ARTICLE
|
doi:10.20944/preprints202309.1323.v1
Subject:
Chemistry And Materials Science,
Inorganic And Nuclear Chemistry
Keywords:
dual emission; ruthenium; polypyridyl ligand; electrochemistry; photophysics
Online: 19 September 2023 (13:28:20 CEST)
ARTICLE
|
doi:10.20944/preprints202401.0084.v1
Subject:
Chemistry And Materials Science,
Inorganic And Nuclear Chemistry
Keywords:
lanthanide oxygen cluster; magnetocaloric effect; magnetic refrigerant materials; rhodamine ligand
Online: 3 January 2024 (02:15:52 CET)
ARTICLE
|
doi:10.20944/preprints201805.0380.v1
Subject:
Chemistry And Materials Science,
Theoretical Chemistry
Keywords:
molecular dynamics simulation; biophenols; natural compounds; amyloid fibrils; Alzheimer’s disease; ligand-protofiber interactions
Online: 27 May 2018 (13:09:22 CEST)
ARTICLE
|
doi:10.20944/preprints202408.1826.v1
Subject:
Chemistry And Materials Science,
Polymers And Plastics
Keywords:
titanium; catalyst; homogeneous catalyst; copolymerization; half-titanocene; ethylene; styrene; ligand effect; cyclopentadienyl
Online: 26 August 2024 (11:30:09 CEST)
REVIEW
|
doi:10.20944/preprints201811.0409.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
G quadruplex, Oncogene, ligand, cancer
Online: 16 November 2018 (11:34:24 CET)
ARTICLE
|
doi:10.20944/preprints202311.1953.v1
Subject:
Chemistry And Materials Science,
Organic Chemistry
Keywords:
palladium-catalyzed; 2-pyridone ligand; tertiary aldehydes
Online: 30 November 2023 (05:45:42 CET)
ARTICLE
|
doi:10.20944/preprints201902.0124.v4
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
enzymes Cyclooxygenase, ligand, metabolites, antiinflammatory, Molecular Docking
Online: 29 May 2019 (11:39:02 CEST)
ARTICLE
|
doi:10.20944/preprints202405.0060.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
Enthalpy-Entropy compensation; Protein Ligand Interactions; Thermodynamic Parameters
Online: 1 May 2024 (07:45:22 CEST)
REVIEW
|
doi:10.20944/preprints202404.0801.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
malaria; ligand-receptor interaction; phage display; vaccine target
Online: 11 April 2024 (11:29:14 CEST)
BRIEF REPORT
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
SARS-CoV2; spike; receptor–ligand docking; super infection
Online: 20 March 2020 (08:30:40 CET)
ARTICLE
|
doi:10.20944/preprints202404.0469.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
Alzheimer’ s disease; amyloid β peptide; human serum albumin; low-molecular-weight ligand; protein-ligand interaction; surface plasmon resonance spectroscopy
Online: 7 April 2024 (10:18:10 CEST)
ARTICLE
|
doi:10.20944/preprints202401.1836.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Malaria; Virtual Screening; Molecular Dynamics Simulation; Pharmacophore; Modelling; Ligand
Online: 25 January 2024 (14:26:11 CET)
ARTICLE
|
doi:10.20944/preprints202104.0245.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
bis(tetrazine); coordination; host-guest; ligand; silver; XRD structure
Online: 8 April 2021 (14:27:58 CEST)
ARTICLE
|
doi:10.20944/preprints201902.0064.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Dopamine receptors, Molecular Docking, Molecular Dynamics, Receptor-Ligand Interactions
Online: 6 February 2019 (13:54:13 CET)
REVIEW
|
doi:10.20944/preprints201810.0312.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
upconversion; nanoparticles; lanthanide; surface modification; functionalisation; ligand engineering; silanisation;
Online: 15 October 2018 (12:59:30 CEST)
REVIEW
|
doi:10.20944/preprints202407.1270.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
Enterovirus; Multi-target directed ligand; Clinical Trials; Combination; Drug design
Online: 16 July 2024 (08:27:11 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1903.v1
Subject:
Chemistry And Materials Science,
Theoretical Chemistry
Keywords:
Analysis of magnetic shieldings; electronic mechanisms; LRESC-Loc; Ligand-dependent
Online: 26 May 2023 (09:41:54 CEST)
REVIEW
|
doi:10.20944/preprints202302.0510.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Metal-Based Drugs; CuZn; Anti-Chemoresistance; Osteosarcoma Therapy; Ligand Biosensors.
