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Preprint ARTICLE | doi:10.20944/preprints202207.0080.v1

A Density Functional Theory and Information-Theoretic Approach Study of Interaction Energy and Polarizability for Base Pairs and Peptides

Dongbo Zhao, Shubin Liu, Dahua Chen

Subject: Chemistry And Materials Science, Theoretical Chemistry Keywords: density functional theory (DFT); information-theoretic approach (ITA); base pairs; peptides; molecular polarizability

Online: 6 July 2022 (03:04:51 CEST)

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Preprint REVIEW | doi:10.20944/preprints202201.0316.v1

“Superwobbling” and tRNA-34 wobble and tRNA-37 anticodon loop modifications in evolution and devolution of the genetic code

Lei Lei, Zachary Frome Burton

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: elongation factor Tu; evolution of the genetic code; four-way wobbling; genetic code degeneracy; inosine; mitochondria; queuosine; superwobbling; tRNA modification; tRNA wobble U modification

Online: 21 January 2022 (08:53:37 CET)

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Preprint ARTICLE | doi:10.20944/preprints202111.0452.v1

Southern African Large Frame Indigenous Veld Goat and Boer Goat Wether and Buck Tenderness and Colour of Six Muscles

Gertruida L. van Wyk, Louwrens C. Hoffman, Phillip E. Strydom, Lorinda Frylinck

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: Cape Lob Ear; Cape Speckled; meat goat breeds; meat tenderness; meat colour; collagen; chevon

Online: 24 November 2021 (10:47:43 CET)

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Preprint DATA DESCRIPTOR | doi:10.20944/preprints202104.0351.v1

Effectiveness and Implications of Lecture Based Instruction in Maternal and Childcare to Students Social Competency Skills and Community Awareness

Cherry Rose Malgapo, Nieves Adjarani

Subject: Public Health And Healthcare, Primary Health Care Keywords: lecture based instruction; actual community-based instruction; maternal and child care; social competency skills; community awareness

Online: 13 April 2021 (12:47:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202103.0153.v1

Analytical and Semi-Analytical Solutions for the Self and Mutual Inductances of Concentric Coplanar Ordinary and Bitter Disk Coils

Slobodan Babic

Subject: Physical Sciences, Applied Physics Keywords: Ordinary disk coils; Bitter disk coils; mutual inductance, self-inductance.

Online: 4 March 2021 (10:12:28 CET)

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Preprint ARTICLE | doi:10.20944/preprints202009.0695.v1

Clays, Limestone and Biochar Affect the Bioavailability and Geochemical Fractions of Cadmium and Zinc from Zn-Smelter Polluted Soils

Altaf Hussain Lahori, Monika Mierzwa-Hersztek, Erdona Demiraj, Rachida Idir, Thi Tuyet Xuan Bui, Dinh Duy Vu, Amanullah Channa, Naeem Akhtar Samoon, Zengqiang Zhang

Subject: Environmental And Earth Sciences, Soil Science Keywords: clay minerals; limestone; biochar; trace elements; bio-availability; alkaline degraded soils

Online: 28 September 2020 (17:52:02 CEST)

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Preprint REVIEW | doi:10.20944/preprints202009.0654.v1

BARD1 and Breast Cancer: The Possibility of Creating Screening Tests and New Preventive and Therapeutic Pathways for Predisposed Women

Marcin Śniadecki, Michał Brzeziński, Katarzyna Darecka, Dagmara Klasa-Mazurkiewicz, Patryk Poniewierza, Marta Krzeszowiec, Natalia Kmieć, Dariusz Wydra

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: breast cancer; BARD1; surveillance; management; genetic testing; predisposition; susceptibility; neoadjuvant; chemotherapy

Online: 26 September 2020 (17:32:52 CEST)

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Preprint REVIEW | doi:10.20944/preprints202008.0371.v1

BARD1 and Breast Cancer: the Possibility of Creating Screening Tests and New Preventive and Therapeutic Pathways for Predisposed Women

Marcin Śniadecki, Michał Brzeziński, Katarzyna Darecka, Dagmara Klasa-Mazurkiewicz, Patryk Poniewierza, Marta Krzeszowiec, Natalia Kmieć, Dariusz Wydra

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: breast cancer; BARD1; surveillance; management; genetic testing; predisposition; susceptibility; neoadjuvant; chemotherapy

Online: 18 August 2020 (03:08:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201810.0121.v1

Cell Cycle Arrest and Cytotoxic Effects of SAHA and RG7388 Mediated through p21^WAF1/CIP1 and p27^KIP1in Cancer Cells

Umamaheswari Natarajan, Thiagarajan Venkatesan, Vijayaraghavan Radhakrishnan, Shila Samuel, Appu Rathinavelu

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: SAHA; RG7388; MDM2; p53; p21; cell cycle arrest; cell death

Online: 7 October 2018 (11:33:18 CEST)

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Alterations in gene expressions are often due to epigenetic modifications that can lead to significant influence on cancer development, growth, and progression. The main epigenetic modifications observed in human are methylation and acetylation. In this regard, the HDAC inhibitors (HDACi) such as SAHA (Vorinostat), which can exert epigenetic alterations through impacting the acetylation status of histones, are in clinical trials as a new class of drugs with promising effects on the cancer growth and metastatic process. The small molecule RG7388 is a newly developed inhibitor that is specific for an oncogene-derived protein called MDM2, which is in clinical trials for the treatment of various types of cancers. One of the common characteristics for these two drugs is their ability to induce p21 expression through distinct mechanisms in MCF-7 and LNCaP cells. This difference was expected trigger cell cycle arrest and cell death through intra-cellular mechanisms that are not identical. Hence, the molecular mechanism whereby SAHA can induce cell cycle arrest and trigger necrosis, apoptosis or necroptosis is still evolving. Similarly, the ability of RG7388 for producing anticancer effect is undergoing thorough investigation, since it can produce p53 dependent and p53 independent effects. In this study we performed experiments to measure the cell cycle arrest effects of SAHA and RG7388 on using MCF-7 and LNCaP cells. The cytotoxicity, cell cycle arrest and apoptosis/necroptosis effects of the treatments were assessed by using Trypan Blue Dye Exclusion (TBDE) method, MTT assay, Fluorescence assay with DEVD-amc fluorogenic substrate and Immunoblotting methods. Our results from MCF-7 and LNCaP cells confirmed that SAHA and RG7388 treatments were able to induce cell death via combination of cell cycle arrest and cytotoxic mechanisms. We are speculating that our findings could lead to the development of newer treatments for breast and prostate cancers using this type of combinations.

