/preprints201709.0166.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Alzheimer's disease; drug targeting; nanoemulsion; neuroinflammation; neurotrauma; oxidative stress; scavenger receptors; SR-BI; transcranial sonoporation
Online: 30 September 2017 (05:21:37 CEST)
ARTICLE
|
doi:10.20944/preprints202402.1376.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
keyword Glucose uptake, Yeast cell line, Abelmoschus esculentus L., Extract fractions, Type 2 diabetes, drug candidate.
Online: 23 February 2024 (11:21:02 CET)
REVIEW
|
doi:10.20944/preprints202402.1049.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
malignant pleural mesothelioma; immune checkpoint inhibitor; orphan drug; good clinical practice; Pharmaceuticals and Medical Devices Agency
Online: 20 February 2024 (04:03:22 CET)
REVIEW
|
doi:10.20944/preprints202312.0726.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
aerosol; nebulization; inhalation; airflow dynamics; particle deposition; particle-lung interactions; smart inhalers; AI in drug delivery
Online: 11 December 2023 (16:06:30 CET)
REVIEW
|
doi:10.20944/preprints202311.0094.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Casein Kinase II; Musculoskeletal; Osteoarthritis; Osteoporosis; CX-4945; CIBG-300; Cell Signaling; Drug Development; Targeted therapy
Online: 1 November 2023 (13:18:42 CET)
ARTICLE
|
doi:10.20944/preprints202310.0781.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Ivermectin; ribavirin; acyclovir; ferruginol; direct-acting antivirals; host-targeting antivirals; drug combinations; CHIKV; ZIKV; HHV-2.
Online: 12 October 2023 (09:15:29 CEST)
ARTICLE
|
doi:10.20944/preprints202310.0708.v1
Subject:
Public Health And Healthcare,
Other
Keywords:
Candida glabrata; fungal drug resistance; reverse transcriptase polymerase chain reaction; fluconazole; molecular docking simulation; multivariate analysis
Online: 11 October 2023 (12:24:15 CEST)
ARTICLE
|
doi:10.20944/preprints202309.2164.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Ewing sarcoma; drug synergy; Kinesin Family Member 11; Aurora Kinase A; SB-743921; and VIC-1911
Online: 30 September 2023 (08:26:49 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0274.v1
Subject:
Engineering,
Bioengineering
Keywords:
Fluorescence Imaging; Multispectral and hyperspectral imaging; Solvatochromic shift; Tunable Lasers; Spectroscopy; DMSO Sensing; Drug uptake monitoring
Online: 6 September 2023 (14:57:35 CEST)
REVIEW
|
doi:10.20944/preprints202309.0207.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Neglected tropic diseases; Parasites; Chagas disease; Leishmaniasis; Life cycle; Drug target; Biochemical mechanisms; Pharmacological therapeutics; Peptides
Online: 6 September 2023 (14:52:33 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1963.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
Core-shell nanogels; nonlinear PEG; anisole; biocompatible; thermo-responsive; curcumin stability, high loading capacity; drug delivery
Online: 30 August 2023 (04:08:45 CEST)
REVIEW
|
doi:10.20944/preprints202306.0066.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Systems Biology; Multiomics; Cryptosporidium; Giardia; Entamoeba; Anti-Microbial Resistance; Multi Drug Resistance; Probiotic; Prebiotics, Synbiotics; Postbiotics
Online: 1 June 2023 (08:29:21 CEST)
REVIEW
|
doi:10.20944/preprints202305.1646.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
graphene-based nanomaterials; graphene-based drug delivery systems; lysosomes; cancer; endosomal/lysosomal escape; lysosomal cell death
Online: 23 May 2023 (10:52:24 CEST)
REVIEW
|
doi:10.20944/preprints202305.0289.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
cancer therapy; nanomedicine; drug delivery; pH-responsiveness; EPR; intratumoral delivery; intracellular delivery; nanoparticles; metal-organic frameworks
Online: 5 May 2023 (03:45:54 CEST)
ARTICLE
|
doi:10.20944/preprints202209.0188.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
MTBC; virtual screening; topological indices; linear discriminant analysis; pharmacological activity distribution diagrams; antimicrobial drugs; drug design
Online: 14 September 2022 (03:32:55 CEST)
ARTICLE
|
doi:10.20944/preprints202205.0392.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