Online: 28 February 2023 (06:51:00 CET)
ARTICLE
|
doi:10.20944/preprints202404.1891.v1
Subject:
Chemistry And Materials Science,
Inorganic And Nuclear Chemistry
Keywords:
single-molecular nanomedicine; porphyrin ligand; chemodynamic therapy; ferroptosis; breast cancer therapy
Online: 29 April 2024 (09:55:51 CEST)
BRIEF REPORT
|
doi:10.20944/preprints202004.0476.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
androgen insensitivity syndrome; androgen receptor; ligand binding domain; pathogenic mutation; bioinformatics
Online: 27 April 2020 (03:59:38 CEST)
ARTICLE
|
doi:10.20944/preprints201911.0071.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
NMDAR; amantadine; dansyl; fluorescent ligand; energy minima; molecular modelling; fluorescent bioassay
Online: 7 November 2019 (04:17:07 CET)
ARTICLE
|
doi:10.20944/preprints201910.0281.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
protein structural dynamics; NQO1; ligand binding; protein stability; allostery; protein degradation
Online: 24 October 2019 (15:41:46 CEST)
REVIEW
|
doi:10.20944/preprints202406.1388.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
acute myeloid leukemia; NPM1 mutation; immunogenic subtype; Programmed Death Ligand 1; immunotherapy
Online: 20 June 2024 (08:30:47 CEST)
ARTICLE
|
doi:10.20944/preprints202401.1778.v1
Subject:
Chemistry And Materials Science,
Organic Chemistry
Keywords:
Rhodium; tridentate ligand; tandem reaction; allylic decarboxylation; cycloaddition; C−N Bond Formation
Online: 25 January 2024 (05:18:35 CET)
ARTICLE
|
doi:10.20944/preprints202309.1826.v1
Subject:
Chemistry And Materials Science,
Inorganic And Nuclear Chemistry
Keywords:
coordination polymers; coordination networks; triazole ligand; iron(II); self-assembly; hydrogen bonds
Online: 27 September 2023 (07:17:13 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1131.v1
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
adipokine; chemokine (C-C motif) ligand 2; interleukin-6; leptin; neonatal; preeclampsia
Online: 16 May 2023 (09:00:30 CEST)
ARTICLE
|
doi:10.20944/preprints202303.0082.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
CENPA; cell cycle; pan-cancer; diagnostic; prognostic; glioma; immune; protein-ligand docking
Online: 6 March 2023 (02:38:13 CET)
REVIEW
|
doi:10.20944/preprints202211.0484.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
G-quadruplex DNA; G4-ligand; class switch recombination; transcriptional regulation; B lymphocytes
Online: 28 November 2022 (01:20:40 CET)
ARTICLE
|
doi:10.20944/preprints202204.0053.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Programmed death ligand-1; Natural products; Immunotherapy; Neoenactin B1; Molecular dynamics simulation
Online: 7 April 2022 (04:08:19 CEST)
ARTICLE
|
doi:10.20944/preprints202011.0618.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Neprilisin; Docking; Molecular Dynamics Simulation; MM-PBSA; Ligand Efficiency Metrics; ADME-Tox
Online: 24 November 2020 (14:21:22 CET)
REVIEW
|
doi:10.20944/preprints202003.0285.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
HIF-1α; NQO1; hypoxia; angiogenesis; cancer; protein:protein interactions; ligand binding; proteasomal degradation
Online: 18 March 2020 (08:45:33 CET)
REVIEW
|
doi:10.20944/preprints201608.0054.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
influenza virus; antiviral agent; proteomics; phosphoproteomics; metabolomics; transcriptomics; genomics; virtual ligand screening
Online: 5 August 2016 (12:41:07 CEST)
ARTICLE
|
doi:10.20944/preprints202407.2074.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
TNF-related apoptosis-inducing ligand; Eugenol; death receptor; endoplasmic reticulum stress; ROS; siRNA
Online: 26 July 2024 (04:27:29 CEST)
ARTICLE
|
doi:10.20944/preprints202406.1413.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
