ARTICLE
|
doi:10.20944/preprints202405.1984.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
HVEM; CD160; clear cell renal cell carcinoma (ccRCC); single nucleotide gene polymorphism (SNP); immunological checkpoint; disease risk; overall survival
Online: 30 May 2024 (09:28:36 CEST)
ARTICLE
|
doi:10.20944/preprints202405.0209.v1
Subject:
Medicine And Pharmacology,
Orthopedics And Sports Medicine
Keywords:
infantile tibia vara; Blount’ s disease; varus knee; tibia; child; opening wedge; high tibial osteoto-my; osteotomy; allograft
Online: 6 May 2024 (07:58:22 CEST)
ARTICLE
|
doi:10.20944/preprints202403.0465.v1
Subject:
Computer Science And Mathematics,
Applied Mathematics
Keywords:
penalized regression; Akaike’ s Information Criterion; high-dimensional data; stability; overall weighted coefficients; Alzheimer’ s disease; SNP
Online: 8 March 2024 (04:29:51 CET)
REVIEW
|
doi:10.20944/preprints202401.2149.v2
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
Parkinson’ s disease, Dopamine, Acetylcholine, Nicotine, Nicotinic receptors, Microglia, Astroglia, Oligodendrocyte, NG2 Cells, Alpha-Synuclein, Toll-Like receptors, Neuroinflammation, Neuroprotection
Online: 4 March 2024 (09:56:14 CET)
ARTICLE
|
doi:10.20944/preprints202401.1555.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
Alzheimer's disease; Melatonin; Melatonin analogue; icvAβ 1-42; pTAU; MT receptors; ERK; CREB
Online: 22 January 2024 (05:45:34 CET)
ARTICLE
|
doi:10.20944/preprints202401.0326.v1
Subject:
Medicine And Pharmacology,
Obstetrics And Gynaecology
Keywords:
Rheumatic disease in pregnancy; Fetal atrioventricular block; Homemonitoring; anti-Ro/anti-La antibodies; Lupus erythematodes; Sjö gren Syndrom
Online: 4 January 2024 (15:18:00 CET)
REVIEW
|
doi:10.20944/preprints202312.2132.v1
Subject:
Biology And Life Sciences,
Agricultural Science And Agronomy
Keywords:
Colletotrichum lupini; Lupinus spp; disease management; early molecular pathogen detection; infection mechanisms; molecular regulatory pathways; prophylaxis; genetic resistance; breeding
Online: 28 December 2023 (10:17:45 CET)
ARTICLE
|
doi:10.20944/preprints202312.1632.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Transfusion-Dependent Thalassemia; Health-Related Quality of Life; Patient Reported Outcomes; disease-specific TranQol questionnaire; Healthcare policy; Thalassemia Unfastructure
Online: 21 December 2023 (13:41:48 CET)
ARTICLE
|
doi:10.20944/preprints202311.1601.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
celiac disease; glutenase; gliadinase; gluten-free diet; gluten-derived pro-immunogenic peptides; oral enzyme therapy; enzyme active-site modification.
