REVIEW
|
doi:10.20944/preprints202311.1051.v1
Subject:
Biology And Life Sciences,
Parasitology
Keywords:
Toxoplasma gondii; proteomics; host-parasite interactions; PTMs; drug discovery
Online: 16 November 2023 (07:46:09 CET)
ARTICLE
|
doi:10.20944/preprints202310.0918.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
drug sensitivity scores; molecular modeling; molecular docking; four-parameter logistic curve
Online: 16 October 2023 (11:38:46 CEST)
REVIEW
|
doi:10.20944/preprints202310.0962.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
oxygen; nanobubbles; hypoxia; mitochondria; metabolism, molecular; drug delivery; cancer, stress; innovation
Online: 16 October 2023 (11:09:22 CEST)
ARTICLE
|
doi:10.20944/preprints202309.1049.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
adverse drug reactions; anaphylactic reactions; arthralgia; hip synovitis; central precocious puberty
Online: 15 September 2023 (07:09:15 CEST)
ARTICLE
|
doi:10.20944/preprints202308.2158.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Ebola virus; measles virus; VP35; PKR; PACT; RIG-I; drug screen.
Online: 31 August 2023 (08:42:45 CEST)
ARTICLE
|
doi:10.20944/preprints202308.2094.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
biosimilars; bio-originators; biologic drug; ulcerative colitis; Crohn’s disease; interchangeability; economics
Online: 31 August 2023 (02:41:46 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0134.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
antimicrobial peptide; drug-resistant bacteria; cathelicidin; multifunction; aromatic and aliphatic residue
Online: 2 August 2023 (10:24:33 CEST)
ARTICLE
|
doi:10.20944/preprints202307.2088.v1
Subject:
Chemistry And Materials Science,
Physical Chemistry
Keywords:
non-steroidal anti-inflammatory drug; NSAID; lipid bilayer; EPR; 2H ESEEM
Online: 31 July 2023 (10:22:02 CEST)
ARTICLE
|
doi:10.20944/preprints202307.0343.v1
Subject:
Chemistry And Materials Science,
Polymers And Plastics
Keywords:
Favipiravir; pomegranate peels; chitosan; pectin; controlled drug release; gluteraldehyde; sodium hexametaphosphate
Online: 5 July 2023 (14:54:10 CEST)
ARTICLE
|
doi:10.20944/preprints202306.1076.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
Thymoquinone; SBE-β-CD; Leukemia; Drug delivery system; Telomerase inhibition; Apoptosis
Online: 15 June 2023 (05:37:50 CEST)
ARTICLE
|
doi:10.20944/preprints202306.0257.v1
Subject:
Medicine And Pharmacology,
Dermatology
Keywords:
wound dressing; drug delivery; organ culture, infection models, ciprofloxacin, infected wounds
Online: 5 June 2023 (08:09:29 CEST)
ARTICLE
|
doi:10.20944/preprints202306.0109.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
triple negative breast cancer; MCAK/KIF2C; aneuploidy; chromosomal instability; drug discovery
Online: 1 June 2023 (15:47:29 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1693.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
Digital twin; Clinical trials; Quality by Design; Blockchain technology; Drug development
Online: 24 May 2023 (04:46:13 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1006.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Melanoma; drug discovery; spliceosomal inhibition; BRAF; cell line xenograft; organ histopathology
Online: 15 May 2023 (09:19:54 CEST)
ARTICLE
|
doi:10.20944/preprints202305.0332.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
Ophthalmology; Toxicology Pharmacology and therapeutics; Drug interactions; Pharma-cology and therapeutics
Online: 5 May 2023 (08:56:37 CEST)
REVIEW
|
doi:10.20944/preprints202212.0581.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Japanese encephalitis (JE); Japanese Encephalitis Virus (JEV); Therapeutics; Vaccine; Antiviral; Drug
Online: 30 December 2022 (09:57:27 CET)
BRIEF REPORT
|
doi:10.20944/preprints202211.0063.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
melanoma; drug discovery; spliceosomal inhibition; acute toxicity; blood chemistry; organ histopathology
Online: 3 November 2022 (01:43:05 CET)
ARTICLE
|
doi:10.20944/preprints202210.0219.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Endometriosis; Orbignya speciosa; Copaifera lansgdorffii nanoemulsion; self-nanoemulsifying drug delivery system
