REVIEW
|
doi:10.20944/preprints202309.1793.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
neurodegenerative disorders; blood-brain barrier; non-invasive delivery; device-related delivery; Alzheimer’s; Parkinson’s; ALS; Down Syndrome
Online: 27 September 2023 (04:19:06 CEST)
ARTICLE
|
doi:10.20944/preprints202201.0285.v1
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
Health Related Quality of Life, EQ-5D-Y-3L, EQ-5D-Y-5L, Youth, children, orthopaedic
Online: 20 January 2022 (07:23:51 CET)
ARTICLE
|
doi:10.20944/preprints202002.0186.v1
Subject:
Medicine And Pharmacology,
Anesthesiology And Pain Medicine
Keywords:
breakthrough cancer pain; cancer-associated pain; cancer; health-related quality of life; sleep disorders; transmucosal fentanyl
Online: 14 February 2020 (03:36:53 CET)
REVIEW
|
doi:10.20944/preprints201806.0205.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Aryl hydrocarbon receptor; Chloracne; Dioxin; Nuclear factor-erythroid 2-related factor-2; heme oxygenase-1; Yusho
Online: 13 June 2018 (10:29:35 CEST)
REVIEW
|
doi:10.20944/preprints201810.0369.v1
Subject:
Medicine And Pharmacology,
Dietetics And Nutrition
Keywords:
Age-Related Macular Degeneration, Gut-retina axis, Gut microbiota, Dietary habits, Micronutrients, Fish oil, omega-3 Polyunsaturated fatty acids, Personalised medicine
Online: 16 October 2018 (17:39:27 CEST)
ARTICLE
Subject:
Computer Science And Mathematics,
Mathematical And Computational Biology
Keywords:
c-src-tyrosine kinase; QSAR; molecular descriptors; virtual screening; drug discovery; cancer; molecular docking
Online: 25 October 2019 (11:21:43 CEST)
ARTICLE
|
doi:10.20944/preprints202002.0009.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
target identification; drug affinity responsive target stability (DARTS); mass spectrometry imaging (MSI); voacangine; curcumin; natural products
Online: 3 February 2020 (04:36:54 CET)
ARTICLE
|
doi:10.20944/preprints202407.0129.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
Atypical antipsychotics (AAPs), secondary drug effects, schizophrenia, liver, mitochondria, oxidative stress (OS), MAPK.
Online: 2 July 2024 (13:23:11 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0533.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
therapeutic drug monitoring (TDM); extracorporeal therapies; CKRT; hemoadsorption; cytosorb; antimicrobials; clearance; mass removal
Online: 7 August 2023 (10:46:18 CEST)
ARTICLE
|
doi:10.20944/preprints202306.0259.v1
Subject:
Public Health And Healthcare,
Public, Environmental And Occupational Health
Keywords:
SARS-CoV-2 infection; COVID-19 disease; women´s health; menstrual-related disturbances; formerly menstruating women; secondary amenorrhea; perimenopause; heavy menstrual bleeding
Online: 5 June 2023 (07:58:02 CEST)
ARTICLE
|
doi:10.20944/preprints202201.0082.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
breast cancer; cancer stem cell; therapy resistance; cationic amphiphilic drug; lysosome-dependent cell death
Online: 6 January 2022 (11:51:28 CET)
ARTICLE
|
doi:10.20944/preprints202108.0527.v1
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
PSPS; FBSS; chronic pain; health-related quality of life; mixture models analysis; personalized pain management; chronic pain after spinal surgery
Online: 27 August 2021 (15:23:27 CEST)
REVIEW
|
doi:10.20944/preprints202110.0450.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
Fibrosis; Integrin; TGFβ; Therapeutic target; Drug; Inhibitor; Monoclonal antibody; α8β1; α11β1; Hepatic stellate cell
Online: 29 October 2021 (10:16:13 CEST)
ARTICLE
|
doi:10.20944/preprints202310.0781.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Ivermectin; ribavirin; acyclovir; ferruginol; direct-acting antivirals; host-targeting antivirals; drug combinations; CHIKV; ZIKV; HHV-2.
