Search | Preprints.org

Preprint REVIEW | doi:10.20944/preprints202309.1520.v1

New Comprehension on Polycystic Ovary Syndrome and Sexual Function: A Systematic Review and Meta-Analysis

Fernanda S Bachega, Maria Cândida P Baracat, Ricardo Santos Simões, Gustavo A R Maciel, Roger A Lobo, José Maria Soares Jr, Edmund Chada Baracat

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: Stein-Leventhal Syndrome; Polycystic Ovary Syndrome; Sexuality; Sexual Activity; Sexual Dysfunction; Female Sexual Function Index; Sexual Function; Sexual Disorders; Sexual Behavior; Meta-analysis.

Online: 22 September 2023 (09:58:09 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202308.0229.v1

New Insights in the Detection and Management of Major Foliar and Root Diseases of Strawberries

Mahfuz Rahman, Jayesh Samtani, Aljawasim Baker

Subject: Biology And Life Sciences, Plant Sciences Keywords: Anthracnose fruit rot; Colletotrichum acutatum; Diagnostics; crop protection; sustainable management techniques; strawberry

Online: 3 August 2023 (10:08:31 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202302.0416.v2

Diphtheria and the AB Toxin Group: a History and the Need for New Toxin Therapeutics

Billy Pembroke

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: AB toxin; diphtheria; botulinum; tetanus; anthrax; cholera; pertussis; shiga toxin; vaccines

Online: 20 June 2023 (07:24:59 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201610.0051.v1

The Relationship between Residential Electricity Consumption and Income: A Piecewise Linear Model with Panel Data

Yanan Liu, Yixuan Gao, Yu Hao, Hua Liao

Subject: Business, Economics And Management, Econometrics And Statistics Keywords: residential electricity consumption; income; piecewise linear model; China; robust tests

Online: 14 October 2016 (09:53:13 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202407.0886.v1

A New Test Method of “Nuclear Magnetic Resonance + High-Speed Centrifugation” for Gas-Water Relative Permeability Curve of Low-Permeability and Tight Sandstone

Fenglai Yang, Huaxun Liu, Shusheng Gao, Sijie He, Feifei Fang, Cuili Wang, Liyou Ye, Kun Zhou, Xuejun Yang, Weiguo An

Subject: Physical Sciences, Fluids And Plasmas Physics Keywords: Low permeability and tight sandstone; Nuclear magnetic resonance (NMR); High speed centrifugation; Micro pore structure; Gas-water relative permeability curve

Online: 11 July 2024 (08:28:50 CEST)

Show abstract| Download PDF| Share

Gas-water relative permeability curve is the foundation of gas reservoir dynamic analysis and numerical simulation. It is generally obtained through gas displacing water experiment. Referring to the existing national standards, gas-water relative permeability test is carried out for low-permeability and tight sandstone. The flow is discontinuous and the curve smoothness is poor, which affects the application of gas-water relative permeability curve. Based on the comparative analysis of a large number of mercury injection and NMR experimental results of low-permeability and tight sandstone, a method to characterize the throat radius distribution of low-permeability tight sandstone based on NMR T2 spectrum is explored. Combined with high-speed centrifugal experiment, the calculation formulas of core water saturation, phase relative permeability of gas-water under different centrifugal force are established. A new method of "nuclear magnetic resonance + high-speed centrifugation" for gas-water relative permeability curve test of low-permeability and tight sandstone is formed, and the test is carried out on Sulige low-permeability tight sandstone core. The results show that: (1) The shape of cumulative distribution curve of throat radius by mercury injection method is basically consistent with that of T2 relaxation time by NMR, and there is a good corresponding relationship between them. (2) The centrifugation process is similar to the gas displacing water process. With the decrease of water saturation, water centrifugation in rock core becomes more and more difficult until it become irreducible. (3) The test process of the new method is unified and standard and up to 6 cores can be tested at the same time. The calculation results of water saturation and relative permeability curve are reliable and the integral curve is smooth, which greatly improves the test efficiency of gas-water relative permeability curve in low-permeability and tight sandstone. The new method can be widely used to study the gas-water two-phase seepage law in low-permeability and tight sandstone gas reservoir.

Preprint ARTICLE | doi:10.20944/preprints201612.0145.v1

Structural Insights into Thermotoga maritima FtsH Periplasmic Domain on Substrate Recognition

Jun Yop An, Humayun Sharif, Gil Bu Kang, Kyung Jin Park, Jung-Gyu Lee, Sukyeong Lee, Mi Sun Jin, Ji-Joon Song, Jimin Wang, Soo Hyun Eom

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: ATP-dependent proteolysis, Non-native membrane proteins, Periplasmic domain, Crystal structure, Photosystem II.

Online: 29 December 2016 (17:16:52 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202409.1076.v1

An Overview of Current and New Data Quality Dimensions under a Common Framework

Russell Miller, Harvey Whelan, Michael Chrubasik, David Whittaker, Paul Duncan, João Gregório

Subject: Computer Science And Mathematics, Computer Science Keywords: data quality; data model; data quality dimensions; data traceability; confidence in data; data metrology; data uncertainty; data structures; big data; IoT

Online: 13 September 2024 (10:39:28 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202408.1157.v1

Keisuke Kokubun

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Information and Communication Technology; smartphone; older adults

Online: 15 August 2024 (11:58:26 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202407.1285.v1

A New Perspective to the Relation Between Accretion Luminosity and Mass Accretion Rate

Stefania Pezzuto

Subject: Physical Sciences, Astronomy And Astrophysics Keywords: Accretion; Star formation; Supermassive black holes

Online: 16 July 2024 (08:25:55 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202407.0540.v1

Invasive Candida Infections in the NICU. Risk Factors and New Insights in Prevention

Niki Dermitzaki, Maria Baltogianni, Efrosini Tsekoura, Vasileios Giapros

Subject: Biology And Life Sciences, Other Keywords: invasive candida infections; neonatal candidiasis; antifungal prophylaxis; fluconazole prophylaxis

Online: 9 July 2024 (06:06:24 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202405.1277.v1

Development of new edible biodegradable films containing camu-camu and agro-industry residue

Huéberton Naves, Ana Paula Stafussa, Grasiele Madrona, Fabrício Tanaka, Fauze Aouada, Márcia Regina de Moura

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: Myrciaria dubia (H. B. K.) Mcvaugh; Gelatin; Glycerol; Biodegradable; Antioxidants.

