REVIEW
|
doi:10.20944/preprints202307.0634.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
OSCC; oral cancer; genes; mutations; miRNA; expression; mir-34a; mir-155; mir-124; mir-1; mir-16; bioinformatics; in silico analysis
Online: 11 July 2023 (04:16:04 CEST)
ARTICLE
|
doi:10.20944/preprints202305.0526.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
Colorectal cancer; mismatch repair; microsatellite instability; immune checkpoint; double negative T cells; tumor microenvironment; T-cell exhaustion; interferon-γ; PD-L1
Online: 8 May 2023 (10:53:18 CEST)
ARTICLE
|
doi:10.20944/preprints202210.0475.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
epithelial-to-mesenchymal transition (EMT); hybrid EMT; partial EMT; mesenchymal-to-epithelial transition (MET); SCAND1; SCAN zinc finger; MZF1; cancer prognosis
Online: 31 October 2022 (08:57:38 CET)
ARTICLE
|
doi:10.20944/preprints202109.0085.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
chick embryo; 3D culture; tumor models in vitro; tissue engineering; metastasis; triple-negative breast cancer; liver; mesoporous silica nanoparticles; doxorubicin; micrometastasis
Online: 6 September 2021 (11:46:54 CEST)
ARTICLE
|
doi:10.20944/preprints202103.0777.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Exosomal PD-L1 mRNA; extracellular vesicles; Triple Negative Breast Cancer; Immunotherapy; PD-L1 axis; Atezolizumab – nab-paclitaxel; Predictive biomarkers; Liquid biopsy
Online: 31 March 2021 (15:27:45 CEST)
REVIEW
|
doi:10.20944/preprints202010.0622.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Cancerous Cell, Tumors, Cancer Metastasis, Circulating Tumor Cells (CTCs), Microfluidic Devices, lab-On-a-Chip (LOC), Lab-On-a-CD (LOCD)
Online: 29 October 2020 (15:38:54 CET)
ARTICLE
|
doi:10.20944/preprints201807.0224.v2
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
pseudopterosin; triple negative breast cancer; glucocorticoid receptor alpha; dexamethasone; cell proliferation; 3D invasion; tumor spheroid; co-culture; interleukin 6; interleukin 8
Online: 2 August 2018 (06:08:31 CEST)
ARTICLE
|
doi:10.20944/preprints201806.0020.v1
Subject:
Medicine And Pharmacology,
Dermatology
Keywords:
Annona muricata; apoptosis; basal cell carcinoma; cutaneous squamous cell carcinoma; graviola; Hedgehog signaling pathway; natural products chemistry; non-melanoma skin cancer
Online: 1 June 2018 (13:00:02 CEST)
CASE REPORT
|
doi:10.20944/preprints202408.0010.v1
Subject:
Medicine And Pharmacology,
Obstetrics And Gynaecology
Keywords:
breast pathology; breast abscess; suppurative breast lesion; tuberculous mastitis; breast cancer; mastitis; idiopathic granulomatous mastitis; somatic mutations; pathogenic mutations; whole-exome sequencing
Online: 1 August 2024 (10:59:25 CEST)
ARTICLE
|
doi:10.20944/preprints202407.1031.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
18F-Fluorocholine PET/CT; radiomics; Radium-223 dichloride; castration-resistant prostate cancer with bone metastases (CRPC-BM); therapeutic failure; overall survival; nomogram.
Online: 12 July 2024 (11:18:13 CEST)
ARTICLE
|
doi:10.20944/preprints202407.0153.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Peroxisome proliferators activated receptor; inflammation; tumor suppression; non-melanoma skin cancer; actinic keratoses; cutaneous squamous cell carcinoma; transcriptomics; gene set enrichment analysis
Online: 2 July 2024 (04:09:49 CEST)
REVIEW
|
doi:10.20944/preprints202406.1292.v1
Subject:
Public Health And Healthcare,
Primary Health Care
Keywords:
Cationic lipids; cationic polymers; cationic nanostructures; Th1 improved responses; dose-dependent cytotoxicity of cationic assemblies; biocompatible polymers; combinatory approaches in cancer nanovaccines
Online: 20 June 2024 (11:47:00 CEST)
SHORT NOTE
|
doi:10.20944/preprints202404.0056.v1
Subject:
Medicine And Pharmacology,
Dermatology
Keywords:
non-melanoma skin cancer; image guided superficial radiation therapy; Mohs micrographic surgery; basal cell carcinoma; squamous cell carcinoma; superficial radiation therapy
Online: 1 April 2024 (13:32:28 CEST)
ARTICLE
|
doi:10.20944/preprints202403.1240.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
early palliative care; advanced cancer; complexity of care needs; integration of palliative care in oncology; specialist palliative care; predictive model of complexity
Online: 21 March 2024 (12:23:36 CET)
REVIEW
|
doi:10.20944/preprints202401.0676.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
HER2; breast cancer; breast neoplasms; antibody-drug conjugate; ADCs; trastuzumab emtansine; trastuzumab deruxtecan; disitamab Vedotin; ARX-788; SYD985; BL-M0701; zanidatamab zovodotin.
