ARTICLE
|
doi:10.20944/preprints202310.1965.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Farnesoid X receptor; gut microbiota; intestinal epithelial barrier; colon cancer; Klotho; fibroblast growth factor
Online: 30 October 2023 (16:39:45 CET)
COMMUNICATION
|
doi:10.20944/preprints201808.0534.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
long non coding RNA, whole exome sequencing, protein interaction, congenital pouch colon, microscale thermophoresis
Online: 30 August 2018 (15:30:35 CEST)
ARTICLE
|
doi:10.20944/preprints202409.0462.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Intracranial epidermoid cysts; rare cancers; whole-exome sequencing; targeted therapy
Online: 5 September 2024 (12:10:35 CEST)
REVIEW
|
doi:10.20944/preprints202308.1536.v4
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
multiregion sequencing; multisample sequencing; targeted cancer therapy; OVERCOME; macrophage magnetotaxis
Online: 5 February 2024 (13:52:59 CET)
ARTICLE
|
doi:10.20944/preprints202401.1862.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
breast cancer brain metastasis; targeted therapy;
Online: 26 January 2024 (10:13:50 CET)
REVIEW
|
doi:10.20944/preprints202401.1546.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Claudin; monoclonal antibodies; adenocarcinoma; targeted therapy; CAR-T cell therapy
Online: 22 January 2024 (10:02:04 CET)
REVIEW
|
doi:10.20944/preprints202311.1719.v1
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
Dravet Syndrome; developmental epileptic encephalopathy; genetics; targeted therapy; epilepsy syndrome
Online: 28 November 2023 (08:12:09 CET)
REVIEW
|
doi:10.20944/preprints202310.1097.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Nanobodies; respiratory viral infections; spray and aerosol particles; targeted delivery.
Online: 18 October 2023 (03:04:54 CEST)
ARTICLE
|
doi:10.20944/preprints202309.1864.v1
Subject:
Chemistry And Materials Science,
Food Chemistry
Keywords:
Dendrobium officinale; traditional processing; widely-targeted metabolic analysis; chemical ingredients
Online: 27 September 2023 (10:54:15 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0933.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
PDAC; precision medicine; gene alterations; molecular profiling; molecular targeted therapies
Online: 11 August 2023 (11:06:09 CEST)
REVIEW
|
doi:10.20944/preprints202307.1462.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
inflammatory breast cancer (IBC); review; immunotherapy; targeted therapy; tumor microenvironment
Online: 21 July 2023 (12:39:42 CEST)
REVIEW
|
doi:10.20944/preprints202305.0620.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
ALL; immunotherapy; antibody-drug conjugate; CAR-based therapies, targeted therapies
Online: 9 May 2023 (09:03:11 CEST)
REVIEW
|
doi:10.20944/preprints202304.0677.v1
Subject:
Biology And Life Sciences,
Other
Keywords:
Metabolomics; Simultaneous Quantitation and Discovery (SQUAD); Targeted Metabolomics; Untargeted Metabolomics
Online: 21 April 2023 (07:29:13 CEST)
ARTICLE
|
doi:10.20944/preprints202202.0222.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
hepatocellular carcinoma; lenvatinib; molecular targeted agents; complete response; CT value
Online: 18 February 2022 (04:05:18 CET)
ARTICLE
|
doi:10.20944/preprints202110.0196.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
star polymer; β-cyclodextrin; tumor-targeted; disulfide bond; theranostic nanoparticles
Online: 13 October 2021 (11:00:40 CEST)
REVIEW
|
doi:10.20944/preprints202105.0513.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Cell penetrating peptides; protein transduction domains; tumor imaging; targeted therapies.
