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Preprint ARTICLE | doi:10.20944/preprints202404.1135.v1

Microstructure and Texture Evolution in Cold‐Rolled and Annealed Oxygen‐Free Copper Sheets

Jing Qin, Xun Li, Dongsheng Wang, Chen Zhou, Tongsheng Hu, JingWen Wang, Youwen Yang, Yujun Hu

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: microstructure; texture; copper sheet; rolling reduction; annealing twin

Online: 17 April 2024 (11:57:56 CEST)

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Preprint REVIEW | doi:10.20944/preprints202401.1948.v2

CRISPR/CAS Genome Editing Technology: Implications And Challenges

Taha Nazir, Azharul Islam, Hameed A. Mirza, Sahar Radwan, Nida Taha

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: CRISPR-Cas technology; Endonuclease recycling; Genome Editing; Implications

Online: 12 April 2024 (08:41:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0630.v1

A Comparative Study of Indentation Size Effect Models for Different Materials

Peina Wang, Yu Gao, Peihuan Wang

Subject: Engineering, Other Keywords: Indentation size effect; Existing model; Hardness; Indentation depth

Online: 10 April 2024 (11:34:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0668.v1

Multi-elemental Characterization of Soils in the Vicinity of Siderurgical Industry: Levels, Depth Migration and Toxic Risk

Antoaneta Ene, Florin Sloată, Marina V. Frontasyeva, Octavian G. Duliu, Alina Sion, Steluta Gosav, Diana Persa

Subject: Environmental And Earth Sciences, Environmental Science Keywords: soils; siderurgy; metals; trace elements; contamination; INAA; toxic risk

Online: 10 April 2024 (06:47:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1742.v1

Quantitative Assessment and Impact Analysis of Land Surface Deformation in Wuxi Based on PS-InSAR and GARCH Model

Shengyi Zhang, Lichang Xu, Rujian Long, Le Chen, Shenghan Wang, Shaowei Ning, Fan Song, Linlin Zhang

Subject: Environmental And Earth Sciences, Environmental Science Keywords: PS-InSAR; Wuxi city; Surface volatility; Sentinel-1A; Groundwater level

Online: 29 March 2024 (05:28:11 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.1634.v1

Genomic Insight into the COVID-19 Severity in MAFLD Patients: A Single-Center Prospective Cohort Study

Mykhailo Buchynskyi, Valentyn Oksenych, Iryna Kamyshna, Olena Budarna, Oleksandr Kamyshnyi

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: MAFLD; liver disease; SNP; COVID-19; SARS-CoV-2; interferon

Online: 27 March 2024 (15:01:31 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints202403.1547.v1

Functional Integrity of Radical SAM Enzyme Dph1•Dph2 Requires Non-canonical Cofactor Motifs with Tandem Cysteines

Koray Ütkür, Klaus Mayer, Shihui Liu, Ulrich Brinkmann, Raffael Schaffrath

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Dph1• Dph2; radical SAM enzyme; iron sulfur cluster; cysteine ligands; eEF2; diphthamide modification; ADP-ribosylation; Saccharomyces cerevisiae

Online: 26 March 2024 (06:31:30 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.1281.v1

NaCl Modifies Biochemical Traits in Bacterial Endophytes Isolated from Halophytes: Towards Salinity Stress Mitigation Using Consortia

Jesús Adrián Barajas González, Yersain Ely Keller de la Rosa, Rogelio Carrillo González, Ma. del Carmen Angeles González-Chávez, María Eugenia Hidalgo Lara, Ramón Marcos Soto Hernández, Braulio Edgar Herrera Cabrera

Subject: Environmental And Earth Sciences, Soil Science Keywords: plant growth-promoting bacteria; solubilization; salinity; enzyme activity; organic acids; food safety; plant fitness.

Online: 21 March 2024 (13:54:42 CET)

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Preprint REVIEW | doi:10.20944/preprints202403.0932.v1

Micro(nano)plastics and their potential impact on human gut health: a narrative review

Carlo Covello, Federica Di Vincenzo, Giovanni Cammarota, Marco Pizzoferrato

Subject: Biology And Life Sciences, Other Keywords: digestive system; gut microbiota; human cells; intestinal toxicity; microplastics; mouse models; nanoplastics; plastic; polymers

Online: 15 March 2024 (14:39:01 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0777.v1

Physical Experimental Study on the Wave Reflection and Run-Up of a New Ecological Hollow Cube

Haitao Zhao, Feiyue Ding, Junwei Ye, Huabing Jiang, Wei Chen, Weifang Gu, Gengfeng Yu, Qiang Li

Subject: Engineering, Other Keywords: Innovative armor block; hollow cube; wave run-up; wave reflection; design; physical model experiment

Online: 13 March 2024 (14:10:22 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.1522.v1

Mapping Dissolved Organic Carbon (DOC) and Organic Iron by Comparing Deep Learning and Linear Regression Techniques Using Sentinel 2 and WorldView 2 Imagery (Byers Peninsula, Marine Antarctica)

Susana del Carmen Fernández, Rubén Muñiz, Juanjo Peón, Ricardo Rodríguez-Cielos, Jesús Ruíz, Javier F. Calleja

Subject: Environmental And Earth Sciences, Ecology Keywords: maritime antarctica; dissolved organic carbon; organic iron; soil mapping; linear regression; deep learning; Sentinel2 images; WordView 2 imagery

Online: 27 February 2024 (13:28:44 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.1420.v1

Characterization and Simulation of the Interface between a Continuous and Discontinuous Fiber Reinforced Thermoplastic by Using the Climbing Drum Peel Test Considering Humidity

Nicolas Christ, Benedikt M. Scheuring, Christoph Schelleis, Wilfried V. Liebig, John Montesano, Kay A. Weidenmann, Jörg Hohe

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: Carbon fibers; Polyamide 6; Layered structures; Delamination; Cohesive interface modeling; Mechanical testing; Continuous-Discontinuous FRP

Online: 26 February 2024 (11:46:50 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.1284.v1

Resistance and Co-resistance of Metallo-Beta-Lactamase Genes in Diarrheal and Urinary Tract Pathogens in Bangladesh

Ayasha Siddique Shanta, Nahidul Islam, Mamun Al Asad, Kakoli Akter, Marnusa Binte Habib, Md. Jubayer Hossain, Shamsun Nahar, Brian Godman, Salequl Islam

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Bangladesh; Metallo-beta-lactamase; bla-NDM-1; bla-VIM; antimicrobial resistance; co-resistance; diarrhea, urinary tract infections; antimicrobial stewardship programs

Online: 22 February 2024 (08:48:08 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.1202.v1

Modern River-Sand Geochemical Mapping in the Manufahi Municipality and its Surroundings, Timor-Leste: Implications for Provenance

Vital Cruz Malai Araujo Vilanova, Tomoyuki Ohtani, Satoru Kojima, Kazuma Yatabe, Nene Valente Soares Cristovao, Aniceta Araujo

Subject: Environmental And Earth Sciences, Geochemistry And Petrology Keywords: geochemical mapping; lithological mapping; river sands; principal component analysis; provenance; alteration; silicification; low-grade metamorphism; secondary mineral assemblage.

Online: 22 February 2024 (01:35:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints202401.1815.v3

Safety and Efficacy of Wharton's Jelly Connective Tissue Allograft for Rotator Cuff Tears: Findings from a Retrospective Observational Study

Albert Lai, Conrad Tamea, John Shou, Anthony Okaf, Jay Sparks, Renee Dodd, Crislyn Woods, Naomi Lambert, Orion Leiloni Schulte, Tyler Chadd Barrett

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: Rotator Cuff; Wharton’ s Jelly; Regenerative Medicine; Umbilical cord tissue

Online: 21 February 2024 (04:15:36 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.0681.v1

Cancer-associated Systemic Abnormality: A Novel Marker Panel for Early-stage Breast Cancer Characterization

Stefan Schreier, Prapaphan Budchart, Suparerk Borwornpinyo, Lakkana Adireklarpwong, Prakasit Chirappapha, Wannapong Triampo, Panuwat Lertsithichai

Subject: Medicine And Pharmacology, Pathology And Pathobiology Keywords: early-stage breast cancer; circulating tumor cells; rare cells, liquid biopsy; systemic cancer; cytomorphology

Online: 12 February 2024 (11:37:36 CET)

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Preprint REVIEW | doi:10.20944/preprints201702.0020.v1

Potential Modes of Intercellular Alpha-Synuclein Transmission

Dario Valdinocci, Rowan A. W. Radford, Sue Maye Siow, Roger S. Chung, Dean L. Pountney

Subject: Medicine And Pharmacology, Pathology And Pathobiology Keywords: alpha-synuclein; Parkinsons disease; dementia with Lewy bodies; multiple system atrophy; tunelling nanotube; glymphatic system; cell-to-cell spread