Online: 9 January 2024 (10:29:59 CET)
ARTICLE
|
doi:10.20944/preprints202305.0921.v2
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Stenomesson miniatum; Amaryllidaceae alkaloids; Urceolina peruviana; 13C-NMR-based dereplication; A431 human epidermoid carcinoma; skin cancer; Jurkat cells; artefact; Andean traditional medicine
Online: 14 December 2023 (12:10:15 CET)
ARTICLE
|
doi:10.20944/preprints202311.0395.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Oncotype; Recurrence Score; breast cancer; genomic risk; chemotherapy; genomic assay; Exact Sciences; Oncotype RS; Oncotype DX; clinical risk; chnages in chemotherapy; TAILORx
Online: 7 November 2023 (10:35:34 CET)
ARTICLE
|
doi:10.20944/preprints202309.0541.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
furin; cervical intraepithelial neoplasia; cervical cancer; neutrophil to lymphocyte ratio; monocyte to lymphocyte ratio; platelet to lymphocyte ratio; systemic immune-inflammatory index
Online: 8 September 2023 (03:57:19 CEST)
REVIEW
|
doi:10.20944/preprints202308.0265.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
extracellular polymeric substance (EPS); tumor microenvironment (TME); tumor microbiome (TM); tumor-associated macrophages (TAM); colorectal cancer (CRC); Fusobacterium nucleatum (Fn); Helicobacter py
Online: 3 August 2023 (10:47:22 CEST)
REVIEW
|
doi:10.20944/preprints202307.1284.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Cancer; tumourigenesis; drug resistance; signalling pathways; Wnt/β-catenin pathway; JAK/STAT pathway; PI3K/Akt/mTOR pathway; RAS/RAF/MAPK/ERK signalling
Online: 19 July 2023 (09:14:02 CEST)
COMMUNICATION
|
doi:10.20944/preprints202210.0383.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
structural biology; organelles; Golgi Apparatus (GA); Parkinson’s disease (PD); cryo-ET; alpha-synuclein; neurodegenerative diseases; soft X-ray tomography (SXT); cancer; NDDs
Online: 5 December 2022 (02:27:26 CET)
ARTICLE
|
doi:10.20944/preprints202212.0044.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
breast cancer; mastectomy; autologous breast reconstruction; PAP flap; DIEP flap; donor-site morbidity; quality of life; aesthetic outcome; scar quality; Breast Q
Online: 2 December 2022 (09:57:20 CET)
REVIEW
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
epithelial mesenchymal plasticity (EMP); epithelial mesenchymal transition (EMT); mesenchymal epithelial transition (MET); E/M Hybrid; partial EMT; computational biology; mathematical modeling; cancer
Online: 10 February 2021 (15:04:19 CET)
REVIEW
|
doi:10.20944/preprints202008.0649.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
antigen processing and presentation; cancer immunotherapy; cross-priming; immunogenicity; major histocompatibility complex; T lymphocyte; tumor-infiltrating lymphocytes, tumor microenvironment; tumor-specific antigen
Online: 30 August 2020 (10:30:50 CEST)
HYPOTHESIS
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
incurable disease; chronic disease; cancer theory; central nervous system; state memory; mutation; tissue ecosystem; emotion; stress; exercise; baseline biochemical and cellular processes
Online: 24 November 2019 (14:50:49 CET)
ARTICLE
|
doi:10.20944/preprints201906.0259.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
long non-coding RNA; cell type specific; alternative splicing; functional enrichment; RNA-binding proteins; protein binding lncRNA sponges; secondary RNA structure; cancer
Online: 26 June 2019 (05:23:29 CEST)
REVIEW
|
doi:10.20944/preprints201703.0125.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
Extracellular vesicles (EVs); Peptidylarginine deiminases (PADs); Chlor-amidine (Cl-Am); cancer; neurodegeneration; deimination; cytoskeleton; induced pluripotent stem cells (iPSCs); histone H3; epigenetics
Online: 16 March 2017 (17:54:15 CET)
ARTICLE
|
doi:10.20944/preprints202208.0345.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
Deep learning; solar radiation forecasting; model prediction; solar energy; multi climates data; generalizability; sustainability; Long Short-Term Memory (LSTM); Gated Recurrent Unit (GRU); Convolutional Neural Network (CNN); Hybrid CNN-Bidirectional LSTM; LSTM Autoencoder
