REVIEW
|
doi:10.20944/preprints202012.0675.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Breast cancer; Estrogen Receptor; PI3K-AKT-mTOR; anti-estrogen resistance
Online: 28 December 2020 (09:22:17 CET)
REVIEW
|
doi:10.20944/preprints202307.1695.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
hepatocellular carcinoma; EGFR/PI3K/AKT/mTOR signaling; animal models; Targeted Therapy
Online: 26 July 2023 (10:07:16 CEST)
ARTICLE
|
doi:10.20944/preprints201706.0120.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
sinulariolide; human bladder cancer; migration; invasion; PI3K/AKT/mTOR signaling pathway
Online: 27 June 2017 (06:23:44 CEST)
REVIEW
|
doi:10.20944/preprints202408.1919.v2
Subject:
Life Sciences,
Biology And Life Sciences
Keywords:
Cancer; Diabetes; Obesity; Inflammation; Apoptosis; Akt inhibitors; mTOR inhibitors; PI3K/Akt/mTOR signaling
Online: 28 August 2024 (10:45:50 CEST)
ARTICLE
|
doi:10.20944/preprints202305.0844.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Peptidomimetic; VEGFR2; Angiogenesis; Tumor suppression; PI3K/Akt/mTOR signaling pathway; PLCγ/ERK signaling pathway
Online: 11 May 2023 (10:57:38 CEST)
ARTICLE
|
doi:10.20944/preprints201807.0297.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
24-methylenecycloartanyl ferulate, angiogenesis, PPAR-γ2, PPRE, Akt/mTOR, HoxA7, VEGF, LIF, HUVEC
Online: 17 July 2018 (09:10:14 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Metformin; cerebralischemia-reperfusion; inflammation; PI3K/Akt.
Online: 12 March 2021 (08:43:06 CET)
ARTICLE
|
doi:10.20944/preprints201612.0042.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
acute lung injury; mycelium of Sanghuangporus sanghuang; lipopolysaccharide; KAP1/Nrf2 pathway; PI3K/Akt/mTOR pathways; HO-1; HNGB1
Online: 7 December 2016 (11:15:30 CET)
ARTICLE
|
doi:10.20944/preprints202008.0112.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
AKT/PI3K signaling pathway; apoptosis; human hepatocarcinoma HepG2 cells; migration activity; proliferation; oxidative stress; ROS level; uvaol
Online: 5 August 2020 (05:58:26 CEST)
REVIEW
|
doi:10.20944/preprints202401.1992.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
MLIP; Cancer; PI3 kinase; Akt; mTOR; Tumorigenesis
Online: 29 January 2024 (05:47:34 CET)
ARTICLE
|
doi:10.20944/preprints202408.0566.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Corilagin; Ovarian cancer; apoptosis; PI3K-AKT; signal pathway
Online: 8 August 2024 (17:13:59 CEST)
ARTICLE
|
doi:10.20944/preprints202101.0232.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
CaSR; Homer1; mTOR; osteoblast; osteocyte; AKT; chaperone function
Online: 12 January 2021 (17:21:02 CET)
REVIEW
|
doi:10.20944/preprints202105.0367.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
PI3K/mTOR signalling; feedback loop; crosstalk; nonlinear dynamics; cancer
Online: 17 May 2021 (07:54:13 CEST)
REVIEW
|
doi:10.20944/preprints202106.0333.v2
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
2-Deoxyglucose; Adverse effects; COVID-19; Glutamine; PI3K/Akt
Online: 1 July 2021 (13:04:43 CEST)
ARTICLE
|
