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Preprint ARTICLE | doi:10.20944/preprints202307.0176.v1

Evaluation of the Early Intervention Physiotherapist Framework for Injured Workers in Victoria, Australia: Data Analysis Follow-up

Hadi Akbarzadeh Khorshidi, Uwe Aickelin, Andrea De Silva

Subject: Public Health And Healthcare, Physical Therapy, Sports Therapy And Rehabilitation Keywords: Early Intervention; Return to Work; Physiotherapists; Workers’ Compensation; Evaluation

Online: 4 July 2023 (09:43:06 CEST)

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Purpose: This study evaluates the performance of the Early Intervention Physiotherapist Framework (EIPF) for injured workers. This study provides a proper follow-up period (3 years) to examine the impacts of the EIPF program on injury outcomes such as return to work (RTW) and time to RTW. This study also identifies the factors influencing the outcomes. Methods: The study was conducted on data collected from compensation claims of people who were injured at work in Victoria, Australia. Injured workers who commenced their compensation claims after the first of January 2010 and had their initial physiotherapy consultation after the first of August 2014 are included. To conduct the comparison, we divided the injured workers into two groups: physiotherapy services provided by EIPF-trained physiotherapists (EP) and regular physiotherapists (RP) over the three-year intervention period. We used three different statistical analysis methods to evaluate the performance of the EIPF program. We used descriptive statistics to compare two groups based on physiotherapy services and injury outcomes. We also completed survival analysis using Kaplan-Meier curves in terms of time to RTW. We developed univariate and multivariate regression models to investigate whether the difference in outcomes achieved after adjusting for significantly associated variables. Results: The results showed that physiotherapists in the EP group on average dealt with more claims (over twice as many) than those in the RP group. Time to RTW for the injured workers treated by the EP group was significantly lower than for those who were treated by the RP group, indicated by descriptive, survival and regression analyses. Earlier intervention by physiotherapists led to earlier RTW. Conclusion: This evaluation showed that the EIPF program achieved successful injury outcomes three years after implementation. Motivating physiotherapists to intervene earlier in the recovery process of injured workers by initial consultation helps to improve injury outcomes.

Preprint REVIEW | doi:10.20944/preprints202305.1773.v1

A Review of a Candidates for a Validation Data Set for High-Assay Low-Enrichment Uranium Fuels

Mark D. DeHart, John D. Bess, Germina Ilas

Subject: Engineering, Energy And Fuel Technology Keywords: HALEU; High-Assay LEU; Advanced Reactors; Validation; DOE; NRC

Online: 25 May 2023 (08:45:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.0634.v1

Multivariate Curve Resolution Methodology Applied to the ATR-FTIR Data for Adulteration Assessment of Virgin Coconut Oil

Michele De Luca, Giuseppina Ioele, Fedora Grande, Maria Antonietta Occhiuzzi, Martina Chieffallo, Antonio Garofalo, Gaetano Ragno

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: virgin coconut oil; oil adulteration; Fourier transform infrared; multivariate curve resolution; genetic algorithm; control chart.

Online: 9 May 2023 (10:22:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202212.0567.v1

Addressing the Selection Bias in Voice Assistance: Training Voice Assistance Model in Python with Equal Data Selection

Kashav Piya, Srijal Shrestha, Cameran Frank, Estephanos Jebessa, Tauheed Khan Mohd

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Voice Assistance, Machine Learning, Virtual Assistance, Artificial Intelligence, Selection Bias, Sample Population, Python 3.10, Pyttsx3, PyTorch, JSON

Online: 30 December 2022 (02:12:34 CET)

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Preprint ARTICLE | doi:10.20944/preprints202211.0344.v1

Deciphering Tumour Microenvironment of Liver Cancer through Deconvolution of Bulk RNA-seq Data with Single-cell Atlas

Shaoshi Zhang, Wendi Bacon, Maikel P. Peppelenbosch, Folkert van Kemenade, Andrew P. Stubbs

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: liver cancer; tumour microenvironment; deconvolution

Online: 18 November 2022 (02:30:26 CET)

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Preprint REVIEW | doi:10.20944/preprints202211.0177.v1

Monoclonal Antibodies Against Calcitonin Gene-related Peptide for Migraine Prophylaxis: A Systematic Review of Real-world Data

Antun Pavelic, Christian Wöber, Franz Riederer, Karin Zebenholzer

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Real-world; Erenumab; Galcanezumab; Fremanezumab; Eptinezumab; pharmacoepidemiology; effectiveness; tolerability; safety; treatment pause; switching

Online: 9 November 2022 (11:51:21 CET)

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Preprint ARTICLE | doi:10.20944/preprints202208.0019.v1

Mode Choice of City Tourists: Discrete Choice Modeling Based on Survey Data from A Major German City

Jonas Harz, Carsten Sommer

Subject: Engineering, Civil Engineering Keywords: discrete choice modeling; mode choice; travel behavior; city tourism; sustainable tourism; revealed preference data

Online: 1 August 2022 (10:13:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202204.0086.v1

A Comprehensive Approach for Floodplain Mapping Through Identification of Hazard Using Publicly Available Data Sets Over Canada

Mohit Prakash Prakash Mohanty, Slobodan P. Simonovic

Subject: Engineering, Civil Engineering Keywords: Flood hazard; CaMa-Flood; Flood Map Viewer; Floodplain mapping; Flood risk; North American Regional Reanalysis; Property exposure

Online: 11 April 2022 (03:35:28 CEST)

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Flood events and their associated damages have escalated significantly in the last few decades. To add to the gruesome situation, many reports and studies warn that flood risk would aggravate significantly in future periods due to significant alterations in the climate patterns and socio-economic dynamics. Floodplain mapping is looked upon as a viable option to tackle this global issue as it provides both quantitative and qualitative information on flood dynamics. Moreover, with the increasing availability of global data and enhancement in computational simulations, it has become easier to simlate flooding patterns at large scales. This study deter-mines the usability of publicly available datasets in capturing flood hazards over Canada. Run-off data set from the North American Regional Reanalysis (NARR), along with a few other rele-vant inputs are fed to CaMa-Flood, a robust global hydrodynamic model to generate flooding patterns for 1 in 100 and 1 in 200-yr return period events over Canada . The simulated maps are compared and validated with the existing maps of a few flood-prone regions in Canada, thereby establishing their performance over both regional and country-scale. Later, the simulated flood-plain maps are used in conjunction with property related information at 34 cities (within the top 100 populous cities in Canada) to determine the degree of exposure due to flooding in 1991, 2001, and 2011. The results indicate that around 80 percent of inundated spots belong to high and very-high hazard classes in a 200-yr event, which is roughly 4 percent more than simulated for 100-yr event. NARR derived floodplain maps perform very well while compared over the six flood-prone regions. While analyzing the exposure of properties to flooding, we notice an in-crease in the number during the last three decades, with the maximum rise observed in Toronto, followed by Montreal, and Edmonton. To disseminate the extensive flood-related information, a web-based public tool, Flood Map Viewer (http://www.floodmapviewer.com/) is developed. The development of the tool was motivated by the commitment of the Canadian government to provide $63 M over the next three years for the completion of flood maps for higher-risk areas. The study reaches out to demonstrate how publicly available datasets can be utilized with a lesser degree of uncertainty in representing flooding patterns over large regions. The flood re-lated information derived from the study can be used along with vulnerability for quantifying flood risk, which will help in developing appropriate pathways for resilience building for long-term sustainable benefits.

Preprint ARTICLE | doi:10.20944/preprints202107.0649.v1

A Smart Health (sHealth) Centric Method Toward Estimation of Sleep Deficiency Severity from Wearable Sensor Data Fusion

M. J. Rahman, Bashir I. Morshed, Chrysanthe Preza

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: Sleep deficiency severity; Monte-Carlo Feature Selection; Bayesian Regression; Artificial Neural Network; Smart Health; Wearables

Online: 29 July 2021 (11:36:05 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202011.0441.v1

SARS-Cov-2 Interactome with Human Ghost Proteome: A Neglected World Encompassing a Wealth of Biological Data

Cardon Tristan, Isabelle Fournier, Salzet Michel

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: Sars-Cov-2; Proteomic,; Ghost proteome,; Alternative proteins,; AltOrf.; interactomic; drug repurposing

Online: 16 November 2020 (17:50:19 CET)

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Preprint ARTICLE | doi:10.20944/preprints202011.0438.v1

Analysing Temporal Variability in Inventory Data for Life Cycle Assessment: Implications in the Context of Circular Economy

Sayyed Shoaib-ul-Hasan, Malvina Roci, Farazee Mohammad Abdullah Asif, Niloufar Salehi, Amir Rashid

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: Life cycle assessment; circular economy; multiple product life cycles; temporal variability; life cycle inventory; emission intensity

Online: 16 November 2020 (17:24:26 CET)

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Preprint ARTICLE | doi:10.20944/preprints202010.0255.v1

Characterization of Pathogen Air-Borne Inoculum Density by Information Theoretic Analysis of Spore Trap Time Series Data

Robin A Choudhury, Neil McRoberts

Subject: Biology And Life Sciences, Plant Sciences Keywords: time series; entropy; average mutual information; stochastic process; deterministic dynamics

Online: 12 October 2020 (16:12:14 CEST)