Online: 18 August 2022 (10:59:18 CEST)
REVIEW
|
doi:10.20944/preprints202408.0938.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cancer immunotherapy; anti-Gal antibody; α -gal epitope; α -gal micelles; α -gal glycolipids; AGI-134; APC recruitment; α -gal therapy; tumor antigens
Online: 13 August 2024 (14:22:42 CEST)
ARTICLE
|
doi:10.20944/preprints202405.1949.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
copper requirement; cancer; PIXE; tripodal amine ligands; 64Cu2+ ion; 64Cu2+ complexes
Online: 29 May 2024 (14:16:15 CEST)
ARTICLE
|
doi:10.20944/preprints202405.0782.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Pancreatic cancer; pancreatic ductal adenocarcinoma; gemcitabine; growth hormone (GH); GH receptor (GHR); GHR antagonist; insulin-like growth factor 1 (IGF1); adjuvant; chemotherapy; chemoresistance
Online: 13 May 2024 (12:30:24 CEST)
ARTICLE
|
doi:10.20944/preprints202404.0109.v1
Subject:
Medicine And Pharmacology,
Dermatology
Keywords:
non melanoma skin cancer; basal cell carcinoma; squamous cell carcinoma; image guided superficial radiation therapy; superficial radiation therapy; image guided radiation therapy
Online: 1 April 2024 (14:58:26 CEST)
ARTICLE
|
doi:10.20944/preprints202401.0070.v2
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cancer growth; tumor metastasis; cancer's Warburg effect; p53; p53 (re)activators; mitochondrial apoptosis; cytochrome c release; tumoricidal drug effect
Online: 4 January 2024 (09:34:19 CET)
REVIEW
|
doi:10.20944/preprints202311.1426.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Complementary medicine; alternative medicine; integrative medicine; cancer care; oncology; nutritional supplements; natural products; dietary supplements; unmet needs; patient centered care; Patient doctor communication
Online: 23 November 2023 (17:26:32 CET)
ARTICLE
|
doi:10.20944/preprints202308.1485.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
breast cancer; pathologic complete response; tumour-infiltrating lymphocytes; neoadjuvant systemic therapy; CD8 antigen; forkhead box P3; programmed cell death 1 receptor; chemokine CXCL13
Online: 22 August 2023 (07:32:48 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0130.v1
Subject:
Medicine And Pharmacology,
Anesthesiology And Pain Medicine
Keywords:
Breast Cancer; Acute Postoperative Pain; Postoperative analgesia; Patient-Controlled Analgesia; Levobupivacaine; Diclofenac; Hand Grip Strength; Quality of life; Treatment Outcome; Long term survival.
Online: 2 August 2023 (04:37:34 CEST)
REVIEW
|
doi:10.20944/preprints202306.1853.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
interleukin-1 beta (IL-1β); immune-checkpoint inhibitors (ICIs); non-small cell lung cancer (NSCLC); programmed death ligand 1 (PD-L1); therapeutic resistance
Online: 27 June 2023 (07:16:09 CEST)
REVIEW
|
doi:10.20944/preprints201807.0525.v2
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
4-Hydroxynonenal; lipid peroxidation; redox balance; oxidative stress; stomach; peptic ulcer; gastritis; Helicobacter pylori; gastric cancer; non-steroid anti-inflammatory drugs-induced gastropathy
Online: 23 August 2018 (04:24:43 CEST)
ARTICLE
|
doi:10.20944/preprints202401.2034.v1
Subject:
Engineering,
Control And Systems Engineering
Keywords:
automated vehicles; connected vehicles; V2I; multi-criteria decision making (MCDM); Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS); machine learning; safety limits; cloud-based; multiple safety profiles; operational design domain(ODD)
Online: 29 January 2024 (12:25:22 CET)
CASE REPORT
|
doi:10.20944/preprints202308.1373.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
Large B-cell lymphoma (LBCL); Immunohistochemical (IHC) staining; Glucoseregulated protein 94 (GRP94); CYP3A4; Multidrug resistance protein 1 (MDR1); Aldo-keto reductase family 1 member C3 (AKR1C3); Multi-drug resistance-associated protein 1 (MRP1); P53
Online: 18 August 2023 (11:42:22 CEST)
ARTICLE
|
doi:10.20944/preprints202405.1623.v2
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
Cancer; Y2O3:Eu@SiO2 Nanoparticles; Photodynamic Therapy; Photosensitizer