Online: 20 May 2024 (11:52:07 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202405.1099.v1

Empowering New-Quality Productivity Development through Artificial Intelligence: Impact Mechanisms and Spatial Spillover

Xuesong Gao, Xuefang Liu

Subject: Business, Economics And Management, Econometrics And Statistics Keywords: Artificial Intelligence; New-Quality Productivity; Kernel Density Estimation; Moran's I Index; Two-Way Fixed Effects Model; Mediation Effect Model; Spatial Durbin Model

Online: 16 May 2024 (12:02:55 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202404.0478.v1

New Pyranone Derivatives and Sesquiterpenoid Isolated from the Endophytic Fungus Xylaria sp. Z184

Yan Zhang, Yang Jin, Wensi Yan, Peishan Gu, Ziqian Zeng, Ziying Li, Guangtao Zhang, Mi Wei, Yongbo Xue

Subject: Chemistry And Materials Science, Organic Chemistry Keywords: Xylaria sp.; pyranone derivative; sesquiterpenoid; antimicrobial activity

Online: 8 April 2024 (16:42:40 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint REVIEW | doi:10.20944/preprints202401.1614.v1

Optimizing Mesenchymal Stromal Cells Delivery: Present Status and New Frontiers in Regenerative Medicine

Jayeeta Giri

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Mesenchymal stromal cells; route of delivery; dose; Immunogenicity; Metabolic fitness; Potency assay

Online: 23 January 2024 (09:15:47 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202311.1562.v1

A Comprehensive Study and Analysis of 3GPP’s 5G New Radio for V2X Communication

G. G. Md. Nawaz Ali, Mohammad Nazmus Sadat, Md Suruz Miah, Sameer Ahmed Sharief, Yun Wang

Subject: Computer Science And Mathematics, Computer Networks And Communications Keywords: 5G NR V2X; 3GPP; C-V2X; Connected vehicle; ns-3 simulation; V2X communication; Performance analysis

Online: 24 November 2023 (11:26:39 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202309.2161.v1

New Graph-Based and Transformers Deep Learning Models for River Dissolved Oxygen Forecasting

Paulo Alexandre Costa Rocha, Victor Oliveira Santos, Jesse Van Griensven Thé, Bahram Gharabaghi

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: pollution; dissolved oxygen; Credit River; machine learning; graph neural networks; SHAP analysis

Online: 30 September 2023 (08:15:54 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202309.2116.v1

Hydrodynamic Design and Array System Study of a New Floating Wave Energy Device

Yu Zhang, Dongqin Li

Subject: Engineering, Marine Engineering Keywords: Wave power generation; Oscillating float; Computational Fluid Dynamics; Array

Online: 30 September 2023 (07:55:14 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202307.0994.v1

Mycobacterium avium ssp. Paratuberculosis and Crohn’s Disease—Time to Consider New Therapeutic Approaches?

John M Aitken, Jack E Aitken, Gaurav Agrawal

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: cell wall deficient mycobacteria; Mycobacterium paratuberculosis; Crohn’s disease; Ziehl-Neelsen stain; non-tuberculosis mycobacteria

Online: 14 July 2023 (08:47:26 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202307.0773.v1

A New Definition of Dual Spline Curves for Curve Modeling and Geometry Defeaturing

Baotao Chi, Shengmin Bai, Qianjian Guo, Yaoming Zhang, Wei Yuan, Can Li

Subject: Computer Science And Mathematics, Geometry And Topology Keywords: Dual spline curves; Adaptive curve refinement; Curve modeling; Geometry defeaturing

Online: 12 July 2023 (05:50:49 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202306.1619.v1

New Insights in Fracture Porosity Estimation using Machine Learning and Advanced Logging Tools

Ghoulem Ifrene, Doina Irofti, Ruichong Ni, Sven Egenhoff, Prasad Pothana

Subject: Engineering, Other Keywords: Machine learning; SVM; ANN; Fracture porosity prediction; Anisotropy; Well logging; Shear waves; Image logs.

Online: 22 June 2023 (12:15:56 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202306.1445.v1

Linguistic Communication Channels Reveal Connections Between Texts: The New Testament and Greek Literature

Emilio Matricciani

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: Apocalypse; Deep‒language; Greek New Testament; Greek Classical Literature; Epistle to the Hebres; Interpunctions; Likeness index; Linguistic channels; Sentences; Signal‒to‒noise ratio; Vectors;

Online: 20 June 2023 (13:59:20 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202303.0462.v1

Acoustic Emissions in Rock Deformation and Failure: New Insights from Q-Statistical Analysis

Sergio Vinciguerra, Annalisa Greco, Alessandro Pluchino, Andrea Rapisarda, Constantino Tsallis

Subject: Environmental And Earth Sciences, Geochemistry And Petrology Keywords: Acoustic emissions; q-statistics; rocks fractures

Online: 27 March 2023 (13:30:55 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202303.0125.v1

New Species of Protists Involved in Meningitis and Encephalitis in Peru: Morphology Description

Alfonso Martín Cabello-Vílchez

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Amoeba; Meningitis; Meningoencephalitis; free-living amoeba; Peru

Online: 7 March 2023 (03:44:06 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202204.0041.v1

Magnetoliposomes Containing Multicore Nanoparticles and a New Thienopyridine Antitumor Compound for Chemo/Thermotherapy

Fábio A. C. Lopes, André V. F. Fernandes, Juliana M. Rodrigues, Maria-João R. P. Queiroz, Bernardo G. Almeida, Ana Pires, André M. Pereira, João P. Araújo, Ana Rita O. Rodrigues, Elisabete M. S. Castanheira, Paulo J. G. Coutinho

Subject: Chemistry And Materials Science, Biomaterials Keywords: multicore magnetic nanoparticles; magnetoliposomes; magnetic hyperthermia; antitumor thienopyridine derivative; chemotherapy

Online: 6 April 2022 (10:27:22 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202112.0395.v1

Nutraceutical Content and Genetic Diversity Share a Common Pattern in New Pomegranate Genotypes

Carmen Arlotta, Valeria Toscano, Claudia Genovese, Pietro Calderaro, Giuseppe Diego Puglia, Salvatore Antonino Raccuia

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Punica granatum L.; Bio-agronomic traits; Antioxidant activity; Total phenolic content; Carbohydrates; Minerals; genetic diversity

Online: 23 December 2021 (14:12:35 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202105.0078.v1

New Governance Through Digital Platforms and the Old Urban Planning Process in Italy

Cinzia Bellone, Fabio Naselli, Fabio Andreassi

Subject: Social Sciences, Anthropology Keywords: Urban planning Italy; Governance 3.0; New Digital Platforms; Sentiment Analysis

Online: 6 May 2021 (12:27:35 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202104.0228.v1

Holistic Requirements Analysis For Specifying New Systems For 3D Media Production and Promotion

Christos Mouzakis, Dimitrios Ververidis, Luis Miguel Girao, Nicolas Patz, Spiros Nikolopoulos, Ioannis Kompatsiaris

Subject: Social Sciences, Anthropology Keywords: Requirements Engineering; Authoring Tools; 3D content; IEEE 830 standard; Social Media

Online: 8 April 2021 (10:16:52 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202011.0333.v1