atrial-fibrillation; multi-target; drug promiscuity; druggable binding site; flecainide; Nav1.5; Kv1.5; binding site comparison; polypharmacology
Online: 30 May 2022 (10:10:41 CEST)
HYPOTHESIS
|
doi:10.20944/preprints202202.0032.v1
Subject:
Engineering,
Bioengineering
Keywords:
Organ-on-a-Chip (OoC); Micro-physiological systems (MPS); survey; usability; limitations; disease models; drug testing
Online: 2 February 2022 (12:20:19 CET)
ARTICLE
|
doi:10.20944/preprints202111.0395.v1
Subject:
Chemistry And Materials Science,
Physical Chemistry
Keywords:
Tamarind Gum; Hydrogels; Semi-IPNs; Green synthesis; Silver Nanoparticles; Drug Delivery; Chemotherapeutics; HCT116 Cell; Anti-microbial
Online: 22 November 2021 (13:46:47 CET)
REVIEW
|
doi:10.20944/preprints202101.0325.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
pediatric cancer; nanoparticles; drug delivery system; liposome; leukemia; lymphoma; osteosarcoma; Ewing sarcoma; glioma; blood-brain barrier
Online: 18 January 2021 (11:58:32 CET)
ARTICLE
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
COVID-19; SARS-CoV-2; in silico drug discovery; gene expression profile; tensor decomposition; feature extraction
Online: 8 December 2020 (10:17:05 CET)
REVIEW
|
doi:10.20944/preprints202009.0405.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
horizontal gene transfer; bacterial conjugation; phenotypic conversion; drug-resistance dissemination; bacterial biofilms; mobile plasmids; F plasmid
Online: 17 September 2020 (12:00:29 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Covid-19; proteins; normal-modes; protein-drug interactions; chloroquine; ivermectin; remdesivir; sofosbuvir; boceprevir; α-difluoromethylornithine (DMFO)
Online: 11 August 2020 (04:09:43 CEST)
ARTICLE
|
doi:10.3390/sci2020045
Subject:
Medicine And Pharmacology,
Tropical Medicine
Keywords:
adverse drug reactions; antimalarial; Ghana; herbal remedies; malaria; questionnaire; street sale; orthodox; unnatural medicines; patient preference
Online: 12 June 2020 (00:00:00 CEST)
COMMUNICATION
|
doi:10.20944/preprints202002.0421.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
De novo transcriptome assembly; brushtail possums; liver; brain cerebral cortex; drug and xenobiotic metabolism; chemical toxicants
Online: 28 February 2020 (11:49:29 CET)
ARTICLE
|
doi:10.20944/preprints202002.0009.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
target identification; drug affinity responsive target stability (DARTS); mass spectrometry imaging (MSI); voacangine; curcumin; natural products
Online: 3 February 2020 (04:36:54 CET)
ARTICLE
|
doi:10.20944/preprints201912.0049.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
natural product; drug discovery; protoflavonoid; continuous-flow chemistry; oxime; antitumor; antiviral; epstein-barr virus; lytic cycle
Online: 4 December 2019 (11:40:33 CET)
REVIEW
|
doi:10.20944/preprints201910.0296.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
nasal delivery; glioblastoma multiforme; drug delivery; nanoparticles; nose-to-brain delivery; pre-clinical studies; clinical evaluation
Online: 27 October 2019 (09:36:27 CET)
ARTICLE
|
doi:10.20944/preprints201809.0292.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
monoglyceride colloidal liquid crystals; release profile; mathematical models; drug delivery systems; release kinetic; square root laws
Online: 17 September 2018 (09:33:52 CEST)
REVIEW
|
doi:10.20944/preprints201807.0241.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
biomaterial; bone regeneration; drug release; hydrogel; lignin; multivariate data processing; osteogenesis; scaffolds; stem cells; tissue engineering
Online: 13 July 2018 (15:07:37 CEST)
ARTICLE
|
doi:10.20944/preprints202408.1451.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
depression; adolescent girls; National Survey on Drug Use and Health; family structure, parenting style, negative school experience
Online: 20 August 2024 (13:44:36 CEST)
ARTICLE
|
doi:10.20944/preprints202407.1330.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
modular nanotransporters; targeted drug delivery; photosensitizers; anticancer drugs; photodynamic effect; epidermal growth factor receptors; binding; importins; Keap1
Online: 16 July 2024 (17:05:37 CEST)
REVIEW
|
doi:10.20944/preprints202407.0821.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
