Induction motors are the most numerous and significant dynamic loads in power systems. In transient voltage stability analysis, dynamic equivalent models are commonly used to simplify the representation of a group of induction motors. This paper presents an method for the grouping and aggregation of induction motors at a common bus. Firstly, grouping rules were provided for clustering induction motors into several subgroups based on the mechanical principles of rotor force and motion, and Aggregation Rules were provided for aggregating a motor subgroup into a single-unit model based on the relationship between voltage drop and power transmission in distribution networks. Secondly, guided by the grouping rules, high-speed remaining electromagnetic torque and low-speed remaining electromagnetic torque were defined as new clustering indicators, and an adaptive K-means clustering method using silhouette coefficient verification was provided to obtain the optimal motor subgroups. Thirdly, guided by the Aggregation Rules, a dynamic equivalent method was further provided to obtain the equivalent single-unit model from a motor subgroup. Lastly, a transient voltage stability simulation in a typical distribution network was presented to illustrate that the proposed clustering and equivalent methods are more reasonable, accurate, and effective than traditional methods, as the obtained model has better dynamic characteristics and can more accurately reproduce the process of voltage collapse.

This paper is concerned about the novel exact solitons to the truncated M-fractional (1+1)-dimensional non-linear generalized Bretherton model with arbitrary constants . This model is used to explain the resonant nonlinear interaction between the waves in different phenomenon, including fluid dynamics, plasma physics, ocean waves, and many others. A series of exact solitons, including bright, dark, periodic, singular, singular-bright, singular-dark, and other solitons are obtained by applying the extended sinh-Gordon equation expansion (EShGEE), and the modified (G′/G2)-expansion tech- niques. A novel definition of Fractional derivative provides the solutions distinct from the present solutions. Mathematica software is used to obtain, and verify the solutions. The solutions are shown through 2-D, 3-D, and density plots. The stability process is performed to verify that the solutions are exact and accurate. The modulation instability is used to determine the steady-state stable results to the corresponding equation.

The success of near-infrared spectroscopy (NIRS) analysis hinges on the precision and robustness of the calibration model. Shallow learning (SL) algorithms like partial least squares discriminant analysis (PLS-DA) often fall short in capturing interrelationships between adjacent spectral variables, and the analysis results are easily affected by spectral noise, which dramatically limits the breadth and depth application of NIRS. Deep learning (DL) methods, with their capacity to discern intricate features from limited samples, are progressively integrated into NIRS. In this paper, two discriminant analysis problems including wheat kernels and Yali pears were used as examples, and several representative calibration models to research the robustness and effectiveness of the model. Additionally, this article proposed a near-infrared calibration model, which is based on gramian angular difference field and coordinate attention convolutional neural networks (G-CACNN). The research results show that, compared with SL, spectral preprocessing has a smaller impact on the analysis accuracy of consensus learning (CL) and DL, and the latter has the highest analysis accuracy in the modeling results of using the original spectrum. The accuracy of G-CACNN in two discrimination tasks is 98.48% and 99.39%, respectively. Finally, This research compared the performance of various models under noise to evaluate the robustness and noise resistance of the proposed method.

Property valuation services using artificial intelligence (AI) have been developed, with more than 20 services available in Japan. However, since their algorithms and training data are not publicly available, the extent of differences in the AI property valuations among these services is not clear. This study focuses on the five services handling a lot of properties and uses a sample of 4,295 property valuations for 859 condominium units in six popular residential areas in Tokyo. (1) Multiple comparison tests of the AI property valuations among each service are conducted to confirm their statistical significance and to examine the degree of the difference and variation. (2) The business models of each service are compared to examine the factors contributing to these differences and variations. The results showed that there was a variation of approximately 0.15 in the coefficient of variation between the high and low valuation groups, and the service providers in the high valuation group guided the users to their sales, while those in the low valuation group focused on attracting users as their business models. The contribution of this study is to indicate the possibility that the business models may lead to the differences in the AI property valuations.

When limited area models of the hydrodynamics of the atmosphere and of the ocean are 1 run over an extended time, variability unrelated to external "drivers" emerge - this variability is 2 colloquially named "hydrodynamical noise" or just "noise". This article summarises what we have 3 learned in the past few years about the properties of such noise, and the implications for numerical 4 experimentation and analysis. The presence of this noise can be identified easily in ensembles of 5 numerical simulations, and it turns out that the intensity of the noise is closely linked to the scale- 6 dependent "memory". At the system level, this "memory" term as given by Hasselmann’s Stochastic 7 Climate model plays a key role. In the case of marginal seas, the process of baroclinic instability 8 modulated by tides and the formation of seasonal thermoclines are significant aspects. Some more 9 general aspects are discussed, such as the applicability of the Stochastic Climate model to systems 10 outside of atmospheric and oceanic dynamics, the irreversibility of tipping points and the challenges 11 of detecting changes beyond a noise level and of the attribution of causes of change.

The repeated application of herbicides has led to the development of herbicide resistance. Models are useful for identifying key processes and understanding the evolution of resistance. This study developed a spatially explicit model at a landscape scale to examine the dynamics of Lolium rigidum populations in dryland cereal crops and the evolution of herbicide resistance under var-ious management strategies. Resistance evolved rapidly under repeated herbicide use, driven by weed fecundity and herbicide efficacy. Although fitness costs associated with resistant plants re-duced resistance evolution, they did not affect the speed of spread. The most effective strategies to slow resistance involved diversifying cropping sequences (e.g., crop rotation) and the herbicide applications (e.g., rotating different herbicide modes of action). Pollen flow was the main disper-sal vector, with seed dispersal also contributing significantly. Strategies limiting seed dispersal effectively decreased resistance spread. However, the use of a seed-catching device at harvest could unintentionally enrich resistance in the area. It would be beneficial to optimise the move-ment of harvesters between fields. The model presented here is a useful tool that may assist in the exploration of novel management strategies within the context of site-specific weed management at the landscape scale, as well as in the advancement of our understanding of resistance dynamics.

Evaluating the economic and environmental effects of farmers' green production behaviors holds important reference value for promoting sustainable agricultural development, alleviating agricultural non-point source (NPS) pollution, and achieving the organic combination of environmental protection and economic development. This paper utilizes survey data from 1,345 farm households in the main rice production areas of Jiangxi Province, China, using the example of reduced fertilizer application (RFA) among rice farmers. By constructing a DEA—SBM model with undesirable outputs to measure environmental effects, and applying an endogenous switching model to test the economic and environmental effects of farmers' adoption of green production technologies. The study found that: (1)The behavior of RFA by farmers has a significant positive impact on their net profit per mu(NPPA), helping farmers increase their income, with the increase ranging from 2.05% to 6.54%. (2)The behavior of RFA by farmers has a significant positive impact on agricultural green productivity(AGP), contributing to the improvement of the environment, with the improvement ranging from 44.09% to 45.35%. (3)Heterogeneity analysis found inconsistencies in the income-enhancing and environmental-enhancing effects at different quantiles of NPPA and AGP. Therefore, attention should be placed on improving the agricultural product quality supervision system under the market circulation mechanism, creating land scale conditions conducive to the promotion and application of fertilizer reduction technologies, and promoting the implementation of externality internalization compensation systems.

Whilst Model Reference Adaptive Control theory provides mathematical techniques for achieving the performance of the system without undue dependence upon dynamic systems models, its applicability may not be suitable for systems that are crucial to safety due to suboptimal transient and error convergence performance. In this article, our approach enhances the performance of MRAC by utilizing a Generalized Dynamic Inversion (GDI). Two control actions are permitted under the GDI control law. One control is the particular part that is responsible for enforcing the reference system-constrained behaviors. Another control action is carried out by the control law’s auxiliary component and is incorporated into the standard MRAC control law. This augmented part is referred to as a null control vector, and it is used to enhance the performance of MRAC. The classic MRAC control law, when supplemented with a null vector term consisting of an adaptive gain that changes in response to tracking errors, forces the dynamical system to behave similarly to the reference model. This null vector, in particular, restricts the oscillation intensity of the tracking errors, which is employed to generate the adaptive parameters. It is demonstrated that this critical element of our approach enhances transient performance and ensures that error dynamics vanish asymptotically. Extensive simulations have been conducted to prove the efficacy of the proposed method.

In order to explore more spectrum resources to support sensors and its related applications, cognitive wireless sensor networks (CWSNs) have emerged to identify available channels being underutilized by the primary user (PU). To improve the detection accuracy of the PU signal, cooperative spectrum sensing (CSS) among sensors paradigm is proposed to make a global decision about the PU status for CWSNs. However, CSS is susceptible to Byzantine attack from malicious sensor nodes due to its open nature, resulting in wastage of spectrum resources or causing harmful interference to PUs. To suppress the negative impact of Byzantine attack, this paper proposes a beta distribution function (BDF) for CSS among multiple sensors, which includes a sequential process, beta reputation model, and weight evaluation. Based on sequential probability ratio test (SPRT), we integrate the proposed beta reputation model into SPRT, while improving and reducing the positive and negative impacts of reliable and unreliable sensor nodes on the global decision, respectively. Finally, the numerical simulation results demonstrate that compared to SPRT and weighted sequential probability ratio test (WSPRT), the proposed BDF has outstanding effects in terms of the error probability, and average number of samples under various attack ratios and probabilities.

This study presents a strategic approach to developing applications focused on implementing Large Language Models using the Langchain framework in Python. Three language models are highlighted: GPT-3.5 (turbo mode), LLaMA 2, and Vicuna 7B, each with their distinctive features and capabilities. The methodology used is described in detail, including data extraction from medical reports using zero-shot prompting data extraction techniques, interaction with language models, and structured storage of results. The performance of the models in data extraction is evaluated, presenting metrics such as precision, recall, and F1 score. The results demonstrate high model capability in extracting information, although areas for improvement are identified, particularly in data extraction precision. In conclusion, the efficacy of the models in extracting information from medical histories is not considerably acknowledged, with an emphasis on the importance of improving precision and increasing the volume of trained data for future research in healthcare digitalization.

The Range–Doppler (R-D) model is extensively employed for the geometric processing of Synthetic Aperture Radar (SAR) images. Refining the sensor motion state and imaging parameters is the most common method for achieving high-precision geometric processing using the R-D model, comprising a process that involves numerous parameters and complex computations. In this study, we introduce a novel approach to improve the positioning accuracy of the R-D model, implementing a low-order polynomial to compensate for the original imaging errors without altering the initial positioning parameters. We also design low-order polynomial compensation models with different parameters. The models are evaluated on various SAR images from different platforms and bands, including spaceborne TerraSAR-X and GF3-C images, manned airborne SAR-X images, and unmanned aerial vehicle-mounted miniSAR-Ku images. Furthermore, image positioning experiments involving the use of different polynomial compensation models and various numbers and distributions of Ground Control Points (GCPs) are conducted. The experimental results demonstrate that geometric processing accuracy comparable to that of the classical rigorous positioning method can be achieved even when applying only an affine transformation model to the images. Compared to classical refinement models, however, the proposed image-compensated R-D model is much simpler and easy to implement. Thus, this study provides a convenient, robust, and widely applicable method for the geometric positioning processing of SAR images, offering a potential approach for the joint-positioning processing of multi-source SAR images.

This study discusses the application of deep learning technology in network intrusion detection systems (IDS) and focuses on a new model named CNN-Focal. First, through the review of traditional IDS technology, it analyzes its limitations in dealing with complex network traffic. Then, the design principle of the CNN-Focal model is described in detail, which uses threshold convolution and SoftMax multi-class classification technology to effectively improve abnormal traffic detection's accuracy and efficiency. The experimental results show that CNN-Focal performs well on the open data set, demonstrating the potential and advantages of its application in the natural network environment and providing a new perspective and method for further research of deep learning in the field of network security in the future.

Geothermal energy, being a clean energy source, has immense potential, and accurate wellbore modeling is crucial for optimizing the drilling process and ensuring safety. This paper presents a novel geothermal wellbore model based on the drift-flux approach, tested under three different temperature and pressure well conditions. The proposed model integrates the conservation equations of mass, momentum, and energy, incorporating the gas-liquid two-phase flow drift-flux model and heat transfer model. Key features include handling heat transfer between the for-mation and the wellbore, addressing the slip relationship between gas and liquid phases, and accounting for wellbore friction. The nonlinear equations are discretized using the finite differ-ence method, and the highly nonlinear system is solved using the Newton-Raphson method. Numerical simulation, validation, and comparison with existing models demonstrate the en-hanced accuracy of this model. In our tests, the model achieved high accuracy in calculating bottom hole pressure and temperature, with Mean Relative Errors (MRE) significantly lower than those of other models. These results offer valuable insights for optimizing drilling parameters and ensuring drilling safety. Comparisons indicate that this approach significantly outperforms others in capturing the complex dynamics of geothermal wellbores, making it a superior tool for geo-thermal energy development.