Online: 12 October 2023 (09:15:29 CEST)
ARTICLE
|
doi:10.20944/preprints202307.1256.v1
Subject:
Medicine And Pharmacology,
Psychiatry And Mental Health
Keywords:
Opiates, Opium smoking, Neck pain, Neck disability, Forward head posture, Hyperkyphosis, Drug use disorder, Iran
Online: 18 July 2023 (15:56:47 CEST)
REVIEW
|
doi:10.20944/preprints201709.0166.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Alzheimer's disease; drug targeting; nanoemulsion; neuroinflammation; neurotrauma; oxidative stress; scavenger receptors; SR-BI; transcranial sonoporation
Online: 30 September 2017 (05:21:37 CEST)
ARTICLE
|
doi:10.20944/preprints202310.0708.v1
Subject:
Public Health And Healthcare,
Other
Keywords:
Candida glabrata; fungal drug resistance; reverse transcriptase polymerase chain reaction; fluconazole; molecular docking simulation; multivariate analysis
Online: 11 October 2023 (12:24:15 CEST)
ARTICLE
|
doi:10.20944/preprints202305.0723.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
retina organ culture; neuroretinal degenerative disease; oxidative stress; antioxidant; age-related macular degeneration (AMD); diabetic retinopathy (DR); Scutellarin; PEDF; GM-CSF; 4R
Online: 10 May 2023 (09:42:33 CEST)
REVIEW
|
doi:10.20944/preprints201807.0241.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
biomaterial; bone regeneration; drug release; hydrogel; lignin; multivariate data processing; osteogenesis; scaffolds; stem cells; tissue engineering
Online: 13 July 2018 (15:07:37 CEST)
ARTICLE
|
doi:10.20944/preprints202301.0221.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
Ion channels; Membrane proteins; Transmembrane proteins; Drug discovery; Protein language models; Convolutional Neural Network
Online: 12 January 2023 (09:21:08 CET)
REVIEW
|
doi:10.20944/preprints202308.1547.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Main Protease Inhibitors; SARS-CoV-2; COVID-19; mutations; vaccines; therapeutics; drug repurposing; management strategies
Online: 22 August 2023 (09:31:05 CEST)
REVIEW
|
doi:10.20944/preprints202008.0320.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
Data Science; Machine Learning; Deep Learning; Genomics; COVID-19; Drug Discovery; Image Analysis; Interactomics; Epidemiology
Online: 14 August 2020 (11:01:56 CEST)
ARTICLE
|
doi:10.20944/preprints202301.0120.v1
Subject:
Social Sciences,
Psychology
Keywords:
work-related rumination; overcommitment; psychological detachment; burnout; irritation; problem-solving pondering; positive work reflection; negative work reflection; affective rumination; satisfaction with life
Online: 6 January 2023 (09:36:21 CET)
ARTICLE
|
doi:10.20944/preprints202408.0351.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
Composite hydrogel; encapsulated cell therapy; neuroprotection; sustained drug delivery; retina
Online: 6 August 2024 (12:41:08 CEST)
ARTICLE
|
doi:10.20944/preprints202407.1888.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Keywords: Coronavirus; 3CL protease; Drug target for Coronavirus; SARS-CoV
Online: 24 July 2024 (12:36:54 CEST)
REVIEW
|
doi:10.20944/preprints202407.1270.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
Enterovirus; Multi-target directed ligand; Clinical Trials; Combination; Drug design
Online: 16 July 2024 (08:27:11 CEST)
REVIEW
|
doi:10.20944/preprints202405.1419.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
hydrogel; smart hydrogel; brain tumor; drug delivery systems; local treatment
Online: 22 May 2024 (09:29:34 CEST)
ARTICLE
|
doi:10.20944/preprints202311.1938.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
drug-induced allergy; anaphylaxis; antibiotics; local anesthetics; cyclooxygenase (COX)-inhibitors
Online: 30 November 2023 (04:21:45 CET)
REVIEW
|
doi:10.20944/preprints202309.0152.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cytochromes P450; ovarian cancer; gynecologic cancers; pro-drug; xenobiotics; prognosis
Online: 4 September 2023 (11:58:30 CEST)
REVIEW
|
doi:10.20944/preprints202308.2059.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
M.tb pathogenesis; MDR-TB; XDR-TB; drug tolerance; new approaches
Online: 30 August 2023 (11:20:12 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0264.v1
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
firocoxib; coagulation; gastroscopy; hematology; selective COX-2 Inhibitor; drug safety
Online: 3 August 2023 (10:27:17 CEST)
ARTICLE
|