Acute lymphoblastic leukemia; RANK Ligand; Osteoprotegerin; 25(OH)D; Corticosteroids; Bone turnover markers
Online: 20 June 2024 (09:40:20 CEST)
ARTICLE
|
doi:10.20944/preprints202304.1114.v1
Subject:
Chemistry And Materials Science,
Inorganic And Nuclear Chemistry
Keywords:
C,N-chelate ligand; o-carborane; organoaluminum complexes; X-ray crystallography; intramolecular stabilization
Online: 28 April 2023 (04:50:36 CEST)
ARTICLE
|
doi:10.20944/preprints202303.0502.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Tuberculosis; Biscoumarins; Ligand molecules; DprE1; Anti-tuberculosis activity; Molecular docking; MD Simulation; Cytotoxicity
Online: 29 March 2023 (04:21:45 CEST)
ARTICLE
|
doi:10.20944/preprints202011.0292.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Alzheimer's disease; BACE1; Molecular dynamics; MM/GBSA; Inhibitors; Drug likeness; Ligand efficiency, Kd.
Online: 10 November 2020 (09:10:50 CET)
ARTICLE
|
doi:10.20944/preprints201901.0062.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
small molecule; ligand; receptor; docking; molecular dynamics; DNA repair; inhibition; PCNA; ADME; toxicology
Online: 8 January 2019 (11:10:26 CET)
ARTICLE
|
doi:10.20944/preprints202403.1834.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
Lung cancer; Epigenetic profiling; Methylome; Methylation analysis; Programmed cell death ligand 1; Precision medicine
Online: 29 March 2024 (10:53:14 CET)
ARTICLE
|
doi:10.20944/preprints202403.1433.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
FLT3 Inhibitors; Ligand-based Drug Design; Computer-Aided Drug Design; QSAR Modeling; AML Treatment
Online: 25 March 2024 (08:47:40 CET)
ARTICLE
|
doi:10.20944/preprints202311.1841.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
2D semiconductors; chirality; CdSe nanoplatelets; circular dichroism; amino acids, excitons; ligand exchange, colloidal synthesis
Online: 29 November 2023 (06:11:04 CET)
COMMUNICATION
|
doi:10.20944/preprints202311.1583.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Protein-ligand interaction; Curcumin; Jacalin; Lectin; Fluorescence; Cytotoxicity; Breast cancer cells; MDA-MB-231
Online: 26 November 2023 (06:30:33 CET)
ARTICLE
|
doi:10.20944/preprints202307.0262.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
DCL ligand; iodine radioisotopes; radiolabeled pharmaceuticals; targeted delivery; prostatic specific membrane antigen; prostate cancer
Online: 5 July 2023 (04:43:46 CEST)
ARTICLE
|
doi:10.20944/preprints201712.0162.v1
Subject:
Chemistry And Materials Science,
Inorganic And Nuclear Chemistry
Keywords:
coordination polymer with interdigitated structure; MOF; gate-opening; thiazolo[5,4-d]thiazole, mixed-ligand
Online: 22 December 2017 (04:31:57 CET)
ARTICLE
|
doi:10.20944/preprints201709.0157.v1
Subject:
Chemistry And Materials Science,
Organic Chemistry
Keywords:
rare earth metal complexes; 1,3-bis(oxazolinymethylidene)isoindoline ligand; polymerization; isoprene; cis-1,4-selectivity
Online: 29 September 2017 (14:50:39 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0048.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
tetrahydropyrazolopyridine; 5-nitrofuran derivatives; ESKAPE pathogens; antibacterial testing; nitroreductase; flexible docking; strained ligand-protein interactions
Online: 2 August 2023 (04:31:53 CEST)
ARTICLE
|
doi:10.20944/preprints202001.0219.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
protruding features; spherical virus; point arrays; surface modifications; VLP; drug delivery; icosahedral; nanomedicine; ligand binding
Online: 20 January 2020 (06:59:09 CET)
ARTICLE
|
doi:10.20944/preprints202309.0347.v1
Subject:
Medicine And Pharmacology,
Tropical Medicine
Keywords:
Fasciola hepatica; triclabendazole; anthelmintic-resistance; amino acid-substitution; binding-pocket; ligand-protein docking; protein 3D modeling.