Preprint ARTICLE | doi:10.20944/preprints201808.0515.v1

Seed Rain and Seedling Establishment of Picea glauca and Abies balsamea after Partial Cutting in Plantations and Natural Stands

Laurent Gagné, Luc Sirois, Luc Lavoie

Subject: Biology And Life Sciences, Forestry Keywords: balsam fir; white spruce; seedlings; partial cut; plantation; naturals stands; light; seed rain

Online: 30 August 2018 (05:36:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.1563.v1

Sustainable Development of Universities in Poland – Identification of the Status and Possibilities of Support

Anna Katarzyna Stasiuk-Piekarska, Monika Michalska, Małgorzata Hordyńska

Subject: Business, Economics And Management, Human Resources And Organizations Keywords: sustainable development; ESG; CSRD directive; good university practices

Online: 22 January 2024 (07:49:50 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0879.v1

Modelling of Fatigue Delamination Growth and Prediction of Residual Tensile Strength of Thermoplastic Coupons

Niki Tsivouraki, Konstantinos Tserpes, Ioannis Sioutis

Subject: Engineering, Aerospace Engineering Keywords: Thermoplastic composites; Delamination; Residual strength; Cohesive zone modeling; Progressive damage modeling; Finite element analysis

Online: 12 December 2023 (10:44:24 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0153.v1

Survey of Veterinarians’ Experiences and Perceptions of the Diagnosis of Spironucleosis in Game Birds

Matthew Hylands, Natasha Hands, Michael Clark, Hany Elsheikha

Subject: Biology And Life Sciences, Parasitology Keywords: spironucleosis; spironucleus; hexamitosis; protozoan parasites; game birds; diagnosis; questionnaires

Online: 4 December 2023 (07:42:59 CET)

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Preprint REVIEW | doi:10.20944/preprints202311.1388.v1

A Review of Distribution and Profiles of HBCD in Different Environmental Media of China

Jing Lin Deng, Wen bin Liu, Li rong Gao, Tian qi Jia, Yun chen He, Tian ao Mao, Javid Hussain

Subject: Environmental And Earth Sciences, Pollution Keywords: HBCD; occurrence and distribution; environmental media

Online: 22 November 2023 (06:30:08 CET)

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Preprint ARTICLE | doi:10.20944/preprints202309.1578.v1

Prevalence and Quantification of the Effects of Sexual Harassment Victimization of School-Aged Adolescents

Verónica Marcos, Dolores Seijo, Álvaro Montes, Ramón Arce

Subject: Social Sciences, Psychology Keywords: Internalizing Mental Health Problems; Externalizing Mental Health Problems Adolescence; Educational setting; Violence prevention; Gender issues

Online: 22 September 2023 (13:15:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.0017.v1

The Assessment of Burn Severity and Monitoring of Recovery Process of Wildfire in Mongolia

Battsengel Vandansambuu, Byambakhuu Gantumur, Falin Wu, Oyunsanaa Byambasuren, Sainbuyan Bayarsaikhan, Narantsetseg Chantsal, Nyamdavaa Batsaikhan, Yuhai Bao, Batbayar Vandansambuu, Munkh-Erdene Jimseekhuu

Subject: Environmental And Earth Sciences, Geography Keywords: Wildfire; Burn severity; Vegetation recovery; Sentinel-2; Eastern Mongolia

Online: 1 September 2023 (07:17:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202304.0515.v1

Identification of Hepatic Metabolites of [¹⁸F]Flumazenil and Evaluation of its Application in Neuroimaging

Wei-Hsi Chen, Chuang-Hsin Chiu, Shiou-Shiow Farn, Kai-Hung Cheng, Yuan-Ruei Huang, SHIH-YING LEE, Yao-Ching Fang, Yu-Hua Lin, Kang-Wei Chang

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Flumazenil; LC-QqQ MS; Metabolism; r-aminobutyric acid receptor antagonist; benzodiazepine receptors

Online: 18 April 2023 (10:29:26 CEST)

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Preprint REVIEW | doi:10.20944/preprints202111.0064.v1

Neurogenic Inflammation: One of the Participants of Migraine and the Contribution of Translational Research

Eleonóra Spekker, Masaru Tanaka, Ágnes Szabó, László Vécsei

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: primary headache; migraine; trigeminal system; neuropeptides; neurogenic inflammation; animal model; inflammatory soup; dura mater; immune system; migraine treatment

Online: 3 November 2021 (08:30:58 CET)

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Preprint ARTICLE | doi:10.20944/preprints202011.0564.v1

Evaluation of Toxic Effects of Hexavalent Chromium on the Yield and Quality of Sorghum

Praveen Kumar

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Chromium; Oxidative stress; Sorghum; Biomass; Toxicity; Adversely; Nutritive; Heavy metal; Tolerant

Online: 23 November 2020 (08:57:45 CET)

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Preprint REVIEW | doi:10.20944/preprints201808.0295.v1

Review of Biomedical Applications of Contactless Imaging of Neonates using Infrared Thermography and Beyond

Abbas K. AlZubaidi, Yahya Ethawi, Georg M. Schmoelzer, Sherif Sherif, Michael Narvey, Molly Seshia

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: NICU; Physio-features; Neonatal imaging; Infrared thermography; Optical coherence tomography; Tissue optics; Near-infrared imaging; Short-wave infrared imaging; Visible light imaging

Online: 17 August 2018 (02:27:17 CEST)

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Preprint REVIEW | doi:10.20944/preprints201807.0533.v1

State and Perspectives of the Concept of Large‐Scale Conditioning of Regional Climate Modelling

Hans von Storch, Leone Cavicchia, Frauke Feser, Delei Li

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: regional modelling; spectral; coastal phenomena; stornms

Online: 27 July 2018 (04:39:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0160.v1

The Intersection of ADHD and Autism: Neurodevelopmental Disorders with Shared Origins and Distinct Trajectories

Richard Murdoch Montgomery

Subject: Biology And Life Sciences, Behavioral Sciences Keywords: ADHD; ASD; neurodevelopmental disorders; comorbidity; genetics; neurobiology; environmental factors

Online: 3 September 2024 (10:35:16 CEST)

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Preprint REVIEW | doi:10.20944/preprints202408.1436.v1

Silicon-, Silica- and, Silicate-Toothpastes for Remineralization and Repair of Teeth: A Scoping Review

FABIO CORREIA SAMPAIO, Andressa Feitosa Bezerra de Oliveira, Nayanna Lana Soares Fernandes, Ana Carolina Cheron Gentile, Giovanna Bueno Marinho, Marcelo José Strazzeri Bönecker, Marco Aurelio Benini Paschoal, Paulo Henrique Perlatti D’Alpino, Fabiano Vieira Vilhena

Subject: Chemistry And Materials Science, Biomaterials Keywords: Silicon, silica, silicate, bioactive, toothpastes, dental caries, dentin hypersensitivity

Online: 20 August 2024 (13:42:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0025.v1

Integration of Solar Energy and Agriculture: Agrivoltaic Systems for Sustainable Food and Energy Production

Chris Bell, Ayoolu Olukemi, Abram Gracias

Subject: Engineering, Other Keywords: integration of solar energy; agriculture: agrivoltaic systems; sustainable food; energy production

Online: 1 August 2024 (13:27:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0031.v1

Ensuring Quality Medicine: A Comprehensive Overview of EMA and DGDA's History, Structure, and Functions.