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Working Paper ARTICLE

Time for a Change: Considering Regimen Changes in Analyses of Observational MDR/RR-TB Treatment Cohort Data

Molly Franke, Carole Mitnick

Subject: Medicine And Pharmacology, Clinical Medicine Keywords: tuberculosis; epidemiology; drug-treatment; resistance; analysis

Online: 13 September 2020 (11:20:13 CEST)

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Preprint CASE REPORT | doi:10.20944/preprints202004.0531.v1

Data Forensic Determination of the Accuracy of International COVID-19 Reporting: Using Zipf's Law for Pandemic Investigation

Aamo Iorliam, Anthony T.S. Ho, Santosh Tirunagari, David Windridge

Subject: Medicine And Pharmacology, Other Keywords: Zipf's law; COVID-19; Pandemics

Online: 30 April 2020 (13:49:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202003.0109.v1

An Analysis of Time-Varying Crowding on Subway Platforms using AFC Data in Seoul Metropolitan Subway Network

Seongil Shin Shin, Sangjun Lee

Subject: Computer Science And Mathematics, Information Systems Keywords: Automated Fare Collection (AFC); Smart Card; Crowding; Practical Waiting Area; Subway Station Platform; Time-Varying; Late-Night Peak

Online: 6 March 2020 (09:02:01 CET)

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Preprint ARTICLE | doi:10.20944/preprints201810.0139.v1

Dynamic Measurements with the Bicone Interfacial Shear Rheometer: Numerical Bench-Marking of Flow Field Based Data Processing

Pablo Sánchez-Puga, Javier Tajuelo Rodríguez, Juan Manuel Pastor, Miguel Ángel Rubio

Subject: Physical Sciences, Condensed Matter Physics Keywords: interfacial rheology; interfacial shear rheometer; bicone interfacial rheometer; flow field based data processing

Online: 8 October 2018 (11:15:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201801.0139.v1

Cave Pearl Data Logger – A flexible Arduino-based Logging Platform for Long-Term Monitoring in Harsh Environments

Patricia A. Beddows, Edward K. Mallon

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: data logger; environmental monitoring network; open source; submersible; under-water; critical zone observatory; cave; Yucatan Peninsula, vadose hydrology; subterranean karst estuary

Online: 16 January 2018 (10:40:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints201711.0041.v1

Integrative Bioinformatic Analysis of Transcriptomic Data Identifies Conserved Molecular Pathways Underlying Ionizing Radiation-Induced Bystander Effects (RIBE)

Constantinos Yeles, Efstathios-Iason Vlachavas, Olga Papadodima, Eleftherios Pilalis, Constantinos E. Vorgias, Alexandros G. Georgakilas, Aristotelis Chatziioannou

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Bioinformatics; Ionizing radiation; Microarrays; Radiation-induced bystander effects; Transcriptomics

Online: 6 November 2017 (15:02:00 CET)

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Preprint ARTICLE | doi:10.20944/preprints201702.0032.v1

Estimating Recreational Value of Foy's Lake: An Application of Travel Cost Count Data Model for Truncated Zeros

Md. Touhidul Alam, Anis-Ul-Ekram Chowdury, Md. Sajib Hossian

Subject: Business, Economics And Management, Economics Keywords: individual travel cost method; zero truncated poisson regression model; endogenous stratification; consumer surplus

Online: 10 February 2017 (11:10:04 CET)

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Preprint ARTICLE | doi:10.20944/preprints202406.1791.v1

A Fast Multi-Threshold Color Image Segmentation Algorithm Using Bayesian Forecasting Evolutionary Algorithm

Yunzhi Jiang, Wei-chang Yeh, Zhengchun Lin

Subject: Computer Science And Mathematics, Computer Vision And Graphics Keywords: Bayesian Forecasting Evolutionary Algorithm (BFEA); Multilevel Thresholding Technique; Color Image Segmentation; Prediction Vector ;

Online: 26 June 2024 (06:34:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0190.v1

Na and K Intake from Lunches Served in a Japanese Company Cafeteria and the Estimated Improvement in the Dietary Na/K Ratio Using Low-Na/K Seasonings and Dairy to Prevent Hypertension

Nagako Okuda, Aya Higashiyama, Kozo Tanno, Yuki Yonekura, Makoto Miura, Hiroshi Kuno, Toru Nakajima, Tomomi Nagahata, Hirokazu Taniguchi, Koki Kosami, Kyoko Kojima, Akira Okayama

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: hypertension; nutrition; sodium; potassium; Japanese; company cafeteria; seasoning; dairy

Online: 2 April 2024 (10:37:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201608.0111.v1

Biological Activities of the Essential Oil from Erigeron floribundus

Riccardo Petrelli, Giuseppe Orsomando, Leonardo Sorci, Filippo Maggi, Farahnaz Ranjbarian, Prosper C. Biapa Nya, Dezemona Petrelli, Luca A. Vitali, Giulio Lupidi, Luana Quassinti, Massimo Bramucci, Anders Hofer, Loredana Cappel

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Erigeron floribundus; essential oil; antimicrobial; NadD; Trypanosoma brucei; cytotoxicity; antioxidant; limonene; caryophyllene oxide

Online: 10 August 2016 (12:36:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1412.v1

Comparison of New Inflammatory Marker Scoring Systems and Conventional Inflammatory Markers in Patients Over 65 Years of Age Admitted to the Intensive Care Unit: A Multicenter Retrospective Cohort Study

Özlem Çakin, Arzu Karaveli, Melike Yüce Aktepe, Ayça Gümüş, Özlem Esra Yildirim

Subject: Medicine And Pharmacology, Internal Medicine Keywords: intensive care unit; inflammatory markers; scoring systems; geriatric patient

Online: 22 May 2024 (15:29:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202008.0307.v1

Bringing onco-innovation to Europe’s healthcare systems: the unexploited potential of biomarker testing, real world evidence and the potential of Tumour Agnostics. The lesson from BRCA1/2 genetic testing

Denis Horgan, Gennaro CILIBERTO, Pierfranco Conte, Giuseppe CURIGLIANO, Luis Seijo, Luis M. Montuenga, Luis Paz-Ares, Marina Chiara Garassino, Penault-Llorca Frederique, Fabrizia GALLI, Isabelle Ray-Coquard, Denis Querleu, David R. Baldwin, Susana Banerjee, Peter H.J. Riegman, Keith Kerr, Benjamin Horbach, Reinhard Büttner, Hendrik Van Poppel, Anders Bjartell, Giovanni Codacci-Pisanelli, Westphalen Christoph Benedikt, Fabien CALVO, Jasmina Koeva-Balabanova, Stephen Hall, Angelo Virgilio Paradiso, Dipak. Kalra, Christa M. Cobbaert, Rocio Varea Mendez, Zorana Maravic, Vassiliki Fotaki, Jaafar Bennouna, Estelle Cauchin, Núria Malats, Iñaki Gutiérrez-Ibarluzea, Benjamin Gannon, Ken Mastris, Chiara Benini, William M. Gallagher, Simonetta Buglioni, Alastair Kent, Elisabetta Munzone, Ivica Belina, Jan P. van Meerbeeck, Michael Joe Duffy, Elzbieta. Sarnowska, Beata Jagielska, Sarah Mee, Ettore Domenico Capoluongo

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: cancer biomarkers, BRCA1/2, genomics; European recommendation

Online: 14 August 2020 (04:27:45 CEST)

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Preprint BRIEF REPORT | doi:10.20944/preprints202407.1621.v1

Oral Supplementation of L-Carnosine Attenuates Acute Stress-Induced Corticosterone Release and Mitigates Anxiety in CD157 Knockout Mice

Takahiro Tsuji, Kazumi Furuhara, Erchu Guo, YiJing Wu, Jing Zhong, Haruhiro Higashida, Yasuhiko Yamamoto, Chiharu Tsuji

Subject: Biology And Life Sciences, Other Keywords: L-carnosine; CD157; autism spectrum disorder; corticosterone; anxiety; stress

Online: 19 July 2024 (15:15:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1831.v1

High Sensitivity Detection of Oral Leukoplakia Comprehensive Analysis of P90 Biomarker Expression in Human Saliva and Tissue Samples

Hsiao-Hsuan Wan, Haochen Zhu, Chao-Ching Chiang, Jian-Sian Li, Fan Ren, Cheng-Tse Tsai, Yu-Te Liao, Dan Neal, Joseph Katz, Josephine F. Esquivel-Upshaw

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: oral cancer detection; oral leukoplakia; P90; high sensitivity; salivary biomarkers; MOSFET; tissue

Online: 28 April 2024 (08:08:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0178.v1

Eco-Friendly Microencapsulation of Lacticaseibacillus Paracasei Using Cissampelos pareira Leaf Extract as Natural Encapsulating Materials

Sasi Vimon, Chonticha Romyasamit, Rawiwan Chanpakdee, Sumaree Boonplu, Chackrit Nuengjamnong, Fonthip Makkliang, Suthinee Sangkanu, Veeranoot Nissapatorn, Phirabhat Saengsawang, Tina S. Dalgaard, Watcharapong Mitsuwan

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Cissampelos pareira; Lacticaseibacillus paracasei; microencapsulation; natural encapsulating material; probiotic supplementation

Online: 4 March 2024 (15:33:44 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0542.v1