doi:10.20944/preprints201808.0043.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
cryptotanshinone; NSCLC; cell cycle arrest; apoptosis; PI3K/Akt/GSK3β
Online: 2 August 2018 (09:05:32 CEST)
ARTICLE
|
doi:10.20944/preprints201807.0065.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
hypothalamus; insulin resistance; inflammation; docosahexaenoic acid; PI3K inhibitor; AKT
Online: 4 July 2018 (09:58:03 CEST)
REVIEW
|
doi:10.20944/preprints202307.1284.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Cancer; tumourigenesis; drug resistance; signalling pathways; Wnt/β-catenin pathway; JAK/STAT pathway; PI3K/Akt/mTOR pathway; RAS/RAF/MAPK/ERK signalling
Online: 19 July 2023 (09:14:02 CEST)
ARTICLE
|
doi:10.20944/preprints201809.0153.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
diabetic nephropathy; exosomes; autophagy; mTOR
Online: 10 September 2018 (06:26:55 CEST)
ARTICLE
|
doi:10.20944/preprints202405.1890.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Parecoxib; 5-fluorouracil; Colorectal cancer; Metastasis; Reactive oxygen species; PI3K/Akt pathway
Online: 28 May 2024 (17:00:53 CEST)
REVIEW
|
doi:10.20944/preprints202310.1483.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
AR; TNBC; CDK4/6; CYP17 lyase; PI3K/AKT; ER; PR; HER2; DHT
Online: 24 October 2023 (05:51:15 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1949.v2
Subject:
Biology And Life Sciences,
Toxicology
Keywords:
Methamphetamine; BDNF; CREB; Akt-1; GSK3; Amygdala
Online: 20 September 2023 (03:22:53 CEST)
REVIEW
|
doi:10.20944/preprints202306.0952.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
mTOR; CD8 T cell; NK cell; cytokine signaling
Online: 13 June 2023 (15:45:23 CEST)
REVIEW
|
doi:10.20944/preprints202404.0203.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
cold plasma; plasma-activated water; redox signalling; cancer; wound healing; Nrf2; MAPK; PI3K/Akt; endoplasmic reticulum stress
Online: 2 April 2024 (12:22:07 CEST)
ARTICLE
|
doi:10.20944/preprints202301.0129.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
chondrogenesis; cartilage; col11a1; collagen α1(XI), AKT; GSK3b; Wnt; ATDC5
Online: 7 January 2023 (13:00:05 CET)
ARTICLE
|
doi:10.20944/preprints202307.1464.v1
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
bovine skeletal muscle satellite cells; sodium butyrate; mitophagy; apoptosis; mTOR signaling pathway
Online: 21 July 2023 (05:18:58 CEST)
ARTICLE
|
doi:10.20944/preprints202311.0013.v1
Subject:
Biology And Life Sciences,
Toxicology
Keywords:
Bisphenol A; Bisphenol S; Bisphenol F; Atopic dermatitis; DNA methylation; JAK-STAT signaling pathway; PI3K-AKT signaling pathway
Online: 1 November 2023 (04:02:06 CET)
REVIEW
|
doi:10.20944/preprints202308.0444.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Avenanthramide; AKT-Protein kinase B; Alzheimer's disease; Parkinson's disease; oxidative stress; neuroprotection
Online: 7 August 2023 (02:28:52 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1804.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
EVs; Macrophages 1; STAT3, AKT; NF-κB; metastasis; colorectal cancer.
