ARTICLE
|
doi:10.20944/preprints202409.0877.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
Ligand-Receptor Binding Affinity; ziconotide; CaV2.2; Structural Biophysics; Peptide Design
Online: 11 September 2024 (10:58:35 CEST)
ARTICLE
|
doi:10.20944/preprints202404.1922.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
Insulin icodec; Binding affinity; Site-specific mutation; Receptor-mediated internalization
Online: 29 April 2024 (11:57:55 CEST)
ARTICLE
|
doi:10.20944/preprints202311.1044.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Quercetin; antiemetic; molecular docking; D2 receptor; toxicity
Online: 16 November 2023 (11:16:44 CET)
ARTICLE
|
doi:10.20944/preprints202406.1032.v1
Subject:
Medicine And Pharmacology,
Endocrinology And Metabolism
Keywords:
Semaglutide Analogues; GLP-1 Receptor Agonists; Binding Affinity Optimization; Computational Drug Design;
Online: 17 June 2024 (09:12:54 CEST)
BRIEF REPORT
|
doi:10.20944/preprints202004.0476.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
androgen insensitivity syndrome; androgen receptor; ligand binding domain; pathogenic mutation; bioinformatics
Online: 27 April 2020 (03:59:38 CEST)
ARTICLE
|
doi:10.20944/preprints202011.0363.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
cannabinoid receptor 1; synthetic cannabinoids; quantitative structure-activity relationship; multiple linear regression; partial least squares regression; dependence and abuse potential
Online: 13 November 2020 (07:19:36 CET)
ARTICLE
|
doi:10.20944/preprints201912.0374.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
alpha-fetoprotein; estrogens; selective estrogen receptor modulators; homology-based modeling; molecular docking; protein-ligand interaction; amino acid substitutions
Online: 29 December 2019 (08:08:23 CET)
ARTICLE
|
doi:10.20944/preprints202404.0469.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
Alzheimer’ s disease; amyloid β peptide; human serum albumin; low-molecular-weight ligand; protein-ligand interaction; surface plasmon resonance spectroscopy
Online: 7 April 2024 (10:18:10 CEST)
REVIEW
|
doi:10.20944/preprints202301.0099.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Atg8; autophagic receptor; Cue5; SAR; selective autophagy; selective autophagy receptor; ubiquitin; ubiquitin-binding domain; ubiquitin-binding protein; ubiquitin-binding receptor
Online: 5 January 2023 (04:33:12 CET)
REVIEW
|
doi:10.20944/preprints202404.0801.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
malaria; ligand-receptor interaction; phage display; vaccine target
Online: 11 April 2024 (11:29:14 CEST)
BRIEF REPORT
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
SARS-CoV2; spike; receptor–ligand docking; super infection
Online: 20 March 2020 (08:30:40 CET)
ARTICLE
|
doi:10.20944/preprints201902.0064.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Dopamine receptors, Molecular Docking, Molecular Dynamics, Receptor-Ligand Interactions
Online: 6 February 2019 (13:54:13 CET)
ARTICLE
|
doi:10.20944/preprints202207.0058.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
human interferon gamma; human interferon gamma receptor; receptor binding; heparan sulfate; co-receptor; molecular dynamics simulations; sodium chlorate; kynurenine antiproliferative assays; hIFNγ signalling
Online: 5 July 2022 (04:43:05 CEST)
ARTICLE
|
doi:10.20944/preprints202309.0347.v1
Subject:
Medicine And Pharmacology,
Tropical Medicine
Keywords:
Fasciola hepatica; triclabendazole; anthelmintic-resistance; amino acid-substitution; binding-pocket; ligand-protein docking; protein 3D modeling.