Online: 25 November 2023 (14:34:58 CET)
ARTICLE
|
doi:10.20944/preprints202311.0768.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
Cardiovascular diseases (CVDs); non-communicable diseases (NCDs); disease self-management; digital health application; randomized controlled trial; multiple behavior change
Online: 13 November 2023 (08:49:15 CET)
REVIEW
|
doi:10.20944/preprints202310.2045.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
Flavivirus; Eye; West Nile Virus; Dengue fever Virus; Yellow Fever; Zika virus; Japanese Encephalitis Virus; Kyasanur Forest Disease Virus
Online: 1 November 2023 (03:05:45 CET)
REVIEW
|
doi:10.20944/preprints202310.1603.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
chronic traumatic encephalopathy (CTE); Alzheimer’s disease (AD); traumatic encephalopathy syndrome (TES); traumatic brain injury (TBI); repetitive head impacts (RHI)
Online: 25 October 2023 (08:57:48 CEST)
REVIEW
|
doi:10.20944/preprints202310.0576.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
methylglyoxal; glyoxalase; advanced glycation end products; MG-H1, metabolic syndrome; insulin resistance, diabetes mellitus; cardiovascular disease; metformin; methylglyoxal scavengers
Online: 10 October 2023 (12:31:23 CEST)
REVIEW
|
doi:10.20944/preprints202309.0210.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
Brain-derived neurotrophic factor (BDNF); Alzheimer’s disease; exercise; osteocalcin; FNDC5/irisin; lactate; APP processing; dementia; cognition; learning and memory
Online: 5 September 2023 (03:45:49 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0889.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
phorbol 12-myristate 13-acetate (PMA); R406W mutant tau; Frontotemporal lobar degeneration (FTLD); Alzheimer’s disease (AD); neurodegenerative diseases (NDDs)
Online: 11 August 2023 (09:00:28 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0249.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
heart; ischemia; reperfusion; electrocardiography; ultra-high resolution electrocardiography; power spectral density; ischemic heart disease; subclinical atherosclerosis; sensitivity; risk stratification
Online: 3 August 2023 (05:17:42 CEST)
REVIEW
|
doi:10.20944/preprints202306.2123.v1
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
sarcopenia; frailty; comorbidity; diabetes; chronic kidney disease (CKD); heart failure; dementia; vitamin D; oral nutritional supplement (ONS); elderly people
Online: 29 June 2023 (13:14:19 CEST)
REVIEW
|
doi:10.20944/preprints202306.2095.v1
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
sarcopenia; frailty; comorbidity; diabetes; chronic kidney disease (CKD); heart failure; dementia; vitamin D; oral nutritional supplement (ONS); elderly people
Online: 29 June 2023 (11:05:54 CEST)
REVIEW
|
doi:10.20944/preprints202306.1651.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Proteomics; ELISA; mass spectrometry; Liquid chromatography; Luminex; Uniprot; Rosseta comment; Mascot; allergy respiratory disease; inflammation type 2; diapedesis; epitopo
Online: 23 June 2023 (09:46:31 CEST)
ARTICLE
|
doi:10.20944/preprints202306.0341.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
tuberculosis infection; tuberculosis disease; tuberculosis preventive treatment; latent tuberculosis infection; diabetes mellitus; adverse events; isoniazid; rifampicin; randomized controlled trial
Online: 5 June 2023 (15:01:24 CEST)
REVIEW
|
doi:10.20944/preprints202305.2254.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
autosomal dominant polycystic kidney disease; total kidney volume; cyst volume; non-cystic tissue; magnetic resonance imaging; segmentation; artificial intelligence
Online: 31 May 2023 (13:18:14 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1365.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
coronary artery disease; plasma lipids; carotid intima-media thickness; pharmacogenetics; personalized medicine; single nucleotide polymorphisms; lipid-lowering therapy; rosuvastatin.
Online: 19 May 2023 (03:26:56 CEST)
ARTICLE
|
doi:10.20944/preprints202304.1063.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
empagliflozin; vascular calcification; AMP-activated protein kinase; nuclear factor erythroid-2-related factor; heme oxygenase 1; chronic kidney disease
Online: 27 April 2023 (09:35:25 CEST)
ARTICLE
|
doi:10.20944/preprints202304.0384.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