Online: 7 February 2017 (03:24:21 CET)

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Preprint ARTICLE | doi:10.20944/preprints201701.0054.v1

Land Suitability Assessment for Camelina (Camelina sativa L.) Development in Chile

Celián Román-Figueroa, Rodrigo Padilla, Juan Manuel Uribe, Manuel Paneque

Subject: Environmental And Earth Sciences, Environmental Science Keywords: bioenergy; Camelina sativa; energy crops; agro-climatic suitability; biodiesel

Online: 11 January 2017 (04:57:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints201611.0006.v4

New Method of Environmental Assessment and Monitoring of Cu, Zn, As, and Pb Pollution in Surface Soil Using Terricolous Fruticose Lichens

Yuri Sueoka, Masayuki Sakakibara, Sakae Sano, Yoshikazu Yamamoto

Subject: Environmental And Earth Sciences, Environmental Science Keywords: biomonitor; environmental assessment; elemental competition; bioconcentration factor

Online: 9 December 2016 (16:31:32 CET)

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Preprint ARTICLE | doi:10.20944/preprints201611.0133.v1

Growth Hormone (GH) and Rehabilitation Promoted Distal Innervation in a Child Affected from a Syndrome of Caudal Regression

Jesús Devesa, Alba Alonso, Natalia López, José García, Carlos Israel Puell, Tamara Pablos, Pablo Devesa

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: GH; syndrome of caudal regression; sacral agenesis; physiotherapy; neurogenic bladder; flaccid paraplegia

Online: 27 November 2016 (04:35:36 CET)

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Preprint ARTICLE | doi:10.20944/preprints202409.0783.v2

Characteristics of Patients with Newly Diagnosed High-Grade Advanced Ovarian, Fallopian Tube and Primary Peritoneal Cancer in 2018–2023 and the Impact of Molecular Diagnostics on the Chemotherapy in Clinical Practice

Sonja Millert-Kalińska, Małgorzata Stawicka-Niełacna, Lidia Tomczak, Dominik Pruski, Marcin Przybylski, Karolina Jaszczyńska-Nowinka, Grzegorz Poprawski, Radosław Mądry

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: high-grade ovarian cancer; OC; molecular diagnostics

Online: 31 October 2024 (10:44:09 CET)

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Preprint ARTICLE | doi:10.20944/preprints202410.1905.v1

Contribution Of Structure Learning Algorithms In Epidemiology: An Application In A Real-World Dataset

Helene Colineaux, Benoit Lepage, Pierre Chauvin, Chloe Dimeglio, Cyrille Delpierre, Thomas Lefevre

Subject: Public Health And Healthcare, Other Keywords: causal discovery; directed acyclic graph; graphical models; social epidemiology; structure learning; Bayesian network

Online: 24 October 2024 (10:39:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202410.1698.v1

BioFire® Joint Infection Panel for Samples Other Than Synovial Fluid

Nicola Benvenuto, Stefano Di Bella, Luigi Principe, Diego Luppino, Jacopo Conti, Venera Costantino, Manuela Di Santolo, Marina Busetti, Roberto Luzzati, Verena Zerbato

Subject: Medicine And Pharmacology, Clinical Medicine Keywords: Biofire Joint Infection panel; multiplex PCR panels; diagnosis; culture-based diagnosis; diagnostic microbiology

Online: 24 October 2024 (10:02:08 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202410.1460.v1

Effects of Basal Division of Posterior Pallial Amygdala on the Motor Behaviors in Pigeons Based on Transcriptome Analysis

Xinmao Tian, Zishi Wang, Chunzhi Yi, Yuhua Shi, Chongchong Jia, Xiujuan Li, Feng Jiang, Zhenlong Wang

Subject: Biology And Life Sciences, Life Sciences Keywords: Pigeons; Basal division of posterior pallial amygdala; Transcriptome; Motor regulation neuromechnisms

Online: 18 October 2024 (10:52:35 CEST)

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Preprint REVIEW | doi:10.20944/preprints202410.0964.v1

Unveiling Roles of Beneficial Gut Bacteria and Optimal Diets for Health: A Comprehensive Review

Suresh Kumar, Riya Mukherjee, Chung-Ming Chang, Pratibha Gaur, V. Samuel Raj, Ramendra Pati Pandey

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords:

Healthy gut bacteria; Phytochemicals; Prebiotic foods &; Probiotic foods

Online: 12 October 2024 (10:02:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.2010.v1

Ciprofloxacin Concentrations in Food Could Select for Quinolone Resistance in Enterobacteriaceae: An In Vivo Study in Galleria mellonella

Nele Panis, Zina Gestels, Dorien Van Den Bossche, Irith De Baetselier, Said Abdellati, Thibaut Vanbaelen, Tessa de Block, Sheeba Santhini Manoharan-Basil, Chris Kenyon

Subject: Biology And Life Sciences, Life Sciences Keywords: K. pneumoniae; ciprofloxacin; AMR; MSC (minimal selective concentration); G. mellonella; ADI (acceptable daily intake)

Online: 25 September 2024 (11:56:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.1169.v1

Changes in Race Performance during the Underwater Phases of a 200 m Bi-Fins Race Simulation after Application Respiratory Muscle Training – Case Study in the Current World Record Holder

Tomáš Michalica, Jakub Březnina, Marek Polach, Dennis Peter Born, Jiří Mališ, Zbyněk Svozil, Eva Kociánová

Subject: Public Health And Healthcare, Physical Therapy, Sports Therapy And Rehabilitation Keywords: Swim training; Video-analysis; Finswimming performance; Respiratory muscle training; Underwater phases

Online: 17 September 2024 (04:56:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0980.v1

Evaluation of an Automatic Signal Detection of In Situ Hybridization for Detecting HPV DNA in Cervical Tissue Derived from Patients with Cervical Intraepithelial Neoplasia

Marcin Przybylski, Sonja Millert-Kalińska, Mateusz de Mezer, Monika Krzyżaniak, Paweł Kurzawa, Jakub Żurawski, Robert Jach, Dominik Pruski

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Automatic signal detection; Automatic response field; FFPE; ISH; HPV DNA; CIN; SIL

Online: 12 September 2024 (11:37:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1721.v1

A Preliminary Experimental Study on Biodegradation of 3D Printed Samples from Biomass-Fungi Composite Materials

Yeasir Mohammad Akib, Caleb Oliver Bedsole, Al Mazedur Rahman, Jillian Hamilton, Fahim Khan, Zhijian Pei, Brian D. Shaw, Chukwuzubelu Okenwa Ufodike

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: 3D Printing; biomass-fungi; biodegradation; soil burial test; mycelium

Online: 23 August 2024 (11:45:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1637.v1

Investigating Drug Release and Antitumor Activity in Experimental MEC1 and RM1 Cell Lines Using Multifunctional Iron Oxide Nanoparticles

Nino Maisuradze, Shalva Kekutia, Jano Markhulia, Tamar Tsertsvadze, Vladimer Mikelashvili, Liana Saneblidze, Niko Chkhaidze, Zsolt Endre Horváth, Laszlo Almasy, Nunu Mitskevichi

Subject: Chemistry And Materials Science, Nanotechnology Keywords: nanoparticles; cancer therapy; doxorubicin; drug delivery; cell cultures

Online: 22 August 2024 (16:29:31 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0950.v1

Insights into the Replication Kinetics Profiles of Malaysian SARS-CoV-2 Variant Alpha, Beta, Delta, and Omicron in Vero E6 cell line

Zarina Mohd Zawawi, Jeevanathan Kalyanasundram, Rozainanee Mohd Zain, Adiratna Mat Ripen, Dayang Fredalina Basri, Wei Boon Yap

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: SARS-CoV-2; variants; replication kinetics; infectivity; mutations; cell culture adaptation

Online: 13 August 2024 (13:02:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0608.v1

The Association Between Self-Reported Long COVID Symptoms and COVID-19 Conspiracy Theories in Jordan, Kuwait, among Other Arab Countries

Malik Sallam, Kholoud Al-Mahzoum, Moudhi Ahmad Alenezi, Maryam Alsaeed, Fatmah Alsaeed, Noor Albayati, Sarah Alkhaldi, Rawan J. Obeidat, Muna Barakat

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: SARS-CoV-2; Long COVID; Post-COVID Condition; Long Haul COVID; PASC Post Acute Sequelae of COVID-19; COVID-19 Post-Acute Sequelae; COVID-19 Conspiracy Theories; Health Communication

Online: 8 August 2024 (17:30:36 CEST)