Online: 21 May 2021 (09:44:48 CEST)
REVIEW
|
doi:10.20944/preprints202103.0095.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
doxorubicin; drug delivery; polymers; targeted therapy; anticancer treatment; controlled release
Online: 2 March 2021 (14:14:38 CET)
REVIEW
|
doi:10.20944/preprints202002.0382.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
metastatic breast cancer; targeted therapies; fibroblast growth factors receptors drugs
Online: 26 February 2020 (01:41:54 CET)
REVIEW
|
doi:10.20944/preprints201909.0026.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
antiandrogen; bisphosphonates; bone niche; immune system; osteoimmunology; RankL; targeted therapy
Online: 2 September 2019 (16:34:22 CEST)
ARTICLE
|
doi:10.20944/preprints202404.0571.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
fibrosis; tumor stroma; stroma to tumor ratio; pathology markers; colon cancer; adjuvant treatment; invasion front
Online: 8 April 2024 (14:35:27 CEST)
BRIEF REPORT
|
doi:10.20944/preprints202312.0774.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
DNA mismatch repair; MMR immunohistochemistry; colon cancer; endometrial carcinoma; microsatellite instability; MSI-H; MLH1/PMS2
Online: 12 December 2023 (05:05:34 CET)
ARTICLE
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
Micro Hand S surgical robot system; robot-assisted complete mesocolic excision; colon cancer; safety; feasibility
Online: 1 March 2020 (02:54:29 CET)
ARTICLE
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
Micro Hand S surgical robot system; robot-assisted complete mesocolic excision; colon cancer; safety; feasibility
Online: 28 February 2020 (16:10:11 CET)
REVIEW
|
doi:10.20944/preprints202408.0053.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
thrombotic disorders; targeted-antithrombotic approaches; nanothrombolysis; clot-penetrating drug; aging; fibrinolysis
Online: 2 August 2024 (03:57:37 CEST)
REVIEW
|
doi:10.20944/preprints202407.1752.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
conjunctival melanocytic intraepithelial lesions; conjunctival melanoma; ocular oncology, targeted therapy; immunotherapy
Online: 22 July 2024 (16:26:41 CEST)
REVIEW
|
doi:10.20944/preprints202404.0315.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
calcium carbonate; microparticles; microcapsules; core/shell structures; targeted delivery; anticancer treatment
Online: 3 April 2024 (16:07:30 CEST)
REVIEW
|
doi:10.20944/preprints202402.0634.v1
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
High Intensity Focused Ultrasound: HIFU: Non invasive surgery: Targeted Drug Delivery.
Online: 12 February 2024 (07:44:23 CET)
REVIEW
|
doi:10.20944/preprints202402.0117.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
nanomedicine; biomimicry; biomimetic nanoparticle; targeted drug delivery; homotypic targeting; nanoparticle coating
Online: 2 February 2024 (07:25:29 CET)
ARTICLE
|
doi:10.20944/preprints202312.2154.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
lung cancer; oligo-recurrence; driver mutation; local therapy; molecular targeted therapy
Online: 28 December 2023 (10:23:13 CET)
DATA DESCRIPTOR
|
doi:10.20944/preprints202310.0082.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
Precision Metagenomics; Next Generation Sequencing (NGS), Respiratory infections, Microbiome, Targeted Sequencing
Online: 3 October 2023 (03:06:42 CEST)
REVIEW
|
doi:10.20944/preprints202308.1346.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
Immune-mediated bowel diseases; intestinal parasites; microbiome; homeostasis; targeted therapeutic strategies.
Online: 18 August 2023 (09:21:43 CEST)
REVIEW
|
doi:10.20944/preprints202307.1695.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
hepatocellular carcinoma; EGFR/PI3K/AKT/mTOR signaling; animal models; Targeted Therapy
Online: 26 July 2023 (10:07:16 CEST)
REVIEW
|
doi:10.20944/preprints202109.0453.v3
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
BNCT; targeted therapy; biological dosimetry; boron imaging; personalized oncology; personalized medicine
Online: 16 May 2022 (15:22:13 CEST)
REVIEW
|
doi:10.20944/preprints202111.0504.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
NSCLC 1; KRAS G12C mutation 2; targeted therapy 3; immunotherapy 4
Online: 26 November 2021 (11:34:27 CET)
REVIEW
|
doi:10.20944/preprints202110.0013.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
uveal melanoma; tumorigenesis; molecular classification; targeted therapy; immune checkpoint; tumor heterogeneity
Online: 1 October 2021 (11:54:23 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0772.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Immune checkpoint inhibitors; immune-related endocrine dysfunction; hypothyroidism; targeted therapy; malignancy
Online: 31 May 2021 (12:49:40 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0671.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Folate-targeted nanoparticles; BSA/Alginate nanocarriers; paclitaxel; cellular uptake; cell viability.