pulmonary organoids; induced pluripotent stem cells (iPSCs); anterior foregut endoderm; mesoderm; alveoli epithelial cells; SARS-Cov2; iPSC disease modelling
Online: 17 April 2023 (03:33:39 CEST)
ARTICLE
|
doi:10.20944/preprints202212.0072.v1
Subject:
Computer Science And Mathematics,
Probability And Statistics
Keywords:
beta prime distribution; Weibull distribution; mixture representations; information generating function; entropies; order statistics; Monte Carlo simulation; blood cancer disease
Online: 5 December 2022 (09:47:54 CET)
ARTICLE
|
doi:10.20944/preprints202211.0285.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
Coronavirus disease 2019; interobserver agreement; interrater reliability; lung ultrasound; point-of-care ultrasound; reliability; severe acute respiratory syndrome; ultrasound
Online: 15 November 2022 (09:57:17 CET)
ARTICLE
|
doi:10.20944/preprints202210.0100.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
screening after pulmonary embolism; chronic thromboembolic pulmonary disease; chronic thromboembolic pulmonary hypertension; diagnostic work-up of post-pulmonary syndrome
Online: 9 October 2022 (02:09:20 CEST)
REVIEW
|
doi:10.20944/preprints202205.0166.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Antimicrobial Peptides (AMPs); Alzheimer’s Disease (AD); infectious hypothesis; beta-amyloid (Ab); lactoferrin; defensins; cystatins; thymosin β4; histatin 1; statherin
Online: 12 May 2022 (09:40:33 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0246.v1
Subject:
Biology And Life Sciences,
Agricultural Science And Agronomy
Keywords:
agriculture 4.0; chlorophyll; early diagnosis; fungal tree pathogens; mycology; plant disease; plant pathology; smart viticulture; vegetation indices; wine grapes
Online: 11 May 2021 (14:21:25 CEST)
REVIEW
|
doi:10.20944/preprints202103.0219.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Alzheimer’s disease; blood-brain barrier; endothelial cell; laminin; multiple sclerosis; pericyte; perivascular macrophage; sonic hedgehog; vascular smooth muscle cell
Online: 8 March 2021 (13:35:25 CET)
REVIEW
|
doi:10.20944/preprints202102.0193.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
mild cognitive impairment (MCI); mild dementia; Alzheimer’s disease; Ginkgo biloba (EGb761®); Tebonin; anti-dementia drugs; randomized controlled trials
Online: 8 February 2021 (11:37:05 CET)
ARTICLE
|
doi:10.20944/preprints202102.0069.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
extracellular vesicles (EVs); urinary extracellular vesicles (uEVs); exosomes; biomarkers; liquid biopsy; cirrhosis; fibrosis; hepatocarcinoma (HCC); alcoholic liver disease (ALD).
Online: 1 February 2021 (18:15:22 CET)
REVIEW
|
doi:10.20944/preprints202101.0625.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Alzheimer’s disease; dementia, beta-amyloid; germ theory; drug development; clinical trials; herpes; spirochetes; Chlamydia pneumoniae; Porphyromonas gingivalis; toxoplasma; mycobacteria
Online: 29 January 2021 (13:57:18 CET)
REVIEW
|
doi:10.20944/preprints202012.0578.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Unfolded protein response; Endoplasmic reticulum stress; Glucose-regulated protein 78 kD; Inflammatory Bowel Diseases; Crohn’s disease; Fibrosis; Wound healing
Online: 12 January 2021 (17:03:10 CET)
ARTICLE
|
doi:10.20944/preprints202010.0200.v1
Subject:
Medicine And Pharmacology,
Other
Keywords:
digital reference object; blood-brain barrier permeability; DCE-MRI; Spatio-temporal imaging artefacts; endothelial dysfunction; cerebral small vessel disease
Online: 9 October 2020 (12:44:33 CEST)
ARTICLE
|
doi:10.20944/preprints202010.0030.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Amazonian region; ZIKV in pregnancy; Exanthematic disease in pregnancy; Torch syndrome; Abortion; Stillbirth; Mycrocephaly; Preterm delivery; Low birth weight
Online: 2 October 2020 (08:47:53 CEST)
REVIEW
|
doi:10.20944/preprints202009.0076.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
severe acute respiratory syndrome coronavirus 2; SARS-CoV-2; coronavirus disease 2019; COVID-19; viral infection; virus-host interaction
Online: 4 September 2020 (03:19:43 CEST)
ARTICLE
|
doi:10.20944/preprints202007.0596.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
COVID-19; SARS-CoV-2; immunity; T cells; IL-6; GGT; hepatopathy; biliary lesion; acute kidney injury; liver disease
Online: 24 July 2020 (14:40:42 CEST)
REVIEW