Online: 25 May 2023 (10:48:17 CEST)
ARTICLE
|
doi:10.20944/preprints202004.0053.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
calcium signaling; chemokine signaling; gap junction; NOD-like receptor signaling; oli-neu cells; pannexin1; PI3K-Akt pathway; thyroid hormone pathway
Online: 6 April 2020 (12:36:20 CEST)
REVIEW
|
doi:10.20944/preprints202112.0518.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
B-cell non-Hodgkin lymphoma (B-NHL); B-cell receptor (BCR); Bruton’s tyrosine kinase (BTK); spleen tyrosine kinase (SYK); phosphoinositide-3-kinase (PI3K); ibrutinib; acalabrutinib; copanlisib; idelalisib; umbralisib; fostamatinib; combination therapies
Online: 31 December 2021 (12:23:29 CET)
REVIEW
|
doi:10.20944/preprints202306.1251.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
mTOR; gut microbes; metabolites; therapy
Online: 16 June 2023 (14:02:23 CEST)
ARTICLE
|
doi:10.20944/preprints201806.0083.v1
Subject:
Medicine And Pharmacology,
Anesthesiology And Pain Medicine
Keywords:
anesthesia; neurotoxicity; synapse; mTOR; neurodevelopment
Online: 6 June 2018 (10:36:51 CEST)
ARTICLE
|
doi:10.20944/preprints202402.0866.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
cancer; PI3K; HDAC6; cytotoxicity; antiproliferative; synergism; DMPK
Online: 15 February 2024 (15:35:47 CET)
ARTICLE
|
doi:10.20944/preprints202402.0503.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
HNSCC; PI3K inhibitors; ErbB inhibitor; targeted therapy
Online: 8 February 2024 (14:11:24 CET)
ARTICLE
|
doi:10.20944/preprints202406.1966.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Akt; cell death; GAPDH; ischemia-like insult; neuroprotection; Nrf2; phosphorylation; Rasagiline; ROS; PC 12 neuronal model; α-synuclein; Parkinson’s disease; stroke
Online: 1 July 2024 (08:40:53 CEST)
ARTICLE
|
doi:10.20944/preprints202212.0011.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
MST4; EMT; AKT; Apoptosis; Breast cancer
Online: 1 December 2022 (04:46:12 CET)
ARTICLE
|
doi:10.20944/preprints202106.0443.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
miR-378d; ESCC; AKT; RhoA; polyploidization
Online: 16 June 2021 (12:07:30 CEST)
REVIEW
|
doi:10.20944/preprints201806.0056.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
mTOR; mTORC1; mTORC2; rapamycin; rapalogues; rapalogs; mTOR inhibitors; senescence; ageing; aging; cancer; neurodegeneration; immunosenescence; senolytics; biomarkers
Online: 5 June 2018 (09:49:19 CEST)
REVIEW
|
doi:10.20944/preprints201911.0170.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
PI3K signalling; cancer; stemness; pluripotent stem cells; development
Online: 15 November 2019 (03:59:00 CET)
ARTICLE
|
doi:10.20944/preprints202203.0001.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
CMT1E; Trembler-J; curcumin; Hsps; autophagy; mTOR
Online: 1 March 2022 (02:52:34 CET)
REVIEW
|
doi:10.20944/preprints202102.0278.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
ncRNA; miR; NCDs; onco-miR; cancer; mTOR
Online: 11 February 2021 (11:04:50 CET)
REVIEW
|
doi:10.20944/preprints202004.0530.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
CDK1; eIF4F; mTOR; mRNA translation; M-phase
Online: 30 April 2020 (13:46:44 CEST)
REVIEW
|
doi:10.20944/preprints202309.0682.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Akt; cancer; metastasis; HNSCC; EMT; cytoskeletal remodelling
Online: 12 September 2023 (08:33:01 CEST)
ARTICLE
|
doi:10.20944/preprints202112.0023.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Cancer; neurodegeneration; glioma; Drosophila; disease model; PI3K; EGFR; genetics