Online: 27 May 2021 (13:55:13 CEST)
REVIEW
|
doi:10.20944/preprints201806.0105.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
fibroblast growth factor; fibroblast growth factor receptor; targeted treatments; breast cancer
Online: 7 June 2018 (07:50:30 CEST)
ARTICLE
|
doi:10.20944/preprints201805.0467.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Tspo; prostate cancer; stomach cancer; colon cancer; liver cancer; lung cancer; kidney cancer; breast cancer; brain cancer
Online: 31 May 2018 (10:59:31 CEST)
ARTICLE
|
doi:10.20944/preprints202409.0907.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
PIM kinases; estrogen receptor α; luminal A breast cancer; targeted therapy resistance
Online: 11 September 2024 (16:23:00 CEST)
ARTICLE
|
doi:10.20944/preprints202408.0697.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
SPECT; de novo protein design; technetium; targeted delivery; cancer; in vivo imaging
Online: 9 August 2024 (10:23:29 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0581.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Consanguinity; gene panel; Inherited retinal diseases; retinal dystrophy; targeted next generation sequencing
Online: 11 June 2024 (15:01:06 CEST)
ARTICLE
|
doi:10.20944/preprints202404.1167.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Wilms’ tumor; Chemotherapy resistance; Biomarkers; Somatic mutation; Targeted therapy; Cancer-driver mutation
Online: 17 April 2024 (15:03:01 CEST)
REVIEW
|
doi:10.20944/preprints202402.0637.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
TPD; PROTAC; molecular glue degrader; heterobifunctional degrader; Ubiquitin; proteasome; targeted protein degradation
Online: 12 February 2024 (07:43:06 CET)
ARTICLE
|
doi:10.20944/preprints202401.1267.v1
Subject:
Engineering,
Bioengineering
Keywords:
Functional electrical stimulation; Current steering; Finite Element Modeling; Electrode arrays; Targeted activation
Online: 17 January 2024 (04:26:52 CET)
REVIEW
|
doi:10.20944/preprints202401.0437.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
HER2 positive; Breast Cancer; Systemic De-Escalation; Chemo-free therapy; Targeted Therapy
Online: 5 January 2024 (06:47:05 CET)
REVIEW
|
doi:10.20944/preprints202306.1788.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Meningioma; Cabozantinib; VEGF; Targeted treatment Cabozantinib; METs; VEGFR2; Inhibitors; Angiogen-esis; Oncology
Online: 26 June 2023 (10:57:00 CEST)
ARTICLE
|
doi:10.20944/preprints202301.0512.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
micronutrient deficiencies; rational food design; adolescents; biscuits; texture; chickpea flour; targeted nutrition
Online: 28 January 2023 (03:06:52 CET)
REVIEW
|
doi:10.20944/preprints202202.0052.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cervical cancer; endometrial cancer; ovarian cancer; 2021 update; novel targeted therapies; immunotherapy
Online: 3 February 2022 (13:02:11 CET)
ARTICLE
|
doi:10.20944/preprints202105.0333.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
genome editing; CRISPR; protoplast; , targeted mutagenesis; TREX2; construct validation; transi-ent expression
Online: 14 May 2021 (13:44:26 CEST)
ARTICLE
Subject:
Environmental And Earth Sciences,
Sustainable Science And Technology
Keywords:
Straw Hat University; Farmer's Professor; Rural Transformation; Targeted poverty alleviation in China
Online: 7 April 2021 (17:40:08 CEST)
REVIEW
|
doi:10.20944/preprints202007.0523.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
discovery proteomics; targeted proteomics; mass spectrometry; fish allergens; crustacean allergens; mollusk allergens
Online: 22 July 2020 (11:23:40 CEST)
REVIEW
|
doi:10.20944/preprints201909.0140.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
hepatocellular carcinoma; immune checkpoint inhibitors; HCC; pembrolizumab; nivolumab; immune microenvironment; targeted therapies
Online: 14 September 2019 (18:37:29 CEST)
REVIEW
|
doi:10.20944/preprints201904.0127.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
PTEN; PI3K; cancer predisposition syndromes; targeted therapies; mouse models of human cancer
Online: 10 April 2019 (10:37:43 CEST)
ARTICLE
|
doi:10.20944/preprints201807.0459.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
Superparamagnetic iron oxide; Magnetic resonance imaging; Solid lipid nanoparticles; Galactose; Liver-targeted
