ARTICLE
|
doi:10.20944/preprints202304.1195.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
COVID-19 pandemic; antimicrobial resistance; infectious diseases consultation; multi-drug resistant bacteria; infection prevention and control group; antibiotic stewardship
Online: 29 April 2023 (03:23:00 CEST)
ARTICLE
|
doi:10.20944/preprints201905.0109.v2
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
child; diarrhea; water sanitation and hygiene; rehydration solution; zinc; case management; antibacterial agents; drug utilization; community participation; India
Online: 14 May 2019 (11:46:53 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0953.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
GIBAC; Intermolecular binding affinity (Kd); Structural biophysics; Synthetic data; Drug discovery \& design;
Online: 14 June 2024 (05:04:28 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0085.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
precision medicine; drug response prediction; cell-free mRNA; transcriptomic profiling; gene expression signature
Online: 6 June 2024 (03:09:40 CEST)
ARTICLE
|
doi:10.20944/preprints202312.2280.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Free-floating organoids; non-small cell lung cancer; cytokine; drug resistance; personalized medicine
Online: 29 December 2023 (13:28:30 CET)
ARTICLE
|
doi:10.20944/preprints202312.2016.v2
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
interpolyelectrolyte complexes; Eudragit® ; gastroretentive systems; drug delivery systems; bioadhesive systems; metronidazole; acyclovir
Online: 27 December 2023 (14:28:59 CET)
ARTICLE
|
doi:10.20944/preprints202311.1460.v1
Subject:
Biology And Life Sciences,
Parasitology
Keywords:
Onchocerciasis; drug discovery; anthelmintics; O. gutturosa; motility and MTT inhibition; FDA approved drugs
Online: 23 November 2023 (09:31:11 CET)
REVIEW
|
doi:10.20944/preprints202310.0771.v1
Subject:
Medicine And Pharmacology,
Psychiatry And Mental Health
Keywords:
Alzheimer's disease; neural networks; Training and learning; early diagnosis; drug discovery; brain diseases
Online: 12 October 2023 (04:19:37 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1966.v1
Subject:
Chemistry And Materials Science,
Theoretical Chemistry
Keywords:
Drug discovery; computational chemistry; conceptual DFT; marine cyclopeptides; chemical reactivity properties; bioavailability scores
Online: 29 August 2023 (09:36:49 CEST)
ARTICLE
|
doi:10.20944/preprints202306.1793.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
bioactive compounds; black sea cucumbers; cancer; drug-target interactions; machine learning; molecular docking
Online: 26 June 2023 (10:36:43 CEST)
ARTICLE
|
doi:10.20944/preprints202304.0800.v1
Subject:
Biology And Life Sciences,
Toxicology
Keywords:
Brushtail possum; Trichosurus vulpecula; fertility control; and drug-metabolising enzymes (CYP3A and UGT2B)
Online: 23 April 2023 (13:11:28 CEST)
SHORT NOTE
|
doi:10.20944/preprints202212.0230.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
monoamine oxidase; inhibitors; indole; 1,2,4-oxadiazole; drug research; neuroprotective drugs; Parkinson’s disease; MAO
Online: 13 December 2022 (07:12:01 CET)
ARTICLE
|
doi:10.20944/preprints202210.0302.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
poxviruses; monkeypox virus; envelope proteins; drug repurposing; bioactive phytochemicals; molecular docking, molecular simulation
Online: 20 October 2022 (09:32:02 CEST)
ARTICLE
|
doi:10.20944/preprints202112.0203.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
enterovirus; antidepressant sertraline; drug repurposing; viral entry; host-cell targets; broad-spectrum antiviral
Online: 13 December 2021 (12:55:13 CET)
ARTICLE
|
doi:10.20944/preprints202104.0483.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
Network embedding; multiplex-heterogeneous network; multi-layer network; drug repositioning; graph representation learning
Online: 19 April 2021 (13:21:02 CEST)
REVIEW
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
hyperoxaluria; oxalate; inhibitor; small molecule drug; glycolate oxidase; lactate dehydrogenase; liver selective distribution
Online: 31 December 2020 (08:59:47 CET)
ARTICLE
|
doi:10.20944/preprints202012.0588.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Trazodone; drug design; dissolution; crystal structure; solid-state NMR (SSNMR) spectroscopy; GIPAW calculation
Online: 23 December 2020 (13:42:36 CET)
ARTICLE
|
doi:10.20944/preprints202011.0748.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Keywords: Brimonidine; Laponite; drug delivery; glaucoma; nanomedicine; monitoring; optical coherence tomography; vitreous; intravitreal.