Online: 17 October 2022 (02:07:50 CEST)
REVIEW
|
doi:10.20944/preprints202210.0148.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
drug development; high throughput screening; in vivo/in silico screening; zebrafish
Online: 11 October 2022 (10:33:33 CEST)
COMMUNICATION
|
doi:10.20944/preprints202208.0039.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Echovirus; enterovirus; broad-spectrum antiviral agent; antiviral drug combination; antiviral strategy
Online: 2 August 2022 (05:01:21 CEST)
REVIEW
|
doi:10.20944/preprints202206.0333.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
hPSCs derived-organoids; Culture strategy; Disease modeling; Drug screening; Regenerative therapy
Online: 24 June 2022 (08:11:15 CEST)
REVIEW
|
doi:10.20944/preprints202201.0117.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
G protein-coupled receptor; mouse models; skin cancer; UVR; drug; network
Online: 10 January 2022 (13:41:08 CET)
REVIEW
|
doi:10.20944/preprints202110.0069.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
biology; drug resistance; gene expression profiling; mRNA; multiple myeloma; prognosis; treatment
Online: 5 October 2021 (08:20:44 CEST)
ARTICLE
|
doi:10.20944/preprints202110.0021.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
chitosan; dexketoprofen trometamol; drug delivery; gelatin; NSAIDs; personalized medicine; smart polymers
Online: 1 October 2021 (13:53:53 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Otolaryngology
Keywords:
Drug-induced hearing loss; cochlea; outer hair cells; hearing protection; SIRT3
Online: 9 August 2021 (07:50:36 CEST)
ARTICLE
|
doi:10.20944/preprints202108.0031.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
antibiotics; antimicrobial resistance; antimicrobial stewardship; AWaRe; Pharmacovigilance; Lareb; adverse drug reactions
Online: 2 August 2021 (12:27:02 CEST)
ARTICLE
|
doi:10.20944/preprints202107.0246.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
influenza virus; virus-host interaction; commonly prescribed drugs; drug adverse reaction
Online: 12 July 2021 (11:37:07 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0308.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Indonesia; biodiversity; novel antibiotics; drug screening; bioactivity; gene cluster networking; GNPS
Online: 13 May 2021 (14:05:00 CEST)
ARTICLE
|
doi:10.20944/preprints202012.0534.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
creatinine; vancomycin; amikacin; renal impairment; acute kidney injury; adverse drug reaction
Online: 21 December 2020 (15:42:59 CET)
ARTICLE
|
doi:10.20944/preprints202011.0610.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Artesunate; Drug resistance; Malaria; Quinine; Rapid diagnostic test; Plasmodium falciparum; Sahel
Online: 24 November 2020 (09:51:45 CET)
ARTICLE
|
doi:10.20944/preprints202009.0205.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Franz-Bampa; BCS drugs; biomimetic membrane; Franz cell; passive drug transport
Online: 9 September 2020 (10:25:54 CEST)
REVIEW
|
doi:10.20944/preprints202008.0729.v2
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
p53; p73; MDM2; MDMX; tumor suppressor; drug repurposing; aspirin; protoporphyrin IX; verteporfin
Online: 17 September 2020 (07:23:37 CEST)
REVIEW
|
doi:10.20944/preprints202007.0478.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Bioinformatics; Drug Design; Small Organic Molecule; Target identification; Web-based Server
Online: 25 July 2020 (17:50:30 CEST)
ARTICLE
|
doi:10.20944/preprints202006.0358.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Enzyme inhibition; Secondary Metabolites; In-silico Analysis; Molecular docking; Drug candidates
Online: 30 June 2020 (08:11:28 CEST)
CONCEPT PAPER
|
doi:10.20944/preprints202004.0213.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
covid-19; rlmE MTase; new drug target; corona diagnosis; corona pandemic
Online: 13 April 2020 (12:33:22 CEST)
REVIEW
|
doi:10.20944/preprints202004.0012.v1
Subject:
Chemistry And Materials Science,
Theoretical Chemistry
Keywords:
chemoinformatics; chemical space; database; LANaPD; molecular diversity; drug discovery; natural sources