Online: 24 July 2018 (14:01:51 CEST)
REVIEW
|
doi:10.20944/preprints202401.0426.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
PDAC; molecular alterations; oncogenic pathways; targeted therapy; preclinical; clinical; combinational therapy; clinical trials
Online: 5 January 2024 (06:28:11 CET)
ARTICLE
|
doi:10.20944/preprints202312.0054.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Ex Vivo Resistance Platform; CAF-mediated Resistance; Combinations of cytotoxic and targeted drugs
Online: 1 December 2023 (07:57:41 CET)
REVIEW
|
doi:10.20944/preprints202307.0552.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cancer chemotherapy; transmembrane receptors; EGFR; targeted protein degradation; furfuryl-quinolin-triazole-thiol chemicals
Online: 10 July 2023 (07:23:13 CEST)
ARTICLE
|
doi:10.20944/preprints202307.0161.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Non-small cell lung cancer; Targeted Gene Therapy; Immune Checkpoint Inhibitors; Machine Learning
Online: 4 July 2023 (07:57:03 CEST)
ARTICLE
|
doi:10.20944/preprints202305.0400.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
transcriptionally targeted oncolytic adenovirus; gynecologic cancer; human samples; cytokines; ovarian cancer; tumor stroma
Online: 6 May 2023 (09:25:49 CEST)
ARTICLE
|
doi:10.20944/preprints202302.0343.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
targeted alpha therapy; alpha-emitter; thorium-226; uranium-230; isotope generator; extraction chromatography
Online: 20 February 2023 (14:17:58 CET)
REVIEW
|
doi:10.20944/preprints202210.0362.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
gut microbiome; time-restricted feeding; intermittent fasting; targeted approach; hormonal signaling; metabolic regulators
Online: 24 October 2022 (12:00:48 CEST)
REVIEW
|
doi:10.20944/preprints202206.0160.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
breast cancer; HER2-positive; estrogen receptor positive; triple-positive; HER2-targeted therapy; immunotherapy
Online: 10 June 2022 (11:03:05 CEST)
ARTICLE
|
doi:10.20944/preprints202111.0257.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
metastatic melanoma; targeted therapy; immune checkpoint inhibitor therapy; survival; statutory health insurance data
Online: 15 November 2021 (11:50:07 CET)
ARTICLE
|
doi:10.20944/preprints202109.0289.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
BRD9; Prostate Cancer; SWI/SNF; Survival; pathways; signal transduction; human cohorts; targeted therapy
Online: 16 September 2021 (13:51:57 CEST)
ARTICLE
|
doi:10.20944/preprints202404.0092.v3
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
p53 loss; KRAS mutation; SLC7A11; SLC38A5; ferroptosis; macropinocytosis; antioxidant machinery; lipid peroxidation; niclosamide; colon cancer
Online: 7 June 2024 (02:47:47 CEST)
ARTICLE
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Oleuropein; colon cancer; activated macrophages; chronic inflammation; inducible nitric oxide synthetase (iNOS); cyclooxygenase-2 (COX-2); nitric oxide (NO)
Online: 2 August 2021 (12:04:58 CEST)
ARTICLE
|
doi:10.20944/preprints202004.0198.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
mathematical modelling; peristalsis; smoothed particle hydrodynamics (SPH); fluid dynamics; large intestine; colonl proximal colon; fluid-structure interactions; drug delivery
Online: 12 April 2020 (15:57:17 CEST)
ARTICLE
|
doi:10.20944/preprints202310.1260.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Protons; X-rays; oral squamous cell carcinoma; extracellular vesicles; non-targeted effects of radiation
Online: 19 October 2023 (09:59:48 CEST)
ARTICLE
|
doi:10.20944/preprints202307.0262.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
DCL ligand; iodine radioisotopes; radiolabeled pharmaceuticals; targeted delivery; prostatic specific membrane antigen; prostate cancer
Online: 5 July 2023 (04:43:46 CEST)
ARTICLE
|
doi:10.20944/preprints202303.0315.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Type I nitroreductase; NfsB; Crystal structure; Prodrug; Metronidazole; Targeted cellular ablation; Tinidazole; CB1954; Dinitrotoluene
Online: 17 March 2023 (03:22:59 CET)
ARTICLE
|
doi:10.20944/preprints202212.0214.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Breast; Targeted Radiotherapy; Lung injury; Heart injuries; Health-Related Quality Of Life; Irradiation toxicity.