A Simplified Screening Model to Predict the Risk of Gestational Diabetes Mellitus in Caucasian and Latin American Pregnant Women

María Arnoriaga-Rodríguez, Irene Serrano, Mateo Paz-Cabezas, Ana Barabash, Johanna Valerio, Laura Del Valle, Rocio Martin O´Connor, Verónica Melero, María Paz De Miguel Novoa, Angel Díiaz, Cristina Familiar, Inmaculada Moraga, Mario Pazos, Mercedes Martinez-Novillo, Miguel Ángel Rubio Herrera, Clara Marcuello, Ana M. Ramos-Leví, Pilar Matía-Martín, Alfonso Calle-Pascual

Subject: Medicine And Pharmacology, Endocrinology And Metabolism Keywords: Gestational Diabetes Mellitus; Caucasian; Latin American; age; body mass index; fasting plasma glucose; single-nucleotide polymorphisms.; women

Online: 11 March 2024 (09:29:04 CET)

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Preprint ARTICLE | doi:10.20944/preprints202404.1091.v1

River Habitat Survey (RHS) method in the assessment of synecological characteristics of macroinvertebrates: Aquatic Heteroptera of the River Krąpiel valley

Grzegorz Michoński, Andrzej Zawal, Grzegorz Tończyk, Wojciech Płaska, Joanna Pakulnicka, Vladimir Pešić, Michał Grabowski, Aleksandra Bańkowska, Agnieszka Szlauer-Łukaszewska, Robert Stryjecki, Magdalena Achrem, Iga Lewin, Zuzanna Krzynówek, Maja Krakowiak, Stanisław Musielak, Tapas Chatterjee, Edyta Stępień-Zawal

Subject: Biology And Life Sciences, Aquatic Science Keywords: hydromorphology; hydromorphological indexes; water bugs; landscape scales, physico--chemical parameters

Online: 17 April 2024 (07:51:31 CEST)

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Preprint REVIEW | doi:10.20944/preprints202408.0662.v1

New Insights into Chronic Pancreatitis Treatment: Potential Mechanisms and Applications of Probiotics and Prebiotics

Yingyu Pan, Jianing Li, Zhengyang Fan, Yonghao Chen, Xiaoxuan Huang, Dong Wu

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: chronic pancreatitis; probiotics; prebiotics; gut microbiota

Online: 12 August 2024 (03:05:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1609.v1

Study on Body Weight-Length Relationship and Relative Fatness of Bigeye Grunt Brachydeuterus auritus in the Coastal Waters off Sierra Leone

Guoqing Zhao, Xin Rao, Shuai Li, Jialiang Yang, Lingzhi Li, Hongliang Huang

Subject: Biology And Life Sciences, Aquatic Science Keywords: bigeye grunt; body-length weight relationship; relative fatness; environment factor; Sierra Leone

Online: 24 April 2024 (11:49:14 CEST)

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Bigeye grunt Brachydeuterus auritus is an important economic species in the waters off Sierra Leone in West Africa, with great ecological value. Based on the survey data of bottom trawl nets from 6 voyages from 2019 to 2021, the body weight-length relationship (WLR), as well as their relative fatness, were studied in depth using the method of body length and its corresponding mean body weight. This study fitted the WLR of bigeye grunt by gender, calculated its fullness, and analyzed the influence of environmental factors. The results showed that month and gender had a significant impact on body length and weight distribution (P<0.01). There was a highly significant negative correlation (P<0.01) between the condition factor (a) and the allometric factor (b) in the WLR, and salinity significantly affects b (P<0.05). The (lga)/b ratio was less affected by environmental factors which may be related to the body size and density of the fish. The difference in b between male and female populations was extremely significant (P<0.01). The relative fatness had significant seasonal variation characteristics, with highly significant effects of sex and body length (P<0.01). With increasing body length, the relative fatness showed two types of changes, continuously increasing and first increasing then decreasing, with salinity and b significantly affecting the type of change (P<0.05) and depth having a highly significant effect (P<0.01). The bigeye grunt off the coast Sierra Leone exhibited significant seasonal growth characteristics, with significant differences in growth characteristics between male and female individuals. This study suggested that salinity may be the main factor affecting its growth and development. In addition, this study hypothesised that the peak breeding season may occur during the dry season, beginning in December and ending before April of the following year. The study provides updated and more comprehensive insights into the biology and ecology of the bigeye grunt offshore Sierra Leone, West Africa, which can provide scientific basis for its resource assessment, development and utilization, and resource management.

Preprint ARTICLE | doi:10.20944/preprints202403.0822.v1

Coxsackievirus A7 and Enterovirus A71 Significally Reduce SARS-CoV-2 Infection in Cell and Animal Models

Victor A. Svyatchenko, Stanislav S. Legostaev, Roman Y Lutkovskiy, Elena V. Protopopova, Eugenia P. Ponomareva, Vladimir V. Omigov, Oleg S. Taranov, Vladimir A. Ternovoi, Alexander P. Agafonov, Valery B. Loktev

Subject: Biology And Life Sciences, Virology Keywords: SARS-CoV-2; coxsackievirus A7; enterovirus A71; co-infection; Syrian hamster

Online: 14 March 2024 (09:33:51 CET)

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Preprint ARTICLE | doi:10.20944/preprints201612.0038.v1

Chemical Fingerprint Analysis and Quantitative Analysis of Rosa Rugosa by UPLC-DAD

Sanawar Mansur, Rahima Abdullab, Amatjan Ayubicb, Haji Akbar Aisa

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: Rosa rugosa; UPLC-DAD; quality control; fingerprint

Online: 7 December 2016 (11:11:00 CET)

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Preprint ARTICLE | doi:10.20944/preprints202409.1847.v1

Exploring the Potential of Salicylic Acid and Arbuscular Mycorrhizae in Boosting the Growth and Flowering Response of Statice (Limonium sinuatum [L.] Mill.)

Shriya Gupta, Nomita Laishram, Arvinder Singh, Ritika Manhas, Kedar Mahadev Gheware, Gurdev Chand, Rajesh Kumar Pandey

Subject: Biology And Life Sciences, Horticulture Keywords: Statice; salicylic acid; arbuscular mycorrhiza; growth; flowering

Online: 24 September 2024 (11:57:08 CEST)

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In sustainable floriculture, the integration of arbuscular mycorrhizal fungi (AMF) and salicylic acid (SA) in the cultivation of statice flowers presents a promising ecofriendly approach to enhancing crop health and productivity. AMF improve nutrient uptake, particularly phosphorus, in plants, leading to stronger growth and abundant flowering while reducing the reliance on chemical fertilizers. Additionally, AMF enhance soil structure and water retention, fostering robust root systems and increasing the plant's resilience to drought and soil-borne pathogens thus improving soil health and minimizing environmental impact. Complementarily, the application of salicylic acid boosts the plant’s innate defense mechanisms, elevating its resistance to diseases, enhancing stress tolerance, helping statice flowers withstand adverse conditions such as drought and salinity, and promotes vigorous root development for better nutrient absorption. Hence, this study evaluates the effect of mycorrhizal inoculation and salicylic acid treatment on ornamental statice (Limonium sinuatum [L.] Mill.) cv. Qis White. The investigation involves two primary factors: mycorrhizal inoculation and salicylic acid concentration. For mycorrhizal inoculation, the study compares the untreated control with treatments including Glomus mossae, Gigaspora margarita, and a mixture of both fungi (applied as basal during transplanting). For salicylic acid, the study assesses the untreated control alongside treatments with Salicylic Acid at 100 mg L-1, 150 mg L-1, and 200 mg L-1 (applied as foliar spray at 45 and 90 days after transplanting) in a factorial RCBD experiment with three replications. Growth, flowering, yield and biomass parameters were assessed in this study. The results indicated that statice plants benefited from mycorrhizal inoculation, particularly with Glomus mosseae, when paired with salicylic acid @ 200 mg L-1. This was further validated by principal component analysis. AMF inoculated plants showed improved growth, and superior flower qualities compared to non-inoculated plants. Additionally, the application of salicylic acid demonstrated positive effects across various parameters. Notably mycorrhization led to a delay of 4 to 9 days in the flowering time of statice. In conclusion, mycorrhizal inoculation and salicylic acid can enhance the growth and flowering attributes of statice by choosing the appropriate mycorrhizal inoculum and optimal salicylic acid concentrations. In the future they can contribute to more sustainable and productive statice cultivation by reducing the need for chemical inputs and supporting overall plant health.

