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Preprint COMMUNICATION | doi:10.20944/preprints201703.0034.v1

Ultrathin Six-Band Polarization-Insensitive Terahertz Perfect Metamaterial Absorber Based on a Cross-Cave Patch Resonator

Yong Zhi Cheng, Mu Lin Huang, Hao Ran Chen, Zhen Zhong Guo, Xue Song Mao, Rong Zhou Gong

Subject: Engineering, Electrical And Electronic Engineering Keywords: Planar metamaterial absorber; terahertz; six-band; cave-cross patch resonator

Online: 6 March 2017 (17:29:53 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints201703.0022.v1

Ultrathin Six-Band Polarization-Insensitive Terahertz Perfect Metamaterial Absorber Based on a Cross-Cave Patch Resonator

Yong Zhi Cheng, Mu Lin Huang, Hao Ran Chen, Zhen Zhong Guo, Xue Song Mao, Rong Zhou Gong

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: perfect metamaterial absorber; terahertz; six-band; cave-cross patch resonator

Online: 3 March 2017 (08:48:31 CET)

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Preprint ARTICLE | doi:10.20944/preprints202408.0890.v1

Identification of Natural Compounds for Long COVID Based on Hub Gene Biomarkers and Repurposed Drugs

Dinesh Davagandhi, Suresh Kumar

Subject: Biology And Life Sciences, Virology Keywords: Long COVID; Symptoms; Natural Compounds; Hub Genes; Therapeutic Drug

Online: 13 August 2024 (08:56:08 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0760.v1

Sensitivity Analysis of Airfoil Deformation for Aerial-Aquatic Navigation

Chengrong Du, Dongbiao Zhao

Subject: Engineering, Aerospace Engineering Keywords: Deformable airfoil parameterization; Aerial-aquatic airfoil; Iso-geometric method; Sobol analysis

Online: 12 August 2024 (12:34:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1051.v1

Synthesis of Quaternary Ammonium Lignin Based Ionic Liquids and Comparison of Extraction Behavior of Co(II) and Ni(II) with 2-Ethylhexyl Phosphoric Acid Mono-2-ethylhexyl Ester

Guijiang Li, Wenze Xu

Subject: Engineering, Bioengineering Keywords: quaternary ammonium lignin; ionic liquid; separation; cobalt; nickel

Online: 18 March 2024 (16:20:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints201607.0051.v1

Search for QPOs in the Light Curve of the Blazar OJ287: Preliminary Results from 2015/16 Observing Campaign

S. Zola, M. Valtonen, G. Bhatta, A. Goyal, B. Debski, A. Baran, J. Krzesinski, M. Siwak, S. Ciprini, A. Gopakumar, H. Jermak, K. Nilsson, D. Reichart, K. Matsumoto, K. Sadakane, K. Gazeas, M. Kidger, V. Piirola, F. Alicavus, K.S. Baliyan, A. Berdyugin, D. Boyd, M. Campas Torrent, F. Campos, J. Carrillo Gomez, D.B. Caton, V. Chavushyan, J. Dalessio, D. Dimitrov, M. Drozdz, A. Erdem, A. Escartin Perez, V. Fallah Ramazani, A.V. Filippenko, F. Garcia, F. Gomez Pinilla, M. Gopinathan, J.B. Haislip, J. Harmanen, G. Hurst, K.M. Ivarsen, M. Jelinek, A. Joshi, M. Kagitani, N. Kaur, N. Karaman, W.C. Keel, A.P. LaCluyze, B.C. Lee, E. Lindfors, J. Lozano De Haro, J.P. Moore, R. Naves Nogues, A.W. Neely, R.H. Nelson, W. Ogloza, S. Okano, J.C. Pandey, M. Perri, P. Pihajoki, G. Poyner, J. Provencal, T. Pursimo, A. Raj, R. Reinthal, S. Sadegi, T. Sakanoi, J.-L. Salto Gonzales, T. Schweyer, F.C. Soldan Alfaro, E. Sonbas, I. Steele, J.T. Stocke, J. Strobl, L.O. Takalo, T. Tomov, L. Tremosa Espasa, J.R. Valdes, J. Valero Perez, F. Verrecchia, J.R. Webb, M. Yoneda, M. Zejmo, W. Zheng, J. Telting, J. Saario, T. Reynolds, A. Kvammen, E. Gafton, R. Karjalainen, P. Blay

Subject: Physical Sciences, Astronomy And Astrophysics Keywords: galaxies: active; BL Lacertae objects: individual (OJ 287); super massive black holes

Online: 18 July 2016 (10:46:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0335.v1

Effect of Model Body Type and Print Angle on the Accuracy of 3D-Printed Orthodontic Models

Stefan Lohfeld, Bryndon Belnap, Jean-Marc Retrouvey, Mary P. Walker

Subject: Public Health And Healthcare, Other Keywords: digital dentistry; 3D printing; accuracy; orthodontic models; clear aligners

Online: 6 March 2024 (13:58:33 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0244.v1

The Effect of Genome Parametrization and SNP Marker Subsetting on Genomic Selection in Autotetraploid Alfalfa

Nelson Nazzicari, Nicolo Franguelli, Barbara Ferrari, Luciano Pecetti, Paolo Annicchiarico

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: legumes; alfalfa; genomic selection; SNP calling pipeline; autotetraploidy; polyploidy; genome parametrization; SNP subsetting

Online: 5 March 2024 (10:25:28 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0961.v1

Cardiac Device Therapy in Patients with Chronic Kidney Disease – an Update

Bogdan Caba, Laura Vasiliu, Alexandra Maria Covic, Radu Andy Sascau, Cristian Stătescu, Adrian C. Covic

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: CKD; HF; CRT; LVAD; ICD; CIED; CRT-D; complications; mortality

Online: 13 December 2023 (10:19:04 CET)

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Preprint REVIEW | doi:10.20944/preprints202310.0293.v1

A Systematic Review of Individualized Heart Surgery with a Personalized Prosthesis

Faizus Sazzad, KR Ramanathan, Irwan Shah Moideen, Abdulrahman El Gohary, John C Stevens, Theo Kofidis

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: personalized; individualized; open heart surgery; implantation; systematic review

Online: 5 October 2023 (13:45:08 CEST)

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Preprint REVIEW | doi:10.20944/preprints202306.1824.v1

Inhibition of Topoisomerases by Metal Thiosemicarbazone Complexes

Xiaohua Jiang, Lauren A. Fielding, Hunter Davis, William Carroll, Edward C. Lisic, Joseph E. Deweese

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: topoisomerase; thiosemicarbazone; cancer; DNA

Online: 26 June 2023 (14:18:45 CEST)

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Preprint REVIEW | doi:10.20944/preprints202208.0415.v1

Application of Magnetic Nanoparticles in Bioreactors to Enhance Mass Transfer during Syngas Fermentation

Jude A Okolie, Evelyn Sajeev, Sheshank Shekher, Kwaghtaver S Desongu, Chukwuma C Ogbaga, Burcu Gunes

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: Nanoparticles; syngas fermentation; mass transfer; biofuel; bioethanol

Online: 24 August 2022 (07:35:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202104.0605.v1

Transcriptomic Profiling of Dromedary Camels Immunised with a MERS Vaccine Candidate

Sharif Hala, Paolo Ribeca, Haya A. Aljami, Ibrahim Qasim, Sarah C. Gilbert, Naif Khalaf Alharbi

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Transcriptome; gene expression; camel; MERS-CoV; vaccine; immunogenicity

Online: 22 April 2021 (10:34:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202010.0006.v1

What Can Local Transfer Entropy Tell us About Phase-amplitude Coupling in Electrophysiological Signals?