doi:10.20944/preprints202306.2085.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
coronary artery disease; drug-coated balloon; in-stent restenosis; predictors
Online: 29 June 2023 (09:22:50 CEST)
REVIEW
|
doi:10.20944/preprints202304.0697.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
viral vectors; gene therapy; animal models; clinical trials; drug approval
Online: 21 April 2023 (08:55:15 CEST)
ARTICLE
|
doi:10.20944/preprints202302.0314.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
Electrospinning; Nanofibers; Polycaprolactone; Plantago Major L; Drug delivery; Wound dressing
Online: 20 February 2023 (01:32:00 CET)
ARTICLE
|
doi:10.20944/preprints202211.0530.v1
Subject:
Computer Science And Mathematics,
Applied Mathematics
Keywords:
Brain Diseases; Blood-Brain Barrier; Magnetic Field; Nanoparticle; Drug Delivery
Online: 29 November 2022 (03:34:14 CET)
ARTICLE
|
doi:10.20944/preprints202208.0066.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
Mesoporous silica; Polyacrylic acid; Calcium ion; 5-Fluorouracil; Drug delivery
Online: 2 August 2022 (12:15:03 CEST)
REVIEW
|
doi:10.20944/preprints202206.0147.v3
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Designed Ankyrin Repeat protein; DARPin; drug development; ensovibep; abicipar pegol
Online: 21 June 2022 (10:21:27 CEST)
REVIEW
|
doi:10.20944/preprints202203.0237.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
academy; drug development; industrial pharmacy; pharmaceutical technology; research method-ology
Online: 17 March 2022 (01:56:47 CET)
ARTICLE
|
doi:10.20944/preprints202111.0329.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Machine Learning; Deep Learning; Molecular Modeling; Virtual Screening; Drug Discovery
Online: 18 November 2021 (13:59:09 CET)
REVIEW
|
doi:10.20944/preprints202108.0558.v1
Subject:
Chemistry And Materials Science,
Polymers And Plastics
Keywords:
chitosan; chitin; biological activit; drug delivery; antioxidant; antimicrobial; biocatalysis; nanoparticles
Online: 31 August 2021 (11:07:28 CEST)
ARTICLE
|
doi:10.20944/preprints202107.0395.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Melatonin; molecular modelling; adsorption; clays; modified drug release; molecular dynamics
Online: 19 July 2021 (08:44:04 CEST)
REVIEW
|
doi:10.20944/preprints202103.0095.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
doxorubicin; drug delivery; polymers; targeted therapy; anticancer treatment; controlled release
Online: 2 March 2021 (14:14:38 CET)
REVIEW
|
doi:10.20944/preprints202102.0405.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
drug repurposing; antifungal therapy; antifungal mechanism; clinical application; antifungal agents
Online: 18 February 2021 (10:21:38 CET)
REVIEW
|
doi:10.20944/preprints202010.0159.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Thyroid carcinoma; non-coding RNA; radioactive iodine; drug resistance; prognosis
Online: 7 October 2020 (14:28:40 CEST)
ARTICLE
|
doi:10.20944/preprints202010.0138.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Mass drug administration; Azithromycin; Gut microbiota; V4-16S rRNA sequencing
Online: 6 October 2020 (15:55:40 CEST)
ARTICLE
|
doi:10.20944/preprints202009.0745.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
Biodegradable polymers; Nanoparticles; Cancer chemotherapy; Controlled release; Drug delivery systems
Online: 30 September 2020 (12:47:17 CEST)
REVIEW
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
cannabis; cannabinergic; drug; FDA-approved; medical conditions; pharmaceutical-grade; phytocannabinoid
Online: 31 August 2020 (10:38:32 CEST)
REVIEW
|
doi:10.20944/preprints202005.0029.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
COVID-19; Cytokine Storm; Lung Injury; Thalidomide; Anti-inflammatory Drug
Online: 3 May 2020 (07:31:53 CEST)
ARTICLE
|
doi:10.20944/preprints202003.0360.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
SARS-CoV-2; transcriptional inhibition; COVID-19; drug repurposing; TMPRSS2
Online: 28 April 2020 (09:39:02 CEST)
ARTICLE
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
USP14; molecular docking; molecular dynamic simulation; cancer; ubiquitin; drug discovery
Online: 23 December 2019 (12:36:38 CET)
ARTICLE
|
doi:10.20944/preprints201910.0074.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Pseudomonas aeruginosa; Quorum sensing; Virtual screening; E-pharmacophore; Drug discovery.