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
acute coronary syndromes; myocardial infarction; STEMI; Covid-19, infectious disease; respiratory infections; pathophysiology; percutaneous coronary intervention; thrombolysis; drug treatment
Online: 7 May 2020 (12:49:39 CEST)
ARTICLE
|
doi:10.20944/preprints202002.0452.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
neurodegeneration; Parkinson's disease; essential tremor; Deep Brain stimulation; Levodopa; Virtual Reality; Oculus Rift; Medical Virtual Reality; Tremor stabilization; Equalizers
Online: 29 February 2020 (03:56:19 CET)
ARTICLE
|
doi:10.20944/preprints201910.0185.v1
Subject:
Medicine And Pharmacology,
Dietetics And Nutrition
Keywords:
sodium; potassium; nutrition; diet; urine spot; food frequency questionnaire; cardiovascular disease; childhood cancer survivors; Swiss childhood cancer registry; Europe
Online: 16 October 2019 (10:25:07 CEST)
ARTICLE
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
D-Glutamate and D-Glutamate racemase; Mitochondria; evolutionary approach; gut microbiota; Amyotrophic Lateral Sclerosis (ALS); Motor neurone disease (MND)
Online: 30 September 2019 (03:13:27 CEST)
REVIEW
|
doi:10.20944/preprints201702.0020.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
alpha-synuclein; Parkinsons disease; dementia with Lewy bodies; multiple system atrophy; tunelling nanotube; glymphatic system; cell-to-cell spread
Online: 7 February 2017 (03:24:21 CET)
ARTICLE
|
doi:10.20944/preprints202208.0176.v1
Subject:
Social Sciences,
Psychology
Keywords:
psychological distress/anxiety/depression; dementia; Alzheimer’s disease; Parkinson’s disease; short form of the Depression Anxiety Stress Scale 21; Depression Anxiety Stress Scale 8-items; factor structure; psychometric properties; structural validity; validation; measurement invariance; old age/elders/elderly; informal; family caregivers; spouse; adult children
Online: 9 August 2022 (08:44:11 CEST)
REVIEW
|
doi:10.20944/preprints202408.1730.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Serotonin; Gut-Brain Interaction; Biomarker; Mood; Irritable Bowel Syndrome (IBS); Inflammatory Bowel Disease (IBD); Functional Dyspepsia (FD); Cancer; Gut Homeostasis
Online: 23 August 2024 (18:50:30 CEST)
REVIEW
|
doi:10.20944/preprints202408.0674.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
Myocardial Infarction with Non-Obstructive Coronary Arteries; thromboembolism; coronary artery spasm; spontaneous coronary artery dissection; coronary microvascular disease; diagnosis; prognosis
Online: 9 August 2024 (12:14:30 CEST)
ARTICLE
|
doi:10.20944/preprints202407.2420.v1
Subject:
Medicine And Pharmacology,
Complementary And Alternative Medicine
Keywords:
Neuroinflammation; Alzheimer’ s disease; pomegranate (Punica granatum L); oxidative stress; microglia; amyloid-beta; phospho-Tau-181; ellagic acid; punicalagin
Online: 30 July 2024 (08:07:35 CEST)
ARTICLE
|
doi:10.20944/preprints202406.1467.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
Malnutrition; Mini Nutritional Assessment (MNA); Chronic Obstructive Pulmonary Disease (COPD); acute exacerbation of COPD (AECOPD); Quality of Life; Frailty; Multimorbidity
Online: 21 June 2024 (02:48:01 CEST)
ARTICLE
|
doi:10.20944/preprints202404.1820.v1
Subject:
Medicine And Pharmacology,
Otolaryngology
Keywords:
Mé niè re´ s disease; stroke; vertebrobasilar; cardiovascular; risk factors; microcirculation; inner ear; posterior circulation; POCI; cerebral
Online: 28 April 2024 (05:37:06 CEST)
REVIEW
|
doi:10.20944/preprints202404.0917.v1
Subject:
Public Health And Healthcare,
Other
Keywords:
Diabetes mellitus; periodontitis; type 1 diabetes mellitus; molecular mechanisms; cellular mechanisms; oral microbiota; host immune response; oxidative stress; periodontal disease
Online: 15 April 2024 (07:26:10 CEST)
REVIEW
|
doi:10.20944/preprints202401.2158.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Dystrophin; mitochondria; inflammation; reactive oxygen species; glucocorticoids; cardiomyopathy; neuromuscular disease; therapeutic target; treatment; stress response; ATP; respiration; calcium; ion homeostasis
Online: 31 January 2024 (07:21:25 CET)
ARTICLE
|
doi:10.20944/preprints202312.1980.v1
Subject:
Medicine And Pharmacology,
Dietetics And Nutrition
Keywords:
cornelian cherry; Cornus mas L.; iridoid; anthocyanin; transcription factor; ATP-binding cassette transporter; adipokine; common carotid artery; atherosclerosis; cardiovascular disease