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Long COVID comprises persistent symptoms which extend beyond four weeks post-SARS-CoV-2 infection. The potential association between long COVID and the endorsement of COVID-19 conspiracy theories has not been explored, particularly in Arab countries where high endorsement of these theories has been reported. This study aimed to explore the association between endorsing COVID-19 conspiracy theories and the prevalence of self-reported long COVID symptoms among adults in Jordan and Kuwait in addition to other Arab countries. The study employed a cross-sectional design using an electronic self-administered survey in Arabic language. Recruitment utilized snowball sampling via social media and the survey was distributed in July 2024. The survey instrument included sections on demographic information, the history of COVID-19 infection, and vaccination status. Long COVID manifestations were assessed using a score reflecting the frequency and intensity of ten recognized long COVID symptoms with subsequent categorization into three categories: low, middle, and high. The beliefs in COVID-19 conspiracy theories were measured via a 5-point Likert scale across five items. The final study sample comprised 756 respondents, the majority of whom self-reported a history of confirmed COVID-19 diagnosis at least once (n = 493, 65.2%). The results indicated a neutral average attitude towards COVID-19 conspiracy theories (mean score = 15.18±4.64 out of 30.00). Participants with high conspiracy theories scores were significantly more likely to report high (aOR = 6.85, 95% CI: 2.90–16.13, p < 0.001) and middle long COVID symptoms (aOR = 2.82, 95% CI: 1.32–6.06, p = 0.008) compared to those with lower scores. Additional predictors of higher long COVID reporting included female sex and lower self-reported household income. Frequent COVID-19 infections and hospitalizations were also associated with higher long COVID symptom reporting. The study results revealed a significant correlation between the endorsement of COVID-19 conspiracy theories and the higher frequency and magnitude of long COVID symptom reporting. The findings also highlighted the influence of sociodemographic factors and COVID-19 infection history on long COVID reporting, which suggests that public health strategies should address these factors to mitigate long COVID challenges effectively.

Preprint ARTICLE | doi:10.20944/preprints202408.0500.v1

Angiographic Correlation of Angina Topography in Patients Presenting with Acute Myocardial Infarction (AMI) -Can the Location of Angina Predict the Site of Coronary Artery Occlusion? – The ACOLYTE Study

Kamal Sharma, Ashwati Konat, Poojan Prajapati, Kavya Darji, Shalin Rawal, Vatsa Bhavsar, Prahar Darji, Yashrajsinh Gohil, Masum Patel, Shubham Patel, Parjanya Bhatt, Yashvi Pethani, Stuti Shah, Hardik Desai

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: Chest Pain; Angina; Acute Coronary Syndrome; Angina Topography; STEMI; NSTEMI

Online: 7 August 2024 (10:34:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.2206.v1

Study of the Features of Coating Deposition on a Carbide Substrate Using Preliminary Etching with Glow Discharge Plasma

Sergey Grigoriev, Marina Volosova, Yuri Bublikov, Catherine Sotova, Filipp Milovich, Ilya Shmakov, Alexey Vereschaka

Subject: Chemistry And Materials Science, Ceramics And Composites Keywords: glow discharge; coatings; surface preparation; ion bombardment; metal-cutting

Online: 29 July 2024 (07:09:02 CEST)

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Preprint REVIEW | doi:10.20944/preprints202407.1976.v1

Sildenafil Citrate Oral Suspension: A Systematic Review and Expert Opinion

Carlos Miacola, Luca Boeri, Fabrizio Palumbo, Carlo Ceruti, Davide Arcaniolo, Marco Bitelli, Giorgio Piubello, Chiara Polito, Tommaso Cai, Alessandro Palmieri

Subject: Medicine And Pharmacology, Urology And Nephrology Keywords: erectile dysfunction; phosphodiesterase-5 inhibitors; sildenafil

Online: 24 July 2024 (14:17:23 CEST)

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Preprint REVIEW | doi:10.20944/preprints202406.1588.v2

The Interplay Between Multisystem Inflammatory Syndrome in Children, Interleukin 6, Microbiome, and Gut Barrier Integrity

Ali Zari, Elrashdy M. Redwan, Mikolaj Raszek, David Cowley, Altijana Hromić-Jahjefendić, Vladimir N. Uversky, Mark Fabrowski, Carlo Brogna, Marina Piscopo, Alberto Rubio-Casillas

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: MIS-C; IL-6; gut barrier dysfunction; zonulin levels; microbiome; SARS-CoV-2 bacteriophage behavior; Long COVID-19

Online: 28 June 2024 (08:07:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1678.v1

Ipsa Senectus Morbus Est? Approaching the Unmet Needs in Geriatric Depression: Results From a National Survey

Umberto Albert, Carmine Tomasetti, Raffaele Antonelli Incalzi, Alessandro Cicolin, Alessandro Padovani, Michela Zanetti, Giuseppe Maina

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: antidepressants; comorbidity; trazodone; psychiatry; neurology; geriatrics; elderly

Online: 25 June 2024 (09:29:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1725.v1

Ionosonde Measurements Comparison during an ICME- and a SIR/CIR-Driven Geomagnetic Storm over Europe

Kitti Alexandra Berényi, Loredana Perrone, Dario Sabbagh, Alessandro Ippolito, Carlo Scotto, Árpád Kis, Veronika Barta

Subject: Environmental And Earth Sciences, Space And Planetary Science Keywords: space weather; geomagnetic storms; ionosphere; ionospheric storm; ICME; SIR/CIR; ionosonde; Digisonde; rTEC; TIMED/GUVI

Online: 25 June 2024 (07:15:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1461.v1

Markers of Epithelial-Mesenchymal Transition and Mucinous Histology in Early-Onset Colorectal Cancer

Aleksandra Djikic Rom, Sandra Dragicevic, Radmila Jankovic, Sanja Radojevic Skodric, Predrag Sabljak, Velimir Markovic, Jovana Rosic, Goran Barisic, Aleksandra Nikolic

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: early-onset colorectal cancer; epithelial-mesenchymal transition; mucinous tumor

Online: 20 June 2024 (15:29:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0409.v1

Behavior of IL-6 and Its Soluble Receptor Complex during Different Waves of the COVID-19 Pandemic

Gaetano Di Spigna, Bianca Covelli, Maria Vargas, Roberta Di Caprio, Valentina Rubino, Carmine Iacovazzo, Filomena Napolitano, Giuseppe Servillo, Loredana Postiglione

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: COVID 19 -; Severe Acute Respiratory Syndrome CoronaVirus 2; IL6 - IL6 receptor complex

Online: 6 June 2024 (12:47:11 CEST)

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In late December 2019 a novel RNA beta-coronavirus was recognized as the causative agent of previously pneumonia cases of unknown origin. The virus was successively named Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) as well as the respiratory illness that it causes Coronavirus disease 19 (COVID-19) (1, 2). The global spread of SARS-CoV-2 and the thousands of deaths caused by COVID-19 led the World Health Organization (WHO) to declare a pandemic on 11 March 2020. To date, the world has paid a high toll in this pandemic in terms of human lives lost, economic repercussions and increased poverty. Indeed, even if most patients with COVID-19 are asymptomatic or experience mild self-limiting disease, 14% of them progress to severe disease and 5% to critical illness with complications, such as interstitial pneumonia, respiratory failure with acute respiratory distress syndrome (ARDS) and multiple organ dysfunction syndromes (MODS) (3). It is accepted that SARS-CoV-2 primarily affects the respiratory system, although other organs are also involved (4). The virus enters host cells by attaching its Spike like surface projections to the angiotensin-converting enzyme-2 (ACE2) receptor which is mainly expressed on alveolar epithelial cells and in nearly all human organs in varying degrees. Thus, although the central target of SARS-CoV-2 infection is the lung, the wide distribution of ACE2 receptors in other organs may lead to cardiovascular, gastrointestinal, kidney, liver, central nervous system and ocular damages that have to be closely monitored during the disease (5, 6). The virus then activates the innate and adaptive immune system resulting in a large number of cytokines release, known as “cytokine storm”, that is directly correlated with tissue injury and unfavourable prognosis of severe lung disease (7). In particular, interleukin (IL)-6 seems to plays an important role in driving this cytokine release so that its increased levels have been recognized as a hallmark inflammatory signature in sera of COVID-19 patients (8). IL-6 is a polyfunctional cytokine with both anti-inflammatory and pro-inflammatory properties which exerts its several functions through two main signal transduction pathways (9). In the classical signal transduction pathway, IL-6 binds to IL-6-trans membrane receptor (IL-6R) to form a complex that, then, binds to the trans membrane glycoprotein gp130, inducing its homo-dimerization and initiating intracellular signal transduction. This kind of signaling is limited to cells (hepatocytes, macrophages, neutrophils, T cells, etc.) that express IL-6R on their cell surface (10). Nevertheless, cells do not express IL- 6R, as stromal and epithelial cells, are able to still respond to IL-6 because the soluble form of the receptor (sIL-6R) binds to IL-6 in circle and then anchors to membrane gp130 receptor, initiating the trans-signaling pathway. For this reason, sIL-6R is able to increase the function of IL-6 and is considered the agonist form of its receptor. When the level of IL-6 increases, its effects are widely expressed because gp130 molecules are ubiquitous and, therefore, also present in cells without IL-6R in the membrane form. On the contrary, a soluble form of the glycoprotein 130 (sgp130) can complex with sIL-6R to prevent the sIL-6R from binding to the membrane-bound gp130. In this case sgp130 is able to decrease the function of IL-6 and is considered the antagonist form of IL-6 receptor system (11). Based on the central role of IL-6 in the inflammatory pathology of COVID-19 and the consistent association between elevated levels of the cytokine and severe disease outcomes found in the first phase of infection, we sought to analysis IL-6 and its soluble receptor complex behavior during the different waves of COVID-19 pandemic, in order to evaluate the possible differences which occur among them and to hypothesize if they might be used as prognostic markers of disease severity.