Nanogels; nanoparticle synthesis; hydrogels and microgels; batch chemistry; flow chemistry; microfluidics; nanomedicine; theranostics; cross-linking; drug delivery
Online: 10 July 2024 (05:08:20 CEST)
REVIEW
|
doi:10.20944/preprints202406.0054.v1
Subject:
Medicine And Pharmacology,
Dermatology
Keywords:
melanoma; cancer vaccine; mRNA vaccine; renin-angiotensin system; drug repurposing; immunotherapy; embryonic stem cells; cancer stem cells
Online: 3 June 2024 (09:54:04 CEST)
ARTICLE
|
doi:10.20944/preprints202405.1908.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Breast cancer; Target Identification; Protein-Protein Interaction; Network Pharmacology; Drug Discovery; KEEG; Enrichment analysis; Text Mining; Cytoscape
Online: 29 May 2024 (08:33:40 CEST)
ARTICLE
|
doi:10.20944/preprints202403.0918.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
Raman technology; recovery and resource utilization technology; process control; biogenic carbonate waste; chitin; calcium acetate drug; carotenoids.
Online: 15 March 2024 (12:01:12 CET)
ARTICLE
|
doi:10.20944/preprints202312.1002.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
intranasal spray; drug delivery; respiratory transport modeling; respiratory diseases; upper airway physiology; targeted nasal therapy; gentlemistTM technology
Online: 13 December 2023 (13:05:13 CET)
REVIEW
|
doi:10.20944/preprints202306.0932.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
gastric cancer; HER2; immunotherapy; PD-1/PD-L1; antibody-drug conjugate; chemotherapy; trastuzumab; novel therapies; clinical trials
Online: 13 June 2023 (11:15:24 CEST)
REVIEW
|
doi:10.20944/preprints202212.0048.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
poly(hexamethylene biguanide); polyhexamethylene biguanide; polyhexanide; PHMB; membrane; controlled drug release; wound dressing; antimicrobial; cytotoxicity; wound healing
Online: 2 December 2022 (10:31:38 CET)
ARTICLE
|
doi:10.20944/preprints202212.0013.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
poly(lactic-co-glycolic acid); silica; nanoparticles; enzymes; amino acid depletion; cancer; drug delivery; double emulsion; biocompatible
Online: 1 December 2022 (07:56:18 CET)
ARTICLE
|
doi:10.20944/preprints202211.0144.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Urinary tract infection; Ghana; Antimicrobial resistance (AMR); Multi-drug resistance (MDR); MDS Lancet Laboratories; AWaRE classification; Uropathogens
Online: 8 November 2022 (03:25:41 CET)
REVIEW
|
doi:10.20944/preprints202209.0201.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
ligand-based pharmacophores; structure-based pharmacophores; virtual screening; drug design; machine learning; molecular dynamics; de novo design
Online: 14 September 2022 (09:10:58 CEST)
REVIEW
|
doi:10.20944/preprints202207.0141.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
review; real -world evidence; real -world data; randomized controlled trials; registry; digital health technology; early drug approval
Online: 8 July 2022 (11:09:58 CEST)
ARTICLE
|
doi:10.20944/preprints202109.0052.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
RNAi; drug delivery; siRNA delivery; DsiRNA delivery; RNAi delivery; Chol-DsiRNA polymer micelles; Chol-siRNA polymer micelles
Online: 3 September 2021 (08:56:48 CEST)
REVIEW
|
doi:10.20944/preprints202108.0112.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Epitranscriptomics, Immune checkpoint blockage (ICB) therapy, anti-PD-1/PD-L1 drug resistance, Personalized medicine, CISH, microRNAs
Online: 4 August 2021 (13:02:22 CEST)
ARTICLE
|
doi:10.20944/preprints202106.0618.v1
Subject:
Medicine And Pharmacology,
Other
Keywords:
Chemical Intolerance, Drug Intolerance, Food Intolerance, QEESI, BREESI, Multiple Chemical Sensitivity, Toxicant-induced Loss of Tolerance, Prevalence
Online: 25 June 2021 (11:49:32 CEST)
ARTICLE
|
doi:10.20944/preprints202106.0169.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
melanoma initiating cells; CD133; drug resistance; apoptosis; caspase activation; CRISPR-Cas9 knockout; AKT; BAD; BCL-2 family
Online: 7 June 2021 (12:11:10 CEST)
REVIEW
|
doi:10.20944/preprints202102.0619.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Nanotechnology 1; Nanomedicine 2; organic and inorganic nanoparticles 3; drug delivery 4; antitumour therapy5; tissue engineering 6.
