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Preprint ARTICLE | doi:10.20944/preprints202309.0543.v1

Research and Application of a High-pressure, Large-flow and High-water-based Mining Digitally Controlled Unloading Valve

Xiaochun Zhang, Jiyun Zhao

Subject: Engineering, Control And Systems Engineering Keywords: mining unloading valve; high pressure; large flow; high-water-based fluid; digitally controlled unloading valve

Online: 8 September 2023 (05:09:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.1004.v1

Cuban Policosanol (Raydel®) Exhibited Potent Anti-inflammatory Activity in the Liver and Protection of the Ovary and Testis with an Improvement of Blood Lipid Profile by 12 Weeks Supplementation in Hyperlipidemic Zebrafish: Comparison Study of Efficacy with Three Chinese Policosanols

Kyung-Hyun Cho, Ji-Eun Kim, Seung Hee Baek

Subject: Biology And Life Sciences, Life Sciences Keywords: Policosanol; high cholesterol diet; high-density lipoproteins; apoA-I; inflammation; interleukin-6; liver; testis; ovary

Online: 14 July 2023 (09:27:04 CEST)

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Although many policosanols from different sources, such as sugar cane, rice bran, and insects, have been marketed worldwide, there has been no comparative study of the in vivo efficacy using a hyperlipidemic animal model. This study compared the efficacy of treating dyslipidemia with four different policosanols, including one sugar cane wax alcohol from Cuba (Raydel®) and three policosanols from China (Xi’an Natural sugar cane, Xi’an Realin sugar cane, and Shaanxi rice bran) in hyperlipidemic zebrafish. After 12 weeks of consumption of each policosanol (final 0.1% in diet, wt/wt) and high cholesterol diet (HCD, final 4%, wt/wt) in a tetrabit, the Raydel policosanol group and Xi’an Natural policosanol group showed the highest survivability of approximately 81%, whereas the Xi’an Realin policosanol group and Shaanxi policosanol group showed 57% and 67% survivability, respectively. Among five HCD groups, the Raydel policosanol group showed the lowest serum total cholesterol (TC, p<0.001 versus HCD control) and triglyceride (TG, p<0.001 versus HCD control) with the highest percentage of high-density lipoproteins (HDL)-C in TC. The Raydel policosanol group also showed the lowest serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels with the least infiltration of inflammatory cells and interleukin-6 production in hepatocytes. In the ovary, the Raydel policosanol group also showed the highest contents of mature vitellogenic oocytes with the lowest production of reactive oxygen species and cellular apoptosis in ovarian cells. In the testis, the Raydel policosanol group also showed the healthiest morphology for spermatogenesis with the least interstitial area and reactive oxygen species (ROS) production in testicular cells. In conclusion, 12 weeks of Raydel policosanol consumption resulted in remarkable improvement of the blood lipid profile, amelioration of inflammation in the liver, and enhancement of the cell morphology in the ovary and testis with the highest survivability under the HCD.

Preprint ARTICLE | doi:10.20944/preprints202007.0120.v1

Microstructure and Composition Evolution of a Fused Slurry Silicide Coating on MoNbTaTiW Refractory High-entropy Alloy in High-temperature Oxidation Environment

Jiesheng Han, Bo Su, Junhu Meng, Aijun Zhang, Youzhi Wu

Subject: Chemistry And Materials Science, Surfaces, Coatings And Films Keywords: refractory high-entropy alloys; fused slurry method; silicide coating; Si-20Cr-20Fe; high-temperature oxidation

Online: 7 July 2020 (09:43:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202004.0106.v1

Meta-Analysis of Fiber Impact on Mechanical Properties of Ultra-High Performance Concrete

Faiq M. Al-Zwainy

Subject: Engineering, Civil Engineering Keywords: Meta-analysis; Effect size; Precision; Ultra-high strength concrete; Ultra-high strength fiber reinforced concrete

Online: 7 April 2020 (13:28:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201909.0322.v1

Comparative Analysis of Compiler Performances and Program Efficiency

Paul Tawo Bukie, Chinedu Leonard Udeze, Iwara Ofem Obono, Edim Bassey Edim

Subject: Computer Science And Mathematics, Computer Science Keywords: java virtual machine (jvm); high level programming languages; high performance computing (hpc); php framework; compiler

Online: 29 September 2019 (05:01:46 CEST)

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Preprint CONCEPT PAPER | doi:10.20944/preprints202106.0486.v1

The Oxygen Transport Triad in High Altitude Pulmonary Edema: a Perspective from the High Andes

Gustavo Zubieta-Calleja, Natalia Zubieta-DeUrioste

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: high altitude, chronic hypobaric hypoxia, physiologic adaptation, travel to high altitude cities, high altitude physiology, pulmonary hypertension, lung disease, hemoglobin, tolerance to hypoxia, oxygen content.

Online: 18 June 2021 (15:22:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0552.v1

A Dimensional Analysis for Cost Optimization and Cost-Effective Carbon Capture: A Comparative Study of Hybrid Post-Combustion Configurations in Natural Gas Power Plants

Donald Obi, Samuel Onyekuru, Anselem Orga

Subject: Environmental And Earth Sciences, Sustainable Science And Technology Keywords: CO2 capture; post-combustion carbon capture; hybrid configurations; design; simulation; economic evaluations; dimensional analysis

Online: 8 August 2024 (13:19:29 CEST)

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Carbon capture, utilization, and storage (CCUS) considered a the key strategy for reducing the emissions of anthropogenic carbon dioxide from power generation plants, can be achieved by three main technologies: oxy-fuel combustion, pre-combustion, and post-combustion capture. Post-combustion carbon capture (PCC), where CO2 is removed after the fuel burning, is a crucial solution for reducing greenhouse gas emissions from natural gas power plants (NGPPs). However, high costs and energy penalties associated with PCC technologies hinder their widespread adoption. Recent advancements in hybrid PCC configurations have shown promise in improving efficiency and reducing costs. In effect, six PCC hybrid configurations below were identified as feasible process routes: • 2S-AB +AD: Two-stage Absorption + Adsorption hybrid • 2S-AB +MB: Two-stage Absorption + Membrane hybrid • 2S-AD +AB: Two-stage Adsorption + Absorption hybrid • 2S-AD +MB: Two-stage Adsorption + Membrane hybrid • 2S-MB +AB: Two-stage Membrane + Absorption hybrid • 2S-MB +AD: Two-stage Membrane + Adsorption hybrid Each hybrid has its own technical and economic challenges that need to be investigated in order to identify the best technique for carbon capture. In this paper, we performed Aspen Hysys design simulation of the six hybrids PCC configurations and also their economic evaluations using parameters like investment costs, operating costs, net present value, and rate of return, culminating in the use of three assessment parameters namely, levelized cost of electricity (LCOE), carbon emission intensity (CEI) and cost of carbon avoidance (COA), to evaluate the six hybrids PCC configurations and to determine the most viable option. Overall, it was found by dimensional analysis that the post combustion carbon capture using 2S-MB +AB: Two-stage Membrane + Absorption hybrid is the most viable for capturing CO2 from power generation plants and is hereby recommended. However, the choice of materials (membranes and absorbents) needs to be evaluated so as determined the best optimal configuration for commercialization.

