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Preprint ARTICLE | doi:10.20944/preprints202407.1784.v1

Emergency Mapping for Flood Events Using Satellite Imagery (Optical and/or Synthetic Aperture Radar) and Benchmarking between Open Source and Commercial Geospatial Analysis Tools

Nancy Alvan Romero, Wilson A. Suarez Alayza

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: weather; cyclone; emergency map; flood; satellite image; Peru

Online: 23 July 2024 (13:39:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1159.v1

Progressive Keratoconus Treatment with Transepithelial 2-Step Phototherapeutic Keratectomy Combined with Corneal Cross-Linking (CXL): Clinical Outcomes and Postoperative Management including Potential Complications, of the Modified Athens Protocol De

Anastasios John Kanellopoulos, Alexander J. Kanellopoulos

Subject: Medicine And Pharmacology, Ophthalmology Keywords: Ectasia; keratoconus; cornea crosslinking; excimer ablation; PRK; Athens Protocol

Online: 15 July 2024 (11:34:58 CEST)

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Purpose: To report a novel application of excimer ablation for normalization of central corneal refractive irregularity, combined with higher fluence CXL in the effective management and visual rehabilitation of progressive keratoconus. Methods: 17 cases with progressive keratoconus were treated with a corneal surface excimer laser ablation normalization using the topographyguided (Contura) myopic ablation for customized corneal re-shaping using a 6mm optical zone. The epithelial removal was accounted for by adding a -2.75 diopters correction in the topographyguided normalizing surface ablation followed by, a second, wavefront-optimized hyperopic excimer treatment of + 2.75 diopters at 6mm optical zone. The 2 sequential excimer ablations were followed by the corneal crosslinking (CXL). Visual acuity, refraction, and keratoconus documentation via keratometry, topography, and pachymetry, as well as endothelial cell density were evaluated over 36 months. Results: Keratoconus stabilized in all cases. The severity of keratoconus stage by Amsler-Krumeich criteria improved for the OD from an average 2.2 to 1. Mean UDVA showed marked improvement at one-year follow-up all values in decimal: from 0.21±0.18 pre-operative to 0.51±0.25 at 12 months, with small additional improvement through the 3 years to 0.51±0.16. CDVA respectively increased from 0.55±0.11 to 0.77±0.14 at 1 year, and to 0.79±0.16 at 3 years. Mean minimal corneal thickness decreased significantly from 466.74±34.25 µm to 396.17±45.17 µm (P<.01) as recorded the first year postoperatively and then slightly increased to 405.17±32.21 µm at the 3-year follow-up. Conclusions: We introduce herein initial clinical data with the use of novel, off-label therapeutic excimer laser surface ablation application: Designed to perform both epithelial removal and anterior corneal stroma reshaping, to be combined with CXL, in order to apply the Athens Protocol CXL with US excimer laser approved specifications.

Preprint REVIEW | doi:10.20944/preprints202406.0329.v1

Are Viruses Taxonomic Units? – A Protein Domain and Loop-Centric Phylogenomic Assessment

Gustavo Caetano-Anollés

Subject: Biology And Life Sciences, Virology Keywords: holobionts; hologenomes; LUCA; origin of viruses; phylogenomic reconstruction; process; protein structure; reductive evolution; superkingdom; syncytins

Online: 6 June 2024 (07:52:20 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1624.v1

Analysis of User Experience data and Methodology of application to improve the development of User Interface

Ellada Ismailova, Andrei Ermakov

Subject: Computer Science And Mathematics, Other Keywords: user experience, user interface, data analysis

Online: 24 May 2024 (09:56:15 CEST)

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Preprint REVIEW | doi:10.20944/preprints202308.1017.v2

Review of Nature-Based Echo-Hydraulic Aqua-Forest Technology for Coastal Resilience and Sea Level Rise Climate-Induced Adaptation

Olanrewaju Oladokun, Unberto Lazzaro

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Nature-based solution; seaweed; seagrass; platform; coastal protection

Online: 16 April 2024 (10:46:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1457.v1

Systemic Financial Risk Forecasting: A Novel Approach with IGSA-RBFNN

Yishuai Tian, Yifan Wu

Subject: Business, Economics And Management, Business And Management Keywords: Financial stress index; Risk prediction; AHM; CRITIC; IGSA-RBFNN

Online: 25 March 2024 (13:10:23 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.1177.v1

A New Approach to Achieving Implant Stability with Flexible Synthetic Polymer Bone Graft: An In Vitro Study

Zeynep Dilan Orhan, Levent Ciğerim

Subject: Medicine And Pharmacology, Dentistry And Oral Surgery Keywords: bone model; dental implant; implant stability; bone graft; flexible bone graft

Online: 20 March 2024 (13:01:02 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.1043.v1

Neural Information Organizing and Processing – Neural Machines

Iosif Iulian Petrila

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: neural information; neural machines; neural networks; sensors and actuators; nervous systems; artificial intelligence

Online: 18 March 2024 (16:14:14 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0743.v1

PointNet++ Network with Contextual Feature and Mutual Learning for Point Sets

Xi Hu, Xiaolan Xie

Subject: Computer Science And Mathematics, Computer Vision And Graphics Keywords: point cloud; part segmentation; deep learning; self-attention; object classification

Online: 13 March 2024 (10:18:11 CET)

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Preprint REVIEW | doi:10.20944/preprints202403.0650.v1

Developmental, Physiologic and Phylogenetic Perspectives on the Expression and Regulation of Myosin Heavy Chains in Craniofacial Muscles

Joseph Foon Yoong Hoh

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: Craniofacial muscles; myosin heavy chain; gene expression; myogenesis; neural regulation; thyroid hormone; muscle plasticity; phylogeny

Online: 11 March 2024 (17:36:17 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.0742.v2

On How to Measure the Subdivision Potential in Nanothermodynamics

Dick Bedeaux, Signe Kjelstrup

Subject: Physical Sciences, Thermodynamics Keywords: Nanothermodynamics; Subdivision potential; Porous media; Shape dependence; Scaling laws

Online: 6 March 2024 (04:15:04 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.0788.v2

Creating An Array Of Parallel Vortical Optical Needles

Paulius Šlevas, Sergej Orlov

Subject: Physical Sciences, Optics And Photonics Keywords: diffraction; optical engineering; spatial light modulator; Bessel beam; optical vorte; optical needle; focal line; translation of Bessel beams

Online: 15 February 2024 (09:43:18 CET)

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Preprint ARTICLE | doi:10.20944/preprints202309.2097.v1

Engineering a Computable Epiblast for in silico Modeling of Developmental Toxicity

Kaitlyn Barham, Richard Spencer, Nancy C. Baker, And Thomas B. B. Knudsen

Subject: Biology And Life Sciences, Toxicology Keywords: cellular dynamics; multicellular agent-based model; computer simulation; developmental toxicity.