The acquisition of vegetation coverage information is crucial for crop field management, and utilizing visible light spectrum vegetation indices to extract vegetation coverage information is a commonly used method. However, most visible light spectrum vegetation indices do not fully consider the relationships between the red, green, and blue bands during their construction, making it difficult to ensure accurate extraction of coverage information throughout the crop's entire growth cycle. To rapidly and accurately obtain potato vegetation coverage information, drones were used in this study to obtain high-resolution digital orthoimages of potato growth stages. Based on the differences in the grayscale values of potato plants, soil, shadows, and drip irrigation belts, this study presents a combination index of blue and green bands (BGCI) and a combination index of red and green bands (RGCI). The vegetation index intersection method was used with 10 vegetation information indices to extract vegetation coverage, and the differences in extraction accuracy were compared with those of the maximum entropy method and bimodal histogram method. Based on the high-precision fraction vegetation coverage (FVC) extraction results, the Pearson correlation coefficient method and random forest feature selection were used to screen 10 vegetation and 24 texture features, and the top 6 vegetation indices most strongly correlated with the FVC were selected for potato growth stage FVC estimation and accuracy verification. A high-precision potato vegetation coverage estimation model was successfully established. This study revealed that during the potato tuber formation and expansion stages, the BGCI combined with the vegetation index intersection method achieved the highest vegetation coverage extraction accuracy, with overall accuracies of 99.61% and 98.84%, respectively. The RGCI combined with the vegetation index intersection method achieved the highest accuracy, 98.63%, during the maturation stage. For the potato vegetation coverage estimation models, the model based on the BGCI achieved the highest estimation accuracy (R2=0.9116, RMSE=5.7903), and the RGCI also achieved good accuracy in terms of vegetation coverage estimation (R2=0.8987, RMSE=5.8633). In the generality verification of the models, the R2 values of the FVC estimation models based on the BGCI and RGCI were both greater than 0.94. A potato vegetation coverage estimation model was constructed based on two new vegetation information indices, demonstrating good accuracy and universality.

The critical systems, which the failure and malfunction may result in human, environment and financial severe damages, are essential components in various sectors and particularly in energy domains. Although unwished, integration error problems in supervision of critical systems occurs, incurring significant expenses because of operator’s subjective analysis and on hardware topology failures. In this work, a malleable model design approach is proposed to formulate and solve the integration error problem in the critical systems supervision in terms of reliability. A real Hybrid Power Plant (HPP) case is considered as a requirement for a study case with simulated data. A method framework with informal approach (C4 diagram) and formal approach (Hierarchical Coloured Petri Nets) in radial spectrum is applied to the HPP supervision design. Using formal methods, a formulation and solution to this problem through structured, scalable and compact mathematical representations are possible. This malleable model intends to guarantee functional correctness and then reliability of the plant supervision system based on system software architecture. Outcomes suggest corroboration that the malleable model is appropriate for energy domain, and can be used for other types of critical systems, bringing all the benefits of this methodology to the context in which it will be applied.

Objective: This study aims to investigate the relationship between sports psychological capital, coach leadership behavior, and satisfaction among middle school students in the 2023 sports college entrance examination in Chongqing. Methods: Using the structural questionnaire design, this paper carries out a questionnaire survey on the candidates who come to participate in the volleyball specialty college entrance examination in Chongqing, the corresponding database was established and the data were statistically processed by spss21.0 and amos18.0. Results: 1) there was a significant positive correlation between sports psychological capital, coach leadership behavior and examinees satisfaction; 2) sports psychological capital and coach leadership behavior had a certain influence on five dimensions of examinees' personal treatment, personal performance, team integration, team interaction and support from relatives and friends; 3) The sense of self-efficacy in sports psychological capital and coach's leading behavior are the most important to examinees' satisfaction; 4) Both coaches' leadership behavior and sports psychological capital can directly affect examinees' satisfaction, but sports psychological capital is the most important. It can not only directly affect examinees' satisfaction, but also act as an intermediary between coaches' leadership behavior and examinees' satisfaction. Conclusion: Sports College Entrance Examination Students can improve training satisfaction and sports performance by strengthening sports psychological capital training and perceiving coach's leadership behavior; In the leadership behavior of coaches, we should emphasize training and appropriately weaken authoritative teaching, while the training of sense of hope and toughness should be highlighted in sports psychological capital.

The steady rheological behavior of suspensions of solid particles thickened by cellulose nanocrystals is investigated. Two different types and sizes of particles are used in the preparation of suspensions, namely TG hollow spheres of Sauter mean diameter of 69 µm and Solospheres S-32 of Sauter mean diameter of 14 µm. The nanocrystal concentration varies from 0 to 3.5 wt% and the particle concentration varies from 0 to 57.2 vol%. The influence of salt (NaCl) concentration and pH on the rheology of suspensions is also investigated. The suspensions generally exhibit shear-thinning behavior. The degree of shear-thinning is stronger in suspensions of smaller size particles. The experimental viscosity data are adequately described by a power-law model. The variations of power-law parameters (consistency index and flow behavior index) under different conditions are determined and discussed in detail.

As the largest contributor of carbon emissions in China, the building sector currently relies mostly on enterprises’ own effort to report carbon emissions, which usually results in challenges related to information transparency and workload for regulatory bodies, who play an otherwise vital role in controlling the building sector’s carbon footprint. In this study, we established a novel regulatory model known as QCEPM (Quantitative Carbon Emission Prediction Model) by conducting multiple linear regression analysis using the quantities of concrete, rebar, and masonry structures as independent variables, and the embodied carbon emissions of a building as the dependent variable. We processed the data in the detailed quantity list of 20 multi-story frame-structure buildings and fed them to QCEPM for solution. Comparison of the QCEPM-calculated results against the time-consuming and error-prone manual calculation results suggested a mean absolute percentage error (MAPE) of 2.26%. Using this simplified model, regulatory bodies can efficiently supervise the embodied carbon emissions in multi-storey frame structures by setting up carbon quota for a project in its approval stage, allowing the construction enterprise to carry out dynamic control over the audited three most important building materials throughout a project’s planning and implementation phase.

Convolutional Neural Networks (CNNs) are often criticized for their lack of transparency, acting as 'black boxes' in decision-making, a challenge compounded by class imbalance in ECG datasets, which limits their clinical application. This study introduces a CNN-based ECG signal classification model that enhances interpretability and addresses class imbalance through the Synthetic Minority Over-sampling Technique (SMOTE). The model also integrates Uniform Manifold Approximation and Projection (UMAP) for dimensionality reduction and SHAP value analysis, facilitating the visualization of decision boundaries and the assessment of feature contributions. Our evaluation using the MIT-BIH Arrhythmia Database highlights the model's high performance, with accuracy and precision nearing 1.00 for Normal ECG (NOR), Left Bundle Branch Block (LBBB), Right Bundle Branch Block (RBBB), and Ventricular Premature Beat (PVC) in the six-class task. In the ten-class task, the model demonstrated robustness, particularly with an accuracy of 0.9846, precision of 0.9783, recall of 0.9736, and F1 score of 0.9760 in Pacemaker Fusion Beat (PFHB), supported by an AUC of 0.9999 and AP of 0.9885. These results underscore the model's efficacy in cardiac rhythm recognition and resilience to class imbalance. Future research will explore sophisticated model architectures and feature extraction methods to enhance the model's generalization and clinical applicability for early heart disease diagnosis and personalized treatment.

Fintech facilitates financial inclusion by introducing new sustainable and accessible business models in developing countries. Open banking API technology is used by various fintech businesses in both developing and developed countries, with varying effects on financial markets. It changes the financial market distribution structure by separating financial product manufacturing and distribution and intensifying competition between traditional financial institutions and fintech companies. Fintech companies innovate by using this tool to create new business models. In December 2019, Korea established a standardized "open banking API platform," sharing an interbank payment network with fintech companies. It has since shown explosive growth, surpassing the trading volume of the UK, the country that introduced open banking APIs for the first time. This study analyzes new business models fintech companies created using this API technology. Based on existing literature, statistics from the platform operator (the Korea Financial Telecommunications and Clearings Institute), and investigations of 30 Korean fintech mobile applications, this study analyzes new fintech business models that provide financial services using this platform. These companies create sustainable business models by combining multiple APIs. Four representative business models (simple funds transfer, simple payment, cross-border remittance, and asset management) are analyzed to reveal how fintech companies create business models with open APIs.

Given the increased provision of international exchange programmes in higher education, this paper examines students’ perceptions of their learning process in one Erasmus+ programme in Food Innovation and Product Design. Using evaluation model of international exchange programme and triple helix model as the analytical framework, students’ testimonials from 2015–2021 were analysed using a critical discourse analysis. EU and non-EU students had similar perceptions of learning outcomes related to knowledge of the food innovation industry, but non-EU students had a stronger sense of awareness of both the international context and multicultural interaction.

Our main goal is here to make a comparative analysis between the well-known MOND theory and a more recent model called κ-model. An additional connection, between the κ-model and two other novel MOND-type theories: Newtonian Fractional-Dimension Gravity (NFDG) and Refracted Gravity (RG), is likewise presented. All these models are built to overtake the DM paradigm, or at least to strongly reduce the dark matter content. Whereas they rely on different formalisms, however, all four seem to suggest that the universal parameter, a0, appearing in MOND theory could intrinsically be correlated to either the sole baryonic mean mass density (RG and κ-model) and/or to the dimension of the object under consideration (NFDG and κ-model). We could then confer to the parameter a0 a more flexible status of multiscale parameter, as required to explain the dynamics together in galaxies and in galaxy clusters. Eventually, the conformal gravity theory (CFT) also seems to have some remote link with the κ-model, even though the first one is an extension of general relativity, and the second one is Newtonian in essence. The κ-model has been tested on a small sample of spiral galaxies and in galaxy clusters. Now we test this model on a large sample of galaxies issued from the SPARC database.

A new type of artificial block is proposed by modifying the traditional block. Based on the physical model experiment, the wave reflection and run-up characteristics of the new ecological blocks under regular waves were examined, and the influence of the height of the "planting trough" border on the hydrodynamic properties was analyzed. The results indicate that the wave reflection and run-up would decrease with a decrease in the breakwater slope. As wave height increases, wave run-up increases, and the reflection coefficient falls. Wave reflection and run-up increase with an increasing wave period. The relative depth of the water has a smaller impact on the wave reflection than the wave run-up. The reflection coefficient of the new ecological blocks is consistently lower than that of the conventional and continues to decrease as the border of the "planting trough" is raised. The raised borders prevent water loss in the trough, resulting in no significant improvement in the wave run-up performance of the new blocks. The reflection coefficient and the relative run-up R/H gradually increase with the average wave breaking parameter ξ increase. The crude permeability coefficients for the new blocks, New Heights 1 and New Heights 2, are 0.53, 0.53, and 0.54, respectively.

Chlamydia trachomatis (Ct) infections are the most common sexually-transmitted infection (STI). Despite effective antibiotics for Ct, undetected infections or delayed treatment can lead to infertility, ectopic pregnancies, and chronic pelvic pain. Besides humans, chlamydia poses similar health challenges in animals such as C. suis (Cs) in pigs. Based on the similarities between humans and pigs as well as their chlamydia species, we use pigs as a large biomedical animal model for chlamydia research. In this study, we use the pig model to develop a vaccine candidate against Ct. The vaccine candidate consists of TriAdj-adjuvanted chlamydial protease-like activity factor (CPAF) protein. We tested two weekly administration options – twice intranasal (IN) followed by twice intramuscular (IM), or twice IM followed by twice IN. We assessed the humoral immune response not only in serum by CPAF-specific IgG including antibody avidity determination but also in cervical and rectal swabs by CPAF-specific IgG and IgA ELISAs. The systemic T-cell response was analyzed upon in vitro CPAF-restimulation via IFN-γ and IL-17 ELISpots as well as intracellular cytokine staining flow cytometry. Our data demonstrate that while the IN/IM vaccination mainly led to non-significant systemic immune responses, the vaccine candidate is highly immunogenic if administered IM/IN. This vaccination strategy induced high serum anti-CPAF IgG levels with strong avidity as well as high IgA and IgG levels in vaginal and rectal swabs and in uterine horn flushes. In addition, this vaccination strategy prompted a pronounced cellular immune response: Besides inducing IL-17 production, the vaccine candidate induced a strong IFN-γ response by CD4 T cells. In the IM/IN vaccinated pigs, these cells also significantly downregulated their CCR7 expression – a sign for differentiation into peripheral tissue homing effector/ memory cells. Conclusively, this study demonstrates strong immunogenicity of the IM/IN administered TriAdj-adjuvanted Ct CPAF vaccine candidate. Future studies will test vaccine efficacy of this promising Ct vaccine candidate. In addition, this project demonstrates suitability of the Cs pre-exposed outbred pig model for Ct vaccine development. Thereby, we aim to open the bottleneck of large animal models to facilitate the progression of Ct vaccine candidates into clinical trials.

The quality prediction of quaternary structure models of a protein complex, in the absence of its true structure, is known as the Estimation of Model Accuracy (EMA). EMA is useful for ranking predicted protein complex structures and using them appropriately in biomedical research, such as protein-protein interaction studies, protein design, and drug discovery. With the advent of more accurate protein complex (multimer) prediction tools, such as AlphaFold2-Multimer and ESMFold, the estimation of the accuracy of protein complex structures has attracted increasing attention. Many deep learning methods have been developed to tackle this problem; however, there is a noticeable absence of a comprehensive overview of these methods to facilitate future development. Addressing this gap, we present a review of deep learning EMA methods for protein complex structures developed in the past several years, analyzing their methodologies and impacts. We also provide a prospective summary of some potential new developments for further improving the accuracy of the EMA methods.

This article presents a critical review of the current and future state of “business architecture” within the enterprise architecture frameworks. The review is conducted in the following four stages. In the first stage of analysis, the research and publication questions are established. In the second stage, the search for information is designed and implemented using the Prisma methodology, and once the selection criteria were applied, 75 article-type documents were selected from Scopus, WoS, and Dimensions databases. In the third stage, the information analysis is conducted, and then it is synthesized. Finally, in fourth stage, the discussion is elaborated. This research contributes in understanding the current and future trends of business architecture in Industry 4.0. Considering the challenges of the changing market, the results show the need to implement architectures and dynamic business models, including their artifacts, in a globalized context immersed in new technologies.