Online: 26 December 2023 (11:27:47 CET)
ARTICLE
|
doi:10.20944/preprints202312.1674.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
locally advanced cervical cancer; concurrent chemoradiotherapy; adjuvant surgery; local control; high cervical cancer morbidity; residual disease; cervical cancer in Romania
Online: 21 December 2023 (15:02:34 CET)
ARTICLE
|
doi:10.20944/preprints202312.1611.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
coronavirus disease 2019 (COVID-19); delta variant; tertiary care; mortality; vaccination; severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2)
Online: 21 December 2023 (08:07:07 CET)
REVIEW
|
doi:10.20944/preprints202312.1173.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
Alzheimer’s disease; transgenic animal model; amyloidogenesis; amyloid-beta; peptide; isoaspartate; zinc; α4β2 nicotinic acetylcholine receptor; aggregation seeding; anti-amyloid drug
Online: 15 December 2023 (12:23:06 CET)
ARTICLE
|
doi:10.20944/preprints202311.2007.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
myalgic encephalomyelitis, chronic fatigue syndrome, immunology, immunodeficiencies, mucosal barrier function, patient stratification, post-viral fatigue, intestinal barrier leakage, debilitating disease
Online: 30 November 2023 (16:56:26 CET)
ARTICLE
|
doi:10.20944/preprints202311.0453.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
Information and Communication Technology (ICT); Nephrology in Iberian Peninsula; Chronic Kidney Disease (CKD); Renal Replacement Therapy (RRT); Healthcare Professional (HCP)
Online: 7 November 2023 (11:53:15 CET)
ARTICLE
|
doi:10.20944/preprints202311.0214.v1
Subject:
Public Health And Healthcare,
Other
Keywords:
Alzheimer’s disease; α-lipoic acid; citicoline; extract of leaves green tea; extract of leaves olive tree; vitamin D3; selenium; scopolamine
Online: 3 November 2023 (05:04:23 CET)
HYPOTHESIS
|
doi:10.20944/preprints202310.2100.v2
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Alzheimer’ s disease; Angiotensin II; Angiotensin-converting enzyme 2; COVID-19; Brain; Dementia; Furin; Neurological disorders; SARS-CoV-2; Spike protein
Online: 12 February 2024 (15:48:57 CET)
ARTICLE
|
doi:10.20944/preprints202310.1435.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Alzheimer's Disease (AD); Convolutional Neural Networks (CNNs); Biomarkers of AD; Early clinical symptoms; Risk factors; Diagnosis of AD; Medical Images
Online: 23 October 2023 (10:29:48 CEST)
BRIEF REPORT
|
doi:10.20944/preprints202310.1087.v1
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
autoinflammatory diseases; SARS-CoV-2; vaccination; familial Mediterranean fever Adult-onset Still's disease; cryopyrin-associated periodic syndrome; systemic autoinflammatory diseases
Online: 17 October 2023 (11:54:44 CEST)
REVIEW
|
doi:10.20944/preprints202309.1538.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
cardiovascular disease; omega-3 polyunsaturated fatty acids; polar lipids; cardiovascular risk; thrombosis; platelet-activating factor (PAF); eicosanoids; resolvins; fish oil
Online: 22 September 2023 (08:44:08 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1456.v1
Subject:
Public Health And Healthcare,
Physical Therapy, Sports Therapy And Rehabilitation
Keywords:
circuit training; resistin; weighted vest; normal weight obesity; cardiopulmonary fitness; Vo2max; IL-6; hs-CRP, cardiovascular; cardiovascular disease risk factors
Online: 22 August 2023 (02:58:37 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0810.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
age-related macular degeneration; pachychoroid spectrum disease; polypoidal choroidal vasculopathy; pachychoroid neovasculopathy; ultra-wide-field swept-source optical coherent tomography
Online: 10 August 2023 (05:34:57 CEST)
REVIEW
|
doi:10.20944/preprints202308.0733.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
chronic kidney disease; uremic toxins; renal tubular transport; extracellular matrix remodeling; apoptosis resistance; inflammatory response; senescence-associated secretory phenotype factors
Online: 9 August 2023 (10:49:19 CEST)
REVIEW
|
doi:10.20944/preprints202306.1487.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
cell-free nucleic acids; cell-free DNA; circular DNA; microvescicles; inflammatory bowel disease; cGAS-STING; TLR9; oligonucleotides; bioinformatics; molecular therapies.