Online: 2 April 2020 (04:47:13 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
humans; infection control; therapy; coronavirus; immunoglobulins; drug therapy; therapeutic use; corticosteroid
Online: 8 March 2020 (17:04:19 CET)
ARTICLE
|
doi:10.20944/preprints201911.0104.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
chemical synthesis; IC50; ED50; CC50; antimalarial resistance; sarcosine-aniline hybrid drug
Online: 10 November 2019 (10:10:15 CET)
REVIEW
Subject:
Medicine And Pharmacology,
Anesthesiology And Pain Medicine
Keywords:
pharmacology; drug development; sodium channel; potassium channel; TRP channel; HCN channels
Online: 8 August 2019 (12:31:26 CEST)
ARTICLE
|
doi:10.20944/preprints201901.0250.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
drug delivery system, muscle atrophy, nanoparticle, prostaglandin E1, sciatic nerve injury
Online: 24 January 2019 (08:51:02 CET)
ARTICLE
|
doi:10.20944/preprints201810.0236.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
essential oils; drug resistant microorganisms; antimicrobial activity; antifungal activity; medicinal plants
Online: 11 October 2018 (11:51:16 CEST)
HYPOTHESIS
|
doi:10.20944/preprints201808.0127.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Big Data, Systems Models, Cancer metabolism, Cancer personalized treatment, Drug Discovery.
Online: 6 August 2018 (15:09:15 CEST)
ARTICLE
|
doi:10.20944/preprints201806.0192.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
β4-galactosyltransferase 4; transcriptional mechanism; sensor cells; colon cancer; drug screening
Online: 12 June 2018 (12:51:07 CEST)
REVIEW
|
doi:10.20944/preprints201805.0378.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
annexins; inflammation; wound healing; host-pathogen interplay; drug target; translational research
Online: 27 May 2018 (11:32:34 CEST)
ARTICLE
|
doi:10.20944/preprints201804.0310.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
primary open angle glaucoma; dorzolamide/timolol fixed combination; drug efficacy; safety
Online: 24 April 2018 (08:36:58 CEST)
REVIEW
|
doi:10.20944/preprints202402.1123.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Mycobacterium tuberculosis; multidrug-resistant; extensively drug-resistant; diagnostic methods; point-of-care; phenotypic methods; molecular methods; drug resistance detection; rapid test
Online: 20 February 2024 (11:46:19 CET)
COMMUNICATION
|
doi:10.20944/preprints202007.0709.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
intrinsic multi-drug resistance; acquired multi-drug resistance; circulating tumor cells; single cells; cell clusters; cell monolayer; multi-cellular spheroids; cytometry of reaction rate constant; ovarian cancer
Online: 30 July 2020 (09:01:50 CEST)
ARTICLE
|
doi:10.20944/preprints202408.1941.v1
Subject:
Computer Science And Mathematics,
Mathematical And Computational Biology
Keywords:
Drug Response Prediction; Graph Neural Network; Graph Attention Networks; Heterogeneous Graph; Interpretability
Online: 27 August 2024 (12:44:15 CEST)
ARTICLE
|
doi:10.20944/preprints202407.2353.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
cell membrane-derived liposomes; Memposomes; drug delivery vehicle; homologous targeting; E-cadherin
Online: 30 July 2024 (07:45:23 CEST)
REVIEW
|
doi:10.20944/preprints202407.1682.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
pharmacogenetics; blood-brain barrier; drug discovery; personalised medicine; precision medicine; clinical translation
Online: 22 July 2024 (09:54:15 CEST)
ARTICLE
|
doi:10.20944/preprints202407.1667.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
active targeting; CRT peptide; drug delivery; cancer; nanoemulsion
Online: 22 July 2024 (07:50:13 CEST)
ARTICLE
|
doi:10.20944/preprints202406.1032.v1
Subject:
Medicine And Pharmacology,
Endocrinology And Metabolism
Keywords:
Semaglutide Analogues; GLP-1 Receptor Agonists; Binding Affinity Optimization; Computational Drug Design;
Online: 17 June 2024 (09:12:54 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0976.v1
Subject:
Medicine And Pharmacology,
Orthopedics And Sports Medicine
Keywords:
polylactide– polyglycolide; vancomycin; lithium; drug delivery; WNT agonist; mesenchymal stem cells
Online: 14 June 2024 (09:37:05 CEST)