This paper proposes an electric vehicle routing problem with considering states of charging stations and suggests solution strategies. Charging of electric vehicles is a main issue in the field of electric vehicle routing problem. There are many studies to find locations of charging stations, recharging functions for batteries of vehicles, and so on. However, states of charging stations significantly affect the routes of electric vehicles, which is not much explored. The states may include open or close of charging stations, occupied or empty of charging slots, and so on. This paper investigates how the states of charging stations are estimated and routing strategies are determined. We formulate a mixed integer programming model and suggest how to solve the problem with exact method. Numerical examples provide the optimal routing strategies of electric vehicles in the changing environments of the states of charging stations.

Semi-continuous data are very common in the social science and economics. In this paper, a Bayesian variable selection procedure is developed to assess the influence of exogenous factors including observed and unobserved on the semi-continuous data. Our formulation is based on the two-part latent variable model with polytomous response. We consider two schemes for the penalties of regression coefficients and factor loadings: the Bayesian spike and slab bimodal prior and the Bayesian lasso prior. Within the Bayesian framework, we implement Markov Chains Monte Carlo sampling method to conduct posterior inference. To facilitate posterior sampling, we recast the logistic model in part one as the norm-like mixture model. Gibbs sampler is designed to draw observations from the posterior. Our empirical results show that with suitable hyper-parameters, the spike and slab bimodal method slightly outperforms the Bayesian lasso in the current analysis. Finally, a real example related to the China household finance survey is analyzed to illustrate the application of the methodology.. .

In the face of 21st-century environmental challenges, including climate change, migration pressures, and waste disposal issues, certain healthcare sectors, notably dentistry, pose a significant global environmental footprint with concerns about carbon emissions and waste production. This scoping review delves into the paradox that healthcare, while dedicated to safeguarding health, inadvertently contributes to environmental degradation through waste accumulation and disposal. The analysis of relevant pertinent literature emphasizes the imperative for an environmentally sustainable approach to dental waste measurement, disposal methods, and comprehensive education for stakeholders. Aligned with the World Conference on Sustainable Development and the United Nations' 2030 Agenda, the study adhered to PRISMA-ScR scoping review guidelines and Institute of Medicine's recommendations. The study utilized Medline/PubMed and international organization websites for data retrieval, employing Boolean operator queries in Medline. A systematic literature analysis identified six cross-sectional studies (2004-2018) highlighting variations in dental waste composition due to the lack of standardized identification methods. This heterogeneity underscores the need for a proposed research model, emphasizing comprehensive methodologies and healthcare staff training in waste management. The study advocates for environmentally conscious dental practices, contributing to broader sustainable healthcare goals through sharing of a research protocol for dental solid waste management.

In this paper, we propose an efficient numerical method to solve the diffusive logistic model with a free boundary which is often used to simulate the spreading of the new or invasive species. The boundary movement is tracked by the level-set method, where the Hamilton-Jacobi weighted essentially nonoscillatory (HJ-WENO) scheme is utilized to capture the boundary curve embedded by the Cartesian grids via the embedded boundary method. Then the radial basis function-finite difference (RBF-FD) method is adopted to the spatial discretization and the IMEX scheme is considered for time integration. A variety of numerical examples are carried out to demonstrate the evolution of diffusive logistic model in different initial boundaries.

Background: Atypical teratoid/rhabdoid tumor (AT/RT) is an uncommon and aggressive pediatric central nervous system neoplasm. However, a universal clinical consensus or reliable prognostic evaluation system for this malignancy is lacking. Our study aimed to develop a risk model based on comprehensive clinical data to assist in clinical decision-making. Methods: We conducted a retrospective study by examining data from the Surveillance, Epidemiology, and End Results (SEER) repository, spanning 2000 to 2019. The external validation cohort was sourced from the Children's Hospital Affiliated to Chongqing Medical University, China. To discern independent factors affecting overall survival (OS) and cancer-specific survival (CSS), we applied Least Absolute Shrinkage and Selection Operator (LASSO) and Random Forest (RF) regression analyses. Based on these factors, we structured nomogram survival predictions and initiated a dynamic online risk-evaluation system. To contrast survival outcomes among diverse treatments, we used propensity score matching (PSM) methodology. Molecular data with the most common mutations in AT/RT were extracted from the Catalogue of Somatic Mutations in Cancer (COSMIC) database. Results: The annual incidence of AT/RT showed an increasing trend (APC, 2.86%; 95% CI:0.75-5.01). Our prognostic study included 316 SEER database participants and 27 external validation patients. The entire group had a median OS of 18 months (range 11.5 to 24 months) and median CSS of 21 months (range 11.7 to 29.2). Evaluations involving C-statistics, DCA, and ROC analysis underscored the distinctive capabilities of our prediction model. An analysis via PSM highlighted that individuals undergoing triple therapy (integrating surgery, radiotherapy, and chemotherapy) had discernibly enhanced OS and CSS. The most common mutations of AT/RT identified in the COSMIC database were SMARCB1, BRAF, SMARCA4, NF2, and NRAS. Conclusions: In this study, we devised a predictive model that effectively gauges the prognosis of AT/RT and briefly analyzed its genomic features, which might offer a valuable tool to address existing clinical challenges.

This study conducted experiments to optimize the electro-dewatering of sludge using a dynamic model calculation method and the Wild Horse optimizer. Specifically, we explored two factors that might influence dewatering: the composition of the electrode materials and the strength of the electrical field. Compared to other electrodes commonly used in electro-dewatering—such as RuO2/Ir2O3-Ti, graphite, Ir2O3/Ta2O5-Ti, and Ti—the Electro-kinetic Geosynthetics (EKG) electrode exhibited superior performance. This was determined by considering both energy consumption and model establishment. Our findings also identified electric-field strength as a crucial factor determining the final moisture content. As the electrical intensity increased, the dewatering effect improved, aligning with our model calculations. However, we observed a steep increase in energy consumption per kilogram of filtrate when the electric-field strength exceeded a certain threshold. To optimize the energy consumption of the dehydration process, we constructed a multi-factor model. The simulation results from this model confirmed that electric-field intensity is the primary factor affecting dehydration. It was established that 10 V/cm is a critical threshold for the process.

As urbanization has accelerated, China has started to build smart cities, which have formed smart city clusters. It is critical to coordinate development within smart city clusters to enhance the efficiency of city cluster construction. From the perspective of demographic economics, this study innovatively constructed an evaluation system for the coordinated development of smart city clusters and utilized the coupled coordination degree model to conduct an in-depth study of smart city clusters in Jiangsu Province. The results show that there are clear differences in the development between the three regions of Jiangsu Province: Southern Jiangsu, Central Jiangsu, and Northern Jiangsu. The development within Jiangsu Province is imbalanced, where the overall development trend is high in the southern region and low in the northern region. The main driving factors include geography, the Matthew effect, game thinking, and industrial structure. Accordingly, the results suggest the following recommendations for the coordinated development of smart city clusters: strengthening cross-regional cooperation, promoting data sharing and interoperability, deepening synergistic industrial development, and expanding innovation capacity.

This paper proposes an analytical model of the double-stator spoke-type permanent-magnet vernier machine (DSSTVM) using the subdomain model (SDM), which can be used to calculate the mag-netic field distribution and corresponding electromagnetic parameters of the DSSTVM. The whole field domain is divided into several subdomains according to the magnetic characteristics of each region, within which Laplace's and Poisson's equations are solved accordingly in terms of magnetic vector potential (MVP). Then, the magnetic flux density distribution, back electromotive force (EMF), and electromagnetic torque of the DSSTVM can be obtained correspondingly. Ultimately, finite element analysis (FEA) is adopted to validate the proposed analytical model's effectiveness for quickly predicting the no-load and on-load performances of the DSSTVM.

In several emergency situations, during natural or human-caused disasters, frontline responders need to be able to communicate and collaborate to properly carry out the relief mission. Some countries are building their national Public Safety Mobile Broadband based on cellular LTE technology to provide fast, safe, and secure emergency services. Otherwise, in several emergency situations, the cellular antennas can be overloaded or partially damaged in manner to affect the group communication services. Since few last years, direct device-to-device (D2D) communications have been proposed by 3GPP as an underlay to Long Term Evolution (LTE) networks based on proximity, reuse, and hop gains. This paper focuses on the loosely coupled model based on D2D direct communication for Public Safety context. Many scenarios related to user membership and network management are detailed. Both “less cost” and “optimized tree” approaches are proposed, implemented, and their performance evaluated in terms of network updates number and resulting average Channel Quality Indicator (CQI). Other optimization approaches with different CQI threshold and optimization interval values have been implemented, simulated and their performance are compared with the “optimized tree”.

Australia is a unique continent surrounded by the ocean and the majority of catchments flow to the coast. Some of these catchments are gauged and others are ungauged. There are 405 gauged catchments covering 2,549,000 km2 across the coastal regions of 12 drainage divisions in Australia. Whereas there are 771 catchments conceptualised as ungauged covering additional 835,000 km2. The mean annual rainfall and PET and its spatial and temporal distribution vary significantly from one drainage division to another. We developed a continuous daily streamflow time series of all gauged and ungauged catchments from 1993 onwards. We applied the GR4J lumped conceptual model to these catchments. The performance of gauged catchments was analysed through (i) visual inspection of daily hydrographs, flow duration curves and daily scatter plots, and (ii) performance metrics including NSE and PBias. Based on the NSE and PBias, performance ratings of 80% and 96% of the models respectively were found 'good'. There was no relationship found between the catchment area and model performance. The ungauged catchments were divided into four categories based on distance from potential donor catchments where observed data are available for GR4J model calibration, and Köppen climate zone. The total ungauged catchments represent 24.7% of the total drainage division areas. The streamflow from ungauged catchments was estimated using GR4J model based on the parameters of their donor catchments. Overall, runoff ratios from ungauged catchments were found to be higher compared to their donor gauged catchments, likely driven by their higher rainfall and less PET. This tendency was particularly evident in two drainage divisions – the Carpentaria Coast (CC) and Tanami-Timor Sea Coast (TTS) where ungauged areas comprised 51% and 43% respectively. The mean gauged annual streamflow varied significantly across drainage divisions – 230 GL from South Australian Gulf (SAG) to 146,150 GL in TTS. The streamflow from all ungauged catchments was estimated at 232,200 GL per year. Overall, the average streamflow from all drainage divisions, including gauged and ungauged areas, across the coastal regions of Australia was estimated at 419,950 GL per year. This nationwide estimate of streamflow dataset could potentially enhance our understanding of coastal processes and improvements of marine modelling systems and tools.

Background Acute kidney injury (AKI) is a common comorbidity in the intensive care unit (ICU), with higher mortality rate among those who receive continuous renal replacement therapy (CRRT). This study aimed to investigate the association of white blood cell (WBC) levels with all-cause mortality in AKI patients undergoing CRRT. Method We conducted a post hoc analysis of ICU patient data from multiple centers in Korea. First, the levels of WBCs were classified into four groups based on quartiles. Second, the relationship between different WBC levels and mortality was investigated with the Kaplan-Meier (K-M) survival curves, Cox proportional hazards model, and generalized additivity model (GAM). Finally, we used multiple imputation to avoid bias caused by non-randomized missing data. The endpoints were short-term (28 days) and long-term (90 days) mortality. Result In our analysis, a total of 1,100 ICU patients were included. Among them, 670 (60.90%) and 781 (71.00%) died within 28 and 90 days, respectively. K-M survival curves showed that patients with the lowest WBC levels had the highest risk of mortality for both outcomes. Adjusted multivariate Cox regression analysis confirmed that compared with the reference level (quartile 2), low WBC levels increased the risk of both 28-day mortality (quartile 1, HR = 1.43, 95% CI: 1.13–1.83, P = 0.004) and 90-day mortality (quartile 1: HR = 1.32; 95% CI: 1.05-1.66, P = 0.016). GAM analysis showed a non-linear, U-shaped relationship between pre-CRRT WBC levels and all-cause mortality (non-linear P < 0.05). Conclusion The baseline WBC level is an independent predictor of prognosis for ICU patients receiving CRRT. Patients in the lowest WBC quartile had the highest risk of all-cause mortality. These results provide further evidence that early observation and intervention may have a prognostic value for these high-risk patients.

Fabry-Pérto (FP) cavity is the essential component of ultra-stable laser (USL) for gravitational wave detection, which couples multi-physic (Optical/Thermal/Mechanics) fields and requires ultra-high precision. To satisfy the requirements of precise and efficient design, a multi-physic coupling optimization method for fixing cubic FP cavity based on data learning is proposed. A multi-physic model for the cubic FP cavity is established and the performance is obtained by finite element analysis. The key performance indices (V, wF, wF) and key design variables (d, l, F) are determined considering the features of the FP cavity. The 49 sets of data by orthogonal experiment are acquired for the establishment and comparison of different data learning models (NN, RSF, KRG). The result turns out that the neural network has the best performance. Based on NSGA-II, the Pareto optimal front is obtained and the optimal combination of design variables is finally determined as {5,32,250}. The performance after optimization has proven to be a great improvement, of which the displacement under the fixing force and vibration test are decreased by more than 60%. The optimization strategy can not only help the design of the FP cavity but also enlighten other optimization fields.

The issue of equipment layout in multi-floor satellites consists of two primary parts: allocating the equipment to the satellite's layers and placing the equipment in each layer individually. In reviewing the past literature in this field, firstly, the issue of assigning equipment to layers is observed in a few articles and next in the layout part, the non-overlapping constraint has always been a challenge, particularly for components that do not have a circular cross-section. In addition to presenting a heuristic method for allocating equipment to different layers of the satellite, this article presents a robust flexible programming model (RFPM) for the placement of equipment at different layers, taking into account the inherent flexibility of the equipment in placement and the subject of uncertainty. This model is based on the existing uncertainty between the distances of cuboid equipment which has not been addressed in any of the previous research, and by comparing its outputs with cases from past studies, it demonstrates a significantly higher efficiency in placing the equipment and meeting the limit of non-overlapping constraints between the equipment. Finally, it would be possible to reduce the design time in the conceptual and preparatory stages, as well as the satellite's overall size, while still satisfying other constraints like stability and thermal limitations, moments of inertia and centre of gravity.