Rashed Ahmed

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: EMA; DGDA; Drug Regulatory Authorities; Manufacturing Guidelines; Quality Medicine; Good Laboratory Practice; cGMP; GMP; GLP; IPQC; QC; QA; Quality Control; Quality Assurance; Current Good Manufacturing Practice; Good Manufacturing Practice

Online: 1 August 2024 (11:15:43 CEST)

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The research article provides an in-depth analysis of the European Medicines Agency (EMA) and the Directorate General of Drug Administration (DGDA), focusing on their historical development, organizational structures, and functional roles in ensuring the quality and safety of pharmaceuticals. The study highlights the origins of drug regulation, tracing back to the early 19th century in the United States with the establishment of the Food and Drug Administration (FDA), and discusses the evolution and significance of drug regulatory bodies worldwide. The EMA and DGDA are scrutinized for their efforts in maintaining high standards for drug approval, monitoring clinical trials, and managing post-marketing surveillance to prevent adverse drug reactions (ADRs). The EMA’s role in coordinating with EU member states on pharmacovigilance and the DGDA’s initiatives in Bangladesh, including the implementation of a nationwide drug database and pharmacovigilance system, are explored in detail. The article concludes by emphasizing the essential role of these regulatory bodies in safeguarding public health through stringent regulation and continuous monitoring of pharmaceuticals, thereby ensuring that only safe and effective medicines are available to consumers . It also provides an in-depth analysis of the roles, structures, and historical contexts of the European Medicines Agency (EMA) and the Directorate General of Drug Administration (DGDA). It outlines how these regulatory bodies ensure the safety, efficacy, and quality of medicinal products. The EMA, serving the European Union, and the DGDA, operating in Bangladesh, play critical roles in drug approval processes, pharmacovigilance, and maintaining public health standards. By setting rigorous guidelines and monitoring compliance, these agencies help safeguard the health of millions, ensuring that only safe and effective medications are available in the market. The paper underscores the importance of these regulatory bodies in promoting public health and supporting the pharmaceutical industry's development and innovation.

Preprint REVIEW | doi:10.20944/preprints202407.2099.v1

Unveiling the Function and Evolutionary Significance of Carnotaurus Horns: A Morphological and Behavioral Study

Tyler Hu

Subject: Biology And Life Sciences, Life Sciences Keywords: morphological significance; behavioral significance; horns; Carnotaurus sastrei; Late Cretaceous period; fossil specimens; comparative anatomy; biomechanical modeling; evolutionary adaptations; potential functions; cranial structures; species recognition; thermoregulation; intraspecific combat; primary role; species recognition; intimidating rivals; signaling mating readiness; head-butting contests; display of dominance; thermoregulation; ecological context; environmental factors; functional morphology; adaptive strategies; theropod dinosaurs; form and function; evolutionary history; predatory dinosaurs

Online: 25 July 2024 (16:52:00 CEST)

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Preprint REVIEW | doi:10.20944/preprints202407.0081.v1

Remimazolam and its place in the current landscape of procedural sedation and general anesthesia

Basavana Goudra, Matthew Brohan, Janette Brohan

Subject: Medicine And Pharmacology, Anesthesiology And Pain Medicine Keywords: General Anesthesia

Online: 1 July 2024 (13:12:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0518.v1

Algorithm-Literacy as a Subset of Media and Information Literacy: Competences and Design Considerations

Divina Frau-Meigs

Subject: Social Sciences, Education Keywords: Media and Information Literacy; Algorithm-literacy; Artificial Intelligence literacy; competence framework; course design; information; disinformation

Online: 8 April 2024 (10:52:54 CEST)

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Preprint REVIEW | doi:10.20944/preprints202403.1292.v1

A Review of Recent Curcumin Analogues and Their Antioxidant, Anti-inflammatory and Anticancer Activities

Kirandeep Kaur, Ahmad K. Al-Khazaleh, Deep Jyoti Bhuyan, Feng Li, Chun Guang Li

Subject: Biochemistry And Molecular Biology, Biology And Life Sciences Keywords: curcumin; modification; anti-inflammatory; antioxidant; anticancer, curcumin analogues

Online: 21 March 2024 (14:07:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0368.v1

Simultaneous Synthesis of Single and Multiple Contaminants Water Networks Using LINGO and Excel Software

Abeer M. Shoaib, Amr A. Atawia, Mohamed H. Hassanean, Abdelrahman G. Gadallah, Ahmed A. Bhran

Subject: Engineering, Chemical Engineering Keywords: Wastewater networks; Multiple contaminants; Mathematical model; Optimization

Online: 7 March 2024 (08:17:53 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.1971.v1

Societal Factors Constraining the Control of COVID-19 and Mosquito and Tick-Borne Diseases

Ranjan Ramasamy

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Aedes aegypti; Aedes albopictus; Anopheles culicifacies; Anopheles stephensi; Borreliosis; Dengue; Climate change; COVID-19; Lyme disease; Malaria; Salinity adaptation in mosquito vectors; Serodiagnosis; Tick-borne relapsing fever; Vaccines

Online: 29 January 2024 (04:35:25 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.1825.v1

Variability and Error in Measurement of Infant Formula Powder and Water: An Experimental Study

Richard R. Rosenkranz*, Ana Gonzalez-Alvarez, Chris Acosta, Andrew Hooyman, Jose R. Hidalgo, CindyRomina Ballesteros Paniagua, Sara K. Rosenkranz

Subject: Medicine And Pharmacology, Dietetics And Nutrition Keywords: infant; formula; feeding; breastfeeding; bottle feeding; over-feeding; measurement; home nutrition support; health information; childhood obesity

Online: 25 January 2024 (10:10:56 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.1281.v1

Probabilistic Forecasting of Lightning Strikes over Continental US and Alaska: Model Development and Verification

Ned Nikolov, Phillip Bothwell, John Snook

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: lightning; model; logistic regression; forecast; prediction; wildfire; probability

Online: 17 January 2024 (08:38:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.0896.v1

Antioxidant and Anti-inflammatory Activity of Carrot Extracts Treated by High Temperature and Pressure

Yun Jo Jung, Yeon Jae Jo, Tae Myoung Kim, Yun-Bae Kim, Junsoo Lee, Heon Sang Jeong

Subject: Biology And Life Sciences, Food Science And Technology Keywords: Carrot; Antioxidant; Anti-inflammatory; High temperature and pressure treatment; Cytokine

Online: 11 January 2024 (11:28:19 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.0612.v1

Development of BVLOS and Night Flight Safety Criteria through VLOS and Night Flight Testing

Gyou Beom Kim, Jung Hoi Jin, Hee Jeong Choi, In Je Cho

Subject: Engineering, Aerospace Engineering Keywords: BVLOS; VLOS; night flight; UAV; drone

Online: 8 January 2024 (09:43:57 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.0305.v1