Preprint ARTICLE | doi:10.20944/preprints202409.1723.v1

Effectiveness of Three Front-of-Pack Food Labels in Guiding Consumer Identification of Nutrients of Concern and Purchase Intentions in Kenya: A Randomized Controlled Trial

Shukri F Mohamed, Caroline H Karugu, Samuel Iddi, Veronica Ojiambo, Caliph Kirui, Gershim Asiki

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: front-of-pack-labels (FOPL); warning labels (WL); packaged foods; salt; sugar; saturated fats; fat; randomized controlled trial (RCT); Kenya ;

Online: 23 September 2024 (12:00:17 CEST)

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Background: Front-of-pack-labels (FOPLs) on packaged foods provide consumers with essential information about the nutritional content of food products, enabling them to make informed choices and align their dietary habits with their health goals. However, evidence on the comprehensibility, use, and effectiveness of FOPLs remains limited, particularly in low- and middle-income countries like Kenya. Objective: In this study, we assessed the effectiveness of three FOPLs in helping consumers identify excess nutrients of concern in packaged food products and their potential influence on food purchases in Kenya. Methods: A total of 2198 shoppers with diverse backgrounds were recruited from selected supermarkets in three Kenyan main cities (Nairobi, Mombasa, Kisumu) and a small town (Garissa). Participants were randomized to three FOPLs: Red and green Octagon label (RG), Red and Green Octagon with icons (RGI) and a black Octagon Warning label (WL). In the control phase, participants were shown unlabeled images of packaged food products and they responded to a set of questions. In the experimental phase, the same product images were presented with one of the three front-of-pack labels they were randomized to, and participants answered the same questions again. Differences in the proportions of participants correctly identifying the nutrients of concern and the changes in intention to purchase unhealthy foods before and after exposure to FOPLs were analyzed using frequency tables and Chi-Square tests. The effectiveness of the three FOPLs was further assessed using a modified Poisson regression. Results: Results showed that exposure to FOPLs significantly improvement participants' ability to correctly identify nutrients of concern across various food categories. Additionally, FOPLs reduced consumers’ intentions to purchase unhealthy foods, with the Warning Labels (WL) emerging as particularly effective in enhancing consumers' understanding of product healthiness and reducing the intention to purchase unhealthy foods compared to the other two FOPLs. Conclusion: These findings underscore the potential role of FOPLs, particularly the WL as an effective regulatory tool for promoting healthier food choices in Kenya.

Preprint ARTICLE | doi:10.20944/preprints202408.1512.v1

Molecular Confirmation, Epidemiology, and Pathophysiology of Ehrlichia canis Prevalence in Eastern India

Ankita Chakraborty, Prasana Kumar Rath, Susen Kumar Panda, Bidyut Prava Mishra, Manaswini Dehuri, Sangram Biswal, Manoj Kumar Jena, Basanta Pravas Sahu, Biswaranjan Paital, Dipak Kumar Sahoo

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: Canine Ehrlichiosis; dog’ s pathophysiology; Ehrlichia epidemiology; molecular identification; p28 gene; ticks; ultrasonography

Online: 21 August 2024 (08:39:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1571.v1

How Distressed Are Adolescent Students? A Mix-Method Study on High School Students in Northern Italy, Two Years after the Beginning of the COVID-19 Pandemic

Anna Maria Della Vedova, Loredana Covolo, Carlotta Fiammenghi, Silvia Marconi, Umberto Gelatti, Maurizio Castellano, Barbara Zanini

Subject: Social Sciences, Psychology Keywords: study engagement; adolescents; school; youths; stress; eating behaviors; smartphone overuse

Online: 19 July 2024 (11:04:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0804.v1

Results of Tendon Transfers in Radial Nerve Palsies: A New Evaluation Protocol

Micaela Reina, Simonetta Odella, Mauro Magnani, Francesco Locatelli, Alice Clemente, Martina Macrì, Pierluigi Tos

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: periferal nerve injuries, radial palsy, tendon transfer, protocol in nerve palsy

Online: 12 June 2024 (09:31:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1891.v1

Prospective Study to Evaluate Rectus Femoris Muscle Ultrasound for Body Composition Analysis in Patients Undergoing Bariatric Surgery

Andreu Simó Servat, Montse Ibarra, Mireia Libran, Lilian Escobar, Verónica Perea, Carmen Quirós, Carlos Puig-Jové, María-José Barahona

Subject: Medicine And Pharmacology, Endocrinology And Metabolism Keywords: Musculoskeletal Ultrasound; Rectus femoris; Bariatric Surgery; Sarcopenic obesity

Online: 28 May 2024 (15:41:23 CEST)

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Background: Bariatric surgery (BS) has a significant impact on body composition (BC) and con-sequently may affect established sarcopenic obesity (SO) in candidate patients. The aim of this study is to assess the utility of muscle ultrasound (MUS) of rectus femoris thickness (RFT) for the evalua-tion of BC and skeletal muscle function in patients undergoing BS compared to bioimpedance analysis (BIA), dual-energy X-ray absorptiometry (DEXA) and dynamometry. On the other hand, we aim to demonstrate how MUS of RFT correlates better with the quality of life (Qol) in this population, likely because it enables the detection of regional quadriceps muscle sarcopenia, in comparison to the other mentioned methods. Methods: This is a prospective pilot study including 77 subjects (64.9% female, mean age: 53.2 ± 8.67 years) who underwent BS. Handgrip strength was measured using a dynamometer, fat-free mass index (iFFM) was assessed by BIA, appendicular muscle index (AMI) was calculated using DEXA and RFT was measured by MUS. Moreover, Homeostasis Model Assessment of Insulin Resintance (HOMA-IR) was calculated. All these measurements were conducted 1 month prior to BS and at the 12-month follow-up. QoL was as-sessed using the Moorehead-Ardelt questionnaire. Results: The mean BMI decreased by 12.95 ± 3.56 kg/m2 (p=0.001). Firstly, we observed positive correlation pre-surgery between HOMA and: RFT (r=0.27, p=0.02), iFFM (r=0.36, p=0.001), AMI (r=0.31, p=0.01) and dynamometer (r=0.26, p=0.02). In addition, we found correlation between RFT and iFFM (pre-surgical: r=0.31, p=0.01; post-surgical: r=0.25, p=0.05) and between RFT and lower extremities AMI post-surgical (r=0.27, p=0.04). Secondly, we observed significant reductions in iFFM, AMI and RFT (p=0.001), but not with dynamometer (p=0.94). Finally, a tendency to a positive correlation between QoL question-naire and RFT post-surgery (r=0.23, p=0.079) was observed. Conclusions: Our results suggest that RFT measured by MUS for the evaluation of SO and the follow-up after BS of these patients. Moreover, RFT can provide relevant information about regional sarcopenia and probably has an accurate correlation with QoL in comparison with the other methods.

Preprint ARTICLE | doi:10.20944/preprints202404.1415.v1

Crossing the ‘Resource Curse’: Exploring Sustainable Development Paths from the Divergence of Economic Growth in China's Resource-Based Cities

Jiahao Chen, Tongping Li, Jinhua Cheng, Cheng Zhan, Yanqiong Zhao, Chuandi Fang

Subject: Business, Economics And Management, Economics Keywords: Resource-based Cities; Resource Curse; Economic Growth Divergence; Sustainable Development

Online: 23 April 2024 (03:16:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0438.v1

Relationship of Body Condition Score, Body Parameters and Body Carcass Fat in Coopworth Breeding Ewes

Ahmad Shalaldeh, Shannon Page, Patricia Anthony, Stuart Charters, Majeed Safa, Chris Logan, Rebecca Johnson

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: body condition score; body parameters; body carcass fat; live weight; ewes condition; image analysis; Artificial neural network

Online: 5 April 2024 (12:13:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0005.v1

Early Weigth-Bearing Using Narrow Symmetrical Distal Fibular Plate

Domenico Tigani, Corrado Maria Leonida, Giuseppe Mobilia, Cesare Donadono, Alessandro Ortolani, Giuseppe Melucci, Stefano Stallone

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: closed ankle fractures; distal fibular fractures; early weight-bearing

Online: 1 March 2024 (07:43:30 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.1138.v1

Assessing the Performance of a Hand-held Laser Scanning for Individual Tree Mapping in an Urban Area

Jinming Yang, Wenwen Yuan, Huicui Lu, Yuehan Liu, Yongkang Wang, Letong Sun, Shimei Li, Haifang Li

Subject: Biology And Life Sciences, Forestry Keywords: LiDAR; mobile laser scanning; personal laser scanning; forest inventory; point cloud

Online: 20 February 2024 (10:46:47 CET)

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Preprint ARTICLE | doi:10.20944/preprints201701.0033.v1

Establish and Apply a Safe and Convenient Pseudovirus-Based Assay to Detect Neutralizing Antibodies against Influenza A (H7N9) Virus

Li Zhang, Jing Lu, Jingxing Li, Rong Tang, Haiyan Peng, Fanyue Meng, Yuemei Hu

Subject: Biology And Life Sciences, Virology Keywords: H7N9 avian influenza; pseudovirus; neutralization assay; relative luminescence units (RLU)

Online: 6 January 2017 (10:21:52 CET)

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Preprint ARTICLE | doi:10.20944/preprints202410.1098.v1

A Hybrid Improved Particle Swarm Optimization and Genetic Algorithm for Energy Efficient Task Offloading in Industrial IoT Edge Computing Network

Vijayaram Boopalan, Vasudevan V

Subject: Computer Science And Mathematics, Computational Mathematics Keywords: industrial internet of things, improved particle swarm optimization with genetic algorithm, edge computing, optimization, task offloading, IoT, signal processing

Online: 15 October 2024 (07:27:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202410.0759.v1

Urban Resilience Amid Supply Chain Disruptions: A Causal and Cointegration-Based Risk Model for G-7 Cities Post-COVID-19

Haibo Wang, Lutfu S.Sua

Subject: Business, Economics And Management, Business And Management Keywords: supply chain risk; VAR; FAVAR; causality analysis

Online: 10 October 2024 (09:09:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0056.v1