Preprint ARTICLE | doi:10.20944/preprints202405.1453.v1

A New Approach for the Circular Inversion in l1- Normed Spaces

Temel Ermiş, Ali Osman Şen, Johan Gielis

Subject: Computer Science And Mathematics, Geometry And Topology Keywords: Finite-Dimensional Banach Spaces; Minkowski Geometry; Metric Geometry; l1-Norm; Manhattan Metric, Taxicab Metric

Online: 22 May 2024 (15:12:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1358.v1

A Pi-Theorem-Based Advanced Scaling Methodology for Similarity Assessment of Marine Shafting Systems

Georgios N. Rossopoulos, Christos I. Papadopoulos

Subject: Engineering, Marine Engineering Keywords: Pi-Theorem; dimensional analysis; marine shafting systems; journal bearing performance; comparative analysis; similarity assessment

Online: 19 April 2024 (15:56:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0577.v1

Optical Color Image Encryption Algorithm Based on Two‐Dimensional Quantum Walking (OCT)

Guohao Cui, Xiaoyi Zhou, Hao Wang, Wentao Hao, Anshun Zhou, Jianqiang Ma

Subject: Computer Science And Mathematics, Security Systems Keywords: Optical color image incryption; Image incryption; Two-dimensional quantum walking; Double random phase encoding

Online: 8 April 2024 (14:37:22 CEST)

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Preprint REVIEW | doi:10.20944/preprints202403.1369.v1

Virtual Hemodynamic Assessment of Coronary Lesions: The Advent of Functional Angiography and Coronary Imaging

Sotirios Nikopoulos, Michael Papafaklis, Panagiota Tsompou, Panagiotis K Siogkas, Antonis I. Sakellarios, Spyros Sioros, Dimitrios I. Fotiadis, Katerina K Naka, Dimitrios N Nikas, Lampros K Michalis

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: Cardiovascular disease; Three-dimensional reconstruction; Virtual functional assessment; Medical imaging; Angiography; Computational fluid dynamics

Online: 22 March 2024 (11:52:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.1657.v1

Effective Placement Strategies for Portable Fishways in Agricultural Drainage Canals: A Numerical Investigation

Shigeya Maeda, Yuri Yoshida, Kanuka Yoshinari, Naoki Takahashi

Subject: Environmental And Earth Sciences, Environmental Science Keywords: portable fishway; hydraulic environment; agricultural drainage canal; chute; effective positioning; two-dimensional hydrodynamic simulation

Online: 25 October 2023 (12:54:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1565.v1

Short-Term Photovoltaic Power Forecasting Based on a Feature Rise-Dimensional Two-Layer Ensemble Learning Model

Hui Wang, Su Yan, Danyang Ju, Nan Ma, Jun Fang, Song Wang, Haijun Li, Tianyu Zhang, Yipeng Xie, Jun Wang

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: photovoltaic power forecasting; deterministic forecasting; probability interval forecasting; ensemble learning; feature rise-dimensional method

Online: 22 September 2023 (11:37:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.1331.v1

Calculation of Thermodynamic Quantities of 1D Ising Model with Mixed Spin-(s,(2t-1)/2) by Means of Transfer Matrix

Hasan Akin

Subject: Computer Science And Mathematics, Computational Mathematics Keywords: one-dimensional Ising model with mixed spin; free energy; entropy; magnetization; susceptibility; phase transition

Online: 18 August 2023 (07:29:21 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202301.0141.v1

Anatomical Study of Type Classification and Surface Area of Attachment Sites for Tibialis Anterior Tendon

Tomoki Hirai, Mutsuaki Edama, Ryoya Togashi, Haruki Osanami, Rina Saito, Koyo Kato, Mayuu Shagawa, Chie Sekine, Hirotake Yokota, Ryo Hirabayashi, Tomonobu Ishigaki, Hiroshi Akuzawa, Yuki Yamada, Taku Toriumi, Ikuo Kageyama

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: tibialis anterior tendon; attachment site area; three-dimensional; medial cuneiform bone; first metatarsal bone

Online: 9 January 2023 (06:36:49 CET)

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Preprint ARTICLE | doi:10.20944/preprints202301.0015.v1

Improving the Directionality of Low-Frequency Acoustic Radiation by a Finite Array of Quadrupolar Sources with Acoustic Metamaterials

Qinglei Zeng, Shenlian Gao, Yun Lai, Xiaozhou Liu

Subject: Physical Sciences, Acoustics Keywords: Acoustic metamaterials; F-P resonance effect; Two-dimensional Helmholtz resonator; Linear array; Dipole; Quadrupole

Online: 3 January 2023 (07:58:17 CET)

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Preprint ARTICLE | doi:10.20944/preprints202108.0203.v1

The Finite Size Lyapunov Exponent and the Finite Amplitude Growth Rate

Thomas Meunier, J.H. LaCasce

Subject: Environmental And Earth Sciences, Oceanography Keywords: Finite size Lyapunov Exponent; Finite amplitude growth rate; Two-dimensional turbulence; Lagrangian fluid dynamics

Online: 9 August 2021 (15:07:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202107.0417.v1

U-Shape by Quadratic Equation: A Best-fit for Modelling Hemodynamic Changes in the DCCS Task

Hui Li, Dandan Wu, Jinfeng Yang, Sha Xie, Jiutong Luo, Chunqi Chang

Subject: Social Sciences, Psychology Keywords: Pad use; Executive Function; fNIRS Evidence; Dimensional Change Card Sort Task (DCCS) task; Preschoolers

Online: 19 July 2021 (15:05:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202104.0188.v1

Tablet Use Affects Preschoolers’ Executive Function: fNIRS Evidence from the Dimensional Change Card Sort Task

Hui Li, Dandan Wu, Jinfeng Yang, Jiutong Luo, Sha Xie, Chunqi Chang

Subject: Social Sciences, Psychology Keywords: Pad use; Executive Function; fNIRS Evidence; Dimensional Change Card Sort Task (DCCS) task; Preschoolers

Online: 7 April 2021 (11:08:12 CEST)

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Preprint HYPOTHESIS | doi:10.20944/preprints202003.0304.v1

Ab Initio Modelling the Structure of Proton-Sensing G-Protein Coupled Receptor GPR151

Wei Li

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: Ab Initio modelling; three-dimensional structure; proton-sensing G-protein coupled receptor (GPCR); GPR151

Online: 20 March 2020 (04:25:00 CET)

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Preprint ARTICLE | doi:10.20944/preprints201812.0207.v2