The Effect of Supraharmonic Distortion in MV and LV AC Grids and Derived Limits

Andrea Mariscotti, Alessandro Mingotti

Subject: Engineering, Electrical And Electronic Engineering Keywords: Accuracy; Aging; Distortion; Disturbance; Power losses; Power quality; Supraharmonics

Online: 4 January 2024 (03:22:08 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.2173.v1

Acetamiprid Exposure-Induces Molecular and Structural Changes in Liver and Kidney Tissues of Rats

Annu Phogat, Jagjeet Singh, Reena Sheoran, Arun Hasanpuri, Vijay Singh, Vijay Kumar, Chandra Prakash, Vinay Malik

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Acetamiprid; apoptosis; toxicity; histopathology; oxidative stress

Online: 28 December 2023 (14:51:51 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.1843.v1

Preparative and Catalytic Properties of MoVI Mononuclear and Metallosupramolecular Coordination Assemblies Bearing Hydrazonato Ligands

Mirna Mandarić, Edi Topić, Dominique Agustin, Jana Pisk, Višnja Vrdoljak

Subject: Chemistry And Materials Science, Other Keywords: molybdenum; hydrazone; metallosupramolecular; dinuclear; metallacycles; polymers; epoxidation; cyclooctene; catalysis; DFT

Online: 25 December 2023 (11:24:35 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.1808.v1

Novel Piperazine and Morpholine Derivatives: Mass Spectrometry Characterization and Evaluation of Their Antimicrobial Properties

Maria Assunta Acquavia, Maria Grazia Bonomo, Giuliana Bianco, Giovanni Salzano, Carmine Gaeta, Patrizia Iannece, Angela Di Capua, Federica Giuzio, Carmela Saturnino

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: piperazine/morpholine derivatives; HRMS; MSn; structural characterization; antimicrobial activity.

Online: 25 December 2023 (08:20:57 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.1199.v1

Did the Pandemic Affect the Quality and Level of Knowledge and Performance (Case Study)

Snezhana Boycheva Dineva, Apostol Todorov, Vasil Hristov, Krasimir Geordiev, Svetoslav Atanasov

Subject: Social Sciences, Education Keywords: education; e-learning; COVID – pandemic; post-pandemic; assessments

Online: 15 December 2023 (14:50:14 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints202312.0826.v1

Theoretical Exploration of Amentoflavone and Bilobetin Interactions with BPIFB4: Implications for Longevity and Cardioprotection

IVAN VITO FERRARI

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: LAV-BPIFB4; Amentoflavone; Bilobetin; Docking analysis; pKCSM

Online: 12 December 2023 (10:54:43 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0832.v1

Characterization and Analysis of Iron Ore Tailings Sediments and Application Possibilities in Earthen Construction

Sofia Araujo Lima Bessa, Marlo Duarte, Gabriela Lage, Isabela Karoline Mendonça, Roberto Galery, Rochel Lago, Ana Paula Texeira, Fernando Lameiras, Maria Teresa Aguilar

Subject: Engineering, Civil Engineering Keywords: mining wastes; rammed earth; toxicity; mechanical analysis

Online: 12 December 2023 (07:29:49 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0784.v1

Hydrochemical Synthesis and Properties of Mercury Sulfide (HgS) and Mercury Selenide (HgSe) Thin Films

Vitalii Stadnik, Ruslana Guminilovych, Martyn Sozanskyi, Pavlo Shapoval, Liliia Deva

Subject: Chemistry And Materials Science, Surfaces, Coatings And Films Keywords: mercury sulfide; mercury selenide; thin films; chemical deposition

Online: 12 December 2023 (05:17:13 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0564.v1

Bridging Digital Competence and Sustainability: Unveiling the Synergistic Potential of Design and Maker Education

Noble Po-kan Lo

Subject: Social Sciences, Education Keywords: maker education; green digital skills; problem-solving; innovation; creativity; engagement; sustainable education

Online: 8 December 2023 (08:31:01 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0569.v1

Alpha-Synuclein Aggregation and Spread: Implications for the Pathology and Progression of Neurodegenerative Diseases

Alin Bose Johnson, Niharika Modi, Krithik N. Kamath, Raman Rajeshkumar, Vasanth Raj Palanimuthu

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: neurodegenerative diseases; Lewy bodies; neurodegenerative; A53T mutation

Online: 8 December 2023 (07:47:36 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0376.v1

Absorption and Biotransformation of Selenomethionine and Selenomethionine-oxide by Wheat Seedlings (Triticum aestivum L.)

Qi Wang, Siyu Huang, Qingqing Huang, Yao Yu, Huafen Li, Yanan Wan

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: wheat; selenomethionine; selenomethionine-oxide; uptake; Se speciation; interaction

Online: 6 December 2023 (10:39:03 CET)

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Preprint REVIEW | doi:10.20944/preprints202311.2008.v1

Composition, Bioactivities, Safety Concerns, and Impact of Essential Oil on Pets’ and Animals’ Health

Natarajan Sisubalan, Bhagavathi Sundaram Sivamaruthi, Periyanaina Kesika, Chaiyavat Chaiyasut

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: essential oils; chemical constituents; toxicity; pets; safety considerations; bioactivity.

Online: 30 November 2023 (16:53:49 CET)

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Preprint REVIEW | doi:10.20944/preprints202311.1218.v1

Immunosenescence and Cytomegalovirus: Exploring Their Connection in the Context of Aging, Health, and Disease

Ludmila Müller, Svetlana Di Benedetto

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: aging; immunosenescence; cytomegalovirus; inflammaging; CMV latency; COVID-19; SARS-CoV-2; long COVID; age-related diseases

Online: 20 November 2023 (05:14:11 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1053.v1

Pattern and Determinants of Chemical and Drug Overdose Poisoning, Makkah, Saudi Arabia 2018-2019

Ghanim Al-Khattabi

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: pattern; determinants; chemical; drug overdose; poisoning; makkah almukarramah; Saudi Arabia

Online: 16 November 2023 (10:11:22 CET)

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Background: Poisoning is a challenging medical condition facing health care providers, as it usually results in serious outcomes in terms of morbidities or mortalities. Poisoning is a challenging medical condition facing health care providers, as it usually results in serious outcomes in terms of morbidities or mortalities. The lack of or inadequate information about the circumstances, substances and populations at risk are considered barriers to the actual prevention of poisoning and effective intervention strategies in Saudi Arabia. The aim of the current study was to describe the pattern and determinants of chemical and drug overdose poisoning in Makkah.Subjects and methods: All reports of chemical and drug overdose poisoning delivered to the Environmental Health and Occupational Safety Department in Makkah over two years (2018-2019) were reviewed.Results: The total number of cases reported in 2018 was 209 cases, while it reached 42 cases in 2019. The overwhelming majority of the cases were Saudi (91.6%), with a slight predominance of males (57.4%) over females (42.6%). Generally, almost two-thirds of the cases occurred in children below 13 years (61.4%), most of the poisoning cases resulted from drug overdose (63.3%), while 34.7% were chemical poisoning. The most common drug poisoning was attributed to analgesics followed by antiepileptics, antihypertensive drugs, antipsychotics and antimicrobials, while cleaning and detergent agents were the most commonly poisoned chemicals. The majority of these agents were taken by the oral route. Children's chemical poisoning was significantly higher than that in older age groups (p<0.05). All intentional poisoning occurred in adults; the great majority of them (88.9%) used drug overdosing rather than chemical substances.Conclusion and recommendations: The current study results are consistent with most of the previous studies carried out in different regions of Saudi Arabia. Further in-depth studies are needed to elaborate other social and demographic factors associated with chemical and drug overdose poisoning. Public health plans, policies and legislations should be implemented to reduce these factors. Intensive supervision of children is needed. Suicidal poisoning patients should seek psychiatric help to limit the possibility of attempting suicide again in the future. Furthermore, efforts are needed to plan and implement health education programs about the factors proven in the current study to be significantly related to chemical and drug overdose poisoning.