Online: 29 September 2023 (12:02:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.1178.v1

Land use change scenarios building combining agricultural development policies, landscape planning approaches and ecosystem services assessment. The Campania Region (Italy) case-study

Elena Cervelli, Pier Francesco Recchi, Ester Scotto di Perta, And Stefania Pindozzi

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Land-use change; Land-use planning; Ecosystem services; Erosion; Climate change; Agricultural policies; Soil tillage

Online: 18 July 2023 (07:40:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202104.0395.v1

SynPred: Prediction of Drug Combination Effects in Cancer using Full-Agreement Synergy Metrics and Deep Learning

António J. Preto, Pedro Matos-Filipe, Joana Mourão, and Irina S. Moreira

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Deep-Learning; Interpretability; Omics; Biophysics; Drug Synergy; Cancer

Online: 14 April 2021 (17:44:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202010.0415.v1

Optical Sensing Approach to Recognition of Different Types of Particulate Matters for Sustainable Indoor Environment Management

Hosang Ahn, Jae Sik Kang, Gyeong-Seok Choi, and Hyun Jung Choi

Subject: Engineering, Architecture, Building And Construction Keywords: optical sensing; particulate matter; sustainable indoor environment; contaminant control

Online: 20 October 2020 (15:05:25 CEST)

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As climate changes, our daily life has been much influenced by abnormal meteorological phenomena such as heavy rainfall, heat wave, heavy snowfall, and fine dust. Atmospheric air quality is worsening day by day and indoor air quality is also affected by interconnected daily activities throughout the inside and outside of buildings and houses. Nowadays, pollutants from various sources are emitted, transformed by sunlight, vapor, and ozone and transported into the city from country to country. Due to these reasons, there have been high demands to monitor the transportation of particulate matters and improve air quality. Monitoring of pollutants and identification of type and its concentration enables us to track and control its generation and consequently find out the solution. However, monitoring of pollutants, especially, particulate matter generation and its transportation is still not fully operated in atmospheric air due to its open nature and meteorological factors. Even though indoor air is relatively easy to monitor and control than outdoor in the aspect of specific volume and contaminant source, but it still needs to consider the meteorological parameters because indoor air is not fully separated from the outdoor air flow and contaminants transportation. In this study, optical approach using spectral sensor was attempted to reveal the feasibility of wavelength and chromaticity values of reflected light from specific particles. From the analysis of reflected light of various particulate matters according to different liquid additives, parameter studies were performed to investigate which experimental conditions can contribute to the enhanced selective sensing of particulate matters. Five different particulate matters such as household dust, soil, talc powder, gypsum powder and yellow pine tree pollen were utilized and observed to elucidate the relationship between property of particulate matter and detected light spectrum. Applicable approaches to assist current particle matter sensors and improve the selective sensing were suggested.

Preprint ARTICLE | doi:10.20944/preprints202008.0271.v1

Soil Loss and Sediment Export from Land Use of the George Town Conurbation Catchment

Zullyadini A. Rahaman, Mohamad Adam Omar, Narimah Samat, and Mohd Amirul Mahamud

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: geographic information system; land demand; land use; universal soil loss erosion

Online: 12 August 2020 (05:09:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201607.0008.v1

Spectral and Polarization Signatures of Relativistic Shocks in Blazars

Markus Boettcher

Subject: Physical Sciences, Astronomy And Astrophysics Keywords: active galaxies; blazars; jets; polarization; shock acceleration

Online: 8 July 2016 (03:03:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0512.v1

Evidence On Viral Suppression Supports Scaling-Up Transition To Dolutegravir-Based Regimens In Pediatric Populations In Cameroon: A Multicentre Baseline Assessment For The Cipher-Adola Study

Joseph FOKAM, Yagai Bouba, Rogers Awoh Ajeh, Dominik Tameza Guebiapsi, Suzane Essamba, Albert Franck Zeh Meka, Ebiama Lifanda, Rose Armelle Ada, Yakouba Liman, Nancy Barbara Mbengono, Audrey Raissa Dzaddi Djomo, Suzie Ndiang Tetang, Samuel Martin Sosso, Jocelyne Carmen Babodo, Olivia Francette Ndomo Ambomo, Edith Michele Temgoua, Caroline Medouane, Sabine Ndejo Atsinkou, Justin Leonel Mvogo, Roger Martin Onana, Jean de Dieu Anoubissi, Alice Ketchaji, Alex Durand Nka, Davy-Hyacinthe Anguechia Gouissi, Aude Christelle Ka’e, Nadine Nguendjoung Fainguem, Rachel Simo Kamgaing, Désiré Augustin Komego Takou, Michel Carlos Tommo Tchouaket, Ezechiel Ngoufack Jagni Semengue, Marie Atsama Amougou, Julius Nwobegahay, Comfort Vuchas, Anna Nya Nsimen, Bertrand Bille Eyoum, Sandra kenmegne Gatchuessi, Francis Ndongo Ateba, Daniel Kesseng, Serge Clotaire Billong, Daniele Armenia, Maria Mercedes Santoro, Francesca Ceccherini-Silberstein, Paul Ndombo Koki, Hadja Cherif Hamsatou, Vittorio Colizzi, Alexis Ndjolo, Carlo Federico Perno, Anne-Cécile Zoung-Kanyi Bissek

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Virological suppression; low level viremia; children, adolescents, and young-adults; DTG-based regimen; elimination of paediatric AIDS; Cameroon.

Online: 5 July 2024 (12:31:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1485.v1

Powders Synthesized from Calcium Carbonate and Water Solutions of Potassium Hydrosulfate of Various Concentrations

Tatiana V. Safronova, Peter D. Laptin, Alexandra I. Zybina, Xiaoling Liao, Tatiana B. Shatalova, Olga V. Boytsova, Dinara R. Khayrutdinova, Marat M. Akhmedov, Zichen Xu, Muslim R. Akhmedov

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: potassium hydrosulfate; calcium carbonate; heterophase synthesis; syngenite; gypsum; arcanite

Online: 22 August 2024 (03:10:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.2582.v1

Investigation of Mutations in the crt-o and mdr1 Genes of Plasmodium vivax for the Molecular Surveillance of Chloroquine Resistance in Parasites from Gold Mining Areas in Roraima, Brazil

Jacqueline de Aguiar-Barros, Fabiana Granja, Rebecca de Abreu-Fernandes, Lucas Tavares de Queiroz, Daniel da Silva e Silva, Arthur Camurça Citó, Natália Ketrin Almeida-de-Oliveira Mocelin, Cláudio Tadeu Daniel-Ribeiro, Maria de Fátima Ferreira-da-Cruz

Subject: Medicine And Pharmacology, Tropical Medicine Keywords: Amazon; malaria; chloroquine; pvcrt-o; pvmdr1; mining

Online: 2 August 2024 (11:45:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1524.v1

Global Dynamics of Environmental Kuznets Curve: A Cross-Correlation Analysis of Income and CO2 Emissions

Dora Almeida, Luísa Carvalho, Paulo Ferreira, Andreia Dionísio, Inzamam Ul Haq

Subject: Business, Economics And Management, Economics Keywords: Environmental Kuznets curve; CO2 emissions; Economic growth; Cross-correlation analysis; Income levels; Sustainable development

Online: 19 July 2024 (06:35:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1472.v1

Association between the intake/type of cheese and cognitive function in community-dwelling older women in Japan: A cross-sectional study

Takao Suzuki, Yosuke Osuka, Narumi Kojima, Hiroyuki Sasai, Kentaro Nakamura, Chisato Oba, Mayuki Sasaki, and Hunkyung Kim

Subject: Biology And Life Sciences, Aging Keywords: Cheese intake; Camembert cheese; MMSE score; Mild cognitive decline; Community-dwelling older women

Online: 18 July 2024 (08:39:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0432.v1

Interleukin-4 (IL-4), Plasminogen Activator Inhibitor-1 (PAI-1) or Receptor for Advanced Glycation End-Products (RAGE) in Bronchial Secretions Cannot Predict Pediatric Ventilator-Associated Pneumonia (VAP)

Argyro Ftergioti, Maria Simitsopoulou, Maria Sdougka, Styliani-Antonia Kallou, Anna-Bettina Haidich, Christina Virgiliou, Georgios Theodoridis, Emmanuel Roilides, Elias Iosifidis

Subject: Medicine And Pharmacology, Internal Medicine Keywords: ventilator-associated pneumonia; biomarkers; pediatric intensive care unit; critically-ill children; ventilator-associated pneumonia; biomarkers; pediatric intensive care unit; critically-ill children

Online: 4 July 2024 (11:00:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0230.v1

Definition of a Multi-omics Signature for Esophageal Adenocarcinoma Prognosis Prediction

Luca Lambroia, Carola Conca Dioguardi, Simone Puccio, Andrea Pansa, Giorgia Alvisi, Gianluca Basso, Javier Cibella, Federico S. Colombo, Salvatore Marano, Silvia Basato, Rita Alfieri, Simone Giudici, Carlo Castoro, Clelia Peano

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: Esophageal-Adenocarcinoma; Cancer; immunotherapy; treatment; single-cell RNA; single-cell sequencing; RNA sequencing; transcriptional signature; response to therapy; immune infiltrate.