Evidence of the Detrimental Effects of Bacterial Resistance to Cephalosporins and Penicillins in Egypt’s Primary Healthcare Facilities

Mohammed Mahmoud Shawky Kassab

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Antibiotic; Resistance; Infection, bacteria; Nanopore sequencing technique

Online: 3 September 2024 (05:22:55 CEST)

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Background: Bacterial resistance to several antibiotic classes is seen as a grave threat worldwide. Bacterial resistance to antibiotics was mostly caused by the abuse and overuse of antibiotics, particularly penicillins and first-generation cephalosporins, in Egypt's primary healthcare facilities. Aim of the study: To investigate the main resistant bacteria to a few chosen penicillins and first-generation cephalosporins, as well as the characterization of these antibiotics' resistant genes and their detrimental effects in Egypt's main medical facilities. Methodology: Two hundred respiratory and urinary tract infection (RTI and UTI) specimens were gathered from Egyptian primary medical center patients. The turbidimetric assay at 630 nm wavelength, the broth dilution technique, and the nanopore sequencing homology approach were used to characterize the major resistant pathogenic bacteria and their resistant genes to cefadroxil (first generation cephalosporins) and nafcillin (antipseudomonal penicillin). Moreover, adverse outcomes resulting from antibiotic resistance were noted. Results: Out of 200 specimens with RTI and UTI, 186 samples showed the proliferation of resistant bacteria isolates. Enterococcus faecium strain NFC and Staphylococcus aureus strain CDX were among them. Nanopore sequencing confirmed that the antibiotic-resistant gene in Enterococcus faecium was the NFC gene, whereas the antibiotic-resistant gene in Staphylococcus aureus was the CDX gene. Penicillin-binding proteins with modest affinity were encoded by both genes. These bacterial resistance patterns were linked to a low death rate of 5% and a high morbidity rate of 47%. Conclusion: By expressing low-affinity penicillin-binding proteins through resistant NFC and CDX genes, Enterococcus faecium strain NFC and Staphylococcus aureus strain CDX were found to be the predominant bacterial isolates that cause antibiotic resistance to first-generation cephalosporins and penicillins.

Preprint CONCEPT PAPER | doi:10.20944/preprints202408.1154.v1

Born Digibal - The Internationalization of Enterprises in the Context of the Digital Transformation of the Global Economy

Zuzanna Maleszewska, Marceli Hazla

Subject: Business, Economics And Management, Economics Keywords: digitalization; internationalization; globalization; born digital; born global; born digibal

Online: 15 August 2024 (14:44:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1904.v1

Double Polarized Optical Link for Mobile Networks

Tibor Berceli, Nada Badraoui

Subject: Engineering, Telecommunications Keywords: double orthogonal polarization; capacity enhancement; combined optical – wireless link; polarization extinction ratio

Online: 27 June 2024 (02:46:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1871.v1

Recognition of Derived Semantic Relationships in Geographic Entity Generic Names

Liu Hanyou, Mao Xi

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: recognition of general name derivation relationships; identification of general name derived geographical name; geographical name semantic features; geographic entity spatiotemporal distribution features; semantic spatiotemporal feature fusion

Online: 26 June 2024 (12:19:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1422.v1

Sustainability: Is It a Strategic Management Research Fashion?

Edgars Sedovs, Tatjana Volkova

Subject: Business, Economics And Management, Business And Management Keywords: strategic management; sustainability; corporate social responsibility; bibliometric analysis; management research fashion.

Online: 21 June 2024 (05:28:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0097.v1

Exhibition of Corallopyronin A an Antibiotic from Different Soil Environments in Egypt

Mohammed Mahmoud Shawky Kassab

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Corallopyronin A; Infection; Antibiotic; Resistance; Myxobacteria

Online: 2 May 2024 (12:14:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0975.v1

Production of Myxopyronin a Antibiotic from Different Soil Environments in Egypt

Mohammed Mahmoud Shawky Kassab

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Myxopyronin A; Infection; Antibiotic; Resistance; Myxobacteria

Online: 15 April 2024 (13:51:27 CEST)

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Background: Antibiotic resistance is an overwhelming serious difficulty globally. This necessitates the exploration of novel sources of antibiotics to overcome this challenge. Aim of the study: Bacterial Myxopyronin A production from various soil environments Egypt; as well as testing its antimicrobial activity in preclinical animal testing and randomized human clinical trials phases 1/2. Type of the study: Screening experimental study. Methodology: Different soil environments in Egypt were screened for the growth of bacterial isolates producing Myxopyronin A as an antimicrobial agent. Purification of Myxopyronin A was performed via reversed-phase HPLC. Paper disc diffusion assay, as well as the Broth dilution technique, were exploited to assess the invitro antimicrobial and minimum inhibitory concentration( MIC) of the test antibiotic. Furthermore, in vivo antimicrobial spectrum, adverse drug reactions, and pharmacokinetics were detected during animal model testing stages and human randomized clinical trials phases 1/2. Results: From the culture supernatant of the Myxobacterium Myxococcus fulvus 124B02 which was the predominant soil bacterial isolate grown on the Casein yeast peptone plate, Myxopyronin A was produced. The test antibiotic blocked the growth of many Gram +ve bacteria with MICs less than 100 mcg/ ml. In contrast, it inhibited the growth of a few Gram -ve bacteria such as Escherichia coli at MICs greater than 100 mcg/ ml. On the other hand, Eukaryotic cells such as fungal and human cells were not affected. Prokaryotic DNA-dependant-RNA polymerase( RNLP) was noticed to be inhibited via the test antibiotic suggesting its bactericidal action. The maximum concentration was 7-8 mcg/ ml at a maximum time of 2 hours when 600 mg dose was orally administered in randomized human clinical trials phases 1/2, and T1/2 reached 2.5 hours following first-order kinetics of elimination. The duration of its action was nearly 12 hours after oral administration. Rare toxicity was detected during preclinical and randomized human clinical trials phases 1/2 in the form of mild diarrhea and cholestatic jaundice in less than 5 % of experimental candidates. Conclusion: The present study was promising due to the bactericidal antibiotic Myxopyronin A production from Myxococcus fulvus 124B02 isolated from different soil environments in Egypt.

Preprint ARTICLE | doi:10.20944/preprints202403.1558.v1

Local DER Control with Reduced Loop Interactions in Active Distribution Networks

Giuseppe Fusco, Mario Russo

Subject: Engineering, Electrical And Electronic Engineering Keywords: decentralized voltage control; MIMO models; IMC technique; loops interaction; active power support to voltage regulation; robustness; simulations

Online: 26 March 2024 (13:07:24 CET)

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Preprint ARTICLE | doi:10.20944/preprints201608.0026.v1

Propose of Mix Design Method for CO₂ Reduction Concrete Using the Regression Analysis

Tae Hyoung Kim

Subject: Engineering, Civil Engineering Keywords: concrete; sustainability; regression analysis mix design; CO2 emission; cost

Online: 3 August 2016 (06:05:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1070.v1

Joint Action of Trichoderma atroviride and a Vegetal Derived-Protein Hydrolysate Improves Yield, Fruit Quality and Economic Profitability of Two Woodland Strawberry Cultivars Grown Under Greenhouse

Lorena Vultaggio, Enrica Allevato, Beppe Benedetto Consentino, Pietro Bellitto, Simona Napoli, Claudio Cannata, Georgia Ntatsi, Sonya Vasto, Sara Baldassano, Salvatore La Bella, Claudio Leto, Leo Sabatino

Subject: Biology And Life Sciences, Plant Sciences Keywords: Fragaria vesca L.; microbial biostimulant; non-microbial biostimulant; biostimulant 2.0; neglected species

Online: 19 March 2024 (10:20:22 CET)

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Woodland strawberry (Fragaria vesca L.) is an underutilized plant species, appreciated by consumers for its qualitative features. Utilizing technical means of production, such as plant biostimulants, that can increase crop productivity and quality could be highly important in woodland strawberry cultivation. The scope of the present study was to appraise the influence of two biostimulants (Trichoderma atroviride and plant protein hydrolysate) - used either alone or combined - on plant performance and economic profitability of two woodland strawberry genotypes (‘Alpine’ and ‘Regina delle Valli’). Overall, data showed that ‘Alpine’ had the highest productive performances, whereas ‘Regina delle Valli’ revealed the highest fruit qualitative traits. T. atroviride inoculation and V-PH application significantly boosted plant marketable yield (+20.5% for T. atroviride and +12.9% for V-PH), total sugars (+1.9% for Trichoderma and +1.4% for V-PH) and anthocyanins (+14.1% for T. atroviride and +9.8% for V-PH) compared to non-treated plants. Plants supplied with both biostimulants had higher marketable yield (+34.8%), mean fruit weight (+6.0%), fruit dry matter (+13.8%), total sugars (+3.5%), ascorbic acid (+12.7%), flavonoid (+26.3%) and anthocyanins (+29.9%) compared to non-treated plants. Furthermore, our study revealed that the highest fruit polyphenols concentration was recorded in both genotypes treated with the combination of biostimulants and in ‘Regina delle Valli’ sprayed with V-PH, whereas the highest antioxidant activity was found in ‘Regina delle Valli’ fruit when plants were supplied with both biostimulants. Our study pointed out that the application of microbial and non-microbial biostimulants, especially in combination, might be an useful strategy for improving performances of underutilized species and, therefore, encourage its cultivation, valorisation and economic profitability (+10195.3 €/ha when plants were exposed to both biostimulants).