Online: 26 February 2021 (13:31:45 CET)
ARTICLE
|
doi:10.20944/preprints202102.0505.v1
Subject:
Chemistry And Materials Science,
Physical Chemistry
Keywords:
adhesion; self-assembly; drug delivery; curved surface; template-assisted self-assembly; nanotechnology; single-molecule system; polymer nanocomposite.
Online: 23 February 2021 (09:35:14 CET)
REVIEW
|
doi:10.20944/preprints202012.0029.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
drug delivery; immune response; inflammation; critical solution temperature; scaffolds; smart polymers; tissue engineering; thermo-responsive; wound healing.
Online: 1 December 2020 (13:55:35 CET)
REVIEW
|
doi:10.20944/preprints202004.0122.v2
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
melatonin; coronavirus; pandemic; SARS-CoV-2; bat; lung; apoptosis; programmed cell death; mortality; morbidity; COVID-19; drug
Online: 9 April 2020 (09:24:47 CEST)
ARTICLE
|
doi:10.20944/preprints202003.0440.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
COVID-19; SARS-CoV-2; 2019-nCoV; novel corona virus; drug repurposing; chloroquine; high-risk group; asymptomatic
Online: 30 March 2020 (07:24:16 CEST)
ARTICLE
|
doi:10.20944/preprints201905.0370.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Targeted drug delivery, VX2 tumor, breast cancer, cryoablation, cryo-assisted injection, cryo-assisted resection, blue dye, epirubicin.
Online: 30 May 2019 (13:44:41 CEST)
ARTICLE
|
doi:10.20944/preprints201812.0018.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
colorectal cancer; differentially expressed genes; biomarkers; protein-protein interaction; reporter biomolecules; candidate drugs; systems biology; drug repositioning
Online: 29 December 2018 (07:05:05 CET)
ARTICLE
|
doi:10.20944/preprints201809.0544.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
Bodybuilding; Drug Free; Competing; Peaking; Carbohydrate Loading; Water Loading; Sodium Loading; Fat Loading: Vitamin C; Fibre Restriction
Online: 27 September 2018 (12:58:34 CEST)
ARTICLE
|
doi:10.20944/preprints201706.0132.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
arylamine N-acetyltransferases; cancer; tuberculosis; drug discovery; traditional Chinese medicine; virtual screening; molecular dynamics simulation; MM-PBSA
Online: 30 June 2017 (11:36:22 CEST)
ARTICLE
|
doi:10.20944/preprints201704.0023.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
gelatin-oleic conjugate; self-assembled biodegradable nanoparticles; biomimetic shear stress; cell dynamic environment; cellular drug delivery; paclitaxel
Online: 4 April 2017 (10:59:02 CEST)
ARTICLE
|
doi:10.20944/preprints202403.1686.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
lung adenocarcinoma; drug-tolerant persister (DTP) cells; intrinsic resistance; tyrosine kinase inhibitors (TKIs); erlotinib; osimertinib; senescent cells; CD74
Online: 28 March 2024 (12:16:57 CET)
ARTICLE
|
doi:10.20944/preprints202401.1163.v1
Subject:
Medicine And Pharmacology,
Psychiatry And Mental Health
Keywords:
opioids; opium smoking; substance use disorder; behavioral addiction; drug use disorder; sway back posture; musculoskeletal disorders; Nordic; Iran
Online: 16 January 2024 (09:42:41 CET)
REVIEW
|
doi:10.20944/preprints202311.0017.v1
Subject:
Public Health And Healthcare,
Primary Health Care
Keywords:
nanomedicine; CNS cancer; therapeutics; blood-brain barrier; personalized medicine; nanoparticles; COVID-19; drug delivery; regulatory landscape; precision oncology
Online: 1 November 2023 (08:31:47 CET)
COMMUNICATION
|
doi:10.20944/preprints202309.1794.v1
Subject:
Medicine And Pharmacology,
Complementary And Alternative Medicine
Keywords:
SARS; Covid-19; HIV; MRSA; Biophotonics; Energy Dynamics; Electromagnetic therapy; irradiation; immunomodulation; infectious illnesses; drug resistance; therapeutic efficacy
Online: 27 September 2023 (04:45:42 CEST)
ARTICLE
|
doi:10.20944/preprints202307.1267.v1
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