Online: 3 July 2024 (00:25:13 CEST)

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Preprint REVIEW | doi:10.20944/preprints202407.0190.v1

Senescence in Adipose-Derived Stem Cells: Biological Mechanisms and Therapeutic Challenges

Riccardo Foti, Gabriele Storti, Marco Palmesano, Maria Giovanna Scioli, Elena Fiorelli, Sonia Terriaca, Giulio Cervelli, Bong Sung Kim, Augusto Orlandi, Valerio Cervelli

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: adipose-derived stem cells; mesenchymal stem cells; ageing; senescence; stem cell therapy; senescence; diabetes; senolytic drugs

Online: 2 July 2024 (10:24:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1553.v1

CO2-Breathing Prior to Simulated Diving Increases Decompression Sickness Risk in a Mouse Model: The Microbiota Trail Is Not Forgotten

Lucille Daubresse, Aurélie Portas, Alexandrine Bertaud, Marion Marlinge, Sandrine Gaillard, Jean-Jacques Risso, Céline Ramdani, Jean-Claude Rostain, Nabil Adjiriou, Anne-Virginie Desruelle, Jean-Eric Blatteau, Régis Guieu, Nicolas Vallée

Subject: Biology And Life Sciences, Other Keywords: Bubble formation; Dysbiosis; Auto-immune; Auto-inflammation; Akkermansia; Rhizobium; Gut-Brain axis; Hypercapnia

Online: 21 June 2024 (16:40:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0185.v1

Structural Outcomes of Corneal Cross-Linking for Keratoconus

Yauhen Statsenko, Darya Smetanina, Roman Voitetskii, Gillian Lylian Simiyu, Mikalai Pazniak, Elena Likhorad, Aleh Pazniak, Pavel Beliakouski, Dmitriy Abelskyi, Klaus N.-V. Gorkom, Milos Ljubisavljevic

Subject: Medicine And Pharmacology, Ophthalmology Keywords: keratoconus; corneal collagen cross-linking; CXL outcomes; machine learning models; predictive models; keratometry readings; corneal thickness; corneal thinning; individualized approach; precision medicine

Online: 5 June 2024 (05:54:59 CEST)

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Preprint REVIEW | doi:10.20944/preprints202403.1776.v1

Oceanographic Research in Thermaikos Gulf: A Review over Five Decades

Yannis Androulidakis, Christos Makris, Katerina Kombiadou, Yannis N. Krestenitis, Natassa Stefanidou, Chryssanthi Antoniadou, Evangelia Krasakopoulou, Maria-Ignatia Kalatzi, Vasilis Baltikas, Maria Moustaka-Gouni, Chariton Charles Chintiroglou

Subject: Environmental And Earth Sciences, Oceanography Keywords: Aegean Sea; Mediterranean; physical processes; marine pollution; sediment transport; biological processes; monitoring

Online: 28 March 2024 (14:28:03 CET)

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Thermaikos Gulf (TG) is a semi-enclosed, river-influenced, marine system situated in the eastern Mediterranean Sea, sustaining both urban coastal regions and ecologically preserved natural areas. Facing a plethora of environmental and anthropogenic pressures, the TG serves as a critical nexus where human activities intersect with marine ecosystems. The second largest city of Greece, Thessaloniki, is located in the northern part of the gulf, while a large environmentally protected zone with multiple river deltas is lying along its western coasts. The quality and health of the TG’s marine environment are tightly linked to the socioeconomic activities of the coastal communities comprising approximately 1.5 million inhabitants. The main features of TG’s environmental dynamics and ecological status have been scrutinized by dedicated research endeavours during the last 50 years. This review synthesizes the seminal findings of these investigations, offering an evaluation of their contribution to research, their present collective impact, and their trajectory toward the future. A severe deterioration of the TG’s environmental quality was detected in the 1970s and 1980s when treatment of urban wastewater was completely absent. A steady trend of recovery was observed after the 1990s, however without achieving, so far, the goal of a “good environmental state”, mandated by national legislation and European directives. The most important research gaps and uncertainties are also discussed and specific recommendations for the improvement of monitoring and understanding about the physical, biochemical, and ecological state of the gulf are provided. The most significant discrepancy is related to the fragmentary monitoring of the TG in both space (partial coverage) and time (temporal gaps), which has been intensified after 2010 due to the reduced funding for environmental research and protection under the severe Greek economic recession. This review aspires to highlight the importance of bolstering monitoring initiatives that can provide continuous observations and further understanding on the TG's ecological and physicochemical conditions. Targeted recommendations, aimed at ameliorating the fragmented monitoring processes, are also provided, advocating for a holistic approach that can safeguard the ecological integrity of the Thermaikos Gulf and uphold its role as a crucial link to marine biodiversity and sustainability in the Mediterranean basin.

Preprint ARTICLE | doi:10.20944/preprints202403.0958.v1

Comparison of the HBSC Results of the Visegrad Countries with the Health Behavior of Young People with Disabilities Living in Hungary: A Cross-Sectional Study

Agota Barabas, Attila Csaba Nagy, Viktoria Pazmany, Anita Katalin Grestyak Molnarne, Nemeth Agnes, György Jona, Agnes Santha, Peter Takacs, Emil Toldy, Renata Javorne Erdei

Subject: Public Health And Healthcare, Other Keywords: health; health behavior; disability; Visegrad Group

Online: 18 March 2024 (09:10:06 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0669.v1

Assessment of Postbiotic, Mundticin-like Substance EM 41/3 Application in Broiler Rabbits

Andrea Lauková, Ľubica Chrastinová, Valentína Focková, Iveta Plachá, Eva Bino, Ľubomira Grešáková, Zuzana Formelová, Rudolf Žitňan, Grzegorz Belzecki, Renata Miltko, Monika Pogány Simonová

Subject: Biology And Life Sciences, Life Sciences Keywords: bacteriocin; broiler rabbits; postbiotic effect; health status

Online: 12 March 2024 (13:44:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0477.v1

Body Awareness as a Protective Factor against Suicidal Orientations in College Students

Olga Lucía Montoya-Hurtado, Renato Sobral Monteiro-Junior, Cyndi Yacira Meneses-Castaño, Consuelo Sancho Sanchez, Antonio Martínez-Sabater, Maria Pilar Andrés-Olivera, Pilar Sánchez-Conde, Jesús Pérez, José Maria Criado-Gutierrez, Laura Criado-Pérez, Juan Luis Sanchez-González, Raúl Juárez-Vela

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: body awareness; interoception; suicide prevention; attempted suicide

Online: 8 March 2024 (11:18:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.1253.v1

Antiviral Effect of Antimicrobial Peptoids and a Murine Model of Respiratory Coronavirus Infection