Preprint ARTICLE | doi:10.20944/preprints202403.0518.v1

Avogadro Number’s-oriented HyperGeometric and ChebyshevT Functions for Black Hole Paradox Generalizations and Turing Machine Ruled Quantum Homeopathy Water Memory Entanglements for the Translation of COVID19 Homeopathy Remedies into the Neprilysin and ACE2/AT1R receptors targeted DRVYIHPFX- ligands.

Ioannis George Grigoriadis

Subject: Computer Science And Mathematics, Discrete Mathematics And Combinatorics Keywords: COVID19; ; Chern-Simons Topological; QED (Quantum Electrodynamics); Homeopathic medicine; Water Memory; AI-Quantum computing; Quantum-Inspired Evolutionary Algorithm Predictive Toxicology; QSAR Quantum gates; CS Supergravity Quantum Foam; Cheminformatics artificial intelligence; Phase Data Mining; Machine Learning; Euclid Chemical space exploration; (bosonic) Quantum fields Theory (QFT); Angiotensin Receptor Neprilysin targeted DRVYIHPFX mimetic Holomorphic Ligands; Hidden Entanglement Negativity Translations; Uncertainty Quantum Relationships; Quantum fields theory; Quantum information; HyperGeometric Functions; Chemical Block Systems; Black Hole Paradox Generalizations; SphericalHarmonicY-Supersymmetry breaking foundations; WhittakerM Functions; Hypergeometric1F1 Functions; Turing Machine Learning Ruled Calculations; Avogadro Number’ s oriented Quantum Homeopathy Hidden Entanglement Negativities; Quantum foam; non-commutative geometry; small molecule ligand engineering; prot

Online: 11 March 2024 (03:52:07 CET)

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Preprint ARTICLE | doi:10.20944/preprints202410.0716.v1

Partial Reprogramming Exerts a Rejuvenating Effect on Human Mesenchymal Stem Cells Underwent Replicative Senescence in Culture

Julia Ivanova, Mariia Shorokhova, Natalia Pugovkina, Irina Kozhukharova, Larisa Alekseenko, Nikita Guriev, Ivan Kuneev, Alisa Domnina, Tatiana Grinchuk, Victoria Zemelko, Olga Lyublinskaya

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: partial reprogramming; mesenchymal stem cells; replicative senescence; rejuvenation; Sendai virus; Yamanaka factors

Online: 9 October 2024 (15:31:48 CEST)

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Preprint BRIEF REPORT | doi:10.20944/preprints202408.1591.v1

Comparison of Chest Ct Findings and Pulmonary Function Tests in Non-symptomatic Children with Rheumatic Diseases

Spyridon Prountzos, Kyveli Chiotopoulou, Katerina Kourtesi, Evdoxia Sapountzi, Dafni Moriki, Elpiniki Kartsiouni, Efthymia Alexopoulou, Konstantinos Douros, Lampros Fotis

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: Lung; Pediatrics; Rheumatic Diseases; Spirometry; Tomography, X-ray Computed

Online: 21 August 2024 (16:00:51 CEST)

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Preprint REVIEW | doi:10.20944/preprints202408.1370.v1

Mycologists and Virologists Align: Proposing Botrytis cinerea for Global Mycovirus Study

Mahmoud E. Khalifa, María A Ayllón, Lorena Rodriguez-Coy, Kim M Plummer, Anthony R Gendall, Kar Mun Chooi, Jan A.L. van Kan, Robin M MacDiarmid

Subject: Biology And Life Sciences, Virology Keywords: model system; Botrytis cinerea; mycovirus

Online: 21 August 2024 (02:28:54 CEST)

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Preprint REVIEW | doi:10.20944/preprints202407.1393.v1

Tubal Cancer Clinical Management: Two Exceptional Scenarios and a Review of the Literature

Irene Colombi, Marco D’Indinosante, Lucia Lazzeri, Errico Zupi, Silvia Pisaneschi, Marco Giusti, Alberto Mattei, Elisa Valentina Debonis, Angelo Cassisa, Anna Franca Cavaliere, Federica Perelli

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: tubal cancer; ovarian cancer; tubal carcinoma; primary debulking surgery; serous tubal intraepithelial carcinoma; STIC; high-grade serous carcinoma

Online: 17 July 2024 (13:55:21 CEST)

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Preprint REVIEW | doi:10.20944/preprints202404.1377.v1

A Comprehensive Review on Alcohol Abuse Disorders Fatality, from Alcohol Binge to Alcoholic Cardiomyopathy

Antonina Argo, Maria Puntarello, Walter Pitingaro, Roberto Buscemi, Tommaso D'Anna, Ginevra Malta, Giuseppe Davide Albano, Stefania Zerbo

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: alcohol intake; cardiomyopathy; sudden death; arrhythmias; stroke; hypertension; gender; Takotsubo; forensic

Online: 22 April 2024 (10:28:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1220.v1

Volatile Characterization of Recovery Minority Varieties from Castilla-La Mancha Region (Spain)

Cristina Cebrián-Tarancón, A.Sergio Serrano, Juan L. Chacón-Vozmediano, Jesús Martínez-Gascueña, Gonzalo L. Alonso

Subject: Biology And Life Sciences, Plant Sciences Keywords: recovered grapevine cultivars; aroma compounds; aroma potential; water stress

Online: 18 April 2024 (11:04:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0420.v1

Pirfenidone Reverts Global DNA Hypomethylation, Promoting DNMT1/UHRF/PCNA Coupling Complex in Experimental Hepatocarcinoma

Hipolito Otoniel Miranda-Roblero, Liliana Faridi Saavedra-Salazar, Marina Galicia-Moreno, Scarlet Arceo-Orozco, Fernando Caloca-Camarena, Ana Sandoval-Rodríguez, Jesús García-Bañuelos, Claudia Frias-Gonzalez, Monica Almeida-López, Erika Martínez-López, Juan Armendariz-Borunda, Hugo Christian Monroy-Ramirez

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Hepatocellular carcinoma; DNMT1; DNMT3a; c-Myc; β -catenin

Online: 5 April 2024 (08:39:31 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202410.0744.v1

Mangrove Ecosystem Transformation Approach (META) Innovation Design as Strengthening Business Resilience and Environmental Sustainability of in East Java

Darwin Yuwono Riyanto, Rudi Santoso, Januar Wibowo

Subject: Business, Economics And Management, Business And Management Keywords: Mangrove Ecosystem; Business Resilience; Environmental Sustainability; Tourism Innovation; East Java

Online: 10 October 2024 (09:03:58 CEST)

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Preprint REVIEW | doi:10.20944/preprints202408.2266.v1

Technological Interventions to Implement Prevention and Health Promotion in Cardiovascular Patients

Ayisha Zaka Bashir, Anji Yetman, Melissa Wehrmann

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Health promotion; cardiology; technology; cardiac rehabilitation; telemedicine and telehealth

Online: 30 August 2024 (15:36:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1551.v1

The Impact of Delayed Retirement and Adjustments to Birth Policies on the Macroeconomy

Qingsheng Zhu, Jitao Du, Yanhong zuo

Subject: Social Sciences, Government Keywords: Population aging; Birth policies; Delayed retirement; Economic growth

Online: 21 August 2024 (11:45:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1339.v1

Study on Minimum Inhibitory Concentration of Selected Antibacterials against Bacterial Isolates from Canine Pyometra

Avinash Chhetri, Madhav Paudel, Tulsi Ram Gompo, Sharada Thapaliya

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: Minimum Inhibitory Concentration (MIC); Canine Pyometra; Antibiotic Sensitivity; Potency; Susceptibility; Bacterial Isolates; Agar Dilution Method; Antimicrobial Resistance (AMR)

Online: 19 August 2024 (12:12:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0872.v1

Pregnancy Outcomes Following Participation in the Healthy Women Healthy Futures Doula Program in New York City

Diana Romero, Meredith Manze, Mukta Mohnani

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: doulas; pregnancy outcome; health disparities; maternal health; women of color

Online: 13 August 2024 (17:06:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0721.v1

An Experimental Insight on The Use Of N-Butanol as Sustainable Aviation Fuel

Grigore Cican, Radu Mirea

Subject: Engineering, Energy And Fuel Technology Keywords: butanol; kerosene; ; aviation; turbo engine; fuel; sustainability

Online: 10 August 2024 (17:10:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0353.v1

Resilient Farm Technologies in Achieving Sustainable Development: Performance and Adoption of Sri under Multiple Constraints in Odisha, India

Debdutt Behura, Surajit Haldar, Pandaba Charana Munda, Ashutosh Pal

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: SRI; Dis-adoption; Sustainability; resource conservation; probit; odisha

Online: 6 August 2024 (05:54:22 CEST)

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Rice yield underperformance coupled with production instability in Odisha state of India is primarily due to low irrigation potential, the spatiotemporal disparity in rainfall pattern and relentless confrontation with biotic and abiotic stresses. System of Rice Intensification (SRI) was introduced in the state with the promises of higher production horizon. However, the present scenario of patchy adoption pattern has necessitated comprehensive study on dynamics and determinants of adoption of SRI. We found that, 57 percent farmers continued SRI, 28 percent discontinued and rest were practicing conventional rice farming. The focused group discussion among the farmers helped us to triangulate the determinants of SRI adoption.The increased SRI area allocation was observed at the expense of reduced number of adopting farmers. Economic scarcity of skilled labour, difficulties in transplantation and mechanical weeding, low irrigation potential and poor on-farm water management were major constraints in SRI practice. Farmers’ compliance in following different resilient SRI components that also varied spatiotemporally has resulted in realized incremental yield. SRI was proved to be resilient to severe drought during 2015-16 and yielded 27 percentage higher than conventional one with considerable decline in hazardous chemicals usage. Farmers’ decision on SRI adoption/discontinuation was analysed using probit regression analysis. The results indicated that, active social involvements of NGOs, on-farm training and demonstrations, and realized incremental rice income influenced SRI adoption. On the other hand, SRI area expansion hindered mainly because of infeasible land topography, area saturation and lack of farmers’ interest. The sustainability index was developed to analyse SRI’s performance to other conventional methods at farm level. Comparatively, SRI adopters benefitted in terms of incremental net return by enhancing ecological balance and sustained productivity of soil, use of eco-friendly and own farm inputs. Nonetheless, higher women labour displacement observed under SRI can be curtailed by providing training to young farm women.