high-intensity broadband optical radiation; pathogens with multiple drug resistance; pulsed xenon lamp; phototherapy devise; wound healing; dose
Online: 19 July 2023 (09:34:21 CEST)
ARTICLE
|
doi:10.20944/preprints202304.0082.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
COVID-19; drug repurposing; methotrexate; EXSCALATE; virtual screening; molecular docking; antiviral activity; SARS-CoV-2; viral entry; nsp13
Online: 6 April 2023 (09:21:51 CEST)
ARTICLE
|
doi:10.20944/preprints202209.0232.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
Drug use review; Outpatients; Ghana; SORT IT; Quality indicators; Electronic Medical Records; Operational research; Rational use of medicines
Online: 15 September 2022 (13:39:06 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0169.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Split-intein circular ligation of peptides and proteins (SICLOPPS); cyclic peptide libraries; protein–protein interactions; drug; gateway cloning
Online: 6 April 2021 (10:19:49 CEST)
ARTICLE
|
doi:10.20944/preprints202008.0316.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
nanoparticles; FA-DABA-SMA; drug delivery systems; folic acid receptor alpha; intracellular disruptions; invasion and migration; breast cancer
Online: 14 August 2020 (09:49:17 CEST)
ARTICLE
|
doi:10.20944/preprints201908.0177.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
chronic myeloid leukemia; tyrosine kinase inhibitor; adverse drug event; quality of life; second-generation tyrosine kinase inhibitor; nilotinib
Online: 16 August 2019 (08:09:07 CEST)
ARTICLE
|
doi:10.20944/preprints201905.0109.v2
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
child; diarrhea; water sanitation and hygiene; rehydration solution; zinc; case management; antibacterial agents; drug utilization; community participation; India
Online: 14 May 2019 (11:46:53 CEST)
REVIEW
|
doi:10.20944/preprints201812.0273.v3
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
mutations; disease-causing mutations; polymorphism; folding free energy change; binding free energy change; drug discovery; in silico screening
Online: 28 January 2019 (11:39:23 CET)
REVIEW
|
doi:10.20944/preprints201810.0577.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
myeloma; daratumumab; elotuzumab; isatuximab; CD38; JNJ- 63723283; denosumab; checkpoint inhibitors; BCMA; bispecific T-cell engager; antibody-drug conjugates
Online: 24 October 2018 (12:11:23 CEST)
ARTICLE
|
doi:10.20944/preprints201809.0513.v1
Subject:
Medicine And Pharmacology,
Tropical Medicine
Keywords:
Malawi, HIV, tuberculosis, anti-retroviral therapy, surveillance, patient monitoring, epidemic trends, drug supply, unique patient identifiers, data analysis
Online: 27 September 2018 (15:29:43 CEST)
REVIEW
|
doi:10.20944/preprints201807.0116.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
chemical space; chemoinformatics; data mining; databases; DNMT inhibitors; drug discovery; epi-informatics; molecular modeling; similarity searching; virtual screening
Online: 6 July 2018 (10:04:44 CEST)
REVIEW
|
doi:10.20944/preprints201802.0190.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Alzheimer’s disease; biomimetic nanocarriers; blood-brain barrier; dementia; drug targeting; lipid cubic phases; nanoemulsion; SR-BI; scavenger receptors
Online: 28 February 2018 (07:49:13 CET)
REVIEW
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
metabolic functionalization of alkyl moieties in drug molecules; structure influence on metabolic functionalization of alkyl moieties; mechanism of alkyl free radical hydroxy functionalization; pharmacologic activity of hydroxy and carboxy functionalized alkyl moieties in drug molecules; primary and auxiliary pharmacophores; auxophores
Online: 11 March 2020 (03:20:58 CET)
HYPOTHESIS
|
doi:10.20944/preprints202407.1192.v1
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
Homeostasis; Epigenetics; Epimutations; Hormesis; Toxicogenomics; Quantum biology; Superposition reference image, Ultra high dilutions. Quantum drug action.