Preprint REVIEW | doi:10.20944/preprints202311.1003.v1

Study on the Impact of Automotive Noise and Vibration on Human Health and Environment

Mariana Ratiu, Mariana Adriana Prichici, Alexandru Rus, Sanda Bogdan, Mircea Bogdan Tataru

Subject: Environmental And Earth Sciences, Sustainable Science And Technology Keywords: automotive; noise; vibration; harshness; human health; environment; sustainability

Online: 15 November 2023 (11:52:15 CET)

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Preprint REVIEW | doi:10.20944/preprints202311.0160.v1

Pyrethrins and Pyrethroids: A Comprehensive Review of Natural Occurring Compounds and Their Synthetic Derivatives

Camelia Hodoșan, Cerasela Elena Gîrd, Mihaela Violeta Ghica, Cristina-Elena Dinu-Pîrvu, Lucica Nistor, Iulius Sorin Bărbuică, Ștefan-Claudiu Marin, Alexandru Mihalache, Lăcrămioara Popa

Subject: Medicine And Pharmacology, Pharmacy Keywords: pyrethrins; pyrethroids; insecticides; terpenoids; pyrethrum.

Online: 2 November 2023 (10:36:10 CET)

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Preprint CASE REPORT | doi:10.20944/preprints202311.0083.v1

Collision Tumors of the Colon and Peritoneum: Signet-Ring Carcinoma and Granular Cell Tumor

Dorela-Codruta Lazureanu, Denisa Anderco, Sorin Dema, Aura Jurescu, Remus Cornea, Octavia Vita, Bogdan Tunescu, Sorina Taban

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: abdominal collision tumors; colon signet-ring carcinoma; peritoneal granular cell tumor

Online: 2 November 2023 (06:51:32 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.1624.v1

Shock-Induced Degradation of Guanosine and Uridine Promoted by Nickel and Carbonate: Potential Applications

Gustavo P. Maia, José Armando Luisa Da Silva, Vânia André, Adelino M. Galvão

Subject: Chemistry And Materials Science, Applied Chemistry Keywords: mechanochemistry; DFT; degradation reactions; Meteorites; Asteroids

Online: 25 October 2023 (09:32:07 CEST)

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Preprint REVIEW | doi:10.20944/preprints202310.1225.v1

Thermal Conductivity and Temperature Dependency of MR Fluids and Application Systems—A Chronologically Review

Seung-Bok Choi

Subject: Engineering, Mechanical Engineering Keywords: magnetorheological fluid; temperature effect; thermal conductivity; field-dependent properties; heat transfer

Online: 19 October 2023 (08:06:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0630.v1

Prevalence of Enterobacteriaceae in Camels, Cattle, and Sheep Carcasses at Slaughterhouses and Butcher Shops

Fahad Al-Asmari, Siddig H. Hamad, Sallah A. Al Hashedi

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: Enterobacteriaceae; Camels; Cattle; Sheep; Slaughterhouses; Butcher Shops; Salmonella; Al-Ahsa

Online: 10 October 2023 (12:21:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.0729.v1

Aspects of Urban Climate Adaptation and Mitigation Plans: The Bologna Case Study and Outcomes

Letizia Cremonini, Teodoro Georgiadis, Marianna Nardino, Federica Rossi, Alessandro Rossi, Giovanna Pinca, Massimiliano Fazzini

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: adaptation; climate change; urban vulnerabilities; population health; resilience; urban regeneration; social acceptance

Online: 12 September 2023 (07:11:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.0585.v1

Evaluating Relative Perceptual Salience of Linguistic and Emotional Prosody in Quiet and Noisy Contexts

Minyue Zhang, Hui Zhang, Enze Tang, Hongwei Ding, Yang Zhang

Subject: Social Sciences, Language And Linguistics Keywords: babble noise; lexical tone; emotional prosody; masking

Online: 8 September 2023 (11:14:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.0197.v1

Noise and Legal Dispute: Applications and Limits of the Italian Stardard UNI/TS 11844

Fabio Serpilli, Samantha Di Loreto, Valter Lori, Sergio Montelpare

Subject: Environmental And Earth Sciences, Pollution Keywords: Intrusive noise; signal detection theory; acoustic standard; acoustic disputes

Online: 4 September 2023 (14:25:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.0055.v1

Rethinking Upskilling and Reskilling in the Age of AI and Automation: A fsQCA Approach

Kelechi Ekuma

Subject: Business, Economics And Management, Human Resources And Organizations Keywords: upskilling, reskilling, AI and automation, skills development, workforce adaptability, fsQCA

Online: 1 September 2023 (10:28:31 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.2157.v1

Target Localization and Grasping of NAO robot Based on YOLOv8 network and Monocular Ranging

Yingrui Jin, Zhaoyuan Shi, Xinlong Xu, Guang Wu, Hengyi Li, Shengjun Wen

Subject: Computer Science And Mathematics, Robotics Keywords: NAO robot; YOLOv8 network; monocular ranging; error compensation model; pose interpolation

Online: 31 August 2023 (09:52:07 CEST)

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Preprint REVIEW | doi:10.20944/preprints202308.2151.v1

Advance in Cell Cultures, Cell Fusion and Cell Splitting of Medicinal and Edible Plant

Fumei Shi, Chao Wang

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Medicinal and edible plants; cell cultures; cell fusion; somatic hybridization; artificial polyploidy induction; cell engineering

Online: 31 August 2023 (07:52:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.2025.v1

Pan-Cancer Profiling of Intron Retention and Its Clinical Significance in Diagnosis and Prognosis

Leihuan Huang, Xin Zeng, Haijing Ma, Yu Yang, Yoshie Akimoto, Gang Wei, Ting Ni

Subject: Biology And Life Sciences, Life Sciences Keywords: intron retention; RNA-seq; cancer; diagnosis; prognosis

Online: 30 August 2023 (14:10:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.1227.v1

Shading Level and Harvest Time Affect the Photosynthetic and Physiological Properties of Basil Varieties