Online: 23 July 2024 (09:47:03 CEST)
ARTICLE
|
doi:10.20944/preprints202407.0833.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
acylation; arginine; breast cancer; cell-penetrating peptide; histidine; MDA-MB-231; oleic acid; RNA interference; siRNA; SK-OV-3; STAT-3; tryptophan; western blotting
Online: 10 July 2024 (10:51:00 CEST)
REVIEW
|
doi:10.20944/preprints202406.0537.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
CRISPR-Cas; gene editing; gene therapy; hematology; inherited germline predisposition to cancer; bone marrow failure; acute myeloid leukemia; myelodysplastic syndromes; myeloid neoplasms; DNA repair
Online: 10 June 2024 (08:39:04 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0009.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
EGFR mutation; osimertinib; acquired resistance; secondary mutations; novel drugs; non-small cell lung cancer; epithelial to mesenchymal transition; MET gene amplification; Ba/F3 cells
Online: 4 June 2024 (02:53:41 CEST)
ARTICLE
|
doi:10.20944/preprints202404.0304.v1
Subject:
Public Health And Healthcare,
Physical Therapy, Sports Therapy And Rehabilitation
Keywords:
Multiple myeloma; Nordic Walking; intermittent fasting; sclerostin; Dickkopf-related protein 1; osteoprotegrin; Tartrate-resistant acid phosphatase 5b; Wnt pathway; vitamin D; cancer rehabilitation; elderly
Online: 3 April 2024 (14:27:03 CEST)
REVIEW
|
doi:10.20944/preprints202305.2152.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cancer metabolism; anticancer activity; artificial diets; in vivo; mice; essential amino acids; non-essential amino acids; restriction; leucine; methionine; cysteine; arginine; serine; glutamine; asparagine
Online: 30 May 2023 (13:24:11 CEST)
ARTICLE
|
doi:10.20944/preprints202202.0046.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Cancer; tumor homing peptide; in silico drug discovery; complex network; chemical space network; centrality measure; similarity searching, group fusion; motif discovery; starPep toolbox software
Online: 3 February 2022 (10:14:05 CET)
ARTICLE
|
doi:10.20944/preprints202201.0390.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
non-small cell lung cancer (NSCLC); liquid biopsy; cell-free nucleic acid (cfNA); next generation sequencing (NGS); CNA (copy number amplifications); fusions, exon-skipping.
Online: 26 January 2022 (03:21:12 CET)
ARTICLE
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
gold nanoparticles; theranostics; in vivo computed tomography imaging; non-small cell lung cancer; in vivo biodistribution; surface passivation; inductively coupled plasma optical emission spectrometry
Online: 30 December 2020 (12:28:43 CET)
ARTICLE
|
doi:10.20944/preprints202312.2063.v1
Subject:
Engineering,
Bioengineering
Keywords:
oxygen extraction faction; quantitative susceptibility mapping; quantitative blood oxygen level-dependent imaging; multi-echo complex quantitative susceptibility mapping and quantitative blood oxygen level dependent magnitude; QSM+qBOLD; QQ; mcQQ; deep learning; magnetic resonance imaging; MRI
Online: 27 December 2023 (09:10:19 CET)
ARTICLE
|
doi:10.20944/preprints202104.0020.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
hepatitis C virus; hepatocellular carcinoma; immunotherapy; multi-component DNA vaccine; nucleocapsid (core) protein; telomerase reverse transcriptase; eukaryotic expression; CD4+ and CD8+ T cell response; immune suppression; assays of reporter expression; induction of type I interferons
Online: 1 April 2021 (13:18:59 CEST)
ARTICLE
|
doi:10.20944/preprints201906.0055.v2
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
supercritical carbon dioxide; machine learning modeling; acid; artificial intelligence; solubility; artificial neural networks (ANN); adaptive neuro-fuzzy inference system (ANFIS); least-squares support-vector machine (LSSVM); multi-layer perceptron (MLP); engineering applications of artificial intelligence
Online: 31 July 2019 (04:35:26 CEST)
ARTICLE
|
doi:10.20944/preprints202404.1388.v1
Subject:
Social Sciences,
Education
Keywords:
AI impact on education; ChatGPT in exam cheating; multimodal online assessments; GPT-4 vision evaluation; educational integrity; Generative AI and examination security; large language models and assessments; critical thinking in LLMs; multi-hop reasoning in LLMs
Online: 22 April 2024 (10:29:15 CEST)
REVIEW
|
doi:10.20944/preprints202407.1569.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Cancer; tumor tissue; microwave imaging; two-photon excitation; second harmonic generation; third harmonic generation; Raman Scattering; Life-time two photon fluorescence; two-photon photodynamic therapy
Online: 19 July 2024 (10:53:17 CEST)
REVIEW
|
doi:10.20944/preprints202402.1729.v2
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
epithelial– mesenchymal transition, mesenchymal-epithelial transition, endothelial-mesenchymal transition, epithelial state, mesenchymal state, controversy, developmental biology, fibrosis, cancer, neural stemness, tumorigenicity, pluripotency
Online: 16 April 2024 (15:50:00 CEST)
ARTICLE
|
doi:10.20944/preprints202305.0276.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
fibroblast activation protein α (FAP-α); cancer-associated fibroblasts (CAFs); FAP inhibitors (FAPIs); PET imaging; gallium-68; (R)-pyrrolidin-2-yl-boronic acid-based radiopharmaceuticals
Online: 5 May 2023 (02:40:01 CEST)
ARTICLE
|
doi:10.20944/preprints201711.0193.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
computational intelligence; quantum hybrid intelligent systems; quantum machine learning; medical image processing; disease diagnosis; Fuzzy k-NN; Quantum-behaved PSO; cervical smear images; cancer detection
Online: 30 November 2017 (07:21:00 CET)
ARTICLE
|
doi:10.20944/preprints202405.1511.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Breast cancer; network pharmacology; text mining; drug therapy; genes; pathway analysis; biological process; protein-protein interaction; degree and betweenness; molecular docking; meristematic cells; anti-mitotic; hepatotoxicity
Online: 23 May 2024 (07:34:57 CEST)
ARTICLE
|
doi:10.20944/preprints202405.0092.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Nano-pulse treatment (NPT); in situ vaccination; breast cancer; tumor microenvironment; immunosuppression; apoptosis; memory T cells; regulatory T cells; myeloid-derived suppressor cells; tumor-associated macrophages
Online: 2 May 2024 (12:04:27 CEST)
REVIEW
|
doi:10.20944/preprints202307.0576.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
prostate cancer; radiation therapy; intensity-modulated radiation therapy; image-guided radiation therapy; volumetric modulated arc therapy; stereotactic body radiation therapy; brachytherapy; metastasis direct therapy; hydrogel spacer
Online: 10 July 2023 (09:43:22 CEST)
ARTICLE
|
doi:10.20944/preprints202111.0519.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
principal component analysis (PCA); motion model; respiratory-correlated four-dimensional cone-beam CT (4D-CBCT); lung cancer; stereotactic body radiotherapy (SBRT); image-guided radiation therapy (IGRT)
Online: 29 November 2021 (10:04:11 CET)
ARTICLE
|
doi:10.20944/preprints202005.0248.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
cancer; differentiation commitment; acridine-orange-DNA test; pericentromere-associated domains (PADs); power law of PAD number vs. size; critical self-organisation; unravelling of PADs; silencing threshold
Online: 15 May 2020 (08:01:08 CEST)
ARTICLE
|
doi:10.20944/preprints201711.0008.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
WNT pathway; porcupine inhibitor ETC-1922159; sensitivity analysis; colorectal cancer; unknown biological hypotheses; combinatorial search space; support vector ranking; DNA repair and genomic stability factor RAD51
Online: 1 November 2017 (05:08:04 CET)
ARTICLE
|
doi:10.20944/preprints202402.1665.v1
Subject:
Social Sciences,
Library And Information Sciences
Keywords:
Predatory research field; Science evolution; Science of Science; Social dynamics of science; Transformers; ChatGPT; BERT; Microsoft Copilot:; Large Language Model; Emerging technology; Radical Technology; Natural Language Processing Tool; AI Technology; Deep Learning Architecture; Multi-Head Attention Mechanism.