Ramón Martínez-Cancino, Arnaud Delorme, Johanna Wagner, Kenneth Kreutz-Delgado, Roberto C. Sotero, Scott Makeig

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Phase amplitude coupling; cross frequency coupling; information theory; transfer entropy

Online: 1 October 2020 (08:59:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201807.0212.v1

Optical Pumping of TeH⁺: Implications for Search for Varying m_p/m_e

Patrick R. Stollenwerk, Mark G. Kokish, Antonio G. S. de Oliveira-Filho, Fernando R. Ornellas, Brian C. Odom

Subject: Physical Sciences, Atomic And Molecular Physics Keywords: time variation of constants; proton-electron mass ratio; molecular ion; laser cooling

Online: 12 July 2018 (08:04:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201803.0114.v1

Hydrophilic Self-Replenishing Coatings with Long-Term Water Stability for Anti-Fouling Applications

Isabel Jiménez-Pardo, Leendert G.J. van der Ven, Rolf A.T.M. van Benthem, Gijsbertus de With, A. Catarina C. Esteves

Subject: Chemistry And Materials Science, Surfaces, Coatings And Films Keywords: self-replenishing; anti-fouling; hydrophilic coatings; polycarbonate; mPEG; dangling chains

Online: 15 March 2018 (04:54:13 CET)

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Working Paper ARTICLE

Manganese Cobalt-Based Spinel Coatings Processed by Electro-Phoretic Deposition Method: The Influence of Sintering on Degadation Issues of Solid Oxide Cell Oxygen Electrodes at 750 °C

Elisa Zanchi, Justyna Ignaczak, Bartosz Kamecki, Piotr Jasinski, Sebastian Molin, Aldo R. Boccaccini, Federico Smeacetto

Subject: Chemistry And Materials Science, Biomaterials Keywords: electrophoretic deposition; manganese cobalt spinel; Solid Oxide Cell; chromium poisoning

Online: 1 June 2021 (12:00:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.1505.v1

Pepper Fruit Extracts Show Anti-Proliferative Activity against Tumor Cells Altering Their NADPH-Generating Dehydrogenase and Catalase Profiles

Marta Rodríguez-Ruiz, María C Ramos, María Jesús Campos, Inmaculada Díaz-Sánchez, Bastien Cautain, Thomas A. Mackenzie, Francisca Vicente, Francisco J. Corpas, José M Palma

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: antioxidants; capsaicin; catalase; hepatoma; hydrogen peroxide; NADPH; nitric oxide; pancreas; hot pepper

Online: 21 June 2023 (08:45:41 CEST)

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Cancer is considered nowadays one of the main causes of human death worldwide, being characterized by an alteration of the oxidative metabolism. Many natural compounds with anti-tumor attributes have been described, many of them from plant origin. Among them, capsaicin, which is the molecule responsible for the pungency in hot pepper fruits, has been reported to show antioxidant, anti-inflammatory and analgesic activities, as well as anti-proliferative properties against cancer. Thus, in this work the potential anti-proliferative activity of pepper (Capsicum annuum L.) fruits from diverse varieties with different capsaicin content (California < Piquillo < Padrón < Alegría riojana) against several tumor cell lines (lung, melanoma, hepatoma, colon, breast, pancreas, and prostate) has been investigated. The results showed that the capsaicin content in pepper fruits did not correspond with their anti-proliferative activity against tumor cell lines. By contrast, the greatest activity was promoted by the pepper tissues which contained the lowest capsaicin amount. This indicates that other compounds different from capsaicin have this anti-tumor potentiality in pepper fruits. Based on this, green fruits from the variety Alegría riojana, which has negligible capsaicin levels, was used to study the effect on the oxidative and redox metabolism of tumor cell lines from liver (Hep-G2) and pancreas (MIA PaCa-2). Different parameters from both lines treated with pepper fruit crude extracts were determined including, among others, protein nitration and protein S-nitrosation (two post-translational modifications (PTMs) promoted by nitric oxide), the antioxidant capacity, as well as the activity of the antioxidant enzymes superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPX). Besides, the activity of the NADPH-generating enzymes glucose-6-phosphate dehydrogenase (G6PDH), 6-phosphogluconate dehydrogenase (6PGDH), and NADP-isocitrate dehydrogenase (NADP-ICDH) was followed. Our data revealed that the treatment of both cell lines with pepper fruit extracts altered their antioxidant capacity, enhanced the catalase activity, and considerably reduced the activity of the NADPH-generating enzymes. As a consequence, less H2O2 and NADPH seem to be available to cells, thus avoiding cell proliferation and possibly triggering cell death in both cell lines.

Preprint ARTICLE | doi:10.20944/preprints202203.0224.v1

The Complete Mitochondrial Genome of a Neglected Breed, the Peruvian Creole Cattle (Bos taurus), and Its Phylogenetic Analysis

Carlos I. Arbizu, Rubén D. Ferro-Mauricio, Julio C. Chávez-Galarza, Héctor V. Vásquez, Jorge L. Maicelo, Carlos Poemape, Jhony Gonzales, Carlos Quilcate, Flor-Anita Corredor

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: zoogenetic resources; organelle; genomics; NGS; cattle; Bos taurus

Online: 16 March 2022 (07:36:01 CET)

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Preprint ARTICLE | doi:10.20944/preprints202408.0103.v1

Carbon Footprint Optimization with Data Resolution Conversion via Kalman Filter for Smart Energy Hub

Mohammed Mahmoud Khattab, Ahmed Abdelrahim, Eman Youssef, Mostafa Saad Hamad, Rania Elmanfaloty

Subject: Engineering, Control And Systems Engineering Keywords: Smart energy hub; carbon footprin; , dynamic pricing; Kalman filter

Online: 1 August 2024 (17:03:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1402.v1

Entire-range Cooperative Trajectory Planning of Gliding-guided Projectiles with Weak Maneuverability

Qiulin Yin, Qi Chen, Zhongyuan Wang, Qinghai Wang

Subject: Engineering, Control And Systems Engineering Keywords: gliding-guided projectile; simultaneous attack; trajectory planning; entire range; cooperation strategy; capability ranges of cooperation

Online: 23 May 2024 (11:48:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0689.v1

Robust Trajectory Planning Of Gliding-Guided Projectiles With Weak Maneuverability

Qiulin Yin, Qi Chen, Zhongyuan Wang, Qinghai Wang

Subject: Engineering, Control And Systems Engineering Keywords: gliding-guided projectile; uncertainty; robust planning; trajectory tracking guidance; closed-loop feedback

Online: 10 May 2024 (14:33:37 CEST)

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Preprint REVIEW | doi:10.20944/preprints202404.1956.v1

Biosensor-Integrated Virtual Reality (VR) System Assisted CBT and the Alteration of Delusional Perceptions in Psychosis

Aristomenis Alevizopoulos, Maria Alevizopoulou, Jacob Kritikos, Georgios Alevizopoulos

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: virtual reality (VR); biosensors; psychosis; hallucinations; delusions; cognitive behavioural treatment

Online: 30 April 2024 (07:25:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0816.v1

The Spatiotemporal Evolution of the Growing Degree Days (GDD) Agroclimatic Index for the Viticulture over the Northern Mediterranean Basin

Ioannis Charalampopoulos, Iliana Polychroni, Fotoula Droulia, Panagiotis T. Nastos

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Climate change; agroclimate; agroclimatic indices; viticulture; viticultural zoning

Online: 14 March 2024 (09:31:31 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0071.v1

Evaluation of the Ability of Using Shear-horizontal Surface Acoustic Wave Biosensors to Perform Sterility Testing of Nutrient Media

Aimofumhe Eshiobomhe Sigmus, Favour Badewole, Dy’Mond Smith, Marlon Sheldon Thomas

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Shear-horizontal Surface Acoustic Wave (SH-SAW); Biosensor; Sterility testing; Escherichia coli K-12; Phase shift

Online: 1 March 2024 (18:27:35 CET)

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Preprint REVIEW | doi:10.20944/preprints201608.0195.v1

Current Understanding on Tail Regeneration in Green Anoles (Anolis carolinensis)

Zulkar Nain, Md Ariful Islam, Sadrul Hasan Chowdhury, Sadia Afroza

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: green anole; tail autotomy; regeneration; microRNAs; Anolis carolinensis

Online: 23 August 2016 (11:25:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.0247.v1

Process Analysis and Modelling of Operators Performance in Classical and Digitalized Assembly Workstations

Georgiana Cătălina NEACŞU (DOBRIŞAN), Eduard Laurenţiu NIŢU, Ana Cornelia GAVRILUŢĂ, Georgica Gheorghiţa VLAD, Elena Mădălina DOBRE, Marian GHEORGHE, Maria Magdalena STAN

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: lean learning factory; assembly workstations; DOJO; industry 4.0; regression analysis

Online: 5 February 2024 (13:34:58 CET)

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Preprint ARTICLE | doi:10.20944/preprints202407.0197.v1

Genome-Wide Association Analysis Identifies Candidate Loci for the Callus Induction in Rice (Oryza sativa L.)