Online: 7 October 2019 (12:33:33 CEST)
ARTICLE
|
doi:10.20944/preprints201904.0075.v1
Subject:
Chemistry And Materials Science,
Applied Chemistry
Keywords:
amphiphilc copolymer; hydrolyzable polyurea; micelle; controlled drug delivery; cancer chemotherapy
Online: 8 April 2019 (08:35:46 CEST)
REVIEW
|
doi:10.20944/preprints201901.0273.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Mycobacterium abscessus; non-tuberculous mycobacteria; antimicrobial drug discovery; cystic fibrosis
Online: 28 January 2019 (10:05:28 CET)
REVIEW
|
doi:10.20944/preprints201810.0701.v2
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
tuberculosis; latency; non-replicating persistent; antibiotic; drug discovery; mycobacterium tuberculosis
Online: 14 November 2018 (10:24:31 CET)
ARTICLE
|
doi:10.20944/preprints201810.0697.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
glioma; glioblastoma; pre-clinical drug development; 3D culture systems; radiotherapy
Online: 30 October 2018 (03:38:28 CET)
REVIEW
|
doi:10.20944/preprints201810.0360.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Molecular Dynamics, CoSolvent Molecular Dynamics, Drug design, Fragment Screening, Docking
Online: 16 October 2018 (12:15:17 CEST)
ARTICLE
|
doi:10.20944/preprints202005.0397.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
SARS-CoV-2; Drug repurposing; N-acetyl-D-glucosamine; ORF1ab; Biodata mining; Protein modelling
Online: 24 May 2020 (18:49:41 CEST)
ARTICLE
|
doi:10.20944/preprints202306.0723.v1
Subject:
Medicine And Pharmacology,
Complementary And Alternative Medicine
Keywords:
Synergistic effect; Antibiotic resistance; Medicinal Plants; Penicillin G; Sutherlandia Frutescens; Microbial sensitivity tests; Drug combinations
Online: 9 June 2023 (13:09:26 CEST)
COMMUNICATION
|
doi:10.20944/preprints202212.0060.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
exosomes; extrusion; proteolipid nanoparticles; drug delivery; nanomedicine; doxorubicin; ex-truded nanoparticles; hydroxychloroquine; endolysosomal escape; lysosomotropic
Online: 5 December 2022 (06:04:21 CET)
ARTICLE
|
doi:10.20944/preprints201901.0046.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Keywords: methotrexate, cubic phase, magnetocubosomes, monoolein, liquid crystalline phase, drug delivery system, alternating magnetic field
Online: 4 January 2019 (14:32:38 CET)
COMMUNICATION
|
doi:10.20944/preprints202002.0421.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
De novo transcriptome assembly; brushtail possums; liver; brain cerebral cortex; drug and xenobiotic metabolism; chemical toxicants
Online: 28 February 2020 (11:49:29 CET)
ARTICLE
|
doi:10.20944/preprints202307.1220.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
age-related macular degeneration; aging retina; peroxisome proliferator-activated receptor gamma coactivator 1-alpha; PGC-1 AMD; cellular senescence; autophagy; oxidative stress
Online: 18 July 2023 (11:09:42 CEST)
ARTICLE
|
doi:10.20944/preprints202205.0256.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Extracellular matrices; Macromolecular crowding; human iPSC derived astrocytes; human iPSC derived dopaminergic neurons; drug testing
Online: 19 May 2022 (08:50:28 CEST)
ARTICLE
|
doi:10.20944/preprints202203.0117.v3
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
active pharmaceutical ingredient; compounded drug; compounding; extemporaneous formulation; manufactured material; medication; monograph; pediatric; reference standards
Online: 5 April 2022 (10:17:10 CEST)
ARTICLE
|
doi:10.20944/preprints202112.0122.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
hepatitis B virus; besifovir dipivoxil maleate (BSV); nucleos(t)ide analog; drug resistance; reverse transcription
Online: 8 December 2021 (12:06:52 CET)
REVIEW
|
doi:10.20944/preprints202207.0141.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
review; real -world evidence; real -world data; randomized controlled trials; registry; digital health technology; early drug approval
Online: 8 July 2022 (11:09:58 CEST)
ARTICLE
|
doi:10.20944/preprints202408.2166.v1
Subject:
Computer Science And Mathematics,
Information Systems
Keywords:
Digital health; climate health; environmental health; public health; mobile health applications; community engagement; climate-related health risks
Online: 29 August 2024 (12:31:10 CEST)