Online: 30 November 2020 (20:25:24 CET)
ARTICLE
|
doi:10.20944/preprints202011.0512.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
antimicrobials; meropenem; generic drug; real-life studies; product surveillance, postmarketing; treatment outcome; pharmacovigilance
Online: 19 November 2020 (13:34:26 CET)
ARTICLE
|
doi:10.20944/preprints202010.0032.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
Nanomedicine; human ferritin; gastrointestinal tumors; non-camptothecin topoisomerase I inhibitors; drug-delivery; CD71
Online: 2 October 2020 (09:21:53 CEST)
REVIEW
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
apoptosis; antitumor; antimetastasis; anti-angiogenesis; NK-1 receptor; substance P; drug repositioning; Emend
Online: 31 August 2020 (10:11:13 CEST)
ARTICLE
|
doi:10.20944/preprints202007.0424.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
4-Phenylbutyric acid; Colon-targeted drug delivery; Colitis; Prodrug; ER stress; Chemical chaperone
Online: 19 July 2020 (19:15:20 CEST)
REVIEW
|
doi:10.20944/preprints201912.0179.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
globular set; category theory; multidimensional; visual recognition; drug-resistant epilepsy; transcranial magnetic stimulation.
Online: 13 December 2019 (10:37:03 CET)
ARTICLE
|
doi:10.20944/preprints201911.0024.v1
Subject:
Computer Science And Mathematics,
Information Systems
Keywords:
Iranian traditional medicine; Persian medicine; ontology; knowledge-base; Mizaj; temperament; new drug discovery
Online: 3 November 2019 (17:07:50 CET)
ARTICLE
|
doi:10.20944/preprints201908.0253.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
halogen bonding; fluorine; iodine; pentafluorosulfanyl; titration; ab initio calculation; NMR study; drug design
Online: 25 August 2019 (15:41:59 CEST)
ARTICLE
|
doi:10.20944/preprints201803.0144.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
sea anemone; drug discovery; cancer; antiangiogenic; endothelial cells; RGD motif; Kunitz type inhibitor
Online: 19 March 2018 (08:15:38 CET)
ARTICLE
|
doi:10.20944/preprints201905.0370.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Targeted drug delivery, VX2 tumor, breast cancer, cryoablation, cryo-assisted injection, cryo-assisted resection, blue dye, epirubicin.
Online: 30 May 2019 (13:44:41 CEST)
ARTICLE
|
doi:10.20944/preprints202310.1395.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
Mpox infection; mpox vaccination; risk awareness, vaccine acceptance; vaccine hesitancy; health-related quality of life; the Short-Form 36-item questionnaire
Online: 24 October 2023 (07:56:10 CEST)
ARTICLE
|
doi:10.20944/preprints202007.0209.v1
Subject:
Engineering,
Control And Systems Engineering
Keywords:
Deep learning; Head Related Transfer Function (HRTF); Restoration; Ambisonics; Spatial Audio; Spherical harmonic; Audio signal processing; Denoising; Auto-Encoder; Neural Network
Online: 10 July 2020 (08:58:11 CEST)
ARTICLE
|
doi:10.20944/preprints202312.1519.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Durysta, Bimatoprost; Ciliary Sulcus, Middle Space Operations; MiSO; Middle Space Therapeutics; MiST; ArcScan; Ultrasound; Depot; Drug Delivery; Posterior Chamber; Sulcus
Online: 20 December 2023 (09:09:38 CET)
REVIEW
|
doi:10.20944/preprints202312.0387.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
big data; not-so-big data; molecular design; drug design; machine learning; artificial intelligence; descriptor; computer-generated descriptors; property; regression