Wintai Kamolsukyeunyong, Yeetoh Dabbhadatta, Aornpilin Jaiprasert, Burin Thunnom, Wasin Poncheewin, Samart Wanchana, Vinitchan Ruanjaichon, Theerayut Toojinda, Parichart Burns

Subject: Biology And Life Sciences, Plant Sciences Keywords: Rice; GWAS; QTLs; callus induction; gene

Online: 2 July 2024 (11:10:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0034.v1

Application of Multiple geophysical Exploration Methods in the Exploration of Marine Sand Resources in the Northern Offshore Waters of the South China Sea

Gang Yu, Xichong Hu, Jie Fang, Ying Yang, Yongcong Zhang, Jinhui Lin, Jingyi Liu, Libing Qian

Subject: Environmental And Earth Sciences, Oceanography Keywords: Marine sand; Sub-bottom profile survey; Single-channel seismic survey; South China Sea

Online: 1 July 2024 (07:40:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0956.v1

Identification of SNPs in the Second Intron of IGF2BP1 and Their Association with Growth Traits in Nanjiang Yellow Goat

Shuheng Chen, Liang Xu, Junchen Len, Zitong Chen, Yu Chen, Li Li, Hongping Zhang, Mingzhou Li, Jiaxue Cao

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: IGF2BP1 gene; SNP; Association analysis; growth traits; Nanjiang yellow goat; Dual luciferase

Online: 13 June 2024 (23:52:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1599.v1

Influence of Ni Doping on Oxygen Vacancy-Induced Changes in Structural and Chemical Properties of CeO2 Nanorods

Yuanzheng Zhu, Weixia Wang, Gejunxiang Chen, Huyi Li, Yuedie Zhang, Chang Liu, Hao Wang, Ping Cheng, Chunguang Chen, Gimyeong Seong

Subject: Chemistry And Materials Science, Nanotechnology Keywords: cerium dioxide; Ni doping; oxygen vacancies; hydrothermal synthesis

Online: 26 March 2024 (12:28:56 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0814.v1

Inflammation Indexes PLR, SII, AISI, MLR, NLPR and MCVL in Peripartum Treated Thrombophilia Patients Undergoing Cesarean Section at Term-STROBE Compliant

Catalina Filip, Roxana Covali, Demetra Socolov, Ingrid Andrada Vasilache, Alexandru Carauleanu, Mona Akad, Ioana Sadyie Scripcariu, Tudor Butureanu, Gabriela Dumachita-Sargu, Lucian Vasile Boiculese, Alina Melinte, Razvan Socolov

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: thrombophilia; pregnancy; postpartum uterine ultrasonographic scale; SII; AISI; MLR; PLR; MCVL; NLPR; Rh factor

Online: 14 March 2024 (11:12:44 CET)

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Preprint ARTICLE | doi:10.20944/preprints202407.0151.v1

Evaluation of Physiological and Biochemical Reactions of Pleurotus ostreatus Cultivated in Varied Juncao Grass Substrates

Irambona Claude, Nsanzinshuti Aimable, Hatungimana Mediatrice, Lin Dongmei, Lin Zhanxi, Liu Penghu, Hengyou Zhou

Subject: Biology And Life Sciences, Life Sciences Keywords: Substrates; Pleurotus ostreatus; Biological efficiency Yield; Enzymes

Online: 2 July 2024 (08:20:37 CEST)

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Background: Pleurotus ostreutus is one of the world’s most commonly consumed mushrooms. Cultivation of mushrooms using wood resources usually results in environmental issues of deforestation. Juncao grass Pennisetum sp, Arundo Donax, and Methodology: Miscanthus are the culture mediums used in this research which offered a composting system most particularly for a simple formulation, cheap and feasible for small farms in cultivating oyster mushrooms. Results: The present study assessed the different junco grass as a substrate for growing Pleurotus ostreatus given the enzyme activities, growth, and yields. In addition, on the other hand, Lignin peroxidase (LiP) was the most active enzyme in each culture material among the other enzyme activities expressed differently between substrate and growing stages. Fruiting bodies harvested on giant grass,Arundo donax,and miscanthus,substrate weighed 159.2g/bag,132g/bag, and 65.1g/bag on average respectively. The biological efficiency of pleurotus cultivated in three different substrates was 75.2%, 63.4%, and 28.7%, respectively. Lignin peroxidase (LiP) was the most active enzyme followed by Laccase in each substrate. At the same time, other enzyme activities were differently expressed between substrate and different developmental stages. Nutrient analysis revealed significant variations, with differences in polysaccharides, proteins, and amino acids among substrates as well as the presence of heavy metals as arsenic, lead, mercury, and cadmium content in all samples was within safe limits. Conclusion: Findings from this study will serve as a solid foundation for future studies aimed at characterizing different substrate responses on enzyme activity. This research provides a sustainable footprint for subsequent research promoting eco-friendly mushroom production. The obtained results indicate that Arundo donax should be a good substrate in place of giant grass, using miscanthus is not productive based on the results obtained in this research the juncao grasses offer a sustainable approach that reduces reliance on wood-based substrates and enhances environmental sustainability.

Preprint ARTICLE | doi:10.20944/preprints202406.0380.v1

The Influence of Wildfire Climate on Wildfire Incidence: The Case of Portugal

Mário Gonzalez Pereira, Norberto Gonçalves, Malik Amraoui

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: wildfire; climate impact; spatial distribution; intra-annual variability; Portugal

Online: 7 June 2024 (02:48:12 CEST)

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Preprint REVIEW | doi:10.20944/preprints202405.1189.v1

Latest Insights into the In Vivo Studies Regarding the Role of TRP Channels in Wound Healing—A Review

Alexandra Grigore, Oana Andreia Coman, Horia Păunescu, Mihnea Costescu, Ion Fulga

Subject: Medicine And Pharmacology, Dermatology Keywords: wound healing; transient receptor potential (TRP) channels; ion channels

Online: 17 May 2024 (16:07:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1939.v1

Upregulation of Transferrin Receptor 1 (TfR1) at the Blood‐Brain Barrier by Valproic Acid, but Not of Glucose Transporter 1 (GLUT1) or CD98hc

Steinunn Sara Helgudottir, Kasper Bendix Johnsen, Lisa Greve Routhe, Charlotte LM Rasmussen, Maj Schneider Thomsen, Torben Moos

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: blood‐brain barrier; capillary depletion; CD98hc; cell culture; glucose transporter 1; ICP‐MS; nanoparticle; transferrin receptor; valproic acid

Online: 29 April 2024 (16:53:57 CEST)

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Preprint CASE REPORT | doi:10.20944/preprints202403.1623.v1

Lichen Amyloidosis in an Atopic Patient Treated with Dupilumab: A New Therapeutic Option

Benedetta Tirone, Gerardo Cazzato, Francesca Ambrogio, Caterina Foti, Marco Bellino

Subject: Medicine And Pharmacology, Dermatology Keywords: Lichen Amyloidosis; Atopic Dermatitis; Histopathology; Dupilumab

Online: 27 March 2024 (07:54:03 CET)

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Preprint ARTICLE | doi:10.20944/preprints202408.0162.v1

Effectiveness of Smartphone App for the treatment of Pediatric Obesity: A Prospective Longitudinal Study

Giuseppina Rosaria Umano, Mariapia Masino, Grazia Cirillo, Giulia Rondinelli, Francesca Massa, Giuseppe Salvatore R.C. Mangoni di Santo Stefano, Anna Di Sessa, Pierluigi Marzuillo, Emanuele Miraglia del Giudice, Pietro Buono

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: obesity 1; treatment 2; m-Health 3

Online: 2 August 2024 (12:58:08 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1835.v1

Xylella fastidiosa Dispersion on Vegetal Hosts on Demarcated Zones in the North Region of Portugal

Talita Loureiro, Luis Serra, Ângela Martins, Isabel Cortez, Patrícia Poeta

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Philaenus spumarius; olive quick decline syndrome; citrus variegated chlorosis; bacterial leaf scorch; pierce disease

Online: 28 May 2024 (12:06:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1215.v1

Evaluating the VIIRS Imagery for Developing Near Real-Time Nationwide Vegetation Cover Monitoring in Indonesia