Dual Aquaporin and Sigma1 Receptor (DAS) Modulators: New Tools for Counteracting Oxidative Stress

Giorgia Pellavio, Giacomo Rossino, Giulia Gastaldi, Daniela Rossi, Pasquale Linciano, Simona Collina, Umberto Laforenza

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: peroxiporins; oxidative stress; hydrogen peroxide; water channels; Sigma1 receptors; Sigma1 receptor modulators; neurodegenerative diseases

Online: 12 November 2020 (09:33:34 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202009.0706.v1

A New Endemic of Concomitant Nonalcoholic Fatty Liver Disease and Chronic Hepatitis B

Hira Hanif, Muzammil Khan, Mukarram Ali, Pir Shah, Jinendra Satiya, Daryl Lau, Aysha Aslam

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Chronic hepatitis B; NAFLD; NASH; biomarkers; magnetic resonance technology; NAFLD therapy

Online: 29 September 2020 (10:40:21 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202007.0699.v1

Relationship between Climate Variables and New Daily COVID-19 Cases in Dhaka, Bangladesh

M. Mofijur, Islam Md Rizwanul Fattah, A. B. M. Saiful Islam, S.M. Ashrafur Rahman, Mohammad Asaduzzaman Chowdhury

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: COVID-19; Climate indicators; Air Quality; Environment; Pandemic; Coronavirus

Online: 29 July 2020 (12:35:36 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202007.0609.v1

PyAtomDB: Extending the AtomDB Atomic Database to Model New Plasma Processes and Uncertainties

Adam R. Foster, Keri Heuer

Subject: Physical Sciences, Astronomy And Astrophysics Keywords: X-ray Spectroscopy; Atomic Data; Spectral Analysis; Error Analysis

Online: 25 July 2020 (15:29:30 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202007.0202.v1

A Note on a New Type of Degenerate poly-Euler Numbers and Polynomials

Waseem Khan

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: degenerate polylogarithm functions; degenerate poly-Euler polynomials; degenerate unipoly functions; degenerate unipoly-Euler polynomials

Online: 10 July 2020 (03:39:58 CEST)

Show abstract| Download PDF| Share

Preprint HYPOTHESIS | doi:10.20944/preprints202002.0363.v1

Exceptionally Rare Genomic Combinations to Skip Sex: Blending Old Ideas and New Data

Diego Hojsgaard, Manfred Schartl

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: amphimixis; apomixis; gynogenesis; hybridogenesis; parthenogenesis

Online: 25 February 2020 (06:40:06 CET)

Show abstract| Download PDF| Share

The unusual occurrence and developmental diversity of asexual eukaryotes still remain a puzzle. Despite asexual organisms have a theorized two-fold reproductive advantage over sexuals, asexual lineages are rare among multicellular eukaryotes. Justification of such disparity relies on the consequences of a lack of meiosis, which restricts genotype diversity and adaptation to novel conditions while accelerating the genetic degeneration that drives asexual lineages to an early demise. However, evidence indicates asexuals use different strategies to limit negative consequences of ameiosis, and age estimates show some asexual vertebrates and plants are much older than expected. If rapid extinction is not a factor influencing asexuals lifespan, then why asexuals are not more frequent? Here we review traditional ideas and new data and provide a novel unified evolutionary frame to understand the intriguing nature, developmental diversity and maintenance of asexual lineages. As a rule, de novo formation of a functioning asexual genome requires a unique assemblage combining particular sets of genes or gene states to disrupt cellular mechanisms of meiosis and gametogenesis, and affect discrete components of sexuality to produce clonal or hemiclonal offspring. We highlight two usually overlooked but essential conditions to understand the molecular nature of clonal organisms, i.e. a non-recombinant genomic assemblage retaining modifiers of the sexual program, and a complementation between altered reproductive components. These subtle conditions are the basis for physiologically viable and genetically balanced transitions between generations. Genomic and developmental evidence from asexual animals and plants indicates the lack of complementation of molecular changes in the sexual reproductive program is likely the main cause of asexuals' rarity, and can provide an explanatory frame for the developmental diversity and lability of developmental patterns in some asexuals as well as for the discordant time to extinction estimations.

Preprint ARTICLE | doi:10.20944/preprints201908.0093.v2

Extraction of Polyphenols and Synthesis of New Activated Carbon from Spent Coffee Grounds

Marina Ramón-Gonçalves, Lorena Alcaraz, Susana Pérez Ferreras, María Eugenia León-González, Noelia Rosales Conrado, Félix Antonio López

Subject: Chemistry And Materials Science, Food Chemistry Keywords: spent coffee grounds; polyphenols; extraction; subcritical fluid; activated carbon; methylene blue; adsorption.

Online: 20 September 2019 (10:23:51 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints201909.0170.v1

ARSA-16S: A New and Conceptually Different Approach for 16S-based Taxonomic Profiling

Eduardo Pareja-Tobes, Raquel Tobes

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: 16S analysis, metagenomics, amplicons, bioinformatics, DNA sequencing

Online: 16 September 2019 (16:41:43 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints201811.0409.v1

G-Quadruplex targeting ligands: A hope and a new horizon in Cancer Therapeutics

Nilanjan Banerjee, Suman Panda, Subhrangsu Chatterjee

Subject: Chemistry And Materials Science, Medicinal Chemistry Keywords: G quadruplex, Oncogene, ligand, cancer

Online: 16 November 2018 (11:34:24 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201809.0468.v1

New “Smart” Systems for Atmospheric Aerosol and Reactive Gas Sampling in Ambient Air

Paolo Cristofanelli, Maurizio Busetto, Enrico Ronchi, Paolo Miatto, Angela Marinoni, Francescopiero Calzolari, Paolo Bonasoni, Luca Tagliafico

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: reactive gases; atmospheric aerosol; air sampling; smart technologies

Online: 24 September 2018 (16:47:52 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201805.0196.v1

New Tetrahydroisoquinoline Derivatives Overcome Pgp Activity in Brain-Blood Barrier and Glioblastoma Multiforme

Iris Chiara Salaroglio, Elena Gazzano, Joanna Kopecka, Konstantin Chegaev, Costanzo Costamagna, Roberta Fruttero, Stefano Guglielmo, Chiara Riganti

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: P-glycoprotein; glioblastoma multiforme; brain-blood barrier; doxorubicin

Online: 14 May 2018 (12:50:18 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint REVIEW | doi:10.20944/preprints201805.0086.v1

Irrigation Water Quality and Soil Structural Stability: A Perspective with Some New Insights

Pichu Rengasamy

Subject: Environmental And Earth Sciences, Environmental Science Keywords: water quality; soil structure; threshold electrolyte concentration; zero point of dispersion

Online: 4 May 2018 (07:53:35 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201608.0212.v1

FDI Inflows, Price and Exchange Rate Volatility: New Empirical Evidence from Latin America