Classical and Quantum Kepler's Third Law of N-Body System

Bohua Sun

Subject: Physical Sciences, Quantum Science And Technology Keywords: Kepler's third law; n-body system; periodic orbits; dimensional analysis, classical and quantum mechanics

Online: 31 January 2019 (11:52:22 CET)

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Preprint ARTICLE | doi:10.20944/preprints202407.1961.v1

Investigation and Suggestions on the Implementation Status of Credit System in High Schools of Zhejiang in China

Chengtian Liang, Enqi Xu

Subject: Social Sciences, Education Keywords: High School; Credit system; Credit acquisition

Online: 24 July 2024 (17:49:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1526.v1

Preliminary Analysis of Protein Catalytic Ability and Catalytic Structure

Zheming Cao

Subject: Physical Sciences, Biophysics Keywords: protein; high-energy state; catalysis; AlphaFold

Online: 18 July 2024 (16:45:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1607.v1

Properties of a Pressureless Sintered 2Y-TZP Material Combining High Strength and Toughness

Frank Kern, Bettina Osswald

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: zirconia; high toughness; microstructure; phase composition

Online: 24 May 2024 (08:38:08 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1536.v1

Off Label Use of Tenecteplase in the Management of High-Risk Pulmonary Embolism

Badre El Boussaadani, Nabil Zergoune, Salma Mayoussi, Houssam Bendoudouch, Loubna Hara, Amine Ech-chenbouli, Zainab Raissuni

Subject: Medicine And Pharmacology, Clinical Medicine Keywords: pulmonary embolism; high-risk; thrombolysis; tenecteplase

Online: 24 May 2024 (02:55:36 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202402.1610.v1

Exceptional Lithography Sensitivity Boosted by Hexafluoroisopropanols in Photoresists

Junjun Liu, Dong Wang, Yitan Li, Haihua Wang, Huan Chen, Qianqian Wang, Wenbing Kang

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: Hexafluoroisopropanol; high-sensitivity; photoresist; photoacid generation

Online: 28 February 2024 (08:04:18 CET)

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Preprint REVIEW | doi:10.20944/preprints202307.1092.v1

Survey on Fungi in Antarctica and High Arctic Regions, and Their Impact on Climate Change

Masaharu Tsuji

Subject: Environmental And Earth Sciences, Ecology Keywords: Antarctica; High Arctic; fungi; climate change

Online: 17 July 2023 (09:48:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202211.0353.v1

The Relationship between Association between Blood Pressure and Risk of Cancer Development

Nikolaos Tzenios, Mary Tazanios, Mohamad Chahine

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: high blood pressure; Cancer; malignancies; hypertension

Online: 18 November 2022 (10:05:11 CET)

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Background of the Study: We investigated the link between hypertension and cancer since it has been suggested that hypertension may raise the long-term risk of cancer. Previous large observational cohort studies found that greater blood pressure (BP) was related to a higher risk of cancer. Mendelian randomization (MR) was utilized to produce less confounded blood pressure estimates (BP) on overall and site-specific malignancies. The study aims to draw conclusions on the relationship between high blood pressure and cancer. Methods: Studies on high blood pressure and various malignancies are inconclusive, except for renal cell carcinoma. However, given that most meta-analyses only contained a limited number of trials, some relative risks had small to moderate magnitudes, and several may have been impacted by residual confounding, careful interpretation is necessary. The study was conducted using the meta-analysis technique. Cochran's Q test and I2 test were used to assess statistical heterogeneity between studies in the current investigation for research involving two or more cause and outcome combinations. Results: Positive correlations were also reported between high blood pressure and esophageal adenocarcinoma, squamous cell carcinoma, liver, and squamous cell carcinoma. However, most studies lacked multivariable adjustments. Physical and numerical risk of cardiovascular disease is linked to bowel cancer but no other cancers. According to a meta-analysis, hypertensive persons could also be at increased danger of gastrointestinal and breast cancer. Most meta-analyses comprised several trials with moderate or mild hazard ratios.ConclusionDifferent types of cancers have been noted to be directly caused by hypertension. In addition, some treatments have also been associated with the side effects of cancer treatments to cause hypertension. Women facing hypertension have an increased risk of getting breast cancer. Although some cancers showed a real relationship with hypertension, others had no connection at all.

Preprint ARTICLE | doi:10.20944/preprints202104.0598.v1

Influence of Chromium Concentration on the Abrasive Wear Of Ni-Cr-B-Si Coatings Applied by High-Velocity Oxygen Fuel

Zhetcho Doinov Kalitchin, Mara Krumova Kandeva, Yana Petrova Stoyanova

Subject: Chemistry And Materials Science, Biomaterials Keywords: high-velocity oxygen fuel; chromium; abrasion

Online: 22 April 2021 (09:24:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202104.0493.v1

Integral Order Photonic RF Signal Processors Based on Kerr Micro-combs

Mengxi Tan, Xingyuan Xu, David Moss

Subject: Engineering, Automotive Engineering Keywords: microcombs; filters; high bandwidth; RF photonics

Online: 19 April 2021 (13:51:34 CEST)

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Preprint REVIEW | doi:10.20944/preprints202104.0178.v1

Dyad Model as a Caring Innovation in High Risk Pregnancy

Sri Wahyuni, Moses Glorino Rumambo Pandin

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Dyad Model; Caring; High Risk Pregnancy

Online: 6 April 2021 (13:30:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202104.0162.v1

Tunable Broadband RF Photonic Fractional Hilbert Transformer Based on a Soliton Crystal Microcomb

Mengxi Tan, Xingyuan Xu, David Moss

Subject: Engineering, Automotive Engineering Keywords: microcombs; filters; high bandwidth; RF photonics

Online: 6 April 2021 (10:06:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201805.0069.v3

Investigation of Constraints to be Occured in Participation to the Leisure Activities of High School Students: Sample of Turkey

Cihan Ayhan, Nurullah Emir Ekinci, Ilimdar Yalcin, Sihmehmet Yigit

Subject: Social Sciences, Behavior Sciences Keywords: high school; student; leisure; leisure constraints

Online: 18 May 2018 (05:54:20 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201704.0062.v1

Prognostic Significance of High Survivin Expression in Patients with Gastrointestinal Cancer: A Meta-Analysis

Pingping Xu, Jiajia Lin, Qi Lin, Dexiang Zhu, Wentao Tang, Zhengchuan Niu, Mi Jian, Yanru Wang, Chunmin Liang, Jianmin Xu

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: survivin; high expression; gastrointestinal cancer; prognostic

Online: 11 April 2017 (10:51:06 CEST)

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Preprint REVIEW | doi:10.20944/preprints202312.1070.v1

Highlights of the Magic Florian Goebel Telescopes in the Study of Active Galactic Nuclei