Online: 6 September 2023 (10:24:35 CEST)
REVIEW
|
doi:10.20944/preprints202203.0032.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
artificial intelligence; machine learning; drug design; covid-19; structure-based drug design; ligand-based drug design
Online: 2 March 2022 (03:00:37 CET)
ARTICLE
|
doi:10.20944/preprints201907.0215.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Platinum, N-heterocyclic carbene ligand, anticancer activity, DNA interaction, optical tweezers technique, liquid phase AFM microscop
Online: 18 July 2019 (10:17:27 CEST)
ARTICLE
|
doi:10.20944/preprints202312.1205.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
idiopathic pulmonary fibrosis; fibrogenesis; chemokine receptor; ligand-induced internalization; co-immunoprecipitation; collagen; alpha-smooth muscle actin; FGF2
Online: 15 December 2023 (16:01:32 CET)
REVIEW
|
doi:10.20944/preprints202209.0201.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
ligand-based pharmacophores; structure-based pharmacophores; virtual screening; drug design; machine learning; molecular dynamics; de novo design
Online: 14 September 2022 (09:10:58 CEST)
REVIEW
|
doi:10.20944/preprints202106.0023.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
cancer; cardiovascular disease; chemokine (C-C motif) ligand 2; fatty liver; infection; inflammation; metabolism; obesity; paraoxonase-1
Online: 1 June 2021 (10:46:20 CEST)
ARTICLE
|
doi:10.20944/preprints202102.0046.v1
Subject:
Chemistry And Materials Science,
Organic Chemistry
Keywords:
bifunctional catalyst; metal-ligand cooperation; dinuclear complex; iridacycle; cyclometalation; asymmetric transfer hydrogenation; cyanation; 1,1-binaphthyl; axial chirality
Online: 1 February 2021 (14:35:48 CET)
REVIEW
|
doi:10.20944/preprints202006.0147.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
PSP; Progressive Supranuclear Palsy; 4R-tau; four-repeat tau; MAPT; Microtubule-associated ligand; PET; Positron Emission Tomography
Online: 12 June 2020 (09:41:06 CEST)
ARTICLE
|
doi:10.20944/preprints202004.0068.v2
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
coronavirus; COVID-19; hACE-2; MPro; multi-target-directed ligand; protease inhibito; RdRp; SARS-CoV-2 virus
Online: 9 April 2020 (05:13:05 CEST)
ARTICLE
|
doi:10.20944/preprints201705.0216.v1
Subject:
Chemistry And Materials Science,
Applied Chemistry
Keywords:
MOF; catalyst; recyclable Cu-MOF-74; ligand-free; O-arylation reaction; 4-nitrobenzaldehyde; phenol; 4-formyldiphenyl ether
Online: 30 May 2017 (09:31:36 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1806.v1
Subject:
Chemistry And Materials Science,
Inorganic And Nuclear Chemistry
Keywords:
europium(III) complexes; scorpionate; tripodal ligand; trispyrazolylmethane; tris(3,5-dimethyl-1-pyrazolyl)methane; magnetic properties; spin-orbit coupling
Online: 25 August 2023 (13:34:10 CEST)
ARTICLE
|
doi:10.20944/preprints202307.2130.v1
Subject:
Chemistry And Materials Science,
Applied Chemistry
Keywords:
cyclic voltammetry; electron paramagnetic resonance; DFT calculations; UV-VIS/NIR; phenoxyl radical; pincer complex; platinum complex; NHC ligand
Online: 1 August 2023 (03:38:51 CEST)
ARTICLE
|
doi:10.20944/preprints201912.0374.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
alpha-fetoprotein; estrogens; selective estrogen receptor modulators; homology-based modeling; molecular docking; protein-ligand interaction; amino acid substitutions
Online: 29 December 2019 (08:08:23 CET)
ARTICLE
|
doi:10.20944/preprints201908.0182.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