Paria Eskandarzade, Mahboobeh Zare Mehrjerdi, Fardad Didaran, Nazim S. Gruda, Sasan Aliniaeifard

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Chlorophyll fluorescence; harvest time; shading; Controlled Environment Agriculture (CEA); photoinhibition

Online: 17 August 2023 (09:10:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.0671.v1

Modes of Vibration in Basketball Rims and Backboards and the Energy Rebound Testing Device

Daniel James Winarski, Kip P. Nygren, Tyson York Winarski

Subject: Engineering, Mechanical Engineering Keywords: Basketball Rim and Backboard; Modal Analysis; Frequency; Damping

Online: 8 August 2023 (11:52:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.1800.v1

Occurrence, Structure, and Abundance Natural and Artificial of Juglans neotropica Diels in Southern Ecuador

Byron Palacios-Herrera, Santiago Pereira-Lorenzo, Darwin Pucha-Cofrep

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Fruit; forest; ecosystem; wood; native; Ecuador

Online: 26 July 2023 (12:22:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.1380.v1

Sustainable Agricultural Practices for the Production of Aromatic and Medicinal Plants: Evidences and Recommendations

Samia Hamdane, Sara Marcelino, Pedro Dinis Gaspar, Arminda Paço

Subject: Environmental And Earth Sciences, Sustainable Science And Technology Keywords: Aromatic and medicinal herbs; Risk; sustainability; Harvesting; Shelf-life extension; Wastes.

Online: 20 July 2023 (05:17:14 CEST)

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Preprint REVIEW | doi:10.20944/preprints202307.0585.v1

Underwater Image Restoration and Enhancement: A Comprehensive Review of Recent Trends, Challenges, and Applications

Yasmin M. Alsakar, Nehal A Sakr, Shaker El-Sappagh, Tamer Abuhmed, Mohammed Elmogy

Subject: Computer Science And Mathematics, Computer Vision And Graphics Keywords: Underwater image analysis; Underwater image restoration; Underwater image enhancement; Underwater datasets; Underwater image quality evaluation

Online: 10 July 2023 (10:06:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.0205.v1

Measuring Circularity and Impact Reduction Potential of Post-industrial and Post-consumer Recycled Plastics

Anna Schulte, Benjamin Kampmann, Christina Galafton

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Life cycle assessment; LCA; Circular Economy; Indicator; Polypropylene; Recycling; global warming impact; climate change; efficiency; effectiveness; PCR; PIR; environmental assessment

Online: 4 July 2023 (11:13:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.1593.v1

An Exploratory Attitude and Belief Analysis of Ecotourists’ Destination Image Assessments and Behavioral Intentions

Rich Harrill, Alexander Zuñiga-Collazos, Marysol Castillo-Palacio, Lina Marcela Padilla-Delgado

Subject: Business, Economics And Management, Business And Management Keywords: Ecotourism; birdwatching; destination image; destination marketing; Colombia

Online: 22 June 2023 (10:40:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.1062.v1

Phenolic Characterisation of Globe Artichoke Heads and Waste from Vegetatively- and “Seed”-Propagated Genotypes

Anna Bonasia, Giulia Conversa, Corrado Lazzizera, Antonio Elia

Subject: Biology And Life Sciences, Horticulture Keywords: Cynara cardunculus L. subsp. scolymus; Brindisino; Violetto di Foggia; Tempo; Opal; Madrigal; polyphenols; chlorogenic acid; cynarin; luteolin; apigenin.

Online: 14 June 2023 (15:08:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0831.v1

Fabrication and Characterization of Durable Superhydrophobic and Superoleophobic Surfaces on Stainless Steel Mesh Substrates

SAIRA IQBAL

Subject: Engineering, Mechanical Engineering Keywords: durability; self-cleaning; superhydrophobicity; superoleophobicity; wear-resistant

Online: 12 June 2023 (11:51:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0796.v1

Ionic Conductivity of Li6PS5Cl0.5Br0.5 Argyrodite Electrolyte at Different Operating and Pelletizing Pressures and Temperatures

Joshua Dunham, Joshua Carfang, Chan-Yeop Yu, Raziyeh Ghahremani, Rashid Farahati, Siamak Farhad

Subject: Engineering, Energy And Fuel Technology Keywords: All-solid-State Battery; Argyrodite Electrolyte; Li6PS5CL0.5Br0.5; Pelletizing; Pressure; Temperature

Online: 12 June 2023 (08:20:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0342.v1

A Comparative Study of Tumor-Specificity and Neurotoxicity Between 3-Styrylchromones and Anticancer Drugs

Tomoyuki Abe, Hiroshi Sakagami, Shigeru Amano, Shin Uota, Kenjiro Bandow, Yoshihiro Uesawa, Shiori U, Hiroki Shibata, Yuri Takemura, Yu Kimura, Koichi Takao, Yoshiaki Sugita, Akira Sato, Sei-ichi Tanuma, Hiroshi Takeshima

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: chromone derivatives; oral squamous cell carcinoma; tumor-specificity; keratinocyte toxicity; neurotoxicity; signaling pathway

Online: 5 June 2023 (15:45:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0056.v1

Exploring Structural, Electronic, Magnetic, and Transport Properties of 2D Cr, Fe, and Zr Monoborides

Isabel Arias-Camacho, Nevill Gonzalez Szwacki

Subject: Physical Sciences, Condensed Matter Physics Keywords: Transition metal borides; MBenes; Energy conversion and storage; 2D magnets

Online: 1 June 2023 (07:50:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.2259.v1

Planning and Evaluation of Nuclear-Renewable Hybrid Energy Penetration for Marine and Waterfront Applications

Hossam A.Gabbar, Otavio Lopes Alves Esteves

Subject: Engineering, Energy And Fuel Technology Keywords: Marine Vessels; Nuclear-Renewable Hybrid Energy Systems; Waterfront Applications, Seaports, Hydrogen Production, Energy Efficiency.

Online: 31 May 2023 (14:02:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.2215.v1

Analytical Solution and Numerical Simulation of Heat Transfer in Cylindrical and Spherical Shaped Bodies

Humam Kareem Jalghaf, Endre Kovács, Imre Ferenc Barna, László Mátyás

Subject: Computer Science And Mathematics, Computational Mathematics Keywords: Numerical time integration; diffusion equation; heat equation; cylindrical coordinates; spherical coordinates; unconditional stability

Online: 31 May 2023 (09:53:08 CEST)

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Preprint REVIEW | doi:10.20944/preprints202305.1454.v1

Relevance of Genetic Identification and Kinship Analysis in Human and Natural Catastrophes – A Review

Alejandra Real-Picado, Luis Diaz, Cláudia Gomes

Subject: Medicine And Pharmacology, Other Keywords: Catastrophes; Genetic identification; Kinship analysis; DNA degradation

Online: 22 May 2023 (03:01:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.1189.v1

Chemical and Biological Characterization of Green and Processed Coffee Beans from Coffea arabica Varieties