CONCEPT PAPER
|
doi:10.20944/preprints202405.1739.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
Drug Discovery & Design; Synthetic Data Generation; Intermolecular Binding Affinity (Kd); GIBAC
Online: 27 May 2024 (10:49:40 CEST)
REVIEW
|
doi:10.20944/preprints202404.1013.v3
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
computational pharmaceutics; AI; multi-scale modeling; quantum computing; drug discovery; blockchain frameworks
Online: 22 April 2024 (18:38:54 CEST)
ARTICLE
|
doi:10.20944/preprints202404.1198.v1
Subject:
Environmental And Earth Sciences,
Oceanography
Keywords:
multi-drug resistant bacteria; microbial treatment; coastal organic waste; Pseudomonadale; marine microorganisms
Online: 18 April 2024 (08:10:05 CEST)
REVIEW
|
doi:10.20944/preprints202404.0674.v1
Subject:
Environmental And Earth Sciences,
Other
Keywords:
Microneedles; Bioactive molecules; Transdermal drug delivery system; Design parameters; Manufacturing techniques; Usage
Online: 9 April 2024 (14:52:30 CEST)
ARTICLE
|
doi:10.20944/preprints202403.1775.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Hepatitis B virus; Antivirals; Flavonoid; Drug discovery; Pharmacophore; Quantitative structure-activity relationship
Online: 28 March 2024 (13:31:24 CET)
REVIEW
|
doi:10.20944/preprints202403.0140.v1
Subject:
Medicine And Pharmacology,
Complementary And Alternative Medicine
Keywords:
Cancer Pharmacotherapy; Drug development; Kinesin motor proteins; Microtubules; Mitotic kinases; Mitotic poisons
Online: 4 March 2024 (11:17:25 CET)
REVIEW
|
doi:10.20944/preprints202402.0148.v1
Subject:
Medicine And Pharmacology,
Dentistry And Oral Surgery
Keywords:
medication-related osteonecrosis of the jaw; drug holiday; treatment; tooth extraction; incidence
Online: 2 February 2024 (11:48:46 CET)
REVIEW
|
doi:10.20944/preprints202312.2253.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Ganoderma lucidum; Nanotechnology; Nanoparticles; Triterpenoids; Polysaccharides; Bioactive compounds; Drug delivery; Cancer therapy
Online: 29 December 2023 (11:31:12 CET)
ARTICLE
|
doi:10.20944/preprints202311.1816.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
essential antimicrobials; essential medicine list; drug procurement; gap analysis; paediatric antibiotic formulations
Online: 29 November 2023 (11:04:15 CET)
ARTICLE
|
doi:10.20944/preprints202311.0653.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Cytochrome P450 oxidoreductase; POR; gnomAD, CAH; drug metabolism, steroid hormones; SNV; bioinformatics
Online: 9 November 2023 (15:09:12 CET)
ARTICLE
|
doi:10.20944/preprints202310.0396.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Pyrimidine; Homology Modelling; Pharmacophore Mapping; 3D-QSAR; Molecular Docking; ADMET; Drug Design
Online: 9 October 2023 (09:36:05 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0467.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
pan-cancer analysis; RKIP; YY1; gene expression; mutations; immune infiltration; drug resistance
Online: 7 September 2023 (13:33:14 CEST)
ARTICLE
|
doi:10.20944/preprints202308.2113.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
herbs; spices; flavonoids; antioxidants; diabetes; volatile compounds; drug discovery; phytochemicals; human health
Online: 31 August 2023 (10:12:18 CEST)
ARTICLE
|
doi:10.20944/preprints202307.1577.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
deep learning, transformer, drug use detection, exploratory data analysis, natural language processing.
Online: 24 July 2023 (10:57:47 CEST)
ARTICLE
|
doi:10.20944/preprints202306.0038.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
Lagenaria siceraria; In silico study; Drug design; Diabetes mellitus; Molecular docking; ADMET
Online: 1 June 2023 (05:41:13 CEST)
REVIEW
|
doi:10.20944/preprints202305.1084.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
antibody-drug conjugate; lysosome; cathepsin; legumain; self-immolation; payload release; peptidomimetic; linker
Online: 16 May 2023 (04:51:34 CEST)
REVIEW
|
doi:10.20944/preprints202212.0207.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Blood-Brain Barrier; Brain Drug Delivery; Carbon Nanomaterials; Cerebral Gliomas; Glioblastoma; Nanoparticles.
