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Preprint ARTICLE | doi:10.20944/preprints202407.0377.v1

Revealing the Hidden Impacts: Insights into Biological Aging and Long-Term Effects in Pauci- and Asymptomatic COVID-19 Healthcare Workers

Manuela Campisi, Luana Cannella, Anna Bordin, Paola Mason, Angelo Moretto, Maria Luisa Scapellato, Filippo Liviero, Sofia Pavanello

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: Biological aging; DNA methylation age; Telomere length; post COVID-19; Healthcare workers; Pauci-symptomatic; Heart Rate Variability; Nasal cells; Induced sputum.

Online: 4 July 2024 (09:18:47 CEST)

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Preprint REVIEW | doi:10.20944/preprints202407.0173.v1

Enhancement of orthodontic tooth movement by local administration of biofunctional molecules: a comprehensive systematic review

Cristina Dora Ciobotaru, Dana Feștilă, Elena Dinte, Alexandrina Muntean, Bianca Adina Boșca, Anca Ionel, Aranka Ilea

Subject: Medicine And Pharmacology, Dentistry And Oral Surgery Keywords: orthodontic tooth movement; tooth movement acceleration; biomolecules; drugs; local administration; topical formulation

Online: 2 July 2024 (09:45:44 CEST)

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Enhancement of orthodontic tooth movement (OTM) through local administration of biofunctional molecules has become increasingly significant, particularly for adult patients seeking aesthetic and functional improvements. This comprehensive systematic review analyzes the efficacy of various biofunctional molecules in modulating OTM, focusing on the method of administration and its feasibility, especially considering the potential for topical application. A search across multiple databases yielded 36 original articles of experimental human and animal OTM models, which examined biofunctional molecules capable of interfering with the biochemical reactions that cause tooth movement during orthodontic therapy, accelerating the OTM rate through their influence on the bone metabolism (Calcitriol, Prostaglandins, Recombinant human Relaxin, RANKL and RANKL expression plasmid, growth factors, PTH, osteocalcin, vitamin C and E, biocompatible reduced graphene oxide, exogenous thyroxine, sclerostin protein, a specific EP4 agonist (ONO-AE1-329), carrageenan and herbal extracts). The results indicated a variable efficacy in accelerating OTM, with Calcitriol, Prostaglandins (PGE1 and PGE2), RANKL, growth factors and PTH, among others, showing promising outcomes. PGE1, PGE2 and Calcitriol experiments had statistically significant outcomes in both human and animal studies, and, while other molecules underwent only animal testing, they could be validated in the future for human use. Notably, only one of the animal studies explored topical administration, which also suggests a future research direction. This review concluded that while certain biofunctional molecules demonstrated potential for OTM enhancement, the evidence is not definitive. The development of suitable topical formulations for human use could offer a patient-friendly alternative to injections, emphasizing comfort and cost-effectiveness. Future research should focus on overcoming current methodological limitations and advancing translational research to confirm these biomolecules' efficacy and safety in clinical orthodontic practice.

Preprint ARTICLE | doi:10.20944/preprints202405.0433.v1

A Novel Algorithm for Classifying Vegetation and Non-Vegetation Using Red Edge Slope Coefficient with Hyperspectral LCTF Imaging

Bayarsaikhan Uudus, Bayartsetseg Oyungerel, Yukihiro Takahashi, Erdenebaatar Dashdondog, Turtogtokh Tumenjargal, Narangarvuu Dashdondog, Qinxue Wang, Hasi Bagan, Begzsuren Tumendemberel

Subject: Environmental And Earth Sciences, Ecology Keywords: Hyperspectral Imaging; Liquid Crystal Tunable Filter; Red Edge Slope Coefficient; Spectral Reflectance; Vegetation Classification; Remote Sensing Algorithms

Online: 8 May 2024 (15:28:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0332.v1

Differential protective effect of zinc and magnesium for the hepatic and renal toxicity induced by acetaminophen and potentiated with ciprofloxacin in rats

Alexandra Moraru (Ciocan), Diana C. Ciubotariu, Cristina Mihaela Ghiciuc, Catalina Elena Lupusoru, Mihnea Eudoxiu Hurmuzache, Radu Crișan-Dabija

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: magnesium chloride (MgCl2); zinc gluconate (ZnG); liver diseases; kidney diseases

Online: 6 March 2024 (13:55:48 CET)

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Background: The purpuse was to investigate the influence induced by magnesium chloride (MgCl2) and zinc gluconate (ZnG) supplementation on liver and kidney injuries experimentally-induced with acetaminophen (AAPh) and potentiated by ciprofloxacin addition in rats. Material and methods: The experiment was performed on 5 animals groups: group 1 – control, treated for 6 weeks with normal saline, 1mL/kg; group 2 – AAPh, treated for 6 weeks with AAPh, 100 mg/ kg/day; group 3 – AAPh+C, treated AAPh 100 mg/kg/ day for 6 weeks and ciprofloxacin, 50mg /kg/day, only in the last 14 days of the experiment; group 4 – AAPh+C+Mg, with the same treatment as group 3, but, and in the last 14 days, MgCl2 10 mg/ kg/day was added; group 5 – AAPh+C+Zn, with the same treatment as group 3, but, and in the last 14 days, zinc gluconate (ZnG),10 mg/kg/day was added. All administrations were performed by oral gavage. At the end of the experiment, the animals were sacrificed and blood samples were collected for biochemistry examinations. Results: Treatment with AAPh for 6 weeks determined an alteration of the liver function (increases in alanine aminotransferase, aspartate aminotransferase, lactic dehydrogenase and, and gamma-glutamyl transferase) and of renal function (increases in serum urea and creatinine) (P < 0.001 group 2 vs. group 1 for all mentioned parameters). Also, the antioxidant defense capacity was impaired in group 2 vs. group 1 (superoxide dismutase and glutathione peroxidase activity decreased in group 2 vs. group 1, 0.001 < P < 0.01, respectively 0.01 < P < 0.05). The addition of ciprofloxacin, 50 mg/kg/day during the last 14 days resulted in further increases in alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase, urea and creatinine (0.01 < P < 0.05, group 3 vs. group 2). MgCl2 provided a slight protection against liver enzymes increase and a more pronounced protection against the increase in serum urea and creatinine (0.001 < P < 0.01 group 4 vs. group 3). MgCl2 provided a slight protection against the decrease in superoxide dismutase (0.01 < P < 0.05 group 4 vs. group 3), but not against decrease of glutathione peroxidase. The improvement of mentioned parameters could also be seen in case of ZnG, to a higher extent especially in the case of alanine aminotransferase and lactic dehydrogenase (0.01 < P < 0.05 group 5 vs. group 4). Conclusions: This study represents a furthermore proof for beneficial effect of magnesium and zinc salts against toxicity induced by different agents, including antibacterials added to the analgesic and antipyretic acetaminophen; the protection is proven on the liver and kidney’s function; the antioxidant profile improvement has a key role, especially in case of zinc gluconate.

Preprint ARTICLE | doi:10.20944/preprints202402.1759.v1

Synthesis and Catalytic Activity of 1,2-Benzenediamine-Derived Organocatalysts Based on (1R,2R)-Cyclohexane-1,2-diamine

Luka Ciber, Klara Klemenčič, Ana Golob, Helena Brodnik, Franc Požgan, Jurij Svete, Bogdan Štefane, Uroš Grošelj

Subject: Chemistry And Materials Science, Organic Chemistry Keywords: asymmetric organocatalysis; H-bond donor organocatalysts; (1R,2R)-cyclohexane-1,2-diamine; benzene-1,2-diamines; reduction; nucleophilic aromatic substitution; reductive alkylation; arylation; acylation; sulfonation

Online: 29 February 2024 (20:12:32 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.0969.v1

Gene Polymorphisms LEP, LEPR, 5HT2A, GHRL, NPY and FTO - Obesity Biomarkers in Metabolic Risk assessment: A Retrospective Pilot Study in Overweight and Obese Population in Romania

Ovidiu Nicolae Penes, Bernard Weber, Anca Lucia Pop, Mihaela Bodnarescu-Cobanoglu, Valentin Nicolae Varlas, Aleksandru Serkan Kucukberksun, Dragos Cretoiu, Roxana Georgiana Varlas, Cora Zetu