Silvia Dal Bianco, Loan Nguyen Cong To

Subject: Business, Economics And Management, Economics Keywords: FDI; GARCH; real exchange rate and price volatility; Latin America and the Caribbean

Online: 26 August 2016 (09:59:32 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202406.1255.v1

Revolutionizing Eye Care: Exploring the Potential of Microneedle Drug Delivery

Satish Rojekar, Swapnali Parit, Amol D. Gholap, Ajit Manchare, Sopan N Nangare, Navnath T Hatvate, Vrushabh V. Sugandhi, Keshav Raj Paudel, Rahul G Ingle

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Eye care; Glaucoma; Biocompatibility; Microneedles; Ocular drug delivery

Online: 19 June 2024 (04:15:08 CEST)

Show abstract| Download PDF| Share

Microneedle technology is a novel platform technology that revolutionizes ocular drug delivery and addresses critical challenges in the treatment of ocular diseases. Routine treatment methods, such as eye drops and intravitreal injections, suffer from low bioavailability and poor patient compliance. So, novel advanced platform technologies are required to overcome these challenges. Microneedle is a minimally invasive and promising alternative technique that helps precisely control drug delivery to targeted tissues and organs. This review investigates the potential impact of microneedle technology for eye care, underscoring recent advancements, underlying mechanisms, and emerging preclinical and clinical uses. Different types of microneedles, including solid, coated, dissolvable, and hollow, have demonstrated their potential and capability to bypass several barriers in the cornea and sclera. This ensures effective drug penetration and delivery. The current innovations in material science and fabrication methods have enhanced the safety and efficacy of microneedles, reducing discomfort and the chances of infections. These microneedle technologies offer sustained and controlled drug delivery, which could improve therapeutic outcomes for various disease conditions like age-related macular degeneration, glaucoma, diabetic neuropathy, etc. In the current review, recent preclinical and clinical studies emphasize microneedle-based ocular drug delivery's feasibility and potential benefits. These include improved pharmacokinetics, reduced dosing frequency, enhanced patient adherence, and, most importantly, microneedles offer versatile platforms for delivering a wide range of small and large molecules and gene therapies. Despite the exciting progress, obstacles such as regulatory barriers, scalability, and long-term biocompatibility persist. It will be essential to tackle these challenges through interdisciplinary research and partnerships to integrate microneedle technology into standard clinical use effectively. Ultimately, microneedle drug delivery offers a revolutionary method that has the potential to significantly enhance the treatment and results of ocular diseases, marking the dawn of a new era in eye care.

Preprint ARTICLE | doi:10.20944/preprints202408.0004.v1

Ensuring Operational Performance and Environmental Sustainability of Marine Diesel Engines through the Use of Biodiesel Fuel

Sergii Sagin, Oleksiy Kuropyatnyk, Oleksii Matieiko, Roman Razinkin, Tymur Stoliaryk, Oleksandr Volkov

Subject: Engineering, Marine Engineering Keywords: alternative fuel; biofuel; marine diesel; specific fuel oil consumption; environmental sustainability; diesel performance; nitrogen oxide emission

Online: 1 August 2024 (10:57:16 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202312.0947.v1

Expression of FAD and SAD Genes in Developing Seeds of Flax Varieties under Different Growth Conditions

Elena N. Pushkova, Liubov V. Povkhova, Ekaterina M. Dvorianinova, Roman O. Novakovskiy, Tatiana A. Rozhmina, Aleksey A. Gryzunov, Elizaveta A. Sigova, Daiana A. Zhernova, Elena V. Borkhert, Anastasia A. Turba, Arthur G. Yablokov, Nadezhda L. Bolsheva, Alexey A. Dmitriev, Nataliya V. Melnikova

Subject: Biology And Life Sciences, Plant Sciences Keywords: Linum usitatissimum; flax; fatty acids; SAD; FAD; gene expression; transcriptome sequencing

Online: 13 December 2023 (05:20:29 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202307.0303.v1

Biotechnological Potential of the Stress Response and Plant Cell Death Regulators Proteins in the Biofuel Industry

Maciej Jerzy Bernacki, Jakub Mielecki, Andrzej Antczak, Michał Drożdżek, Damin Witoń, Joanna Dąbrowska-Bronk, Piotr Gawroński, Paweł Burdiak, Monika Marchwicka, Anna Rusaczonek, Katarzyna Dąbkowska-Susfał, Wacław Roman Strobel, Ewa Mellerowicz, Janusz Zawadzki, Magdalena Szechyńska-Hebda, Stanisław Karpiński

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: stress response; poplar; lignin; bioethanol; cell wall; cell death; biofuels; stress response proteins

Online: 6 July 2023 (03:28:59 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202308.0466.v1

Expanding the Analytical Toolbox: Developing New Peptide Map Methods to Fully Characterize the Proteolysis-resistant Single-domain Antibody New Modality

Y Diana Liu, Michelle Irwin Beardsley, Feng Yang

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: Biopharmaceuticals; drug substances; sample preparation; mass spectrometry

Online: 7 August 2023 (10:01:54 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202307.1377.v1

The First Case of Zika Virus Disease in Guinea: Description, Virus Isolation, Sequencing and Seroprevalence in Local Population

Roman Bayandin, Marat T. Makenov, Sanaba Boumbaly, Olga A. Stukolova, Anastasia V. Gladysheva, Andrey V. Shipovalov, Maksim O. Skarnovich, Ousmane Camara, Aboubacar Hady Toure, Victor A. Svyatchenko, Alexander N. Shvalov, Vladimir A. Ternovoi, Mamadou Y. Boiro, Alexander P. Agafonov, Lyudmila S. Karan

Subject: Biology And Life Sciences, Virology Keywords: Zika virus; seroprevalence; flavivirus; arbovirus; fever; mosquito-borne virus; vector-borne virus

Online: 20 July 2023 (04:51:12 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201811.0054.v2

A Review and Introduction to New Aspects of Digital and Computational Approaches to Human and AI Ethics

Hector Zenil

Subject: Arts And Humanities, Philosophy Keywords: philosophy of information; organised complexity; Kolmogorov complexity; logical depth; ethics of information; computational ethics; infoethics; machine ethics; computational complexity

Online: 20 December 2018 (05:34:55 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202405.0797.v1

CRYSTAL GROWTH AND SPECTROSCOPY OF Yb2+ DOPED CsI SINGLE CRYSTAL

Dmitriy Sofich, Alexandra Myasnikova, Alexander Bogdanov, Viktorija Pankratova, Vladimir Pankratov, Ekaterina Kaneva, Roman Yu. Shendrik

Subject: Physical Sciences, Condensed Matter Physics Keywords: cesium iodide; ytterbium; luminescence; single crystal; Czochralski method

Online: 13 May 2024 (07:48:17 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202409.0511.v1