ARTICLE
|
doi:10.20944/preprints201906.0020.v1
Subject:
Environmental And Earth Sciences,
Geochemistry And Petrology
Keywords:
REE distribution pattern; REE fluid-melt partition coefficient; granite; intrusion-related gold system; porphyry copper (gold) system
Online: 3 June 2019 (12:16:38 CEST)
ARTICLE
|
doi:10.20944/preprints201704.0016.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
periodontitis; the periodontal ligament stem cells; the nuclear factor-erythroid 2-related factor 2; oxidative stress; apoptosis
Online: 4 April 2017 (08:58:13 CEST)
ARTICLE
|
doi:10.20944/preprints202304.0110.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Information; matter-related information; micro/macro structuration/destructuration; non-living/living structures; Informational Model of the Human Body and Living Structures; Infor-mational Model of Consciousness
Online: 7 April 2023 (03:56:25 CEST)
REVIEW
|
doi:10.20944/preprints202407.0821.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
Nanogels; nanoparticle synthesis; hydrogels and microgels; batch chemistry; flow chemistry; microfluidics; nanomedicine; theranostics; cross-linking; drug delivery
Online: 10 July 2024 (05:08:20 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0141.v1
Subject:
Chemistry And Materials Science,
Materials Science And Technology
Keywords:
A549 lung cancer; nanoparticles; cell-penetration, drug affinity, dissociation constants; molecular docking; antibacterial; hydroxychloroquine
Online: 2 August 2023 (04:54:14 CEST)
ARTICLE
|
doi:10.20944/preprints202403.0565.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
Two-dimensional liquid chromatography; heart-cutting 2D-LC; veterinary drug residue; nucleotides monophosphate; sheep’s milk
Online: 11 March 2024 (08:59:00 CET)
REVIEW
|
doi:10.20944/preprints202401.0524.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
transdermal drug delivery system; skin permeation; permeation enhancers; quality by design ap-proach; therapeutic applications
Online: 8 January 2024 (06:41:04 CET)
REVIEW
|
doi:10.20944/preprints202309.0207.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Neglected tropic diseases; Parasites; Chagas disease; Leishmaniasis; Life cycle; Drug target; Biochemical mechanisms; Pharmacological therapeutics; Peptides
Online: 6 September 2023 (14:52:33 CEST)
ARTICLE
|
doi:10.20944/preprints202111.0395.v1
Subject:
Chemistry And Materials Science,
Physical Chemistry
Keywords:
Tamarind Gum; Hydrogels; Semi-IPNs; Green synthesis; Silver Nanoparticles; Drug Delivery; Chemotherapeutics; HCT116 Cell; Anti-microbial
Online: 22 November 2021 (13:46:47 CET)
REVIEW
|
doi:10.20944/preprints202001.0353.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
chromothripsis; structural variants; DNA-repair; DNA-repair disorders; DNA-double strand breaks (DSBs); ataxia telangiectasia mutated (ATM); ataxia-telangiectasia and Rad3-related (ATR); TP53; micronuclei; chromosome pulverization.
Online: 29 January 2020 (11:58:58 CET)
ARTICLE
|
doi:10.20944/preprints202402.0156.v1
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
antimicrobial resistance; biosecurity; dairy calves; ESBL E. coli; multi-drug resistant; waste milk
Online: 2 February 2024 (14:20:05 CET)
ARTICLE
|
doi:10.20944/preprints201809.0513.v1
Subject:
Medicine And Pharmacology,
Tropical Medicine
Keywords:
Malawi, HIV, tuberculosis, anti-retroviral therapy, surveillance, patient monitoring, epidemic trends, drug supply, unique patient identifiers, data analysis
Online: 27 September 2018 (15:29:43 CEST)
ARTICLE
|
doi:10.20944/preprints201809.0544.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
Bodybuilding; Drug Free; Competing; Peaking; Carbohydrate Loading; Water Loading; Sodium Loading; Fat Loading: Vitamin C; Fibre Restriction
Online: 27 September 2018 (12:58:34 CEST)
ARTICLE
|
doi:10.20944/preprints202307.1647.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
non-steroidal anti-inflammatory drug; stroke; acute coronary syndrome; myocardial infarction; mortality; readmission; Arabian Gulf
Online: 25 July 2023 (08:26:22 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0492.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Drug resistance; nsp12; protein design; fitness; RNA-dependent RNA polymerase; resistance mutations; SARS-CoV-2.