Yudi Setiawan, Kustiyo Kustiyo, Sahid Agustian Hudjimartsu, Judin Purwanto, Riva Rovani, Anna Tosiani, Basyiruddin Usman, Tatik Kartika, Novie Indriasari, Lilik Budi Prasetyo, Belinda Arunarwati Margono

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: change detection; temporal vegetation dynamics; open area index; multi temporal VIIRS

Online: 18 April 2024 (10:57:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0371.v1

Impact Of SARS-CoV-2 Pandemic On The Diagnosis Of Cervical Cancer And Precursor Lesions - A Single Center Retrospective Study

Lavinia Balan, Cristina Secosan, Virgiliu-Bogdan Sorop, Marilena Pirtea, ANCA MARIA CIMPEAN, Daniela Chiriac, Catalin Balan, Ema Borsi, Ariana Iorga, Laurentiu Pirtea

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: covid-19; sars-cov-2; cancer diagnosis; conization; cervical cancer; colposcopy; dysplasia; biopsy

Online: 4 April 2024 (10:59:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202104.0267.v1

Drone-Based Hyperspectral and Thermal Imagery for Quantifying Upland Rice Growth and Water Use Efficiency After Biochar Application

Hongxiao Jin, Christian Josef Köppl, Benjamin M. C. Fischer, Johanna Rojas-Conejo, Mark S. Johnson, Laura Morillas, Steve W. Lyon, Ana M. Durán-Quesada, Andrea Suárez-Serrano, Stefano Manzoni, Monica Garcia

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Unmanned aerial vehicle (UAV); hyperspectral and thermal imagery; gross primary production (GPP); water use efficiency (WUE); biochar

Online: 9 April 2021 (14:46:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0144.v1

Acquisition of Social Communication Skills in Children with Autism through Applied Behavior Analysis (ABA) Parental Training and Video Modeling

Daniela Bordini, Ana Cláudia Moya, Graccielle R Cunha, Cristiane Silvestre Paula, Décio Brunoni, Helena Brentani, Sheila C Caetano, Jair de Jesus Mari, Leila Bagaiolo

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: autism spectrum disorders; applied behavior analysis; parent training; joint attention; video modelling

Online: 3 October 2023 (10:35:14 CEST)

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Preprint REVIEW | doi:10.20944/preprints202405.0353.v1

A Study on Control of Dog Food Quality, Safety and Health

Ka Man Ma, Tsz Him Chan, Shu Lun Mak, Wai Fan Tang, Wai Ying Chak, Chi Chung Lee, Chun Yin Li

Subject: Biology And Life Sciences, Life Sciences Keywords: pet foods; food safety; dog food; dry dog food; semi-moist dog food; moist dog food; regulations

Online: 7 May 2024 (10:54:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0414.v1

Triple Therapy De-escalation and Withdrawal of Inhaled Corticosteroid to Dual Bronchodilator Therapy in Patients with Chronic Obstructive Pulmonary Disease (COPD): A Systematic Review and Meta-Analysis

Edoardo Pirera, Domenico Di Raimondo, Antonino Tuttolomondo

Subject: Medicine And Pharmacology, Pulmonary And Respiratory Medicine Keywords: Chronic Obstructive Pulmonary Disease (COPD); inhaled corticosteroids (ICS); de-escalation therapy; Acute Exacerbation of COPD (AECOPD); pneumonia; eosinophils

Online: 6 September 2024 (05:51:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1521.v1

Investigation of the Interaction between Poly(trimethylene Carbonate) and Various Alcohols

Ayun Erwina Arifianti, Nalinthip Chanthaset, Hiroharu Ajiro

Subject: Engineering, Other Keywords: poly(trimethylene carbonate); interaction; alcohols; glucose

Online: 21 August 2024 (08:40:24 CEST)

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Preprint REVIEW | doi:10.20944/preprints202407.0919.v1

Ketogenic Interventions in Autosomal Dominant Polycystic Kidney Disease: A Comprehensive Review of Current Evidence

Carla Pezzuoli, Giuseppe Biagini, Riccardo Magistroni

Subject: Medicine And Pharmacology, Urology And Nephrology Keywords: ADPKD; ketogenic diet; ketosis; kidney cysts; PKD; renal function decline

Online: 11 July 2024 (04:52:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1952.v1

Responses of Soil Enzymes Activities to Sprinkler Irrigation and Differentiated Nitrogen Fertilization in Barley Cultivation

Anetta Siwik-Ziomek, Renata Kuśmierek-Tomaszewska

Subject: Environmental And Earth Sciences, Soil Science Keywords: urease; nitrate reductase; dehydrogenase; peroxidase; catalase; moderate transitory climate; soil; index of resilience

Online: 27 June 2024 (15:02:31 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1263.v1

Optimizing Traffic Flow Through Congestion Management at Peshawar Toll Plaza: A Data-Driven Approach

Adil Hussain, Muhammad Afzal, Tariq Tariq

Subject: Computer Science And Mathematics, Analysis Keywords: PTV Vissim; Toll Plaza optimization; Traffic flow; Toll-collecting effectiveness; Data analysis; Vehicle classifications; intelligent traffic management systems

Online: 20 June 2024 (10:46:17 CEST)

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Toll plaza optimization is essential for improving traffic flow and easing congestion on road networks. This study aims to suggest and assess potential optimization solutions for the Peshawar toll plaza, considering variables like traffic volume, toll-collecting effectiveness, and customer facilitation. Different resources are used for data collection, like the National Highway Authority of Pakistan. Physical data is collected from the established Toll Plaza of Peshawar, along with the development of each line. The goal of this study is to suggest and assess potential optimization solutions for the Peshawar toll plaza, considering variables like traffic volume, toll-collecting effectiveness, and customer happiness. The analysis of present traffic patterns, the detection of bottlenecks, and the creation of plans to ease congestion and enhance overall traffic flow are all part of the optimization process. The approaches used in this study include data analysis, simulation, and traffic modeling. PTV VISSIM is software for transportation planning, design, and analysis. The simulations consider various conditions, such as variable traffic volumes, toll collection methods, and lane configurations. When comparing the different optimization strategies, performance indicators like trip time, latency, and queue length are utilized to determine which approach is practical. Waiting time Vs. Existing each lane, etc, is explained. In the end, comparing queue lengths and throughput across different lane scenarios shows that maximizing throughput with existing lanes yields up to 45% improvement with E-tag lanes, 40% with existing E-tag lanes, 38% with E-tag plus additional toll and cash lanes, 32% with three cash lanes, and 28% with two E-tag lanes. Failure to regularly monitor and adjust the existing lane pattern scenario based on traffic patterns can lead to queues being 20% longer. Without proactive evaluation and optimization, there is a potential 63% opportunity for queue length improvement

Preprint ARTICLE | doi:10.20944/preprints202405.0341.v1

Analytical Modeling of Eddy Current Loss and Thermal Analysis of Non-Uniform Air Gap Combined Pole Permanent Magnet Motors for Electric Vehicles

Shilun Ma, Keqi Chen, Changwei Li, Jianwei Ma

Subject: Engineering, Electrical And Electronic Engineering Keywords: ; combined pole permanent magnet motor; non-uniform air gap; eddy-current loss; thermal analysis; equivalent thermal network ;

Online: 7 May 2024 (10:14:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1582.v1

Merits of Multi-Indicator Precautionary Approach Management in a Male-Only Crab Fishery

Darrell Mullowney, Krista Baker, Julia Pantin, William Coffey, Kyle Lefort, Katie Morrissey

Subject: Biology And Life Sciences, Aquatic Science Keywords: snow crab; Newfoundland and Labrador; fisheries management; Precautionary Approach; male-only fishery

Online: 24 April 2024 (08:31:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0054.v1

Research on Fault Detection by Flow Sequence Algorithm with Deep Learning Model for Industrial Internet of Things

Dongfeng Lei, Liang Zhao, Dengfeng Chen

Subject: Engineering, Control And Systems Engineering Keywords: Industrial Internet of Things; Deep learning; Subsequence classification; Fault diagnosis

Online: 1 March 2024 (14:05:52 CET)

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Preprint ARTICLE | doi:10.20944/preprints201702.0038.v2

Global Existence and Exponential Decay for a Dynamic Contact Problem of Thermoelastic Timoshenko Beam with Second Sound