Preprint ARTICLE | doi:10.20944/preprints202407.2536.v1

Interplay between mTORC1 and mTORC2 in Regulating cAMP Signaling and Cell Adhesion in Dictyostelium discoideum

Pundrik Jaiswal

Subject: Biology And Life Sciences, Life Sciences Keywords: ; dictyostelium; cell adhesion; caffeine; mTORC1; mTORC2 ;

Online: 31 July 2024 (09:55:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.2046.v1

Crack Identification Method for Prefabricated Concrete Pavement Based on Distributed Strain Monitoring

Yongsheng Tang, Bohan Zheng, Tao Yu

Subject: Engineering, Civil Engineering Keywords: Prefabricated concrete pavement; Distributed long-gauge optic fiber sensing; Crack identification; Strain curve envelope area ratio

Online: 26 July 2024 (08:08:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0785.v1

3D Simulation-Driven Design of a Microfluidic Immunosensor for Real-Time Monitoring of Sweat Biomarkers

Nessrine JEBARI, Elisabeth Dufour-Gergam, Mehdi AMMAR

Subject: Engineering, Bioengineering Keywords: microfluidic immunosensor; 3D simulation; capacitive sensing; magnetofluidic manipulation; real-time monitoring

Online: 10 July 2024 (11:54:40 CEST)

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Preprint REVIEW | doi:10.20944/preprints202406.0270.v1

The Role of NtproBNP in Diagnosis and Treatment of Heart Failure with Preserved Ejection Fraction, Its Not Always a Seek and Hide Game

Christina Chrysochoou, Konstantinos Konstantinou, Kostas Tsioufis

Subject: Biology And Life Sciences, Life Sciences Keywords: heart failure; NPs; HFpEF; diet

Online: 6 June 2024 (03:05:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1832.v1

Instructional Videos for Students at Dental Medicine: Rules of Design and Correlations with their Habits as Internet Consumers

Cristina Gena Dascalu, Claudiu Topoliceanu, Magda Ecaterina Antohe

Subject: Medicine And Pharmacology, Other Keywords: instructional videos; medicine students; dental students; e-learning; data clustering

Online: 28 April 2024 (10:23:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0756.v1

Study on the Relationship between Strength and Failure Area of Concrete Specimens under Complex Loading Conditions

Xinyu Liang, Wenhai Li, Zengbiao Wu

Subject: Engineering, Architecture, Building And Construction Keywords: Concrete material; Stress state; Strength; Damaged area

Online: 11 April 2024 (09:07:21 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201608.0037.v1

Measurement of Heat-Flux of New Type Façade Walls

Todorka Samardzioska, Roberta Apostolska

Subject: Engineering, Civil Engineering Keywords: energy efficient building; heat flux; thermal transmittance; in situ measurement

Online: 4 August 2016 (08:09:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.0356.v1

Predicting the Choice of Online or Offline Shopping Trips Using a Deep Neural Network Model and Time Series Data: A Case Study of Tehran, Iran

MohammadHanif Dasoomi, Ali Naderan, Tofigh Allahviranloo

Subject: Engineering, Transportation Science And Technology Keywords: online shopping trip; offline shopping trips; deep neural network model; e-commerce and transportation; factors affecting shopping trip choice; sustainable development

Online: 6 September 2023 (14:28:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.0938.v1

Examining the Relationships Between the Incidence of Infectious Diseases and Mood Disorders: An Analysis of Data From the Global Burden of Disease Studies, 1990-2019

Ravi Philip Rajkumar

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: major depressive disorder; bipolar disorder; infectious diseases; upper respiratory infections; lower respiratory infections; lung-brain axis; gut-brain axis

Online: 13 July 2023 (12:23:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202201.0434.v1

Permanently Installed Terrestrial Laser Scanner And Synthetic Aperture Radar Data: Evaluation Of Correlation Factor Through Time Series Analysis On Coastal Area Under Varying Environmental Conditions

Valeria Di Biase, Mieke Kuschnerus, Roderik C. Lindenbergh

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Terrestrial Laser Scanner; SAR; coastal environment; weather effect; surface roughness.

Online: 28 January 2022 (11:18:54 CET)

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In the past years, our knowledge of coastal environments has been enriched by remotely sensed data. However, to successfully extract information from a combination of different sensors systems, it should be understood how these interact with the common coastal environment. In this research we co-analyze two sensor systems: Terrestrial Laser Scanning (TLS) and satellite based Synthetic Aperture Radar (SAR). TLS shows large potential for examining coastal processes thanks to the possibility to retrieve repeated, accurate and dense topographic information in a rapid and non-invasive manner. However, TLS presents some limits due to its high economic costs and limited field of view. SAR systems are among the most used active remote sensor system for Earth Observation. Despite their relatively low resolution, SAR systems provide the ability to monitor and map coastal areas with complete, repeated and frequent coverage, penetrating through clouds and providing all weather monitoring. Moreover, Sentinel-1 SAR images are freely available. The availability of a permanently installed TLS system (PLS, Permanent Laser Scanner) allows us, to extensively compare Sentinel-1 SAR data and topographic laser scans during different conditions on a sandy beach. PLS data are compared with simultaneous Sentinel-1 SAR images in order to investigate the combined use of PLS and SAR in coastal environments. The purpose of this comparison is the investigation of a possible relation between PLS and SAR data: knowing their relation, SAR dataset could be correlated to beaches characteristics. Meteorological and surface roughness have also been taken into consideration in the evaluation of the correlation between PLS and SAR data. The permanently installed laser scanner for the present study is located in Noordwijk (the Netherlands). A generally positive but low correlation exists between the two variables. When considering weather phenomena, their correlation increases and shows a dependence on wind directions and speed. The correlation with the surface roughness, evaluated in terms of root-mean squared height, also depends on specific wind speed and directions.

Preprint ARTICLE | doi:10.20944/preprints202106.0355.v1

Treatment Adherence Status of the TB Patients Notified from Private Sector and its Associated Factors: Findings of a Secondary Data Analysis from West Bengal, India

Abhijit Dey, Arista Lahiri, Sweety Suman Jha, Vivek Sharma, Shanmugam Parthiban, Arup Kumar Chakrabartty

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: TB; Treatment Adherence; Private Sector; Defaulter; LTFU; THALI

Online: 14 June 2021 (11:45:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202103.0002.v1

Relative Dating of Moraines from the Arid Part of Altai: Applying of Rock Weathering and Colonization by Biota Data within the Framework of the Method

Dmitrii A. Ganyushkin, Sofya N. Lesovaya, Dmitrii Y. Vlasov, Gennady P. Kopitsa, László Almásy, Kirill V. Chistyakov, Elena G. Panova, Ekaterina Derkach, Anastasiya Alekseeva

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: biota colonization; weathering; rock porosity; Pleistocene moraines; moraine relative dating

Online: 1 March 2021 (12:30:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints202410.0091.v1

Solvability of a Boundary Value Problem for One-Dimensional Motion of a Granular Matter

Irina Akhmerova, Alexander Papin, Artyom Pravdivtsev, Alla Ustyuzhanova

Subject: Computer Science And Mathematics, Applied Mathematics Keywords:

granular temperature; density; granular material; solvability

Online: 2 October 2024 (08:08:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.2455.v1

Effects of Soil Compaction Stress Combined with Drought on Soil Pore Structure, Root System Development, and Maize Growth

Xiangming Zhu, Wei Peng, Qingyang Xie, Enhua Ran

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: maize; soil compaction; drought; X-ray computed tomography (XCT); soil pore characteristics

Online: 1 October 2024 (03:41:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.1420.v1

Decision Analysis Approaches on the Collection Methods of Polyethylene Terephthalate Waste

Johnson A. Oyewale, Lagouge K. Tartibu, and Imhade P. Okokpujie

Subject: Engineering, Mechanical Engineering Keywords: PET waste; AHP; TOPSIS; VIKOR; entropy weights; equal weights

Online: 19 September 2024 (07:39:23 CEST)