Preprint ARTICLE | doi:10.20944/preprints202406.0032.v1

Discovery of Benzisothiazolone Derivatives as Bifunctional Inhibitors of HIV-1 Reverse Transcriptase DNA Polymerase and Ribonuclease H Activities

Alondra Vázquez Rivera, Heather Donald, Mounia Alaoui-El-Azher, John J. Skoko, John S. Lazo, Michael A. Parniak, Paul A. Johnston, Nicolas Sluis-Cremer

Subject: Biology And Life Sciences, Virology Keywords: HIV-1; reverse transcriptase; polymerase; ribonuclease H; inhibitor; benzisothiazolone

Online: 3 June 2024 (07:56:06 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202405.2094.v1

Detection of Mesothelial-to-Mesenchymal Transition-Derived Carcinoma-Associated Fibroblasts in Primary Ovarian Carcinomas

Henar Tomero-Sanz, José Antonio Jiménez-Heffernan, María Concepción Fernández-Chacón, Ignacio Cristóbal-García, Ricardo Sainz de la Cuesta, Lucía González-Cortijo, Manuel López-Cabrera, Pilar Sandoval

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Ovarian cancer; primary tumor; mesothelial cells; carcinoma-associated fibroblasts; mesothelial-to-mesenchymal transition

Online: 31 May 2024 (08:10:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1836.v1

Study on the Safety Characteristics of Different Types of Pepper (Capsicum L.)

László Kosár, Zuzana Szabová, Richard Kuracina, Stefan H Spitzer, Miroslav Mynarz, Bohdan Filipi

Subject: Engineering, Safety, Risk, Reliability And Quality Keywords: dust explosion; pepper samples; explosion characteristics; explosion protection

Online: 28 May 2024 (11:29:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0402.v2

Wheat Yield Estimation using Machine Learning Method Based on UAV Remote Sensing Data

Shurong Yang, Lei Li, Shuaipeng Fei, Mengjiao Yang, Zhiqiang Tao, Yaxiong Meng, Yonggui Xiao

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: machine learning; yield prediction; data fusion; wheat; phenotyping

Online: 23 May 2024 (12:31:37 CEST)

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Accurate forecasting of crop yields holds paramount importance in guiding decision-making processes related to breeding efforts. This study focused on the application of multi-sensor data fusion and machine learning algorithms based on unmanned aerial vehicles (UAVs) in wheat yield prediction. Five machine learning (ML) algorithms namely random forest (RF), partial least squares (PLS), ridge regression (RR), K-Nearest Neighbor (KNN) and eXtreme Gradient Boosting Decision Tree (XGboost) were utilized for multi-sensor data fusion, and three ensemble methods including the second-level ensemble methods (stacking and feature-weighted) and the third-level ensemble method (simple average) for wheat yield prediction. The 270 wheat hybrids were used as planting materials under full and limited irrigation treatments. A cost-effective multi-sensor UAV platform, equipped with red–green–blue (RGB), multispectral (MS), and thermal infrared (TIR) sensors, was utilized to gather remote sensing data. The results revealed that the XGboost algorithm exhibited outstanding performance in multi-sensor data fusion, with the RGB+MS+Texture+TIR combination demonstrating the highest fusion performance (R2=0.660, RMSE= 0.754). Compared with the single ML model, the employment of three ensemble methods significantly enhanced the prediction accuracy of wheat yield. Notably, the third-layer simple average ensemble method demonstrated superior performance (R2 = 0.733, RMSE= 0.668 t ha-1). It significantly outperformed both the second-layer ensemble methods of Stacking (R2= 0.668, RMSE= 0.673 t ha-1) and feature-weighted (R2= 0.667, RMSE= 0.674 t ha-1), thereby exhibiting superior predictive capabilities. This finding demonstrated that the third-layer ensemble method not only augments the predictive ability of the model but also fine-tuned the accuracy of wheat yield prediction through the employment of simple average ensemble learning. Consequently, it offers a novel perspective for crop yield prediction and breeding selection.

Preprint ARTICLE | doi:10.20944/preprints202405.1313.v1

Neutralization and Binding Capability of SARS-CoV-2 Variants by/of IgG Antibodies of Early COVID-19 Convalescent Inactivated Sera based on Indirect ELISA

Behzad Hussain, Peizhe Zhao, Bo Yang, Xiaoxiong Li, Zhichao Zhang, Guoqiang Feng, Demei Zhang, Defen Lu, Changxin Wu

Subject: Biology And Life Sciences, Virology Keywords: SARS-CoV-2; neutralization; early COVID-19; convalescent sera; ELISA

Online: 21 May 2024 (08:47:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1073.v1

Zebrafish as a Model for Studying Age-Dependent Sarcopenia and Frailty

Paula Aranda-Martínez, Ramy K. A. Sayed, José Fernández-Martínez, Yolanda Ramírez-Casas, Yang Yang, Germaine Escames, Darío Acuña-Castroviejo

Subject: Biology And Life Sciences, Aging Keywords: zebrafish; aging; skeletal muscle; mitochondria; sarcopenia

Online: 16 May 2024 (11:55:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.0647.v1

Emerging Mutations of SARS-COV-2 in Kenya

Elius Mbogori, Kelvin Thiongo, Harrison Yunyang Deng, Caroline Gikunyu, Winfrida Cheriro, Stanslaus Musyoki, Richard Biegon, Damaris Matoke-Muhia, Kirtika Patel, Binhua Liang, Elijah Songok

Subject: Biology And Life Sciences, Virology Keywords: SARS-CoV-2; COVID-19; Spike protein; Epistasis; Reverse transcription; Pathogenesis; Vaccine efficacy; Complementary DNA; Reverse transcription-polymerase chain reaction

Online: 10 May 2024 (11:30:40 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202405.0291.v1

New Isomeric Dipyridothiazine Dimers — Synthesis, Structural Characterization and Cytotoxicity Screening

Emilia Martula, Beata Morak-Młodawska, Małgorzata Jeleń, Paulina Strzyga-Łach, Marta Struga, Katarzyna Żurawska, Anna Kasprzycka

Subject: Chemistry And Materials Science, Medicinal Chemistry Keywords: phenothiazines; diazaphenothiazines; 2D NMR; structural analysis; Way2Drug; cytotoxicity

Online: 6 May 2024 (12:33:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1424.v1

Distinguishing Drivers via Wearable Sensor Data and Machine Learning

Natalia Piaseczna, Rafał Doniec, Konrad Duraj, Szymon Sieciński, Marek Jędrychowski, Ewaryst Tkacz, Marcin Grzegorzek

Subject: Engineering, Bioengineering Keywords: driving; wearable sensors; electrooculography; inertial sensors; machine learning

Online: 23 April 2024 (11:54:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1448.v1

Protein Bioengineering of a Crucial Biopharmaceutical for Acute Lymphoblastic Leukaemia: Improving Toxicogical, Immune and Inflammatory Responses to Asparaginase

Grace Verónica Ruiz Lara, Tales Alexandre Costa-Silva, Jorge Javier Muso Cachumba, Johanna Cevallos-Espinel, Marina Gabriel Fontes, Mitla Garcia-Maya, Khondaker Miraz Rahman, CARLOTA OLIVEIRA RANGEL-YAGUI, Gisele Monteiro

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: E. coli asparaginase; bioengineer; leukaemia; nonclinical assays

Online: 22 April 2024 (18:07:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1380.v1

Integration of Marine Spatial Planning and Terrestrial Spatial Planning and Its Implementation in Spain

F. Javier Córdoba-Donado, Vicente Negro-Valdecantos, Gregorio Gómez-Pina, Juan J. Muñoz-Pérez, Luis J. Moreno-Blasco

Subject: Environmental And Earth Sciences, Other Keywords: Marine Spatial Planning (MSP); Terrestrial Spatial Planning (TSP); Integrated Spatial Planning (ISP); integration; climate change; Land-sea interaction, extreme events; disastrous hazards