Wenjun Liu, Dongqin Chen, Biqing Zhu

Subject: Computer Science And Mathematics, Analysis Keywords: thermoelastic Timoshenko beam; global existence; exponential stability; second sound

Online: 20 February 2017 (06:36:23 CET)

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Preprint ARTICLE | doi:10.20944/preprints201701.0096.v1

Biomineralization of Calcium and Magnesium Carbonate Minerals Induced by Bacillus licheniformis and Its Application in Water Softening

Yanyang Zhao, Hui Zhao

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: biomineralization; calcium ions; magnesium ions; Bacillus lichemiformis; carbonates

Online: 22 January 2017 (04:58:39 CET)

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Reducing the hardness of hard water is of great concern nowadays due to some adverse effects on water pipes, boilers and soap consumption. Using the method of biomineralization to precipitate calcium and magnesium ions to become carbonate minerals was one of the most important innovations for reducing the hardness of hard water. The present study sought to explore the physical and chemical conditions of carbonates bio-precipitation and the potential use of Bacillus licheniformis SRB2 strain (GenBank: KM884945.1) isolated from sludge sample of Moshui River (Shandong University of Science and Technology, Qingdao, China) in reducing the hardness of hard waters by the induction of carbonate minerals. In this study, B. licheniformis SRB2 strain was identified based on the morphological, biochemical and 16S rDNA gene sequence homology analysis. The carbonate minerals induced by B. licheniformis bacteria in the liquid culture medium with 3% NaCl and Mg/Ca molar ratio of 0, 6, 8, 10 and 12 were investigated. The culture medium was inoculated with the bacterial liquid seed was set as the experimental group and the other culture medium was inoculated with the same volume of distilled water was set as the control group. The mineral phases, micromorphologies, and crystal structures were analyzed using X-ray powder diffraction, scanning electron microscope, energy dispersive X-ray detector, high resolution transmission electron microscopy and selected area electron diffraction. The bacterial concentrations and pH values of the solution were measured by a spectrophotometer and a pH meter, respectively. The urease secreted by B. licheniformis SRB2 was found to greatly increase the pH values of the liquid medium, which favored the formation of calcium carbonate.As a result, Mg²⁺ and Ca²⁺ ion concentrations decreased greatly due to the biomineralization of calcium carbonate and nesquehonite minerals in the presence of B. licheniformis SRB2 bacterium. There were only few calcium carbonates and no nesquehonite minerals in the control groups. It was also found that the minerals of nesquehonite induced by B. licheniformis SRB2 had a phenomenon of preferred orientation. What was more, even though Mg²⁺ ions inhibited the precipitation of Ca²⁺ ions, but under the action of B. licheniformis SRB2 bacteria, the inhibition effect was significantly declined. The bio-precipitation of calcium carbonate and nesquehonite minerals may represent a new method of pretreatment for the hardness reduction of hard water. The accomplished study is of certain interest for interpretation of the carbonates biomineralization in natural environment, and maybe also has a certain application value in the former processing of hard water

Preprint ARTICLE | doi:10.20944/preprints201701.0070.v1

Performance Evaluation of a Permanent Magnet-Assisted Synchronous Reluctance Machine with Hybrid Magnets of Ferrite Magnets and Rare-earth PMs

Xiping Liu, Ya Li, Zhangqi Liu

Subject: Engineering, Electrical And Electronic Engineering Keywords: permanent magnet-assisted synchronous reluctance machine; power factor; torque ripple; efficiency; demagnetization; finite element analysis

Online: 13 January 2017 (11:04:02 CET)

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Preprint ARTICLE | doi:10.20944/preprints201608.0086.v1

Identification and Characterization of Two New Forced Degradation Products of Saikosaponin a under the Stress of Acid Hydrolytic Condition

Jun Li, Qiang Xu, Hua Jiang

Subject: Chemistry And Materials Science, Medicinal Chemistry Keywords: Acid hydrolysis; Degradation product; Saikosaponin a

Online: 9 August 2016 (11:32:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0558.v1

Long COVID: G Protein-Coupled Receptors (GPCRs) Associated Genes and Pathways as a Promising Therapeutic Potential Through Computational Analysis

Dhanyashri Guruparan, Suresh Kumar

Subject: Biology And Life Sciences, Virology Keywords: long COVID; GPCR signaling pathways; therapeutic targets; drug repurposing; bioinformatics

Online: 8 August 2024 (12:18:41 CEST)

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Long COVID, also referred to as post-COVID-19 condition, describes the lingering after-effects of COVID-19 infection. This complex syndrome encompasses a range of symptoms affecting physical well-being, cognitive function, and mental health. The widespread impact of long COVID extends beyond individual sufferers, placing significant strain on healthcare systems and causing far-reaching socioeconomic consequences. The scale of this multifaceted health crisis is unparalleled in recent history, affecting millions globally and challenging our understanding of post-viral conditions. This study aimed to explore the possibility of targeting G protein-coupled receptors (GPCRs) signaling pathway-related genes as therapeutics for long COVID using computational analysis. Targeting GPCRs and their signaling pathways holds significant promise for long COVID therapeutics, as these receptors are involved in crucial physiological processes including immune regulation, inflammation control, and neurotransmission. All of these are implicated in the diverse and persistent symptoms of long COVID, potentially offering a versatile approach to addressing multiple aspects of the condition simultaneously. This study identified 21 genes associated with GPCRs for further exploration as potential targets. Notably, GPCR genes such as HRAS, KRAS, GNAQ, and GNA11 were determined to be possible therapeutic targets for the pathophysiological mechanisms of long COVID. FDA-approved drugs targeting these genes were identified, including Binimetinib, Cabozantinib, Selumetinib, Panitumumab, Cetuximab, Adagrasib, Tipifarnib, and Sotorasib. Additionally, Naltrexone and Tipifarnib have emerged as potential new treatment options for long COVID. SARS-CoV-2 may hijack GPCR signaling pathways to dysregulate lung ion and fluid transport, contributing to the pathophysiology of pulmonary edema in patients with COVID-19. Further research is required to translate the findings into the development of therapeutics and to investigate the relationship between viral infection and GPCR signalling.

Preprint TECHNICAL NOTE | doi:10.20944/preprints202406.1272.v1

Estimation of Inferior Vena Cava Size from Ultrasound Imaging in X-Plane

Piero Policastro, Luca Mesin

Subject: Engineering, Bioengineering Keywords: Inferior vena cava; Ultrasound; Tracking

Online: 20 June 2024 (11:39:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0978.v1

Heat Conduction Control using Deep Q-Learning approach with Physics-Informed Neural Networks

N.D. Gonçalves, Jhonny de Sá Rodrigues

Subject: Engineering, Control And Systems Engineering Keywords: Physics-Informed Neural Network; Deep Q-Learning; Model Predictive Control; Heat Transfer

Online: 14 June 2024 (08:39:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0795.v1

Agent-Based Modeling for Construction Resource Positioning Using Digital Twin and BLE Technologies

Ahmed Mohammed Abdelalim, Salah Omar Said, AlJawharah A.AL Naser, Ahmed Sharaf, Adel ElSamadony, Denise-Penelope N. Kontoni, Mohamed Tantawy

Subject: Engineering, Architecture, Building And Construction Keywords: Agent-based modeling (ABM); Resource Positioning; Building Information Modelling (BIM); Digital Twin; Complex Systems; Decision Support System (DSS); Bluetooth Low Energy (BLE); Client Early Warning System (CEWS); Simulation Environment; Real-Time Monitoring

Online: 13 May 2024 (12:30:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1261.v1

Exploring the Role of Global Value Chain Position in Economic Models for Bankruptcy Forecasting

Mélanie Croquet, Loredana Cultrera, Dimitri Laroutis, Laetitia Pozniak, Guillaume Vermeylen

Subject: Business, Economics And Management, Economics Keywords: Financial econometrics; Artificial intelligence; Forecasting; GVC

Online: 16 August 2024 (17:09:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0180.v1

Biologically Active Compounds of Tomato Fruits Affected by Application of Spirulina, Dunaliella and Chlorella Microalgae Extracts

Ingrīda Augšpole, Irina Sivicka, Kaspars Kampuss, Pāvels Semjonovs, Imants Missa

Subject: Biology And Life Sciences, Food Science And Technology Keywords: microalgae; Solanum lycopersicum L; chemical composition; lycopene