Maxim Lebedev, Aaron Benjamin, Sathish Kumar, Natalia Molchanova, Jennifer S. Lin, Kent J. Koster, Julian L. Leibowitz, Annelise E. Barron, Jeffrey D. Cirillo

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Peptoid; MHV; SARS-CoV-2; Antimicrobials

Online: 22 February 2024 (09:24:34 CET)

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Preprint ARTICLE | doi:10.20944/preprints201609.0056.v1

The Impacts of Different Green Manure on Soil Microbial Communities and Crop Health

Hongwu Yang, Jiaojiao Niu, Jiemeng Tao, Yabing Gu, Chao Zhang, Siyuan She, Wu Chen, Hongqi Yang, Huaqun Yin

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: green manure; soil microbial communities; crop health; Illumina sequencing

Online: 18 September 2016 (08:56:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201608.0040.v1

Prevalence, Characterization and Mycotoxin Production Ability of Fusarium species on Korean Adlay (Coix lacrymal-jobi L.) Seeds

Tae Jin An, Kyu Seop Shin, Narayan Chandra Paul, Young Guk Kim, Seon Woo Cha, Yu Seok Moon, Seung Hun Yu, Sang-Keun Oh

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: seeds; ELISA; Fusarium; morphological data analysis; mycotoxins; phylogenetic analysis S

Online: 4 August 2016 (10:12:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0220.v1

A Cross-Sectional Study of Pre-prepared Foods Knowledge, Attitudes and Practices of College Students in Central China

Reyisaimu Wumaierjiang, Yijia Xu, Lei Wang, Taotao Guo, Guoxun Chen, Rui Li

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: knowledge; attitude; practice; pre-prepared foods; Chinese college students

Online: 4 September 2024 (03:08:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1348.v1

Infections in Children with Acute Lymphoblastic Leukemia

Silvije Šegulja, Klara Vranešević, Ana Đorđević, Jelena Roganović

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: acute lymphoblastic leukemia; child; infection; neutropenia

Online: 20 August 2024 (03:39:12 CEST)

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Preprint REVIEW | doi:10.20944/preprints202408.1350.v1

Atrial Fibrillation in Elite Athletes: A Comprehensive Review of Literature

Christos Kourek, Alexandros Briasoulis, Elias Tsougos, Ioannis Paraskevaidis

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: atrial fibrillation; elite athletes; pathophysiology; management

Online: 20 August 2024 (03:16:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1116.v1

An Extreme Learning Machine Stock Price Prediction Algorithm Based on the Optimisation of the Crown Porcupine Optimisation Algorithm with an Adaptive Bandwidth Kernel Function Density Estimation Algorithm

Keke Yu, Qiaozhi Bao, Haosen Xu, Guanghe Cao, Siwei Xia

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Extreme learning machine; Crown porcupine optimisation algorithm; Adaptive bandwidth kernel function density estimation algorithm

Online: 15 August 2024 (22:47:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1114.v1

Performance of the Multi-Class Classification Tools for Small Samples of Lamiaceae Family Herb Species

Kamila Kucharska-Ambrożej, Joanna Karpińska, Artur Ratkiewicz

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: Keywords: UV-Vis, ATR-FTIR, multiclass discriminative analysis, class oriented methods, SIMCA

Online: 15 August 2024 (08:51:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0387.v1

Coastal Sea Ice Concentration Derived from Marine Radar Images: A Case Study from Utqiaġvik, Alaska

Félix St-Denis, Bruno Louis Tremblay, Andrew R. Mahoney, Pacifica Askitrea Leona Mai Takata-Glushkoff

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: Coastal Radar; Sea Ice Concentration; Remote sensing; Utqiaġvik; Arctic

Online: 6 August 2024 (06:20:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0342.v1

1,2-Dicinnamoyl-Sn-Glycero-3-Phosphocholine Enhances Insulin Sensitivity and Increases the Expression Level of mtDNA-Encoded Genes in Insulin-Resistant 3T3-L1 Adipocytes – a Preliminary Study

Aneta Cierzniak, Anna Gliszczyńska, Małgorzata Małodobra-Mazur

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: insulin resistance; cinnamic acid; phospholipid derivative; phenolic acid; 1,2-di-CA-PC

Online: 5 August 2024 (13:46:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1933.v1

Selected Physical and Mechanical Properties of Particleboards Manufactured from Plantation Willow and Poplar Wood

Bartłomiej Żabowski, Anita Wronka, Grzegorz Kowaluk

Subject: Biology And Life Sciences, Forestry Keywords: particleboard; willow; poplar; alternative lignocellulosic material; biomass

Online: 24 July 2024 (10:45:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1740.v1

Marijuana Use and Associated Risk Behavior Factors among High School Students in Mississippi: Youth Risk Behavior Surveillance System 2021

Amal K. Mitra, Zhen Zhang, Julie A. Schroeder

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: marijuana; risk behavior; drug use; suicidality; CDC; YRBS

Online: 23 July 2024 (07:12:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1507.v1

Integrating IoT for Soil Monitoring and Hybrid Machine Learning in Predicting Tomato Crop Diseases in a Typical South India Station

Gurujukota Ramesh Babu, M. Gokuldhev, P. S. Brahmanandam

Subject: Computer Science And Mathematics, Computer Science Keywords: IoT; soil monitoring; ML algorithms; tomato crop disease prediction, soil parameter analysis; precision agriculture

Online: 19 July 2024 (02:51:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1430.v1

Genetic Diversity, Virulence, and Antibiotic Resistance Determinants of Campylobacter jejuni Isolates in Romania

Madalina Baltoiu, Gratiela Gradisteanu Pircalabioru, Dana Cristea, Marinela Sorokin, Ileana Stoica

Subject: Biology And Life Sciences, Insect Science Keywords: Campylobacter; C. jejuni; virulence; antibiotic resistance

Online: 17 July 2024 (12:34:55 CEST)

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Preprint REVIEW | doi:10.20944/preprints202407.1005.v2

Weight-Bearing CT for Diseases around the Ankle Joint

Jahyung Kim, Jaeyoung Kim, Saintpee Kim, Young Yi

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: Weight-bearing; CT; ankle arthritis; syndesmosis injury; osteochondral lesion of talus; ankle instability

Online: 15 July 2024 (04:52:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1035.v1

The Hydroxyapatite-Filled Acrylonitrile-Butadiene Rubber Composites with Improved Cure Characteristics and Reduced Flammability

Magdalena Maciejewska, Przemysław Rybiński, Anna Sowińska-Baranowska

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: acrylonitrile-butadiene rubber; hydroxyapatite; filler; flammability; silane; ionic liquid; surfactant; vulcanization; dispersibility

Online: 12 July 2024 (12:08:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0784.v1

A Review of Pakistan's National Spatial Data Infrastructure Using Multiple Assessment Frameworks

Munir Ahmad, Asmat Ali, Muhammad Nawaz, Farha Sattar, Hammad Hussain

Subject: Environmental And Earth Sciences, Other Keywords: Pakistan; NSDI; Sustainable Development; SDI; SDI Readiness Index

Online: 10 July 2024 (14:03:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1815.v1

Robotic Seeding of Large Porous Scaffolds

Gilad Gome, Julian Waksberg, Oded Shoseyov

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Scaffolds; Seeding; Automatic; Liquid dispensing

Online: 26 June 2024 (10:08:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1532.v1

Identifying Habitat Productivity Thresholds to Assess the Effects of Drought on a Specialist Folivore

Ivan Kotzur, Ben D Moore, Chris Meakin, Maldwyn J Evans, Kara N Youngentob

Subject: Biology And Life Sciences, Ecology, Evolution, Behavior And Systematics Keywords: NDVI; koala; herbivore; remote sensing; forest; Landsat; drought; habitat