Subject: Medicine And Pharmacology, Endocrinology And Metabolism Keywords: genes; LEP; LEPR; GHRL; 5HTR2A; NPY; FTO; obesity; genotype; risk; cardiometabolic

Online: 19 February 2024 (11:50:18 CET)

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Genome-wide association studies (GWAS) have successfully revealed numerous susceptibility loci for obesity. PREDATORR study (2014) shows that in Romania, 34,6% of adults aged 20-79 y/o are overweight, 31,4% are obese with a high risk of cardiometabolic complications, a number that puts almost 67% of Romania's population in the abnormal weight group. Our study aims to investigate the current staus of genetic foundation in metabolic disease associated with obesity, applied to a pilot group of patients specifically examining the impact of known polymorphisms and their haplotype of six food intake-regulating genes: leptin (LEP), leptin receptor (LEP-R), serotonin receptor (5HTR2A), ghrelin (GHRL), neuropeptide Y (NPY) and fat-mass and obesity-associated (FTO) with the following polymorphisms: LEP A-2548G, LEPR A-223G, 5HTR2A G-1439A, GHRL G-72T, NPY T-29063C, FTO A-T and body mass index (BMI). A notable link between the LEP-2548 rs7799039 gene's AG genotype and the risk of obesity was observed, particularly pronounced in males aged 40-49, with an approximately sevenfold increased likelihood of obesity. The 5HTR2A rs6311 AA genotype was associated with a higher BMI, not statistically significant. The FTO rs9939609 gene's AA genotype emerged as a significant predictor of obesity risk. Besides these significant findings, no substantial associations were observed with the LEPR, 5HTR2A, GHRL and NPY genes. Haplotype association analysis showed a suggestive indication of GRGMLA (rs7799039, rs1137101, rs6311, rs696217, rs16139, rs9939609 sequence) haplotype with susceptibility effect towards obesity predisposition. Linkage disequilibrium (LD) analysis showed statistically significant associations between LEP and LEPR gene (p = 1e-04), LEP and GHRL gene (p = 0.0047), GHRL and FTO gene (p=0.03). The outcomes of this study, to our knowledge, one of the very few on the Romanian population, aimed to be a starting point for further research on the targeted interventional strategies to reduce cardiometabolic risks.

Preprint ARTICLE | doi:10.20944/preprints202407.1171.v1

Geochemical and Thermodynamic Study of Formation Water for Reservoir Management in Bibi Hakimeh Oil and Gas Field, Iran

Seyed Hossein Hashemi, Amir Karimian Torghabeh, Abas Niknam, Seyed Abdolrasoul Hashemi, Mahmoudy Gharaie, Nuno Pimentel

Subject: Engineering, Energy And Fuel Technology Keywords: oil and gas operations; , mineral ions; precipitation; formation water; geochemistry

Online: 16 July 2024 (00:13:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1955.v1

Manufacturing and Functional Characterization of Graphite/Metal Composite Materials for High Voltage Electric Motors

Radu Mirea, Razvan Ene, Dragoș Ene

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: graphite; carbon-metal composites; high voltage; pitch

Online: 28 August 2024 (02:56:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1010.v1

Tracking Phytoplankton Biomass amid Wildfire Interference Using Landsat 8 OLI

Sassan Mohammady, Kevin J. Erratt, Irena F. Creed

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: chlorophyll-a; freshwater; phytoplankton; remote sensing; wildfire

Online: 14 August 2024 (08:21:08 CEST)

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The increasing frequency and severity of phytoplankton blooms worldwide highlight the need for advancements in monitoring technologies. Optical remote sensors, such as Landsat, have proven to be a cost-effective method for large-scale, near-real-time assessments of phytoplankton biomass in lakes. However, its effectiveness is often compromised by atmospheric interferences like clouds, dust, and wildfire smoke, which can obscure the clear-sky conditions essential for accurate remote sensing. While partial atmospheric correction (removing only the Rayleigh effect) is commonly applied to address these interferences, it remains inadequate for mitigating the impact of wildfire smoke. This study investigates the potential of Landsat's coastal/aerosol band (B1) for assessing wildfire smoke interference effects on Chlorophyll-a (Chl-a) retrieval models, which serve as proxies for phytoplankton biomass. We employed cluster analysis of B1 values to create a screening system based on aerosol reflectance, categorizing smoke interference into low, moderate, and high levels. Subsequently, we applied both partial (Rayleigh-corrected reflectance) and full (Landsat 8 Level 2 surface reflectance) atmospheric corrections before developing the Chl-a retrieval models. Excluding high wildfire smoke interference (B1 > 0.07) from the Chl-a calibration dataset significantly enhanced model performance, increasing the r-squared value from approximately 0.55 to 0.80. Moderate smoke interference (0.05 < B1 < 0.07) yielded results comparable to low-interference conditions. Notably, Rayleigh-corrected reflectance, even without additional aerosol band filtering, achieved higher r-squared values for the Chl-a retrieval model than full atmospheric correction. B1 thus proves to be a valuable tool for identifying low smoke-impacted observations, offering an effective method to monitor phytoplankton biomass amid increasing wildfire activity and improving the capacity to monitor aquatic environments in a changing global landscape.

Preprint ARTICLE | doi:10.20944/preprints202407.2164.v1

Vortex Characterisation and Parametric Study of Miniature Vortex Generators and Their Near Field Boundary Layer Effects

Gilles De Baets, András Szabó, Péter Tamás Nagy, György Paál, Maarten Vanierschot

Subject: Engineering, Mechanical Engineering Keywords: Drag reduction; Boundary layer interaction; Miniature Vortex Generator; Transition delay

Online: 26 July 2024 (10:27:04 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202406.1617.v1

Recombinant C-terminal Catalytic Domain of Rat L-gulono Lactone Oxidase Produced in Bacterial Cells Is Enzymatically Active

Abdul Aziz Mohamed Gad, Anna Gora-Sochacka, Agnieszka Sirko

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Gulonolactone oxidase; recombinant protein; GULO activity; His-tag

Online: 24 June 2024 (08:44:01 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202406.1300.v1

Atomic-Scale Structural and Magnetic Coupling Properties of Twin Boundaries in LiFe5O8 Film

Kun Liu, Jiankang Li, Songyou Zhang

Subject: Chemistry And Materials Science, Electronic, Optical And Magnetic Materials Keywords: lithium ferrite; twin boundaries; magnetic; electron microscopy

Online: 19 June 2024 (12:57:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1054.v1

From Cow to Climate: Tracing the Path of Dairy Sustainability: Unveiling the Impact on Sustainable Development Goals through Bibliometric and Literature Analysis

Mwirigi Douglas, Maria Fekete-Farkas, Borbély Csaba

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: dairy farming; sustainability; sustainable development goals; bibliometric analysis; sustainable practices; environmental impact; milk production

Online: 19 June 2024 (11:00:21 CEST)

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Preprint REVIEW | doi:10.20944/preprints202406.0517.v1

Phase I–IV Drug Trials on Hepatocellular Carcinoma in an Asian Population: A Systematic Review of Ten Years Studies

Alok Raghav, Goo Bo Jeong

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: Hepatocellular carcinoma; Systematic; Asian Population; Treatment

Online: 10 June 2024 (06:46:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1049.v1

Study on Factors Influencing Forest Distribution in Barcelona Metropolitan Region

Xu Zhang, Blanca Arellano, Josep Roca

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: forest system; climate change; ecological environment; NDVI; urban expansion; sustainable development

Online: 15 May 2024 (13:41:00 CEST)

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Preprint REVIEW | doi:10.20944/preprints202405.0824.v1

Interdisciplinary Insights into Short Video Addiction: Integrating Psychological and Brain imaging Approaches in a Comprehensive Review

Tongshu Li, Huafang Liu, Xiaolong Liu

Subject: Social Sciences, Psychology Keywords: short video addiction; Tiktok; psychology; brain imaging; fMRI

Online: 13 May 2024 (09:39:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1999.v1

Exploring Urban Amenity Accessibility Within Residential Segregation: Evidence from Seoul's Apartment Housing

Gyoungju Lee, Beomsoo Jeong, Seungwook Go

Subject: Social Sciences, Urban Studies And Planning Keywords: Residential segregation; Urban Amenity Accessibility; Segregation index