Online: 6 September 2023 (10:24:35 CEST)
REVIEW
|
doi:10.20944/preprints201705.0212.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
cancer; cell-surface receptor; EGFR; molecular mechanism; phosphorylation; receptor tyrosine kinase; transmembrane signal transduction
Online: 30 May 2017 (08:34:04 CEST)
ARTICLE
|
doi:10.20944/preprints201911.0071.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
NMDAR; amantadine; dansyl; fluorescent ligand; energy minima; molecular modelling; fluorescent bioassay
Online: 7 November 2019 (04:17:07 CET)
ARTICLE
|
doi:10.20944/preprints202011.0618.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Neprilisin; Docking; Molecular Dynamics Simulation; MM-PBSA; Ligand Efficiency Metrics; ADME-Tox
Online: 24 November 2020 (14:21:22 CET)
ARTICLE
|
doi:10.20944/preprints201907.0044.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Bacteriophage; Lactococcus lactis; receptor-binding protein; carbohydrate binding module; phage-host interactions
Online: 2 July 2019 (11:45:19 CEST)
ARTICLE
|
doi:10.20944/preprints201910.0281.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
protein structural dynamics; NQO1; ligand binding; protein stability; allostery; protein degradation
Online: 24 October 2019 (15:41:46 CEST)
ARTICLE
|
doi:10.20944/preprints202402.0093.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
SARS-CoV-2; variants; spike glycoprotein; receptor binding motif; receptor binding domain; neutralizing antibodies; Ig subclasses; IgG; IgA
Online: 2 February 2024 (07:31:35 CET)
ARTICLE
|
doi:10.20944/preprints202311.0296.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
SARS-CoV-2; Variants; Spike Glycoprotein; Receptor Binding Motif, Receptor Binding Domain; Neutralizing Antibodies; Ig subclasses; IgG; IgA
Online: 7 November 2023 (11:27:48 CET)
ARTICLE
|
doi:10.20944/preprints202407.2074.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
TNF-related apoptosis-inducing ligand; Eugenol; death receptor; endoplasmic reticulum stress; ROS; siRNA
Online: 26 July 2024 (04:27:29 CEST)
ARTICLE
|
doi:10.20944/preprints201901.0062.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
small molecule; ligand; receptor; docking; molecular dynamics; DNA repair; inhibition; PCNA; ADME; toxicology
Online: 8 January 2019 (11:10:26 CET)
REVIEW
|
doi:10.20944/preprints202308.0821.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
ligand-free receptor signaling; inverse agonist; neutral antagonist; μ opioid receptor; opioid dependence; 6β-naltrexol; psychedelics; LSD; 5-HT2A; GHSR
Online: 10 August 2023 (09:48:03 CEST)
ARTICLE
|
doi:10.20944/preprints202102.0318.v3
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Machine Learning; Artificial Intelligence; Androgen Receptor; Random Forest; Deep Neural Network; Convolutional
Online: 24 February 2021 (13:14:01 CET)
ARTICLE
|
doi:10.20944/preprints202310.1074.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
mixed-based combinatorial library; structure–activity relationships; cyclic peptide; mu-opioid receptor; delta-opioid receptor; bifunctional ligand; antinociception; opioid antagonist; opioid liabilities
Online: 17 October 2023 (11:21:32 CEST)
ARTICLE
|
doi:10.20944/preprints202407.0549.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
single-molecule FRET; single-molecule microscopy; receptor-ligand interaction; T cell receptor; bond lifetime quantification; T cell activation; antigen sensitivity; simulation; survival analysis
Online: 9 July 2024 (03:56:29 CEST)
REVIEW
|
doi:10.20944/preprints202009.0420.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
COVID-19; SARS-CoV-2; ACE2 receptor; spike glycoprotein; S glycoprotein immunogenic sequences; ACE2 polymorphism
Online: 18 September 2020 (04:56:02 CEST)
ARTICLE
|
doi:10.20944/preprints202211.0482.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Biothermodynamics of viruses; HIV-1; Binding constant; Gibbs energy of binding; Antigen-receptor binding
Online: 25 November 2022 (12:44:38 CET)
ARTICLE
|
doi:10.20944/preprints202312.1205.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
idiopathic pulmonary fibrosis; fibrogenesis; chemokine receptor; ligand-induced internalization; co-immunoprecipitation; collagen; alpha-smooth muscle actin; FGF2
Online: 15 December 2023 (16:01:32 CET)
ARTICLE
|
doi:10.20944/preprints202211.0031.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
GPCRs; Kappa opioid receptor; Salvinorin A; Natural products; docking; molecular dynamics simulations; dynophores
Online: 1 November 2022 (14:20:16 CET)
ARTICLE
|
doi:10.20944/preprints202311.0981.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Bacteriophage; Genome sequence; Diversity-generating retroelement; C-type lectin; Tentaclin; Adhesin; Ig-like domain; Receptor-binding protein