Online: 21 June 2024 (16:56:28 CEST)

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Climate change has altered the frequency and severity of extreme weather, which can affect vegetation condition and habitat quality for wildlife. Declines in vegetation productivity during droughts and heatwaves can negatively impact animals that depend on vegetation for water and nutrition. The ability to detect such effects on habitat suitability can reveal refugia, which can be prioritised for protection to improve threatened species conservation. We used the normalised difference vegetation index (NDVI) to look at relationships between vegetation productivity and the presence of koalas (Phascolarctos cinereus) in potential habitat throughout much of their range. Using a large, long-term koala presence dataset, we tested the hypothesis that locations where koalas had been observed would exhibit higher NDVI values than a random, representative sample from the same vegetation group (i.e. woodlands, open forests or tall open forests). We also identified the minimum NDVI threshold at which koalas occurred across time for each vegetation group and compared these to the minimum NDVI values observed across potential koala habitat before and during the millennium drought; one of the worst recorded in Australia. Additionally, we investigated whether vegetation above the minimum NDVI thresholds was significantly closer to perennial water than unsuitable vegetation. We found that koalas tend to occur at locations exhibiting higher NDVI than average for all vegetation groups. We also found that 49% of all vegetation groups maintained a minimum NDVI above the koalas’ NDVI threshold before drought, equating to 190,227 km2, which declined to 166,746 km2 during drought (a 12% reduction). We also found that unsuitable vegetation tended to occur farther from perennial water than suitable vegetation for some vegetation groups. Areas that remained above the NDVI thresholds during the drought should be considered potential refugia for populations during an event of similar magnitude and could indicate future core habitat extent.

Preprint ARTICLE | doi:10.20944/preprints202406.1439.v1

Applying and Improving Pyranometric Method to Estimate Sunshine Duration for a Tropical Site

Tovondahiniriko Fanjirindratovo, Didier Calogine, Oanh Chau, Olga Ramiarinjanahary

Subject: Physical Sciences, Other Keywords: Carpentras method; data fitting; global radiation; sunshine duration; Slob and Monna algorithm; step algorithm; linear algorithm

Online: 21 June 2024 (05:37:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1018.v1

Effects of Bosentan on Hypoxia, Inflammation and Oxidative Stress in Experimental Blunt Thoracic Trauma Model

Nedim Uzun, Sinem Durmuş, Gonca Gercel, Burhan Aksu, Naile Fevziye MISIRLIOGLU, Hafize Uzun

Subject: Medicine And Pharmacology, Emergency Medicine Keywords: Pulmonary contusion; endothelin-1; ET-1; hypoxia-inducible factor-1 HIF-1; nuclear factor-kappa B; tumor necrosis factor-α pro-oxidant antioxidant balance; lung tissue

Online: 14 June 2024 (11:27:55 CEST)

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Backround: Thoracic trauma causes life-threatening organ injuries, ranging from simple abrasions to contusions of intrathoracic organs. In this study, we aimed to investigate the effects of bosentan on endothelin-1 (ET-1), hypoxia-inducible factor-1 (HIF-1), nuclear factor-kappa B (NF-κB), tumor necrosis factor (TNF)-α as inflammation markers, pro-oxidant antioxidant balance (PAB) and total antioxidant capacity (TAC) levels as oxidative stress parameters in lung tissues of rats in experimental model of pulmonary contusion (PC) induced by blunt thoracic trauma. Methods: Thirty-seven animals male Sprague-Dawley rats were divided into 5 groups. All 4 groups, except for the control group, were performed to PC. In the first group, C: control group (n=6) consisted of unprocessed and untreated. The second group, PC3 (n=8) underwent of 3 days PC performed. The third group, PC-B3 (n=8) received 100 mg/kg bosentan was given orally once a day for 3 days. The fourth group, PC7 group (n=7) underwent of 7 days PC performed, and the fifth group PC-B7 (n=8) received 100 mg/kg bosentan was given orally once a day for 7 days. While ET-1, NF-B, TNF-, and HIF-1 was measured by ELISA method, TAC and PAB by spectrophotometric in lung tissue samples. Results: ET-1, NF-B, TNF-, HIF-1, and PAB levels were higher, while TAC activities were lower in all groups compared with the control (p < 0.05). There was no significant difference in ET-1 and TNF-- levels between the PC-B3 and PC-B7 groups and the control group (p < 0.05) while NF-B, HIF-1, and PAB levels were still higher in both the PC-B3 and PC-B7 groups than in the control group. Bosentan treatment causes decreased ET-1, NF-B, TNF-, HIF-1, and PAB and increased TAC levels in comparison to the nontreated groups (p < 0.05). Conclusions: We found that the use of bosentan decreased the severity of oxidative stress in the lung and reduced the inflammatory reaction in rats with PC induced by blunt thoracic trauma. This suggests that bosentan may have protective effects on lung injury mechanisms by reducing hypoxia, inflammation and oxidative stress. If supported by similar studies, bosentan can be used in both pulmonary and emergency clinics to reduce ischemic complications, inflammation, oxidative stress in some diseases that may be accompanied by ischemia.

Preprint ARTICLE | doi:10.20944/preprints202406.0765.v1

Probing Biological Nitrogen Fixation in Legumes Using Raman Spectroscopy

Abdolabbas Jafari, Kritarth Seth, Armin Werner, Shengjing Shi, Rainer Hofmann, Valerio Hoyos-Villegas

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Pattern recognition; chemometrics; precision agriculture; non-destructive; rhizobia; symbiosis

Online: 12 June 2024 (11:58:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0737.v1

Calculation of Restoring and Repulsive Magnetic Forces between two Non-coaxial Coils of Rectangular Cross-Section with Parallel Axes

Slobodan Babic, Eray Guven, Kai-Hong Song, Yao Luo

Subject: Engineering, Electrical And Electronic Engineering Keywords: Mutual inductance; restoring force; repulsive force; coils of rectangular cross-section with parallel axes

Online: 11 June 2024 (18:20:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0163.v1

Study on Key Properties and Model Establishment of Innovative Recycled Aggregate Pervious Concrete

Panfeng Zhao, Jingfei Zhou, Zhengnan Zhang, Shoukai Chen

Subject: Engineering, Architecture, Building And Construction Keywords: Innovative recycled aggregate pervious concrete; Response surface methodology; Compressive strength; Permeability coefficient; Acrylic pipe

Online: 4 June 2024 (16:14:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1934.v1

A Comprehensive Analysis of Knowledge Sharing, Training, Communication, and Attitudes for Effective Medical Waste Management among Healthcare Providers in Bangladesh

Armanul Haque, Ikbal Hossain, Rebeka Sultana Rekha, Amitav Saha, Ayrin Chowdhury, Bashir Uddin, Ritu Rani Baiday

Subject: Social Sciences, Library And Information Sciences Keywords: Knowledge sharing; Attitude; Communication; Training; Practice; Effective medical waste management

Online: 29 May 2024 (08:25:38 CEST)