Online: 30 April 2024 (11:50:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1168.v1

Spatial Development and Coupling Coordination of Society-Physics-Informational Smart City：A Case Study on Thirty Capitals in China

Chao Wang, Changhao Zhu, Mingrun Du

Subject: Social Sciences, Geography, Planning And Development Keywords: Smart City; SPI Model; Tri-dimensional Framework; Dagum Gini Coefficient; BP Neural Networks

Online: 17 April 2024 (13:07:31 CEST)

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Preprint CASE REPORT | doi:10.20944/preprints202403.1054.v1

Cibenzoline Succinate Poisoning and Cardiac Arrest Treated with Venoarterial Extracorporeal Membrane Oxygenation after Small Overdose: A Case Report

Hiroki Nawa, Yuya Yoshimura, Tatsuya Nodagashira

Subject: Medicine And Pharmacology, Emergency Medicine Keywords: cibenzoline succinate; drug toxicity; drug interaction; Extracorporeal Membrane Oxygenation

Online: 18 March 2024 (14:27:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0680.v1

Crack Detection in Orthographic Road Images Based on EC-YOLOX Algorithm

Lishuang Sun, Zeyu Liu, Zhiwei Xie

Subject: Engineering, Transportation Science And Technology Keywords: crack detection; Shallow features; YOLOX; ECA attention model; IOU loss; distortion correction

Online: 12 March 2024 (08:18:47 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.0966.v1

Genetic Variability and Interrelationships of Grain Quality, Cooking Quality and Nutritional Quality Traits in Cowpea: Implication for Cowpea Improvement

Michael M. Chipeta, Esnart Yohane, Jessica Kampanje-Phiri, John Kafwambira

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Consumer-preferred traits; cowpea, genetic variability; interrelationships; quality traits

Online: 19 February 2024 (03:32:06 CET)

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Preprint REVIEW | doi:10.20944/preprints202402.0255.v1

Environmental Risk Assessment Scenarios of Specific NGT Applications in Brassicaceae Oilseed Plants

Franziska Koller, Michael Cieslak, Andreas Bauer-Panskus

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: new genomic techniques (NGT); genetically engineered organisms; genome editing; risk assessment; unintended effects in NGT plants

Online: 5 February 2024 (13:54:38 CET)

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Preprint ARTICLE | doi:10.20944/preprints201609.0085.v2

Modeling and Simulation of Passenger Flow Distribution in Urban Rail Transit Hub Platform

Long Gao, Limin Jia

Subject: Computer Science And Mathematics, Computational Mathematics Keywords: passenger flow distribution model; simulation design; performance evaluation; passenger flow volume; service level; urban rail transit hub platform

Online: 2 December 2016 (07:52:00 CET)

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Preprint ARTICLE | doi:10.20944/preprints201610.0037.v1

A Multi-Objective Collection-Distribution Center Location and Allocation Problem in a Closed-Loop Supply Chain for the Chinese Beer Industry

Kang Kai, Xiaoyu Wang, Yanfang Ma

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: collection-distribution center; closed loop supply chain; fuzzy random variable; particle swarm optimization

Online: 11 October 2016 (11:02:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.1855.v1

Antimicrobial Susceptibility of Uropathogenic Escherichia coli with Analysis of Impact of Socio-Economic Factors in Low, Medium and High-Income Countries

Meher Rizvi, Maria Khan, Amina AL Jardani, Ujjala Ghoshal, Zaaima AL Jabri, Mohammad Ahanjan, Azza AL Mamari, Nawal AL Shizawi, Hiba Sami, Abdullah Balkhair, Adila Shaukat, Alwarith Nasser Salem Alkharusi, Abdulrahman Almahrouqi, Afreenish Hassan, Ajay Kumar, Amal Malehi, Amina Gul, Ashima Singh, Asma Said Hamed AL Shidhani, Areena Hoda Siddiqui, Aruna Poojary, Azza AL Rashdi, Bradley Langford, Dmytro Stepanskyi, Abbas Dolatabadi, Aisha Al Mufraji AL Mufraji, Elham Said Ahmed AL Risi, Garima Kapoor, Isabella Princess, Hatim Ali Eltahir, Hilal Al Sidairi, Kaitlyn Dougherty, Katia Iskandar, Ken Masters, Ibrahim Khalaf Hamdan AL Busaidi, Laila AL Yazidi, Mahfuza Nasrin, Mahmood Salim AL Subhi, Mallika Sengupta Mallika Sengupta, Manisha Khandait, Nada Khalfan AL Tamtami, Nada Khafan Alsiyabi, Nawal AL Kindi, Nazla Musthafa Luthfee, Neha Shreshtha, Nihal Mohamed Amur AL Riyami, Noora Hilal Ali AL Busaidi, Nupur Goel, Oksana Ishchenko, Omnia Mohamed Elnabawy Ahmed Taher, Pragnya Paramita Jena, Rajni Ekadashi, Razan Zadjali, Reba Kanungo, Sara Abolghasemi, Salima Al-maqbali, Sanjay Jaju, Sayantan Banerjee, Shadma Yaqoob, Shahnaz Sali, Shafqat Husnain Khan, Shalini Malhotra, Stephen Hughes, Sundas Shaukat, Syed Mohammed Atif, Vrushali Vishwas Patwardhan, Victorien Dougnon, Wahid Khan, Walid Wali, Zakariya AL Muharrmi, Zeeshana Basit, Jasashree Choudhury, Rachita Pravalina, Sanjeev Singh, Sarman Singh, Neelam Taneja, Raman Sardana, Pawan Kapoor, Rajeev Soman, Rashid Al Abri

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: community acquired UTI; Escherichia coli; antimicrobial susceptibility; Indian subcontinent; MENA; GDP; temperature

Online: 24 September 2024 (12:32:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0882.v1

Acute Kidney Disease following Acute Kidney Injury in Children—A Retrospective Observational Cohort Study on Risk Factors and Outcomes

Flavia Chisavu, Lazar Chisavu, Viviana Ivan, Adalbert Schiller, Adelina Mihaescu, Luciana Marc, Ramona Stroescu, Ruxandra Maria Steflea, Mihai Gafencu

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: acute kidney disease; children; mortality; chronic kidney disease

Online: 15 April 2024 (04:46:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.1824.v1

Longitudinal Fecal Microbiota Profiles in a Cohort of Non-Hospitalized Adolescents and Young Adults with COVID-19: Associations with SARS-CoV-2 Status and Long-Term Fatigue

Christine Olbjørn, Milada Hagen, Aina Fossum Moen, Lise Beier Havdal, Silke Lauren Sommen, Lise Lund Berven, Espen Thiis-Evensen, Tonje Stiansen-Sonerud, Joel Selvakumar, Vegard Bruun Bratholm Wyller

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: SARS-CoV-2; COVID-19; fatigue; post-COVID-19 condition; post-infective fatigue syndrome; microbiota; Faecalibacterium prausnitzii; Sutterella wadsworthensis

Online: 24 September 2024 (09:20:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0878.v1

Growth, Photosynthesis and Yield Responses of Common Wheat to Foliar Application of Methylobacterium symbioticum under Decreasing Chemical Nitrogen Fertilization

Francesco Valente, Anna Panozzo, Francesco Bozzolin, Giuseppe Barion, Pranay Kumar Bolla, Vittorio Bertin, Silvia Potestio, Giovanna Visioli, Yu Wang, Teofilo Vamerali

Subject: Environmental And Earth Sciences, Sustainable Science And Technology Keywords: Bio-fertilizer; Bio-stimulant; Plant growth promoting bacteria; Leaf senescence; Stomatal conductance; Sustainable agriculture; Nitrogen-fixing bacteria; Methylobacterium symbioticum; wheat.