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The rising challenge of polyethylene terephthalate (PET) waste necessitates efficient collection methods to mitigate environmental impacts. The Analytic Hierarchy Process (AHP) is one of the Multi-Criteria Decision Analysis (MCDA) approaches utilized in this study. The Technique for Order of Preference by Similarity to the Ideal Solution (TOPSIS) was used to rank each alternative according to the objective weight that AHP had produced. Also, sensitivity analysis was performed to determine how robust the findings were when considering equal weights and entropy weights to maximize PET waste collection techniques. The alternative achieved the objective of obtaining the best collection method, Threshold Plastic Bottle Waste Collection (Tpbw), out of all the three alternatives considered. Another MCDA approach, VIseKriterijumska Optimizacija I Kompromisno Resenje (VIKOR), was used to compare the results and validate the ranking result achieved by the TOPSIS method. The VIKOR technique's validation of the TOPSIS approach showed that the outcomes were highly consistent. Data for the study were gathered from the archives of waste management companies on possible practices of plastic waste collection addressing costs, environmental impacts, social acceptance, feasibility, and efficiency. The findings provide a prioritized framework for enhancing PET waste collection strategies, contributing to sustainable waste management. Many criteria are considered when deciding the best collecting method for PET waste recycling, making it challenging. By using criteria importance, multi-criteria decision analysis (MCDA) was applied in this study, and the objective weight of the criteria was determined using the analytic hierarchy process (AHP). The five criteria considered in this study are Initial investment cost, Operational cost, Transportation cost, Environmental risk, Employment potential, and the objective weights allocated to them. AHP results 0.4952, 0.1997, 0.1565, 0.0870, and 0.0616 are respectively determined.

Preprint ARTICLE | doi:10.20944/preprints202409.0324.v1

Optimal Design and Analysis of Wide-band Near-infrared Hybrid Dielectric Gratings with High Transmission Efficiency

Ye Wang, Yongyi Chen, Li Qin, Lijun Wang

Subject: Engineering, Electrical And Electronic Engineering Keywords: Near-infrared; Transmission grating; Multilayer dielectric; Fabrication Tolerance

Online: 4 September 2024 (16:20:20 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.2262.v1

The Relations between COVID-19, Country Governance, and CSR: An International Comparative Study

Dimitrios Vortelinos, Ioannis Passas, Christos Floros, Alexandros Garefalakis

Subject: Business, Economics And Management, Finance Keywords: ESG; CSR; Covid-19; country governance; Europe; non-Europe; controversies

Online: 29 July 2024 (09:54:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0740.v1

The Importance of Landscape Design in Hospital Settings – Results of a Pilot Study in Poland

Monika Trojanowska, Joanna Matuszewska

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: hospital design; landscape design; architecture; urban design; landscape architecture; healing gardens; patients' preferences

Online: 10 July 2024 (12:56:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0152.v1

Self-Cleaning Solar Mirrors Coatings: From the Laboratory Scale to Prototype Field Tests

Anna Castaldo, Emilia Gambale, Giuseppe Vitiello, Giuseppe Cara

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: solar mirrors; self-cleaning; coatings; sputtering; AlN; prototype; test on field

Online: 2 July 2024 (02:57:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1991.v1

Regulatory Threshold of Soil and Water Conservation Measures on Runoff and Sediment Processes in the Sanchuan River Basin

Ding Xinhui, Liu Xiaoying, Liu Guangquan, Xiao Peiqing

Subject: Environmental And Earth Sciences, Ecology Keywords: runoff reduction effect; sediment reduction effect; threshold

Online: 28 June 2024 (12:07:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1860.v1

Physical, Chemical and Antibacterial Characterization of Hand Sanitizer Lotion Made on Brown Seaweed (Scytosiphon lomentaria)

Radipta Lailatussifa, Endang Trowulan, Lego Suhono, Sutrisno Sutrisno

Subject: Biology And Life Sciences, Life Sciences Keywords: Hand Sanitizer Lotion; S. lomentaria; Antibacterial; Total Phenol; Antioxidant; Emulsion Type

Online: 26 June 2024 (14:43:45 CEST)

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Preprint REVIEW | doi:10.20944/preprints202406.1367.v1

Beyond Anticoagulation: A Comprehensive Review of Non-Vitamin K Oral Anticoagulants (NOACs) in Inflammation and Protease-Activated Receptor Signaling

Shirin Jannati, Rajashree Patnaik, Yajnavalka Banerjee

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: NOAC; Anti-Inflammation; Protease-Activated-Receptor Signaling; Factor Xa; Thrombin.

Online: 20 June 2024 (00:16:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.2111.v1

Characteristics and Influencing Factors of Landscape Pattern Gradient Transformation of Small-Scale Agroforestry Patches (SAP) in Mountain Cities

Canhui Cheng, Zhong Xing, Lin Ye, Junyue Yang, Zhuoming Xie

Subject: Environmental And Earth Sciences, Ecology Keywords: mountain cities; small-scale agroforestry patches; urban-rural gradient; landscape pattern; woodland patches; cultivated land patches; garden land patches; influencing factors

Online: 31 May 2024 (09:10:12 CEST)

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Questions：SAP in mountainous cities of China serve as crucial carriers for species and wild food, constituting potential green infrastructure. These patches should be recognized as locally specific resources. This study investigates the transformation characteristics of the landscape patterns of SAP, along with their elements, across urban-rural gradients, providing foundational support for the planning of conservation and utilization strategies. Location: Yongchuan area of Chongqing in southwest China. Methods: The study investigated urban-rural gradient-based transformation of SAP. A four-direction transect space was selected and divided into uniform sample squares. Fragstats 4.3 calculated the landscape index of SAP, and Spearman correlation coefficients in SPSS were used to evaluate the influence of landform and artificial factors on agroforestry patch transformation. Results: 1) Patch area (PA), Plaque density (PD), and CLUMPY of SAP systematically transform, showing increased SAP areas and higher connectivity with greater distance from the city, resulting in reduced patch fragmentation. However, Edge density (ED) and Largest plaque index (LPI) exhibit irregular transformation patterns. 2) With increased distance from the city, woodland patch area and connectivity increase, leading to decreased fragmentation, dispersal, and lower fractal dimensions. Conversely, Cultivated land follows the opposite trend. garden land patch area, fractal dimension, fragmentation, and dispersal all increase, while connectivity decreases. 3) Landscape pattern transformations of SPA are significantly influenced by artificial factors. Woodland patches are influenced similarly by landform and artificial factors. In contrast, cultivated land and garden land patches are more significantly impacted by artificial factors. Conclusions: SAP exhibit differentiated conservation and utilization measures across urban-rural gradients. Small patches located far from urban centers may benefit from systematic conservation measures to prevent further fragmentation and erosion in peri-urban areas.

Preprint ARTICLE | doi:10.20944/preprints202405.1219.v1

Exploring Cyclists Behavior, Traffic Safety Literacy, and Crash Occurrence in Latvia

Katrina Volgemute, Zermena Vazne, Sergio A. Useche

Subject: Social Sciences, Behavior Sciences Keywords: cycling; behavior; risk perception; traffic safety; crash occurrence

Online: 20 May 2024 (12:37:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0126.v1

Senior High School Students’ difficulties with Geometry Topics

Christian Kwame Kpotosu, Stanley Amegbor, Bismarck Mifetu, Raymond Bessa Kwadzo Ezah

Subject: Social Sciences, Education Keywords: chord; Circle theorems; geometry; geometry difficulties; geometry topics; senior high schools; tangents; perpendicularity

Online: 2 May 2024 (10:11:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.2001.v1

Analysis and Reconstruction Method of Spatial Characteristics of Traditional Chinese Villages Based on Parameterization

Yong Fan, Xuan Li, Wen-jie Xiao, Di Wang

Subject: Social Sciences, Geography, Planning And Development Keywords: traditional Chinese villages; spatial feature extraction; parametric design; digital generative design; village reconstruction; cultural heritage preservation

Online: 30 April 2024 (11:55:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1853.v1

Visual Odometry in GPS Denied Zones for Fixed-Wing UAV with Reduced Accumulative Error Based on Satellite Imaginary

Pablo Mateos-Ramirez, Javier Gomez-Avila, Carlos Villaseñor, Nancy Arana-Daniel

Subject: Computer Science And Mathematics, Computer Vision And Graphics Keywords: Unmanned Aerial Vehicle; Geopositioning; visual odometry; Aerial Imagery; feature extraction

Online: 29 April 2024 (04:08:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0612.v1

Consumer Information Disclosing Strategy within Consumer Misrepresentation

Mingyue Zhong, Yan Cheng, Shu-e Mei, Weijun Zhong

Subject: Social Sciences, Behavior Sciences Keywords: misrepresentation; privacy protection behavior; information disclose; personalized service

Online: 11 March 2024 (13:13:35 CET)

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Preprint REVIEW | doi:10.20944/preprints202402.1340.v1

Progress in the Application of 3D Skin Models for Cosmetic Assessment

Chen Shuxian, Wang Qin, Ding Yunlian, Li Shenjia, Yu Ruilian

Subject: Chemistry And Materials Science, Biomaterials Keywords: 3D skin model; Cosmetics; In vitro assessment; Efficacy evaluation

Online: 23 February 2024 (09:22:25 CET)

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