Online: 15 November 2023 (09:55:37 CET)
ARTICLE
|
doi:10.20944/preprints201908.0182.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
indirubin-3′-monoxime; p53; death receptor 5; TNF-related apoptosis-inducing ligand; transcription factor C/EBP homologous protein
Online: 17 August 2019 (04:19:38 CEST)
BRIEF REPORT
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
heterologous vaccine; receptor-binding domain; subunit vaccine; coronavirus; COVID-19; SARS; SARS-CoV-2
Online: 4 March 2020 (05:19:16 CET)
ARTICLE
|
doi:10.20944/preprints202312.0794.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
co-delivery; silica nanoparticles; vaccine adjuvant; toll-like receptor 7/8 (TLR7/8) ligand; INI-4001; influenza virus; hemagglutinin H7
Online: 12 December 2023 (05:25:44 CET)
REVIEW
|
doi:10.20944/preprints201811.0409.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
G quadruplex, Oncogene, ligand, cancer
Online: 16 November 2018 (11:34:24 CET)
ARTICLE
|
doi:10.20944/preprints201808.0298.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Heterodimeric G protein coupled receptor; saturation transfer difference nuclear magnetic resonance spectroscopy; differential scanning calorimetry; circular dichroism; intrinsic fluorescence spectroscopy
Online: 17 August 2018 (11:15:39 CEST)
ARTICLE
|
doi:10.20944/preprints202003.0296.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
retinol binding protein 4 receptor 2; RBP4; Rbpr2; STRA6; all-trans retinol transport; photoreceptor cell; vision; retinoids; zebrafish
Online: 19 March 2020 (03:16:19 CET)
ARTICLE
|
doi:10.20944/preprints202308.1603.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Multiplicity of infection; cell density at infection; SARS-CoV-2; Spike S1 glycoprotein; Receptor binding domain; Sf9 cells
Online: 23 August 2023 (07:53:03 CEST)
ARTICLE
|
doi:10.20944/preprints202310.1322.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Drynaria fortunei-derived polysaccharides; bone marrow-derived macrophages; osteoclastogenesis; receptor activator of nuclear factor-κB ligand; nuclear factor of activated T cells 1
Online: 20 October 2023 (12:08:32 CEST)
ARTICLE
|
doi:10.20944/preprints202402.0260.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Estrogen Receptor; Progestrone Receptor; Human epidermal growth factor Receptor
Online: 5 February 2024 (15:21:45 CET)
REVIEW
|
doi:10.20944/preprints202308.0434.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
In silico studies; drug discovery; SARS-CoV-2; molecular docking; virtual screening; molecular dynamics simulations; drug candidates; antiviral activity; receptor-ligand complex; drug design
Online: 4 August 2023 (11:11:21 CEST)
ARTICLE
|
doi:10.20944/preprints202311.1953.v1
Subject:
Chemistry And Materials Science,
Organic Chemistry
Keywords:
palladium-catalyzed; 2-pyridone ligand; tertiary aldehydes
Online: 30 November 2023 (05:45:42 CET)
ARTICLE
|
doi:10.20944/preprints202309.1323.v1
Subject:
Chemistry And Materials Science,
Inorganic And Nuclear Chemistry
Keywords:
dual emission; ruthenium; polypyridyl ligand; electrochemistry; photophysics
Online: 19 September 2023 (13:28:20 CEST)
ARTICLE
|
doi:10.20944/preprints201902.0124.v4
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
enzymes Cyclooxygenase, ligand, metabolites, antiinflammatory, Molecular Docking
Online: 29 May 2019 (11:39:02 CEST)
ARTICLE
|
doi:10.20944/preprints202111.0396.v1
Subject:
Biology And Life Sciences,
Ecology, Evolution, Behavior And Systematics
Keywords:
Progesterone Receptor; Mineralocorticoid Receptor; Evolution; Zebrafish
Online: 22 November 2021 (13:52:50 CET)
REVIEW
|
doi:10.20944/preprints202407.1052.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Prostate cancer; nuclear hormone receptors; androgen receptor; thyroid hormone receptor; retinoic acid receptor; vitamin D receptor
Online: 12 July 2024 (13:59:33 CEST)
ARTICLE
|
doi:10.20944/preprints202403.0398.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
immune escape; tumor immunity; immune checkpoint; oral squamous cell carcinoma; programmed death receptor-1 (PD-1); programmed cell death 1-ligand 1 (PD-L1); CD47
Online: 7 March 2024 (07:49:57 CET)
ARTICLE
|
doi:10.20944/preprints202405.0060.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
Enthalpy-Entropy compensation; Protein Ligand Interactions; Thermodynamic Parameters
Online: 1 May 2024 (07:45:22 CEST)
ARTICLE
|
doi:10.20944/preprints202107.0295.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
SARS-CoV-2 spike protein; ACE2 host receptor; nanobodies; molecular dynamics; mutational sensitivity; binding free energy; allosteric interactions; signal transmission