Online: 2 December 2021 (09:30:17 CET)
REVIEW
|
doi:10.20944/preprints202312.1388.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Rheb1; Rheb2; Cancer; mTOR; Hallmarks; Neurons; Rheb1 inhibitors
Online: 19 December 2023 (05:58:46 CET)
ARTICLE
|
doi:10.20944/preprints202312.1030.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Marrow failure; mitochondria; SRSF4; mTOR; CLUH; DRP1; OPA1
Online: 14 December 2023 (08:07:53 CET)
BRIEF REPORT
|
doi:10.20944/preprints202306.1357.v1
Subject:
Medicine And Pharmacology,
Reproductive Medicine
Keywords:
mTOR; rapamycin; PRP; platelet cytokines; ovarian reserve; IVF
Online: 19 June 2023 (12:55:06 CEST)
ARTICLE
|
doi:10.20944/preprints202304.0797.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Heart failure; Malnutrition; Exercise; Amino-acids; mTOR; Deptor
Online: 23 April 2023 (08:45:26 CEST)
HYPOTHESIS
|
doi:10.20944/preprints202110.0373.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Zika virus; Microcephaly; Neurogenesis; Retinoic Acid; mTOR signaling
Online: 26 October 2021 (11:12:37 CEST)
ARTICLE
|
doi:10.20944/preprints202110.0003.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
AP5M1; BAIAP2L1; ENTPD2; MTOR; AKT2; FKBP9; TBRG4; TMEM186
Online: 1 October 2021 (11:16:39 CEST)
ARTICLE
|
doi:10.20944/preprints201805.0076.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Oral cancer; mTOR pathway; secreted glycoprotein; drug resistance
Online: 3 May 2018 (12:47:14 CEST)
ARTICLE
|
doi:10.20944/preprints201801.0144.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
MMP-1, EGFR-TKI resistance, lung adenocarcinoma, mTOR
Online: 16 January 2018 (13:57:04 CET)
ARTICLE
|
doi:10.20944/preprints202310.0878.v1
Subject:
Biology And Life Sciences,
Other
Keywords:
AKT; cold atmospheric plasma; ERK; miRNA; oral carcinoma
Online: 13 October 2023 (10:04:03 CEST)
ARTICLE
|
doi:10.20944/preprints202001.0255.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Cordycepin; Cisplatin-resistance; Resensitization; MDR1; Ets-1; AKT
Online: 22 January 2020 (09:18:20 CET)
REVIEW
|
doi:10.20944/preprints201805.0125.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
dimerization; miRNA; motility; anoikis; chaperon; PTEN; FIP200; LKB1; PI3K; regulation
Online: 8 May 2018 (09:07:58 CEST)
REVIEW
|
doi:10.20944/preprints202406.0642.v1
Subject:
Biology And Life Sciences,
Other
Keywords:
Energy; entropy; protein synthesis; amino acids; autophagy; AMPK; mTOR
Online: 11 June 2024 (08:31:10 CEST)
ARTICLE
|
doi:10.20944/preprints202311.0851.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Estrogen receptor a; sigma receptors; TMEM97; mTOR; S6K1; tamoxifen.
Online: 14 November 2023 (09:28:12 CET)
ARTICLE
|
doi:10.20944/preprints202302.0250.v1
Subject:
Medicine And Pharmacology,
Other
Keywords:
AI drug discovery; mTOR; rapalog; C. elegans; cancer; longevity
Online: 15 February 2023 (02:42:57 CET)
ARTICLE
|
doi:10.20944/preprints201901.0018.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
pyruvate kinase M2; prostate cancer; cancer metabolism; mTOR; autophagy
Online: 3 January 2019 (12:32:52 CET)
ARTICLE
|
doi:10.20944/preprints202308.0641.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
licochalcone H (LCH); oxaliplatin; colorectal cancer; EGFR; AKT; apoptosis
Online: 9 August 2023 (03:01:44 CEST)
ARTICLE
|
doi:10.20944/preprints202005.0514.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
AKT; D-Pinitol; ghrelin; insulin; insulin resistance; liver; phosphorylation
Online: 31 May 2020 (21:11:01 CEST)
ARTICLE
|