Online: 21 June 2023 (08:55:03 CEST)
ARTICLE
|
doi:10.20944/preprints202303.0389.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
antisense oligonucleotides; exon skipping; machine learning; ensemble learning; personalized medicine; n-of-1 therapy, splice switching; genetic disease; splicing; RNA
Online: 22 March 2023 (03:24:48 CET)
ARTICLE
|
doi:10.20944/preprints202303.0167.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
antisense oligonucleotides; exon skipping; machine learning; ensemble learning; personalized medicine; n-of-1 therapy; splice switching; genetic disease; splicing; RNA
Online: 9 March 2023 (04:43:55 CET)
ARTICLE
|
doi:10.20944/preprints202211.0200.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
neutropenia; neutropenic fever; chemotherapy; kidney function impairment; mild kidney disease; eGFR; CKD-EPI; G-CSF; Kaplan-Meier curves; survival analysis
Online: 10 November 2022 (11:11:40 CET)
CASE REPORT
|
doi:10.20944/preprints202210.0114.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
CADASIL; small vessel disease; retinal and choroidal blood flow disturbance; reduced amplitude of the P50 wave in PERG; retinal drusen
Online: 10 October 2022 (07:01:45 CEST)
REVIEW
|
doi:10.20944/preprints202209.0165.v1
Subject:
Medicine And Pharmacology,
Endocrinology And Metabolism
Keywords:
Diabetic foot; Diabetic neuropathies; Peripheral arterial disease; Foot ulcer; Gait; Walking; Postural balance; Wearable electronic devices; Gait analysis; Digital technology
Online: 13 September 2022 (09:28:22 CEST)
ARTICLE
|
doi:10.20944/preprints202208.0338.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
migratory birds; Newcastle disease virus-GVII; poultry; phylogenetics; sequence-independent; sin-gle-primer amplification (SISPA); velogenic; whole genome sequencing (WGS)
Online: 18 August 2022 (10:40:10 CEST)
ARTICLE
|
doi:10.20944/preprints202208.0181.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
COVID-19; SARS-CoV-2; disease severity; blood leukocyte transcriptome; WGCNA; transcriptional modules; differentially expressed genes; COVID-19 transcriptional markers
Online: 9 August 2022 (14:59:44 CEST)
REVIEW
|
doi:10.20944/preprints202205.0014.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
COVID-19; SARS-CoV-2; Diabetes; Neurological dysfunction; Cardiovascular complications; Pulmonary dysfunction; Renal dysfunction; bone loss; Eye disease; Gastrointestinal complications
Online: 23 May 2022 (11:00:06 CEST)
ARTICLE
|
doi:10.20944/preprints202202.0065.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Advanced Parkinson’s disease; Deep Brain Stimulation of the Subthalamic Nucleus; L-dopa/Carbidopa Intestinal Gel Infusion; Continuous Subcutaneous Apomorphine Infusion
Online: 4 February 2022 (07:18:08 CET)
ARTICLE
|
doi:10.20944/preprints202201.0174.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
alpha-synuclein; post-translational modifications; Parkinson’s disease; Multiple system atrophy; Lewy bodies; Lewy neurites; Glial cytoplasmic inclusions; phosphorylation; nitration; immunohistochemistry
Online: 12 January 2022 (14:31:13 CET)
REVIEW
|
doi:10.20944/preprints202109.0416.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Malassezia; Chronic diseases; psoriasis; atopic dermatitis; chronic rhinosinusitis; asthma; cystic fibrosis; HIV infection; inflammatory bowel disease; colorectal cancer; neurodegenerative diseases
Online: 24 September 2021 (08:13:07 CEST)
REVIEW
|
doi:10.20944/preprints202104.0240.v1