Javier Gallardo-Ignacio, Anislada Santibáñez, Octavio Oropeza-Mariano, Ricardo Salazar, Rosa Mariana Montiel-Ruiz, Sandra Cabrera-Hilerio, Manasés Gonzáles-Cortazar, Francisco Cruz-Sosa, Pilar Nicasio-Torres

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: antioxidant; chlorogenic acid; caffeine; cytotoxicity; melanoidins

Online: 17 May 2023 (04:58:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.1079.v1

Production and Quality of West Indian Cherry under Salt Stress and NPK Fertilization Combinations

Antonio Manoel da Silva Filho, Hans Raj Gheyi, Alberto Soares De Melo, André Alisson Rodrigues da Silva, Semako Ibrahim Bonou, Lumara Tatiely Santos Amadeu, Rener Luciano de Souza Ferraz, Patrícia da Silva Costa, Lucia Helena Garófalo Chaves, Rossana Maria Feitosa de Figueirêdo

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Malpighia emarginata; water salinity; fertilization management

Online: 16 May 2023 (04:37:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.0765.v1

Radiation Beam Width and Beam Direction Electronical Control of Transparent and Compact Vivaldi Antennas

Amani Cherif, Himdi Mohamed, Castel Xavier, Simon Quentin, Dakhli Saber, Choubani Fethi

Subject: Physical Sciences, Optics And Photonics Keywords: Optical transparency; Vivaldi antenna; Active antenna; Reconfigurability; Wide band frequency

Online: 10 May 2023 (14:37:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.0053.v1

Raman Spectrocopic and Surface-Enhanced Raman Spectrocopic Analyses of Normal Blood and Abnormal Blood

Song-Jeng Huang, Jun-Han Lan, Chao-Ching Chiang, Fang-Yuh Lo, Kung-Chia Young

Subject: Engineering, Bioengineering Keywords: blood testing, biological information; hemoglobin; Raman spectroscopy; surface-enhanced Raman spectroscopy (SERS)

Online: 2 May 2023 (04:14:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202304.0955.v1

Strategic Development and Internationalization of Cultural Industry with Virtual Reality and Augmented Reality Technologies

Antonios Kargas, Georgios Loumos

Subject: Computer Science And Mathematics, Software Keywords: strategic development; Business Internationalization; Cultural Industry; Virtual Reality; Augmented Reality

Online: 26 April 2023 (04:20:36 CEST)

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Preprint REVIEW | doi:10.20944/preprints202304.0916.v1

Diagnostic and Prognostic Roles of Procalcitonin and Other Markers in Pneumonia: A Literature Update

Sedat OZBAY, Mustafa AYAN, Ozgur Karcioglu

Subject: Medicine And Pharmacology, Emergency Medicine Keywords: pneumonia; bacteremia; sepsis; procalcitonin; diagnosis; biomarker; outcome; antibiotic stewardship

Online: 25 April 2023 (10:00:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202304.0561.v1

The Impact of Bilirubin on 7α- and 7β- Hydroxysteroid Dehydrogenases: Spectra and Docking Analysis

Qingzhi Ji, Jiamin Chen, Luping Zhu, Ruiyao Wang, Bochu Wang

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Bilirubin; 7α- and 7β-hydroxysteroid dehydrogenases; Activity; Inhibition

Online: 19 April 2023 (07:35:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202303.0332.v1

Associated Lie Algebras of One-Variable and Bivariate Hermite Polynomials and New Generating Functions

Manouchehr Amiri

Subject: Computer Science And Mathematics, Mathematics Keywords: Bivariate Hermite Polynomial; Lie Algebra; Baker-Campbell-Hausdorff formula; generating function; sl (2,R) algebra

Online: 20 March 2023 (02:18:57 CET)

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Preprint REVIEW | doi:10.20944/preprints202302.0448.v1

Aidan McGinnis, Ru-Rong Ji

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: dorsal root ganglia; fatty acids; gliopathy; nerve injury; spinal cord

Online: 27 February 2023 (06:35:32 CET)

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Preprint ARTICLE | doi:10.20944/preprints202301.0399.v1

Isolation, and Enumeration of Bifidobacteria from Breast-Fed, Formula-Fed Infants and Antibiogram Development.

Rajagopal Kammara, Anagha Nellikka

Subject: Biology And Life Sciences, Food Science And Technology Keywords: B. adolescentis; Antibiogram; f6ppk; xfp; RFLP

Online: 23 January 2023 (07:03:40 CET)

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Preprint ARTICLE | doi:10.20944/preprints202212.0412.v1

New Framework for Assembly Digitalization and Traceability Using Smart Contracts and Bill of Assembly

Yuval Cohen, Shai Rozenes

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: Smart Assembly; Smart contract; Assembly line; Assembly 4.0; Assembly system; Block-chain; Digital twin; Industry 4.0; Smart manufacturing

Online: 22 December 2022 (03:24:09 CET)

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Preprint ARTICLE | doi:10.20944/preprints202212.0165.v1

The Association between Screening for Colorectal Cancer and Measures of Mental and Physical Health.

yiting gong, Louise Keogh, Carlene Wilson, Mark Jenkins

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Colorectal cancer screening; SF-12

Online: 9 December 2022 (01:08:54 CET)

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Preprint ARTICLE | doi:10.20944/preprints202211.0377.v1

Solid Particle Erosion of Unfilled and Filled Epoxy Resin at Room and Elevated Temperatures

Maxim Mishnev, Alexander Korolev, Dmitrii Ulrikh, Anna Gorechneva, Denis Sadretdinov, Danila Grinkevich

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: solid particle erosion; epoxy resin; thermoset polymers; fly-ash; filled compound; elasticity modu-lus; bending strength

Online: 21 November 2022 (06:38:01 CET)

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Preprint ARTICLE | doi:10.20944/preprints202210.0182.v1

Isolation and Identification of Arsenic Hyper-Tolerant and Plant Growth Promoting Bacterium from Soil

Debjani Mandal, Mina Aghababaei, Sadhan Kr Das, Santanu Majumder, Debashis Chatterjee, Abhishek Basu

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Arsenic hyper-tolerant bacterium; 16S rDNA sequencing; Microbacterium paraoxydans; Arsenic bioremediation; Plant growth promoting bacterium

Online: 13 October 2022 (02:01:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202210.0095.v1

Checklist of Helminth Parasites and Epizoites in Common Dolphins from Coastal Peru and Ecuador

Joanna Alfaro-Shigueto, Koen Van Waerebeek, Julio C. Reyes, Marie-Francoise Van Bressem, Jorge Samaniego, Fernando Félix, Natalia Fraija-Fernández

Subject: Biology And Life Sciences, Parasitology Keywords: helminths; parasitology; Delphinus; common dolphins; Southeast Pacific Ocean; Peru; Ecuador

Online: 8 October 2022 (05:39:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202209.0130.v1

Sociodemographic and Economic Profile of Bicycle-Taxi Riders and Revenue Modelling in Quelimane, Mozambique