Evaluation of the Impact of Advanced Glycation End-Products on Peripheral Neuropathy Outcomes in Type 2 Diabetes

Indumathi Singh, Tushar Issar, Ann Poynten, Kerry-lee Milner, Arun V Krishnan, Roshan Dhanapalaratnam

Subject: Medicine And Pharmacology, Endocrinology And Metabolism Keywords: Advanced glycation end products; diabetic peripheral neuropathy

Online: 6 September 2024 (09:40:34 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202405.1488.v1

Loss of Independence after Index Hospitalization Following Proximal Femur Fracture: A Narrative Review

Hannan A. Maqsood, Adam Pearl, Awni Shahait, Basmah Shahid, Santosh Parajuli, Khalid J. Saleh

Subject: Medicine And Pharmacology, Surgery Keywords: Loss of independence; proximal femur fracture; geriatric patients; frailty measures; Disposition; Economic Impacts; Psychological Impacts

Online: 23 May 2024 (07:35:21 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202409.1855.v1

Antimicrobial Susceptibility of Uropathogenic Escherichia coli with Analysis of Impact of Socio-Economic Factors in Low, Medium and High-Income Countries

Meher Rizvi, Maria Khan, Amina AL Jardani, Ujjala Ghoshal, Zaaima AL Jabri, Mohammad Ahanjan, Azza AL Mamari, Nawal AL Shizawi, Hiba Sami, Abdullah Balkhair, Adila Shaukat, Alwarith Nasser Salem Alkharusi, Abdulrahman Almahrouqi, Afreenish Hassan, Ajay Kumar, Amal Malehi, Amina Gul, Ashima Singh, Asma Said Hamed AL Shidhani, Areena Hoda Siddiqui, Aruna Poojary, Azza AL Rashdi, Bradley Langford, Dmytro Stepanskyi, Abbas Dolatabadi, Aisha Al Mufraji AL Mufraji, Elham Said Ahmed AL Risi, Garima Kapoor, Isabella Princess, Hatim Ali Eltahir, Hilal Al Sidairi, Kaitlyn Dougherty, Katia Iskandar, Ken Masters, Ibrahim Khalaf Hamdan AL Busaidi, Laila AL Yazidi, Mahfuza Nasrin, Mahmood Salim AL Subhi, Mallika Sengupta Mallika Sengupta, Manisha Khandait, Nada Khalfan AL Tamtami, Nada Khafan Alsiyabi, Nawal AL Kindi, Nazla Musthafa Luthfee, Neha Shreshtha, Nihal Mohamed Amur AL Riyami, Noora Hilal Ali AL Busaidi, Nupur Goel, Oksana Ishchenko, Omnia Mohamed Elnabawy Ahmed Taher, Pragnya Paramita Jena, Rajni Ekadashi, Razan Zadjali, Reba Kanungo, Sara Abolghasemi, Salima Al-maqbali, Sanjay Jaju, Sayantan Banerjee, Shadma Yaqoob, Shahnaz Sali, Shafqat Husnain Khan, Shalini Malhotra, Stephen Hughes, Sundas Shaukat, Syed Mohammed Atif, Vrushali Vishwas Patwardhan, Victorien Dougnon, Wahid Khan, Walid Wali, Zakariya AL Muharrmi, Zeeshana Basit, Jasashree Choudhury, Rachita Pravalina, Sanjeev Singh, Sarman Singh, Neelam Taneja, Raman Sardana, Pawan Kapoor, Rajeev Soman, Rashid Al Abri

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: community acquired UTI; Escherichia coli; antimicrobial susceptibility; Indian subcontinent; MENA; GDP; temperature

Online: 24 September 2024 (12:32:05 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint CONCEPT PAPER | doi:10.20944/preprints202410.0712.v1

New Number System: An Extension of Binary Arithmetic

Haoyuan Wang

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: binary; communicative group; communicative ring

Online: 9 October 2024 (14:25:57 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202408.1680.v1

A New Measure of Risk Using Fourier Analysis

Michael Grabinski, Galiya Klinkova

Subject: Business, Economics And Management, Finance Keywords: finance; risk; Fourier; crypto currencies; stock market; conserved value

Online: 23 August 2024 (11:13:24 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202406.1250.v1

Identification of New Polymorphic Patterns for Elacestrant Dihydrochloride

Zia Uddin Masum, P Grant Spoors, Matt D Burke, Vivek Gupta

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Polymorphism; Elacestrant; Characterization; Amorphous; Crystalline; Anti-solvent Addition; Polymer Templating; Solvent-Drop Grinding

Online: 19 June 2024 (02:42:05 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint COMMUNICATION | doi:10.20944/preprints202405.0001.v1

New Strategies in the Control of Graves’ Disease

Seongtaek Seo, Jose Manuel Abalo-Lojo, Juan M Vazquez-Lago

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Graves' disease; hyperthyroidism; Graves' ophthalmopathy; antithyroid drugs; stress

Online: 1 May 2024 (02:30:35 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202402.0923.v1

A New Landscape for Southwest Ozark Missouri Woodlands?

Akeem Ajao, Sanjeev Sharma, D Alexander Wait, Puskar Khanal

Subject: Environmental And Earth Sciences, Ecology Keywords: woodland; regression; t-test; specific leaf weight; decomposition

Online: 18 February 2024 (11:49:46 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202402.0268.v1

A New Cloud‐Native Tool for Pharmacogenetic Analysis

David Yu Yuan, Jun Hyuk Park, Zhenyu Li, Rohan Thomas, David M Hwang, Lei Fu

Subject: Computer Science And Mathematics, Software Keywords: Pharmacogenetics; bioinformatics pipeline; cloud‐native technologies; workflow; genomic data analysis

Online: 5 February 2024 (10:54:41 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202401.1227.v1

CFD Analysis for a New Trombe Wall Concept

Alexandru Mihai Bulmez, Alin Ionuț Brezeanu, George Dragomir, Mariana Fratu, Nicolae Fani Iordan, Sorin Ionuț Bolocan, Lucian Rozorea, Eugen Călin Popa, Gabriel Năstase

Subject: Engineering, Architecture, Building And Construction Keywords: Trombe wall; ventilation; envelope; CFD; envelope; performance improvements

Online: 16 January 2024 (13:33:44 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202312.0331.v1

Idiopathic Toe Walking: What’s New? An Integrative Review

Letícia D’Ordaz Lhano Santos, Talissa Oliveira Generoso, Luiz Renato Agrizzi De Angeli, Francesco Camara Blumetti, Filipe Machado Barcelos

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: Idiopathic Toe Walking; Equinus Gait; Tip Toe Walking; Toe Walking Behavior; Treatment; Narrative Review.