Subject:
Engineering,
Automotive Engineering
Keywords:
preeclampsia; cardiovascular disease; heart failure; ischemic/reperfusion injury; in vivo model system; in vitro model system; ex vivo model system
Online: 8 April 2021 (12:23:43 CEST)
REVIEW
|
doi:10.20944/preprints202103.0245.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
early life adversity; stress; psychosocial stress; hypothalamus-pituitary-adrenal axis; ageing; immuno-senescence; inflammageing; Developmental origins of health and disease
Online: 9 March 2021 (09:26:00 CET)
HYPOTHESIS
|
doi:10.20944/preprints202002.0147.v4
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Coronavirus; SARS-CoV-2; COVID-19; interferon; IFN; superinfection therapy; SIT; infectious bursal disease virus; IBDV; R903/78; safety; treatment
Online: 1 February 2021 (16:07:55 CET)
REVIEW
|
doi:10.20944/preprints202101.0426.v1
Subject:
Computer Science And Mathematics,
Algebra And Number Theory
Keywords:
deep learning; machine learning; ischemic stroke; demyelinating disease; image processing; computer aided diagnostics; brain MRI; CNN; White Matter Hyperintensities; VOSViewer
Online: 21 January 2021 (14:55:05 CET)
CONCEPT PAPER
|
doi:10.20944/preprints202009.0723.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Glycogen Storage Disease Type 1a, Glucose-6-phosphatase Catalytic Subunit (G6PC), Glucose-6-phosphatase (G6Pase), prime editing, mRNA delivery, CRISPR
Online: 30 September 2020 (08:05:17 CEST)
ARTICLE
|
doi:10.20944/preprints201911.0399.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
olivo-ponto-cerebellar atrophy (OPCA); Purkinje cells; Calcium/calmodulin dependent protein kinase II (CAMK2); Plastin (Fimbrin); Hirano bodies; Huntington’s disease
Online: 30 November 2019 (14:47:30 CET)
REVIEW
|
doi:10.20944/preprints201904.0037.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
second-hand smoke; cardiovascular disease; third-hand smoke; passive vaping; electronic cigarettes; heated tobacco; water pipe; myocardial infarction; stroke; diabetes
Online: 3 April 2019 (10:07:13 CEST)
REVIEW
|
doi:10.20944/preprints201812.0267.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Alzheimer’s disease; CTH gene; DNA methylation; epigenetics; epigenome-wide association study; methylome; MTHFR gene; nutrition; S-adenosylmethionine; vitamin B complex
Online: 24 December 2018 (04:48:53 CET)
ARTICLE
|
doi:10.20944/preprints201811.0463.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Mass Spectroscopy, Bioinformatics, FGF14, Voltage Gated Channels, Schizophrenia, Alzheimer’s Disease, Sex-Specific Differences, Synaptic Plasticity, Cognitive Impairment, Excitatory/Inhibitory Tone
Online: 19 November 2018 (11:54:50 CET)
REVIEW
|
doi:10.20944/preprints201806.0137.v1
Subject:
Medicine And Pharmacology,
Other
Keywords:
opportunity; challenge; perspective; health data; disease prediction; clinical outcome prediction; healthcare process; data quality; quantity and quality analysis; artificial intelligence
Online: 8 June 2018 (13:22:08 CEST)
ARTICLE
|
doi:10.20944/preprints202407.1672.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
immune imbalance; Immune Imbalance Transcriptomics; IIT; B-cell lymphoma; Systemic Lupus Erythematosus (SLE); RNA-seq; algorithm; drug discovery; cancer; autoimmune disease
Online: 22 July 2024 (09:33:39 CEST)
REVIEW
|
doi:10.20944/preprints202407.1479.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Inborn errors of immunity (IEI); Chronic granulomatous disease (CGD); NADPH oxidase; Nitroblue tetrazolium (NBT); Dihydrorhodamine (DHR); Genetic testing; Genomic testing; Screening