In this paper we compare the effects of forecasting demand using individual (disaggregated) components versus first aggregating the components either fully or into several clusters. Demand streams are assumed to follow autoregressive moving average (ARMA) processes. Using individual demand streams will always lead to a superior forecast compared to any aggregates, however we show that if several aggregated clusters are formed in a structured manner then these subaggregated clusters will lead to a forecast with minimal increase in mean-squared forecast error. We show this result based on theoretical MSFE obtained directly from the models generating the clusters as well as estimated MSFE obtained directly from simulated demand observations. We suggest a pivot-algorithm, that we call Pivot Clustering, to create these clusters. We also provide theoretical results to investigate sub-aggregation, including for special cases such as, aggregating MA(1) streams and ARMA streams with similar or same parameters.

This work focuses on addressing the dynamic positioning and trajectory tracking problem for a 4 degree-of-freedom (DOF) unmanned underwater vehicle (UUV) in the presence of nonlinear dynamics, parametric uncertainties, system constraints, and time-varying external disturbances. To tackle this problem, a disturbance observer-based control (DOBC) scheme is proposed. The scheme is structured around the model predictive control (MPC) method integrated with an extended active observer (EAOB). Compared to the conventional disturbance observer, the EAOB has the unique ability to handle both external disturbances and system/measurement noises simultaneously. The EAOB leverages a combination of sensor measurements and a system dynamic model to estimate disturbances in real-time, which allows continuous estimation and compensation of time-varying disturbances back to the controller. The proposed disturbance observer-based MPC (DOBMPC) is implemented by feeding the estimated disturbances back into the MPC’s prediction model, which forms a robust adaptive controller with a parameter-varying model. The proposed control strategy is validated through simulations in a Gazebo and Robot Operating System (ROS) environment. The results show that it can effectively reject unpredictable disturbances and improve the UUV’s control performance.

Gold nanoparticles (AuNPs) have been used in a broad range of applications conferring to bio-molecules diverse proprieties such as deliver, stabilization and reduction of adverse effects of drugs or plant ex-tracts. Polyphenolic compounds from Bacopa procumbens (BP) are able to modulate proliferation, adhesion, migration and cell differentiation, reducing artificial scratch area in fibroblast cultures and promoting wound healing in in vivo model. Here, chemically synthetized AuNPs conjugated with BP (AuNP-BP) were characterized by Uv-Vis, ATR-FTIR, DLS and zeta-potential. Results showed over-lapping FTIR spectra of polyphenolic compounds from B. procumbens capping the AuNPs, stable size by the DLS and zeta potential, AuNP-BP was 44.58 nm, the zeta-potential of AuNPs was -36.3±12.3 mV after conjugation with the BP; - (AuNP-BP), the zeta-potential was reduced to -18-2±7.02 mV. Enhancement of wound healing effect were evaluated by morphometric, histochemical and FTIR changes in rat wound excision model. Results showed that the nanoconjugation process reduced 100 folds BP concentrations to have the same wound healing effect of BP alone. Besides histological and FTIR spec-troscopy analyses, demonstrated that AuNP-BP treatment displayed better macroscopical performance; the reduction on inflammatory cells, and the increased synthesis and better organization of collagen fibers.

Rapid urbanization has led to many ecological problems such as landscape fragmentation, decreased landscape connectivity, and decreased biodiversity. Building an ecological security pattern is an important way to ensure ecological security and maintain sustainable urban development. Harbin is an important large-scale city in northeastern China, and the urban central district of Harbin is used as the study area. Ecological sensitivity assessment, MSPA, gravity model, landscape connectivity assessment and MCR model were used to extract ecological source areas, ecological corridors and ecological nodes in the study area to construct and optimize the ecological security pattern. Research shows that: A total of 23 ecological source areas were identified, mainly located along the Songhua River in the central part of the study area and in the mountain forest areas within the A-cheng District in the southeastern part of the study area. 48 ecological corridors were extracted, mainly in Daowai District, A-cheng District and the eastern part of Xiangfang District. There are 8 important ecological corridors and 10 important connecting corridors. 61 ecological nodes of the first level and 65 ecological nodes of the second level were extracted. High, higher, medium, lower and low security areas were classified based on the minimum cumulative resistance surface, with the highest proportion of high ecological security areas accounting for 45.75% of the study area. 65 ecological breakpoints were extracted and restoration measures were proposed. Finally, The structure of the ecological security pattern optimization of "two axes, two belts and four areas" is proposed, and corresponding ecological management measures are put forward. The experimental system of this study can provide new ideas for the construction of ecological security patterns in other regions and provide scientific support for the ecological sustainable development of similar urban areas.

Deep learning is emerging in many industrial sectors in hand with big data analytics to streamline production. In the biomanufacturing sector, big data infrastructure is lagging comparatively to other industries. A promising approach is to combine Deep Neural Networks (DNN) with prior knowledge in Hybrid Neural Network (HNN) workflows that are less dependent on the quality and quantity of data. This paper reviews published articles over the past 30 years on the topic of HNN applications to bioprocesses. It revealed that HNNs were applied to various bioprocesses, including microbial cultures, animal cells cultures, mixed microbial cultures, and enzyme biocatalysis. HNNs were mainly applied for process analysis, process monitoring, development of software sensors, open- and closed-loop control, batch-to-batch control, model predictive control, intensified design of experiments, quality-by-design, and recently for the development of digital twins. Most previous HNN studies combined shallow Feedforward Neural Networks (FFNNs) with physical laws, such as macroscopic material balance equations, following the semiparametric design principle. Only recently, deep HNNs based on deep FFNNs, Convolution Neural Networks (CNN), Long Short-Term Memory (LSTM) networks and Physics Informed Neural Networks (PINNs) have been reported. The biopharma sector is currently a major driver but applications to biologics quality attributes, new modalities, and downstream processing are significant research gaps.

This research paper is about to obtain new soliton solutions to the M-fractional (1+1)-dimensional nonlinear Westervelt model by utilizing $\exp_a$ function and modified simplest equation techniques. The gained solutions involving dark, bright, periodic, dark-bright and other solitons. These results have many applications in wave propagation of sound waves, high amplitude in medical imaging and therapy. Achieved results are verified by Mathematica tool and the effect of M-fractional derivative on the solutions is explained through 2-Dimensional, 3-Dimensional and contour plots. At the end, these techniques are simple, fruitful and effective to deal with nonlinear FPDEs.

Entangled metallic wire material (EMWM) can be utilized as a novel elastic element in vibration isolation devices for mechanical actuators. This paper presents a vibration experiment aimed at investigating the degradation behavior of mechanical performance in EMWM under cyclic compressive environment. An electric vibration testing system, coupled with an isolation structure, is employed to apply compressive loads to the EMWM specimens. Through visual observations and quasi-static compression tests, the variations in geometric morphology and mechanical properties are studied, considering different relative densities and stress amplitudes. The results incidate a significant reduction in the compressed dimension of the specimens as the number of cycles increases, without any wire fractures or wear. Moreover, the mechanical properties exhibit an increasing secant modulus and a decreasing loss factor. These variations ultimately lead to a gradual deviation of the vibration characteristics of the isolation structure from its design state. To predict the mechanical property degradation of EMWM, prediction models are proposed, incorporating dimension, modulus and damping by fitting the obtained results. This research provides valuable experimental data and presents an effective method to determine the operational lifetime of vibration isolators utilizing EMWM.

When analyzing user geospatial information through deep learning methods, it is typically necessary to annotate existing geospatial data. Currently, manual annotation methods are commonly employed, suffering from issues related to low efficiency and accuracy. This design is based on the TensorFlow deep learning framework and first realizes the BiLSTM+CRF+AGG deep learning model. Among the models, AGG is the aggregation layer, which is introduced to solve the problem of solid particle size equilibrium. Secondly, based on the characteristics of original data and professional data, an automatic labeling algorithm is proposed. The algorithm first preprocesses the acquired original data set and professional data set, The most valuable unlabeled data set which can make the training model converge quickly is selected from the original data set as the target data set. Sort the target data set based on preset rules and set annotation parameters for the sorted target data set. Based on the set annotation parameters, the corpus is synthesized and used as the annotation result. Thirdly, based on the active learning strategy, a manual annotation auxiliary scheme is proposed, and an Excel generation module that is convenient for manual annotation correction is designed and developed to further improve the efficiency and quality of annotation through iterative processing. The combination of the BiLSTM+CRF+AGG deep learning model and high-quality annotation can accurately identify non-standard, incomplete, or even incorrect geographical information entities. This annotation method has found successful practical application within the context of the research project and has been granted an invention patent.

In recent years, the high-frequency abnormal price fluctuations of small-scale agricultural products have been detrimental to market stability. The traditional method based on statistical data of production factors can no longer accurately predict abnormal price fluctuations. Taking scallions as a case, the paper identifies price influencing factors from massive network information, and analyzes the causes and changing characteristics of price fluctuations from four perspectives: market supply, economic environment and market sentiment, and attention. Initially, the study employs an LDA topic model to extract factors from online sentiment data over the past four years, including market supply and demand, economic conditions, related agricultural prices, and market attention. Subsequently, using the SO-PMI algorithm to expand domain-specific lexicons and employing semantic and sentiment analysis with syntactic parsing, the study aims to improve the accuracy of sentiment quantification in text analysis. Furthermore, cointegration and Granger causality tests validate the significant impact of these factors on scallion price fluctuations, mitigating spurious regression issues. Finally, by employing a TVP-VAR model, the study compares the impulse responses and shock magnitudes of various factors in different time and spatial dimensions. It also delves into the mechanisms of heterogeneous impacts and trends in scallion prices, considering the corresponding socio-economic context and public sentiment events within specific time windows, thereby providing valuable decision-making insights for the healthy development of agricultural markets.

This article focuses on methods for designing heuristic models within the paradigm of systems theory and in the disciplinary context of intercultural communication. The main question arises from the striking observation that the common language is insufficient to develop knowledge about human communication, especially when many factors of complexity (such as ambiguity, paradoxes, or uncertainty) are involved in the composition of an abstract research object. This epistemological, theoretical, and methodological problematic is one of the main challenges to the scientificity of anthropological theories and concepts on culture. Moreover, these questions lie at the heart of research in intercultural communication. Authors and theorists in the complexity sciences have already stressed the need, in such case, to think in terms of models or semiotic representations, since these tools of thought can mediate much more effectively than unformalized language between the heterogeneous set of perceptions arising from the field of experience, on the one hand, and the philosophical principles that organize speculative thought, on the other. This sets the scene for a reflection on the need to master the theory of heuristic models when it comes to developing scientific knowledge in the field of intercultural communication. In this essay, my first aim is to make explicit the conditions likely to ensure the heuristic value of a model, while my second aim is to clarify the operational function and required level of abstraction of certain terms such as concepts, categories, headings, models, systems, or theories that are among the most commonly used by academics in their descriptive accounts or explanatory hypotheses. To achieve this second objective, I propose to create cognitive meta-categories to identify the three (nominal, cardinal or ordinal) roles of words in the reference grids we use to classify our ideas, and to specify how to use these meta-categories in the construction of our heuristic models. Alongside the theoretical presentation, examples of application are provided, almost all of which are drawn from my own research into the increased cultural vigilance of the majority population in Quebec since the reasonable accommodation crisis in this French-speaking province of Canada. The typology I propose will perhaps help to avoid the confusions regularly committed by authors who attribute only cosmetic functions to words that nevertheless have a highly heuristic value, and who forget to consider the logical leaps of their theoretical thinking in the construction of heuristic models.

"Finding fresh water in the ocean of data." is a challenge that all deep learning domains struggle with, especially in the area of hyperspectral image analysis. As hyperspectral remote sensing technology advances by leaps and bounds, there are increasing amounts of hyperspectral images(HSIs) can be available. Whereas in fact, these unlabeled HSIs are powerless to be used as material to driven a supervised learning task due to the extremely expensive labeling costs and some unknown regions. Although learning-based methods have achieved remarkable performance due to their superior ability to represent features, at the cost, these methods are complex, inflexible and tough to carry out transfer learning. In this paper, we propose the "Instructional Mask AutoEncoder"(IMAE), which is a simple and powerful self-supervised learner for HSI classification that uses a transformer-based mask autoencoder to extract the general features of HSIs through a self-reconstructing agent task. Moreover, we utilize the metric learning to perform an instructor which can direct the model focus on the human interested region of the input so that we can alleviate the defects of transformer-based model such as local attention distraction, lack of inductive bias and tremendous training data requirement. In downstream forward propagation, instead of global average pooling, we employ a learnable aggregation to put the tokens into fullplay. The obtained results illustrate that our method effectively accelerates the convergence rate and promotes the performance in downstream task.