Online: 13 July 2021 (11:18:02 CEST)
REVIEW
|
doi:10.20944/preprints202302.0009.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
G-protein-coupled receptor; allosteric site; allosteric modulator; pepducin; heterotrimeric G-protein; autoantibody; thyroid-stimulating hormone receptor; luteinizing hormone receptor; proteinase-activated receptor; chemokine receptor
Online: 1 February 2023 (10:54:07 CET)
ARTICLE
|
doi:10.20944/preprints202401.1836.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Malaria; Virtual Screening; Molecular Dynamics Simulation; Pharmacophore; Modelling; Ligand
Online: 25 January 2024 (14:26:11 CET)
ARTICLE
|
doi:10.20944/preprints202104.0245.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
bis(tetrazine); coordination; host-guest; ligand; silver; XRD structure
Online: 8 April 2021 (14:27:58 CEST)
REVIEW
|
doi:10.20944/preprints201810.0312.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
upconversion; nanoparticles; lanthanide; surface modification; functionalisation; ligand engineering; silanisation;
Online: 15 October 2018 (12:59:30 CEST)
ARTICLE
|
doi:10.20944/preprints202110.0304.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
1,25-dihydroxyvitamin D; vitamin D receptor; vitamin D receptor; fibroblast growth factor receptor; signal transduction; differentiation
Online: 21 October 2021 (10:52:39 CEST)
ARTICLE
|
doi:10.20944/preprints202405.1197.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
melatonin receptor; androgen receptor; oxidative stress; male infertility; antioxidant enzyme
Online: 17 May 2024 (16:01:10 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0087.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
G-Protein Coupled Receptors; beta-3-adrenergic receptor; receptor desensitization
Online: 6 May 2021 (13:16:27 CEST)
ARTICLE
|
doi:10.20944/preprints201705.0126.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
amyloid peptides; androgen receptor; nuclear receptor; aggregation; atomic force microscopy
Online: 16 May 2017 (17:48:54 CEST)
REVIEW
|
doi:10.20944/preprints202407.1270.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
Enterovirus; Multi-target directed ligand; Clinical Trials; Combination; Drug design
Online: 16 July 2024 (08:27:11 CEST)
ARTICLE
|
doi:10.20944/preprints202401.0084.v1
Subject:
Chemistry And Materials Science,
Inorganic And Nuclear Chemistry
Keywords:
lanthanide oxygen cluster; magnetocaloric effect; magnetic refrigerant materials; rhodamine ligand
Online: 3 January 2024 (02:15:52 CET)
ARTICLE
|
doi:10.20944/preprints202305.1903.v1
Subject:
Chemistry And Materials Science,
Theoretical Chemistry
Keywords:
Analysis of magnetic shieldings; electronic mechanisms; LRESC-Loc; Ligand-dependent
Online: 26 May 2023 (09:41:54 CEST)
REVIEW
|
doi:10.20944/preprints202302.0510.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Metal-Based Drugs; CuZn; Anti-Chemoresistance; Osteosarcoma Therapy; Ligand Biosensors.
Online: 28 February 2023 (06:51:00 CET)
ARTICLE
|
doi:10.20944/preprints202401.1072.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
antidepressant; BDNF; mGlu5 receptor; M-5MPEP; RAAD; (R)-ketamine; TrkB receptor
Online: 15 January 2024 (08:30:44 CET)
REVIEW
|
doi:10.20944/preprints202305.1010.v2
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
kallikrein-kinin system; kininogens; bradykinin; B1 receptor; B2 receptor; hereditary angioedema
Online: 6 June 2023 (09:42:29 CEST)
ARTICLE
|
doi:10.20944/preprints202304.0280.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
Androgen receptor; androgen receptor splice variant 7; prostate cancer; localization; NanoBiT
Online: 13 April 2023 (02:54:24 CEST)
ARTICLE
|
doi:10.20944/preprints202209.0198.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Cholecystokinin-2 receptor; minigastrin; peptide receptor radionuclide therapy; lutetium-177, theranostics
Online: 14 September 2022 (08:39:42 CEST)
ARTICLE
|
doi:10.20944/preprints201903.0001.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
shark steroids; steroid receptor evolution; mineralocorticoid receptor evolution; progesterone; aldosterone; cortisol
Online: 1 March 2019 (06:37:37 CET)
ARTICLE
|
doi:10.20944/preprints202404.1891.v1
Subject:
Chemistry And Materials Science,
Inorganic And Nuclear Chemistry
Keywords:
single-molecular nanomedicine; porphyrin ligand; chemodynamic therapy; ferroptosis; breast cancer therapy
Online: 29 April 2024 (09:55:51 CEST)
REVIEW
|
doi:10.20944/preprints202207.0180.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
plasma membrane; membrane domains; nanodomains; neurotransmitter receptors; cannabinoids; acetylcholine receptor; cannabinoid receptor.