Online: 6 December 2023 (10:19:02 CET)
ARTICLE
|
doi:10.20944/preprints202008.0316.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
nanoparticles; FA-DABA-SMA; drug delivery systems; folic acid receptor alpha; intracellular disruptions; invasion and migration; breast cancer
Online: 14 August 2020 (09:49:17 CEST)
ARTICLE
|
doi:10.20944/preprints202002.0003.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
drug repositioning/repurposing; dopamine transporter (DAT); benztropine; tumoroids; signal transducer and activator of transcription (STAT); circulating tumor cells (CTC); three-dimensional (3D) culture
Online: 3 February 2020 (03:16:54 CET)
ARTICLE
|
doi:10.20944/preprints202305.1605.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
pH sensitive Polymer; Methacrylate Polymers; Eudragit L100; Polymeric nanoparticles; Apocynin; Rheumatoid arthritis; Carbopol-934 based Hydrogel; Transdermal Drug Delivery System
Online: 23 May 2023 (07:51:12 CEST)
ARTICLE
|
doi:10.20944/preprints202408.0458.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
MRI visualization; combination therapy; multi-drug delivery platform; magnetotactic bacterial; enhanced photothermal-chemodynamic therapy
Online: 8 August 2024 (04:27:55 CEST)
ARTICLE
|
doi:10.20944/preprints202407.1735.v1
Subject:
Computer Science And Mathematics,
Probability And Statistics
Keywords:
drug safety; association rule mining; Apriori; safety data; disproportionality measures; pharmacovigilance; co-occurrence analysis
Online: 22 July 2024 (17:35:47 CEST)
ARTICLE
|
doi:10.20944/preprints202404.0199.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
follicular thyroid neoplasia; PAX8– PPARγ fusion; fusion protein; structure-based drug design
Online: 3 April 2024 (07:24:16 CEST)
ARTICLE
|
doi:10.20944/preprints202401.0661.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Protozoan diseases; Drug repurposing; Cytotoxicity; Dihydrofolate reductase inhibitors; Potassium (K+) channel blocker; ADME properties
Online: 9 January 2024 (10:30:36 CET)
ARTICLE
|
doi:10.20944/preprints202311.1667.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
α-MSH; melanoma; peptide-drug conjugates; in vitro antiproliferative effect; in vivo antitumor activity
Online: 27 November 2023 (08:49:52 CET)
COMMUNICATION
|
doi:10.20944/preprints202311.1268.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
SARS-CoV-2; COVID-19; RdRp; m1A triphosphate; Antiviral Drug
Online: 21 November 2023 (07:19:23 CET)
ARTICLE
|
doi:10.20944/preprints202309.1917.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Mycobacterium; Antibiotic resistance; Drug re-purposing; MbtA; Siderophores; Molecular Docking; Molecular Dynamics; PCA analysis
Online: 28 September 2023 (13:28:39 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0011.v1
Subject:
Medicine And Pharmacology,
Anesthesiology And Pain Medicine
Keywords:
immunoassay; urine drug test; opioid; nonmedical; cancer pain; safety-net hospital; palliative medicine; education
Online: 1 September 2023 (04:02:26 CEST)
REVIEW
|
doi:10.20944/preprints202308.0109.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
preclinical; oncology; 3D culture; organ-on-a-chip; spheroid; organoid; 3D bioprinting; drug screening
Online: 2 August 2023 (02:48:00 CEST)
ARTICLE
|
doi:10.20944/preprints202112.0446.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
sleep breathing disorders; mandibular advancement; MAD; titratable positioner; drug-induced sleep endoscopy; patient selection.