Online: 13 August 2024 (11:30:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1951.v1

Evaluation of the Correlation Between Depression Intensity and Inflammation Levels in Patients with Major Depressive Disorder: A Case-Control Study

Radu Gavril, Petru-Romeo Dobrin, Vlad-Teodor Iacob, Andreea-Cristina Bejenariu, Raluca Gavril, Alin-Constantin Pinzariu, Mihaela Moscalu, Ioana Silistraru, Cristinel Stefanescu

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: Inflammation; depression; inflammatory markers

Online: 24 July 2024 (17:54:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0557.v1

Assessment of Platelet Aggregation and Thrombin Generation in Patients with Familial Chylomicronemia Syndrome Treated with Volanesorsen: A Cross-Sectional Study

Ilenia Lorenza Calcaterra, Renata Santoro, Nicoletta Vitelli, Ferdinando Cirillo, Guido D'Errico, Cornelia Guerrino, Giovanna Cardiero, Maria Donata Di Taranto, Giuliana Fortunato, Gabriella Iannuzzo, Matteo Nicola Dario Di Minno

Subject: Medicine And Pharmacology, Internal Medicine Keywords: Familial Chylomicronemia Syndrome; severe hypertriglyceridemia; Volanesorsen; antisense oligonucleotide; Platelets; thrombin generation

Online: 8 July 2024 (09:10:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.2151.v1

Synthesis and Antiproliferative Effect of New Alkyne-Tethered Vindoline Hybrids Containing Pharmacophoric Fragments

Etelka Ferenczi, Péter Keglevich, Bizhar Ahmed Tayeb, Renáta Minorics, Dávid Papp, Gitta Schlosser, István Zupkó, László Hazai, Antal Csámpai

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: vindoline; imatinib; erlotinib; chalcone; hybrid molecules; Sonogashira reaction; antiproliferative effect; selectivity; ovarian cancer

Online: 31 May 2024 (12:12:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1657.v1

Upscaling and Risk Evaluation of the Synthesis of the 3-5-Diamino-1H-Pyrazole, Disperazol

Charlotte Uldahl Jansen, Katja Egeskov Grier, Jens Bo Andersen, Louise Dahl Hultqvist, Martin Nilsson, Claus Moser, Michael Graz, Tim Tolker-Nielsen, Michael Givskov, Katrine Qvortrup

Subject: Chemistry And Materials Science, Organic Chemistry Keywords: biofilm; dispersal; pyrazole; c-di-GMP; large scale synthesis; flow chemistry; safety; dust analysis; Pseudomonas aeruginosa; preclinical

Online: 27 May 2024 (09:46:34 CEST)

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Preprint REVIEW | doi:10.20944/preprints202403.1341.v1

Covid19 and Pregnancy: Infected Mothers and Premature Babies?

Rita Franco, Federica Perelli, Vitalba Gallitelli, Marco Parasiliti, Annalisa Vidiri, Giovanna Palomba, Marta Bisanti, Amelia Spanò, Adele Silvagni, Alessandra Lopez, Giuseppe Gullo, Gaspare Cucinella, Anna Franca Cavaliere

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: SARS-CoV-2; COVID-19; preterm birth; pregnancy outcomes; obstetric outcomes

Online: 22 March 2024 (11:23:27 CET)

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Preprint REVIEW | doi:10.20944/preprints202403.0831.v1

Wearable Biosensor Technology in Education: A Systematic Review

María A. Hernández-Mustieles, Yoshua E. Lima-Carmona, Maxine A. Pacheco-Ramírez, Axel A. Mendoza-Armenta, José Esteban Romero-Gómez, César F. Cruz-Gómez, Diana C. Rodríguez-Alvarado, Jesús G. Cruz-Garza, Alejandro Arceo, Mauricio A. Ramírez-Moreno, Jorge de J. Lozoya-Santos

Subject: Engineering, Bioengineering Keywords: Biometrics; Education; NeuroEducation; Wearable Biosensor Technology

Online: 14 March 2024 (07:54:18 CET)

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Preprint ARTICLE | doi:10.20944/preprints202404.1225.v1

Solutions for the System of Nonlinear Mixed Variational Inequality Problems

H. Gissy, A. A. H. Ahmadini, Salahuddin .

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: System of nonlinear mixed variational inequality problem; Inverse relaxed monotonicity; Existence; Stability

Online: 18 April 2024 (11:24:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0589.v1

Synthetic Image Generation using Conditional GAN Provided Single Sample Face Image

IQBAL MUHAMMAD ALI, Waqas Jadoon, Soo Kyun Kim

Subject: Computer Science And Mathematics, Computer Vision And Graphics Keywords: Convolutional Neural Network (CNN); Single Sample Per Person (SSPP); Conditional Generative Adversarial Network (CGAN)

Online: 8 April 2024 (16:59:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201608.0075.v3

Lobatto-Milstein Numerical Method in Application of Uncertainty Investment of Solar Power Projects

Mahmoud A. Eissa, Boping Tian

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: stochastic differential equation; numerical simulation; real option; renewable energy; Egypt

Online: 30 January 2017 (12:04:34 CET)

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Preprint ARTICLE | doi:10.20944/preprints202407.0549.v1

Advanced Quantification of Receptor–Ligand Interaction Lifetimes via Single-Molecule FRET Microscopy

Lukas Schrangl, Vanessa Mühlgrabner, René Platzer, Florian Kellner, Josephine Wieland, Reinhard Obst, Jose L. Toca-Herrera, Johannes B. Huppa, Gerhard J. Schütz, Janett Göhring

Subject: Biology And Life Sciences, Biophysics Keywords: single-molecule FRET; single-molecule microscopy; receptor-ligand interaction; T cell receptor; bond lifetime quantification; T cell activation; antigen sensitivity; simulation; survival analysis

Online: 9 July 2024 (03:56:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0703.v1

Safety and Immunogenicity of the Intranasal Vaccine Candidate Mambisa and the Intramuscular Vaccine Abdala Used as Booster Doses for COVID-19 Convalescents: A Randomized Phase 1–2 Clinical Trial

Gilda Lemos-Pérez, Yinet Barrese-Pérez, Yahima Chacón-Quintero, Rolando Uranga-Piña, Yisel Avila-Albuerne, Iglermis Figueroa-García, Osaida Calderín-Marín, Martha M. Gómez-Vázquez, Marjoris Piñera-Martínez, Sheila Chávez-Valdés, Ricardo Martínez-Rosales, Lismary Ávila-Díaz, Amalia Vázquez-Arteaga, Hany González-Formental, Giselle Freyre-Corrales, Edelgis Coizeau-Rodríguez, Miladys Limonta-Fernández, Marta Ayala-Avila, Eduardo Martínez-Díaz, Eulogio Pimentel-Vazquez, Gerardo Enrique Guillén-Nieto

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: SARS-CoV-2; COVID-19 vaccines; convalescents; booster; intranasal; intramuscular; vaccination; Cuba

Online: 11 June 2024 (12:00:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0147.v1

Examining Chlorophyll Extraction Methods in Sesame Genotypes: Uncovering Leaf Coloration Effects and Anatomy Variations

Muez Berhe Gebremedhin, Jun You, Komivi Dossa, Donghua Li, Rong Zhou, Yanxin Zhang, Linhai Wang

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Carotenoids Content; Chloroplast Ultrastructure; Leaf Disk Positions; Sesamum indicum; SPAD value Index

Online: 3 May 2024 (11:22:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0064.v1

Analysing Spatial Distribution in Cattle within a Virtual Fence System

Silje Marquardsen Lund, Johanne Holm Jacobsen, Maria Gytkjær Nielsen, Marie Ribergaard Friis, Natalie Hvid Nielsen, Nina Østerhaab Mortensen, Regitze Cushion Skibsted, Magnus Fjord Aaser, Søren Krabbe Staahltoft, Dan Bruhn, Christian Sonne, Aage Kristian Olsen Alstrup, Cino Pertoldi

Subject: Biology And Life Sciences, Behavioral Sciences Keywords: cattle; virtual fencing; Nofence©; GPS based system

Online: 2 April 2024 (12:39:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.0398.v1

An Immune Escape of Oral Squamous Cell Carcinoma Might Be Different in the Originating-Epithelium, Keratinized or Non-keratinized

Yoshiaki Kistukawa, Chonji Fukumoto, Toshiki Hyodo, Yuske Komiyama, Ryo Shiraishi, Aya Koike, Shuma Yagisawa, Yosuke Kunitomi, Tomonori Hasegawa, Wataru Kotani, Kazuyuki Ishida, Takahiro Wakui, Hitoshi Kawamata