Technology has transformed aeroponics, providing numerous advantages over traditional soil-based agriculture. However, there remains a need for comprehensive information on the types of technology employed in aeroponics and their impact on the growing process. This paper presents a literature review of 47 studies published between 2012 and 2023 in peer-reviewed journals and conference proceedings. As a result, it identifies the status and tendencies in the usage of technology in aeroponics as well as the main opportunities and challenges. Furthermore, this paper introduces the Technology Adoption and Integration in Sustainable Agriculture (TAISA) model. TAISA is a model that identifies the degree of technology integration in any sustainable agriculture system to determine how technology affects production and quality. Overall, the systematic review suggests that technology can play a vital role in improving the efficiency and sustainability of aeroponic farming. However, careful consideration must be given to the costs and technical requirements associated with using these technologies. Moreover, the TAISA model reveals that technology has primarily been employed in creating new processes that are not possible to implement without the help of technology. Therefore, we conclude that technology use has taken root in aeroponics and can be promoted to improve sustainable agriculture.

Ensuring fire safety is an important condition for the successful operation of industrial enterprises. It is necessary to detect the threat of fire before ignition. An indicator of danger is the appearance of gas, which occurs as a result of unauthorized heating of equipment. Gas sensors make it possible to detect the appearance of gases characteristic of the decomposition of materials at the stage of smouldering and pyrolysis, which cause a change in the composition of the atmosphere. This paper presents a mathematical method for the rational placement of gas analyzers for premises of potentially hazardous industries. It is the rational placement of gas sensors, which ensures safety, taking into account economic feasibility that determines the effectiveness of their use. For the first time, the analysis of gas accumulation during the movement of the flow from the source to the ceil-ing, then propagation to the location of the sensors, is used for the first time to select the placement of gas sensors. Depending on the permissible values of the gas volume, the placement and number of gas sensors are selected. The calculation of the conditions for the rational placement of gas sen-sors for the most common indicators, such as carbon monoxide and hydrogen at different sizes and heights of rooms, is carried out. The method of calculating the location of gas analyzers makes it possible to diagnose and predict fire hazard at technological facilities on the basis of gas control, and compare the obtained values with the maximum permissible values. This method provides cal-culation of the coordinates of the gas source from the coordinates of the triggered sensors. Knowing the coordinates of all sensors, the coordinates of the sensors that gave the alarm, and the formula for determining the volume of the gas cloud under these sensors, it is possible to assess the localization of the source of dangerous gas in the protected room. This increases the efficiency of the fire safety system. The method makes it possible to control the layout of sensors depending on the volume of protected premises, types of production, the creation of new sensors, changes in the composition of hazardous gas in different technological conditions.

In this paper, we consider the one-dimensional Ising model (shortly, 1D-MSIM) having mixed spin-(s,(2t−1)/2) with nearest neighbors and the external magnetic field. We establish the partition function of the model by means of the transfer matrix. Under a null boundary condition, we compute certain thermodynamic quantities for the 1D-MSIM. We find some precise formulas to determine the model’s free energy, entropy, magnetization, and susceptibility. By examining the model’s associated iterative equations, we use the cavity approach to investigate the phase transition problem. We numerically determine the model’s periodicity.

Water is one of the most critical factors affecting environmental health. For this reason, estimating and monitoring the behavior of water in nature and preventing water pollution before it occurs are advantageous to avoid problems that may occur in terms of environmental health. In order to predict the behavior of water, the hydrological cycle needs to be evaluated on a basin basis. At this point, hydrological models can be used to make mathematical representations of hydrologi-cal processes. These models play an essential role in predicting and monitoring problems such as poor water quality, pollution, particle and sediment transport, and proliferation of oil and petro-leum derivatives among frequently encountered issues in environmental health. In this study, a 2D surface water model was created using soil and water assessment tool (SWAT) to simulate the lotic ecosystem and existing water quality in Tatlıçay Basin and to propose solutions for im-proving environmental health in Cankiri provincial center in Türkiye. The accuracy of the input data and the validity of the model were checked with the calibration and validation studies by using the monthly or 3-monthly observation data of the General Directorate of State Hydraulic Works’ flow observation & water quality stations from 2016 to 2020. The aim was to provide the opportunity to produce fast, accurate, and practical solutions in the face of negative scenarios with this model. This modelling study obtained successful results in the calibration and valida-tion process with very few observed data. With this study, a significant contribution to the litera-ture on environmental health is made, as there aren't many examples of hydrological modeling from the Middle East.

Top-down models are defined by hardware architects to provide information on the utilization of the different hardware components. The target is to isolate the users from the complexity of the hardware architecture while giving them insight into how efficiently the code is using the resources. In this paper, we explore the applicability of 4 top-down models defined for different hardware architectures powering state-of-the-art HPC clusters (Intel Skylake, Fujitsu A64FX, IBM Power9, and Huawei Kunpeng 920) and propose a model for AMD Zen 2. We study a parallel CFD code used for scientific production to compare these 5 Top-Down models. We evaluate the level of insight achieved, the clarity of the information, the ease of use, and the conclusions that each one allows us to reach.

The rapidly evolving field of artificial intelligence (AI) continues to witness the introduction of innovative open-source pre-trained models, fostering advancements in various applications. One such model is Llama 2, an open-source pre-trained model released by Meta, which has garnered significant attention among early adopters. In addition to exploring the foundational elements of the Llama v2 model, this paper investigates how these early adopters leverage the capabilities of Llama 2 in their AI projects. Through a qualitative study, we delve into the perspectives, experiences, and strategies employed by early adopters to leverage Llama 2's capabilities. For the purpose of data analysis, the capabilities inherent in the Llama 2 model were employed to conduct keyword extraction from the context of the early adopters' case studies. The findings shed light on the model's strengths, weaknesses, and areas of improvement, offering valuable insights for the AI community and Meta to enhance future model iterations. Additionally, we discuss the implications of Llama 2's adoption on the broader open-source AI landscape, addressing challenges and opportunities for developers and researchers in the pursuit of cutting-edge AI solutions. The present study constitutes an early exploration of the Llama 2 pre-trained model, holding promise as a foundational basis for forthcoming research investigations.

Our lives are comprised of moment-to-moment activity experiences. According to the Model of Human Occupation (MOHO), our occupational experiences can be affected by volition, which consists of personal causation, values, and interests. This study investigated how momentary volition affected occupational satisfaction and mind-wandering while performing occupations. This study also examined the relationship between momentary volition and the overall life perspectives of life satisfaction and life balance. Undergraduate students participated in this cross-sectional study. The experience sampling method (ESM) was used to measure students’ momentary states such as activity, volition, occupational satisfaction, and mind-wandering. After conducting the ESM, the participants’ life satisfaction was measured using the Satisfaction With Life Scale (SWLS), and their life balance was measured by the Life Balance Inventory (LBI). Forty-two participants and 1,092 sampling data were included in the analysis. Momentary personal causation, values, and interests contributed to occupational satisfaction. Mind-wandering was predicted negatively by interests but positively by personal causation. Momentary interests were positively correlated with SWLS and LBI scores. This study demonstrated that momentary volition was associated with occupational satisfaction and engagement, as well as life satisfaction and balance, in undergraduate students.

In metal continuous casting process is important to estimate the temperature evolution of casted section along machine from meniscus (point in which liquid metal is poured) to cutting machine where product is cut at commercial length. Particularly in the case of large sections, a convenient approximated model to achieve this goal with a feasible computational effort, is the so called travelling slice: the transversal section of casted product is subjected to different thermal boundary conditions (e.g. thermal flux, radiation, convection) that are found during the movement at constant speed from meniscus to the end of machine. In the case of an axisymmetric section, a comparison with the exact solution can be easily achieved. The article will show pros and cons of both, namely the far lower computational cost of travelling slice model without losing precision. Results confirm the validity of the travelling slice approach also at low casting speed and huge dimensions.

Coronavirus disease 2019 (COVID-19) is a high contagious respiratory infectious disease that has afiected millions of people worldwide. Initially, basic public health measures were implemented to control specially the spread of such virus. However, vaccination has emerged as a highly efiective strategy in combating COVID-19 and reducing its transmission. Several efiective and safe vaccines have been approved to prevent the inadvertent spread of the disease. In this study, a modeling approach is used to analyze the impact of these vaccines on the dynamics of COVID-19. By applying a higher-order numerical method, the model is solved based on reported cases in Pakistan. A spectral method is employed for the numerical solution, and the model is simulated to assess the efiects of vaccination. The Next-generation method is used to calculate the threshold quantity, known as R0, which indicates the potential for disease transmission. The study also includes a detailed stability analysis, examining the invariance properties of the model solution and discussing equilibrium points and their stability in disease-free and endemic states. Furthermore, the study presents graphical representations of the influence of special parameters on the dynamics of the pandemic.

ORB (Oriented FAST and Rotated Brief) features are the most commonly used features in visual SLAM and visual odometry that have high computational speed, and rotation scale invariance. However, due to the homogenization of ORB features, the corner properties of specific features are poor in some artificial environments, and it can lead to poor matching performance when the environmental texture is not rich. The underlying reason is that the pixel grayscale changes in the less-richly textured regions on the image are not obvious, leading to a certain degree of mis-matching in the matching process. At the same time, when the camera motion speed is low, there is much overlap between adjacent frames. This results in minimal or almost no changes in the projection of feature points, and the system is highly sensitive to errors, In this case, even small errors can cause significant fluctuations in the calculation results. In response to the above issues, an improved feature point method for stereo vision mileage calculation is proposed to solve the problem of system stability deterioration when cameras move at low speeds in artificial envi-ronments. Firstly, weight calculation based on different texture regions is used to solve the problem of low corner properties of feature points caused by environmental texture differences. Then, keyframes are used for motion model estimation to improve the system's stability under low-speed motion. The experimental results of the dataset showed that the key frame rate was optimal between 10% and 12%, and the positioning accuracy was higher than these open-source systems compared with three common open-source VO systems.

This work aims to describe the dielectric behaviours of four main tissues in the human forearm using mathematical modelling, including fat, muscle, blood, and bone. Determining the electrical response of multiple tissues can help develop physiological monitoring of an organ or a body’s section by filtering out the impedance contributions from the surrounding tissues to blood flow-induced impedance variations. Multi-frequency bioimpedance analysis (MF-BIA) was initially performed using the finite element method (FEM) with a 3D forearm model followed by a pilot study to characterise the response of actual forearm tissues from 1 kHz to 349 kHz. Both the simulation and experimental results were fitted to a single-dispersion Cole model (SDCM) and a multi-dispersion Cole model (MDCM) to determine the Cole parameters for each tissue. The correlation analysis and Bland-Altman plot indicated a good fit between raw and fitted impedance values using both SDCM and MDCM. Overall, MDCM exhibited better performance in fitting and estimation of the Cole parameters with correlation coefficient (R2) of 0.99 and 0.97, root mean squared error (RMSE) of 0.09 Ω and 0.14 Ω, and mean difference (mean±standard deviation) of 0.00±0.09 Ω and -0.03±0.14 Ω for the real part and imaginary part of impedance, respectively.

A mathematical model is proposed to analyze the spreading dynamics of COVID-19. By using the parameters of the model, namely the basic reproduction number (R0) and the attenuation constant (k), the daily number of infections (DNI) and the cumulative number of infections (CNI) are deduced and shown to be in good agreement with experimental data. This model effectively addresses three key issues: explaining the waveform pattern of DNI, predicting the occurrence of the second wave of infection, and understanding the competitive spread of two viruses in a region. The findings demonstrate that these significant challenges can be comprehensively tackled using a simple mathematical framework. The theoretical insights derived from this model hold potential in guiding the estimation of the severity of an infection wave and formulating effective strategies for the control and mitigation of epidemic outbreaks.

During the last years, the increasing evidence of dietary antioxidant compounds and reducing chronic diseases and the relationship between diet and health have promoted an important innovation on the baked product sector, aiming at healthier formulations. This study aims to develop a tool based on mathematical models to predict baked goods total antioxidant capacity (TAC). The high variability of antioxidant properties of flours based on the aspects related to type of grains, varieties, proximal composition and processing, among others, makes very difficult to innovate on food product development without specific analysis. Using Total phenol content (TP), Oxygen radical absorbance capacity (ORAC) and Ferric reducing antioxidant power assay (FRAP) as proxies of antioxidant capacity. Three Bayesian-type models are proposed based on a double exponential parameterised curve that reflects the initial decrease and subsequent increase as a consequence of the observed processes of degradation and generation, respectively, of the antioxidant compounds. Once the values of the main parameters of each curve have been determined, support vector machines (SVR) with exponential kernel were used to predict, based on the temperature and duration of baking as well as the values of proteins and fibers of each native grain, the values of TAC during the baking time.

This paper focuses on a joint model to analyse longitudinal proportion and survival data. After transforming the longitudinal proportional data by a logit function, we adopt a partially linear mixed-effect model for it, in which nonlinear function of time is fitted via using B-splines technique and a centered Dirichlet Process Mixture Model (CDPMM) is specified for a general distribution of random effects. The survival data is assumed to a Cox proportional hazard model, the sharing random effects joint model is developed for the two types of data. Combining the Gibbs sampler and the Metropolis-Hastings algorithm, we propose a Bayesian Lasso (BLasso) method to simultaneously estimate unknown parameters and select important covariates. Simulation studies are conducted to investigate the finite sample performance of the proposed methods. An example from the MA.5 research experiment is used to illustrate the proposed methodologies.

Two monoclonal antibodies (mAbs) against human epidermal growth factor receptor 2 (HER2), trastuzumab and pertuzumab, were clinically approved. We previously developed a highly sensitive and specific anti-HER2 mAb, H2Mab-139 (mouse IgG1, kappa). In this study, we produced a defucosylated IgG2a version of anti‑HER2 mAb (H2Mab-139-mG2a-f) to enhance ADCC-mediated antitumor activity. H2Mab-139-mG2a-f exhibits a high binding affinity in flow cytometry with the dissociation constant (KD) determined to be 3.9 × 10‑9 M and 7.7 × 10‑9 M against HER2‑overexpressed Chinese hamster ovary (CHO)-K1 (CHO/HER2) and HER2-positive BT-474 cells, respectively. Moreover, we showed that H2Mab-139-mG2a-f exerted ADCC and complement-dependent cytotoxicity against CHO/HER2 and BT-474 cells in vitro and exhibited potent antitumor activities in the xenograft models. These results indicated that H2Mab-139-mG2a-f exerts antitumor effects against HER2-positive human breast cancers and could be useful for an antibody treatment regimen for HER2-positive human cancers.