Online: 28 December 2021 (11:03:45 CET)
ARTICLE
|
doi:10.20944/preprints202108.0512.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
oyster mushroom (Pleurotus sp.); PARP protein; 4UND protein; molecular docking; PyRx; BIOVIA drug discovery
Online: 26 August 2021 (16:15:06 CEST)
ARTICLE
|
doi:10.20944/preprints202011.0307.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
TiO2 nanoparticles; antibacterial activity; multi-drug-resistance pathogens; MRSA; E. coli. P. aeruginosa; genotoxicity
Online: 10 November 2020 (12:09:17 CET)
ARTICLE
|
doi:10.20944/preprints202004.0369.v2
Subject:
Biology And Life Sciences,
Virology
Keywords:
COVID-19; SARS-CoV-2; spike protein; ACE1; ACE2; host-virus interaction; drug repurposing
Online: 2 August 2020 (09:23:18 CEST)
REVIEW
|
doi:10.20944/preprints201908.0271.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
GPCRs; membrane protein; molecular dynamics; protein structure; drug design; biased-signaling pathway; allosteric sites
Online: 26 August 2019 (15:34:57 CEST)
ARTICLE
|
doi:10.20944/preprints201811.0627.v1
Subject:
Chemistry And Materials Science,
Theoretical Chemistry
Keywords:
chemical space; chemical data set; chemoinformatics; consensus diversity plot; drug discovery; molecular diversity; visualization
Online: 30 November 2018 (10:06:15 CET)
ARTICLE
|
doi:10.20944/preprints201804.0374.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
STAT3 as a drug target; cyclic STAT3 decoy; oligodeoxynucleotide inhibitor; head and neck cancer
Online: 29 April 2018 (10:10:00 CEST)
ARTICLE
|
doi:10.20944/preprints201801.0136.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
polymer-drug association; inclusion nano-complex; an amphiphilic polymer; polysoaps; antibiotic resistance; ampicillin trihydrate
Online: 16 January 2018 (07:56:15 CET)
REVIEW
|
doi:10.20944/preprints201709.0050.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Alzheimer's-disease; dementia; drug targeting; nanoemulsion; neuroinflammation; oxidative stress; scavenger receptors; sonoporation; transcranial ultrasound
Online: 13 September 2017 (05:44:29 CEST)
REVIEW
|
doi:10.20944/preprints202007.0016.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
myeloma; BCMA; bispecific T-cell engager; antibody-drug conjugates; chimeric antigen receptor T-cells; belantamab mafodotin; idecabtagene vicleucel; JNJ-68284528
Online: 3 July 2020 (07:30:57 CEST)
REVIEW
|
doi:10.20944/preprints202310.0180.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
Age-related macular degeneration; confocal scanning laser ophthalmoscope; fundus autofluorescence; macular atrophy; microperimetry; multifocal electroretinogram; optical coherence tomography angiography; optical coherence tomography
Online: 4 October 2023 (07:41:14 CEST)
ARTICLE
|
doi:10.20944/preprints202012.0252.v1
Subject:
Social Sciences,
Psychology
Keywords:
Fear extinction; Fear Conditioning; Medial Prefrontal Cortex; RNA sequencing; Differential Gene Expression; Electrophysiological Recordings; Excitatory Post-Synaptic Currents; Spinogenesis; Fear-related Disorders
Online: 10 December 2020 (11:38:50 CET)
ARTICLE
|
doi:10.20944/preprints202305.0650.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
3D printing; hybrid scaffold; poly(caprolactone); chitosan; vancomycin; mesenchymal stem cells; tissue engineering; drug-delivery systems (DDSs); M osteomyelitis
Online: 9 May 2023 (12:05:37 CEST)
REVIEW
|
doi:10.20944/preprints202308.1518.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
SARS-CoV-2; main protease; inhibitors; molecular modeling; molecular dynamics simulations; binding energy calculation; ADME properties; potential therapeutics; drug discovery
Online: 22 August 2023 (07:19:37 CEST)
ARTICLE
|
doi:10.20944/preprints201707.0033.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
hepatic inflammation; high-fat-cholesterol diet; hypertension; mitogen-activated protein kinase; nonalcoholic steatohepatitis; nuclear factor erythroid 2-related factor 2 pathway; nuclear factor-kappa B; spontaneously hypertensive rat; stroke-prone spontaneously hypertensive5/Dmcr; Wistar Kyoto
Online: 14 July 2017 (10:54:38 CEST)
REVIEW
|
doi:10.20944/preprints202205.0037.v1
Subject:
Medicine And Pharmacology,
Dermatology
Keywords:
Melanoma; Chemo-thermo-immuno-therapy; Melanogenesis; Magnetite nanoparticle; Drug delivery system; Heat shock protein; In situ vaccine therapy; Immune checkpoint inhibitor
Online: 5 May 2022 (12:23:27 CEST)
REVIEW
|
doi:10.20944/preprints202312.0424.v1
Subject:
Chemistry And Materials Science,