Online: 12 July 2022 (09:17:01 CEST)
ARTICLE
|
doi:10.20944/preprints202012.0513.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
apoferritin nanocarriers; controlled drug delivery; idarubicin; ferritin receptor targeting; folate receptor targeting
Online: 21 December 2020 (11:28:08 CET)
REVIEW
|
doi:10.20944/preprints202309.1647.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
macrophage; inflammation; acetylcholine receptor; cholinergic receptor; polarization, cholinergic agonist; alpha 7 nicotinic acetylcholine receptor; CHRFAM7A, cholinergic machinery, cholinergic anti-inflammatory pathway
Online: 25 September 2023 (09:28:51 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0525.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
COVID-19; glycyrrhizin; mineralocorticoid receptor; toll like receptor 4; angiotensin converting enzyme; aldosterone
Online: 21 May 2021 (15:11:30 CEST)
ARTICLE
|
doi:10.20944/preprints201901.0320.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Acanthamoeba sp.; eyes; toll-like receptor 2 (TLR2); toll-like receptor 4 (TLR4)
Online: 31 January 2019 (07:00:38 CET)
ARTICLE
|
doi:10.20944/preprints201610.0027.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Liver X receptor (LXR); Peroxisome proliferator-activated receptor (PPARγ); Adipose expansion; Insulin resistance
Online: 10 October 2016 (07:56:30 CEST)
ARTICLE
|
doi:10.20944/preprints202408.1826.v1
Subject:
Chemistry And Materials Science,
Polymers And Plastics
Keywords:
titanium; catalyst; homogeneous catalyst; copolymerization; half-titanocene; ethylene; styrene; ligand effect; cyclopentadienyl
Online: 26 August 2024 (11:30:09 CEST)
REVIEW
|
doi:10.20944/preprints202406.1388.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
acute myeloid leukemia; NPM1 mutation; immunogenic subtype; Programmed Death Ligand 1; immunotherapy
Online: 20 June 2024 (08:30:47 CEST)
ARTICLE
|
doi:10.20944/preprints202401.1778.v1
Subject:
Chemistry And Materials Science,
Organic Chemistry
Keywords:
Rhodium; tridentate ligand; tandem reaction; allylic decarboxylation; cycloaddition; C−N Bond Formation
Online: 25 January 2024 (05:18:35 CET)
ARTICLE
|
doi:10.20944/preprints202309.1826.v1
Subject:
Chemistry And Materials Science,
Inorganic And Nuclear Chemistry
Keywords:
coordination polymers; coordination networks; triazole ligand; iron(II); self-assembly; hydrogen bonds
Online: 27 September 2023 (07:17:13 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1131.v1
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
adipokine; chemokine (C-C motif) ligand 2; interleukin-6; leptin; neonatal; preeclampsia
Online: 16 May 2023 (09:00:30 CEST)
ARTICLE
|
doi:10.20944/preprints202303.0082.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
CENPA; cell cycle; pan-cancer; diagnostic; prognostic; glioma; immune; protein-ligand docking
Online: 6 March 2023 (02:38:13 CET)
REVIEW
|
doi:10.20944/preprints202211.0484.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
G-quadruplex DNA; G4-ligand; class switch recombination; transcriptional regulation; B lymphocytes
Online: 28 November 2022 (01:20:40 CET)
ARTICLE
|
doi:10.20944/preprints202204.0053.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Programmed death ligand-1; Natural products; Immunotherapy; Neoenactin B1; Molecular dynamics simulation
Online: 7 April 2022 (04:08:19 CEST)
REVIEW
|
doi:10.20944/preprints202003.0285.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
HIF-1α; NQO1; hypoxia; angiogenesis; cancer; protein:protein interactions; ligand binding; proteasomal degradation
Online: 18 March 2020 (08:45:33 CET)
REVIEW
|
doi:10.20944/preprints201608.0054.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