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: immune escape; tumor immunity; immune checkpoint; oral squamous cell carcinoma; programmed death receptor-1 (PD-1); programmed cell death 1-ligand 1 (PD-L1); CD47

Online: 7 March 2024 (07:49:57 CET)

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Preprint ARTICLE | doi:10.20944/preprints202409.0578.v1

Point of Common Connection Voltage Modulated Direct Power Control with Disturbance Observer to Increase of Renewable Energy Acceptance in Power System

Yong Woo Jeong, Woo Young Choi

Subject: Engineering, Electrical And Electronic Engineering Keywords: Grid voltage modulated power control; Point of common connection; Energy storage system; Voltage source inverter; Disturbance observer; Total harmonic distortion

Online: 9 September 2024 (08:00:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0215.v1

IoT Integration of Failsafe Smart Building Management System

Hakilo Sabit, Thit Tun

Subject: Engineering, Electrical And Electronic Engineering Keywords: Internet of Things (IoT); Building Energy efficiency; Building Management System (BMS); MATLAB simulation model; Auxiliary bypass system; BMS Reliability; Smart buildings

Online: 3 September 2024 (11:52:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1988.v1

Investigating the Extent and Nature of the Primate Pet Trade on TikTok

Daisy Collins, Marco Campera

Subject: Social Sciences, Other Keywords: social media; Internet; online; marmoset; macaque; spider monkey; mona monkey; capuchin monkey

Online: 28 August 2024 (09:14:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1408.v1

Experimental Investigation of Spreading Factor, Payload Length and Collision Effects in LoRaWAN Radio Interface

Luis Pires, José Martins

Subject: Engineering, Telecommunications Keywords: IoT; LPWAN; LoRaWAN; LoRa; Spreading Factor; Collision Effects; Interference; Payload Size

Online: 20 August 2024 (12:01:19 CEST)

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The number of physical devices connected to the Internet such as vehicles, household appliances and other "things" has been steadily increasing in recent years, thus forming the basis for the Internet of Things (IoT). IoT ecosystem extends beyond country borders and application domains, combining thousands of versatile devices that differ in terms of their structures, capabilities, and available resources. It is therefore not surprising that the landscape of wireless communication technologies and the degree of IoT devices available today is excessively broad and diverse. Interference between networks leads to frame collisions and consequent packet loss. Frame collisions occur when two or more packets overlap in time and frequency and use the same Long Range (LoRa) parameters, i.e. the same Spreading Factor (SF), Bandwidth (BW) and Carrier Frequency (CF). When most devices use the same configuration, collision probability is higher. The probability of frame collisions is also affected by traffic characteristics, particularly the periodicity of the transmission and the payload size. Larger payload sizes and more frequent transmissions accumulate with higher Time on Air (ToA) and channel occupancy [1]. Transmission powers and the location of the gateways also influences this situation. The aim of this experimental work is to verify the effects of collisions and interference in Long Range Wide Area Network (LoRaWAN), regarding the periodicity of transmissions and the payload sizes in a context of an inter-SF interference scenario. And to validate measuring tools like Received Signal Strength Indicator (RSSI), ToA and Packet Delivery Ratio (PDR) in the reliability of a network. We validate our conclusions by analyzing ToA according with RSSI and different data sizes, the RSSI for different SFs and different data sizes and finally the packet loss through the PDR for a better understanding of the reliability of packet transmission in our link. In the end we conclude that in an environment with inter-SF interference, the choice of SFs and packet lengths impacts ToA. When dealing with multiple devices near gateways, different SFs and varying packet lengths can lead to increased latency and longer ToA. Consequently, the risk of packet loss becomes more significant, especially if the signal-to-interference ratio (SIR) is low. This limitation will therefore affect scalability, particularly in Non-Line-Of-Sight (NLOS) scenarios.

Preprint ARTICLE | doi:10.20944/preprints202408.0870.v1

Focus Group Discussion Method as a Tool for Eliciting Local Community Views for Decision Making; a Case of the Save Valley Conservancy in the Southeast Lowveld of Zimbabwe

Joseph Shoko, Never Muboko, Edison Gandiwa

Subject: Social Sciences, Other Keywords: Focus Group Discussions; biodiversity; conservation; community

Online: 13 August 2024 (08:49:03 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202407.2608.v1

Pd EnCat™ 30 Recycling in Suzuki Cross-Coupling Reactions

Laura D’Andrea, Casper Steinmann

Subject: Chemistry And Materials Science, Organic Chemistry Keywords: Pd EnCat 30; catalyst recycling; Suzuki coupling; green chemistry; biaryl synthesis

Online: 2 August 2024 (09:30:50 CEST)

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Preprint REVIEW | doi:10.20944/preprints202407.1984.v1

Methods using Marine Aquatic Photoautotrophs Along the Qatari Coastline to Remediate Oil and Gas Industrial Water

Roda F. Al-Thani, Bassam T. Yasseen

Subject: Environmental And Earth Sciences, Pollution Keywords: heavy metals; macroalgae; mangrove; microorganisms; phycoremediation; seagrasses; seaweeds

Online: 25 July 2024 (00:20:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1207.v1

Mechanical Properties of an Extremely Tough 1.5 mol% Yttria Stabilized Zirconia Material

Frank Kern, Bettina Osswald

Subject: Chemistry And Materials Science, Ceramics And Composites Keywords: zirconia; mechanical properties; transformation toughening; microstructure

Online: 15 July 2024 (14:37:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0799.v1

An Image Compensation-based Range–Doppler model for SAR High-Precision Positioning

Kexin Cheng, Youqiang Dong

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: Range–Doppler model; Synthetic Aperture Radar; SAR Photogrammetry; image geolocation; geometric correction; accuracy improvement

Online: 10 July 2024 (14:20:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0812.v1

Consumption of snack foods by children and adolescents and their parents' knowledge about substances added to food

Agnieszka Kolmaga, Anna Garus-Pakowska

Subject: Public Health And Healthcare, Other Keywords: knowledge of parents; snack food; consumption; children and adolescents; food additives.

Online: 12 June 2024 (11:13:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0687.v1

Interference to Signalling Caused by Rolling Stock: Uncertainty and Variability on a Test Case

Sahil Bhagat, Andrea Mariscotti

Subject: Engineering, Electrical And Electronic Engineering Keywords: Electrical measurements; Data acquisition; Spectral analysis; Signal processing; Interference; Railways; Rolling stock; Uncertainty

Online: 11 June 2024 (11:45:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1607.v1

Properties of a Pressureless Sintered 2Y-TZP Material Combining High Strength and Toughness

Frank Kern, Bettina Osswald

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: zirconia; high toughness; microstructure; phase composition

Online: 24 May 2024 (08:38:08 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1840.v1

Generalized Pareto Distribution of Firm Sizes: Evidence from China

Yong Tao, Ruoxi Liu

Subject: Business, Economics And Management, Economics Keywords: ; Gibrat’ s law; generalized Pareto distribution; Zipf distribution; Pareto distribution; exponential distribution ;

Online: 28 April 2024 (10:31:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1447.v1

Optimal Battery Energy Storage Dispatch for the Day-Ahead Electricity Market

Julio Gonzalez-Saenz, Victor Becerra

Subject: Engineering, Electrical And Electronic Engineering Keywords: Collocation methods; optimal control; empirical battery model; day-ahead electricity market

Online: 25 March 2024 (08:31:26 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.1336.v1

Stable Heteroclinic Channel-based Movement Primitives: Tuning Trajectories using Saddle Parameters

Natasha Rouse, Kathryn Daltorio

Subject: Engineering, Control And Systems Engineering Keywords: biologically-inspired robots; robust control; optimal control; motion planning

Online: 23 February 2024 (09:56:00 CET)

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Preprint ARTICLE | doi:10.20944/preprints201608.0210.v1

Driving Factors of Smart City Construction in China—An Exploratory Method by Grounded Theory and Empirical Research

Qinghong Cui, Guangbin Wang

Subject: Engineering, Civil Engineering Keywords: smart city; smart city construction; urban sustainability; driving factors; grounded theory; empirical research

Online: 26 August 2016 (11:18:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201607.0067.v1