Online: 13 December 2022 (01:17:52 CET)
COMMUNICATION
|
doi:10.20944/preprints202112.0420.v3
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
Non-targeted methods; method validation; food fraud; food authenticity; mass spectrometry; spectroscopy; NGS; NMR
Online: 23 May 2022 (11:10:00 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0724.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
TNBC; dasatinib; poly(styrene-co-maleic acid) micelles; nanoformulation; metabolism; EPR; nanomedicine; targeted therapy.
Online: 27 April 2021 (13:56:12 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Obstetrics And Gynaecology
Keywords:
HBOC; statewide random sampling; cancer survivorship; targeted intervention; tailored intervention; black participants; family recruitment
Online: 5 September 2019 (16:16:34 CEST)
REVIEW
|
doi:10.20944/preprints201902.0245.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cyclin-dependent kinases; cyclin-dependent kinase 4 and 6 inhibitors; targeted therapies; breast cancer
Online: 27 February 2019 (04:48:54 CET)
ARTICLE
|
doi:10.20944/preprints201609.0024.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
neurofibromatosis type 1; congenital pseudarthrosis of the tibia; whole-exome sequencing; targeted sequencing; BCOR
Online: 7 September 2016 (11:19:00 CEST)
ARTICLE
|
doi:10.20944/preprints202309.2064.v1
Subject:
Computer Science And Mathematics,
Security Systems
Keywords:
adversarial attacks; artificial intelligence; machine learning; defense mechanisms; system integrity; model vulnerabilities; advanced attack techniques; Fast Gradient Sign Method (FGSM); Carlini and Wagner Attack (C&W); targeted attacks; non-targeted attacks; blackbox attacks
Online: 29 September 2023 (08:42:10 CEST)
REVIEW
|
doi:10.20944/preprints202409.0327.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Breast cancer; HER2; Trastuzumab; Pertuzumab; De-escalation; Personalized medicine; Targeted therapies; Adjuvant therapies; Neoadjuvant therapies
Online: 5 September 2024 (04:54:49 CEST)
ARTICLE
|
doi:10.20944/preprints202408.0098.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Comprehensive Genomic Profiling (CGP); Next Generation Sequencing (NGS); Artificial Intelligence; Cancer Genomics; Targeted gene sequencing
Online: 4 August 2024 (16:28:04 CEST)
REVIEW
|
doi:10.20944/preprints202403.1011.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
retinoblastoma; RB1; E2F; Targeted Therapy; Therapeutic Vulnerabilities; Spliceosome; Cell Cycle; Epigenetic Regulators; Ubiquitin-Proteasome Pathway
Online: 18 March 2024 (10:29:38 CET)
ARTICLE
|
doi:10.20944/preprints202401.0334.v1
Subject:
Public Health And Healthcare,
Other
Keywords:
recurrent ovarian cancer; platinum-sensitive relapse; platinum-resistant relapse; platinum refractory relapse; targeted therapy; chemotherapy
Online: 4 January 2024 (04:18:09 CET)
CASE REPORT
|
doi:10.20944/preprints202306.1950.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
inflammatory breast carcinoma; targeted biological therapy; HER2 overexpression; multidisciplinary treatment; aggressive cancer management; systemic chemotherapy
Online: 28 June 2023 (07:12:56 CEST)
REVIEW
|
doi:10.20944/preprints202210.0450.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Tumor microenvironment; stromal cells; immune cells; ECM; cancer hallmarks; hypoxia; exosomes; drug resistance; targeted therapy
Online: 28 October 2022 (09:57:34 CEST)
REVIEW
|
doi:10.20944/preprints202208.0220.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Molecular switches; oncolytic vectors; patient-specific ubiquitous mutations; targeted therapy; multi-region sequencing; molecular biology
Online: 11 August 2022 (11:50:12 CEST)
ARTICLE
|
doi:10.20944/preprints202204.0137.v1
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
Taihe silky fowl; metabolic components; un-targeted metabolome; breed and feed; biosynthesis of amino acids