Online: 29 February 2024 (09:06:19 CET)
ARTICLE
|
doi:10.20944/preprints202310.1917.v2
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
nano-energetic materials; 2D-ordered linear-chain carbon; multi-layered nano-interfaces; self-synchronized collective atomic vibrations; phonon wave resonance; ion-assisted pulse-plasma assembling; synergistic effects; carbon nanomaterial genome approach; data-driven inverse design; energy release efficiency
Online: 29 January 2024 (04:45:42 CET)
REVIEW
|
doi:10.20944/preprints202309.1883.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
neutrophil extracellular traps (NETs); innate immunity; sepsis; lung disease; cardiovascular disease; liver disease; kidney disease; diabetes; COVID-19; coagulopathy and thrombotic microangiopathy; cancer; autoimmunity; preeclampsia; Kawasaki disease
Online: 28 September 2023 (04:00:59 CEST)
REVIEW
|
doi:10.20944/preprints202309.0633.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
metastatic hormone-sensitive prostate cancer; new hormonal agents; transcriptomic profiling; DNA damage repair genes; tumor suppressor genes; androgen receptor; immunotherapy; CDK4/6 inhibitors; PARP inhibitors; AKT inhibitors.
Online: 11 September 2023 (07:17:07 CEST)
ARTICLE
|
doi:10.20944/preprints202301.0454.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cell stress response; heat shock protein 90 (HSP90); SCAN domain-containing proteins (SCAND); MZF1; heat shock factors (HSF); co-expression correlation; Kaplan-Meyer analysis; cancer patients prognosis
Online: 25 January 2023 (10:18:20 CET)
REVIEW
|
doi:10.20944/preprints202201.0366.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cell-free DNA; liquid biopsy; cancer; next-generation sequencing (NGS); minimal residual disease; measurable residual disease; molecular residual disease (MRD); leukemia; lymphoma; myeloma; myeloproliferative neoplasms; myelodysplastic syndrome
Online: 25 January 2022 (08:13:24 CET)
REVIEW
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Neuroendocrine Neoplasms; NOTCH; cancer driven genes; mutational mechanism; germline mutations.; small cell lung carcinoma; pancreatic NET; small bowel NET; medullary thyroid carcinoma; malignant castration-resistant prostatic cells
Online: 23 July 2019 (10:34:50 CEST)
REVIEW
|
doi:10.3390/sci2030068
Subject:
Medicine And Pharmacology,
Tropical Medicine
Keywords:
COVID-19; pooling clinical trials; hyperinfection; steroids; treatment; targeted healthcare; population health management; cancer treatment; clinical research; clinical trials; developing vaccines; ranking and rating hospital quality; school closures; interventions for delirium; assessments of COVID-19 death inequities; regulatory safeguards; preventing child abuse and maltreatment; prevalence of health care worker burnout; nursing home ratings; challenging oncology practice; addressing racial; ethnic; social and economic divides; violence against sexual minority adolescents; primary tumors; metastasis; stages of cancer; reforming cancer clinical trials; supporting carers; protection and prevention; benign and malignant tumors; reforming cancer clinical trials; protection of healthcare personnel; comparing excess deaths in NYC; 1918 influenza pandemic; the possibility of full recovery from COVID-19; mental health impact of COVID-19 on young adults; ranking and rating nursing home quali
Online: 21 August 2020 (00:00:00 CEST)
REVIEW
|
doi:10.20944/preprints202401.1443.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
The Blood-Brain Barrier (BBB); CNS drug discovery; passive diffusion; active transport; Efflux transporters; Influx Transporters; P-glycoproteins (P-gp); breast cancer resistance protein (BCRP); in silico models
Online: 19 January 2024 (09:32:31 CET)
ARTICLE
|
doi:10.20944/preprints202309.0068.v1
Subject:
Medicine And Pharmacology,
Otolaryngology
Keywords:
head and neck neoplasms; head and neck cancer; head and neck squamous cell carcinoma; radiotherapy; radiochemotherapy; salvage surgery; time interval; body composition; skeletal muscle; computed tomography scan; radiomics
Online: 4 September 2023 (02:41:55 CEST)
REVIEW
|
doi:10.20944/preprints202302.0123.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
WNT; NF-κB, Ion Channels; Anthrax toxin recep- tors; Poliovirus receptors; Porcupine inhibitor ETC-1922159; Sensitivity analysis; Colorectal cancer; Unknown biological hypotheses; Combinatorial search space; Support vector ranking
Online: 7 February 2023 (06:16:12 CET)
ARTICLE
|
doi:10.20944/preprints202107.0277.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Cervical cancer; Pap smear test; whole slide image (WSI); feature pyramid network (FPN); global context aware (GCA); region based convolutional neural networks (R-CNN); Region Proposal Network (RPN).