Marina Manganaro, Dijana Dominis Prester

Subject: Physical Sciences, Astronomy And Astrophysics Keywords: γ -ray astrophysics; Active galactic nuclei; very-high-energy gamma rays; non-thermal; high energy astrophysics

Online: 14 December 2023 (08:32:44 CET)

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Preprint REVIEW | doi:10.20944/preprints202008.0496.v1

A Review for Southern Highbush Blueberry Alternative Production Systems

Yang Fang, Gerardo H. Nunez, Mariana Neves da Silva, Douglas A. Phillips, Patricio R. Munoz

Subject: Biology And Life Sciences, Horticulture Keywords: Vaccinium corymbosum interspecific hybrids; high tunnel; greenhouse; plant factory; non-dormant; substrate; container; evergreen; high density

Online: 24 August 2020 (02:56:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201703.0050.v1

Preparation and Evaluation of an Elusive Polymorph of Mefenamic Acid by High Pressure Techniques

Nasir Abbas, Iain Oswald, Colin R. Pulham

Subject: Chemistry And Materials Science, Physical Chemistry Keywords: mefenamic acid; diamond anvil cell; high-pressure; polymorphism; high-pressure crystallization; non-steroidal anti-inflammatory drugs

Online: 8 March 2017 (08:58:38 CET)

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Preprint ARTICLE | doi:10.20944/preprints202410.0606.v1

Investigating the Influence of Body Mass Index on Organs at Risk Doses for Adjuvant HDR Vaginal Cuff Brachytherapy In Patients with Early Stage Endometrial Carcinoma

Alexandra Timea Kirsch-Mangu, Diana Cristina Pop, Alexandru Tipcu, Andrei Rares Avasi, Claudia Ordeanu, Ovidiu Florin Coza, Alexandru Irimie

Subject: Oncology And Oncogenics, Medicine And Pharmacology Keywords: Endometrial cancer; Body mass index; Vaginal cuff brachytherapy; Three-dimensional vaginal cuff brachytherapy; Dosimetry; Obesity

Online: 8 October 2024 (14:55:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0536.v1

Multi-Dimensional Integral Transform with Fox Function in Kernel on Lebesgue-Type Spaces

Sergey Sitnik, Oksana Skoromnik

Subject: Computer Science And Mathematics, Mathematics Keywords: Multi-dimensional integral transform; Fox H-function; Melling transform; weighted space; fractional integrals and derivatives

Online: 8 April 2024 (11:43:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1319.v1

Three-Dimensional Singular Stress Fields and Interfacial Crack Path Instability in Bicrystalline Superlattices of Orthorhombic/Tetragonal Symmetries

Reaz A. Chaudhuri

Subject: Engineering, Mechanical Engineering Keywords: Three-dimensional; Crack; Stress Singularity; bicrystalline superlattice; Orthorhombic; Cubic, Stress Intensity Factor; Energy Release Rate

Online: 22 March 2024 (08:19:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0565.v1

Heart-Cutting Bidimensional Liquid Chromatography for the Simultaneous Analysis of Veterinary Drugs Residues and Nucleotides Monophosphate in Sheep’s Milk

Noelia Caballero-Casero, Diego García-Gómez, José Luis Pérez Pavón, Encarnación Rodríguez-Gonzalo

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: Two-dimensional liquid chromatography; heart-cutting 2D-LC; veterinary drug residue; nucleotides monophosphate; sheep’s milk

Online: 11 March 2024 (08:59:00 CET)

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Preprint ARTICLE | doi:10.20944/preprints202211.0253.v1

Molecular Dynamics and Chain Length of Edible Oil by Low-Field Nuclear Magnetic Resonance

Zijian Jia, Can Liang

Subject: Chemistry And Materials Science, Food Chemistry Keywords: Low-field NMR; Two-dimensional nuclear magnetic resonance; Edible oil; Chain length; rotation correlation time

Online: 14 November 2022 (10:51:18 CET)

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Preprint ARTICLE | doi:10.20944/preprints202012.0223.v1

Three-Dimensional Numerical Visualization And Simulation of Multiphysics in Point Source Dc Magnetometric Resistivity Method

Wenlong Gao, Lei Zhou, Liangjun Yan

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: MMR; abnormal potential method; modified Biot-Savart law; finite difference method; three-dimensional visualization simulation

Online: 9 December 2020 (12:11:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints202008.0031.v2

Mehmet Erbudak, Selim Onat

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: wallpaper groups; planar ornaments; correlation; multi-dimensional scaling; Arabs; Armenian; Byzantium; Islam; Seljuks; cultural interaction

Online: 14 September 2020 (05:42:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201609.0106.v2

New Scientific Contribution on the 2-D Subdomain Technique in Cartesian Coordinates: Taking into Account of Iron Parts

Frédéric Dubas, Kamel Boughrara

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: air- or iron-cored coil; Cartesian coordinates; Fourier analysis; two-dimensional; saturation effect; subdomain technique

Online: 16 January 2017 (04:38:11 CET)

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Preprint ARTICLE | doi:10.20944/preprints202410.0022.v1

Copper Based Graphite Composites and Their Usage as Current Collectors for High Voltage Electric Motors

Radu Mirea, Razvan Ene, Dragos Ene

Subject: Ceramics And Composites, Chemistry And Materials Science Keywords: graphite; carbon composite; high voltage; carbon/metal

Online: 3 October 2024 (07:58:20 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.1497.v1

How to Build a Software Quantum Simulator

Gilberto Javier Díaz, Luiz Angelo Steffenel, Carlos Jaime Barrios, Jean Francois Couturier

Subject: Computer Science And Mathematics, Computer Science Keywords: Quantum Computing; High-Performance Computing; Parallel Computing

Online: 19 September 2024 (10:54:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0783.v1

Characteristics of Patients with Newly Diagnosed High-Grade Advanced Ovarian, Fallopian Tube and Primary Peritoneal Cancer in 2018–2023 and the Impact of Molecular Diagnostics on the Chemotherapy in Clinical Practice

Sonja Millert-Kalińska, Małgorzata Stawicka-Niełacna, Tomczak Lidia, Dominik Pruski, Marcin Przybylski, Karolina Jaszczyńska-Nowinka, Grzegorz Poprawski, Radosław Mądry

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: high-grade ovarian cancer; OC; molecular diagnostics

Online: 10 September 2024 (09:33:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1955.v1

Manufacturing and Functional Characterization of Graphite/Metal Composite Materials for High Voltage Electric Motors

Radu Mirea, Razvan Ene, Dragoș Ene

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: graphite; carbon-metal composites; high voltage; pitch

Online: 28 August 2024 (02:56:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0786.v1

The Confluence Analysis Program: A User-Friendly Tool for Automated Cell Confluence Measurement and Visualization

Abraham Lobsenz, Paul Seidler

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: confluency; bioinformatics; cell segmentation; high-throughput screening