Online: 22 April 2024 (10:16:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1329.v1

Factors Associated with Communities’ Satisfaction of Receiving Curative Care Administered by Community Health Workers in the Health Districts of Boussé and Boussouma in Burkina Faso, 2024

Hamed Sidwaya Ouedraogo, Abdoul-Guaniyi Sawadogo, Ahmed Kabore, Badra Ali Traore, Mamadou Traore, Massoudou Harouna Maiga, Marcella Valerie Zombre Sanon, Maxime Koine Drabo

Subject: Public Health And Healthcare, Primary Health Care Keywords: community health workers; community health care; quality; perception; Burkina Faso Faso

Online: 19 April 2024 (10:04:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1152.v1

Synthesis, Activity, Toxicity, and In Silico Studies of New Antimycobacterial N-alkyl Nitrobenzamides as Potential DprE1 Inhibitors

João Pedro Pais, Olha Antoniuk, David Pires, Tiago Delgado, Andreia Fortuna, Paulo J Costa, Elsa Anes, Luis Constantino

Subject: Chemistry And Materials Science, Medicinal Chemistry Keywords: Tuberculosis; nitrobenzamides; DprE; mycobacteria

Online: 17 April 2024 (11:50:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0784.v1

Dramatic Suppression of Lipogenesis and No Increase in Beta- Oxidation Are the Main Effects of Bergamot Flavonoids on Gene Expression in Fatty Liver Disease

Maddalena Parafati, Daniele La Russa, Antonella Lascala, Francesco Crupi, Concetta Riillo, Bartosz Fotschki, Vincenzo Mollace, Elzbieta Janda

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: flavonoids; hepatic steatosis; lipogenesis; Citrus Bergamia; gene profiling

Online: 11 April 2024 (09:32:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1058.v1

Mesothelioma Associated Fibroblasts Modulate the Response of Mesothelioma Patient Derived Organoids to Chemotherapy through Interleukin-6.

Mario Cioce, Veronica Gatti, Fabiana Napolitano, Noemi Maria Giorgiano, Andrea Marra, Giuseppe Portella, Alfonso Fiorelli, Francesca Pentimalli, Vito Michele Fazio

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Mesothelioma patient-derived organoids, PDO, IL-6, mesothelioma-associated fibroblasts; cocultures, cisplatin; pemetrexed; chemoresistance

Online: 18 March 2024 (15:17:01 CET)

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Background. Malignant pleural mesothelioma (MPM) is still a rather incurable disease. Many classes of compounds with various mechanisms of action have been tested in vivo and ex-vivo, with rather disappointing results. This is partly due to preclinical studies mostly performed in models that fail to recapitulate MPM complexity and do not retain the intra-tumor heterogeneity, a propelling force for tumor progression. Additionally, we and others have shown that, under stress-induced chemotherapy, profound rearrangements take place in MPM cultures to fuel the emergence of chemoresistant cell subpopulations. Thus, finding clinically actionable modulators of MPM resistance is still a very urgent need. Methods. Setup and propagation of patient-derived organoid cultures from MPM pleural effusions; flow cytometry-based validation of organoid cultures, isola-tion and propagation of mesothelioma-associated fibroblasts; co-cultures, Lu-minex-based Cytokine array, ELISA assay to quantitate IL-6 in the conditioned media, qRT-PCR to assess mRNA expression of cancer stem cell markers and fibroblast markers. Results. Organoid cultures were obtained from eight MPM patients by using specific growth media and conditions to propagate pleural effusion-derived cells. We proved that primary MPM specimens and serially passaged (mesothelio-ma-Patient-Derived-Organoids) mPDOs were cytologically similar, with the obtained mPDOs expressing mesothelial markers similarly to the originating specimen. As expected from a clinically relevant model, the size and number of mPDOs were altered, in a patient-specific way, when pharmacologically relevant doses of chemotherapy drugs were added. We derived Mesothelio-ma-Associated-Fibroblasts (MAFs) and the addition of MAFs, to various ratios, altered the response of the mPDOs to pemetrexed + cisplatin, toward a reduced sensitivity to the latter anticancer agents. Additionally, organoid formation and size were altered by MAF-conditioned media, and this correlated with increased expression of cancer stem cell markers. We showed increased levels of IL-6 in the media of the treated cocultures and showed that this latter was derived from the MAFs. Conclusions. Increased secretion of IL-6 by mesothelioma-associated fibroblasts (MAFs) contributes to the resistance of the MPM to therapy.

Preprint ARTICLE | doi:10.20944/preprints202403.0898.v1

Frilled Lizard Optimization: A Novel Nature-Inspired Metaheuristic Algorithm for Solving Optimization Problems

Ibraheem Abu Falahah, Osama Al-Baik, Saleh Alomari, Gulnara Bektemyssova, Saikat Gochhait, Irina Leonova, Om Parkash Malik, Frank Werner, Mohammad Dehghani

Subject: Computer Science And Mathematics, Data Structures, Algorithms And Complexity Keywords: Optimization; bio-inspired; metaheuristic; frilled lizard optimization; exploration; exploitation

Online: 15 March 2024 (08:55:47 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0507.v1

Parents’ Participation in Care during Neonatal Intensive Care Unit Stay in COVID-19 Era: A Quantitative Observational Study

Emanuele Buccione, Davide Scarponcini Fornaro, Damiana Pieragostino, Luca Natale, Adelaide D'Errico, Valentina Chiavaroli, Laura Rasero, Stefano Bambi, Carlo Della Pelle, Susanna Di Valerio

Subject: Public Health And Healthcare, Nursing Keywords: neonatal intensive care unit; parenthood; newborns; preterm; nurses

Online: 8 March 2024 (11:04:21 CET)

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Preprint ARTICLE | doi:10.20944/preprints202403.0278.v1

External Hoof Measurements of Untrimmed and Unshod Mules in Northern Thailand

Thawijit Phannithi, Aree Laikul, Watcharapol Pathomsakulwong, Porrakote Rungsri, Tawanhathai Apichaimongkonkun, Krisana Watchrarat, Worakij Cherdchutham

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: mule; hoof conformation; forelimbs; hoof balanced; Equus caballus x Equus asinus; hoof measurement

Online: 6 March 2024 (05:14:37 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.1670.v1

Understanding Microplastics Retention Efficiency and Sorption Dynamics in Porous Media

Hande Okutan, Çağdaş Sağır, Bedri Kurtuluş, Hasan Burak Özmen, Emrah Pekkan, Moumtaz Razack, Philippe Le Coustumer

Subject: Environmental And Earth Sciences, Environmental Science Keywords: microplastics; porous media; retention; transport; polyethylene; retention efficiency; numerical model; MT3DMS; MODFLOW

Online: 29 February 2024 (11:41:01 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.1568.v1

The Town Crier: a Use Case Design and Implementation for a Socially Assistive Robot in Retirement Homes

Ana Iglesias, Raquel Viciana, Jose Manuel Perez-Lorenzo, Karine Lan Hing Ting, Alberto Tudela, Rebeca Marfil, Malak Al-Qbilat, Antonio Hurtado, Antonio Jerez, Juan Pedro Bandera

Subject: Computer Science And Mathematics, Robotics Keywords: social robot; wellbeing; human-centred design; participatory design; human-robot interfaces

Online: 28 February 2024 (03:12:51 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.1159.v1

Effects of Gibberellic Acid on Soluble Sugar Content, Organic Acid Composition, Endogenous Hormone Levels, and Carbon Sink Strength in Shine Muscat Grapes during Berry Development Stage

Xiujie Li, Zhonghui Cai, Xueli Liu, Wu Yusen, Zhen Han, Guowei Yang, Shaoxuan Li, Zhaosen Xie, Li Liu, Bo Li

Subject: Biology And Life Sciences, Horticulture Keywords: Gibberellin; Grape; Soluble sugar; Organic acid; Sugar unloading; Sink strength

Online: 20 February 2024 (14:39:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.0587.v1

Novel Dry Powder of Hyaluronic Acid-Vancomycin Complex for Inhalation Useful on Pulmonary Infections Associated to Cystic Fibrosis

María Sol Magi, Yanina De Lafuente, Eride Quarta, María Celeste Palena, Perla Ardiles, Paulina Laura Páez, Fabio Sonvico, Francesca Buttini, Alvaro Jimenez-Kairuz

Subject: Chemistry And Materials Science, Other Keywords: Vancomycin inhalable; cystic fibrosis; polyelectrolyte-drug complex; hyaluronic acid; pulmonary infection

Online: 12 February 2024 (04:53:10 CET)

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Preprint REVIEW | doi:10.20944/preprints201703.0125.v1

Peptidylarginine Deiminases as Mediators of Microvesicular Release - Novel Therapeutic Interventions