Online: 12 July 2021 (23:05:34 CEST)
REVIEW
|
doi:10.20944/preprints202010.0510.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
disease-associated mutation; IDR; intrinsically disordered region; LLPS; phase separation; PTM; Ahr; AhRR; SIM1; SIM2; Hif-2α; NPAS4; ARNT2; BMAL1; disorder prediction; LLPS prediction; cancer; HuVarBase; catGranule prediction
Online: 26 October 2020 (10:30:47 CET)
ARTICLE
|
doi:10.20944/preprints202009.0429.v1
Subject:
Biology And Life Sciences,
Ecology, Evolution, Behavior And Systematics
Keywords:
Microplastics; Polyethylene Ocean Water; Microplastics identification; Microorganisms identification; Ocean Water quality; Drinking water; Food quality; Cancer and microplastics; plastic and ocean; particle physics; particle accelerators in environmental studies.
Online: 18 September 2020 (11:03:59 CEST)
REVIEW
Subject:
Physical Sciences,
Condensed Matter Physics
Keywords:
Si micro- and nanoparticles; optically induced dynamic nuclear polarization; optical spin orientation; nuclear spin hyperpolarization; photosensitized generation of singlet oxygen; magnetic resonance imaging; diagnostics and therapy of cancer
Online: 21 June 2020 (10:37:30 CEST)
ARTICLE
|
doi:10.20944/preprints202310.1811.v1
Subject:
Medicine And Pharmacology,
Obstetrics And Gynaecology
Keywords:
Cervical cancer; HPV screening; Prevention strategies; Human Papillomavirus; HIV interaction; "Test and Treat" approach; Number Needed to Treat; Positive Predictive Value; Negative Predictive Value; Risk management; Global health challenges
Online: 27 October 2023 (13:21:23 CEST)
REVIEW
|
doi:10.20944/preprints202306.1113.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
Inflammatory bowel disease; Colitis-associated colorectal cancer; exogenous frees hemoglobin alpha chain; Fenton reaction; DNA damage; haptoglobin; deferoxamine; flavonoids; hydrogen peroxide; hygiene; iron; nanomedicine; oxidative stress; polyphenol; pharmaceutical therapy
Online: 16 June 2023 (07:11:38 CEST)
ARTICLE
|
doi:10.20944/preprints202211.0080.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Tumor initiation; Germ cell traits of tumors; Primordial germ cell-like tumor cells; Somatic to Pri-mordial germ cell-like transformation; Embryonic/germ cell hypothesis of tumor; Breast cancer
Online: 4 November 2022 (01:04:58 CET)
ARTICLE
|
doi:10.20944/preprints202301.0086.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
diffusion-weighted whole body imaging with background suppression(DWIBS); magnetic res-onance imaging (MRI); lung cancer; response evaluation criteria in solid tumors (RECIST); ap-parent diffusion coefficient (ADC); BD Score
Online: 5 January 2023 (01:43:25 CET)
HYPOTHESIS
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
environment; virus; pollutant; evolution; exaptation; stem cells; transposons; APOBEC; ADAR,; ORF2p; cancer; Eco-Evo-Devo; symbiosis; ecological genomics; environmental stress; genetic recombination; biological plasticity; hypermutation; epigenetics; fractal systems; natural selection
Online: 19 July 2020 (19:35:46 CEST)
ARTICLE
|
doi:10.20944/preprints202405.1606.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Oral squamous cell carcinoma; OSCC; oral cancer; miRNA; miRNA expression; genes; gene expression; hyperplasia; dysplasia; early invasion; early stage OSCC; in situ carcinoma; precancerous lesions; animal model; early diagnosis; liquid biopsy
Online: 24 May 2024 (08:38:17 CEST)
REVIEW
|
doi:10.20944/preprints202311.0383.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
ACD; asymmetric cell division; AMF; amoebozoa; metazoa and fungi; DSCD; defective symmetric cell division; GRN; gene regulatory network; MGRS; multinucleated genome repair syncytium; NG; non-gametogenic germline; PGCC; polyploid giant cancer cell
Online: 7 November 2023 (11:39:43 CET)
ARTICLE
|
doi:10.20944/preprints202103.0658.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Pancreatic cancer; RNAseq; Humans; Weight loss; Prognosis; Rectus Abdominis; Carcinoma, Pancreatic Ductal; Adipose Tissue; Pancreatic Carcinoma; Pancreatic Neoplasms; Subcutaneous Fat; High-Throughput Nucleotide Sequencing; Body Composition; Muscles; Cachexia; Muscular Atrophy; Gene Expression