Materials Science And Technology
Keywords:
nanoparticles; PLGA; Electrospinning; 3D printing; Techniques; bone regeneration, biomaterial, biocompatibility, biodegradability, bioactive molecules, drug delivery
Online: 7 December 2023 (01:35:39 CET)
ARTICLE
|
doi:10.20944/preprints202310.0546.v2
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
Candida auris; C. auris; Candida; Candidemia; Multi-drug resistant organism; MDRO; Emerging pathogens; Resistant pathogens
Online: 30 November 2023 (12:04:07 CET)
ARTICLE
|
doi:10.20944/preprints202308.1427.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
pulmonary tuberculosis, Mycobacterium tuberculosis, alveolar macrophages, drug tolerance, persistence, dormancy, biomarkers, non-acid-fastness, Rv2623
Online: 21 August 2023 (12:11:01 CEST)
ARTICLE
|
doi:10.20944/preprints202306.1494.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
microgravity; chemotherapy; paclitaxel; hydroxyurea; morphometry; drug response; immune dysfunction; space medicine; terrestrial medicine; fluorescence microscopy
Online: 21 June 2023 (07:34:49 CEST)
REVIEW
|
doi:10.20944/preprints202306.1176.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
lung cancer; organoid; drug screening; high throughput; translational; pre-clinical; clinical; tumor microenvironment; personalized medicine
Online: 16 June 2023 (08:42:28 CEST)
ARTICLE
|
doi:10.20944/preprints202304.0914.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Metformin; Quorum sensing; Quorum quenching; Pseudomonas aeruginosa; Virulence; Drug repurposing; Anti-virulence therapy; Biofilm inhibition
Online: 25 April 2023 (09:54:20 CEST)
ARTICLE
|
doi:10.20944/preprints202111.0125.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
artificial intelligence; de novo design; fragment-based drug discovery; HIV-1 inhibitors; pseudo natural products
Online: 8 November 2021 (09:23:49 CET)
REVIEW
|
doi:10.20944/preprints202109.0491.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Tuberculosis; Mycobacterium; Diagnostics; Drug Discovery; Antibiotics; Antimicrobial Re-sistance; Microfluidics; Single-Cell Analysis; Bioengineered Models
Online: 29 September 2021 (11:34:04 CEST)
REVIEW
|
doi:10.20944/preprints202109.0432.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Non-genetic heterogeneity; multistability; drug-tolerant persisters; phenotypic plasticity; biological noise; epithelial-mesenchymal plasticity; PAGE4
Online: 24 September 2021 (12:44:34 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
gas chromatography mass spectrometry; metabolomics; acute lymphoblastic leukemia; confocal microscopy; high-throughput drug screens; VAST
Online: 7 June 2021 (08:01:21 CEST)
ARTICLE
|
doi:10.20944/preprints202001.0219.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
protruding features; spherical virus; point arrays; surface modifications; VLP; drug delivery; icosahedral; nanomedicine; ligand binding
Online: 20 January 2020 (06:59:09 CET)
ARTICLE
|
doi:10.20944/preprints201908.0131.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
pharmacogenomics; immune checkpoint blockade; immunotherapy; drug response prediction; algorithm; mathematical model; precision medicine; personalized medicine
Online: 11 August 2019 (14:51:14 CEST)
ARTICLE
|
doi:10.20944/preprints202305.0524.v1
Subject:
Public Health And Healthcare,
Public, Environmental And Occupational Health
Keywords:
tobacco control; tobacco control legislation; tobacco control measures; tobacco control implementation scale; interrupted time series design; pneumonia hospitalisation rates; smoking-related hospitalisation rates
Online: 8 May 2023 (10:48:08 CEST)
REVIEW
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Parkinson’s disease; precision medicine; personalized medicine; GBA; Glucocerebrosidase; GCase; LRRK2; Leucine-rich repeat kinase-2; Dopamine; PD drug trials; PD risk variants
Online: 14 September 2020 (00:22:59 CEST)
ARTICLE
|
doi:10.20944/preprints202401.0575.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
Di(2-ethylhexyl) phthalate (DEHP); Endocrine disrupting compound (EDC); sex steroid receptor; Runt-related transcription factor 2 (Runx2); oxidant-antioxidant system; osteoblastic cells; bone
Online: 8 January 2024 (07:14:11 CET)
ARTICLE
|
doi:10.20944/preprints202301.0094.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Retinal pigment epithelium of the eye; RPE; AMD (Age-related Macular Degeneration); GPR143; L-DOPA; Melanin; Ocular albinism; Exosome; Photoreceptor outer segment; Cathepsin D.