Online: 6 December 2023 (07:56:08 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202311.0488.v1

New Generation Sustainable Technologies for Soilless Vegetable Production

Fernando Fuentes-Peñailillo, Karen Gutter, Ricardo Vega, Gilda Carrasco Silva

Subject: Engineering, Bioengineering Keywords: Horticulture; hydroponics; digital agriculture; sustainability; sustainable production

Online: 7 November 2023 (15:50:00 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202310.0447.v1

Ethical Considerations for Echinoderms: New Initiatives in Welfare

Augusto César Crespi-Abril, Tamara Rubilar

Subject: Biology And Life Sciences, Life Sciences Keywords: echinoderms welfare; 5 R’s principle; respect; responsibility; Invertebrates; Responsible echinoderms use; Echinoderms sentience

Online: 8 October 2023 (11:48:51 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202310.0343.v1

A New Solution to the Strong CP Problem

Sergey Larin

Subject: Physical Sciences, Particle And Field Physics Keywords: Quantum Chromodynamics; renormalizability; axions; CP violation; charge conjugation C; space reflection P

Online: 7 October 2023 (02:58:27 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202309.0620.v1

A New Model of Gravity at Large Distances

Naman Kumar

Subject: Physical Sciences, Astronomy And Astrophysics Keywords: dark matter; 2D dilaton gravity; MOND; modified gravity

Online: 11 September 2023 (05:27:22 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202309.0022.v1

Multinanozyme Systems: The New Generation of Nanozymatic Systems

Saeed Reza Hormozi Jangi

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: nanozymes; multinanozyme system; nanozyme-based sensing and detection

Online: 1 September 2023 (10:54:43 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202307.1348.v1

Extensive Validation of a New Rock Breakage Test

Marcos De Paiva Bueno, Thiago Almeida, Malcolm S. Powell

Subject: Engineering, Mining And Mineral Processing Keywords: Geometallurgy; comminution; ore characterization; variability; breakage test

Online: 20 July 2023 (08:34:45 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202306.2260.v1

New Trends to Treat Muscular Atrophy: Systematic Review

Iris Jasmin Santos German, Karina Torres, Jesus Carlos Andreo, Joao Shindo, Camila Dallantonia, Luiza Haber, Cláudia Rucco Penteado Detregiachi, Adriano Araujo, Elen Landgraf Guiguer, Raul Girio, Patricia Bueno, Maricelma Souza, Marcia Rocha, Sandra Maria Barbalho, Andre Shinohara

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: epicatechin; skeletal muscle; muscular atrophy; catechins; myogenic regulatory factors

Online: 30 June 2023 (14:49:48 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202306.0107.v1

A New RSA Variant Based on Elliptic Curves

Maher Boudabra, Abderrahmane Nitaj

Subject: Computer Science And Mathematics, Information Systems Keywords: Public key Cryptography; RSA; KMOV; Demytko’s scheme; Elliptic curves; Continued fractions; Coppersmith’s method.

Online: 1 June 2023 (15:37:57 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202304.0707.v1

Pankun: A New Generation Broadband Ocean Bottom Seismograph

Dan Liu, Ting Yang, Yizhi Wang, Yuechu Wu, Xinfeng Huang

Subject: Engineering, Marine Engineering Keywords: ocean bottom seismograph (OBS); seismometer; digitizer; leveling system

Online: 21 April 2023 (09:51:24 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202211.0465.v1

New Insights into the Biological Activities of Carboxymethylated

Matheus Cerdeira Pires, Natalia de Gois Andriolo, Bruno Rafael Pereira Lopes, Camila Delarmelina, Marta Cristina Teixeira Duarte, Ana Lucia Tasca Gois Ruiz, Valeria Marta Gomes Do Nascimento, Karina Alves De Toledo, Catarina Dos Santos

Subject: Chemistry And Materials Science, Organic Chemistry Keywords: Lasiodiplodan; Anticoagulant; Immunomodulatory Activity; Antiviral activities

Online: 25 November 2022 (02:52:37 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202203.0133.v1

A New Technique to Repair Large Bone Defects

Takaaki Tanaka, Hirokazu Komaki, Naoya Inagaki, Shoshi Akiyama, Mitsuru Saito

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: bone formation; BMP-2; FGF-2; beta-TCP; osteoblast-osteoclast communication

Online: 9 March 2022 (10:58:33 CET)

Show abstract| Download PDF| Share

Preprint CONCEPT PAPER | doi:10.20944/preprints202202.0202.v1

A New Look at the Concept of Ecosystem

Jaime Gomez-Marquez

Subject: Biology And Life Sciences, Ecology, Evolution, Behavior And Systematics Keywords: ecosystem concept; ecosystem hallmarks; ecosystem representation; living worlds

Online: 17 February 2022 (06:45:22 CET)

Show abstract| Download PDF| Share

Preprint COMMUNICATION | doi:10.20944/preprints202111.0492.v1

A New Taxon of Sideroxylon mascatense in Oman

Eric Hopkins, Rashid Al-Yahyai, Shahina Ghazanfar

Subject: Biology And Life Sciences, Plant Sciences Keywords: Sideroxylon mascatense; Oman; Western Hajar Mountains

Online: 26 November 2021 (08:33:28 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202111.0193.v1

The Concept of “New Media” Among News Producers

Shlash Alzyoud

Subject: Social Sciences, Media Studies Keywords: Social media; Professional journalism; Journalists; Citizen Journalism.

Online: 10 November 2021 (08:38:38 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202109.0118.v1

A New Method for Calculating Energy of Matter

Qing Li

Subject: Physical Sciences, Mathematical Physics Keywords: mass energy formula; space/time; the camparable finity

Online: 7 September 2021 (10:35:38 CEST)

Show abstract| Download PDF| Share

Working Paper REVIEW

Peer Group : A New Approach Of Nursing Intervention

Suyanto Suyanto, Moses Glorino Rumambo Pandin

Subject: Public Health And Healthcare, Nursing Keywords: peer group support; peer group education and technology

Online: 15 April 2021 (10:28:41 CEST)

Show abstract| Download PDF| Share

Preprint CONCEPT PAPER | doi:10.20944/preprints202104.0281.v1

The Concept of Engineering & Humanities: A New discipline

Haoxuan Yu, Shuai Li, Xinmin Wang

Subject: Engineering, Automotive Engineering Keywords: Engineering; Humanities; Discipline

Online: 12 April 2021 (11:59:07 CEST)

Show abstract| Download PDF| Share

Working Paper ARTICLE

Back There: Finding Polity in New Jack City

Fallen Matthews

Subject: Social Sciences, Urban Studies And Planning Keywords: New Jack City; textual analysis; neoliberalism; polity

Online: 25 March 2021 (15:09:38 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202011.0388.v1

Gamma-Divergence. An Introduction to New Divergence Family

Leonardo Riveaud, Mateos Diego, Pedro Walter Lamberti

Subject: Physical Sciences, Acoustics Keywords: Information Theory; Entropy; Divergence; Divergence families

Online: 13 November 2020 (15:45:32 CET)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202009.0348.v2

Quantitative Epigenetics: A New Avenue for Crop Improvement

Vijay Gahlaut, Gaurav Zinta, Vandana Jaiswal, Sanjay Kumar

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: DNA methylation; epialleles; epiRILs; epigenetics; Epigenome-Wide Association Studies.