Online: 26 March 2021 (11:24:10 CET)
REVIEW
|
doi:10.20944/preprints202405.0500.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
Gilbert’ s syndrome (GS), Genetic variations, Protective effects of Gilbert’ s syndrome, Cancer risk, Drug interactions, Pharmacokinetic abnormalities, Clinical implications of Gilbert’ s Syndrome, Effect on NASH, Liver transplantation, Psychology and GS
Online: 9 May 2024 (02:57:19 CEST)
REVIEW
|
doi:10.20944/preprints202203.0135.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
Aspirin; COVID-19; Human blood platelets; Platelet hemostatic function; Angiogenesis; Fatty acids; Immunity; Inflammation; Non-hemostatic function; Atherosclerosis; Cancer; Diabetes; Obesity; Hypertension; Bioactive compound; Water-soluble tomato extract; Kiwi fruit; Fruitflow®; papaya leaf extract; Polyphenols; Evodiamine; Polyphenols
Online: 10 March 2022 (02:42:26 CET)
ARTICLE
|
doi:10.20944/preprints201810.0073.v1
Subject:
Medicine And Pharmacology,
Other
Keywords:
Classification; F-score; Gray-Level Co-occurrence Matrix (GLCM); Gray-Level Run-Length Matrix (GLRLM); Hepatocellular Carcinoma (HCC); Liver Cancer; Liver Abscess; Image Texture, Sequential Backward Selection (SBS); Sequential Forward Selection (SFS); Support Vector Machine (SVM); Ultrasound Image.
Online: 4 October 2018 (14:01:42 CEST)
REVIEW
|
doi:10.20944/preprints202407.1456.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
advanced therapy medicinal products (ATMPs); chimeric antigen receptors (CAR-T cells); B acute lymphoblastic leukaemia (B-ALL); food and drug administration (FDA); systemic lupus erythematosus (SLE); idiopathic inflammatory myositis (IIM); systemic sclerosis (SS); memorial sloan kettering cancer centre (MSKCC); hematopoietic stem cell transplantation [HSCT], non-Hodgkin’ s cell lymphoma (NHCL); multiple myeloma (MM); follicular lymphoma; (FL); large B cell-lymphoma (LBCL); mantle cell lymphoma (MCL); myeloid-derived suppressor cells (MDSCs); rheumatoid arthritis (RA); immune effector cell-associated neurotoxicity syndrome (ICANS); natural killer group member D ligands (NKG2DLs); acute myelogenous leukaemia (AML)
Online: 18 July 2024 (08:03:12 CEST)
ARTICLE
|
doi:10.20944/preprints202406.1554.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
Multi-Agent Systems (MAS), Machine Learning Pipelines, Supervised Learning, Data Science
Automation, Large Language Models (LLM), Reinforcement Learning (RL), Time Series Forecasting, AI Agents,
Open-Source Framework, Model Efficiency, Task Automation · Scalability in Machine Learning, Model Adaptability,
Collaborative AI Systems, Machine Learning Workflow Optimization
Automation, Large Language Models (LLM), Reinforcement Learning (RL), Time Series Forecasting, AI Agents,
Open-Source Framework, Model Efficiency, Task Automation · Scalability in Machine Learning, Model Adaptability,
Collaborative AI Systems, Machine Learning Workflow Optimization
Online: 24 June 2024 (09:50:32 CEST)
ARTICLE
|
doi:10.20944/preprints201810.0088.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
There are many molecules used as drug carrier. TUD-1 is a newly synthesized mesoporous silica (SM) molecule possess two important features; consists of mesoporous so it is very suitable to be drug carrier in addition to that it has the ability to induce apoptosis in cancer cells. However, the effect of TUD-1 appears to act as cell death inducer, regardless of whether it is necrosis or apoptosis. Unfortunately, recent studies indicate that a proportion of cells undergo necrosis rather than apoptosis, which limits the use of TUD-1 as a secure treatment. On the other hand, lithium considered as necrosis inhibitor element. Hence, current study based on the idea of production a new Li/TUD-1 by incorporated mesoporous silica (TUD-1 type) with lithium in order to produce a new compound that has the ability to activate apoptosis by mesoporous silica (TUD-1 type) and at the same time can inhibit the activity of necrosis by lithium. Herein, lithium was incorporated in TUD-1 mesoporous silica by
Online: 4 October 2018 (15:54:02 CEST)