Sigrun Lange, Sharad Kholia, Uchini Kosgodage, Mariya Hristova, John Hardy, Jameel M Inal

Subject: Medicine And Pharmacology, Pathology And Pathobiology Keywords: Extracellular vesicles (EVs); Peptidylarginine deiminases (PADs); Chlor-amidine (Cl-Am); cancer; neurodegeneration; deimination; cytoskeleton; induced pluripotent stem cells (iPSCs); histone H3; epigenetics

Online: 16 March 2017 (17:54:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints201703.0060.v1

Biomass-Derived, Interconnected and Reticular Carbon Microtubes Electrodes for Symmetric Capacitors

Nannan Wang, Ning Zhang, Wutao Wei, Shizhong Cui, Hongwei Hou, Guangshan Zhu, Weihua Chen, Liwei Mi

Subject: Chemistry And Materials Science, Inorganic And Nuclear Chemistry Keywords: elasticbiomass; tubular structure; interconnected porous carbon; electric double layer capacitance

Online: 13 March 2017 (08:01:13 CET)

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Preprint ARTICLE | doi:10.20944/preprints201612.0085.v1

Economic Driven Patterns of the Urban Environment

Anibal Gusso, Conrad Philipp, André Silva, John Boland, Leticia Lenz

Subject: Environmental And Earth Sciences, Environmental Science Keywords: thermal remote sensing; EKC theory; urban development

Online: 16 December 2016 (08:00:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints201608.0154.v1

Vegetation Structure and Carbon Stocks of Two Protected Areas Within the South-Sudanian Savannas of Burkina Faso, West Africa

Mohammad Qasim, Stefan Porembski, Dietmar Sattler, Katharina Stein, Adjima Thiombiano, Andre Lindner

Subject: Biology And Life Sciences, Ecology, Evolution, Behavior And Systematics Keywords: carbon stock assessment; protected areas; savannas; degradation; woody vegetation; West Africa

Online: 15 August 2016 (12:06:29 CEST)

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Savannas and adjacent vegetation types like gallery forests are highly valuable ecosystems contributing to several ecosystem services including carbon budgeting. Financial mechanisms such as REDD+ have provided an opportunity for developing countries to alleviate poverty through conservation of its forestry resources. For availing this opportunity carbon stock assessments are essential. Therefore, a research study at two protected areas i.e. Nazinga Game Ranch and Bontioli Nature Reserve, in Burkina Faso was conducted with the objective of assessing carbon Mg C ha-1 in aboveground biomass (AGB)dry of trees in different formations of the south-sudanian savanna in Burkina Faso, West Africa. Similarly analysis of various vegetation parameters was also conducted to understand the overall vegetation structure of these two protected areas. For estimating AGBdry, existing allometric equation for dry tropical woody vegetation types was used. The Importance Value Index (IVI) and Family Importance Value (FIV) were estimated through standard procedures. Various linear and non-linear regression analyses were conducted to test the relationships between carbon and other parameters such as DBH, height and basal area (BA). The results showed that both sites collectively contain mean carbon of 3.41 ± 4.98 Mg C ha-1. Amongst different vegetation types, gallery forests recorded the highest mean carbon of 9.38 ± 6.90 Mg C ha-1. The highest IVI of 115.56 at Nazinga Game Ranch was recorded for Anogeissus leiocarpa. Similarly, highest IVI of 98.59 was recorded for Mitragyna inermis at Bontioli Nature Reserve. The highest FIV was recorded for Combretaceae for both of the sites. To our knowledge, this was the first study conducted to assess the carbon stocks at the two protected areas in southern Burkina Faso. The study therefore was an attempt for addressing the knowledge gap particularly on carbon stocks of protected savannas. It could serve as a baseline for carbon stocks for future initiatives such as payment for environmental services and REDD+ at these areas.

Preprint REVIEW | doi:10.20944/preprints202410.0208.v1

The Efficacy of Food Bioactive Compounds in The Treatment of Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis

Damilola Ibirogba, Oluwagbemisola Olukogbe, Ebsitu Haile, Moses Asori, Stephen Engmann, Abdullahi Abdulraheem, Gabriel Edeh, Thomas Mergerssa, Fortune Effiong, Babatunde Olowu, Prettyossa Kusemwa, Ukamaka Okafor, Isaac Omulepu, Stanley Eneh, Taiwo Aderinola, Renuka Thami, Nduka Okwose

Subject: Biology And Life Sciences, Food Science And Technology Keywords: Silymarin; non-alcoholic fatty liver disease (NAFLD); non-alcoholic steatohepatitis (NASH); Meta-analysis; Food Bioactive Substances; Nutraceuticals; Polyphenols

Online: 2 October 2024 (16:34:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.0421.v1

Novel Drug-like HsrA Inhibitors Exhibit Potent Narrow-Spectrum Antimicrobial Activities against Helicobacter pylori

Javier Casado, Irene Olivan-Muro, Sonia Algarate, Eduardo Chueca, Sandra Salillas, Adrián Velázquez-Campoy, Elena Piazuelo, María F. Fillat, Javier Sancho, Ángel Lanas, Andrés González

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Helicobacter pylori; antimicrobial resistance; narrow-spectrum antibiotic; antibacterial target; response regulator; HsrA; Campylobacter jejuni

Online: 5 September 2024 (10:22:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.2401.v1

Staphylococcus aureus Stress Response to Bicarbonate Depletion

Elisa Liberini, Sook-Ha Fan, Arnold S. Bayer, Christian Beck, Jacob Biboy, Patrice François, Joe Gray, Katharina Hipp, Iris Koch, Andreas Peschel, Brigitte Sailer, Daniela Vollmer, Waldemar Vollmer, Friedrich Götz

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Staphylococcus aureus; bicarbonate transporter; MpsABC; cell wall; peptidoglycan; transcriptome

Online: 30 July 2024 (11:03:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0599.v1

Effects of ACE Mutations Associated with Alzheimer’s Disease on Blood ACE Phenotype

Olga V. Kryukova, Igor O. Islanov, Elena V. Zaklyazminskaya, Dmitriy O Korostin, Vera A. Belova, Valery V. Cheranev, Zhanna A. Repinskaia, Svetlana A. Tonevitskaya, Alexander G. Tonevitsky, Pavel A. Petukhov, Steven M. Dudek, Olga A. Kost, Denis V. Rebrikov, Sergei M. Danilov

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Angiotensin I-converting enzyme; mutations; conformational changes; blood ACE; screening; Alzheimer’s disease

Online: 11 June 2024 (08:02:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0451.v1

Hypertriglyceridemia- from Innocent Bystander to Independent Cardiovascular Risk Factor in Younger Prehypertensives

Josipa Josipovic, Ana Jelakovic, Bernardica Valent Moric, Vladimir Prelevic, Gorana Mirosevic, Hana Matijaca, Iva Ivanko, Nikola Bulj, Ivo Darko Gabric, Bojan Jelakovic

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: prehypertension; hypertriglyceridemia; uromodulin; cardiovascular risk

Online: 7 June 2024 (08:24:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201611.0126.v3

IQGAP1 in Podosomes/Invadosomes Is Involved in the Progression of Glioblastoma Multiforme Depending on the Tumor Status

Deborah Rotoli, Natalia Pérez-Rodríguez, Manuel Morales, María Del Carmen Maeso, Julio Ávila, Ali Mobasheri, Pablo Martín-Vasallo

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: IQGAP1; glioblastoma multiforme (GBM); scaffold protein; podosome/invadosome

Online: 16 January 2017 (10:30:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202410.1748.v1

Application of the Sponge Model Implants in the Study of Vaccine Memory in Mice Previously Immunized with LBSap

Mariana Ferreira Lanna, Lucilene Aparecida Resende, Paula Mello De Luca, Wanessa Moreira Goes, Maykelin Fuentes Zaldívar, André Tetzl Costa, Walderez Ornelas Dutra, Alexandre Barbosa Reis, Olindo Assis Martins-Filho, Kenneth Jhon Gollob, Sandra Aparecida Lima De Moura, Edelberto Santos Dias, Érika Michalsky Monteiro, Denise Silveira-Lemos, Rodolfo Cordeiro Giunchetti

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: sponge implant model; vaccine; immune response; mice

Online: 24 October 2024 (12:08:35 CEST)