Online: 2 August 2024 (11:32:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201701.0063.v1

Crystal Structure and Physical Properties of HfB4 via First-Principles Calculations

Gangtai Zhang, Rui Gao, Yaru Zhao, Tingting Bai, Yanfei Hu

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: HfB4; structure prediction; superhard material; anisotropic properties

Online: 12 January 2017 (10:57:03 CET)

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Preprint ARTICLE | doi:10.20944/preprints202409.0888.v1

Clinical, Diagnostic, and Metabolic Characteristics Associated with Nephrolithiasis in the Black Women’s Health Study

Maria J D'Amico, Richard Babayan, David Wang, Shaun Wason, Yvette C Cozier

Subject: Medicine And Pharmacology, Urology And Nephrology Keywords: nephrolithiasis; kidney stones; Black; Women; African American; metabolic evaluation

Online: 11 September 2024 (15:30:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1151.v1

Thermo-Oxidative Stability and Tribological Characteristics of Bio-Based Lubricants Synthesized Using Isoamyl Alcohol

M. Marliete F. Melo Neta, Gustavo R. R. Lima, Philipe de O. Tavares, Igor de M. Figueredo, Weslley da S. Rocha, Paulo R. C. F. Ribeiro Filho, Celio L. Cavalcante Jr., F. Murilo T. Luna

Subject: Engineering, Chemical Engineering Keywords: bio-based lubricant; thermal stability; tribology

Online: 19 September 2023 (04:08:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202302.0460.v1

Attrition Risk and Aircraft Suitability Prediction in U.S. Navy Pilot Training Using Machine Learning

Jubilee Prasad Rao, Olivia J Pinon Fisher, Jesse R Williams, Neil C Rowe, Tejas G Puranik, Dimitri N Mavris, Michael W Natali, Mitchell J Tindall, Beth W Atkinson

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Pilot Training; Machine Learning; Attrition Prediction; Aircraft Suitability; Cost Savings; Automation

Online: 27 February 2023 (08:42:14 CET)

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Preprint ARTICLE | doi:10.20944/preprints202409.0655.v1

Dose-Dependent Effects of Turmeric (Curcuma aromatica S.) Starch on Colonic Fermentation in Rats

E.M.A.C. Ekanayake, Ryota Ishii, Ryuji Nagata, Ken-ichiro Shimada, Kyu-Ho Han, Michihiro Fukushima

Subject: Biology And Life Sciences, Food Science And Technology Keywords: acetate; gut microbiota; turmeric starch; visceral fat

Online: 9 September 2024 (10:03:33 CEST)

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Preprint REVIEW | doi:10.20944/preprints202405.2105.v1

Martian Dust Storms: Reviews and Perspective for Tianwen-3 Mars Sampling Returning Mission

Fei He, Zhaojin Rong, Zhaopeng Wu, Jiawei Gao, Kai Fan, Xu Zhou, Limei Yan, Yuqi Wang, Yong Wei

Subject: Environmental And Earth Sciences, Space And Planetary Science Keywords: Mars; Dust Storm; Remote Sensing; Monitor and Forecast; Tianwen-3

Online: 31 May 2024 (08:14:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1037.v1

Design, Fabrication and Testing of a Multifrequency Microstrip RFID Tag Antenna on Si

Timothea Korfiati, Christos N. Vazouras, Christos Bolakis, Antonis Stavrinidis, Giorgos Stavrinidis, Aggeliki Arapogianni

Subject: Engineering, Electrical And Electronic Engineering Keywords: RFID Antenna; Silicon

Online: 15 May 2024 (16:54:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201610.0122.v1

Adding Agnus Castus and Magnolia to Soy Isoflavones Relieves Sleep Disturbances besides Postmenopausal Vasomotor Symptoms: Long Term Safety and Effectiveness

Pasquale De Franciscis, Flavio Grauso, Anna Luisi, Maria Teresa Schettino, Marco Torella, Nicola Colacurci

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: isoflavones; menopause management; endometrial thickness; mammary density; liver function; plant extracts

Online: 27 October 2016 (12:21:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201610.0038.v1

Research on an SVM Coupling Algorithm of Image Recognition

Ai-Min Yang, Yang Han, Jin-Ze Li, Yu-Hang Pan, Lei-Jie Shen, Yan Long, Yu-Zhu Zhang

Subject: Computer Science And Mathematics, Data Structures, Algorithms And Complexity Keywords: Face Recognition; Intelligent Coupling Algorithm; Robustnes; Accuracy; Speed

Online: 11 October 2016 (14:42:02 CEST)

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Preprint REVIEW | doi:10.20944/preprints202405.1051.v1

A Survey of Computer Vision Algorithm Applied in Driverless Robotic Vehicles with Sensing Capability

Lu Chen, Gun Li, Weisi Xie, Jie Tan, Yang Li, Junfeng Pu, Lizhu Chen, Decheng Gan, Weimin Shi

Subject: Computer Science And Mathematics, Computer Vision And Graphics Keywords: computer vision; driverless robotic vehicles; visual SLAM; deep learning; sensing capability

Online: 15 May 2024 (13:44:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.0001.v1

Heading for the Frontline: Nursing Graduates Entering the Profession During a Global Pandemic.

Victoria R. Terry, Renee L. Parsons-Smith, Jessica Elliott, Geraldine Roderick, Patricia Luyke, Peter C. Terry

Subject: Public Health And Healthcare, Nursing Keywords: Affect; coping; COVID; emotion; feeling; mood; nurse; stress

Online: 3 January 2024 (02:13:41 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0124.v1

Outpatient Embedded Palliative Care for Patients With Advanced Thoracic Malignancy: A High-Value Practice

Mary C. Boulanger, Margaret D. Krasne, Ethan K. Gough, Samantha Myers, Ilene S. Browner, Josephine L. Feliciano

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: palliative care; thoracic oncology; high-value care

Online: 4 December 2023 (03:54:29 CET)

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Preprint REVIEW | doi:10.20944/preprints202310.1911.v1

Navigating the Labyrinth: Intensive Care Challenges in Patients with Acute on Chronic Liver Failure

Fuat H. Saner, Dimitri A. Raptis, Saad Ali Alghamdi, Massimo M. Malagó, Dieter C. Broering, Dmitri Bezinover

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: cirrhosis; hemostasis disorder; ICU treatment; hemodynamic disorder; infection

Online: 30 October 2023 (11:17:47 CET)

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Preprint REVIEW | doi:10.20944/preprints202306.1727.v1

Cellular Automata Modeling as Tool in The Corrosion Management

Juan C. Reinoso-Burrows, Marcelo Cortés-Carmona, Fabiola Pineda, Mauro Henriquez, Norman Toro, Felipe M. Galleguillos Madrid

Subject: Chemistry And Materials Science, Electrochemistry Keywords: cellular automata; corrosion management; simulation corrosion; modeling corrosion

Online: 25 June 2023 (10:15:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202304.1144.v1

Antecedents of Waze Mobile Application Usage as a Solution for Sustainable Traffic Management among Gen Z

Ma. Janice J. Gumasing, Frances Jeann Charlize S. Bermejo, Keisha Taranee C. Elpedes, Lady Fatima E. Gonzales, Aaron Chastine V. Villajin

Subject: Social Sciences, Behavior Sciences Keywords: Waze Mobile Application; Technology Acceptance Model; Structural Equation Modeling

Online: 28 April 2023 (08:24:25 CEST)

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The study aims to investigate Gen Z's intentions to utilize the Waze mobile application as a solution for sustainable traffic management in Meto Manila. The extended Technology Acceptance Model (TAM) was used to define user behavior and technology usage to determine the factors influencing Filipino drivers' application acceptance of Waze. The study’s data results have revealed that the System Quality, Perceived Location Accuracy, Perceived Usefulness, and Perceived Ease of Use affect Filipinos' intentions to use traffic navigation applications, particularly Waze. The study utilized a survey and was given to 300 Filipino drivers traveling within the National Capital Region to accurately measure the factors and their connections to usage intention and actual use. The analytical approach used for this investigation was partial least squares structural equation modeling (PLS-SEM). The study's results can be applied as a theoretical framework for future researchers of Waze mobile applications, Waze route accuracy, and Waze overall application performance, as well as the features of the Waze application, to evaluate how the use of the Waze mobile application could help in the effective management of traffic situations in Metro Manila. The study was able to assess the effectiveness of the Waze navigation app as a platform for efficiently managing traffic situations in Metro Manila. Moreover, this study also highlighted the application performance of Waze and its acceptance by Filipino drivers in Metro Manila. Furthermore, the study implores a critical review of Waze's application performance. The study recommends that similar future studies must consider samples from a more diverse geographic background to obtain a more accurate representation of Filipinos traveling. Future researchers are also advised to adopt a qualitative research design to gain more detailed insights of Filipinos regarding their experience with the Waze application.