Online: 18 July 2024 (14:38:08 CEST)
ARTICLE
|
doi:10.20944/preprints202406.1966.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Akt; cell death; GAPDH; ischemia-like insult; neuroprotection; Nrf2; phosphorylation; Rasagiline; ROS; PC 12 neuronal model; α-synuclein; Parkinson’s disease; stroke
Online: 1 July 2024 (08:40:53 CEST)
ARTICLE
|
doi:10.20944/preprints202404.0469.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
Alzheimer’ s disease; amyloid β peptide; human serum albumin; low-molecular-weight ligand; protein-ligand interaction; surface plasmon resonance spectroscopy
Online: 7 April 2024 (10:18:10 CEST)
COMMUNICATION
|
doi:10.20944/preprints202403.0753.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
ambulatory electrocardiographic markers; coronavirus disease-19; COVID-19; global cardiac ischemia; Holter electrocardiograph; myocardial remodeling; SARS-CoV-2; sudden cardiac death
Online: 13 March 2024 (07:31:31 CET)
REVIEW
|
doi:10.20944/preprints202403.0461.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
Western-type diet; Mediterranean-type diet; gut microbiota; short-chain fatty acid; trimethylamine N-oxide; bile acids; cardiovascular disease; atherosclerosis; nutrients
Online: 7 March 2024 (14:56:59 CET)
REVIEW
|
doi:10.20944/preprints202402.1614.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
autoimmune diseases; type 2 hypersensitivity; Tr1; SLE; Myasthenia gravis; Grave’ s disease; GvHD; Sjogren’ s syndrome; AIHA; ITP; dermatomyositis
Online: 28 February 2024 (13:48:04 CET)
REVIEW
|
doi:10.20944/preprints202402.1401.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Biomarker; HCC (Hepatocellular Carcinoma); LC-SPIK (Liver Cancer specific Serine Protease Inhibitor Kazal); AFP (Alpha-Fetoprotein); NAFLD (nonalcoholic fatty liver disease)
Online: 26 February 2024 (12:01:59 CET)
REVIEW
|
doi:10.20944/preprints202402.1245.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Parkinson’ s disease; type 2 diabetes mellitus; GLP1-R agonists; GLP-1; exendin-4; liraglutide; lixisenatide; semaglutide; clinical trials; neurodegeneration
Online: 22 February 2024 (12:38:30 CET)
REVIEW
|
doi:10.20944/preprints202312.2337.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
COVID-19; SARS-CoV-2; transcriptomics; RNA-seq; scRNA-seq; inflammation; pneumonia; neuronal COVID; acute respiratory disease syndrome; multisystem inflammatory syndrome
Online: 30 December 2023 (16:01:23 CET)
ARTICLE
|
doi:10.20944/preprints202312.0764.v1
Subject:
Biology And Life Sciences,
Ecology, Evolution, Behavior And Systematics
Keywords:
Sapronotic disease; Mycobacterium ulcerans; river catchment area; pathogen transmission; saprophytic stage; metapopulation and metacommunity dynamics
Online: 12 December 2023 (04:43:46 CET)
ARTICLE
|
doi:10.20944/preprints202309.2168.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
brain ischemia; Alzheimer’s disease; CA3 area; amyloid protein precursor; amyloid; α-secretase; β-secretase; presenilin 1 and 2; tau protein; genes
Online: 30 September 2023 (08:01:45 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0255.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
oral squamous cell carcinoma; prognosis; overall survival; disease free survival; connexin 43; EMMPRIN; E-cadherin; vimentin; metastasis; epithelial-to-mesenchymal transition
Online: 5 September 2023 (07:54:11 CEST)