Online: 12 August 2024 (10:24:02 CEST)

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Preprint REVIEW | doi:10.20944/preprints202407.1411.v1

Overview of the Multifaceted Functions of LncRNA HOTAIR in Glioblastoma

Mohammed A. Azab

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: HOTAIR; ncRNAs; GBM; high grade glioma; epigenetics

Online: 17 July 2024 (12:40:12 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202407.0470.v1

Dual-Band Antenna With Pattern and Polarization Diversity

Jungmin Mo, Youngje Sung

Subject: Engineering, Electrical And Electronic Engineering Keywords: High isolation; Pattern-diversity antenna; Polarization diversity

Online: 5 July 2024 (02:50:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0154.v1

Exoscopic Versus Microscopic Surgery in 5-ALA Guided Resection of High Grade Gliomas

Giada Garufi, Alfredo Conti, Bipin Chaurasia, Salvatore Massimiliano Cardali

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: exoscope; microscope; 5-ALA; high grade glioma

Online: 3 May 2024 (07:09:08 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0296.v1

Wenzhou TE: A First-Principles Calculated Thermoelectric Materials Database

Ying Fang, Hezhu Shao

Subject: Physical Sciences, Condensed Matter Physics Keywords: Thermoelectric Materials; Material Databases; High-throughput Computing

Online: 3 April 2024 (12:25:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.1298.v1

Analysis of Attitudes and Practices towards the Influenza Vaccine in High-Risk Adults in Poland

Dorota Kopciuch, Karolina Hoffmann, Krzysztof Kus, Agnieszka Koligat-Seitz, Piotr Ratajczak, Elżbieta Nowakowska, Anna Paczkowska

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: vaccines; influenza; high-risk groups; attitudes; practice

Online: 23 February 2024 (08:30:56 CET)

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Preprint REVIEW | doi:10.20944/preprints202401.0905.v1

Research Status and Development Trend of High-Pressure Water Jet Nozzle

Hongjie Niu, Yuntao Hou, Yafei Lei, Dongyang Li, Yi Yang, Guoyu Song

Subject: Engineering, Mechanical Engineering Keywords: High pressure water jet; Nozzle; Research status

Online: 11 January 2024 (11:00:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0163.v1

A Novel Orthogonally High Isolation CPW Fed UWB MIMO Antenna for IoT Applications

Muhammad Zahid, Nirman Bhowmike, Zaeem Mazhar, Asma Ejaz, Sultan Shoaib, Yasar Amin

Subject: Engineering, Electrical And Electronic Engineering Keywords: UWB; MIMO; Internet of thing; high isolation

Online: 4 December 2023 (07:51:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0124.v1

Outpatient Embedded Palliative Care for Patients With Advanced Thoracic Malignancy: A High-Value Practice

Mary C. Boulanger, Margaret D. Krasne, Ethan K. Gough, Samantha Myers, Ilene S. Browner, Josephine L. Feliciano

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: palliative care; thoracic oncology; high-value care

Online: 4 December 2023 (03:54:29 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.0747.v1

Evaluation of Surface Stabilization and Reinforcement Effect of Fragile Bronzes

JIACHANG CHEN, YIN MAI, LIWEI CHEN, LIANGSHUAI ZHANG, XINZHAN CUI, XIN LIU

Subject: Arts And Humanities, Archaeology Keywords: bronze relics; powder rust; high-permeability; stabilization

Online: 12 October 2023 (02:12:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.2116.v1

Design of a Dual-Band WiFi Antenna Using the Theory of Characteristic Modes and Nested Chinese Characters

Zhonggen Wang, Mingqing Wang, Wenyan Nie

Subject: Engineering, Electrical And Electronic Engineering Keywords: characteristic mode; Chinese characters; WiFi; high isolation

Online: 31 July 2023 (11:42:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202304.0676.v1

mech2d: An Efficient Tool for High-Throughput Calculation of Mechanical Properties for Two-Dimensional Materials

Haidi Wang, Tao Li, Xiaofeng Liu, Weiduo Zhu, Zhao Chen, Zhongjun Li, Jinlong Yang

Subject: Physical Sciences, Condensed Matter Physics Keywords: mechanical properties; 2D materials; high-throughput; DFT.

Online: 21 April 2023 (07:20:16 CEST)

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Preprint REVIEW | doi:10.20944/preprints202204.0228.v1

High Throughput Phenotyping Approach

Anand Kumar, Prashant Kaushik

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: vegetables; high throughput phenotyping; genomic assisted breeding

Online: 26 April 2022 (06:00:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202203.0044.v1

Research on Electromagnetic Radiation Mechanism During Detonation of Energetic Material

Yuanbo Cui, Deren Kong, Jian Jiang, Shang Gao

Subject: Physical Sciences, Radiation And Radiography Keywords: energetic material; plasma; detonation; electromagnetism; high temperature

Online: 2 March 2022 (10:39:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202202.0151.v1

Multiple-Trait Model through Bayesian Inference Applied to Flood-Irrigated Rice (Oryza sativa L)

Antonio Carlos da Silva Junior, Isabela de Castro Sant’Anna, Marco Antônio Peixoto, Lívia Gomes Torres, Michele Jorge Silva, Weverton Gomes da Costa, Camila Ferreira Azevedo, Plinio César Soares, Cosme Damião Cruz

Subject: Computer Science And Mathematics, Analysis Keywords: high-performance; heritable; multi-environments; credibility interval

Online: 10 February 2022 (11:14:21 CET)

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Preprint ARTICLE | doi:10.20944/preprints202110.0330.v1

First Observations of SN 1604 (Kepler's Supernova)

Alessandro De Angelis, selenia broccio

Subject: Physical Sciences, Astronomy And Astrophysics Keywords: Supernova remnants; Stellar evolution; High-energy astrophysics

Online: 22 October 2021 (12:11:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202104.0426.v1

Magnetic Field Alignment, a Perspective in the Engineering of Collagen-Silica Composite Biomaterials

Nicolas Debons, Kenta Matsumoto, Noriyuki Hirota, Thibaud Coradin, Toshiyuki Ikoma, Carole Aimé

Subject: Chemistry And Materials Science, Biomaterials Keywords: bionanocomposites; collagen; high magnetic field; silica particles

Online: 15 April 2021 (18:12:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202103.0122.v1

Performance Enhancement Techniques for Patch Antennas of Small Satellites

Zizung Yoon, Mayank Mayank, Enrico Stoll

Subject: Engineering, Electrical And Electronic Engineering Keywords: satellite communication, antenna optimization, high gain antenna

Online: 3 March 2021 (09:59:04 CET)

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Preprint ARTICLE | doi:10.20944/preprints202103.0104.v1

Chitosan from crabs (Scylla Serrata) Represses Hepato-renal Dysfunctions in Rats via Modulation of CD43 and p53 Expression in High Fat Diet-induced Hyperlipidemia