Online: 5 January 2023 (02:58:31 CET)
REVIEW
|
doi:10.20944/preprints202408.2133.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
3D printing; corneal bioengineering; tissue engineering; barriers to eye care; bioinks; ocular prostheses; drug delivery systems
Online: 29 August 2024 (12:14:49 CEST)
ARTICLE
|
doi:10.20944/preprints202402.1376.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
keyword Glucose uptake, Yeast cell line, Abelmoschus esculentus L., Extract fractions, Type 2 diabetes, drug candidate.
Online: 23 February 2024 (11:21:02 CET)
REVIEW
|
doi:10.20944/preprints202312.0726.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
aerosol; nebulization; inhalation; airflow dynamics; particle deposition; particle-lung interactions; smart inhalers; AI in drug delivery
Online: 11 December 2023 (16:06:30 CET)
REVIEW
|
doi:10.20944/preprints202311.0094.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Casein Kinase II; Musculoskeletal; Osteoarthritis; Osteoporosis; CX-4945; CIBG-300; Cell Signaling; Drug Development; Targeted therapy
Online: 1 November 2023 (13:18:42 CET)
ARTICLE
|
doi:10.20944/preprints202309.2164.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Ewing sarcoma; drug synergy; Kinesin Family Member 11; Aurora Kinase A; SB-743921; and VIC-1911
Online: 30 September 2023 (08:26:49 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0274.v1
Subject:
Engineering,
Bioengineering
Keywords:
Fluorescence Imaging; Multispectral and hyperspectral imaging; Solvatochromic shift; Tunable Lasers; Spectroscopy; DMSO Sensing; Drug uptake monitoring
Online: 6 September 2023 (14:57:35 CEST)
REVIEW
|
doi:10.20944/preprints202306.0066.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Systems Biology; Multiomics; Cryptosporidium; Giardia; Entamoeba; Anti-Microbial Resistance; Multi Drug Resistance; Probiotic; Prebiotics, Synbiotics; Postbiotics
Online: 1 June 2023 (08:29:21 CEST)
REVIEW
|
doi:10.20944/preprints202305.1646.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
graphene-based nanomaterials; graphene-based drug delivery systems; lysosomes; cancer; endosomal/lysosomal escape; lysosomal cell death
Online: 23 May 2023 (10:52:24 CEST)
ARTICLE
|
doi:10.20944/preprints202209.0188.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
MTBC; virtual screening; topological indices; linear discriminant analysis; pharmacological activity distribution diagrams; antimicrobial drugs; drug design
Online: 14 September 2022 (03:32:55 CEST)
HYPOTHESIS
|
doi:10.20944/preprints202202.0032.v1
Subject:
Engineering,
Bioengineering
Keywords:
Organ-on-a-Chip (OoC); Micro-physiological systems (MPS); survey; usability; limitations; disease models; drug testing
Online: 2 February 2022 (12:20:19 CET)
REVIEW
|
doi:10.20944/preprints202101.0325.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
pediatric cancer; nanoparticles; drug delivery system; liposome; leukemia; lymphoma; osteosarcoma; Ewing sarcoma; glioma; blood-brain barrier
Online: 18 January 2021 (11:58:32 CET)
REVIEW
|
doi:10.20944/preprints202009.0405.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
horizontal gene transfer; bacterial conjugation; phenotypic conversion; drug-resistance dissemination; bacterial biofilms; mobile plasmids; F plasmid
Online: 17 September 2020 (12:00:29 CEST)
ARTICLE
|
doi:10.3390/sci2020045
Subject:
Medicine And Pharmacology,
Tropical Medicine
Keywords:
adverse drug reactions; antimalarial; Ghana; herbal remedies; malaria; questionnaire; street sale; orthodox; unnatural medicines; patient preference
Online: 12 June 2020 (00:00:00 CEST)
ARTICLE
|