indirubin-3′-monoxime; p53; death receptor 5; TNF-related apoptosis-inducing ligand; transcription factor C/EBP homologous protein
Online: 17 August 2019 (04:19:38 CEST)
ARTICLE
|
doi:10.20944/preprints202305.0636.v1
Subject:
Chemistry And Materials Science,
Materials Science And Technology
Keywords:
phosphorescent organic light-emitting diodes; heteroleptic Pt(II) complexes; C^N chelate; ancillary ligand; time-dependent density functional theory
Online: 9 May 2023 (10:25:25 CEST)
ARTICLE
|
doi:10.20944/preprints202312.0794.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
co-delivery; silica nanoparticles; vaccine adjuvant; toll-like receptor 7/8 (TLR7/8) ligand; INI-4001; influenza virus; hemagglutinin H7
Online: 12 December 2023 (05:25:44 CET)
REVIEW
|
doi:10.20944/preprints202308.0821.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
ligand-free receptor signaling; inverse agonist; neutral antagonist; μ opioid receptor; opioid dependence; 6β-naltrexol; psychedelics; LSD; 5-HT2A; GHSR
Online: 10 August 2023 (09:48:03 CEST)
ARTICLE
|
doi:10.20944/preprints201812.0173.v2
Subject:
Chemistry And Materials Science,
Organic Chemistry
Keywords:
2-(Adamantan-1-yl)-2H-isoindole-1-carbonitrile; X-ray diffraction; DFT; molecular orbital calculations; fluorescence; docking; nNOS; fluorescent ligand
Online: 14 December 2018 (11:41:20 CET)
ARTICLE
|
doi:10.20944/preprints202405.1338.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
tumor necrosis factor-related apoptosis-inducing ligand; gintonin-enriched fraction; human renal cell carcinoma; apoptosis; mu-2-related death-inducing gene
Online: 21 May 2024 (04:53:52 CEST)
REVIEW
|
doi:10.20944/preprints201707.0019.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
affective disorders; alzheimer’s disease; l-Deprenyl (Selegiline); donepezil; galantamine; value; inhibitor constant; mechanism-based inhibition; multitarget-directed ligand (MTDL); rasagiline; rivastigmine
Online: 11 July 2017 (05:58:53 CEST)
ARTICLE
|
doi:10.20944/preprints202310.1074.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
mixed-based combinatorial library; structure–activity relationships; cyclic peptide; mu-opioid receptor; delta-opioid receptor; bifunctional ligand; antinociception; opioid antagonist; opioid liabilities
Online: 17 October 2023 (11:21:32 CEST)
ARTICLE
|
doi:10.20944/preprints202407.0549.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
single-molecule FRET; single-molecule microscopy; receptor-ligand interaction; T cell receptor; bond lifetime quantification; T cell activation; antigen sensitivity; simulation; survival analysis
Online: 9 July 2024 (03:56:29 CEST)
ARTICLE
|
doi:10.20944/preprints202310.1322.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Drynaria fortunei-derived polysaccharides; bone marrow-derived macrophages; osteoclastogenesis; receptor activator of nuclear factor-κB ligand; nuclear factor of activated T cells 1
Online: 20 October 2023 (12:08:32 CEST)
REVIEW
|
doi:10.20944/preprints202306.1853.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
interleukin-1 beta (IL-1β); immune-checkpoint inhibitors (ICIs); non-small cell lung cancer (NSCLC); programmed death ligand 1 (PD-L1); therapeutic resistance
Online: 27 June 2023 (07:16:09 CEST)
ARTICLE
|
doi:10.20944/preprints202001.0122.v1
Subject:
Physical Sciences,
Biophysics
Keywords:
cervical adenocarcinoma; immune-checkpoint inhibitor; programmed cell death-1(PD-1); programmed cell death-ligand 1(PD-L1); CD8 expression; lymphocyte; survival analysis
Online: 12 January 2020 (15:01:23 CET)
ARTICLE
|