Design Methodology for an Energy Neutral Health Monitoring Wireless Sensor Node

Ankur Pokhara, Biswajit Mishra

Subject: Engineering, Electrical And Electronic Engineering Keywords: Energy Harvester, Neutrality, Perpetual, COTS, Health Monitoring WSN

Online: 22 July 2016 (15:14:29 CEST)

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Preprint REVIEW | doi:10.20944/preprints202407.2000.v1

Unveiling the Spectrum of Minor Genes in Cardiomyopathies: A Narrative Review

Caterina Micolonghi, Federica Perrone, Marco Fabiani, Silvia Caroselli, Camilla Savio, Antonio Pizzuti, Aldo Germani, Vincenzo Visco, Simona Petrucci, Speranza Rubattu, Maria Piane

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: cardiomyopathies; genetics; ARVC; DCM; HCM

Online: 25 July 2024 (09:41:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.0673.v1

Enhancing the Convergence Order from p to p+3 in Iterative Methods for Solving Nonlinear Systems of Equations without the Use of Jacobian Matrices

Alicia Cordero, Miguel Leonardo–Sepúlveda, Juan Torregrosa, María P. Vassileva

Subject: Computer Science And Mathematics, Computational Mathematics Keywords: Iterative methods; nonlinear systems; local convergence; Jacobian-free scheme

Online: 11 September 2023 (10:18:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.0636.v1

The Impact of Public Transportation Systems on Food Insecurity for Women in Allegheny County: A Call to Improve Well-Being within the Built Environment

Alex Firestine, Audrey J. Murrell

Subject: Business, Economics And Management, Business And Management Keywords: food insecurity; built environment; gender equality; well-being; disparities; food systems; social sustainability; transportation; walkability

Online: 11 September 2023 (07:18:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202107.0004.v3

A Conceptual Framework for Constructing Decision Policies by Processing the Possibilities in Mental Models of Dynamic Systems with the Cognitive Theory of Mental Models

Martin FG. Schaffernicht, Miguel López-Astorga, Cristian A. Rojas-Barahona, Ramón D. Castillo

Subject: Social Sciences, Decision Sciences Keywords: Mental Models; Dynamic Decision Making; Systems Thinking; Learning

Online: 24 August 2022 (03:49:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202108.0166.v1

Improvements in Modern Weapons Systems: The Use of Dielectric Materials for the Development of Advanced Models of Electric Weapons Powered by Brushless Homopolar Generator

Daniela Georgiana Golea, Lucian Stefan Cozma

Subject: Engineering, Automotive Engineering Keywords: electric weapons; rail gun; electromagnetic ammunition; hybrid technologies; plasma detonator.

Online: 6 August 2021 (14:00:09 CEST)

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Preprint REVIEW | doi:10.20944/preprints201909.0167.v1

Health Risks Associated with the Use of Water Mist Systems as a Cooling Intervention in Public Places in the Pilbara Region of Western Australia

Edmore Masaka, Sue Reed, Jacques Ooosthuizen, Margaret Davidson

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: opportunistic premise plumbing pathogens; water mist system; Legionella; Mycobacterium; Pseudomonas; Acanthamoeba; Naegleria; health risks

Online: 16 September 2019 (12:11:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0814.v1

Real World Analysis of Two Handheld Retinograph, Evaluation by Ophthalmologist and an Artificial Intelligence Algorithm

Pedro Romero‐Aroca, Benilda Fontova‐Poveda, Eugeni Garcia‐Curto, Aida Valls, Julian Cristiano, Monica Llagostera‐Serra, Cristian Morente‐Lorenzo, Isabel Mendez‐Marín, Marc Baget‐Bernaldiz

Subject: Medicine And Pharmacology, Ophthalmology Keywords: artificial intelligence; diabetic retinopathy; handheld retinal camera; public health; screening; smartphones; telemedicine; image quality

Online: 10 September 2024 (13:42:42 CEST)

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Preprint REVIEW | doi:10.20944/preprints202407.0134.v1

Revitalizing BCG Immunotherapy for Bladder Cancer: Nanotechnology and Bioengineering Approaches

Maoxin Lv, Shihao Shang, Kepu Liu, Yuliang Wang, Peng Xu, Hao Song, Jie Zhang, Zelong Sun, Yuhao Yan, Zheng Zhu, Hao Wu, Hao Li

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: nano-based drug delivery systems; bladder cancer; immunotherapy; BCG; anticancer nanoparticles

Online: 2 July 2024 (02:21:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1630.v1

Rapid, Selective, and Ultra-Sensitive Electronic Field Effect Detection of Escherichia coli

Liena Zaidan, Inna Novodchuk, Alexandru Nica, Alexander H.Xu, Christopher Lloyd, Reza Karimi, Joe Sanderson, Michal Bajcsy, Mustafa Yavuz

Subject: Engineering, Electrical And Electronic Engineering Keywords: Graphene; FET; Biosensor; E.coli

Online: 24 June 2024 (08:43:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202301.0477.v1

A Comparison and Co-relation Between Estimated Water Quality Parameters Using Band Ratio Algorithm of Sentinel-2 and Landsat-8 Data and Observed Water Quality Parameters for Kamuzu Reservoir Over Lilongwe River in Malawi, Africa

Bernard Chome, Satya Prakash

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Water quality; remote sensing; Sentinel-2; Landsat 8; TSM; CDOM; Secchi depth; Turbidity; Chlorophyll-a

Online: 26 January 2023 (09:12:01 CET)

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Water quality is the measure of chemical, physical and biological suitability of water in relation to natural effects and intended purpose which may affect human health and aquatic life. Assessment of water quality is very essential for the management of water resources and human health. Traditionally, in-situ measurements have been used to obtain the water quality parameters of the water bodies. However, with the availability of satellite images, researchers have shown that satellite images are a reliable tool that can be used to estimate water quality. Satellite image-derived water quality parameters provide extensive spatial extent and large temporal variations when compared to traditional in situ sample collection and laboratory measurements. The present work estimated several parameters for quality of water in the Kamuzu reservoir of Lilongwe River for the 2013-2020 period using Sentinel-2 and Landsat-8 satellite images. The band ratio algorithms were used to retrieve Chlorophyll a (Chl-a), Turbidity, Total Suspended Matter (TSM), Secchi depth, Coloured Dissolved Organic Matter (CDOM), and Cyanobacteria from the reservoir. Turbidity and TSM were compared with the in-situ data collected over the same period. The comparison indicated R² of 0.9 and 0.69 for TSM and Turbidity respectively from Sentinel-2 images whereas R² of 0.56 and 0.61 was obtained using Landsat 8 images which are quite encouraging. The other set of results included the spatial distribution maps of water quality parameters using Landsat-8 and Sentinel-2 satellite data. It was observed that the spatial distribution of water quality parameters, except for CDOM and Cyanobacteria, showed very good distribution and matches with the theoretical results. However, for CDOM and Cyanobacteria, the distribution was almost similar for the entire study area and the band ratio algorithm may not be able to estimate them quite reasonably. This research reiterates the need for the use of remote sensing in estimating the water quality parameters and may be a substitute to the in-situ data, in terms of spread and frequency, which is very common to most of the water bodies, across the globe.