Arlete Freitas Jone, Solomon Runhungwe, Joao Luis Ferrao

Subject: Business, Economics And Management, Econometrics And Statistics Keywords: bicycle taxi; profile; sociodemographic

Online: 9 September 2022 (07:03:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202209.0045.v1

Development and Testing of an Integrated Energy-Efficient Vehicle Speed and Traffic Signal Controller

Hao Chen, Hesham Rakha

Subject: Engineering, Civil Engineering Keywords: Traffic signal congrol; vehicle control; integrated control

Online: 5 September 2022 (04:47:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202208.0511.v1

Phytochemical Composition and Antibacterial Activity of Zingiber cassumunar Roxb. against Agricultural and Foodborne Pathogens

Maha A. Alshiekheid, Yheni Dwiningsih, Amal Abdullah Sabour, Jawaher Alkahtani

Subject: Biology And Life Sciences, Plant Sciences Keywords: Zingiber cassumunar Roxb.; essential oils; microencapsulated products; antibacterial activity; agricultural pathogens; foodborne pathogens; gram-positive bacteria; gram-negative bacteria

Online: 30 August 2022 (07:02:54 CEST)

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Zingiber cassumunar Roxb. is a powerful medicinal plant that has been used as traditional medicine to cure respiratory problems, pain, and inflammation in China, Indonesia, Thailand and other Asian countries by using the crude extracts. The objective of this research is to identify phytochemical composition of Z. cassumunar Roxb. and to analyze antibacterial activity of crude extract, purified compounds, and their microencapsulated products of Rhizome Z. cassumunar Roxb. Identification of phytochemical composition in crude extract of rhizome Z. cassumunar Roxb. was achieved by chromatography-mass spectrophotometer. The major phytochemical composition in crude extract of Z. cassumunar Roxb. is essential oils, including terpinen4-ol (37.7%), β-pinene (20.8%), and (E)-1-(3,4-dimethoxyphenyl)but-1-ene (13.3%). Crude extract of Z. cassumunar Roxb. was purified with silica gel flash column chromatography, resulting two purified compounds. The antibacterial activity of crude extract, purified compounds, and their microencapsulated products of Rhizome Z. cassumunar Roxb. were evaluated against agricultural and foodborne pathogens by using disc agar diffusion and broth microdilution techniques. All of the samples studied (crude extracts, purified compounds, and microencapsulated of Z. cassumunar Roxb.) were effective against all the bacteria. Based on the results of the disc-diffusion assay suggested that amongst the samples studied, purified compounds (compound 1 and 2) and microencapsulated purified compounds (compound 1 and 2) exhibited more effective against all the bacteria compared to the crude extracts. Antibacterial activity of the rhizome of Z. cassumunar Roxb. was contributed mainly by the essential oils components as the active compounds. Gram-negative bacteria (X. oryzae, X. translucens, Pseudomonas spp, E. coli, and S. typhimurium) appeared to the most resistant to the crude extracts, purified compounds, and microencapsulated of Z. cassumunar Roxb. compared to the gram-positive bacteria (S. aureus, B. cereus, and L. monocytogenes). Microencapsulated of the tested samples (crude extract, purified compound 1, and purified compound 2) of the rhizome Z. cassumunar Roxb. exhibited high antibacterial activity with no significantly different with the tested samples without microencapsulation. These results suggest potential antibacterial properties of Z. cassumunar Roxb., which useful for agricultural plant health, food preservation, natural therapies, and pharmaceuticals.

Preprint REVIEW | doi:10.20944/preprints202207.0326.v1

Self-Enhancement and the Medial Prefrontal Cortex: the Convergence of Clinical and Experimental Findings

Saeed Yasin, Anjel Fierst, Harper Keenan, Amelia Knapp, Katrina Gallione, Tessa Westlund, Sydney Kirschner, Sahana Vaidya, Christina Qiu, Audrey Rougebec, Elodie Morss, Jack Lebiedzinski, Maya Dejean, Julian Paul Keenan

Subject: Social Sciences, Behavior Sciences Keywords: Frontal Cortex; PFC; Self-enhancement; Self-deception; SE

Online: 21 July 2022 (10:55:56 CEST)

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Preprint TECHNICAL NOTE | doi:10.20944/preprints202206.0008.v1

A Novel Approach for the Global Detection and Nowcasting of Deep Convection and Thunderstorms

Richard Müller, Axel Barleben, Stéphane Haussler, Matthias Jerg

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Thunderstorms; Cumulonimbus; Convection; Nowcasting; Lightning

Online: 1 June 2022 (08:25:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202204.0107.v1

On the Redox-Activity and Health-Effects of Atmospheric Primary and Secondary Aerosol: Phenomenology

Francesca Costabile, Stefano Decesari, Roberta Vecchi, Franco Lucarelli, Gabriele Curci, Dario Massabò, Matteo Rinaldi, Maurizio Gualtieri, Emanuela Corsini, Elena Menegola, Silvia Canepari, Lorenzo Massimi, Stefania Argentini, Maurizio Busetto, Gianluca Di Iulio, Luca Di Liberto, Marco Paglione, Igor Petenko, Mara Russo, Angela Marinoni, Gianpietro Casasanta, Sara Valentini, Vera Bernardoni, Federica Crova, Gianluigi Valli, Alice Corina Forello, Fabio Giardi, Silvia Nava, Giulia Pazzi, Paolo Prati, Virginia Vernocchi, Teresa La Torretta, Ettore Petralia, Milena Stracquadanio, Gabriele Zanini, Gloria Melzi, Emma Nozza, Martina Iulini, Donatella Caruso, Lucia Cioffi, Gabriele Imperato, Flavio Giavarini, Maria Battistoni, Francesca Di Renzo, Maria Agostina Frezzini, Cinzia Perrino, Maria Cristina Facchini

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: atmospheric aerosol; chemical composition; secondary aerosol; source apportionment; ultrafine particles; oxidative potential; exposure; toxicology; forecasting; micrometeorology

Online: 12 April 2022 (09:54:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202111.0398.v1

Targeted Action and Molecular Interactions of Sarcin and Thionin With Aspergillosis Causing Aspergillus fumigatus

Ramya Ravindhiran, Ramya Krishnamurthy, Karthiga Sivarajan, JothiNayaki Sekar, Kumarappan Chidambaram, Kavitha Dhandapani

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: Aspergillus giganteus; Aspergillosis; Antagonism; Sarcin; ADMET; GC-MS

Online: 22 November 2021 (13:56:36 CET)

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Preprint ARTICLE | doi:10.20944/preprints202110.0114.v1

The Relativistic and the Hidden Momentum of Minkowski and Abraham in Relativistic Energy Wave

D.S. Cardoso

Subject: Physical Sciences, Optics And Photonics Keywords: Photon; Relativistic Energy Wave; Abraham Momentum; Minkonwski Momentum; Relativistic Photon Ignition; Apparent Doppler; Orbital Angular Momentum; OAM

Online: 7 October 2021 (10:45:58 CEST)

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