doi:10.20944/preprints202309.0469.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
biomarker; C-X-C motif chemokine ligand 10; growth differentiation factor 15; idiopathic inflammatory myopathy; immune-mediated necrotizing myopathy; myositis; sporadic inclusion body myositis
Online: 7 September 2023 (13:35:58 CEST)
REVIEW
|
doi:10.20944/preprints202308.0434.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
In silico studies; drug discovery; SARS-CoV-2; molecular docking; virtual screening; molecular dynamics simulations; drug candidates; antiviral activity; receptor-ligand complex; drug design
Online: 4 August 2023 (11:11:21 CEST)
ARTICLE
|
doi:10.20944/preprints202304.1090.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Invasive lobular cancer; pleomorphic invasive lobular cancer; tumor-infiltrating lymphocytes; programmed cell death 1; programmed cell death ligand 1; 22C3 assay; SP142 assay; survival
Online: 28 April 2023 (03:22:03 CEST)
ARTICLE
|
doi:10.20944/preprints202403.0398.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
immune escape; tumor immunity; immune checkpoint; oral squamous cell carcinoma; programmed death receptor-1 (PD-1); programmed cell death 1-ligand 1 (PD-L1); CD47
Online: 7 March 2024 (07:49:57 CET)
ARTICLE
|
doi:10.20944/preprints201804.0278.v1
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
monocyte chemoattractant protein-1; MCP-1; C-C motif chemokine ligand 2; CCL2; childhood asthma; bronchial asthma; severe asthma; cystic fibrosis; chronic obstructive pulmonary disease
Online: 23 April 2018 (09:00:00 CEST)
ARTICLE
|
doi:10.20944/preprints201612.0068.v2
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
modulation of nuclear gene expression; mitochondrial 18 kDa translocator protein (TSPO); TSPO ligand; PK 11195; 2-Cl-MGV-1; retrograde mitochondrial-nuclear signaling pathway; microscopy; mitochondria; cell nucleus
Online: 17 March 2017 (17:28:28 CET)
REVIEW
|
doi:10.20944/preprints202405.0601.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Data science; Big data; Data mining; Bioinformatics; Chemometric; Medicinal chemistry; Targets; Knowledge discovery; Artificial intelligence, Machine learning, Deep learning; Data integration; Metadata, Database; QSAR; Collaborative drug discovery; Structure-based drug design; Ligand-based drug discovery; Clinical trials; Product development.
Online: 10 May 2024 (10:15:20 CEST)
ARTICLE
|
doi:10.20944/preprints202403.0518.v1
Subject:
Computer Science And Mathematics,
Discrete Mathematics And Combinatorics
Keywords:
COVID19; Chern-Simons Topological; QED (Quantum Electrodynamics); Homeopathic medicine; Water Memory; AI-Quantum computing; Quantum-Inspired Evolutionary Algorithm Predictive Toxicology; QSAR Quantum gates; CS Supergravity Quantum Foam; Cheminformatics artificial intelligence; Phase Data Mining; Machine Learning; Euclid Chemical space exploration; (bosonic) Quantum fields Theory (QFT); Angiotensin Receptor Neprilysin targeted DRVYIHPFX mimetic Holomorphic Ligands; Hidden Entanglement Negativity Translations; Uncertainty Quantum Relationships; Quantum fields theory; Quantum information; HyperGeometric Functions; Chemical Block Systems; Black Hole Paradox Generalizations; SphericalHarmonicY-Supersymmetry breaking foundations; WhittakerM Functions; Hypergeometric1F1 Functions; Turing Machine Learning Ruled Calculations; Avogadro Number’ s oriented Quantum Homeopathy Hidden Entanglement Negativities; Quantum foam; non-commutative geometry; small molecule ligand engineering; prot
Online: 11 March 2024 (03:52:07 CET)