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Medical waste management is crucial issues for keeping our life safe and safety. Without effective measures for waste management, we cannot keep ourselves safe from different types of contagious diseases; viruses, bacteria. Knowledge sharing assists healthcare staff in identifying and mitigating hazards on appropriate handling, segregation and disposal medical waste. The aim of the study is to identify a multifaceted analysis of knowledge sharing, training, communication and attitudes for effective medical waste management. This study selected 153 medical workers randomly, including nurses, lab technologists, and cleaners, from hospitals, diagnostic centers, and clinics in the northern part of Bangladesh. The study design of this research is mixed-methods. This research adopts a survey and interview as a research strategy. The samples are collected randomly. SPSS software packages, MS Excel Office, and PLS-SEM are used to analyze data. Most of the respondents always share their knowledge face-to-face according to the findings. The result also shows that there are positive relationship between sources of knowledge (p: 0.046), awareness and knowledge (p: 0.049), attitudes of waste management (p: 0.025) and effective medical waste management. However, there are no relationships between communication and collaboration (p: 0.943), the practice of waste management (p: 0.155), supervision and staff monitoring (p: 0.527), training and education (p: 0.656) and effective medical waste management. Its focus on the northern part of Bangladesh introduces regional specificity, potentially limiting the applicability of results to other regions. The knowledge-sharing practices for waste management among medical staff are examined within this research, along with the relationship between attitude, awareness, and knowledge, staff supervision and monitoring, practice, training, and education and effective medical waste management that have not been studied before home and abroad. This analysis highlights the critical need for an integrated approach to medical waste management, emphasizing the importance of continuous education, open communication, and cultivating a culture that prioritizes environmental sustainability. The insights from this study offer practical recommendations for healthcare institutions to improve their medical waste management practices, ultimately leading to enhanced health outcomes and better environmental protection.

Preprint REVIEW | doi:10.20944/preprints202405.1859.v1

Iron Oxide Nanoparticles as Photothermal Agents: Optimal Parameters for Photoconversion Efficiency and Ability for Synergistic Cancer Treatment

Tsenka Grancharova, Plamen Zagorchev, Bissera Pilicheva

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: iron oxide; photothermia; theranostic; synergistic; cancer; nanomedicine; nanoparticles

Online: 28 May 2024 (12:05:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1342.v1

Making the Research and Innovation Ethical: A Conceptual Framework for Ethics Assessment of Nanotechnology Innovations

Skanthesh Lakshmanan, Vinayak Padikkal Varyam, Oriparambil Sivaraman Nirmal Ghosh

Subject: Social Sciences, Other Keywords: nanoethics; technology assessment; ethical space; mycotoxin

Online: 21 May 2024 (04:59:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0934.v1

In Vitro Hemostatic Activity of Novel Fish Gelatin- Alginate Sponge (FGAS) Prototype

Heri Herliana, Harmas Yazid Yusuf, Avi Laviana, Ganesha Wandawa, Basril Abbas

Subject: Medicine And Pharmacology, Dentistry And Oral Surgery Keywords: Fish gelatin; alginate; hemostatic sponge; blood coagulation

Online: 14 May 2024 (09:31:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0761.v1

The ‘Radiant Effect’: Recent Sonographic Image-Enhancing Technique and Its Impact on Nuchal Translucency Measurements

Arne Bergsch, Jan Degenhardt, Rüdiger Stressig, Heiko Dudwiesus, Oliver Graupner, Jochen Ritgen

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: Nuchal Translucency; First Trimester Screening; Image Enhancement; Aneuploidies; Prenatal Diagnostics

Online: 13 May 2024 (12:15:17 CEST)

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Preprint REVIEW | doi:10.20944/preprints202405.0532.v1

Application of additive manufacturing in automobile industry: a mini review

Jian Yang, Bo Li, Jian Liu, Zhantong Tu, Xin Wu

Subject: Engineering, Automotive Engineering Keywords: additive manufacturing; automobile industry; printable materials; product quality

Online: 9 May 2024 (12:09:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0401.v1

Definition of the Sensory and Aesthetic Spaces of Dry White Wines with Aging Ability by Experienced Tasters

Marta Esteves, Mariana Sequeira, Manuel Malfeito Ferreira

Subject: Biology And Life Sciences, Food Science And Technology Keywords: white wines, fine wines, aging potential, appreciation, age prediction, browning, complexity, quality.

Online: 7 May 2024 (13:52:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0061.v1

Past and Future Impacts of the Relative Sea Level Rise on the Seafront of Ancient Delos (Cyclades, Greece) and Flooding Scenarios by 2150

Nikos Mourtzas, Eleni Kolaiti

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: ancient Delos; Cyclades; Aegean; Greece; past sea level changes; ancient sea defences; sea level projections; vertical land motion; flooding scenarios up to 2150; mitigation and adaptation measures

Online: 1 May 2024 (07:53:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1793.v1

Challenges for Compliance with Industrial Effluent Regulations – the Industry Perspective

Zulaikha Mokhtar, Steven Kenway, Ilje Pikaar, Irdayanti Mat Nashir

Subject: Environmental And Earth Sciences, Other Keywords: Industry challenge; environmental compliance; continuous improvement; behavioral change; adaption of regulation

Online: 28 April 2024 (07:49:05 CEST)

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Preprint REVIEW | doi:10.20944/preprints202404.1695.v1

Relationship Between Parenting Educational Styles and Well-Being in Families with Autistic Children. A Systematic Review

Elena Benseny Delgado, Wenceslao Peñate Castro, Alicia Diaz Megolla

Subject: Social Sciences, Psychology Keywords: Autism spectrum disorder; parenting styles; family well-being; quality of life; satisfaction with the parental role

Online: 26 April 2024 (07:43:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1654.v1

VIMPS: Physics-Based Spatiotemporal Indicator for Proactive Humping Detection in Metal Additive Manufacturing

Mohamed Abubakr Hassan, Mahmoud Hassan, Chi-Guhn Lee, Ahmad Sadek

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: monitoring; additive manufacturing; direct energy deposition; proactive; solidification front; spatiotemporal

Online: 25 April 2024 (10:11:06 CEST)

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Preprint REVIEW | doi:10.20944/preprints202404.1414.v1

The Veterinarian’s Role in Biocontainment Research Animal Facilities and Prevention of Spread of Pathogens in Africa

John Kudakwashe Chipangura, Abdussamad M. Abdussamad, David I. Lewis

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: Veterinarian; Biocontainment research animal facility; Epicentre; Pathogens; Contamination

Online: 22 April 2024 (14:02:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0929.v1

Substitution of Inorganic Fertilizers with Organic Fertilizers Influences Soil Carbon and Nitrogen Content and Enzyme Activity under Rubber Plantation

Qiu Yang, Jiale Li, Wenxian Xu, Jingjing Wang, Yamin Jiang, Waqar Ali, Wenjie Liu

Subject: Environmental And Earth Sciences, Ecology Keywords: Organic fertilizers substitution; soil fertility; soil carbon; nitrogen; soil enzymes; rubber plant.