doi:10.20944/preprints202004.0312.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
chalocomoracin; proliferative vitreoretinopathy; vitreous; Akt; p53; migration; proliferation; contraction
Online: 19 April 2020 (02:18:01 CEST)
REVIEW
|
doi:10.20944/preprints201907.0256.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
PI 3-kinase; chromosomal instability; PI3K inhibitor; cancer; tumour evolution; centrosome
Online: 23 July 2019 (11:01:34 CEST)
ARTICLE
|
doi:10.20944/preprints201802.0013.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
pancreatic cancer; proteomics; PI3K pathway; precision medicine; predictor of therapeutic response
Online: 2 February 2018 (06:57:47 CET)
REVIEW
|
doi:10.20944/preprints201802.0011.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Pancreatic cancer, proteomics, PI3K pathway, precision medicine, predictor of therapeutic response
Online: 1 February 2018 (17:16:04 CET)
ARTICLE
|
doi:10.20944/preprints202304.0254.v1
Subject:
Biology And Life Sciences,
Toxicology
Keywords:
cancer cells; quinones; mTOR; antiproliferative activity; molecular descriptors; molecular docking
Online: 12 April 2023 (07:57:34 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Vericiguat; osteoclast (OCs), MAPK, NF-κB; RANKL; AKT, molecular mechanism
Online: 8 September 2021 (13:02:05 CEST)
ARTICLE
|
doi:10.20944/preprints202001.0109.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Alzheimer’s disease; curcumin; network pharmacology; molecular simulation; neurodegeneration; TrkB/PI3K signaling; autophagy
Online: 11 January 2020 (13:53:12 CET)
REVIEW
|
doi:10.20944/preprints201904.0127.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
PTEN; PI3K; cancer predisposition syndromes; targeted therapies; mouse models of human cancer
Online: 10 April 2019 (10:37:43 CEST)
ARTICLE
|
doi:10.20944/preprints202306.1949.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
homocysteine thiolactone; N-homocysteinylated protein; microRNA; PHF8; mTOR; autophagy; endothelial cells
Online: 28 June 2023 (07:08:26 CEST)
REVIEW
|
doi:10.20944/preprints202210.0230.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
PBDE; dose-response relationships; mTOR signaling; steroidogenesis; metabolic disruption; sperm epigenome
Online: 17 October 2022 (05:37:53 CEST)
REVIEW
|
doi:10.20944/preprints201905.0358.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
alloimmune response; immunosuppressants; calcineurin inhibitors; corticosteroids; mTOR inhibitors; neurotoxicity; neuroprotective effects
Online: 29 May 2019 (16:37:44 CEST)
REVIEW
|
doi:10.20944/preprints201801.0148.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
DCP-LA; PKCε; protein tyrosine phosphatase 1B; Akt; GSK-3β; tauopathy
Online: 17 January 2018 (05:26:21 CET)
ARTICLE
|
doi:10.20944/preprints201609.0074.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
hepatocellular carcinoma; hepatitis B virus X protein; Notch1 pathway; ERK; AKT
Online: 21 September 2016 (09:49:13 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1752.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Intracerebroventricular, ICV; mTOR, mTOR-I, rapalog; Tuberous Sclerosis, TSC; Multiple Sclerosis, MS; Experimental Autoimmune Encephalitis, EAE; Alzheimer’s Disease, AD; Thermostable Micelles, Micellar Liquid Formulation; Ommaya device
Online: 24 August 2023 (12:53:26 CEST)
REVIEW
|
doi:10.20944/preprints202010.0195.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Autophagy; Amyloid precursor protein (APP); β‐amyloid (Aβ); mTOR; Alzheimer’s disease (AD).