Cropland area is closely related to food production. More previous focuses were paid on impacts of extreme events on food production, but less on cropland dynamics. This study took the Farming-Pastoral Ecotone of Northern China (FPEN) as a case area, to investigate its cropland area dynamics and driving factors in view of perspectives of extreme events, environmental conditions, socioeconomic development, urban expansion, and ecological construction. We used ridge regression approach to quantify contributions of these drivers to cropland area dynamics. Results showed that cropland area increased significantly at a rate of 333.5km2/a during 1992−2020 and were spatially clustered in east of the FPEN. Impact extent and size each driving factor on cropland trend presented large spatiotemporal differences, but ecological construction (EC) had overall the greatest impact on cropland area changes, followed by urban expansion (UE). In comparison, TL10p has the smallest. UE-dominated areas increased 41.9% since 2010s, but still less than EC. Furthermore, we found that extreme events effects on cropland area trend evidently increased. Particularly, TH90p displayed the most increase (~99.4%). Cropland area changes dominated by extreme temperature events in 2010−2020 increased nearly six times than that in 1992−2010. These findings suggest that increasing impacts of extreme weather events on cropland area changes should be cautioned.

Volcanic emissions (ash, gas, aerosols) dispersed in the atmosphere during explosive eruptions generate hazards affecting aviation, human health, air quality and the environment. We document for the first time the contamination of airspace by very fine volcanic ash due to sequences of tran-sient ash plumes from Mount Etna. The atmospheric dispersal of sub-10 μm (PM10) ash is mod-elled using the WRF-Chem model coupled online with meteorology and aerosols and offline with Mass Eruption Rates (MER) derived from near-vent Doppler radar measurements and inferred plume altitudes. We analyse two sequences of paroxysms with widely varied volcanological conditions and contrasted meteorological synoptic patterns in October–December 2013 and on 3-5 December 2015. We analyse the PM10 ash dispersal simulation maps in terms of time-averaged columnar ash density, concentration at specified flight levels averaged over the entire sequence interval, and daily average concentration during selected paroxysm days at these flight levels. The very fine ash from such eruption sequences is shown to easily contaminate the airspace around the volcano within a radius of about 1000 km in a matter of a few days. Synoptic patterns with relatively weak tropospheric currents lead to the accumulation of PM10 ash at a re-gional scale all around Etna. In this context, closely interspersed paroxysms tend to accumulate very fine ash more diffusively in the lower troposphere and in stretched ash clouds higher up in the troposphere. Low-pressure, high-winds weather systems tend to stretch ash clouds into ~100 km-wide clouds forming large-scale vortices 800-1600 km in diameter. Daily average PM10 ash concentrations commonly exceed the aviation hazard threshold up to 1000 km downwind from the volcano and up to the upper troposphere for intense paroxysms. Vertical distributions show ash cloud thicknesses in the range 0.7–3 km, and PM10 sometimes stagnating at ground level, represent a potential health hazard.

Nowadays, consumers have growing expectations for healthier and higher-quality food, and sustainable food choices are also taking on an increasingly central role. This paper assesses the environmental loads and energy resources of vegan, semi-vegetarian, and traditional restaurant soups and main dishes, focusing on preparation and cooking phases based on the life cycle assessment. The optimal menu samples were selected based on statistical methods. Mann-Whitney and Krus-kal-Wallis tests were applied to investigate restaurant products' distribution and carbon footprint. Based on the results, the preparation phases have a more significant impact. The environmental loads for the life cycle of vegan and semi-vegetarian menus are lower. Furthermore, a sustainability assessment model was developed by integrating lean and life cycle assessment approaches called "GreenCycLEAN." Research results are helpful for the sustainability of catering establishments.

A locally-rotationally-symmetric Bianchi-I model filled with strange quark matter (SQM) is explored in f(R, T) gravity. We take f(R, T) = R + 2 f(T) = R + 2λT, where R is the Ricci scalar, T is the trace of energy-momentum tensor and λ is an arbitrary constant. Exact solutions are obtained by assuming that the expansion scalar is proportional to the shear scalar. This yields a constant value for the deceleration parameter, q = 2, which corresponds to the decelerated phase of the universe. The model is found to be physically viable for λ < −1. SQM during early evolution mimics ultra-relativistic radiation whereas at late times, it behaves as dust, quintessence or even the cosmological constant depending on the value of λ. The effective matter acts as a stiff fluid irrespective of the matter content and of the f(R, T) terms. The model is shear free at late times but remains anisotropic throughout the evolution. In the absence of the f(R, T) terms, SQM accelerates the universe. In the specific case when SQM vanishes at late times, the effect of f(R, T) is to accelerate the universe. The model admits the possibility that SQM could be an alternative to dark energy.

The application of warm-mixing technology brings considerable economical and environment benefits by decreasing the mixing temperature during warm asphalt mixture(WMA) production. However, the possible water residue also generates concerns in moisture susceptibility. For deep investigation on the influencing factors and mechanism of the moisture susceptibility of WMA, surface free energy(SFE) test and laboratory tests are applied in this research. A novel indicator based on SFE namely effective adhesion work is proposed to assess the asphalt-aggregate adhesion with different moisture contents. Then, given the mixing procedure of dry mixing method, an advanced three-phase model as form of asphalt-aggregate-warm mixing additive is introduced improving from the conventional two-phase asphalt-aggregate model for better reflecting the separate addition of warm mixing additive during mixing. Afterwards, the influence of aggregate types, asphalt type, aggregate moisture contents, warm-mixing agent types and warm-mixing process on the moisture susceptibility of WMA is analyzed utilizing the models and indicators proposed. Finally, the validity of the SFE indicator is verified by comparing the calculation of effective adhesion work with freeze-thaw splitting test result. The results show that all of the above factors impact the moisture susceptibility of WMA by influencing the interfacial adhesion, with the effect of moisture content being the most significant. Meanwhile, effective adhesion work and the three-phase model brought out in this research are proven to be feasible to characterize the adhesion properties of WMA, offering theoretical support to the research on warm mixing technology.

This thesis presents the effects of work done on a software project for generative models and spreadsheets, allowing for a quick creation of the conceptual model of the aircraft. The subject of the work is a response to the current trends and needs prevailing in the field of computer design engineering CAD and aviation. In the initial chapters, theoretical issues related to the work being carried out were introduced and the methodology of creating software for construction and verification of the structure of aircraft along with the needs of interchange between databases of generative models was presented. In the next stages, the concepts and selected solutions for the user interface supporting the knowledge base were presented along with a set of procedures for its operation. Furthermore, the method of database integration with the methods of determining design features for the developed generative models and with the Siemens NX system. Furthermore, problems encountered in software development, as well as solution examples for model application are specified. The results obtained and the models generated on their basis were subjected to a strength analysis using Autodesk Inventor software and analysed in terms of meeting the initial assumptions. In the end, conclusions and observations resulting from the effects of the work presented in the project were formulated.

Conservation of tropical endemic amphibians largely suffers from Wallacean shortfall, a gap to which predictive species distribution models have contributed significantly to bridge by delineating probable distribution and the underlying suitable habitat within their distributional range. However, rarely is a prediction model ground-truthed to evaluate their predictive performance. Here we present a species distribution modeling approach using maximum entropy algorithm corrected for smaller sample size, in guiding explorative surveys aimed at optimizing survey effort and discovering unrecorded populations of Zhangixalus suffry, a rhacophorid tree-frog endemic to the northeastern part of the Indian subcontinent along with the factors limiting their distribution. With only 16 established historical locality data to model for (after spatial thinning to reduce autocorrelation) and a set of environmental predictors (climatic, topographic, and landscape composition), our model prediction enabled the successful discovery of seven new population records from unreported landscapes, extending its southernmost distributional limit over a considerable distance. The final composite distribution model combining all the locality records (n=23) predicted similar core areas of suitable habitat consistent with the known geographic distribution of the species but showed poor representation under existing coverage of Protected Area (PA) network in the Region with only 7% representation of suitable habitat under protection. Habitat suitability of a site was significantly governed by factors related to precipitation (precipitation seasonality and precipitation of the warmest quarter) and topographic factors that can influence it (elevation and aspect). This corroborates with the known ecology of Rhacophorid frogs, especially concerning their seasonal explosive reproductive strategy and foam nest-building behavior.Through this study, we propose explorative surveys guided by species distribution models to expedite unknown population discovery of rare, tropical endemic amphibians and using such taxa as surrogates in identifying conservation priority zones that can be directly applied to reserve design and conservation and management planning.

Accurate evaluation of health status of lithium-ion batteries must be deemed as of great significance, insofar as utility and safety of batteries are of concern. Lithium plating, in particular, is notoriously known to be a chemical reaction that can cause deterioration in, or even fatal hazards to, the health of lithium-ion batteries. Electrochemical impedance spectroscopy (EIS), which has distinct advantages such as fast or non-destructive over its competitors, suffices in detecting lithium plating and thus has been attracting increasing attention in the field of battery management, but its ability of assessing quantitatively the degree of lithium plating remains largely unexplored hitherto. On this point, this work seeks to narrow that gap, by proposing an EIS-based method that can quantify the degree of lithium plating. The core conception is to eventually circumvent the reliance on state-of-health measurement, and use instead the impedance spectrum, to acquire an estimate on battery capacity loss. To do so, the effects of solid electrolyte interphase formation and lithium plating on battery capacity must be first decoupled, so that the mass of lithium plating can be quantified. Then, based on an impedance spectrum measurement, the parameters of the fractional equivalent circuit model (ECM) of the battery can be identified. These fractional ECM parameters are received as inputs by an artificial neural network, which is tasked to establish a correspondence between the model parameters and the mass of lithium plating. The empirical part of the work revolves around the data collected from an aging experiment, and the validity of the proposed method is truthfully attested by dismantling the batteries, which is otherwise not needed during the actual uptake of the method.

This article presents a forecast model that uses a hybrid architecture of recurrent neural networks (RNN) with surface neural networks (ANN), based on historical records of exported active energy (EAE) and weather data. Two types of models were developed: the first type includes six models that use EAE records and weather variables as inputs, while the second type includes eight models that use only weather variables. Different metrics were applied to assess the performance of these models, and the best model of each type was selected. Finally, a comparison of the performance between the selected models of both types is presented, and they are validated with real data provided by a solar plant, achieving acceptable levels of accuracy. The selected model of the first type has an RMSE of 0.19, MSE of 0.03, MAE of 0.09, a correlation coefficient of 0.96, and a determination coefficient of 0.93. The other selected model of the second type showed lower precision in the metrics (RMSE = 0.24, MSE = 0.06, MAE = 0.10, Corr. Coef. = 0.95, and Det. Coef. = 0.90). Both models demonstrated good performance and acceptable accuracy in forecasting the weekly photovoltaic energy production of the solar plant.

Non-alcoholic steatohepatitis (NASH), which is the most severe manifestation of non-alcoholic fatty liver disease (NAFLD), has been recognized as a major hepatocellular carcinoma (HCC) catalyst. However, the molecular mechanism of NAFLD-NASH-HCC sequence remains unclear and a specific and effective treatment for NASH has not yet been established. The progress in this field depends on the availability of reliable preclinical models which show the steady progress to NASH, liver cirrhosis, and HCC. However, most of NASH mouse models that have been described to date develop NASH generally for more than 24 weeks and there is an uncertainty of HCC development. To overcome such shortcomings of experimental NASH studies, we established a novel NASH-HCC mouse model with very high reproducibility, generality, and convenience. We treated male C57BL/6J mice with a newly developed choline-deficient and methionine-restricted high-fat diet (CDMRHFD) for 60 weeks. Treatment of CDMRHFD for 3 weeks revealed marked steatosis, lobular inflammation, and fibrosis, histologically diagnosed as NASH. Liver cirrhosis was observed in all mice with 36-week treatment. Liver nodule emerged at 12 weeks of the treatment, and diameter >2 mm liver tumors developed in all mice at 24 weeks of the treatment. In conclusion, our rapidly progressive and highly reproducible NASH-liver cirrhosis-HCC model is helpful for preclinical development and research on the pathogenesis of human NAFLD-NASH-HCC. Our mouse model would be useful for the development of novel chemistry for NASH-HCC-targeted therapies or HCC prevention strategies.

The present work is a numerical simulation of velocity and mixture fraction fields in a turbulent non-reaction Propane jet flow issuing into parallel co-flowing air, in isothermal condition which has been experimentally described here: http://www.sandia.gov/TNF/DataArch/ProJet.html. The objective is a better understanding of the flow structure and mixing process, a situation in which there is no chemical interaction and heat-transfer. The two-equation Realizable k-ε eddy viscosity turbulence model has been used to simulate the turbulent flow field on a 2D plane (i.e., on a 5-degree sector of the experimental domain), because Realizable k-ε more accurately predicts the spreading rate of both planar and round jets and presents the best proficiency in comparison with all versions of the k-ε models. Afterward, axial and radial profiles of mean velocities, turbulence energy, mean mixture fraction, the mixture fraction half radius (Lf), and the mass flux diagram have been numerically elicited for grid independent mesh (mesh B) and compared with corresponding experimental data to assess the numerical model. To obtain turbulence kinetic energy, k, due to lack of w' in the experimental data, the assumption of w'=v' seems to be valid. Simulations have demonstrated that mean mixture fraction (at radial profiles at locations x/D=0, 4, 15, 30 and 50) and its half radius, Lf, which characterizes jet width expanse, are prominently well-captured; Moreover, mean vertical velocity fields (in X-direction: Umean) have revealed less accuracy but still conspicuously well-captured. However, mean vertical velocity fields (in Y-direction: Vmean) have disclosed less resolution; Likewise, turbulence kinetic energy, k, have manifested moderate accuracy (between Umean and Vmean). It should be noticed that although numerical results for absolute pressure, p, have been obtained on aforementioned sections, there were no experimental data to compare with them. Thus, the corresponding numerical data has not been demonstrated in this study.