Preprint ARTICLE | doi:10.20944/preprints202304.0970.v1

Assessing the Likelihood of Failure Due to Stem Decay Using Different Assessment Techniques

Ari Okun, Nicholas J. Brazee, James R. Clark, Michael J. Cunningham-Minnick, Daniel C. Burcham, Brian Kane

Subject: Biology And Life Sciences, Forestry Keywords: tree risk assessment; decay; resistance drilling; tomography; tree risk assessment qualification; tree stem

Online: 26 April 2023 (07:41:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202302.0369.v1

Structure-Function of the Human WAC Protein in GABAergic Neurons: Towards an Understanding of Autosomal Dominant DeSanto-Shinawi Syndrome

Hannah C Rudolph, April M Stafford, Hye-Eun Hwang, Cheol-Hee Kim, Jeremy W Prokop, Daniel Vogt

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: cell biology; protein sorting; nuclear translocation; protein domain; WAC

Online: 22 February 2023 (02:37:35 CET)

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Preprint ARTICLE | doi:10.20944/preprints202302.0138.v1

Phage vs Phage: Direct Selections of Sandwich Binding Pairs

Emily C Sanders, Alicia M Santos, Eugene K Nguyen, Aidan A Gelston, Sudipta Majumdar, Gregory A Weiss

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: phage display; virus selections; sandwich binding; diagnostic assays; non-covalent binding

Online: 8 February 2023 (04:42:43 CET)

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Preprint ARTICLE | doi:10.20944/preprints202302.0104.v1

Oxidation of Aldehydes used as Food Aditives by Peroxinitrite: Organoleptic/Antoixidant Properties

Clara I Olivares, Luis García-Río, Juan C. Mejuto, Inmaculada Moreno, Francisco J Poblete, Juan Tejeda

Subject: Chemistry And Materials Science, Physical Chemistry Keywords: oxidation; aldehydes; perxoinitrite; food aditives; organoleptic properties; antioxidant properties

Online: 6 February 2023 (13:55:53 CET)

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Preprint ARTICLE | doi:10.20944/preprints202212.0110.v1

Antibiotic Stewardship in Nonoperative Management of Perforated Appendicitis: Oral Antibiotics Are an Alternative

Alvaro Eduardo Galvis, Robert Bucayu, Rebecca John, Yigit Guner MD, Antonio C. Arrieta, Delma J. Nieves

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: discharge antibiotics; complicated Appendicitis; nonoperative management; antimicrobial treatment

Online: 7 December 2022 (02:22:08 CET)

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Preprint REVIEW | doi:10.20944/preprints202204.0057.v1

Automated Coronary Optical Coherence Tomography Feature Extraction with Application to Three-Dimensional Reconstruction

Harry J. Carpenter, Mergen H. Ghayesh, Anthony C. Zander, Giuseppe Di Giovanni, Jiawen Li, Peter J. Psaltis

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: atherosclerosis; biomechanics; border detection; coronary artery disease; optical coherence to-mography; stents; vulnerable plaque

Online: 7 April 2022 (08:13:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202203.0267.v1

Bacteria-Derived Protein Aggregates Contribute to the Disruption of Host Proteostasis

Alyssa C. Walker, Rohan Bhargava, Autumn S. Dove, Amanda S. Brust, Ali A. Owji, Daniel M. Czyz

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Caenorhabditis elegans; proteostasis; bacteria; neurodegenerative diseases; protein aggregates; protein conformational disease; butyrate; aminoglycoside; Pseudomonas aeruginosa

Online: 18 March 2022 (09:21:45 CET)

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Preprint ARTICLE | doi:10.20944/preprints202201.0262.v1

Compact Midwave Imaging System: Results from an Airborne Demonstration

Michael A. Kelly, James L. Carr, Dong L. Wu, Arnold C. Goldberg, Ivan Papusha, Renee T. Meinhold

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Stereo winds; midwave infrared; weather satellite; atmospheric motion vectors

Online: 18 January 2022 (15:15:47 CET)

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The Compact Midwave Imaging System (CMIS) is a wide field of view, multi-angle, multi-spectral pushframe imager that relies on the forward motion of the satellite to create a two-dimensional (2D) image swath. An airborne demonstration of CMIS was successfully completed in January-February 2021 on the NASA Langley Research Center Gulfstream III. The primary objective of the four-flight campaign was to demonstrate the capability of this unique instrument to perform stereo observations of clouds and other particulates (e.g. smoke) in the atmosphere. It is shown that the midwave infrared (MWIR) spectral bands of CMIS provide a unique 24/7 capability with high resolution for accurate stereo sensing. The instrument relies on new focal plane array (FPA) technology, which provides excellent sensitivity at much warmer detector temperatures than traditional technologies. This capability enabled a compact, low-cost design that can provide atmospheric motion vectors and cloud heights to support requirements for atmospheric winds in the 2017-2027 Earth Science Decadal Survey. Applications include day/night observations of the planetary boundary layer, severe weather, and wildfires. A comparison with current space-based earth science instruments demonstrates that the SWIR/MWIR multi-spectral capability of CMIS is competitive with larger, more expensive instrumentation. Imagery obtained over a controlled burn and operating nuclear power plant demonstrated the sensitivity of the instrument to temperature variations. The system relies on a mature stereoscopic imaging technique applied to the same scene from two independent platforms to unambiguously retrieve atmospheric motion vectors (AMVs) with accurate height assignment. This capability has been successfully applied to geostationary and low-earth orbit satellites to achieve excellent accuracy. When applied to a ground-point validation case, the accuracy for the CMIS aircraft observations was 20 m and 0.3 m/s for cloud heights and motion vectors, respectively. This result was confirmed by a detailed error analysis with analytical and covariance models. The results for CMIS cases with underflights of Aeolus, CALIPSO and Aqua provided a good validation of expected accuracies. The paper also showed the feasibility of accommodating CMIS on CubeSats to enable multiple instruments to be flown in a leader-follower mode.

Preprint ARTICLE | doi:10.20944/preprints202111.0108.v1

Fragment-Based Virtual Screening to Discover Potential Plasmodium PI4KIIIβ Ligands

Akachukwu Ibezim, Mbanefo S. Madukaife, Sochi C Osigwe, Nadja Engel, Ramanathan Karuppasamy, Fidele Ntie-Kang

Subject: Chemistry And Materials Science, Medicinal Chemistry Keywords: Plasmodium; malaria; type III beta phosphatidylinositol 4-kinase; virtual screening; homology modeling; molecular dynamics

Online: 5 November 2021 (08:44:31 CET)

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Preprint ARTICLE | doi:10.20944/preprints202110.0416.v1

Impact of Madden - Julian Oscillation on North Indian Ocean Cyclone Intensity

M M Ali, Uppalapati Naga Tanusha, C. Purna Chand, B Himasri, Mark A. Bourassa, Y Zheng

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Madden Julian Oscillation; depressions; cyclones; machine learning

Online: 27 October 2021 (13:49:00 CEST)

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Preprint REVIEW | doi:10.20944/preprints202012.0419.v1

Immune-Checkpoint Inhibitors in B-Cell Lymphoma

Marc Armengol, Juliana C Santos, Miranda Fernández-Serrano, Núria Profitós-Pelejà, Marcelo L Ribeiro, Gaël Roué

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: immune checkpoint; lymphoid neoplasms; programmed death 1; cytotoxic T-lymphocyte antigen 4; monoclonal antibodies; combination therapies

Online: 17 December 2020 (08:10:05 CET)

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Preprint ARTICLE | doi:10.20944/preprints202007.0066.v1

NTRU-Like Random Congruential Public-Key Cryptosystem for Wireless Sensor Networks