Regina Ngozi Ugbaja, Kunle Ogungbemi, Adewale Segun James, Peter Folorunsho Ayodele, Olanrewaju Samuel Abolade, Stella Ajamikoko, Eniola Olapeju Atayese, Omowunmi Victoria Adedeji

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Chitosan; Hyperlipidemia; High-fat diet; p53; CD43

Online: 2 March 2021 (16:02:07 CET)

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Preprint ARTICLE | doi:10.20944/preprints202012.0333.v1

ATmospheric LIDar (ATLID): European Space Agency Instrument Ready to Measure Aerosols and Thin Clouds in Atmosphere

João Pereira do Carmo, Geraud de Villele, Kotska Wallace, Alain Lefebvre, Kaustav Ghose, Thomas Kanitz, François Chassat, Bertrand Corselle, Thomas Belhadj, Paolo Bravetti

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: LIDAR; UV laser; high spectral resolution; aerosols

Online: 14 December 2020 (13:11:08 CET)

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Preprint ARTICLE | doi:10.20944/preprints202006.0111.v1

A Novel Family of Quadrupole-Orbitrap Mass Spectrometers for a Broad Range of Analytical Applications

Jan-Peter Hauschild, Amelia Corinne Peterson, Erik Couzijn, Eduard Denisov, Denis Chernyshev, Christian Hock, Hamish Stewart, Ralf Hartmer, Dmitry Grinfeld, Christian Thoeing, Bastian Reitemeier, Arne Kreutzmann, Oliver Lange, Wilko Balschun, Aivaras Venckus, Sebastian Kanngiesser, Alexander Kholomeev, Gregor Quiring, Frank Czemper, Eloy Wouters, Michael Belford, Mathias Mueller, Jens Grote, Tabiwang N. Arrey, Julia Kraegenbring, Kerstin Strupat, Siegrun Mohring, Catharina Crone, Alexander Harder, Aaron Robitaille, Aaron Gajadhar, Khatereh Motamed, Yang Liu, Daniel Lopez Ferrer, Nicolaie Eugen Damoc, Angela Criscuolo, Kristina Srzentic, Ed George, Charles Yang, Ioanna Ntai, Amanda Souza, Andreas Wieghaus, Alexander Makarov

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Orbitrap mass spectrometry; high resolution; accurate mass

Online: 8 June 2020 (10:17:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202002.0459.v1

Oxidation and Characterization of Low Concentration Gas in High-Temperature Reactor

Jinhua Chen, Guangcai Wen, Song Yan, Xiangyun Lan, Lu Xiao

Subject: Engineering, Energy And Fuel Technology Keywords: low concentration; gas; reactor; high-temperature oxidation

Online: 29 February 2020 (09:20:28 CET)

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Preprint ARTICLE | doi:10.20944/preprints201910.0137.v1

An Efficient and High-Resolution Topology Optimization Method Based on Convolutional Neural Networks

Liang Xue, Jie Liu, Guilin Wen, Hongxin Wang

Subject: Computer Science And Mathematics, Mathematics Keywords: topology optimization; convolutional neural network; high-resolution

Online: 12 October 2019 (03:56:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201903.0126.v4

Developing Bid-Ask Probabilities for High-Frequency Trading

Lester Ingber

Subject: Physical Sciences, Applied Physics Keywords: path integral; financial markets; high-frequency trading

Online: 8 May 2019 (08:47:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201904.0238.v1

Assessment of Residual Feed Intake and Its Relevant Measurements in Two Varieties of Japanese Quail (Coturnix coturnix japonica) under High Environmental Temperature

Moataz M. Fathi, Ibrahim Al-Homidan, Tarek A. Ebeid, Ahmed Galal, Osama K. Abou-Emera

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: residual feed consumption; quail; high environmental temperature

Online: 22 April 2019 (11:22:21 CEST)

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Preprint REVIEW | doi:10.20944/preprints201806.0308.v1

Irradiance Variability Quantification and Small-Scale Averaging in Space and Time: A Short Review

Gerald M. Lohmann

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: irradiance variability, high-resolution measurements, increment statistics

Online: 19 June 2018 (17:10:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201804.0075.v1

High Frequency Acceleration Device Effect on Accelerated Aligner Exchange - A Pilot Study

Thomas Shipley

Subject: Medicine And Pharmacology, Dentistry And Oral Surgery Keywords: high frequency; acceleration; vibration; orthodontics; tooth movement

Online: 6 April 2018 (10:57:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201803.0080.v1

Are Changes in Physical Work Capacity Induced by High-Intensity Functional Training Related to Changes in Associated Physiologic Measures?

Derek A. Crawford, Nicholas B. Drake, Michael J. Carper, Justin Deblauw, Katie M. Heinrich

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: high-intensity functional training; work capacity; performance

Online: 12 March 2018 (05:33:23 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.1708.v1

High-Entropy Diborides – Silicon Carbide Composites by Reactive and Non-reactive Spark Plasma Sintering: A Comparative Study

Ekaterina Pakhomova, Giacomo Cao, Roberto Orrù, Sebastiano Garroni, Paolo Ferro, Roberta Licheri

Subject: Chemistry And Materials Science, Ceramics And Composites Keywords: high-entropy borides; silicon carbide; spark plasma sintering; self-propagating high-temperature synthesis; resistance to oxidation; fracture toughness

Online: 22 December 2023 (07:11:43 CET)

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Working Paper ARTICLE

On the Influence of Control Type and Strain Rate on the Lifetime of 50CrMo4

Max Benedikt Geilen, Josef Arthur Schönherr, Marcus Klein, Dominik Sebastian Leininger, Alexander Giertler, Ulrich Krupp, Matthias Oechsner

Subject: Chemistry And Materials Science, Biomaterials Keywords: ultrasonic cyclic testing; frequency effect; strain rate effect; 50CrMo4; SAE 4150; High Cycle Fatigue; Very High Cycle Fatigue

Online: 21 October 2020 (15:18:48 CEST)

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Preprint REVIEW | doi:10.20944/preprints202010.0051.v1

ROS and NO Regulation by Melatonin Under Abiotic Stress in Plants

Miriam Pardo-Hernandez, Maria Lopez-Delacalle, Rosa M Rivero

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: melatonin; ROS; NO; posttranslational modifications (PMTs); abiotic stress; drought; salinity; high temperature; high light; waterlogging; abiotic stress combination

Online: 5 October 2020 (07:48:29 CEST)

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Preprint REVIEW | doi:10.20944/preprints202410.0235.v1

Electron Tomography as a Tool to Study SARS-CoV-2 Morphology

Hong Wu, Yoshihiko Fujioka, Shoichi Sakaguchi, Youichi Suzuki, Takashi Nakano

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: SARS-CoV-2; electron microscopy; transmission electron microscopy; electron tomography; three-dimensional reconstruction; morphogenesis; virus budding

Online: 7 October 2024 (03:09:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1135.v1

Seasonal Dynamics and Three-Dimensional Hydrographic Features of the Eastern Gulf of Thailand: Insights from High-Resolution Modeling and Field Measurements

Tanuspong Pokavanich, Vasawan Worrawatanathum, Kittipong Phattananuruch, Sontaya Koolkalya

Subject: Environmental And Earth Sciences, Oceanography Keywords: Direct rainfall; Gulf of Thailand; Chanthaburi Coastal Current; Monsoon; Three-dimensional modeling; Salinity dynamics; seasonal variability

Online: 17 May 2024 (11:36:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1116.v1

3-Dimensional Soft Tissue Analysis (3DSTA) of Subcrestally Placed Implants: Relating Biologic Stability with Morphologic Achievements.