Global models have been developed to tackle the challenge of forecasting sets of series that are related or share similarities, but not for heterogeneous datasets. Various methods of partitioning by relatedness have been introduced to enhance the similarities of the set, resulting in improved forecasting accuracy but often at the cost of a reduced sample size, which could be harmful. To shed light on how the relatedness between series impacts the effectiveness of global models in real-world demand forecasting problems we perform an extensive empirical study using the M5 competition dataset. We examined cross-learning scenarios driven by the product hierarchy commonly employed in retail planning, which allow global models to capture interdependencies across products and regions more effectively. Our findings show that global models outperform state-of-the-art local benchmarks by a considerable margin, indicating that they are not inherently more limited than local models and can handle unrelated time series data effectively. The accuracy of data partitioning approaches increases, as the size of the data pools and the models' complexity decrease. However, there is a trade-off between data availability and data relatedness. Smaller data pools lead to increased similarity among time series, making it easier to capture cross-product and cross-region dependencies, but this comes at the cost of a reduced sample, which may not be beneficial. Finally, it's worth noting that the successful implementation of global models for heterogeneous datasets can significantly impact forecasting practice.

Malaria is a critical fevered illness caused by Plasmodium parasites transmitted among people through the bites of infected female Anopheles mosquitoes. Public awareness about the disease is important for the control of disease. This article proposes a mathematical model to study the dynamics of malaria disease transmission with the influence of awareness-based control interventions. We found two equilibria of the model, namely the disease-free and endemic equilibrium. Disease-free equilibrium is stable globally if basic reproduction number (R0) is less than unity (R0&lt;1). Some basic mathematical properties of the proposed model, such as nonnegativity and boundedness of solutions, the feasibility of the equilibrium points and their stability properties, have been studied. Finally, we adopted optimal control to minimize the cost of disease control and solve the problem by formulating Hamiltonian functional. The optimal use of insecticides for controlling the mosquito population is determined. Numerical simulations have been provided for the confirmation of the analytical results. We conclude that media awareness with optimal control approach is best for cost-effective malaria disease management.

This paper presents four key results in the philosophy of language. Firstly, it distinguishes between partial and consistent assertion of a sentence, and introduces the concept of an equivocal sentence, which is both partially asserted and partially denied. Secondly, it proposes a novel definition of truth, stating that a true sentence is one that is consistently asserted. This definition avoids the Liar paradox, does not restrict classical logic, and applies to declarative sentences in the language used by any particular person. Thirdly, the paper introduces an epistemic model of language, called assertional language, which formalizes the definition of truth. Finally, it provides an argument for the falsity of so-called Liar sentences. The proposed definition of truth can be viewed as a formal account of the correspondence theory. The epistemic model is a powerful concept that allows for combining different languages in a meaningful way. This model is uniquely capable of reflecting on epistemic inconsistencies, such as logical paradoxes, in a consistent manner and without resorting to non-classical solutions.

As a rapidly growing coastal megacity, Shanghai is continuously threatened with land subsidence issues since 1920s. Land subsidence was controlled in 1960s, however in 1990s, unconscious and dangerous urban underground space (UUS) exploration and tunneling development are causing further land subsidence. It is imperative to study previous relations towards future adaptive and resilient scenario modelling and planning. There are multiple cause-effect factors determined in the urban built environment of Shanghai megacity. This paper presents the current evidence based on the relations of the multifactor of the spectrum. Methods consist of understanding the cause-effect relations and spatiotemporal from the crucial period of 1960-2020. Data are collected secondarily from multiple open sourced databases. The results determine Shanghai are highly influenced by the UUS development induced-subsidence, tunneling leakage and weak spatial modelling. Spatiotemporal pattern has shown a mixed positive-negative impact: population, land subsidence is growing in parallel distribution (positive) with tunneling leakage, construction of tunneling, metro system, UUS development, building price, reconstruction area, GDP growth, land price, arable land decrease and further tunnel settlement in Urban City Centre, Pudong New Area, Minhang, Baoshan and Songjiang districts. These results are useful for further adaptive and resilient scenario modelling and spatial planning.

There must exist a reformulation of quantum field theory, even at low energies, which does not depend on classical time. The octonionic theory proposes such a reformulation, leading to a pre-quantum pre-spacetime theory. The ingredients for constructing such a theory, which is also a unification of the standard model with gravitation, are : (i) the pre-quantum theory of trace dynamics – a matrix-valued Lagrangian dynamics, (ii) the spectral action principle of non-commutative geometry, (iii) the number system known as the octonions, for constructing a non-commutative manifold and for defining elementary particles via Clifford algebras, (iv) a Lagrangian with $E_8 \times E_8$ symmetry. The split bioctonions define a sixteen dimensional space (with left-right symmetry) whose geometry (evolving in Connes time) relates to the four known fundamental forces, while predicting two new forces, $SU(3)_{grav}$ and $U(1)_{grav}$. This latter interaction is possibly the theoretical origin of MOND. Coupling constants of the standard model result from left-right symmetry breaking, and their values are theoretically determined by the characteristic equation of the exceptional Jordan algebra of the octonions. The quantum-to-classical transition, precipitated by the entanglement of a critical number of fermions, is responsible for the emergence of classical spacetime, and also for the familiar formulation of quantum theory on a spacetime background.

Digital Elevation Model (DEM) is a representation of elevation data that represent terrain with or without overlaying objects of the Earth. It is the ideal and most widely used method for determining topography. DEMs are generated from various techniques such as traditional Surveying, Photogrammetry, InSAR, LiDAR, Clinometry and radargrammetry. It has been observed that mostly LiDAR-generated DEMs provide the best accuracy. The unavailability of LiDAR data in most of the region restricts global researchers from high-resolution and accurate DEMs. The recent launch of ICESat-2 with a 13m beam footprint and 0.7m pulse interval, promises elevations at high orbital precision. Its accuracy is of the order of few centimeters in complex topography, because of this ICESat-2 proves to be a good source to generate high-accuracy DEMs. ICESat-2 provides discrete photon data with elevations of points on the Earth’s surface. Traditional interpolation techniques tend to over-smooth the estimated space and still are unable to justify the complicated continuity in the topographical data. Machine learning algorithms are widely being used to extract patterns and spatial extent in geographic data. To estimate a DEM from ICESat-2 LiDAR point data, machine learning regression algorithms are implemented in this study. The present study has been performed for a plain region of Ghaziabad, Uttar Pradesh, India. Studies have shown that Cartosat-1 DEM V3 R1 product provides an accuracy of the order of 2m in predominantly plain regions, hence taken for this region. Current work focuses on comparing various regression-based machine-learning techniques to interpolate DEM from ICESat-2 data The RMSE of the interpolated DEM resulted from the Gradient Boosting Regressor, Random Forest Regressor, Decision Tree Regressor, and Multi-Layer Perceptron Regressor was 7.13m, 7.01m, 7.15m, and 3.76m, respectively when evaluated against the TANDEM-X DEM of the same region. The MLP Regressor is found to perform the best among the four algorithms tested.

Nowadays, frameworks and models are critical to enabling organizations to identify their current sustainability integration into business and to follow up on these initiatives over time. In this context, the maturity models offer a structured way of analyzing how a supply chain meets specific sustainability requirements and which areas demand attention to reach maturity levels. This study proposes a five-level maturity model to help supply chains identify their level of engagement with sustainability practices combining three perspectives: intra and inter-organizational sustainability practices, triple-bottom-line approach and critical areas for sustainability. All the steps followed in constructing the maturity model were based on a literature review, and case studies supported its improvement, application, and testing. The proposed model presents many advantages, such as being used as a self-assessment tool, a roadmap for sustainability behaviour improvement, and a benchmarking tool to evaluate and compare standards and best practices among organizations and supply chains.

In the extended scalar sector of the SMASH (Standard Model - Axion - Seesaw - Higgs portal inflation) framework, we conduct a phenomenological investigation of the observable effects. In a suitable region of the SMASH scalar parameter spaces, we solve the vacuum metastability problem and discuss the one-loop correction to the triple Higgs coupling, $\lambda_{HHH}$. The $\lambda_{HHH}$ and SM Higgs quartic coupling $\lambda_H$ corrections are found to be proportional to the threshold correction. A large $\lambda_{HHH}$ correction ($\gtrsim 5 \%$) implies vacuum instability in the model and thus limits the general class of theories that use threshold correction. We performed a full two-loop renormalization group analysis of the SMASH model. The SMASH framework has also been used to estimate the evolution of lepton asymmetry in the universe.

A low-resource emotional speech synthesis system for empathetic speech synthesis based on modelling prosody features is presented here. Secondary emotions, identified to be needed for empathetic speech, are modelled and synthesised in this paper. As secondary emotions are subtle in nature, they are difficult to model compared to primary emotions. They are also less explored, and this is one of the few studies that model secondary emotions in speech. Current speech synthesis research uses large databases and deep learning techniques to develop emotion models. There are many secondary emotions, and hence, developing large databases for each of the secondary emotions is expensive. This research presents a proof-of-concept using hand-crafted feature extraction and modelling of these features using a low resource-intensive machine learning approach, thus creating synthetic speech with secondary emotions. Here, a quantitative model-based transformation is used to shape the emotional speech fundamental frequency contour. Speech rate and mean intensity are modelled via rule-based approaches. Using these models, an emotional text-to-speech synthesis system to synthesise five secondary emotions - anxious, apologetic, confident, enthusiastic and worried is developed. A perception test to evaluate the synthesised emotional speech is also conducted.

Physiologically Based Pharmacokinetic Models (PBPK) are mechanistical tools generally employed in the pharmaceutical industry and environmental health risk assessment. These models are recognised by regulatory authorities for predicting organ concentration-time profile, pharmacokinetic and daily intake dose of xenobiotics. Extension of PBPK models to capture sensitive populations like pediatric, geriatric, pregnant females, fetus etc. and diseased population like renal impairment, liver cirrhosis etc. is a must. However, the current modelling practice and existing models are not mature enough to confidently predict the risk in these populations. A multidisciplinary collaboration between clinicians, experimental and modeler scientist is vital to improve the physiology, and calculation of biochemical parameters for integrating the knowledge and refining existing PBPK models. Specific PBPK covering compartments like cerebrospinal fluid, and hippocampus are required to gain mechanistic understanding about xenobiotic disposition in these sub-parts. The PBPK model assists in building quantitative adverse outcome pathways (qAOPs) for several endpoints like developmental neurotoxicity (DNT), hepatotoxicity and cardiotoxicity. Machine learning algorithms can predict physicochemical parameters required to develop in-silico models where experimental data is unavailable. Integrating machine learning with PBPK carries the potential to revolutionize the field of drug discovery and development and environmental risk. Overall, this review tried to summarize the recent developments in the in-silico models, building qAOPs, use of machine learning for improving existing models along with a regulatory perspective. This review can act as a guide for toxicologists who wish to build their careers in kinetic modeling.

This study estimates the effects of double long memory and structural breaks on the persistence level of six major cryptocurrency markets. We apply the Bai and Perron’s structural break test, Inclán and Tiao’s iterated cumulative sum of squares (ICSS) algorithm, and the fractionally integrated generalized autoregressive conditional heteroscedasticity (FIGARCH) model with different distributions. The results show that long memory and structural breaks characterize the conditional volatility of cryptocurrency markets and confirm our hypothesis that ignoring structural breaks leads to an underestimation of the persistence of volatility modelling. The ARFIMA-FIGARCH model with structural breaks and a skewed Student–t distribution fits the cryptocurrency market’s price dynamics well.

Tuberculosis (TB) is still a worldwide major health problem and models using non-human primates (NHP) provide the most relevant approach for vaccine testing. In this study we have analysed CT images collected from cynomolgus and rhesus macaques, following exposure to ultra-low dose Mycobacterium tuberculosis (Mtb) aerosols, and monitored them for 16 weeks to evaluate the impact of prior intradermal or inhaled BCG-vaccination on the progression of lung disease. All lesions found (2553) have been classified according to their size and we have subclassified small micronodules (<4.4 mm) as ‘isolated’, or as ‘daughter’ when they are in contact with consolidation (described as lesions ≥ 4.5 mm). Our data links the higher capacity to contain Mtb infection in cynomolgus with the reduced incidence of daughter micronodules, thus avoiding the development of consolidated lesions and their consequent enlargement and evolution to cavitation. In the case of rhesus, intradermal vaccination has a higher capacity to reduce the formation of daughter. This study supports the ‘Bubble Model’ defined with the C3HBe/FeJ mice and proposes a new method to evaluate outcome in experimental models of TB in NHP based on CT images, which would fit a future machine learning approach to evaluate new vaccines.