Online: 15 April 2024 (18:06:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0771.v1

Decoupling Interaction for CFD-DEM Simulations of Bubbling Fluidized Bed

Yanggui Li, Heping Wang, Guorong Wu

Subject: Engineering, Chemical Engineering Keywords: multiphase flow; fluidization; simulation; CFD-DEM

Online: 11 April 2024 (09:26:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0329.v1

Redundant Space Manipulator Autonomous Guidance for In-Orbit Servicing via Deep Reinforcement Learning

Matteo D’Ambrosio, Lorenzo Capra, Andrea Brandonisio, Stefano Silvestrini, Michèle Roberta Lavagna

Subject: Engineering, Aerospace Engineering Keywords: Deep Reinforcement Learning; 7-DoF space manipulator; motion synchronization; In-Orbit Servicing

Online: 4 April 2024 (17:28:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.1204.v2

Evaluation of the Phytochemical Profiles, Antioxidant and α-Glucosidase Inhibitory Activities of Four Herbal Teas Originating from China: A Comparative Analysis of Aqueous and Ethanol Extraction

Jin Zhang, Guodong Zhuang, Jinling Lv, Junjia Zhang, Feng Hu, Yongsheng Chen

Subject: Biology And Life Sciences, Food Science And Technology Keywords: herbal tea; phytochemicals; antioxidant; α-glucosidase

Online: 3 April 2024 (08:22:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1555.v1

A Laboratory Machine Verifying the Operation of a Hydraulic Rope Equalizer with Tensometric Sensors

Leopold Hrabovský, Jiří Fries, Štěpán Pravda

Subject: Engineering, Mechanical Engineering Keywords: tensometric sensor; rope equalizer; mining machine; traction elevator; breaking force; stranded rope

Online: 26 March 2024 (11:36:49 CET)

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In mining machines with friction discs, but also in multi-rope traction elevators, it is necessary to distribute the applied tensile load, generated by the weight of the cage and counterweight, evenly in all cross-sections of the load-bearing ropes. Hydraulic devices used for this purpose can operate on the principle of Pascal's law. The article presents a structural design, a 3D model and an implemented solution of a laboratory device capable of simulating a practical method of evenly distributing the total weight of the load into partial tensile forces of the same size acting on a selected number of load-bearing ropes. The laboratory equipment uses two pairs of three steel cables of finite length for the simulations. During the experimental measurements, tensile forces derived from the tractive force of the piston rods, pushed into the bodies of the hydraulic cylinders by the pressure of the hydraulic oil supplied through the pipeline under the pistons of the hydraulic cylinders, were detected. The resulting amount of hydraulic oil pressure in the hydraulic circuit influenced by different values of the hydraulic oil pressures in the hydraulic cylinders and by the pressure in the supply pipe was experimentally studied on the laboratory equipment. Simulations were also carried out in order to detect the hydraulic oil pressure in the hydraulic circuit caused by the change in the different magnitudes of the tensile forces in the ropes From the experiments carried out, it follows that with the appropriate choice of hydraulic elements and the design of the hydraulic circuit, the weight of the load, acting as the total pulling force in the ropes, can be evenly distributed (with a deviation of up to 5%) to all cross-sections of the load-bearing ropes. If the exact values of the hydraulic oil volumes under the pistons of all hydraulic cylinders are not known, it is not possible to calculate the pressure values in the hydraulic circuit when the valves of the hydraulic pipes are gradually opened.

Preprint ARTICLE | doi:10.20944/preprints202403.0727.v1

Oral Antiviral Defense: Saliva- and Beverage-Like Hypotonicity Dynamically Regulate Formation of Membraneless Biomolecular Condensates of Antiviral Human MxA in Oral Epithelial Cells

Pravin. B Sehgal, Huijuan Yuan, Anthony Centone, Susan V DiSenso-Browne

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: oral/gingival epithelium; environmental hypotonic stress; interferon-λ; human myxovirus re-sistance protein (MxA); biomolecular condensates; membraneless organelles (MLOs); osmoreg-ulation; macromolecular uncrowding and recrowding; regulated volume decrease (RVD)

Online: 12 March 2024 (15:23:39 CET)

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The oral mucosa represents a defense between the external environment and the rest of the body and encompasses several antimicrobial and antiviral mechanisms. Oral mucosal cells are constantly bathed in hypotonic saliva (normally one-third tonicity compared to plasma) and are repeatedly exposed to environmental stresses of tonicity, temperature and pH by the drinks we imbibe (e.g. hypotonic: water, tea, coffee; hypertonic: assorted fruit juices, red wines), as well as of diverse microbial and viral flora. In the mouth, the broad-spectrum antiviral mediator MxA (a dynamin-family large GTPase) is constitutively expressed in healthy periodontal tissues, and also induced by Type III interferons (e.g. IFN-λ1). Endogenously induced human MxA and exogenously expressed human GFP-MxA formed membraneless biomolecular condensates in the cytoplasm of oral carcinoma cells (OECM1 cell line). These condensates likely represent storage granules in equilibrium with antivirally active dispersed MxA. Remarkably, cytoplasmic MxA condensates were exquisitely sensitive sensors of hypotonicity – the condensates in oral epithelium disassembled within 1-2 min of exposure of cells to saliva-like one-third hypotonicity, and spontaneously reassembled in the next 4-7 min. OECM1 cells preloaded with calcein-AM (a reporter of cytosolic “macromolecular crowding”) confirmed unquenching and then requenching of calcein fluorescence during this process. Hypertonicity had little effect on MxA condensates. The spontaneous reassembly of GFP-MxA condensates in oral epithelial cells even under continuous saliva-like hypotonicity was slowed by the protein phosphatase inhibitor cyclosporin A (CsA) and by the K-channel blocker tetraethylammonium chloride (TEA) suggestive of the involvement of the volume-sensitive WNK kinase-protein phosphatase (PTP)-K-Cl cotransporter (KCC) pathway in the regulated volume decrease (RVD) during condensate reassembly in oral cells. Thus, physiologically, hypotonic drinks (water, tea, coffee) trigger a rapid deployment of antiviral MxA throughout the cytoplasm of oral epithelial cells, with subsequent salvage of MxA back into storage granules/condensates.

Preprint REVIEW | doi:10.20944/preprints202403.0362.v1

SARS-CoV-2 Vaccines-Related Endocrine Disorders: An Updated Narrative Review

Avraham Ishay, Kira Oleinikov, Elena Chertok Shacham

Subject: Medicine And Pharmacology, Endocrinology And Metabolism Keywords: COVID-19; COVID-19 vaccines; SARS-CoV-2 vaccine; endocrine adverse events; thyroid; pituitary; adrenal; diabetes; gonads

Online: 6 March 2024 (12:19:04 CET)

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Preprint ARTICLE | doi:10.20944/preprints201701.0069.v1

Environmental Impacts of Mining of Mineral Resources

Vladimír Lapčík, Andrea Kaločajová, Petr Novák

Subject: Environmental And Earth Sciences, Environmental Science Keywords: mining; non-energy mineral resources; environmental impact assessment

Online: 13 January 2017 (10:56:46 CET)

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Preprint ARTICLE | doi:10.20944/preprints201612.0030.v1

Modelling and Optimization in Microgrids

Tobias Porsinger, Przemyslaw Janik, Zbigniew Leonowicz, Radomir Gono

Subject: Engineering, Electrical And Electronic Engineering Keywords: microgrid; classification; simulation; optimization; renewable energy sources; storage; electric vehicles

Online: 6 December 2016 (07:52:50 CET)

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Preprint ARTICLE | doi:10.20944/preprints201609.0055.v1

Cultural Heritage Sites in Danger—Towards Automatic Damage Detection from Space

Daniele Cerra, Simon Plank, Vasiliki Lysandrou, Jiaojiao Tian

Subject: Arts And Humanities, Archaeology Keywords: change detection; Cultural Heritage; texture analysis

Online: 18 September 2016 (08:38:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201607.0063.v1

A study of controllability of impulsive neutral evolution integro-differential equations with state dependent delay in Banach space

Dimplekumar Chalishajar, A. Anguraj, Kulandhivel Karthikeyan, Malar Ganeshan

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: Impulsive conditions, Controllability, Neutral evolution integrodierential equa- tions, Resolvent operators, State dependent delay

Online: 21 July 2016 (03:48:42 CEST)

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Preprint REVIEW | doi:10.20944/preprints202409.0041.v1

Bilberry Encroachment in the Changing Subalpine Belt

Miroslav Zeidler, Marek Banaš

Subject: Environmental And Earth Sciences, Ecology Keywords: shrubification bilberry; Vaccinium myrtillus; subalpine; mountains; plant traits; habitat