Won Chiyun

Subject: Medicine And Pharmacology, Dentistry And Oral Surgery Keywords: Biologic Width; Implant; Emergency Profile; Subcrestal; Subcrestal Placement; CBCT; 3-Dimensional Analysis; Junctional Epithelium; Connective Tissue

Online: 17 April 2024 (11:50:28 CEST)

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Objectives (Purpose) This study aims to evaluate the outcomes of the Subcrestally Placed Implant (SPI) technique in single molar cases, focusing on biological stability and aesthetics. It proposes a schematic model to elucidate the interplay between the biological stability of soft tissues and bone around the SPI and the morphological requisites that Implant Abutment Prostheses (IAP) must fulfill to effectively replace natural teeth. Materials and methods I examined 20 cases using the SPI technique with Internal Platform Switching (IPS) design implants for single molar replacements to assess their stability. Routine check-ups utilized plain panoramic X-rays to measure changes in crestal bone on the mesial and distal sides. Additionally, 10 cases with CBCT X-rays taken more than one year after the initial surgery underwent a novel 3-dimensional soft tissue analysis (3DSTA). Measurements included placement depths (PD), soft tissue thickness (STT) at central (cPD, cSTT) and peripheral areas (pPD, pSTT), the length of the Transitional Zone (TZ) on mesial, distal, facial, and lingual aspects, and crestal bone thickness (CBT) at buccal and lingual sites. Results Panoramic analyses showed minimal changes in crestal bone (mean changes of pPD were less than 0.1 mm) over an average period of 3.3 years. Average measurements were as follows: cPD was 1.7 mm, pPD was 2.7 mm, cSTT was 0.2 mm, pSTT was 0.6 mm, TZ length was 3.8 mm, buccal CBT was 3.0 mm, and lingual CBT was 3.7 mm. Conclusions CBCT analyses of the topographical relationships between soft tissue and crestal bone with IAP for SPIs demonstrated stable results over an average 3-year period. The consistency in the relationship between crestal bone and surrounding soft tissue can be ascribed to biological structural integrity. The study classified peri-implant soft tissues into subcrestal and supracrestal (transitional zone – TZ) segments, exploring their characteristics through dimensional measurements and assessing mechanical resistance. Further histological study is needed to identify specific features of each segment.

Preprint ARTICLE | doi:10.20944/preprints202309.1366.v1

Composite Scattering Computation from Multiple Dielectric Targets of One-Dimensional Fractal Sea Surface Using MOM

Chungang Wang, Zichen Wang

Subject: Engineering, Control And Systems Engineering Keywords: the MOM method; composite scattering; dielectric target; floating target; one-dimensional fractal sea surface; numerical simulation

Online: 20 September 2023 (08:54:02 CEST)

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Preprint CASE REPORT | doi:10.20944/preprints202306.0678.v1

Laparoscopic Extended Left Lateral Sectionectomy for Hepatocellular Carcinoma in a Patient with Right-Sided Ligamentum Teres: Case Report and Literature Review

Yuki Adachi, Hiroyuki Takahashi, Tomohiro Yamamoto, Masahiro Hagiwara, Koji Imai, Hideki Yokoo

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: Right-sided ligamentum teres; Three-dimensional computed tomography; Intraoperative ultrasonography; Laparoscopic hepatectomy; Expanded left lateral sectionectomy

Online: 9 June 2023 (07:14:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.0599.v1

Hybrid Functions Approach to Solving Nonlinear Integral Equations in Two Dimensions

Sahar M. Abusalim, Mohamed A. Abdou, Mohamed A. Abdel-Aty, Mohamed E. Nasr

Subject: Computer Science And Mathematics, Mathematics Keywords: Two- dimensional nonlinear integral equation; Banach fixed point theorem; Block-pulse function; Hybrid functions; Legendre polynomials

Online: 9 May 2023 (08:21:21 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202112.0369.v1

Inhomogeneous Phases in the Chirally Imbalanced 2+1-Dimensional Gross-Neveu Model and Their Absence in the Continuum Limit

Laurin Pannullo, Marc Wagner, Marc Winstel

Subject: Physical Sciences, Nuclear And High Energy Physics Keywords: inhomogeneous phases; chiral imbalance; isospin imbalance; 2+1 dimensional field theories; Gross-Neveu model; mean-field

Online: 22 December 2021 (13:15:54 CET)

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Preprint ARTICLE | doi:10.20944/preprints202106.0728.v1

The Spontaneous Pricing Order in the Noncooperative Game of Monopolistic Manufacturer and Many Retailers

Tieyan Si

Subject: Business, Economics And Management, Accounting And Taxation Keywords: Spontaneous order; Price formation; Non-cooperative game theory; Statistical physics; Supply chain; two dimensional Ising model

Online: 30 June 2021 (10:27:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202012.0429.v1

PFDA- FMEA. An Integrated Method Improving FMEA Assessment in Product Design

Pedro Garcia, Luis Perez-Dominguez, David Luviano-Cruz, Jesus Jaime Solano Noriega, Erwing Martinez Gomez, Mauro Callejas-Cuervo

Subject: Engineering, Automotive Engineering Keywords: Product Design (PD); Failure Mode and Effect Analysis (FMEA); Dimensional Analysis (DA); Pythagorean Fuzzy Sets (PFS)

Online: 17 December 2020 (12:02:58 CET)

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Preprint ARTICLE | doi:10.20944/preprints202010.0380.v1

Numerical Analysis for Hydrogen Flame Acceleration during a Severe Accident in the APR1400 Containment Using a Multi-Dimensional Hydrogen Analysis System

Hyung Seok Kang, Jongtae Kim, Seong Wan Hong, Sang Baik Kim

Subject: Physical Sciences, Nuclear And High Energy Physics Keywords: APR1400; COM3D; Containment Integrity; Hydrogen Flame Acceleration; Multi-Dimensional Hydrogen Analysis System; Overpressure; PAR; Severe Accident

Online: 19 October 2020 (13:20:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202003.0371.v1

Knockout of MMP3 Weakened Solid Tumor Organoids and Cancer Extracellular Vesicles