Preprint ARTICLE | doi:10.20944/preprints202410.0460.v1

Circular Economy in the Agri‐Food System at the Country Level. Evidence from European Countries

FAHIMEH KHATAMI, Enrico Cagno, Rayeheh Khatami

Subject: Business, Economics And Management, Business And Management Keywords: Circular Economy; Agri-Food; Food Production; Food Waste; Panel Data Analysis; European Countries

Online: 7 October 2024 (11:10:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202410.0195.v1

Integration of Object Recognition, Color Classification and QR Decoding for the Purposes of Intelligent Robots

Radoslav Vasilev, Nayden Chivarov, Valentina Ivanova

Subject: Computer Science And Mathematics, Robotics Keywords: object recognition; color classification; QR decoding; mobile robots; dynamic environment; perceptual anchoring; artificial intelligence

Online: 2 October 2024 (15:05:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.1426.v1

Improving the Efficiency and Safety of Sentinel Stink Bug Eggs Using X-Rays

Evelyne Hougardy, Ronald P. Haff, Brian N. Hogg

Subject: Biology And Life Sciences, Insect Science Keywords: stink bug; egg parasitism; field monitoring; sentinel eggs; x-ray irradiation; egg sterilization

Online: 18 September 2024 (13:57:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.1318.v1

Cortical Organotypic Brain Slice Cultures to Examine Sex- and Age-Dependent Astrocyte-Mediated Synaptic Phagocytosis

Anastasiia Nagumanova, Lea R. Seeholzer, Barbara Di Benedetto

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: Organotypic brain slice culture; astrocyte; phagocytosis; synaptic elimination; prefrontal cortex; critical period; major depressive disorder

Online: 17 September 2024 (11:42:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.1311.v1

An In Vitro Assay to Measure Astrocyte-Dependent Synaptic Phagocytosis in Health and Major Depressive Disorder

Diego Julian Vesga-Jimenez, Eugenia Vivi, Barbara Di Benedetto

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: Confocal microscopy; astrocytes; phagocytosis; prefrontal cortex; major depressive disorder; Synaptic pruning

Online: 17 September 2024 (10:53:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0973.v1

Multi-objective Evolutionary Optimization of Transonic Natural Laminar Flow Wing at High Reynolds Number

Shaojun Luo, Zhili Tang, Yongbin Chen

Subject: Engineering, Aerospace Engineering Keywords: Variable-fidelity hierarchical evolutionary optimization; Pareto non-dominated solutions; Transition predicition; Natural laminar flow wing; Shock wave control technology

Online: 12 September 2024 (07:39:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0486.v1

ESG Reporting of Commercial Banks in Poland the Aspect of the New Requirements of the Directive on Corporate Reporting in the Field of Sustainable Development (CSRD)

Alina Matuszak-Flejszman, Sebastian Łukaszewski, Joanna Katarzyna Banach

Subject: Business, Economics And Management, Business And Management Keywords: commercial banks; ESG; CSRD directive; non-financial reporting; banks' challenges; green financing

Online: 6 September 2024 (08:09:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.2033.v1

Fractional Flow Reserve Implications for Clinical Decision Making in Coronary Artery Disease

Andrei Grib, Marcel Abras, Artiom Surev, Livi Grib

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: fractional flow reserve; coronary artery disease; visual assessment variability; clinical decision making

Online: 28 August 2024 (13:40:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1481.v1

Assessing the Effects of Citizen Climate Literacy and Attitudes on Their ‘Greening’ Behaviour in a Climate Change Hotspot Region of the Eastern Mediterranean

Katerina Papagiannaki, Vassiliki Kotroni, Konstantinos Lagouvardos

Subject: Environmental And Earth Sciences, Environmental Science Keywords: climate literacy; climate change; greening behaviour; Eastern Mediterranean

Online: 21 August 2024 (09:47:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0512.v1

Optimizing Schedules in Manufacturing: Unleashing the Power of Mathematical Optimization

João Carlos Silva, Sandro Carvalho, Gilberto Santos

Subject: Computer Science And Mathematics, Computational Mathematics Keywords: Mathematical Optimization; Manufacturing; Scheduling

Online: 7 August 2024 (13:59:28 CEST)

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Mathematical optimization offers a valuable approach to tackle Industry scheduling problems. By formulating the scheduling challenge as a mathematical problem, mathematical optimization enables efficient and effective decision-making processes. Mathematical optimization is particularly beneficial in complex scheduling scenarios, such as in networked manufacturing environments, where multiple jobs and resources need to be coordinated. By leveraging optimization models and algorithms, it becomes possible to generate optimal process plans, considering factors like job dependencies, resource availability, and timing constraints. Through mathematical optimization, organizations can achieve improved efficiency, reduced lead times, and enhanced utilization of resources. Rigorous mathematical formulations and optimization techniques enables to surpass traditional manual planning methods and brings forth powerful computational capabilities. By optimizing various scheduling objectives, from minimizing makespan to maximizing resource utilization, mathematical optimization provides organizations with valuable insights and actionable plans. The purpose of this study is to discuss scheduling solutions for multiple jobs in a networked manufacturing setting based on mathematical optimization process. The study analyses a solver-based approach to generate the optimal process plans for multiple jobs and compare it with a more traditional game-theoretic approach. The objectives aim to develop two solver-based model using Z3 and Gurobi to generate optimal process plans; implement a game-theoretic model to solve for the same set of scheduling problems, and compare the computational time, solution quality, and efficiency of both approaches. To achieve this, the methodology will start with the problem definition. Multiple jobs are to be scheduled on a set of parallel machines. Each job has predefined processing times, deadlines, and priorities. The objective is to minimize the total completion time and maximize machine utilization while meeting all deadlines.

Preprint ARTICLE | doi:10.20944/preprints202407.2607.v1

Comparative Genomics of Nectriaceae, including Freshwater Fungi Show Environment Adaptations and Conservation Strate-Gies for Fungi

Daniel Vasconcelos Rissi, Maham Ijaz, Christiane Baschien

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Nectriaceae family; Fungal lifestyles; Global warming; Genomic Adaptations

Online: 31 July 2024 (15:15:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1856.v1

Yoga and Swimming – A Symbiotic Approach with Positive Impact on Health and Athletes’ Performance

Rocsana Bucea-Manea-Țoniș, Andreea Natalia Jureschi (Gheorghe), Luciela Vasile

Subject: Biology And Life Sciences, Aquatic Science Keywords: yoga practice; social and health benefits; therapeutic approaches

Online: 24 July 2024 (16:28:38 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202407.1409.v1

A High-Gain Broadband Circularly Polarized Crossed Dipole Antenna

Chunping Liao, Wenyong Liu, Xianjing Lin

Subject: Physical Sciences, Radiation And Radiography Keywords: circular polarization; cross dipole; high gain; wide axial ratio bandwidth

Online: 17 July 2024 (12:45:20 CEST)

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Preprint REVIEW | doi:10.20944/preprints202406.2031.v1

Exploring the Dark Matter of Human Proteome: Emerging Role of Non-canonical Open Reading Frame (ncORF) in Cancer Diagnosis, Biology, and Therapy

Anni Ge, Curtis Chan, Xiaolong Yang

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: human proteome; ncORF; micropeptide; microprotein; cancer biology, therapy

Online: 28 June 2024 (13:48:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1631.v1

Painting Schizophrenia: An Empirical Investigation of the Self-Portraits and Portraits of Edvard Munch

Eric Bettelheim, Jingyi Liu, Paola Dazzan, Federico Turkheimer

Subject: Arts And Humanities, Art Keywords: Neuroaesthetics; Neurophysiology; Stylistics; Psychiatry; Schizophrenia; Anxiety; Bipolar Disorder; Vision; Perception; Self-portraits; Edvard Munch.

Online: 24 June 2024 (11:56:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1621.v1

Self Images: An Empirical Enquiry into Rembrandt’s Self-portraits and Portraits

Eric Bettelheim, Jingyi Liu, Paola Dazzan, Federico Turkheimer

Subject: Arts And Humanities, Art Keywords: Neuroaesthetics; Neurophysiology; Stylistics; Depression; Perception; Self-portraits; Rembrandt,

Online: 24 June 2024 (11:52:38 CEST)

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Preprint REVIEW | doi:10.20944/preprints202406.1005.v1

Critical Challenges in the Anodizing Process of Aluminium -Silicon Cast Alloys—A Review

Emel Razzouk, Daniel Koncz-Horvath, Tamás I. Török

Subject: Chemistry And Materials Science, Surfaces, Coatings And Films Keywords: aluminum-silicon cast alloys; anodizing; anodic layer; intermetallic compounds; microstructure; plasma electrolytic oxidation (PEO)

Online: 14 June 2024 (14:00:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0829.v1

Toward the Development of Garlic Varieties: The First Attempts

Ricardo Julián Licea-Moreno, Ángeles Rodríguez Haro, Juan Antonio Marín Martínez

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Allium sativum (L.); clonal selection; genotype-environment interaction; landrace; plant breeding; selection pressure

Online: 12 June 2024 (17:43:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1880.v1

Assessment of the Fungal Contaminants of Dried Fishes Sold in Open Markets in Awka, Nigeria

Uche Chukwurah, Chito Ekwealor, Nzube Ekpunobi

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Dried Fish; Molecular Identification; PCR; ; Aspergillus; Penicillium and Fusarium