Online: 2 September 2024 (11:36:03 CEST)

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Preprint REVIEW | doi:10.20944/preprints202402.1251.v3

Digital Image Correlation for Assessment of Bridges’ Technical State and Remaining Resource

Nadiia Kopiika, Yaroslav Blikharskyy

Subject: Engineering, Architecture, Building And Construction Keywords: DIC; bridges; monitoring; contactless; stress-strain state

Online: 26 August 2024 (15:23:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1448.v1

The Integration of Bio-Active Elements into Building Facades as a Sustainable Concept

Walaa Mohamed Metwally, Vitta Abdel Rehim Ibrahim

Subject: Environmental And Earth Sciences, Other Keywords: algae; bio-active; cultivation methods; environmental; sustainable approach

Online: 20 August 2024 (12:38:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1333.v1

The Extremal Trees for Logarithmic VDB Topological Indices

Zhenhua Su, Hanyuan Deng

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: tree; extreme value; logarithmic VDB topological indices

Online: 20 August 2024 (03:18:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1334.v1

New Spectrophotometric Visible (VIS) Analysis to determine Sodium Valproate from Tablets

CRISTIAN-CATALIN GAVAT

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: Sodium valproate; antiepileptic drug; spectrophotometric quantitative analysis method; light yellow azo dye; official declared pure amount; quantitative color reaction; statistical validation procedure

Online: 19 August 2024 (14:27:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0790.v1

Comparative Pharmacokinetics of 5 mg Sustained-Release Versus 5 mg Immediate-Release Melatonin Capsules in Fasting Healthy Adults: A Randomized, Open-Label, Cross-Over Study

Shefali Thanawala, R Abiraamasundari, Rajat Shah

Subject: Medicine And Pharmacology, Complementary And Alternative Medicine Keywords: Melatonin; pharmacokinetics; nutraceutical; sleep disorders; sustained-release

Online: 12 August 2024 (10:16:41 CEST)

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Preprint REVIEW | doi:10.20944/preprints202408.0638.v1

Environmental Sustainability in Hotels: A Review of the Relevance and Contributions of Assessment Tools and Techniques

Toshima Makoondlall-Chadee, Chandradeo Bokhoree

Subject: Environmental And Earth Sciences, Other Keywords: hotel sector; environmental sustainability; environmental sustainability assessment; assessment tools and techniques

Online: 9 August 2024 (10:13:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1722.v1

Economic Reforms and Consumption Trends: A Deep Dive into Saudi Arabia's Economic Evolution

Mwahib Mohammed

Subject: Business, Economics And Management, Economics Keywords: ; aggregate consumption; government spending; oil revenues; interest rates Saudi Arabia

Online: 22 July 2024 (12:26:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1989.v1

A Multimode Detection Platform for Biothiols Using BODIPY Dye-Conjugated Gold Nanoparticles

Panangattukara Prabhakaran Praveen Kumar

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: Biothiols; BODIPY; Gold nanoparticles; Raman spectroscopy

Online: 28 June 2024 (02:45:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1960.v1

GPU Accelerated Volume Renderer for Use with MATLAB

Raphael Scheible

Subject: Computer Science And Mathematics, Computer Vision And Graphics Keywords: Imaging, Three-Dimensional; Biomedical Image Processing; Medical Image Processing; Visualization; Direct Volume Rendering; GPGPU; 3D Image Analysis; Computer Graphics; MATLAB

Online: 27 June 2024 (18:47:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1440.v1

Effective Living Donor Evaluation in a Western Liver Transplantation Program

Oliver Rohland

Subject: Medicine And Pharmacology, Transplantation Keywords: living donor liver transplantation (LDLT), donor evaluation, donor selection criteria, deceased donor liver transplantation (DDLT) , liver transplantation (LT)

Online: 20 June 2024 (13:23:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0420.v1

Reservoir Routing and Its Application to Atmospheric Carbon Dioxide Balance

Demetris Koutsoyiannis

Subject: Environmental And Earth Sciences, Water Science And Technology Keywords: mass balance; continuity equation; reservoir routing; residence time; response time; carbon dioxide

Online: 8 May 2024 (00:24:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1313.v1

QKD Security Through Three-Dimensional Angular Momentum Representation

Guman Garayev, Azar Alili

Subject: Computer Science And Mathematics, Security Systems Keywords: quantum angular momentum; cryptography; machine learning

Online: 19 April 2024 (09:17:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0309.v1

Relative Importance of Carbon Dioxide and Water in the Greenhouse Effect: Does the Tail Wag the Dog?

Demetris Koutsoyiannis

Subject: Environmental And Earth Sciences, Other Keywords: greenhouse effect; longwave radiation; water vapour; carbon dioxide; evaporation

Online: 4 April 2024 (05:40:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202312.1928.v2

An Evolutionary Theory on Virus Mutation in COVID-19

Liaofu Luo, Jun Lv

Subject: Biology And Life Sciences, Ecology, Evolution, Behavior And Systematics Keywords: COVID-19; spike protein; virus mutation; evolutionary theory

Online: 26 March 2024 (11:33:54 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0804.v1

Detecting Reinforced Concrete Rebars Using Ground Penetrating Radars

Wael A. Zatar, Hien Nghiem, Hai Nguyen

Subject: Engineering, Civil Engineering Keywords: nondestructive evaluation; ground-penetrating radar (GPR); rebar depth; rebar diameter; reinforced-concrete structures

Online: 14 March 2024 (09:44:31 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.1667.v1

On Gohar Fractional Calculus

Abdelrahman Gohar, Mayada Younes, Salah Doma

Subject: Computer Science And Mathematics, Mathematics Keywords: ; Gohar fractional calculus; Gohar fractional Laplace transform; Gohar fractional power series expansion; Left and right Gohar fractional derivatives; Left and right Gohar fractional integrals ;

Online: 29 February 2024 (09:13:33 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.1035.v1

Shannon Holes, Black Holes and Knowledge: Can a Machine become a “Self-Aware" Teammate?

William Lawless ---, And Ira S. Moskowitz

Subject: Computer Science And Mathematics, Robotics Keywords: debate; knowledge; entropy; interdependence; human-machine teammates; autonomy; complexity; embodied cognition; information; vulnerability

Online: 19 February 2024 (14:31:26 CET)

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Preprint REVIEW | doi:10.20944/preprints202402.0877.v1

Investigating Barriers to Low-Carbon Policy Implementation among Mining Companies in Ghana

Seth Adom, Kenichi Matsui

Subject: Environmental And Earth Sciences, Sustainable Science And Technology Keywords: Mining companies; Carbon Emissions; Policy; Low-carbon Technology; Ghana

Online: 16 February 2024 (07:40:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.0333.v1

Efficacy of Floating-Dielectric Barrier Discharge Plasma against Staphylococcus aureus and Salmonella Typhimurium on Fried Fish Paste

So Hee Kim, Pantu Kumar Roy, Eun Bi Jeon, And Shin Young Park

Subject: Biology And Life Sciences, Food Science And Technology Keywords: fried fish paste; FE-DBD plasma; first-order kinetics; Staphylococcus aureus; Salmonella Typhimurium; Weibull model

Online: 6 February 2024 (05:24:13 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.0820.v1

Enterotoxins of EGC Cluster Prevalence in Staphylococcus aureus Collected from Clinical Samples of Paraguayan Children

Fátima Rodríguez A., Claudia Salinas D., Sergio Franco A., And Rosa Guillén F.

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Staphylococcus aureus; enterotoxin gene cluster (EGC); children

Online: 10 January 2024 (11:07:27 CET)

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