Eman A. Taha, Chiharu Sogawa, Yuka Okusha, Hotaka Kawai, May Wathone Oo, Abdellatif El-Seoudi, Yanyin Lu, Hitoshi Nagatsuka, Satoshi Kubota, Ayano Satoh, Kuniaki Okamoto, Takanori Eguchi

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: matrix metalloproteinase 3 (MMP3); extracellular vesicles (EVs); tumoroid; tumor organoid; tumorigenesis; three-dimensional (3D) culture system

Online: 25 March 2020 (05:25:09 CET)

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The tumor organoid (tumoroid) model in three-dimensional (3D) culture systems has been developed to reflect more closely the in vivo tumors than 2D-cultured tumor cells. Notably, extracellular vesicles (EVs) are efficiently collectible from the culture supernatant of gel-free tumoroids. Matrix metalloproteinase (MMP) 3 is a multi-functional factor playing crucial roles in tumor progression. However, roles of MMP3 within tumor growth and EVs have not unveiled. Here, we investigated the protumorigenic roles of MMP3 on integrities of tumoroids and EVs. We generated MMP3-knockout (KO) cells using the CRISPR/Cas9 system from rapidly metastatic LuM1 tumor cells. Moreover, we established fluorescent cell lines with palmitoylation signal-fused fluorescent proteins (tdTomato and enhanced GFP). Then we confirmed the exchange of EVs between cellular populations and tumoroids. LuM1-tumoroids released large EVs (300-1000 nm) and small EVs (50-200 nm) while the knockout of MMP3 resulted in the additional release of broken EVs from tumoroids. The loss of MMP3 leads to a significant reduction in tumoroid size and to the development of the necrotic area within tumoroids. MMP3 and CD9 (a category-1 EV marker tetraspanin protein) were significantly down-regulated in MMP3-KO cells and their EV fraction. These weakened phenotypes by MMP3 KO were markedly rescued by the addition of MMP3-rich EVs or conditioned medium (CM) collected from LuM1-tumoroids, which caused a dramatic rise in the expression of MMP3, CD9, and Ki-67 (a marker of proliferating cells) in the MMP3-null/CD9-low tumoroids. Notably, MMP3 enriched in tumoroids-derived EVs and CM deeply penetrated into recipient MMP3-KO tumoroids, resulting in a remarkable enlargement of solid tumoroids, while MMP3-null EVs did not. These data demonstrate that EVs can mediate molecular transfer of MMP3 resulting in increasing the proliferation and CD9+ tumorigenesis, indicating crucial roles of MMP3 in tumor progression.

Preprint ARTICLE | doi:10.20944/preprints201809.0608.v1

Hyers-Ulam Stability of Lagrange's Mean Value Points in Two Variables

Soon-Mo Jung, Ji-Hye Kim

Subject: Computer Science And Mathematics, Analysis Keywords: Hyers-Ulam stability; mean value theorem; Lagrange's mean value point; two-dimensional Lagrange's mean value point

Online: 30 September 2018 (10:42:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201805.0109.v1

Complex Wave Solutions to Mathematical Biology Models II: Two Dimensional Fisher and Nagumo Equations

Alper Korkmaz

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: reaction-diffusion equations; two dimensional Fisher Equation; Nagumo Equation; Kolmogorov-Petrovsky-Piskunov equation; traveling wave solution

Online: 7 May 2018 (08:35:54 CEST)

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Preprint REVIEW | doi:10.20944/preprints201701.0118.v1

Peierls and Spin-Peierls Instabilities in the Per₂[M(mnt)₂] Series of One-Dimensional Organic Conductors; Experimental Realization of a 1D Kondo Lattice for M = Pd, Ni and Pt

Jean-Paul Pouget, Pascale Foury-Leylekian, Manuel Almeida

Subject: Physical Sciences, Condensed Matter Physics Keywords: organic conductors; one dimensional metal; Kondo lattice; Peierls and spin-Peierls transitions; frustrated anti-ferromagnetic systems

Online: 26 January 2017 (07:48:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints201609.0002.v1

Fractal Dimension Based Carotid Plaque Characterization from Three-Dimensional Ultrasound Images

Ran Zhou, Mingyue Ding, Yongkang Luo, Aaron Fenster

Subject: Medicine And Pharmacology, Other Keywords: fractal dimension; carotid plaque characterization; three dimensional ultrasound; an evaluation of the vulnerability of the plaques

Online: 1 September 2016 (10:48:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0655.v1

Study on the Equivalent Density Tool and Depressurization Mechanism of Suction-Type Depressurization Cycle

Meipeng Ren, Xingquan Zhang, Renjun Xie, Junyan Wang, Zhaopeng Zhu, 学彬程, Liangbin Dou

Subject: Engineering, Other Keywords: Cyclic equivalent density (ECD); Annular pressure reduction; depressurization tools; Suction-type ECD reduction tool; High temperature and high pressure

Online: 8 July 2024 (14:17:02 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202404.0833.v1

Convenient Preparation, Thermal Properties and X-Ray Structure Determination of 2,3-Dihydro-5,6,7,8-tetranitro-1,4-benzodioxine (TNBD): a Promising High Energy Density Material (HEDM)

Jonas Šarlauskas

Subject: Chemistry And Materials Science, Organic Chemistry Keywords: 1,4-benzodioxane; nitration; nitro derivatives; tetranitro; synthesis; X-ray crystallography; structure; thermal analysis; high energy high density material (HEDM)

Online: 12 April 2024 (08:03:59 CEST)

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Preprint REVIEW | doi:10.20944/preprints202104.0669.v1

The Possibility of a High-efficiency Wave Power Generation System using Dielectric Elastomers

Seiki Chiba, Mikio Waki, Changqing Jiang, Makoto Takeshita, Mitsugu Uejima, Kohei Arakawa, Kazuhiro Ohyama

Subject: Engineering, Automotive Engineering Keywords: dielectric elastomer; generation; carbon dioxide free; rare earths free; high efficiency; CNT; high power; artificial muscle; actuator; large deformation

Online: 26 April 2021 (13:09:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202101.0622.v1

Influence of Preheating Temperature on Hardness and Microstructure of PBF Steel hs6-5-3-8

Jasmin Saewe, Markus Benjamin Wilms, Lucas Jauer, Johannes Schleifenbaum

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: LPBF; Laser Powder Bed Fusion; SLM; Selective Laser Melting; High-speed steel; tool steel; high carbon content; preheating temperature

Online: 29 January 2021 (13:09:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints202410.0629.v1

Intercity Rail Fares After HSR Liberalization in Spain: The Madrid-Barcelona Corridor

Santiago García-Samaniego, Javier Campos

Subject: Economics, Business, Economics And Management Keywords: high-speed rail (HSR); rail fares; liberalization; Spain

Online: 9 October 2024 (14:39:35 CEST)

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