In this paper mathematical analysis of the HIV/AIDS deterministic model exposed in [Espitia, C. et. al. Mathematical Model of HIV/AIDS Considering Sexual Preferences Under Antiretroviral Therapy, a Case Study in San Juan de Pasto, Colombia, Journal of Computational Biology 29 (2022) 483–493] is made. The objective is to gain insight into the qualitative dynamics of the model determining the conditions for the persistence or effective control of the disease in the community through the study of basic properties such as positiveness and boundedness, calculus of basic reproduction number, stationary points such as disease free equilibrium (DFE), boundary equilibrium (BE) and endemic equilibrium (EE) are calculated, local stability (LAS) of disease free equilibrium. It research allow to conclude that the best way to reduce contagion and consequently to reach a DFE is thought to be the reduction of homosexual partners rate as they are the most affected population by the virus, and are therefore the most likely to become infected and to spread the infection. Increasing the departure rate of infected individuals, leads to a decrease in untreated infected heterosexual men and untreated infected women.

With global warming, arable land in boreal regions is tending to expand into high latitude regions in the northern hemisphere. This entails certain risks; such that inappropriate management could result in previously stable carbon sinks becoming sources. Agroecological models are an important tool for assessing the sustainability of long-term management, yet applications of such models in boreal zones are scarce. We collated eddy-covariance, soil climate and biomass data to evaluate the simulation of GHG emissions from grassland in eastern Finland using the process-based model DNDC. We simulated gross primary production (GPP), net ecosystem exchange (NEE) and ecosystem respiration (Reco) with fair performance. Soil climate, soil temperature and soil moisture at 5 cm were excellent, and soil moisture at 20 cm was good. However, the model overestimated NEE and Reco following crop termination and tillage events. These results indicate that DNDC can satisfactorily simulate GHG fluxes in a boreal grassland setting, but further work is needed, particularly in simulated second biomass cuts, the (>20 cm) soil layers and model response to management transitions between crop types, cultivation, and land use change.

The passenger prediction flow is very significant to transportation sustainability. This is due to some chaos of traffic jams encountered by the road users during their movement to the offices, schools, or markets at earlier of the days and during closing periods. This problem is peculiar to the transportation system of the Federal University of Technology Minna, Nigeria. However, the prevailing technique of passenger flow estimation is non-parametric which depends on the fixed planning and is easily affected by noise. In this research, we proposed the development of a hybrid intelligent passenger frequency prediction model using the Auto-Regressive Integrated Moving Average (ARIMA) linear model, Convolutional Neural Network (CNN), and Kalman Filter Algorithm (KFA). The passengers’ frequency of arrival at the bus terminals is obtained and enumerated through the closed-circuit television (CCTV) and demonstrated using the Markovian Queueing Systems Model (MQSM). The ARIMA model was used for learning and prediction and compared the result with the combined techniques of using CNN-KFA. The autocorrelation coefficient functions (ACF) and partial autocorrelation coefficient functions (PACF) are used to examine the stationary data with different features. The performance of the models was analyzed and evaluated in describing the short-term passenger flow frequency at each terminal using the Mean Absolute Percentage Error (MAPE) and Mean Squared Error (MSE) values. The CNN-Kalman-filter model was fitted into the short-term series and the MAPE values are below 10%. The Mean Square Error (MSE) shows that the CNN-Kalman Filter model has the overall best performance with 83.33% of the time better than the ARIMA model and provides high accuracy in forecasting.

This work presents a nonlinear model predictive control scheme that challenges overcoming the obstacles holding back over decades to develop affordable autonomous control and monitoring systems applied in the large-scale industry. Among the numerous proposals in the literature, most do not consider the significant fluctuation of kinetic parameters in the reduced mathematical model ADM2, widely used for control and monitoring purposes. The prevalent cause, on a basis, is the lack of information caused by some dynamics and parameters that cannot be measured in real-time by reliable sensors. In addition, to make matters worse, those systems inherently act with nonlinear nature and have a high sensitiveness to uncontrollable inputs and perturbations. Therefore, to prevent these drawbacks, this work proposes a new methodology that reconstructs the lack of information from the non-measurable dynamics, concentration of bacterias, and the kinetic parameters related to reaction rates. Simulations results demonstrate the effectiveness of the methodology compared with traditional industrial control schemes.

Physics lacks a confirmed description of dark matter, has yet to develop an adequate understanding of dark energy, and includes unverified conjectures regarding new elementary particles. This essay features modeling that addresses those problems and explains otherwise unexplained data. Our modeling starts from five bases – multipole expansions for the electromagnetic and gravitational fields associated with an object, the list of known elementary particles, some aspects of mathematics for isotropic harmonic oscillators, concordance cosmology, and a conjecture that the universe includes six isomers of most elementary particles. The multipole expansions – which have use in conjunction with Newtonian kinematics modeling, special relativity, and general relativity – lead to a catalog of kinematics properties such as charge, magnetic moment, mass, and repulsive gravitational pressure. The multipole expansions also point to all known elementary particles, some properties of those particles, and properties of some would-be elementary bosons and elementary fermions. The harmonic-oscillator mathematics points to Gauge symmetries regarding some elementary bosons. The would-be elementary fermions lack charge and would measure as dark matter. The conjecture regarding six isomers of most elementary particles rounds out and dominates our specification for dark matter. Five of the isomers form the basis for most dark matter. Our modeling explains ranges of observed ratios of dark matter effects to ordinary matter effects – for the universe, galaxy clusters, two sets of galaxies observed at high redshifts, three sets of galaxies observed at modest redshifts, and one type of depletion of cosmic microwave background radiation. Our description of repulsive gravitational pressure points toward resolution for tensions – between data and modeling – regarding the recent rate of expansion of the universe, resolution for possible tensions regarding large-scale clumping, and resolution for possible tensions regarding interactions between neighboring galaxies. Our work regarding gravity, dark matter, and elementary particles suggests characterizations for eras that might precede the inflationary epoch, a mechanism that might have produced baryon asymmetry, mechanisms that govern the rate of expansion of the universe, and insight about galaxy formation and evolution.

This present work explores the performance of a thermal-magnetic engine of Otto type, considering as a working substance an effective interacting spin model corresponding to the q− state clock model. We obtain all the thermodynamic quantities for the q = 2, 4, 6, 8 cases in a small lattice size (3×3 with free boundary conditions) by using the exact partition function calculated from the energies of all the accessible microstates of the system. The extension to bigger lattices was performed using the mean-field approximation. Our results indicate that the total work extraction of the cycle is highest for the q=4 case, while the performance for the Ising model (q=2) is the lowest of all cases studied. These results are strongly linked with the phase diagram of the working substance and the location of the cycle in the different magnetic phases present, where we find that the transition from a ferromagnetic to a paramagnetic phase extracts more work than one of the Berezinskii–Kosterlitz–Thouless to paramagnetic type. Additionally, as the size of the lattice increases, the extraction work is lower than smaller lattices for all values of q presented in this study.

Ion-exchange membranes (IEMs) are widely used in desalination, waste water treatment, food, energy production and other applications. There is a strong demand for cost-effective IEMs characterized by high selective transport of ions of a certain sign of charge. In this paper, we simulate the experimental results of V. Sarapulova et al. (IJMS 2021) on the modification of an inexpensive anion-exchange membrane (CJMA-7, Hefei Chemjoy Polymer Materials Co. Ltd., China) with a perfluorosulfonated ionomer (PFSI). The modification was made in several stages including keeping the membrane at a low temperature, applying a PFSI solution on its surface, and subsequent drying it at an elevated temperature. We apply the known microheterogeneous model with some new amendments to simulate each stage of the membrane modification. It has been shown that the PFSI film formed on the membrane-substrate does not affect significantly its properties due to the small thickness of the film (4 m) and similar properties of the film and substrate. The main effect is caused by the fact that PFSI material “clogs” the macropores of the CJMA-7 membrane, thereby blocking the transport of coions through the membrane. In this case, the membrane microporous gel phase, which has a high selectivity to counterions, remains the primary pathway for both counterions and coions. Due to the above modification of the CJMA-7 membrane, the coion (Na+) transport number in the membrane equilibrated with 1 M NaCl solution decreased from 0.11 to 0.03. Thus, the modified membrane becomes comparable in its transport characteristics with more expensive IEMs available on the market.

We provide methodology and numerical results for the Hattendorff differential equa- tion for the continuous time evolution of the variance of L(j)t , the loss at time t random variable for a multi-state process, given that the state at time t is j.

Blackcurrant juice (Ribes nigrum L.) was subjected to supercritical carbon dioxide (SCCD) at 10, 30 and 60 MPa for 10 min at 45°C as well as thermally treated at 45°C and 85°C for 10 min to determine the stability, antioxidant capacity (AC) and bioaccessibility (BAc) of vitamin C, total anthocyanins and their individual monomers. An in vitro gastrointestinal digestion model completed with dialysis was used to assess BAc. The use of SCCD at each of the pressures applied improved the stability of vitamin C, total anthocyanins, and AC before in vitro digestion. As a result of digestion, L-ascorbic acid was oxidized to L-dehydroascorbic acid, and finally, the total content of vitamin C, anthocyanins, and AC decreased. SCCD did not significantly improve the BAc of vitamin C and total anthocyanins. The highest BAc of vitamin C was noted in fresh juice (FJ) (40%) and after mild heat treatment at 45°C (T45) (46%). The highest BAc of total anthocyanins was also noted in the FJ (4.4%). The positive effect of the application of SCCD on the BAc of the delphinidin-3-O-glycosides was observed compared to T45 and thermal pasteurization at 85°C (T85). Moreover, cyanidins were generally more bioaccessible than delphinidins in all samples. AC after digestion was higher in SCCD samples compared to thermally treated measured using ABTS+• and DPPH• assays, whereas in dialysate similar trends were observed only for AC measured using the ABTS+• assay. This phenomenon was justified by the formation of individual metabolites detected by UPLC-PDA-MS / MS in the model experiment with delphinidin-3-O-rutinoside. The protocatechuic acid which is well known as a strong antioxidant was detected in the model experiment after digestion. Further research is needed to better understand the metabolic pathway of anthocyanins and the possible uses of SCCD to improve the health properties of fruit products.

The Mediterranean is one of the regions of the world where human-induced climate warming is expected to have large impacts on water and environmental resources. To predict shifts in the current climate system, more regional climate records, including seasonal-to-century scale variability spanning longer than the instrumental periods, are needed. To help fill this gap, we provide a reconstruction of autumn precipitation variations for the Central Pyrenees range since 1500 Common Era (CE) using the varved sediments of Lake Montcortès. To assess the suitability of the calcite sublayer width of the sediments of this lake as a proxy for precipitation anomalies, we performed an analysis and smoothing of the temporal structure of the width series, calibration of the new series with the available instrumental climate records, calculation of a transfer function and testing and comparison of the reconstructed series against available empirical data.The prediction model was statistically robust and showed that the climatic signal was captured in the calcite sublayers. The reconstruction provides the first estimations of regional autumn precipitation shifts in the Central Pyrenees at annual resolution, since 1500 CE. Pronounced interdecadal shifts in precipitation were noticeable; no increasing nor decreasing linear trends or periods of extreme precipitation events were identified. The reconstructed precipitation anomalies suggest a decrease in rainfall during the coldest phase within the coldest period of the Little Ice Age and also during the 20^th century, probably associated to current Global Warming. Correlations between autumn precipitation and the North Atlantic Oscillation, Western Mediterranean Oscillation and Southern Oscillation indices were weak to moderate. A potential relationship with the Atlantic Multidecadal Oscillation pattern is suggested. The reconstructed autumn precipitation trends are coherent with other palaeohydrological reconstructions in similar Mediterranean settings, and consistent at a regional level.

In the context of carbon emissions peak, environmental issues highlight the importance of the green economy, how does economic agglomeration release growth potential and enable the coordinated development of the economy and environment? There are few works of literature to analyze it within the framework of spatial economy. This paper constructs a theoretical model to clarify the influence mechanism of economic agglomeration on green total factor productivity (GTFP), and then uses a dynamic SDM model to test the theoretical hypothesis. This contribution has three main findings. First, there is a "U-shaped" curve relationship between economic agglomeration and GTFP, and the formation mechanism is that economic agglomeration has a threshold effect on the agglomeration externalities such as infrastructure sharing, knowledge spillover, and labor market upgrading. Second, the mismatch of industrial structure is an important reason that the economic agglomeration in this region has not produced an obvious spatial spillover effect on other regions; Relaxing restrictions on the concentration of economic activity to regional centers would contribute to the improvement of GTFP. Third, GTFP has the classic "snowball effect" in the time dimension, but has the obvious "warning effect" in the space and time dimension. Based on this, this paper believes that at the present stage, it is necessary to adapt to the layout of economic geography, promote the rational allocation of human resources in the territorial space, promote the coordination between economic agglomeration and the development goal of green economy, and at the same time, it is necessary to cultivate the cooperative linkage mechanism of green economy development and transformation among cities.

To achieve the near zero emission of wastewater in the flue gas desulfurization (FGD) system in coal-fired power plant and better utilize the exhaust heat from flue gas, a feasible technology of spraying FGD wastewater in the flue duct for evaporation is discussed in the present study. A full-scale influencing factor investigation on the wastewater droplet evaporation performance is established under the Eulerian-Lagrangian model numerically. The dominant factors, including the characters of wastewater droplets, flue gas and the spray nozzles were analyzed under different conditions, respectively. Considering the multiple factors and conditions in the process, a Least-Square support vector machine (LSSVM) model is introduced to predict the evaporation rate based on the numerical results. Conclusions are made that the flue gas temperature and droplet diameter are of great importance in the evaporation process. The spray direction of droplet parallel with the flue gas flow direction is profitable for the dispersion of droplet, resulting the maximal evaporation rate. A double-nozzle arrangement optimized with relatively small flow rate is recommended. The LSSVM model can accurately predict the evaporation rate using the numerical results with different conditions.