Anas Ibrahim, Alexander Chefranov, Nagham Hamad, Yousef-Awwad Daraghmi, Ahmad Al-Khasawneh, Joel J. P. C. Rodrigues

Subject: Computer Science And Mathematics, Computer Networks And Communications Keywords: Wireless sensor network; Internet of Things; random congruential public-key cryptosystem; lattice; NTRU; polynomial; lattice basis reduction attack; LLL algorithm; Gaussian lattice reduction

Online: 5 July 2020 (11:24:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201901.0196.v2

Corticospinal Excitability to the Biceps Brachii Is not Different when Arm Cycling at a Self-Selected or Fixed Cadence

Evan J. Lockyer, Anna P. Nippard, Kaitlyn Kean, Nicole Hollohan, Duane C. Button, Kevin E. Power

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: motor evoked potential; MEP; arm cranking; pedaling; exercise

Online: 13 February 2019 (09:54:08 CET)

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Preprint ARTICLE | doi:10.20944/preprints201808.0362.v1

The Limpet: A ROS-Enabled Multi-Sensing Platform for the ORCA Hub

Mohammed E. Sayed, Markus P. Nemitz, Simona Aracri, Alistair C. McConnell, Ross M. McKenzie, Adam A. Stokes

Subject: Engineering, Electrical And Electronic Engineering Keywords: Communication Fail-Over, Fault Diagnosis, Limpet, On-board Processing, ORCA Hub, Real-time Condition Monitoring, Remote Sensing, Robots, Robot Sensing Systems, ROS Interface.

Online: 20 August 2018 (19:24:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201710.0071.v1

Elliptic Fourier Analysis in the Study of the Male Genitalia to Discriminate Three Macrolophus Species (Hemiptera: Miridae)

A. M. Jauset, E. Edo-Tena, P. M. Parés-Casanova, C. Castañé, N. Agustí, O. Alomar

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: geometric morphometrics; morphology; paramere; Macrolophus pygmaeus; Macrolophus melanotoma; Macrolophus costalis

Online: 12 October 2017 (03:31:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0594.v1

Compensatory Modulation of Seed Storage Protein Synthesis and Starch Accumulation by Selective Editing of 13 kDa Prolamin Genes in Rice

Hue Anh Pham, Kyoungwon Cho, Anh Duc Tran, Deepanwita Chandra, Jinpyo So, Hanh Thi Thuy Nguyen, Hyunkyu Sang, Jong-Yeol Lee, Oksoo Han

Subject: Biology And Life Sciences, Plant Sciences Keywords: prolamin; 13 kDa prolamin; glutelin; seed storage protein; CRISPR-Cas9; protein body; starch; rice seed; ER stress; differentially expressed genes

Online: 9 May 2024 (11:58:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202111.0212.v1

Survey of Freshly-Harvested Oat Grains from Southern Brazil Reveals High Incidence of Type B Trichothecenes and Associated Fusarium Species

Mariana Pinheiro, Caio Henrique Tadashi Iwase, Elem Caramês, BRUNO G. BERTOZZI, Lorena Carnielli-Queiroz, Nadia C. Lângaro, Eliana B. Furlong, Benedito Correa, Liliana O. Rocha

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: oats; fusarium sambucinum species complex; deoxynivalenol; nivalenol; mycotoxin

Online: 11 November 2021 (13:05:00 CET)

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Preprint ARTICLE | doi:10.20944/preprints201908.0031.v1

Aquatic Hemiptera in Southwest Cameroon: Biodiversity of Potential Reservoirs of Mycobacterium ulcerans and Multiple Wolbachia Sequence Types Revealed by Metagenomics

Seraphine N. Esemu, Xiaofeng Dong, Achah J. Kfusi, Catherine S. Hartley, Roland N. Ndip, Lucy M. Ndip, Alistair C. Darby, Rory J. Post, Benjamin L. Makepeace

Subject: Biology And Life Sciences, Insect Science Keywords: Buruli ulcer; symbiosis; Limnogonus; pond skater; riffle bug; Rhagovelia; Metrocoris; Trepobates

Online: 2 August 2019 (11:58:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1610.v1

Electroporation Delivery of Cas9 sgRNA ribonucleoprotein-Mediated Genome Editing in Sheep IVF Zygotes

Wenhui Pi, Guangyu Feng, Minghui Liu, Cunxi Nie, Cheng Chen, Jingjing Wang, Limin Wang, Pengcheng Wan, Changbin Liu, Ping Zhou, Yi Liu

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: electroporation; gene editing; CRISPR/Cas9; sheep zygotes; mutation efficiency; homologous recombination; in vitro fertilization (IVF)

Online: 19 July 2024 (12:07:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0322.v1

Enhancing Grapevine Node Detection to Support Pruning Automation: Leveraging State-of-the-Art YOLO Detection Models for 2D Image Analysis

Francisco Oliveira, Daniel Queirós da Silva, Vítor Filipe, Tatiana M. Pinho, Mário Cunha, José Boaventura Cunha, Filipe N. Santos

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: deep learning; precision agriculture; pruning; robotic systems; YOLO

Online: 4 September 2024 (08:10:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0664.v1

Socioeconomic Characteristics And Satisfaction Level Across Forest Products And Vegetable Farming Of The Agroforestry Community In Khost Province, Afghanistan

Mujib Rahman Ahmadzai, Mohd Hasmadi Ismail, Pakhriazad Hassan Zaki, Mohd. Maulana Magiman, Paiman Bawon

Subject: Biology And Life Sciences, Forestry Keywords: Agroforestry practices; socioeconomic development; natural resources; farmers; satisfaction level

Online: 9 July 2024 (13:18:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0110.v1

WebTraceSense - A Framework for the Visualization of User Log Interactions

Dennis Paulino, André Thiago Netto, Walkir A.T Brito, Hugo Paredes

Subject: Computer Science And Mathematics, Computer Science Keywords: User Log; Behavior Identification; Web Platform; DevOps; Statistical Analysis

Online: 2 August 2024 (12:27:22 CEST)

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The current surge in the deployment of web applications underscores the need to consider users' individual preferences in order to enhance their experience. In response to this, an innovative approach is emerging that focuses on the detailed analysis of interaction data captured by web browsers. This data, which includes metrics such as the number of mouse clicks, keystrokes, and navigation patterns, offers insights into user behaviour and preferences. By leveraging this information, developers can achieve a higher degree of personalization in web applications, particularly in the context of interactive elements such as online games. This paper presents the WebTraceSense project, which aims to pioneer this approach by developing a framework that encompasses a backend and frontend, advanced visualization modules, a DevOps cycle, and the integration of AI and statistical methods. The backend of this framework will be responsible for securely collecting, storing, and processing vast amounts of interaction data from various websites. The frontend will provide a user-friendly interface that allows developers to easily access and utilize the platform’s capabilities. One of the key components of this framework is the visualization modules, which will enable developers to monitor, analyse, and interpret user interactions in real-time, facilitating more informed decisions about user interface design and functionality. Furthermore, the WebTraceSense framework incorporates a DevOps cycle to ensure continuous integration and delivery, thereby promoting agile development practices and enhancing the overall efficiency of the development process. Moreover, the integration of AI methods and statistical techniques will be a cornerstone of this framework. By applying machine learning algorithms and statistical analysis, the platform will not only personalize user experiences based on historical interaction data but also infer new user behaviours and predict future preferences. In order to validate the proposed components, a case study was conducted which demonstrated the usefulness of the WebTraceSense framework in the creation of visualizations based on an existing dataset.

Preprint ARTICLE | doi:10.20944/preprints202408.0995.v1

Rationale and Protocol of ETERNITY-ITA Study: Use of Etelcalcetide for Preserving Vitamin K-Dependent Protein Activity Italian Study

Maria Fusaro, Andrea Aghi, Carmela Marino, Francesca Mallamaci, Mario Plebani, Martina Zaninotto, Maria Grano, Silvia Concetta Colucci, Maurizio Gallieni, Thomas L. Nickolas, Sandro Giannini, Stefania Sella, Paolo Simioni, Alberto Bazzocchi, Giuseppe Guglielmi, Fulvia Taddei, Enrico Schileo, Maria Carmela Versace, Giovanni Luigi Tripepi

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Bone fractures; Etecalcetide; Hemodialysis; Vascular calcification; Vitamin K.

Online: 14 August 2024 (07:14:25 CEST)

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