Online: 26 September 2020 (08:08:27 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201809.0368.v4

C⁴ Space-Time.. A Window to New Physics?

Dimitris Mastoridis, Konstantinos Kalogirou

Subject: Physical Sciences, Mathematical Physics Keywords: extended space-time; complex space-time; unified theories; geometric unification; dark matter-energy; Cartan's principle of triality; extended general-special relativity

Online: 7 February 2020 (04:34:13 CET)

Show abstract| Download PDF| Share

We explore the possibility to form a physical theory in $C^4$. We argue that the expansion of our usual 4-d real space-time to a 4-d complex space-time, can serve us to describe geometrically electromagnetism and nuclear fields and unify it with gravity, in a different way that Kaluza-Klein theories do. Specifically, the electromagnetic field $A_\mu$, is included in the free geodesic equation of $C^4$. By embedding our usual 4-d real space-time in the symplectic 8-d real space-time (symplectic $R^8$ is algebraically isomorphic to $C^4$), we derive the usual geodesic equation of a charged particle in gravitational field, plus new information which is interpreted. Afterwards, we formulate and explore the extended special relativity and extended general relativity an $C^4$ or$R^8$. After embedding our usual 4-d space-time in $R^8$, two new phenomena rise naturally, that are interpreted as "dark matter" and "dark energy". A new cosmological model is presented, while the geometrical terms associated with "dark matter" and "dark energy" are investigated. Similarities, patterns and differences between "dark matter", "dark energy", ordinary matter and radiation are presented, where "dark energy" is a dynamic entity and "dark matter" reveal itself as a "mediator" betwen ordinary matter and "dark energy". Moreover, "dark matter" is deeply connected with "dark energy". Furthermore, the extended Hamilton-Jacobi equation of the extended space-time, is transformed naturally as an extended Klein-Gordon equation, in order to get in contact with quantum theories. By solving the Klein-Gordon equation analytically, we derive an eigenvalue for Higg's boson mass value at 125,173945 $Gev/c^{2}$. The extended Klein-Gordon equation, also connects Higg's boson (or vacuum) with Cosmology, due to the existence of our second "time" T (cosmological time), which serve us to connect quantum theories with Cosmology. Afterwards, in the general case, we explore the symmetries of the curved Hamilton-Jacobi equation locally, in order to investigate the consequences of a $C^4$ space-time in Standard Model. An extension to Standard Model is revealed, especially in the sector of strong nuclear field. The Stiefel manifold $SU(4)/SU(2)$ seems capable not only to describe the strong nuclear field but give us,as well, enough room to explore in the future, the possibility to explain quark confinment. Our extension, flavors firstly the unification of nuclear fields and afterwards the unification of nuclear fields with electromagnetic field. The desired grand unification, is achieved locally, through the symmetry group $GL(4,C)\simeq SO(4,4)\cap U(4)$ and we present a potential mechanism to reduce the existing particle numbers to just six. Afterwards,23 present the extended Dirac equation in $C^4$ space-time (Majorana-Weyl representation) plus a preliminary attempt to introduce a pure geometric structure for fermions. Finally, we consider a new geometric structure through n-linear forms in order to give geometric explanation for quantisation

Preprint CONCEPT PAPER | doi:10.20944/preprints201911.0372.v1

Phyllotaxis Turns over a New Leaf – A Review

Derek T Lamport, Li Tan, Michael Held, Marcia Kieliszewski

Subject: Biology And Life Sciences, Plant Sciences Keywords: arabinogalactan proteins; phyllotaxis; Hechtian Oscillator; calcium homeostasis; auxin

Online: 29 November 2019 (08:22:04 CET)

Show abstract| Download PDF| Supplementary Files| Share

Preprint TECHNICAL NOTE | doi:10.20944/preprints201901.0106.v1

Creating a new model in NS3 Network Simulator

Lesly Maygua-Marcillo, Luis Urquiza-Aguiar, Martha Paredes-Paredes

Subject: Engineering, Electrical And Electronic Engineering Keywords: error model; new model; NS-3; VANET; 802.11p

Online: 11 January 2019 (07:59:28 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201809.0113.v1

Photonic Hook Plasmons: A New Curved Surface Wave

Igor Minin

Subject: Physical Sciences, Optics And Photonics Keywords: Surface plasmon, Airy beam, photonic hook, curved wave, ﬂatland photonics

Online: 6 September 2018 (11:05:48 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints201806.0168.v1

New Therapies of Neovascular AMD – Beyond Anti VEGFs

Praveen Yerramothu

Subject: Medicine And Pharmacology, Ophthalmology Keywords: neovascular AMD; new therapies; anti-VEGFs; AMD signalling

Online: 12 June 2018 (06:26:56 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201805.0238.v2

New Advances in the Inspection of Flare Stacks

Carlos Martín Díaz de Espada, María Dolores Rubio Cintas

Subject: Engineering, Mechanical Engineering Keywords: flare stack; non-destructive testing; inspection; guy wires; drones

Online: 24 May 2018 (10:24:34 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201804.0025.v1

Six New Derivatives from Alternaria sp MCCC 3A00467

Tian-Hua Zhong, Xian-Ming Zeng, Xin-Hua Ma, Kai-Hui Sun, Hai-Tao Zhang, Shi-Biao Hong, Yong-Hong Zhang, Zhu-Hua Luo, Xu Wei

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: antitumor; Alternaria sp

Online: 2 April 2018 (11:27:27 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints201711.0092.v1

The Exact Evaluation of Some New Lattice Sums

John Zucker

Subject: Physical Sciences, Mathematical Physics Keywords: Jacobian q-series; closed form lattice sums

Online: 15 November 2017 (04:17:09 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202307.0894.v1

New Dimensions Regarding Demographic Behavior and Family Stability in Romania and Bihor County: A Comparative Analysis

Marcu Stasac, Marius I. Stupariu, Corina Florina Tatar, Ribana Linc, Liviu Bucur, Stelian Nistor

Subject: Environmental And Earth Sciences, Geography Keywords: demographic indicators; marriage rate; divorce rate; demographic potential; demographic behavior; Bihor county; Romania

Online: 13 July 2023 (07:32:14 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202307.0765.v1

Synthesis and Biological Evaluation of New Quinoline and Anthranilic Acid Derivatives as Potential Quorum-Sensing Inhibitors

Ivana Perković, Tanja Poljak, Kirsi Savijoki, Pekka Varmanen, Gordana Maravić-Vlahoviček, Maja Beus, Anja Kučević, Ivan Džajić, Zrinka Rajić