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Considering the large number of candidates in vaccine testing studies against different pathogens and the amount of time spent in the pre- and clinical trials, there is a pressing need to develop an improved in vivo system to quickly screen vaccine candidates. The model of a polyester-polyurethane sponge implant provides a rapid analysis of the specific stimulus-response, allowing the study of a compartmentalized microenvironment. The sponge implant’s defined measurements were standardized as a compartment to assess the immune response triggered by vaccinal antigen. The LBSap vaccine (composed by Leishmania braziliensis antigens associated with saponin adjuvant) was used in the sponge model to assess the antigen-specific immunological biomarker, including memory generation after initial contact with the antigen. Mice strains (Swiss, BALB/c, and C57BL/6) were previously immunized using LBSap vaccine followed by an antigenic booster performed inside the sponge implant. The sponge implants were assessed after 72 hours, and the immune response pattern was analyzed according to leukocyte immunophenotyping and cytokine production. After LBSap vaccination, the innate immune response of the antigenic booster in the sponge implants demonstrated higher levels in the Ly+ neutrophils and CD11c+ dendritic cells with reduced numbers of F4/80+ macrophages. Moreover, the adaptive immune response in Swiss mice demonstrated a high CD3+CD4+ T-cells frequency consisting of an effector memory component in addition to a cytoxicity response (CD3+CD8+ T-cells), displaying the central memory biomarker. The major cell surface biomarker in the BALB/c mice strain was related to CD3+CD4+ effector memory while the increased CD3+CD8+ effector memory was highlighted in C57/BL6. The cytokine profile was more inflammatory in Swiss mice, with the highest levels of IL-6, TNF, IFN-g, and IL-17, while the same cytokine was observed in in C57BL/6 yet modulated by enhanced IL-10 levels. Similar to Swiss mice, BALB/c mice triggered an inflammatory environment after the antigenic booster in the sponge implant with the increased levels in the ILL-6, TNF, and IFN-g. The results highlighted how genetic background can influence populations involved in the immune response and indicated that it is possible to use this model to optimize and monitor the innate and adaptive immune responses of vaccine candidates. In this sense, these results could guide the choice of the most appropriate experimental model in biomolecule tests, considering that the particularities of each mouse strain influenced the dynamics of the immune response.

Preprint ARTICLE | doi:10.20944/preprints202409.0917.v1

Real Life Comparative Analysis of Robotic Assisted versus Laparoscopic Radical Prostatectomy in a Single Centre and Single Surgeon Experience

Stefano Salciccia, Valerio Santarelli, Giovanni Battista Di PIerro, Francesco Del Giudice, Giulio Bevilacqua, Giovanni Di Lascio, Alessandro Gentilucci, Roberta Corvino, Valentina Brunelli, Greta Basile, Carlo Maria Scornajenghi, Lorenzo Santodirocco, Luca Gobbi, Davide Rosati, Martina Moriconi, Valeria Panebianco, Fabio Massimo Magliocca, Daniele Santini, Mattia Alberto Di Civita, Flavio Forte, Marco Frisenda, Giorgio Franco, Alessandro Sciarra

Subject: Medicine And Pharmacology, Urology And Nephrology Keywords: prostatic neoplasm; radical prostatectomy; robotic surgery; laparoscopic surgery

Online: 12 September 2024 (11:01:00 CEST)

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Background: The advantage of a robotic assisted (RARP) over a laparoscopic (LRP) approach in radical prostatectomy (RP) remains to be demonstrated. Aim of the study is to use a homogeneous population in real life and single surgeon surgery, to analyze the oncological and functional results based on the type of the surgical approach. Methods: This is a prospective trial on non-metastatic prostate cancers (PC) patients considered after multidisciplinary decision to RP, using RARP or LRP. A real-life setting was analyzed at our Urological Departments, using homogeneous criteria for the management of PC cases and a one surgeon experience on 444 cases (284 LRP and 160 RARP) .Results: Mean operative time was significantly lower in RARP (173.33±44.3 min) than in LRP (153.21±25.1 min) (p<0.001). In cases submitted to an extended lymph node dissection (eLND), the mean number of lymph nodes removed was 15.16±7.83 and 19.83±4.78 respectively in LRP and RARP procedures (p<0.001), but positive lymph nodes (pN1) were similarly found in 15.8% of LRP patients and 13.6% of RARP patients (p=0.430). Surgical margins (SM) positivity was not significantly higher in RARP group (20.0%) when compared to LRP group (15.9%) (p=0.145). During the postoperative follow-up, a biochemical recurrence (BCR) was detected in 14.4% and 7.5% of cases in the LRP and RARP group respectively (p=0.014). Better results of PAD test at 3-month interval using RARP approach (mean pad weight 75.57±122 grams and 14±42 grams respectively in LRP and RARP (p<0.01)) were described. Conclusions: In the comparison between RARP and LRP approach, a clear advantage of the robotic approach is a significant reduction in operating times, days of hospitalization and postoperative catheterization compared to laparoscopic surgery. It is not possible to describe any certain oncological advantage both in terms of surgical margins and pathological lymph nodes removed. In RARP cases a reduction to the limit of significance is described in terms of biochemical recurrence. RARP produces a more rapid recovery of urinary continence at 3 months postoperatively without significant advantages in terms of erective potency recovery.

Preprint ARTICLE | doi:10.20944/preprints202404.1992.v1

N-Terminal Sequences of Signal Peptides Assuming Critical Roles in Expression of Heterologous Proteins in Bacillus subtilis

Meijuan Zhang, Jie Zhen, Jia Teng, Xingya Zhao, Xiaoping Fu, Hui Song, Yeni Zhang, Hongchen Zheng, Wenqin Bai

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: signal peptide; secretion; transcription; extracellular expression; N-terminal amino acids sequence; alkaline pectinase

Online: 30 April 2024 (10:18:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201607.0051.v1

Search for QPOs in the Light Curve of the Blazar OJ287: Preliminary Results from 2015/16 Observing Campaign

S. Zola, M. Valtonen, G. Bhatta, A. Goyal, B. Debski, A. Baran, J. Krzesinski, M. Siwak, S. Ciprini, A. Gopakumar, H. Jermak, K. Nilsson, D. Reichart, K. Matsumoto, K. Sadakane, K. Gazeas, M. Kidger, V. Piirola, F. Alicavus, K.S. Baliyan, A. Berdyugin, D. Boyd, M. Campas Torrent, F. Campos, J. Carrillo Gomez, D.B. Caton, V. Chavushyan, J. Dalessio, D. Dimitrov, M. Drozdz, A. Erdem, A. Escartin Perez, V. Fallah Ramazani, A.V. Filippenko, F. Garcia, F. Gomez Pinilla, M. Gopinathan, J.B. Haislip, J. Harmanen, G. Hurst, K.M. Ivarsen, M. Jelinek, A. Joshi, M. Kagitani, N. Kaur, N. Karaman, W.C. Keel, A.P. LaCluyze, B.C. Lee, E. Lindfors, J. Lozano De Haro, J.P. Moore, R. Naves Nogues, A.W. Neely, R.H. Nelson, W. Ogloza, S. Okano, J.C. Pandey, M. Perri, P. Pihajoki, G. Poyner, J. Provencal, T. Pursimo, A. Raj, R. Reinthal, S. Sadegi, T. Sakanoi, J.-L. Salto Gonzales, T. Schweyer, F.C. Soldan Alfaro, E. Sonbas, I. Steele, J.T. Stocke, J. Strobl, L.O. Takalo, T. Tomov, L. Tremosa Espasa, J.R. Valdes, J. Valero Perez, F. Verrecchia, J.R. Webb, M. Yoneda, M. Zejmo, W. Zheng, J. Telting, J. Saario, T. Reynolds, A. Kvammen, E. Gafton, R. Karjalainen, P. Blay

Subject: Physical Sciences, Astronomy And Astrophysics Keywords: galaxies: active; BL Lacertae objects: individual (OJ 287); super massive black holes

Online: 18 July 2016 (10:46:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202411.0124.v1

Evaluation of Fish Biosolids as a Growth Media Component for Organic Tomato Transplant Production

Cicely Schembri, Nicholas Kaczmar, John Osborn, Michael Ben Timmons, and Neil S. Mattson

Subject: Biology And Life Sciences, Horticulture Keywords: organic nutrients; tomato seedlings; supplementation; fertilizer; fish biosolids

Online: 4 November 2024 (11:05:50 CET)

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Preprint ARTICLE | doi:10.20944/preprints202410.2455.v1

Tennis Game Dynamic Prediction Model Based on Players’ Momentum

Lechuan Wang, Puning Chen

Subject: Computer Science And Mathematics, Probability And Statistics Keywords: tennis; momentum; quantification; match prediction; XGBoost

Online: 30 October 2024 (14:10:58 CET)

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Preprint ARTICLE | doi:10.20944/preprints202410.1483.v1

Quantitative Modeling in Systems Biology: How to Develop Relevant Models

Gülbahar Akgün, Rza Bashirov

Subject: Medicine And Pharmacology, Other Keywords: systems biology; quantitative modeling; Petri nets; descriptive statistics; spinal muscular atrophy

Online: 18 October 2024 (14:02:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202410.1207.v1