Online: 12 December 2022 (14:56:45 CET)
ARTICLE
|
doi:10.20944/preprints202211.0296.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
antimicrobial resistance; broad-spectrum antibiotics; antibacterial drug discovery; gram-negative bacteria; pyrrolobenzodiazepines
Online: 16 November 2022 (04:20:55 CET)
ARTICLE
|
doi:10.20944/preprints202208.0207.v3
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
Adverse Drug Reaction; Spontaneous reporting; Active surveillance; Underreporting; Antiglau-coma; Artificial tear
Online: 11 October 2022 (03:18:55 CEST)
REVIEW
|
doi:10.20944/preprints202208.0230.v1
Subject:
Chemistry And Materials Science,
Theoretical Chemistry
Keywords:
chemoinformatics; compound databases; chemical space; diversity; drug discovery; openscience; pseudo-natural product
Online: 12 August 2022 (08:39:40 CEST)
ARTICLE
|
doi:10.20944/preprints202206.0183.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
Biomarkers; Drug Signature Identification; Key pathways; Oral Cancer; Oral Squamous Cell Carcinoma
Online: 13 June 2022 (10:14:58 CEST)
ARTICLE
|
doi:10.20944/preprints202111.0072.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
antimalarial drugs; artemisinins; ACTs; resistance; amino-artemisinins, pharmacokinetics; metabolism; Cmax; drug efficacy
Online: 3 November 2021 (09:10:50 CET)
ARTICLE
|
doi:10.20944/preprints202106.0279.v1
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
Blood-Brain Barrier, Penetrating Peptides, Machine learning techniques, Drug delivery, Therapeutic peptides
Online: 10 June 2021 (08:13:15 CEST)
REVIEW
|
doi:10.20944/preprints202104.0652.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
Enzymatic reaction; crosslinking; Hydrogel; Biomedical application; Tissue engineering; Wound healing; Drug delivery
Online: 26 April 2021 (10:52:24 CEST)
ARTICLE
|
doi:10.20944/preprints202103.0621.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Auger electron; cisplatin; 191Pt; 189Pt; radio-drug; DNA double-strand break; γH2AX
Online: 25 March 2021 (14:30:14 CET)
CASE REPORT
|
doi:10.20944/preprints202103.0054.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
DRESS syndrome, Eosinophilia, Adverse drug reaction, HHV-6 reactivation, Bactrim adverse reaction
Online: 2 March 2021 (09:26:48 CET)
REVIEW
|
doi:10.20944/preprints202102.0449.v1
Subject:
Chemistry And Materials Science,
Materials Science And Technology
Keywords:
multifunctional; hydrogel nanocomposties; tissue engineering; drug delivery; wound healing; bioprinting; biowearable devices
Online: 22 February 2021 (08:48:20 CET)
REVIEW
|
doi:10.20944/preprints202012.0242.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
COVID-19; SARS-CoV-2; long-haul; inflammation; tissue damage; drug repurposing
Online: 10 December 2020 (09:42:20 CET)
COMMUNICATION
|
doi:10.20944/preprints202011.0441.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Sars-Cov-2; Proteomic,; Ghost proteome,; Alternative proteins,; AltOrf.; interactomic; drug repurposing
Online: 16 November 2020 (17:50:19 CET)
ARTICLE
|
doi:10.20944/preprints202004.0524.v2
Subject:
Biology And Life Sciences,
Virology
Keywords:
unsupervised learning; tensor decomposition; feature selection; COVID-19; drug discovery; gene expression
Online: 3 June 2020 (05:29:09 CEST)
ARTICLE
|
doi:10.20944/preprints202004.0448.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
acetyleugenol; Acacia nilotica; anti-tuberculosis; Serine/Threonine kinases; multi-drug resistant TB
Online: 24 April 2020 (14:12:33 CEST)
ARTICLE
|
doi:10.20944/preprints202003.0413.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
coronavirus; drug; COVID-19; SARS; MERS; ontology; ChEBI; NDF-RT; DrON; bioinformatics
Online: 29 March 2020 (01:58:40 CET)
ARTICLE
|
doi:10.20944/preprints202003.0393.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
SARS-CoV2; RNA depended RNA polymerase; Valproic acid Co-A; drug repurposing