Subject: Medicine And Pharmacology, Pharmacy Keywords: 4-amino-7-chloroquinoline; 1,3,4-oxadiazole; anthranilic acid; synthesis; quorum sensing; anti-biofilm; P. aeruginosa; PQS

Online: 12 July 2023 (21:25:14 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202307.0708.v1

Comparative Analysis of Physicochemical Properties and Storability of a New Citrus Variety, Yellowball, and Its Parent

Dong-Shin Kim, Sung-man Jeong, Seong-Ho Jo, Saoraya Chanmuang, Sang Suk Kim, Suk Man Park, Su Hyun Yun, Seung-Gab Han, Jeong-Yong Cho, Inhae Kang, Hyun-Jin Kim

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Citrus; metabolomics; sensory evaluation; storability; Yellowball

Online: 11 July 2023 (10:18:17 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Preprint ARTICLE | doi:10.20944/preprints202306.1070.v1

5G and companion technologies as a boost in new business models for logistics and supply chain

Michela Apruzzese, Maria Elena Bruni, Stefano Musso, Guido Perboli

Subject: Business, Economics And Management, Business And Management Keywords: 5G networks; Logistics 4.0; Stakeholder assessment; Innovative technologies

Online: 15 June 2023 (10:06:19 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202205.0097.v1

Design of New Potent and Selective Thiophene-based KV1.3 Inhibitors and their Potential for Anticancer Activity

Špela Gubič, Louise Antonia Hendrickx, Xiaoyi Shi, Žan Toplak, Štefan Možina, Kenny M. Van Theemsche, Ernesto Lopes Pinheiro-Junior, Steve Peigneur, Alain J. Labro, Luis A. Pardo, Jan Tytgat, Tihomir Tomašič, Lucija Peterlin Mašič

Subject: Chemistry And Materials Science, Medicinal Chemistry Keywords: KV1.3; potassium ion channels; antiproliferative activity; apoptosis; anticancer drugs

Online: 9 May 2022 (03:35:09 CEST)

Show abstract| Download PDF| Share

Preprint REVIEW | doi:10.20944/preprints202105.0100.v1

Submerged Speleothems and Sea Level Reconstructions: A Global Overview and New Results from the Mediterranean Sea

Fabrizio Antonioli, Stefano Furlani, Paolo Montagna, Paolo Stocchi, Lucio Calcagnile, Gianluca Quarta, Jonatan Cecchinel, Valeria Lo Presti, Maurizio Gasparo Morticelli, Franco Foresta Martin, Valeria Vaccher

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: submerged speleothem; phreatic speleothem; sea level change; sea caves; vertical tectonic movements; Ustica; Favignana

Online: 6 May 2021 (15:11:18 CEST)

Show abstract| Download PDF| Share

Working Paper REVIEW

Diagnosis and Treatment of Bone Metastases in Breast Cancer: Radiotherapy, Local Approach, and Systemic Therapy in a Guide for Clinicians

Fabio Marazzi, Armando Orlandi, Stefania Manfrida, Valeria Masiello, Alba Di Leone, Mariangela Massaccesi, Francesca Moschella, Gianluca Franceschini, Emilio Bria, Maria Antonietta Gambacorta, Riccardo Masetti, Giampaolo Tortora, Vincenzo Valentini

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: bone metastasis; breast cancer; radiotherapy; diagnostic imaging; systemic therapies

Online: 20 August 2020 (04:25:31 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202403.1595.v1

Seasonal Effects of Wildfires on the Physical and Chemical Properties of Soil in Andean Grassland Ecosystems in Cusco, Peru: Pending Challenges

Melida Roman, Ricardo Zubieta, Yerson Ccanchi, Alejandra Martinez, Ysai Paucar, Sigrid Alvarez, Julio C. Loayza-Céspedes, Filomeno Ayala

Subject: Social Sciences, Geography, Planning And Development Keywords: Wildfire; Soil property; Fire prevention; Grassland; Andes

Online: 26 March 2024 (14:28:08 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202304.0267.v1

Reflecting on Leadership Experiences: The Positive and Negative Journeys of Women in Leadership

Shamma Al Naqbi

Subject: Social Sciences, Education Keywords: Leadership Experiences; Women in Leadership; Adolescent experiences; UAE; Women; Leadership development; Qualitative research; Semi-structured interviews; Document analysis; Diary writing; Family upbringing; Cultural values; Education; Societal expectations

Online: 12 April 2023 (09:41:03 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints201701.0125.v1

Equivalent Circulation Density Analysis of Geothermal Well by Coupling Temperature

Xiuhua Zheng, Chenyang Duan, Zheng Yan, Hongyu Ye, Zhiqing Wang, Bairu Xia

Subject: Engineering, Energy And Fuel Technology Keywords: wellbore pressure analysis; equivalent circulating density; geothermal well; wellbore temperature distribution; mathematical modeling

Online: 27 January 2017 (03:10:16 CET)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202404.1536.v1

The Effectiveness of Nutritional Interventions Implemented Through Lady Health Workers on the Reduction of Stunting in Children under 5 in Pakistan; The Difference‐in‐Difference Analysis

Khizar Ashraf, Tanvir M. Huda, Javeria Ikram, Shabina Ariff, Muhammad Sajid, Gul Nawaz Khan, Muhammad Umer, Imran Ahmed, Michael John Dibley, Sajid Bashir Soofi

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: nutrition; Pakistan; Stunting prevention; Lipid based nutrient supplements; programmatic review

Online: 23 April 2024 (17:51:57 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202406.0964.v1

Optimization of Energy Efficiency, Operation Costs and Carbon Footprint Using Pareto Analysis with New Generation Ro Membranes for Sea Water Desalination Plants

Nicolau Chirinza, Paulino Muguirrima, Federico A. Leon Zerpa, Alejandro Ramos-Martin, Sebastian Perez-Baez, Carlos Alberto Mendieta-Pino

Subject: Environmental And Earth Sciences, Water Science And Technology Keywords: Energy consumption; Reverse osmosis; Desalination plants; Pareto analysis

Online: 14 June 2024 (02:47:44 CEST)

Show abstract| Download PDF| Share

Preprint ARTICLE | doi:10.20944/preprints202410.0088.v1

Some Notes on the Gini Index and New Inequality Measures: The nth Gini Index

José Manuel Gavilan Ruiz, África Ruiz-Gándara, Francisco Javier Ortega Irizo, Luis Gonzalez Abril

Subject: Computer Science And Mathematics, Probability And Statistics Keywords: inequality measures; mean difference; order statistics; rank-dependent inequality measurement

Online: 2 October 2024 (07:10:37 CEST)

Show abstract| Download PDF| Supplementary Files| Share

Search Results

40413 articles found