Online: 16 July 2024 (00:14:47 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0762.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
high-throughput screening; metabolic stability; ambient mass spectrometry; LA-REIMS; biomimetic metalloporphyrin; lead profiling; in vitro models; drug metabolism
Online: 12 June 2024 (14:15:32 CEST)
ARTICLE
|
doi:10.20944/preprints202405.0084.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
natural extracts; chitosan; liposomes; encapsulation; drug release; coronavirus HCoV-0C43; antiviral activity; natural inhibitors of viral replication; cytotoxicity; phototoxicity
Online: 2 May 2024 (12:03:47 CEST)
REVIEW
|
doi:10.20944/preprints202402.1435.v1
Subject:
Medicine And Pharmacology,
Internal Medicine
Keywords:
secondary movement disorders; dystonia; chorea; athetosis; myoclonus; tics; tremor; drug-induced movement disorders; post-infectious movement disorders; metabolic disorders
Online: 26 February 2024 (11:45:00 CET)
ARTICLE
|
doi:10.20944/preprints202305.0650.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
3D printing; hybrid scaffold; poly(caprolactone); chitosan; vancomycin; mesenchymal stem cells; tissue engineering; drug-delivery systems (DDSs); M osteomyelitis
Online: 9 May 2023 (12:05:37 CEST)
ARTICLE
|
doi:10.20944/preprints202304.1195.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
COVID-19 pandemic; antimicrobial resistance; infectious diseases consultation; multi-drug resistant bacteria; infection prevention and control group; antibiotic stewardship
Online: 29 April 2023 (03:23:00 CEST)
ARTICLE
|
doi:10.20944/preprints202209.0417.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
Recreational substance abuse; drug abuse; marijuana; amphetamine; acute ischemic stroke; risk factors; young adult; NIS; Stroke; Sudden Cardiac Death
Online: 27 September 2022 (09:41:00 CEST)
REVIEW
|
doi:10.20944/preprints202108.0447.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Interferons; IFNα; IFNß; IFNγ; antiviral; antiproliferative; immunomodulator; PEGylation; formulation; encapsulate IFNs; drug delivery system; liposomes; polymeric micelles; microparticles; nanoparticles
Online: 23 August 2021 (13:51:44 CEST)
REVIEW
|
doi:10.20944/preprints202101.0625.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Alzheimer’s disease; dementia, beta-amyloid; germ theory; drug development; clinical trials; herpes; spirochetes; Chlamydia pneumoniae; Porphyromonas gingivalis; toxoplasma; mycobacteria
Online: 29 January 2021 (13:57:18 CET)
REVIEW
|
doi:10.20944/preprints202012.0044.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Integrins; Tumor Microenvironment; Drug Resistance; Migration; Metastasis; Solid Tumors; The Cancer Genome Atlas; Gene Expression; Computational Biology; Therapeutic Targeting
Online: 1 December 2020 (18:26:11 CET)
ARTICLE
|
doi:10.20944/preprints202011.0474.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
Breast cancer, genome-scale metabolic models, constraint-based analysis, divergence analysis, gene expression, metabolism, drug targets, personalized metabolic networks.
Online: 18 November 2020 (12:29:02 CET)
ARTICLE
|
doi:10.20944/preprints202011.0054.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
3D printing; semi-solid extrusion 3D printing; additive manufacturing; extemporaneous manufacturing; drug delivery; personalized dosage forms; veterinary medicine; prednisolone
Online: 2 November 2020 (14:59:30 CET)
REVIEW
|
doi:10.20944/preprints202010.0179.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Non Michaelis-Menten Kinetics; High-throughput screening; allostery; cooperativity; processive kinetics; distributive kinetics; single-molecule; auto-catalytic; drug discovery
Online: 8 October 2020 (13:34:16 CEST)
ARTICLE
|
doi:10.20944/preprints202005.0199.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
SARS-CoV-2; COVID-19; CADD; virtual screening; approved drugs; drug repurposing; essential targets; molecular docking; molecular dynamics simulations
Online: 11 May 2020 (13:14:18 CEST)