The Relationship of Sociodemographic Attributes and Financial Well-Being of Low-Income Urban Families Amid Covid-19 Pandemic: A Case of Malaysia

Abdullah Sallehhuddin Abdullah AbdullahSalim, Norzarina Md Yatim, Al Mansor Abu Said

Subject: Social Sciences, Sociology Keywords: financial well-being; low-income; families, urban poverty; COVID-19 pandemic; sociodemographic

Online: 15 October 2024 (13:33:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.2131.v1

Numerical Approach to Determine the Resistance of Threaded Anchors in UHPFRC

Antonina Hochuli, Eugen Brühwiler

Subject: Engineering, Architecture, Building And Construction Keywords: short anchorage; threaded anchor; numerical simulation; structural behavior; pull-out force

Online: 27 September 2024 (00:15:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202409.1990.v1

Deep Learning Models for White Blood Cell Image Classification

Noureldin Said Youssef, Omar Sameh Emam, Adel Said Elmaghraby

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: white blood cells; image classification; deep learning; machine learning; health informatics

Online: 25 September 2024 (12:09:03 CEST)

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Preprint REVIEW | doi:10.20944/preprints202409.0879.v1

Paradoxes in Telemedicine Services: Analysis of Challenges and Opportunities for the Future of Digital Health - A Systematic Literature Review

Faisal Binsar, Mohammad Hamsal, Ediansyah Ediansyah

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: paradox; telemedicine; health services; opportunities; challenges; digital health

Online: 11 September 2024 (10:02:51 CEST)

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Preprint REVIEW | doi:10.20944/preprints202408.1853.v1

Comprehensive Understanding of Recent Molecular and Physio-Biochemical Mechanisms in the Response of Tomatoes to Low Temperature Stress

Kwanuk Lee, Hunseung Kang

Subject: Biology And Life Sciences, Plant Sciences Keywords: low temperature (LT) response; cold stress; morphological and physiological traits; biochemical changes; C-repeat binding factor (CBF); RNA and DNA methylation; epigenetic regulations; climate change

Online: 27 August 2024 (11:54:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.1143.v1

Effect of the Localized Insecticides Spray Technique to Control Halyomorpha halys in Actinidia chinensis Orchards

Matteo Landi, Michele Preti, Antonio Masetti, and Francesco Spinelli

Subject: Biology And Life Sciences, Insect Science Keywords: brown marmorated stink bug; kiwifruit; integrated pest management; fruit damage; chemical control; atomizer; insecticide application

Online: 15 August 2024 (14:33:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202408.0443.v1

A Novel Hashcode-based Duplication Reduction via Thresholding Approach for Large-scale Web Documents

Sana Ejaz, Asma Naseer, asma Ahmad, maria Tamoor, Samina Naz

Subject: Computer Science And Mathematics, Computer Science Keywords: Duplicate detection; Hash keys; Information Retrieval; Threshold; Web documents; and Web pages

Online: 6 August 2024 (15:56:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.2006.v1

Study of the Feasibility of Multi-channel WDM Transmission Using RGB LEDs in Visible Light Communication

Véronique Georlette, Théo Deffrennes, Veronique Moeyaert

Subject: Engineering, Telecommunications Keywords: VLC; WDM; RGB; OOK; Raspberry Pi; OFDM

Online: 25 July 2024 (09:45:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.1300.v1

Parallel PSO for the Efficient Training of Neural Networks Using the GPGPU and Apache Spark in an Edge Computing Environment

Manuel I. Capel, Alberto Salguero-Hidalgo, Juan Antonio Holgado-Terriza

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Apache Spark; Classification recall; Deep Neural Networks; GPU Parallelism; Optimization research; Particle Swarm Optimization (PSO); Predictive Accuracy

Online: 16 July 2024 (08:29:08 CEST)

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Preprint REVIEW | doi:10.20944/preprints202407.0882.v1

Recent Advances in Phthalocyanine-Based Hybrid Composites for Electrochemical Biosensors

Keshavananda Prabhu Channabasavana Hundi Puttaningaiah, Jaehyun Hur, Shivalingayya Gaddimath

Subject: Chemistry And Materials Science, Electrochemistry Keywords: Biosensors; Phthalocyanine; Nanoparticles (NPs); Carbon nanomaterials; Hybrid Materials; Biomolecule Detection

Online: 10 July 2024 (14:09:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202407.0735.v1

Plan Time Management in School Activities and Relation to Procrastination: A Study for Educational Sustainability

Sabina Valente, Sergio Dominguez-Lara, Abílio Lourenço

Subject: Social Sciences, Psychology Keywords: ; academic procrastination; time management planning; gender; study hours; elementary education ;

Online: 10 July 2024 (04:54:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1722.v1

Economic Efficiency versus Energy Efficiency of Selected Crops in EU Farms

Paweł Boczar, Lucyna Błażejczyk-Majka

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: agricultural resources; economic security of farmers; Europe’ s energy security; agricultural production efficiency; economics of land use

Online: 25 June 2024 (10:09:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.1363.v1

Application of the Transmutation Operator Method to the Solution of an Initial Boundary Value Problem for the Equation of Multidimensional Free Transverse Vibration of a Thin Elastic Plate Containing the Bessel Operator

Shakhobiddin Karimov, Yorkinoy Tulasheva

Subject: Computer Science And Mathematics, Mathematics Keywords: fourth-order equation; plate vibration equation; Bessel operator; transmutation operator; Erdélyi–Kober operator

Online: 19 June 2024 (15:02:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0825.v1

Development of Artificial Intelligence/Machine Learning (AI/ML) Models for Methane Emissions Forecasting in Seaweed

Clifford Jaylen Louime, Tariq Asleem Raza

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Methane Emission; Sargassum; Convolutional Neural Network (CNN); Environmental Impact Assessment; Artificial Intelligence; Machine Learning

Online: 12 June 2024 (17:41:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202406.0074.v1

Evolving HPC Data Centers with Kubernetes, Performance Analysis, and Dynamic Workload Placement Based on ML Scheduling

Vedran Dakić, Mario Kovač, Jurica Slovinac

Subject: Computer Science And Mathematics, Computer Science Keywords: high-performance computing; data center architecture; hardware and software integration; Kubernetes; dynamic performance evaluation ;

Online: 6 June 2024 (03:20:32 CEST)

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Preprint CASE REPORT | doi:10.20944/preprints202405.2167.v1

Adult-Onset Systemic Chronic Active Epstein - Barr virus Disease: A Case Report Highlighting Unique Immunophenotype and Novel Molecular Insights in the Context of Chronic HBV Hepatitis

Tulasi Geevar, Peter JB Sabatini, Tong Zhang, Ali Sakhdari

Subject: Medicine And Pharmacology, Pathology And Pathobiology Keywords: chronic EBV infection; T cell lymphoproliferative disorder; mutational profile

Online: 3 June 2024 (07:58:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.2091.v1

Occupational Accidents, Injuries, and Associated Factors among Migrant and Domestic Construction Workers in Saudi Arabia

Musaad Alruwaili, Patricia Carrillo, Robby Soetanto, Fehmidah Munir

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: construction industry; migrants; occupational accidents; occupational injuries; Saudi Arabia

Online: 31 May 2024 (08:49:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1941.v1

An Innovative n-Shifted Sigmoid Channel and Spatial Attention Module for Efficient 3D Scene Object Detection

Shengzhi Du, Desire Mulindwa Burume, Qingxue Liu

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: attention mechanism; Hough voting; point clouds; activation function

Online: 29 May 2024 (13:50:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202405.1148.v1

Method for Revealing the Violation of Synchronization in the Operation of Geomagnetic Observatories of Intermagnet Network

Ivan Veniaminovich Vassilyev, Zhassulan Korabayevich Mendakulov, Inna Nikolaevna Fedulina, Beibit Tenelovich Zhumabayev

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: Intermagnet; SuperMAG; ecliptic coordinate system; magnetic storms; violation of synchronization in operation of magnetic observatories; correlation; signal-to-noise ratio; SSC – storm sudden commence

Online: 17 May 2024 (11:36:30 CEST)

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Preprint REVIEW | doi:10.20944/preprints202405.0423.v1

Predictive Analytics Performance on Oil and Gas: A Significant Review

Putri Azmira R Azmi, Marina Yusoff, Mohamad Taufik Mohd Salledud-din

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: classification; clustering; machine learning; oil and gas; predictive analytics

Online: 8 May 2024 (09:05:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1881.v1

The Status of Food Insecurity at the Household Level in the North-Eastern Highlands of Ethiopia

Umar Demisse Mohammed, Arega Bazezew Berlie, Simachew Bantigegen Wassie

Subject: Social Sciences, Geography, Planning And Development Keywords: Livelihood zone; Households; Food insecurity status; South wollo

Online: 29 April 2024 (05:06:07 CEST)

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