Online: 15 April 2022 (05:47:06 CEST)
ARTICLE
|
doi:10.20944/preprints202109.0300.v1
Subject:
Computer Science And Mathematics,
Applied Mathematics
Keywords:
CAR T; Targeted Radionuclide Therapy; TRT; Mathematical Model; Multiple Myeloma; Immunotherapy; Daratumumab; CS1; Combination Therapy
Online: 17 September 2021 (09:32:33 CEST)
ARTICLE
|
doi:10.20944/preprints202106.0638.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
pancreatic ductal adenocarcinoma; targeted therapies; therapeutic resistance; tumor microenvironment; desmoplasia; collagen; collagenase; attenuated Salmonella typhimurium
Online: 28 June 2021 (10:36:31 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0692.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
RACK1; HIV-1; IRES; Hepatitis C; HCV; AZT; HTA; Host-targeted antiviral; HEK293T; SD29-14
Online: 26 April 2021 (20:35:00 CEST)
COMMENTARY
|
doi:10.3390/sci2030070
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
small molecule inhibitor; personalized medicine; precision medicine; oncology; targeted therapy; drug delivery; drug screening; chemotherapy
Online: 8 September 2020 (00:00:00 CEST)
REVIEW
|
doi:10.20944/preprints202407.2048.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
plant-derived exosomes; exosomes isolation; exosomes biogenesis; exosomes characterization; exosomes engineering; targeted therapies; cross kingdom regulations
Online: 26 July 2024 (04:31:34 CEST)
REVIEW
|
doi:10.20944/preprints202312.2256.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
acute myeloid leukemia; TP53 mutations; TP53-mutated acute myeloid leukemia; novel targeted AML therapies; AML immunotherapies
Online: 29 December 2023 (05:27:17 CET)
REVIEW
|
doi:10.20944/preprints202311.0094.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Casein Kinase II; Musculoskeletal; Osteoarthritis; Osteoporosis; CX-4945; CIBG-300; Cell Signaling; Drug Development; Targeted therapy
Online: 1 November 2023 (13:18:42 CET)
REVIEW
|
doi:10.20944/preprints202103.0143.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
antioxidants; alcohol metabolism; hepatoprotective; anti-ALD; mitochondrial dysfunction; mitochondria-targeted; oxidative stress; and cytochrome P450 2E1
Online: 4 March 2021 (09:13:05 CET)
REVIEW
|
doi:10.20944/preprints201811.0143.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
clear cell renal cell carcinoma; tumor evolution; tumor ecology; intratumor heterogeneity; multisite tumor sampling; targeted therapy
Online: 6 November 2018 (13:30:54 CET)
ARTICLE
|
doi:10.20944/preprints201804.0307.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
gastric cancer; ramucirumab; paclitaxel; second line therapy; vascular endothelial growth factor receptor 2; targeted therapy; nutrition
Online: 24 April 2018 (06:01:56 CEST)
REVIEW
|
doi:10.20944/preprints202408.0744.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
Peripheral T-cell lymphoma; Histone deacetylase (HDAC); HDAC inhibitor (HDACi); targeted therapy; epigenetic; DNA mutation; TET2; DNMT3A
Online: 12 August 2024 (05:07:04 CEST)
REVIEW
|
doi:10.20944/preprints202407.1712.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
facioscapulohumeral muscular dystrophy (FSHD); DUX4; antisense oligonucleotides; RNAi; CRISPR; DNA aptamers; DNA decoys; targeted therapy; genetic therapy
Online: 22 July 2024 (11:53:34 CEST)
ARTICLE
|
doi:10.20944/preprints202312.1002.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
intranasal spray; drug delivery; respiratory transport modeling; respiratory diseases; upper airway physiology; targeted nasal therapy; gentlemistTM technology
Online: 13 December 2023 (13:05:13 CET)
ARTICLE
|
doi:10.20944/preprints202105.0546.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
triple negative breast cancer; Pembrolizumab; Atezolizumab; chemotherapy; anti-PD-L1; biomarkers; targeted therapies; development of novel drugs
Online: 24 May 2021 (09:23:50 CEST)