influenza virus; antiviral agent; proteomics; phosphoproteomics; metabolomics; transcriptomics; genomics; virtual ligand screening
Online: 5 August 2016 (12:41:07 CEST)
ARTICLE
|
doi:10.20944/preprints202009.0374.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
aldosterone; apoptosis; cardiac myocyte; eplerenone; fibrosis; finerenone; G protein-coupled receptor kinase (GRK)-5; mineralocorticoid receptor; mineralocorticoid receptor antagonist (MRA); signal transduction
Online: 17 September 2020 (05:24:29 CEST)
REVIEW
|
doi:10.20944/preprints202310.0928.v1
Subject:
Chemistry And Materials Science,
Organic Chemistry
Keywords:
naphtoquinones; Parkinson disease; P2X7 receptor
Online: 16 October 2023 (08:43:32 CEST)
REVIEW
|
doi:10.20944/preprints202306.2241.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
glucocorticoid receptor; reproduction; pregnancy; stress
Online: 4 July 2023 (03:29:11 CEST)
REVIEW
|
doi:10.20944/preprints202305.1558.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Melanocortin; receptor; peptide; modulator; disease
Online: 23 May 2023 (04:16:14 CEST)
ARTICLE
|
doi:10.20944/preprints202107.0665.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
cannabinoid receptor; inflammation; astrocytes; immunohistochemistry
Online: 29 July 2021 (14:11:55 CEST)
ARTICLE
|
doi:10.20944/preprints202002.0194.v1
Online: 14 February 2020 (10:52:21 CET)
ARTICLE
|
doi:10.20944/preprints202401.1876.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
nuclear hormone receptor, agonist, bile acid receptor, FXR, TGR5, triple-negative breast cancer, TNBC
Online: 26 January 2024 (11:49:34 CET)
REVIEW
|
doi:10.20944/preprints202307.0175.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
CGRP; PACAP; VIP; adrenomedullin; amylin; KATP receptor; BKCa receptor; purinergic pathway; TRP channels; Glutammate
Online: 4 July 2023 (09:52:42 CEST)
ARTICLE
|
doi:10.20944/preprints202406.1413.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
Acute lymphoblastic leukemia; RANK Ligand; Osteoprotegerin; 25(OH)D; Corticosteroids; Bone turnover markers
Online: 20 June 2024 (09:40:20 CEST)
ARTICLE
|
doi:10.20944/preprints202304.1114.v1
Subject:
Chemistry And Materials Science,
Inorganic And Nuclear Chemistry
Keywords:
C,N-chelate ligand; o-carborane; organoaluminum complexes; X-ray crystallography; intramolecular stabilization
Online: 28 April 2023 (04:50:36 CEST)
ARTICLE
|
doi:10.20944/preprints202303.0502.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Tuberculosis; Biscoumarins; Ligand molecules; DprE1; Anti-tuberculosis activity; Molecular docking; MD Simulation; Cytotoxicity
Online: 29 March 2023 (04:21:45 CEST)
ARTICLE
|
doi:10.20944/preprints202011.0292.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Alzheimer's disease; BACE1; Molecular dynamics; MM/GBSA; Inhibitors; Drug likeness; Ligand efficiency, Kd.
Online: 10 November 2020 (09:10:50 CET)
ARTICLE
|
doi:10.20944/preprints201805.0380.v1
Subject:
Chemistry And Materials Science,
Theoretical Chemistry
Keywords:
molecular dynamics simulation; biophenols; natural compounds; amyloid fibrils; Alzheimer’s disease; ligand-protofiber interactions
Online: 27 May 2018 (13:09:22 CEST)
ARTICLE
|
doi:10.20944/preprints202409.0493.v1
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
estrogen receptor; immune organ; pregnancy; sheep
Online: 9 September 2024 (02:54:54 CEST)
ARTICLE
|
doi:10.20944/preprints202408.0174.v1
Subject:
Chemistry And Materials Science,
Organic Chemistry
Keywords:
Calix[4]arene; Conformations; Receptor; Bifunctional
Online: 2 August 2024 (11:54:01 CEST)
ARTICLE
|
doi:10.20944/preprints202407.0335.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
α1β2γ2 GABAA receptor; pentameric structure; homopentamers
Online: 3 July 2024 (11:37:30 CEST)