doi:10.20944/preprints201912.0049.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
natural product; drug discovery; protoflavonoid; continuous-flow chemistry; oxime; antitumor; antiviral; epstein-barr virus; lytic cycle
Online: 4 December 2019 (11:40:33 CET)
ARTICLE
|
doi:10.20944/preprints201809.0292.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
monoglyceride colloidal liquid crystals; release profile; mathematical models; drug delivery systems; release kinetic; square root laws
Online: 17 September 2018 (09:33:52 CEST)
REVIEW
|
doi:10.20944/preprints201808.0204.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Alzheimer's disease; blood-brain barrier; cognitive aging; cognitive impairment; dementia; drug targeting; nanoemulsion; nanocarriers; scavenger receptors
Online: 10 August 2018 (12:28:34 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1050.v1
Subject:
Chemistry And Materials Science,
Applied Chemistry
Keywords:
transungual; antifungal nail lacquer; Itraconazole Nail Medication; Nail Drug Uptake; Nail penetration; Nail Plate Application; itraconazole hydrochloride; Topical Nail Polish; nail clipping; Nail Diffusion
Online: 15 August 2023 (07:06:34 CEST)
ARTICLE
|
doi:10.20944/preprints202408.0031.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
EMA; DGDA; Drug Regulatory Authorities; Manufacturing Guidelines; Quality Medicine; Good Laboratory Practice; cGMP; GMP; GLP; IPQC; QC; QA; Quality Control; Quality Assurance; Current Good Manufacturing Practice; Good Manufacturing Practice
Online: 1 August 2024 (11:15:43 CEST)
ARTICLE
|
doi:10.20944/preprints202202.0046.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Cancer; tumor homing peptide; in silico drug discovery; complex network; chemical space network; centrality measure; similarity searching, group fusion; motif discovery; starPep toolbox software
Online: 3 February 2022 (10:14:05 CET)
REVIEW
|
doi:10.20944/preprints202401.1078.v2
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
choroidal neovascularization; CNV; anti-VEGF resistance; neovascular age-related macular degeneration; AMD; arteriolar CNV; anti-VEGF therapies; anti-VEGF resistance; capillary CNV; AIBP; apoA-I
Online: 1 February 2024 (11:24:15 CET)
ARTICLE
|
doi:10.20944/preprints202408.1451.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
depression; adolescent girls; National Survey on Drug Use and Health; family structure; parenting style; negative school experience
Online: 20 August 2024 (13:44:36 CEST)
ARTICLE
|
doi:10.20944/preprints202407.1330.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
modular nanotransporters; targeted drug delivery; photosensitizers; anticancer drugs; photodynamic effect; epidermal growth factor receptors; binding; importins; Keap1
Online: 16 July 2024 (17:05:37 CEST)
ARTICLE
|
doi:10.20944/preprints202312.1002.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
intranasal spray; drug delivery; respiratory transport modeling; respiratory diseases; upper airway physiology; targeted nasal therapy; gentlemistTM technology
Online: 13 December 2023 (13:05:13 CET)
REVIEW
|
doi:10.20944/preprints202212.0048.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
poly(hexamethylene biguanide); polyhexamethylene biguanide; polyhexanide; PHMB; membrane; controlled drug release; wound dressing; antimicrobial; cytotoxicity; wound healing
Online: 2 December 2022 (10:31:38 CET)
ARTICLE
|
doi:10.20944/preprints202212.0013.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
poly(lactic-co-glycolic acid); silica; nanoparticles; enzymes; amino acid depletion; cancer; drug delivery; double emulsion; biocompatible
Online: 1 December 2022 (07:56:18 CET)