Online: 9 October 2020 (11:07:53 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1194.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Breast cancer; obesity; metabolic syndrome; rat model; DMBA; insulin signaling; PI3/Akt
Online: 17 May 2023 (05:25:25 CEST)
ARTICLE
|
doi:10.20944/preprints202008.0572.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
glycine soja seed; type 2 diabetes mellitus; antidiabetic; AMPK; Akt; PPAR-γ
Online: 26 August 2020 (09:16:38 CEST)
ARTICLE
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
Glycine soja seed; Type 2 diabetes mellitus; Antidiabetic; AMPK; Akt; PPAR-γ
Online: 25 August 2020 (11:47:20 CEST)
ARTICLE
|
doi:10.20944/preprints202005.0445.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
oral cancer; cancer-associated fibroblasts; metastasis; cell migration; cell invasion; Akt; EGFR
Online: 27 May 2020 (08:25:20 CEST)
REVIEW
|
doi:10.20944/preprints202406.0219.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
BLMH; BPHL; PON1; homocysteine thiolactone; PHF8; mTOR signaling; autophagy; Alzheimer’ s disease
Online: 5 June 2024 (07:32:32 CEST)
REVIEW
|
doi:10.20944/preprints202101.0120.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
mTOR; ATP; protein synthesis; autophagy; amino acids; nutrition; adipose tissue; muscle; sarcopenia; mitochondria
Online: 6 January 2021 (14:32:22 CET)
REVIEW
|
doi:10.20944/preprints202004.0060.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
COVID-19; coronavirus; cytokine storm; immunity; ADE; cross-reactive antibody; rapamycin; mTOR inhibotors
Online: 6 April 2020 (14:03:00 CEST)
REVIEW
|
doi:10.20944/preprints202310.1203.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
cancer; microRNA; AKT3; AKT signaling; small non-coding RNAs; circRNA; lncRNA; epigenetic regulation
Online: 19 October 2023 (05:08:12 CEST)
ARTICLE
|
doi:10.20944/preprints202306.0050.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
ASD; autism; autistic spectrum disease; NSE; Neuron-specific enolase; autism biomarker; neuroinflammation; neuronal apoptosis; mTOR
Online: 1 June 2023 (07:30:35 CEST)
REVIEW
|
doi:10.20944/preprints202108.0552.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
antagonistic pleiotropy; insulin/IGF-1 signalling; hyperfunction; quasi-programs; mTOR; theories of aging; programmatic aging
Online: 30 August 2021 (16:11:02 CEST)
COMMUNICATION
|
doi:10.20944/preprints202406.0680.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Inflammation, oxidative stress, apoptosis, STAT1, STAT3, IL-10, Heme Oxygenase-1, AKT, p38 and p53.
Online: 11 June 2024 (11:27:47 CEST)
REVIEW
|
doi:10.20944/preprints201809.0364.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
clear cell renal cell carcinoma; hypoxia inducible factors (HIFs); selenium; PD-L1; miRNA; VEGF; mTOR inhibitors
Online: 19 September 2018 (05:10:22 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1857.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
γH2AX; Actinomycin D; Akt; DNA damage response; DNA double-strand break; DNA-PK; Etoposide; p95/NBS1
Online: 26 May 2023 (05:11:01 CEST)
ARTICLE
|
doi:10.20944/preprints202106.0169.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
melanoma initiating cells; CD133; drug resistance; apoptosis; caspase activation; CRISPR-Cas9 knockout; AKT; BAD; BCL-2 family
Online: 7 June 2021 (12:11:10 CEST)
REVIEW
|
doi:10.20944/preprints202104.0379.v1
Subject:
Social Sciences,
Psychology
Keywords:
Substantia nigra; mTOR; SUMO E3 ligase; Huntington’s disease; 3,4-methylenedioxymethamphetamine (MDMA); autophagy; L-Dopa-induced dyskinesia (LID); mitophagy
Online: 14 April 2021 (13:41:05 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0796.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
anesthesia neurotoxicity; neuropathic pain; neural activity; mammalian target of rapamycin (mTOR); dorsal spinal cord (DSC), dorsal root ganglion (DRG).
Online: 10 August 2023 (08:17:30 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0820.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
Manuka honey, breast cancer, estrogen receptor positive breast cancer, triple negative breast cancer, in vivo xenografts, AMP Kinase signaling, mTOR, STAT3.
Online: 12 June 2024 (10:11:39 CEST)
REVIEW
|
doi:10.20944/preprints202309.0633.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
metastatic hormone-sensitive prostate cancer; new hormonal agents; transcriptomic profiling; DNA damage repair genes; tumor suppressor genes; androgen receptor; immunotherapy; CDK4/6 inhibitors; PARP inhibitors; AKT inhibitors.
Online: 11 September 2023 (07:17:07 CEST)