Online: 26 March 2020 (15:04:22 CET)
ARTICLE
|
doi:10.20944/preprints202002.0178.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
DILIrank; DILI; drug hepatotoxicity; QSAR; nested cross-validation; virtual screening; in silico
Online: 14 February 2020 (02:24:04 CET)
REVIEW
|
doi:10.20944/preprints201906.0002.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
patient-derived xenograft; immunocompromised mice; precision medicine; drug screening; cancer; cell line
Online: 3 June 2019 (04:47:14 CEST)
ARTICLE
|
doi:10.20944/preprints201810.0381.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Biginelli reaction; dihydropyrimidin-2-thiones; synthesis, virtual screening, drug design; LaSOM 282
Online: 17 October 2018 (09:34:06 CEST)
REVIEW
|
doi:10.20944/preprints201801.0218.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Biocompatibility; Biodegradability; Biopolyesters; Biopolymers; Composites; Drug Release; Implants; Polyhydroxyalkanoates; Scaffolds; Tissue Engineering
Online: 23 January 2018 (16:49:05 CET)
ARTICLE
|
doi:10.20944/preprints201712.0024.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
HIV-1; quasispecies; minority resistance mutations; HAART; drug resistance; undetectable viral load
Online: 4 December 2017 (09:34:16 CET)
REVIEW
|
doi:10.20944/preprints202408.1827.v1
Subject:
Computer Science And Mathematics,
Mathematical And Computational Biology
Keywords:
Predictive Toxicology; Omics Technologies; Machine Learning; Structure-Activity Relationship; Fragment-Based Drug Design; Microphysiological Systems; Physiologically Based Pharmacokinetic Modeling; Virtual Screening; Biochemical Targets; Automated De Novo Drug Design
Online: 26 August 2024 (11:31:51 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0480.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
camptothecin; drug distribution; drug-membrane interaction; biophysical profiling; biomimetic models; partition coefficient; ADMET/PK prediction; small and wide-angle X-ray diffraction; fluorescence spectroscopy; human serum albumin (HSA)
Online: 20 May 2021 (10:52:33 CEST)
REVIEW
|
doi:10.20944/preprints202408.0229.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Alzheimer's disease; mesenchymal stem cells; Drug discovery and development; Neurosurgery; Neurology; Novel theapies
Online: 6 August 2024 (05:20:17 CEST)
REVIEW
|
doi:10.20944/preprints202407.2544.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
antioxidants; liver cancer; nano-formulations; drug delivery; natural compounds; hepatocellular carcinoma; oxidative stress
Online: 31 July 2024 (14:02:17 CEST)
ARTICLE
|
doi:10.20944/preprints202407.1733.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
Berberine hydrochloride; Chitosan/Carboxymethyl-β-Cyclodextrin; Hydrogel formulation; Solubility enhancement; Oral drug delivery.
Online: 22 July 2024 (17:36:55 CEST)
ARTICLE
|
doi:10.20944/preprints202407.1116.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Hepatitis C virus; MD Simulations; Covalent inhibitor; Drug resistance; Pharmacophore-based virtual screening
Online: 16 July 2024 (04:54:08 CEST)
COMMUNICATION
|
doi:10.20944/preprints202407.0769.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
Oritavancin; prosthetic joint infections; PJI; therapeutic drug monitoring; TDM; MR; suppressive therapy; outpatient
Online: 10 July 2024 (11:59:23 CEST)
ARTICLE
|
doi:10.20944/preprints202407.0129.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
Atypical antipsychotics (AAPs), secondary drug effects, schizophrenia, liver, mitochondria, oxidative stress (OS), MAPK.
Online: 2 July 2024 (13:23:11 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0953.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
GIBAC; Intermolecular binding affinity (Kd); Structural biophysics; Synthetic data; Drug discovery \& design;
Online: 14 June 2024 (05:04:28 CEST)