Online: 29 May 2024 (06:35:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1593.v1

Microbiomes of Two Pest Fly Species of Pennsylvania Mushroom Houses

Joyce M. Sakamoto, Ikkei Shikano, Jason L. Rasgon

Subject: Biology And Life Sciences, Insect Science Keywords: Mushroom fly; microbiome; Lycoriella ingenua; Megaselia halterata; Wolbachia

Online: 24 May 2024 (11:53:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0300.v1

Toward Intraoperative Visual Intelligence: Real-Time Surgical Instrument Segmentation for Enhanced Surgical Monitoring

Mostafa Daneshgar Rahbar, George Pappas, Nabih Jaber

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Intraoperative surgery; monitoring surgical scene; convolutional neural network; U-Net; data augmentation; surgical tools segmentation; computer vision; image processing

Online: 7 May 2024 (02:32:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1780.v1

Design and Investigation of Hybrid Microfluidic Micromixer

Muhammad Waqas, Giedrius Janusas, Vytenis Naginevičius, Arvydas Palevicius

Subject: Engineering, Mechanical Engineering Keywords: Micro-mixing; Acoustic streaming; Acoustofluidics; Microfluidics; Mixing index

Online: 27 April 2024 (10:16:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1653.v1

The Evolution and Impact of Glacier Avalanches in Tibet Based on the Sentinel-2 Time-Series Images

Duo Chu, Drolma Lhakpa, Yong Nie, Zhaojun Zheng

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: Glacier avalanche; Cryospheric hazard; Sentinel-2; Field investigation; Tibet

Online: 25 April 2024 (10:15:06 CEST)

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Catastrophic mass flows originating from the high mountain cryosphere often cause hazard cascades. With increasing human activities in the alpine region and the sensitivity of glaciers, snow and permafrost to climate warming, the cryospheric hazard risks tend to be more active in the Tibetan Plateau(TP). The remoteness and inaccessibility of high mountain regions make the remote sensing technology the most effective approach for monitoring and investigating the cryospheric hazards. Exploring the evolution process and impact of ice avalanches and subsequent hazards are crucial to understand drivers and nature of mass flow process chain in order to prevent and mitigate potential hazard consequences. In this study, the glacier and ice-rock avalanches occurred in Arutso and Sedongpu basins in Tibet were investigated on the basis of Sentinel-2 time-series images and in-situ investigation, the evolution process of these events were reconstructed, and impacts and driving factors were analyzed. The massive Chamoli rock-ice avalanche occurred in February 2021 in the western Himalayas was also reviewed using using same methods. The study shows that Arutso glacier No. 53 (Arutso-53) avalanche completely melted away in July 2018 after two years from occurrence to final disappearance, while Arutso glacier No. 50 (Arutso-50) avalanche completely melted by the end of August 2023 after lasting for seven years. Four large-scale ice-rock avalanche and debris flow events in the Sedongpu basin in 2017 and 2018 not only had significant impacts on the river flow, landscape and geomorphologic shape in the basin, but also caused serious disasters in the basin and downstream. In March 2021, a small-scale ice-rock avalanche and debris flow event occurred again in the Sedongpu basin. The glacier and ice-rock avalanches occurred in Tibet area were mainly induced by climate warming, heavy precipitation and seismic activity, which acting on specific topographic and geomorphic structure of glacier properties in the high mountain regions. Catastrophic hazard events originating from the high-elevation glacier and ice-rock collapses in the mountain cryosphere and subsequent hazard cascades in the TP and Himalayas highlight the importance of mountain hazard monitoring, early warning systems and sustainable mountain development.

Preprint ARTICLE | doi:10.20944/preprints202404.0966.v1

Category-Based Effect on False Memory of People with Down Syndrome

Ching-Fen Hsu, Qian Jiang, Shi-Yu Rao

Subject: Social Sciences, Psychology Keywords: down syndrome; false memory; concept formation; nouns; verbs

Online: 16 April 2024 (02:21:41 CEST)

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Background: People with Down syndrome (DS) have a trisomy of chromosome 21 and marked deficits in verbal memory but relatively preserved visuospatial perception. Verbal memories are related to semantic knowledge. Little is known about the organization of semantic knowledge in people with DS, which was the aim of this study. Aims: The extent of false memory in people with DS was examined. Possible differences in the number of false memories induced by nominal and verbal themes were examined. Methods and Procedures: In the study phase, ten word lists with semantically related associates were presented. In the recognition phase, participants made judgments on whether each word had been represented previously as semantically related lures, old words, and semantically unrelated new words. Outcomes and Results: Differences in the processing of nominal and verbal theme-related lures were observed among people with DS. When processing nominal theme-related lures, people with DS showed delayed false positives. When processing verbal theme-related lures, people with DS showed no differences compared to controls. Similar patterns have been observed in people with DS when processing nominal theme-related associates and verbal theme-related associates. People with DS have delayed recognition of associates. When processing unrelated words, they showed significantly higher false positives than controls for both nominal and verbal eliciting themes. Further analyses of the themes revealed differences in false positives across syntactic categories among groups. Conclusions and Implications: People with DS showed a delayed recognition of associates and deviance in recognizing unrelated words in the nominal and verbal theme categories. People with DS were delayed in terms of nouns, but deviated with verbs in associated and unrelated words. Additionally, people with DS showed distinct patterns in processing five nominal lures and three verbal lures, suggesting that they formed false memories differently based on distinct syntactic categories. Thus, it was concluded that people with DS develop a deviant semantic structure. Category-based interventions for people with DS should be implemented in order to improve their semantic knowledge through lexical connections.

Preprint ARTICLE | doi:10.20944/preprints202404.0846.v1

Identifying the Impact Factors on the Land Market in Nepal from Land Use Regulation

Nab Raj Subedi, Kevin McDougall, Dev Raj Paudyal

Subject: Social Sciences, Urban Studies And Planning Keywords: land use regulation, land market, stakeholders, qualitative data analysis, impact factors.

Online: 12 April 2024 (10:25:56 CEST)

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Preprint REVIEW | doi:10.20944/preprints202404.0659.v1

Gerontogen as the Toxicology of Aging

Rahma Rahma, Agian Jeffilano Barinda

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: aging; senescence; toxicology; gerontogen; senotherapy

Online: 10 April 2024 (03:17:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0574.v1

A NLOS Ranging Error Mitigation Method for 5G Positioning in Indoor Environments

Jingrong Liu, Zhongliang Deng, Enwen Hu

Subject: Engineering, Telecommunications Keywords: 5G positioning; Ziv-Zakai Bound; non-line-of-sight mitigation; location estimation

Online: 9 April 2024 (07:33:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0505.v1

Inspiring Sustainability in Undergraduate Engineering Programs

Tina Griesinger, Kenneth Reid, David Knight, Andrew Katz, John Somers

Subject: Engineering, Other Keywords: environmental sustainability; engineering education; learning experiences; career interests

Online: 8 April 2024 (08:30:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0163.v1

Correlation Analysis of Tunnel Deformation and Internal Force in the Earthquake Based on Tunnel Inclination

Zhiyong Yang, Yin Liu, Can Chen

Subject: Engineering, Civil Engineering Keywords: Dynamic time history; seismic response; relative displacement; tunnel inclination

Online: 2 April 2024 (08:53:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1553.v1

Environmental Accounting Disclosures and Financial Performance of Listed Oil and Gas Companies in Nigeria: An Application of Driscoll-Kraay Standard Errors Approach

Adegboyega R. Afolabi, Olayemi Oluwadamilola Amosun, Solomon Oluwaseun Okunade, MaryAnn Njong Agbor

Subject: Business, Economics And Management, Finance Keywords: environmental accounting; financial performance; oil and gas companies; Nigeria; Driscoll-Kraay standard errors

Online: 26 March 2024 (10:48:56 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0757.v1

Direct and Indirect Effects of Mountain Heights on Heavy Rainfall in the Hokitika Region of New Zealand

Yang Yang, Ian Boutle, Stuart Moore, Trevor Keith Carey-Smith, John Crouch

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Heavy rainfall; orographic lifting; mountain blocking; cold front; sub-grid mountain height; dual-polarisation radar; Southern Alps

Online: 13 March 2024 (07:28:05 CET)

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