Online: 20 May 2021 (13:18:14 CEST)
REVIEW
|
doi:10.20944/preprints201910.0296.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
nasal delivery; glioblastoma multiforme; drug delivery; nanoparticles; nose-to-brain delivery; pre-clinical studies; clinical evaluation
Online: 27 October 2019 (09:36:27 CET)
REVIEW
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
metabolic functionalization of alkyl moieties in drug molecules; structure influence on metabolic functionalization of alkyl moieties; mechanism of alkyl free radical hydroxy functionalization; pharmacologic activity of hydroxy and carboxy functionalized alkyl moieties in drug molecules; primary and auxiliary pharmacophores; auxophores
Online: 11 March 2020 (03:20:58 CET)
REVIEW
|
doi:10.20944/preprints202305.0289.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
cancer therapy; nanomedicine; drug delivery; pH-responsiveness; EPR; intratumoral delivery; intracellular delivery; nanoparticles; metal-organic frameworks
Online: 5 May 2023 (03:45:54 CEST)
ARTICLE
|
doi:10.20944/preprints202205.0392.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
atrial-fibrillation; multi-target; drug promiscuity; druggable binding site; flecainide; Nav1.5; Kv1.5; binding site comparison; polypharmacology
Online: 30 May 2022 (10:10:41 CEST)
REVIEW
|
doi:10.20944/preprints202102.0619.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Nanotechnology 1; Nanomedicine 2; organic and inorganic nanoparticles 3; drug delivery 4; antitumour therapy5; tissue engineering 6.
Online: 26 February 2021 (13:31:45 CET)
ARTICLE
|
doi:10.20944/preprints202101.0490.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
CD44; Cancer Stem Cells; Tumorigenesis; Drug Resistance; Immune Markers; Epithelial to Mesenchymal Transition; Therapeutic Targeting
Online: 25 January 2021 (12:23:49 CET)
REVIEW
|
doi:10.20944/preprints202407.1534.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
lymphoma; B‐cell; hematologic neoplasms; bruton tyrosine kinase; protein kinase inhibitors; drug resistance; neoplasm; ibrutinib; pirtobrutinib; molecular targeted therapy; chronic lymphocytic leukemia; hematopoietic stem cell transplantation; covalent inhibitors; protein degradation
Online: 18 July 2024 (17:24:05 CEST)
REVIEW
|
doi:10.20944/preprints202408.0053.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
thrombotic disorders; targeted-antithrombotic approaches; nanothrombolysis; clot-penetrating drug; aging; fibrinolysis
Online: 2 August 2024 (03:57:37 CEST)
ARTICLE
|
doi:10.20944/preprints202402.0233.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
depression; adolescent girls; National Survey on Drug Use and Health; pandemic
Online: 5 February 2024 (07:56:24 CET)
REVIEW
|
doi:10.20944/preprints202402.0117.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
nanomedicine; biomimicry; biomimetic nanoparticle; targeted drug delivery; homotypic targeting; nanoparticle coating
Online: 2 February 2024 (07:25:29 CET)
SHORT NOTE
|
doi:10.20944/preprints202312.0899.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
monoamine oxidase; inhibitors; 1,3-oxazole; benzenesulfonamide; drug research; Parkinson’s disease; MAO
Online: 12 December 2023 (14:22:48 CET)
ARTICLE
|
doi:10.20944/preprints202312.0540.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
c-FLIP; TRAIL; apoptosis; protein-protein interaction; drug resistance; cancer treatment
Online: 7 December 2023 (14:37:18 CET)
ARTICLE
|
doi:10.20944/preprints202310.0918.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
drug sensitivity scores; molecular modeling; molecular docking; four-parameter logistic curve
Online: 16 October 2023 (11:38:46 CEST)
ARTICLE
|
doi:10.20944/preprints202308.2158.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Ebola virus; measles virus; VP35; PKR; PACT; RIG-I; drug screen.
Online: 31 August 2023 (08:42:45 CEST)
ARTICLE
|
doi:10.20944/preprints202306.1076.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
Thymoquinone; SBE-β-CD; Leukemia; Drug delivery system; Telomerase inhibition; Apoptosis
Online: 15 June 2023 (05:37:50 CEST)
ARTICLE
|
doi:10.20944/preprints202306.0257.v1
Subject:
Medicine And Pharmacology,
Dermatology
Keywords:
wound dressing; drug delivery; organ culture, infection models, ciprofloxacin, infected wounds
Online: 5 June 2023 (08:09:29 CEST)
ARTICLE
|
doi:10.20944/preprints202306.0109.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
triple negative breast cancer; MCAK/KIF2C; aneuploidy; chromosomal instability; drug discovery
Online: 1 June 2023 (15:47:29 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1693.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
Digital twin; Clinical trials; Quality by Design; Blockchain technology; Drug development
Online: 24 May 2023 (04:46:13 CEST)